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https://www.readbyqxmd.com/read/27114049/thyroid-function-in-patients-with-cystic-fibrosis-no-longer-a-concern
#1
Sun Y Lee, Supavit Chesdachai, Moon J Lee, Xue-Mei He, Vin Tangpricha, Lewis E Braverman
BACKGROUND: Development of goiter and hypothyroidism has been reported in patients with cystic fibrosis (CF) since the 1970s, especially when treated with iodine-based expectorants. With iodine-containing expectorants no longer in routine use, the prevalence of thyroid dysfunction in CF patients is unknown. This cross-sectional study assessed thyroid function status in a large cohort of CF patients. METHODS: Sera from ambulatory subjects were obtained from an Institutional Review Board (IRB)-approved biorepository of patients seen at the Emory CF Center between January 1, 2011, and December 31, 2014...
July 2016: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/25264682/the-role-of-cities-in-reducing-smoking-in-china
#2
Pamela Redmon, Jeffrey Koplan, Michael Eriksen, Shuyang Li, Wang Kean
China is the epicenter of the global tobacco epidemic. China grows more tobacco, produces more cigarettes, makes more profits from tobacco and has more smokers than any other nation in the world. Approximately one million smokers in China die annually from diseases caused by smoking, and this estimate is expected to reach over two million by 2020. China cities have a unique opportunity and role to play in leading the tobacco control charge from the "bottom up". The Emory Global Health Institute-China Tobacco Control Partnership supported 17 cities to establish tobacco control programs aimed at changing social norms for tobacco use...
2014: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/24195020/prognosis-and-epidemiology-of-amyotrophic-lateral-sclerosis-analysis-of-a-clinic-population-1997-2011
#3
Kim Traxinger, Crystal Kelly, Brent A Johnson, Robert H Lyles, Jonathan D Glass
Amyotrophic lateral sclerosis is a disease with highly variable clinical features and prognosis. We analyzed the prognostic indicators of age, sex, bulbar or spinal onset, body mass index (BMI), and forced vital capacity (FVC) for 728 deceased patients from the Emory ALS Clinic. The median overall survival was 29.8 months from symptom onset, 15.8 months from diagnosis, and 14.3 months from the initial clinic visit. While univariate analyses revealed that each of the identified clinical features was strongly associated with patient survival, in multivariable analyses only age, BMI, and FVC measured at the first clinic visit were independent prognostic indicators; bulbar onset and sex were not significantly associated with survival prognosis after adjustment for the other clinical features...
August 2013: Neurology. Clinical Practice
https://www.readbyqxmd.com/read/23791163/surgical-biopsy-of-suspected-interstitial-lung-disease-is-superior-to-radiographic-diagnosis
#4
COMPARATIVE STUDY
Michael O Kayatta, Shair Ahmed, Josh A Hammel, Felix Fernandez, Allan Pickens, Daniel Miller, Gerald Staton, Srihari Veerarghavan, Seth Force
BACKGROUND: Different modalities are used to diagnose interstitial lung disease. We compared the effectiveness of minimally invasive surgical biopsy versus high-resolution computed tomography for the diagnosis of interstitial lung disease and report the mortality of the procedure. METHODS: We reviewed 194 patients undergoing video-assisted thoracoscopic lung biopsies for the suspicion of interstitial lung disease from January 2003 to February 2012 at Emory University...
August 2013: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/23245447/the-impact-of-specific-preoperative-organ-dysfunction-in-patients-undergoing-aortic-valve-replacement
#5
COMPARATIVE STUDY
Vinod H Thourani, Ritam Chowdhury, Rebecca L Gunter, Patrick D Kilgo, Edward P Chen, John D Puskas, Michael E Halkos, Omar M Lattouf, William A Cooper, Robert A Guyton
BACKGROUND: Optimizing treatment strategies to risk profile patients undergoing aortic valve replacement remains a priority. The role that specific and combinations of preoperative organ dysfunction (OD) plays in informing these decisions remains uncertain. This study sought to determine the relative effect that OD in particular systems has on short- and long-term outcomes. METHODS: A total of 1,759 aortic valve replacement cases with and without coronary artery bypass grafting performed from January 2002 to June 2010 at Emory University are the basis for this retrospective analysis...
