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https://www.readbyqxmd.com/read/29781980/disclosure-coaching-an-ask-tell-ask-model-to-support-clinicians-in-disclosure-conversations
#1
Jo Shapiro, Lynne Robins, Pamela Galowitz, Thomas H Gallagher, Sigall Bell
Error disclosure is a high-stakes, emotionally charged interaction for patients and families as well as clinicians. A failed disclosure can result in emotional distress, reduced patient and family trust, litigation, and lost opportunities to learn from and prevent subsequent errors. However, many clinicians have little expertise in handling these challenging interactions and can inadvertently make a bad situation worse. Even those clinicians who have had formal disclosure training may have trouble remembering what they were taught when faced with the need to actually discuss an error with patients...
May 16, 2018: Journal of Patient Safety
https://www.readbyqxmd.com/read/29781412/imported-cases-and-minimum-temperature-drive-dengue-transmission-in-guangzhou-china-evidence-from-arimax-model
#2
Q L Jing, Q Cheng, J M Marshall, W B Hu, Z C Yang, J H Lu
Dengue is the fastest spreading mosquito-transmitted disease in the world. In China, Guangzhou City is believed to be the most important epicenter of dengue outbreaks although the transmission patterns are still poorly understood. We developed an autoregressive integrated moving average model incorporating external regressors to examine the association between the monthly number of locally acquired dengue infections and imported cases, mosquito densities, temperature and precipitation in Guangzhou. In multivariate analysis, imported cases and minimum temperature (both at lag 0) were both associated with the number of locally acquired infections (P < 0...
May 21, 2018: Epidemiology and Infection
https://www.readbyqxmd.com/read/29779911/piloting-medication-histories-in-a-pediatric-postanesthesia-care-unit
#3
Nathan Lake, Humaira Nawer, Deborah Wagner
PURPOSE: Develop a medication history process for pediatric postanesthesia care unit (PACU) patients to identify discrepancies between home and inpatient medications and prevent medication errors. DESIGN: Pilot an evidence-based practice change to perform PACU medication histories. METHODS: Inpatients or surgical admissions to general care units at a pediatric tertiary care 348-bed hospital ages 2-18 years were included. Parents/guardians were asked about their child's prescription and over-the-counter medications, allergies, and adherence...
May 18, 2018: Journal of Perianesthesia Nursing: Official Journal of the American Society of PeriAnesthesia Nurses
https://www.readbyqxmd.com/read/29779648/how-to-write-an-original-article
#4
L Mateu Arrom, J Huguet, C Errando, A Breda, J Palou
CONTEXT: A correctly drafted original article gives information on what was done, why it was done, how it was done, the result of what was done, and the significance of what was done. Many articles fail to report their results effectively. OBJECTIVE: To describe the characteristics of an original article and to give practical recommendations to prevent the most common errors in our environment. EVIDENCE ACQUISITION: We performed a systematic search of the terms "how to write a scientific article", "structure of the original article" and "publishing an article" in the databases PubMed and SCOPUS...
May 17, 2018: Actas Urologicas Españolas
https://www.readbyqxmd.com/read/29777938/austrian-firearm-legislation-and-its-effects-on-suicide-and-homicide-mortality-a-natural-quasi-experiment-amidst-the-global-economic-crisis
#5
Daniel König, Patrick Swoboda, Robert J Cramer, Christoph Krall, Vita Postuvan, Nestor D Kapusta
BACKGROUND: Restriction of access to suicide methods has been shown to effectively reduce suicide mortality rates. AIMS: To examine how the global economic crisis of 2008 and the firearm legislation reform of 1997 affected suicide and homicide mortality rate within Austria. METHODS: Official data for the years 1985-2016 for firearm certificates, suicide, homicide, unemployment rates and alcohol consumption were examined using auto regressive error and Poisson regression models...
