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Melanoma cardiothoracic

Charles J Puza, Adela R Cardones, Paul J Mosca
Importance: The immunosuppression vital to maintaining transplanted organs comes with an increased incidence of cutaneous neoplasms. Understanding the genesis of malignant melanoma (MM) in transplant subpopulations is necessary for adequate disease surveillance. Objective: To determine the incidence and timing of presentation of MM in the cardiothoracic (heart and/or lung) transplant (CTT) population. Design, Setting, and Participants: This was a retrospective cohort study of 1164 patients who underwent a CTT from 2001 through 2016 with a median follow-up time of 4...
February 16, 2018: JAMA Dermatology
J F Buell, J Trofe, M J Hanaway, A Lo, B Rosengard, H Rilo, R Alloway, T Beebe, M R First, E S Woodle
BACKGROUND: The demand for transplantable organs exceeds donor supply. Patients with central nervous system (CNS) or other tumors are controversial donors, and the donor cancer transmission rates in cardiothoracic transplant recipients have not been determined. The Israel Penn International Transplant Tumor Registry (IPITTR) was queried to define the risk of donor cancer transmission in cardiothoracic transplant recipients. METHODS: All heart, lung, or heart-lung recipients of organs from donors with a history of malignancy were reviewed...
October 2001: Surgery
S Bangratz
UNLABELLED: ACUTE REJECTION: Endomyocardial biopsy is the most reliable method to detect acute rejection but is an invasive procedure. Other non-invasive methods have been proposed including tissular Doppler ultrasonography with analysis of the posterior wall velocity and teletransmitted study of the intramyocardial amplitude of the QRS complex. Adding plasmapheresis to the conventional treatment is helpful in improving survival and reducing the incidence of late coronary disease after severe acute reflection...
September 1, 2001: La Presse M├ędicale
M J Veness, D I Quinn, C S Ong, A M Keogh, P S Macdonald, S G Cooper, G W Morgan
BACKGROUND: The development of malignancies in recipients of a cardiothoracic transplant (CTT)--that is, heart, lung, or heart and lung recipients-is of concern. Cutaneous and lymphoproliferative malignancies comprise the two major groups of malignancies encountered. A small subgroup of patients will develop potentially life-threatening aggressive cutaneous malignancies (ACM); these are poorly defined and documented in the literature. The authors report the results for 619 CTT recipients from a single institution...
April 15, 1999: Cancer
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