March 2013: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/23213415/nuclear-smad7-overexpressed-in-mesenchymal-cells-acts-as-a-transcriptional-corepressor-by-interacting-with-hdac-1-and-e2f-to-regulate-cell-cycle
#6
Takashi Emori, Koki Kitamura, Kenji Okazaki
Smad family proteins are essential intracellular mediators that regulate transforming growth factor-β (TGF-β) ligand signaling. In response to diverse stimuli, Smad7 is rapidly expressed and acts as a cytoplasmic inhibitor that selectively interferes with signals elicited from TGF-β family receptors. In addition, earlier works have indicated that retrovirally transduced Smad7 induces long-lasting cell proliferation arrest in a variety of mesenchymal cells through down-regulation of G1 cyclins. However, the molecular mechanisms underlying the cytostatic effects of Smad7 remain unknown...
March 15, 2012: Biology Open
https://www.readbyqxmd.com/read/23000441/mammography-rates-after-the-2009-us-preventive-services-task-force-breast-cancer-screening-recommendation
#7
David H Howard, E Kathleen Adams
OBJECTIVE: To measure the impact of the 2009 US Preventive Services Task Force (USPSTF) breast cancer screening recommendation, which recommended against routine screening for women aged 40 to 49 and stated that there was "insufficient evidence" to recommend screening for women aged 75 and older, on mammography rates. METHODS: Self-reported mammography rates were calculated using the 2006-2010 Medical Expenditure Panel Surveys (n=29,857). The paper reports mammography rates by age group (40 to 49, 50 to 74, and 75 and older), adjusted for age, race/ethnicity, socioeconomic status, and region...
November 2012: Preventive Medicine
https://www.readbyqxmd.com/read/21830396/supplementation-before-endoscopic-therapy-for-esophageal-varices-reduces-mental-stress-in-patients-with-liver-cirrhosis
#8
RANDOMIZED CONTROLLED TRIAL
Minoru Itou, Takumi Kawaguchi, Eitaro Taniguchi, Tetsuharu Oriishi, Takuro Suetsugu, Risa Hano, Miku Yoshihara, Midori Takishita, Mayumi Eguchi, Yukari Ogiwara, Juri Otsuyama, Michiko Mutou, Ryoko Ibi, Ryoko Akiyama, Midori Ono, Momoka Otsuka, Ayu Nagamatsu, Suiko Tanaka, Kenji Miyakoda, Keigo Emori, Yukihiko Morita, Masafumi Kumamoto, Osamu Tsuruta, Michio Sata
BACKGROUND/AIMS: Esophageal varices are often seen in cirrhotic patients. Because endoscopic therapy for esophageal varices forces such patients to go on an extended fast until the endoscopic therapy occurs, physical and psychological stresses are induced. The aims of this study were to investigate the effects of a nutritional supplement before endoscopic therapy on such stresses, and on the safety of therapy. METHODOLOGY: Thirty-six cirrhotic patients with esophageal varices were enrolled in this study and classified into two groups...
May 2011: Hepato-gastroenterology
https://www.readbyqxmd.com/read/21562440/keratoconus-unmasked-by-unilateral-ptosis-repair
#9
Evan C Sussenbach, Dilip A Thomas, Emory G Patterson, David D Bogorad
Astigmatic changes have been shown to occur after ptosis repair due to the altered vector forces on the underlying cornea from the repositioned upper eyelid. The astigmatic change is usually transient, but it may affect a patient's vision for at least the first few months after surgery. The authors present a case of a patient who underwent ptosis repair and subsequently developed postoperative decline in best-corrected visual acuity due to previously undiagnosed keratoconus. The patient's irregular astigmatism seems to have been masked by the ptotic upper eyelid, which we postulate to have acted similar to a stenopaic slit...