May 16, 2018: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/29776359/evaluation-of-malaria-rapid-diagnostic-test-rdt-use-by-community-health-workers-a-longitudinal-study-in-western-kenya
#6
Matthew R Boyce, Diana Menya, Elizabeth L Turner, Jeremiah Laktabai, Wendy Prudhomme-O'Meara
BACKGROUND: Malaria rapid diagnostic tests (RDTs) are a simple, point-of-care technology that can improve the diagnosis and subsequent treatment of malaria. They are an increasingly common diagnostic tool, but concerns remain about their use by community health workers (CHWs). These concerns regard the long-term trends relating to infection prevention measures, the interpretation of test results and adherence to treatment protocols. This study assessed whether CHWs maintained their competency at conducting RDTs over a 12-month timeframe, and if this competency varied with specific CHW characteristics...
May 18, 2018: Malaria Journal
https://www.readbyqxmd.com/read/29776337/should-statin-guidelines-consider-patient-preferences-eliciting-preferences-of-benefit-and-harm-outcomes-of-statins-for-primary-prevention-of-cardiovascular-disease-in-the-sub-saharan-african-and-european-contexts
#7
Henock G Yebyo, Hélène E Aschmann, Tsung Yu, Milo A Puhan
BACKGROUND: Patient preferences are key parameters to evaluate benefit-harm balance of statins for primary prevention but they are not readily available to guideline developers and decision makers. Our study aimed to elicit patient preferences for benefit and harm outcomes related to use of statins for primary cardiovascular disease prevention and to examine how the preferences differ across economically and socio-culturally different environments. METHODS: We conducted preference-eliciting surveys using best-worst scaling designed with a balanced incomplete-block design (BIBD) on 13 statins-related outcomes on 220 people in Ethiopia and Switzerland...
May 18, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29772890/application-of-decision-tree-for-prediction-of-cutaneous-leishmaniasis-incidence-based-on-environmental-and-topographic-factors-in-isfahan-province-iran
#8
Roghieh Ramezankhani, Nooshin Sajjadi, Roya Nezakati Esmaeilzadeh, Seyed Ali Jozi, Mohammad Reza Shirzadi
Cutaneous Leishmaniasis (CL) is a neglected tropical disease that continues to be a health problem in Iran. Nearly 350 million people are thought to be at risk. We investigated the impact of the environmental factors on CL incidence during the period 2007- 2015 in a known endemic area for this disease in Isfahan Province, Iran. After collecting data with regard to the climatic, topographic, vegetation coverage and CL cases in the study area, a decision tree model was built using the classification and regression tree algorithm...
May 8, 2018: Geospatial Health
https://www.readbyqxmd.com/read/29769718/ankrd16-prevents-neuron-loss-caused-by-an-editing-defective-trna-synthetase
#9
My-Nuong Vo, Markus Terrey, Jeong Woong Lee, Bappaditya Roy, James J Moresco, Litao Sun, Hongjun Fu, Qi Liu, Thomas G Weber, John R Yates, Kurt Fredrick, Paul Schimmel, Susan L Ackerman
Editing domains of aminoacyl tRNA synthetases correct tRNA charging errors to maintain translational fidelity. A mutation in the editing domain of alanyl tRNA synthetase (AlaRS) in Aars sti mutant mice results in an increase in the production of serine-mischarged tRNAAla and the degeneration of cerebellar Purkinje cells. Here, using positional cloning, we identified Ankrd16, a gene that acts epistatically with the Aars sti mutation to attenuate neurodegeneration. ANKRD16, a vertebrate-specific protein that contains ankyrin repeats, binds directly to the catalytic domain of AlaRS...
May 16, 2018: Nature
https://www.readbyqxmd.com/read/29768699/near-infrared-spectrometry-allows-fast-and-extensive-predictions-of-functional-traits-from-dry-leaves-and-branches
#10
Flávia R C Costa, Carla Lang, Danilo R A Almeida, Carolina V Castilho, Lourens Poorter
The linking of individual functional traits to ecosystem processes is the basis for making generalizations in ecology, but the measurement of individual values is laborious and time consuming, preventing large-scale trait mapping. Also, in hyper-diverse systems, errors occur because identification is difficult, and species level values ignore intra-specific variation. To allow extensive trait mapping at the individual level, we evaluated the potential of Fourrier-Transformed Near Infra-Red Spectrometry (FT-NIR) to adequately describe 14 traits that are key for plant carbon, water, and nutrient balance...
