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https://www.readbyqxmd.com/read/28325614/gothic-aortic-arch-and-cardiac-mechanics-in-young-patients-after-arterial-switch-operation-for-d-transposition-of-the-great-arteries
#1
Giovanni Di Salvo, Ziad Bulbul, Valeria Pergola, Ziad Issa, Ghassan Siblini, Nisreen Muhanna, Domenico Galzerano, Bahaa Fadel, Mansour Al Joufan, Majid Al Fayyadh, Zohair Al Halees
BACKGROUND: In patients who have undergone arterial switch operation (ASO) for d-transposition of the great arteries a gothic aortic arch (GA) morphology has been found and it has been associated with abnormal aortic bio-elastic properties. HYPOTHESIS: GA is frequent in ASO patients and may have an impact on cardiac mechanics. Our study aims were to assess 1- the occurrence of GA in a large sample of patients after ASO; 2- the association between GA and aortic bio-elastic properties; and 3- the impact of GA on left ventricular (LV) function using speckle tracking echocardiography (STE)...
March 11, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28160298/fluoroless-catheter-ablation-of-cardiac-arrhythmias-a-5-year-experience
#2
Mansour Razminia, M Cameron Willoughby, Hany Demo, Hesam Keshmiri, Theodore Wang, Oliver J D'Silva, Terry A Zheutlin, Hakeem Jibawi, Paul Okumale, Richard F Kehoe
BACKGROUND: Catheter ablations have been traditionally performed with the use of fluoroscopic guidance, which exposes the patient and staff to the inherent risks of radiation. We have developed techniques to eliminate the use of fluoroscopy during cardiac ablations and have been performing completely fluoroless catheter ablations on our patients for over 5 years. METHODS: We present a retrospective analysis of the safety, efficacy, and feasibility data from 500 consecutive patients who underwent nonfluoroscopic catheter ablation, targeting a total of 639 arrhythmias, including atrioventricular reciprocating tachycardia (AVRT), atrioventricular nodal reentrant tachycardia (AVNRT), atrial tachycardia (AT), atrial fibrillation (AF), premature ventricular contractions (PVC), and ventricular tachycardia (VT)...
February 3, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28152766/outcome-analysis-of-breast-cancer-patients-treated-with-cardiotoxic-agents-in-the-community-setting-a-single-institution-experience
#3
Munthir Mansour, Todd W Gress, Maria R B Tria Tirona
213 Background: Anthracyclines and anti-Her-2 targeted therapy are commonly used effective breast cancer treatments. They are known to decrease Left Ventricular Ejection Fraction (LVEF), which may increase patients' morbidity and mortality. There is currently no consensus on post treatment cardiac follow-up. Recent observations suggested that ACEI and B blocker drugs could have cardioprotective effects. We conducted a retrospective study to assess patients' cardiac outcome using post-treatment LVEF follow-up and effect of ACEI and B blocker on cardiac outcome for breast cancer patients who received cardiotoxic agents in our institution...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28116921/effect-of-silver-nanoparticles-synthesized-by-gamma-radiation-on-the-cytotoxicity-of-doxorubicin-in-human-cancer-cell-lines-and-experimental-animals
#4
H H Mansour, M Eid, M B El-Arnaouty
Silver nanoparticles (AgNPs)embedded poly ( N-vinylpyrrolidone/dextran) hydrogels were prepared by gamma radiation. Highly stable and uniformly distributed AgNPs have been obtained within hydrogel networks as nanoreactors via in situ reduction of silver nitrate using sodium borohydride as reducing agent. The formation of AgNPs has been confirmed by Fourier transform infrared spectroscopy. The ultraviolet-visible spectroscopy measurements show a distinct characteristic absorption peaks around 420 nm, indicating the formation of AgNPs...
January 1, 2017: Human & Experimental Toxicology
https://www.readbyqxmd.com/read/28104089/prediction-of-radiofrequency-ablation-lesion-formation-using-a-novel-temperature-sensing-technology-incorporated-in-a-force-sensing-catheter
#5
Guy Rozen, Leon Ptaszek, Israel Zilberman, Kevin Cordaro, E Kevin Heist, Christopher Beeckler, Andres Altmann, Zhang Ying, Zhenjiang Liu, Jeremy N Ruskin, Assaf Govari, Moussa Mansour
BACKGROUND: Real-time radiofrequency (RF) ablation lesion assessment is a major unmet need in cardiac electrophysiology. OBJECTIVE: The purpose of this study was to assess whether improved temperature measurement using a novel thermocoupling (TC) technology combined with information derived from impedance change, contact force (CF) sensing, and catheter orientation allows accurate real-time prediction of ablation lesion formation. METHODS: RF ablation lesions were delivered in the ventricles of 15 swine using a novel externally irrigated-tip catheter containing 6 miniature TC sensors in addition to force sensing technology...