March 2012: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/21367565/thoracic-endovascular-repair-as-a-safe-management-strategy-for-aortobronchial-fistulas
#10
Charles J Bailey, Seth Force, Ross Milner, Karthikeshwar Kasirajan, Ravi K Veeraswamy
OBJECTIVES: This study assessed the safety and efficacy of thoracic endovascular aortic repair (TEVAR) in the management of aortobronchial fistulas. METHODS: A retrospective review was performed at Emory University Hospital to identify all patients who presented with an aortobronchial fistula. The diagnosis was based on clinical, radiologic, and bronchoscopic findings. Patients who underwent TEVAR as definitive management of these fistulas were identified. Demographics, history of thoracic aorta pathology or intervention, type and number of endografts used, need for reoperation, and clinical and radiologic follow-up data were collected for each individual...
May 2011: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/21127165/using-robot-applied-resistance-to-augment-body-weight-supported-treadmill-training-in-an-individual-with-incomplete-spinal-cord-injury
#11
Tania Lam, Katherine Pauhl, Andrei Krassioukov, Janice J Eng
BACKGROUND AND PURPOSE: The efficacy of task-specific gait training for people with spinal cord injury (SCI) is premised on evidence that the provision of gait-related afferent feedback is key for the recovery of stepping movements. Recent findings have shown that sensory feedback from flexor muscle afferents can facilitate flexor muscle activity during the swing phase of walking. This case report was undertaken to determine the feasibility of using robot-applied forces to resist leg movements during body-weight-supported treadmill training (BWSTT) and to measure its effect on gait and other health-related outcomes...
January 2011: Physical Therapy
https://www.readbyqxmd.com/read/20417779/video-assisted-thoracoscopic-surgery-segmentectomy-a-safe-and-effective-procedure
#12
COMPARATIVE STUDY
Bradley G Leshnower, Daniel L Miller, Felix G Fernandez, Allan Pickens, Seth D Force
BACKGROUND: Anatomic sublobar resection is currently being assessed as an alternative to lobectomy for primary lung cancers less than 2 cm in size. Open segmentectomy is a proven oncologic procedure for patients with reduced cardiopulmonary reserve and significant comorbidities. With the increased use of thoracoscopy, a video-assisted thoracoscopic surgery (VATS) segmentectomy may be as safe and effective as an open segmentectomy. METHODS: We performed a retrospective review of patients who underwent a segmentectomy between May 2002 and March 2009 at Emory University Hospital...
May 2010: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/20148028/the-next-generation-of-scenarios-for-climate-change-research-and-assessment
#13
Richard H Moss, Jae A Edmonds, Kathy A Hibbard, Martin R Manning, Steven K Rose, Detlef P van Vuuren, Timothy R Carter, Seita Emori, Mikiko Kainuma, Tom Kram, Gerald A Meehl, John F B Mitchell, Nebojsa Nakicenovic, Keywan Riahi, Steven J Smith, Ronald J Stouffer, Allison M Thomson, John P Weyant, Thomas J Wilbanks
Advances in the science and observation of climate change are providing a clearer understanding of the inherent variability of Earth's climate system and its likely response to human and natural influences. The implications of climate change for the environment and society will depend not only on the response of the Earth system to changes in radiative forcings, but also on how humankind responds through changes in technology, economies, lifestyle and policy. Extensive uncertainties exist in future forcings of and responses to climate change, necessitating the use of scenarios of the future to explore the potential consequences of different response options...
February 11, 2010: Nature
https://www.readbyqxmd.com/read/19747837/does-video-assisted-thoracoscopic-lobectomy-for-lung-cancer-provide-improved-functional-outcomes-compared-with-open-lobectomy
#14
John R Handy, James W Asaph, Emory Charles Douville, Gary Y Ott, Gary L Grunkemeier, Yingxing Wu
OBJECTIVE: We evaluated video-assisted thoracic surgery (VATS) and open (OPEN) lobectomy for lung cancer and impact upon 6-month postoperative (postop) functional health status and quality of life. METHODS: In this retrospective analysis of prospective, observational data, anatomic lobectomy with staging thoracic lymphadenectomy was performed with curative intent for lung cancer. OPEN consisted of either thoracotomy (TH) or median sternotomy (MS). Technique was selected on the basis of anatomic imperative (OPEN: larger or central; VATS smaller or peripheral tumours) and/or surgical skills (VATS lobectomy initiated in 2001)...