May 16, 2018: Ecological Applications: a Publication of the Ecological Society of America
https://www.readbyqxmd.com/read/29768383/treatable-massive-pericardial-effusion-and-hypertrophic-cardiomyopathy-in-an-infant-with-a-novel-homozygous-acadvl-mutation-a-case-report
#11
Yoo-Mi Kim, Geena Kim, Hoon Ko, Han-Wook Yoo, Hyoung Doo Lee
RATIONALE: Infantile-onset hypertrophic cardiomyopathy (HCMP) should be considered a largely genetic condition, although its onset is most often triggered by infection. Very long chain acyl-CoA dehydrogenase (VLCAD) deficiency is a rare autosomal recessive inborn error of mitochondrial fatty acid β-oxidation that often causes severe cardiomyopathy and/or sudden death during the neonatal period. PATIENT CONCERNS: Herein, we report an infant with VLCAD deficiency who presented with severe cardiac manifestations, including massive pericardial effusion and HCMP...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29764796/predicting-the-reasons-of-customer-complaints-a-first-step-toward-anticipating-quality-issues-of-in-vitro-diagnostics-assays-with-machine-learning
#12
Stephane Aris-Brosou, James Kim, Li Li, Hui Liu
BACKGROUND: Vendors in the health care industry produce diagnostic systems that, through a secured connection, allow them to monitor performance almost in real time. However, challenges exist in analyzing and interpreting large volumes of noisy quality control (QC) data. As a result, some QC shifts may not be detected early enough by the vendor, but lead a customer to complain. OBJECTIVE: The aim of this study was to hypothesize that a more proactive response could be designed by utilizing the collected QC data more efficiently...
May 15, 2018: JMIR Medical Informatics
https://www.readbyqxmd.com/read/29761204/-recognition-and-prevention-of-problems-in-lacrimal-duct-surgery
#13
REVIEW
T Kühnel
Surgical management of lacrimal duct obstruction beyond the canaliculi proves to be a promising endeavor in most cases. To realize the full potential of endonasal dacryocystorhinostomy, some aspects of diagnosis and differential indication setting should be considered in order to avoid errors and problems during patient selection, execution of the technical procedure, and communication with ophthalmologists. These issues are described according to the clinical management of patients; current literature is cited...
May 14, 2018: HNO
https://www.readbyqxmd.com/read/29760616/high-frequency-of-primary-hereditary-ichthyoses-in-the-north-east-region-of-cairo-egypt
#14
Nermine El-Sayed, Neveen S Seifeldin, Christine K T Gobrial
Introduction: Inherited ichthyoses are caused by mutations in various genes important for keratinocyte differentiation and epidermal barrier function. Although ichthyoses are rare disorders, they require costly long-term medical management, and thus there is a need for efficient preventive and therapeutic strategies. Aim: We performed a retrospective study to determine the frequency, types, clinical presentation and associated genomic errors of primary hereditary ichthyoses in Egyptian patients and their relatives consulting the Genetics Clinic, Pediatric Hospital, Ain Shams University...
April 2018: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29759903/potential-adverse-drug-events-and-nephrotoxicity-related-to-prophylaxis-with-omeprazole-for-digestive-disorders-a-prospective-cohort-study
#15
Fabiana Rossi Varallo, Tales Rubens de Nadai, Alice Rosa Alves de Oliveira, Patricia de Carvalho Mastroianni
PURPOSE: The purpose of this study was to assess whether prophylaxis for digestive disorders with omeprazole is a risk factor for adverse drug events (ADEs) and kidney impairment. METHODS: This was a 9-month, prospective, double-blinded cohort study performed in a Brazilian public hospital. All inpatients 18 years or older admitted during the period of data collection were divided into 2 cohorts. The first group comprised 200 patients receiving prophylaxis for digestive disorders with omeprazole...