February 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28051221/contribution-of-cardiac-magnetic-resonance-imaging-in-the-diagnosis-of-acute-coronary-syndrome-with-normal-coronary-angiography
#6
Rana Dahmani, Rim Ben Said, Younes Arous, Houaida Mahfoudhi, Chedia Chourabi, Mehdi Ghommidh, Badii Jedaida, Nizar Ben Mansour, Abdeddayem Haggui, Nadhem Hajlaoui, Dhaker Lahidheb, Wafa Fehri, Habib Haouala
Background - Acute coronary syndrome with high level of troponin is a common pattern for emergency consultation. In 10% of cases, coronary angiography concluded that there were no significant coronary lesions. The contribution of cardiac magnetic resonance imaging (MRI) in the etiological investigation is increasing in these conditions. Aim - We analyzed the diagnostic value of cardiac MRI in case of acute coronary syndromes with elevated troponin and normal coronary angiography. Methods - It's a retrospective analytical study including 31 patients presenting with acute coronary syndrome with positive troponins and normal coronary angiography...
June 2016: La Tunisie Médicale
https://www.readbyqxmd.com/read/28032050/discrepancies-between-dental-and-medical-records-of-cardiac-patients-in-alhada-armed-forces-hospital-taif-saudi-arabia
#7
Sana M Al Hibshi, Rajaa M Al-Raddadi, Mansour K Assery
AIMS AND OBJECTIVES: This study aims to estimate the prevalence of medical information discrepancies between dental and medical records of cardiac patients at AlHada Armed Forces Hospital in Taif and to identify the factors contributing to these information discrepancies. MATERIALS AND METHODS: The study applied a descriptive retrospective medical and dental records review of a stratified proportional sample of 289 cardiac patients, which was extracted from 1154 cardiac patients who visited both the cardiology and dental clinics at the AlHada Armed Forces Hospital between 2007 and June 2012...
November 2016: Journal of International Society of Preventive & Community Dentistry
https://www.readbyqxmd.com/read/28024553/sustained-performance-of-a-physicianless-system-of-automated-prehospital-stemi-diagnosis-and-catheterization-laboratory-activation
#8
Brian J Potter, Alexis Matteau, Samer Mansour, Charbel Naim, Mounir Riahi, Richard Essiambre, Martine Montigny, Isabelle Sareault, François Gobeil
BACKGROUND: Treatment times for primary percutaneous coronary intervention frequently exceed the recommended maximum delay. Automated "physicianless" systems of prehospital cardiac catheterization laboratory (CCL) activation show promise, but have been met with resistance over concerns regarding the potential for false positive and inappropriate activations (IAs). METHODS: From 2010 to 2015, first responders performed electrocardiograms (ECGs) in the field for all patients with a complaint of chest pain or dyspnea...
January 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/27862875/cost-awareness-decreases-total-percutaneous-coronary-intervention-procedural-cost-the-shopping-show-how-options-in-price-for-procedures-can-be-influenced-greatly-trial
#9
Elad Asher, John Mansour, Adam Wheeler, Daniel Kendrick, Michael Cunningham, Sahil Parikh, David Zidar, Todd Harford, Daniel I Simon, Vikram S Kashyap
OBJECTIVES: We initiated the SHOPPING Trial (Show How Options in Price for Procedures can be InflueNced Greatly) to see if percutaneous coronary intervention (PCI) procedures can be performed at a lower cost in a single institution. BACKGROUND: Procedural practice variability is associated with inefficiency and increased cost. We hypothesized that announcing costs for all supplies during a catheterization procedure and reporting individual operator cost relative to peers would spur cost reduction without affecting clinical outcomes...
November 10, 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27815344/sealing-intermediate-nonobstructive-coronary-saphenous-vein-graft-lesions-with-drug-eluting-stents-as-a-new-approach-to-reducing-cardiac-events-a-randomized-controlled-trial
#10
Josep Rodés-Cabau, Sanjit S Jolly, John Cairns, Samer Mansour, Philippe L L'Allier, Patrick J Teefy, John J Graham, Michel R Le May, Warren J Cantor, David Wood, Kumar Balasubramanian, Robert DeLarochellière, Vlad Dzavik
BACKGROUND: The objective of this study was to assess the efficacy of sealing intermediate nonobstructive coronary saphenous vein graft (SVG) lesions with drug-eluting stents (DES; paclitaxel- or everolimus-eluting stents) for reducing major adverse cardiac events (MACE). METHODS AND RESULTS: This was a randomized controlled multicenter clinical trial that enrolled patients with a previous coronary artery bypass graft who had developed at least 1 intermediate nonobstructive SVG lesion (30%-60% diameter stenosis by visual estimation)...