February 2010: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/18850913/human-dynamics-revealed-through-web-analytics
#15
Bruno Gonçalves, José J Ramasco
The increasing ubiquity of Internet access and the frequency with which people interact with it raise the possibility of using the Web to better observe, understand, and monitor several aspects of human social behavior. Web sites with large numbers of frequently returning users are ideal for this task. If these sites belong to companies or universities, their usage patterns can furnish information about the working habits of entire populations. In this work, we analyze the properly anonymized logs detailing the access history to Emory University's Web site...
August 2008: Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics
https://www.readbyqxmd.com/read/16534178/bronchoalveolar-lavage-fluid-d-dimer-levels-are-higher-and-more-prevalent-in-black-patients-with-pulmonary-sarcoidosis
#16
MULTICENTER STUDY
Rafael L Perez, Anthony P Kimani, Talmadge E King, Samuel M Aguayo, Jesse Roman et al.
BACKGROUND: Abnormalities of lung coagulation and fibrinolysis in sarcoidosis are thought to play a role in the pathogenesis of this disease. OBJECTIVE: We previously showed that bronchoalveolar lavage fluid (BALF) D dimer directly correlated with various measures of severity in sarcoidosis. Here, we analyze our observation that BALF D dimer was more frequently found at higher levels in African-American patients with pulmonary sarcoidosis. METHODS: BALF D dimer was measured in 55 subjects with pulmonary sarcoidosis and 31 healthy volunteers by enzyme immunoassay...
2007: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/15434792/the-international-council-of-nurses-a-world-force-in-nursing
#17
F H M EMORY
No abstract text is available yet for this article.
September 1950: Canadian Nurse
https://www.readbyqxmd.com/read/12922169/quaternary-structure-of-the-neuronal-protein-nap-22-in-aqueous-solution
#18
Richard M Epand, Emory H Braswell, Christopher M Yip, Raquel F Epand, Shohei Maekawa
NAP-22, a myristoylated, anionic protein, is a major protein component of the detergent-insoluble fraction of neurons. After extraction from the membrane, it is readily soluble in water. NAP-22 will partition only into membranes with specific lipid compositions. The lipid specificity is not expected for a monomeric myristoylated protein. We have studied the self-association of NAP-22 in solution. Sedimentation velocity experiments indicated that the protein is largely associated. The low concentration limiting s value is approximately 1...
August 21, 2003: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/8633960/lung-volume-reduction-surgery-lessons-learned
#19
J I Miller, R B Lee, K A Mansour
BACKGROUND: The concept of lung volume reduction for generalized emphysema was proposed by Brantigan and associates in 1958 and reintroduced by Cooper and colleagues in 1994. The present study presents lessons learned from an 18-month experience. METHODS: From August 1, 1994, to August 1, 1995, 53 patients underwent lung volume reduction at Emory University for generalized emphysema. There were 17 women and 36 men ranging in age from 55 to 75 years. The length of stay ranged from 10 to 59 days...
May 1996: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/8145708/recommendations-of-the-international-task-force-for-disease-eradication
#20
(no author information available yet)
This report summarizes the conclusions of the International Task Force for Disease Eradication (ITFDE), a group of scientists who were convened by a secretariat at the Carter Center of Emory University six times during 1989-1992. The purpose of the ITFDE was to establish criteria and apply them systematically to evaluate the potential eradicability of other diseases in the aftermath of the Smallpox Eradication Program. The ITFDE defined eradication as "reduction of the worldwide incidence of a disease to zero as a result of deliberate efforts, obviating the necessity for further control measures...
December 31, 1993: MMWR. Recommendations and Reports: Morbidity and Mortality Weekly Report. Recommendations and Reports
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