May 11, 2018: Clinical Therapeutics
https://www.readbyqxmd.com/read/29759141/elevated-plasma-macrophage-migration-inhibitor-factor-as-a-risk-factor-for-the-development-of-post-stroke-depression-in-ischemic-stroke
#16
Tingting Xu, Shuang Pu, Ying Ni, Mingqing Gao, Xuemei Li, Xianwei Zeng
BACKGROUND: Macrophage migration inhibitory factor (MIF), a central cytokine of the innate immunity and inflammatory responses, has been reported to link to the pathophysiology of cardiovascular disease and depression. The aim of this study was to test the possible association between plasma MIF and the development of post-stroke depression (PSD) in Chinese patients with acute ischemic stroke (AIS). METHODS: The first-ever AIS patients who were hospitalized at Affiliated Hospital of Weifang Medical College during the period from November 2015 to September 2017 were included...
July 15, 2018: Journal of Neuroimmunology
https://www.readbyqxmd.com/read/29758950/simulated-medication-errors-a-means-of-evaluating-healthcare-professionals-knowledge-and-understanding-of-medication-safety
#17
Hesty Utami Ramadaniati, Jeffery David Hughes, Ya Ping Lee, Lynne Maree Emmerton
OBJECTIVE: To determine multi-disciplinary perceptions of the clinical significance of medication errors (MEs), the responsible health professional(s), the contributing factors and potential preventive strategies. METHODS: The five simulated ME cases represented errors from five wards at a children's hospital in Australia. Pre-determined answers for each case were developed through consensus among the researchers. The root cause analysis (RCA) was undertaken via a questionnaire disseminated to physicians, nurses and pharmacists at the study hospital to seek their opinions on the ME cases...
May 9, 2018: International Journal of Risk & Safety in Medicine
https://www.readbyqxmd.com/read/29757724/neuroimaging-findings-of-organic-acidemias-and-aminoacidopathies
#18
Nihaal Reddy, Sonia F Calloni, Hilary J Vernon, Eugen Boltshauser, Thierry A G M Huisman, Bruno P Soares
Although individual cases of inherited metabolic disorders are rare, overall they account for a substantial number of disorders affecting the central nervous system. Organic acidemias and aminoacidopathies include a variety of inborn errors of metabolism that are caused by defects in the intermediary metabolic pathways of carbohydrates, amino acids, and fatty acid oxidation. These defects can lead to the abnormal accumulation of organic acids and amino acids in multiple organs, including the brain. Early diagnosis is mandatory to initiate therapy and prevent permanent long-term neurologic impairments or death...
May 2018: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29754251/impact-of-medication-reconciliation-and-review-and-counselling-on-adverse-drug-events-and-healthcare-resource-use
#19
Amna Al-Hashar, Ibrahim Al-Zakwani, Tommy Eriksson, Alaa Sarakbi, Badriya Al-Zadjali, Saif Al Mubaihsi, Mohammed Al Zaabi
Background Adverse drug events from preventable medication errors can result in patient morbidity and mortality, and in cost to the healthcare system. Medication reconciliation can improve communication and reduce medication errors at transitions in care. Objective Evaluate the impact of medication reconciliation and counselling intervention delivered by a pharmacist for medical patients on clinical outcomes 30 days after discharge. Setting Sultan Qaboos University Hospital, Muscat, Oman. Methods A randomized controlled study comparing standard care with an intervention delivered by a pharmacist and comprising medication reconciliation on admission and discharge, a medication review, a bedside medication counselling, and a take-home medication list...
May 12, 2018: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/29754215/a-systematic-literature-review-on-strategies-to-avoid-look-alike-errors-of-labels
#20
REVIEW
Karin H M Larmené-Beld, E Kim Alting, Katja Taxis
PURPOSE: Unclear labeling has been recognized as an important cause of look-alike medication errors. The aim of this literature review is to systematically evaluate the current evidence on strategies to minimize medication errors due to look-alike labels. METHODS: A literature search of PubMed and EMBASE for all available years was performed independently by two reviewers. Original studies assessing strategies to minimize medication errors due to look-alike labels focusing on readability of labels by health professionals or consumers were included...
May 12, 2018: European Journal of Clinical Pharmacology
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