November 2016: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/27797291/everolimus-eluting-stents-or-bypass-surgery-for-left-main-coronary-artery-disease
#11
RANDOMIZED CONTROLLED TRIAL
Gregg W Stone, Joseph F Sabik, Patrick W Serruys, Charles A Simonton, Philippe Généreux, John Puskas, David E Kandzari, Marie-Claude Morice, Nicholas Lembo, W Morris Brown, David P Taggart, Adrian Banning, Béla Merkely, Ferenc Horkay, Piet W Boonstra, Ad J van Boven, Imre Ungi, Gabor Bogáts, Samer Mansour, Nicolas Noiseux, Manel Sabaté, José Pomar, Mark Hickey, Anthony Gershlick, Pawel Buszman, Andrzej Bochenek, Erick Schampaert, Pierre Pagé, Ovidiu Dressler, Ioanna Kosmidou, Roxana Mehran, Stuart J Pocock, A Pieter Kappetein
Background Patients with obstructive left main coronary artery disease are usually treated with coronary-artery bypass grafting (CABG). Randomized trials have suggested that drug-eluting stents may be an acceptable alternative to CABG in selected patients with left main coronary disease. Methods We randomly assigned 1905 eligible patients with left main coronary artery disease of low or intermediate anatomical complexity to undergo either percutaneous coronary intervention (PCI) with fluoropolymer-based cobalt-chromium everolimus-eluting stents (PCI group, 948 patients) or CABG (CABG group, 957 patients)...
December 8, 2016: New England Journal of Medicine
https://www.readbyqxmd.com/read/27665225/the-impact-cabg-trial-a-multicenter-randomized-clinical-trial-of-cd133-stem-cell-therapy-during-coronary-artery-bypass-grafting-for-ischemic-cardiomyopathy
#12
Nicolas Noiseux, Samer Mansour, Richard Weisel, Louis-Mathieu Stevens, Shant Der Sarkissian, Katherine Tsang, Andrew M Crean, Eric Larose, Shu-Hong Li, Bernd Wintersperger, Minh Quan Vu, Ignacio Prieto, Ren-Ke Li, Denis Claude Roy, Terrence M Yau
OBJECTIVES: The IMPACT-CABG trial is the first North American multicenter phase II randomized study of intramyocardial delivery of autologous CD133(+) stem cells in patients with chronic ischemic cardiomyopathy undergoing coronary artery bypass grafting. The primary objective was to demonstrate safety, including freedom from major adverse cardiac events. The secondary objective was to evaluate feasibility of same-day autologous cell preparation. Although the trial was not powered to evaluate LV function, exploratory data were collected...
August 13, 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27627223/obesity-serum-resistin-and-leptin-levels-linked-to-coronary-artery-disease
#13
Farzaneh Montazerifar, Ahmad Bolouri, Raheleh Sharifian Paghalea, Mahbubeh Khodadadpour Mahani, Mansour Karajibani
BACKGROUND: Clinical studies have demonstrated that adipocytokines play an important role in developing atherosclerotic cardiovascular diseases. OBJECTIVE: The aim of study was to evaluate the relationship between serum resistin and leptin levels with obesity and coronary artery disease (CAD). METHODS: In a cross-sectional study, we assessed the levels of serum resistin and leptin, C-reactive protein (CRP), lipid profile and cardiac enzyme tests (AST, CPK, LDH, CK-MB) in 40 CAD patients compared to 40 healthy controls...
October 2016: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/27608980/treatment-with-rhus-tripartita-extract-curtails-isoproterenol-elicited-cardiotoxicity-and-oxidative-stress-in-rats
#14
Abdelaaty A Shahat, Mansour S Alsaid, Syed Rafatullah, Mohammed O Al-Sohaibani, Mohammad K Parvez, Mohammed S Al-Dosari, Vassiliki Exarchou, Luc Pieters
BACKGROUND: Consumption of plant-derived nutraceuticals and crude drugs in traditional medicine is widely believed to confer beneficial effects in thwarting the progression of cardiovascular diseases. Rhus tripartita (family Anacardiaceae) has been traditionally used to treat a wide range of ailments. METHODS: In the present study we investigated the protective effects of an alcoholic extract of the stem part of Rhus tripartita male genotype (RTSM) on experimentally induced myocardial injury in rats...
September 8, 2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27562944/left-ventricular-mechanics-in-patients-with-abnormal-origin-of-the-left-main-coronary-artery-from-the-pulmonary-trunk-late-after-successful-repair
#15
Giovanni Di Salvo, Ghassan Siblini, Ziad Issa, Habdan Mohammed, Anas Abu Hazeem, Valeria Pergola, Nisreen Muhanna, Naif Al Qweai, Domenico Galzerano, Bahaa Fadel, Majid Fayyadh, Mansour Joufan, Zohair Halees, Ziad Bulbul
OBJECTIVE: Our aim was to evaluate left ventricular (LV) mechanics by using speckle tracking echocardiography (STE) in asymptomatic patients with abnormal origin of the left main coronary artery from the pulmonary trunk (ALCAPA), late after successful repair, in the presence of LV ejection fraction (EF) >50%. METHODS: We studied 30 ALCAPA patients (median age 4 years, range 1-25 years, NYHA class I, LVEF >50%) and 16 healthy age- and sex-matched controls (median age 5 years, range 1-25 years)...
2017: Cardiology
https://www.readbyqxmd.com/read/27206910/effect-of-a-multidisciplinary-approach-for-the-management-of-patients-with-atrial-fibrillation-in-the-emergency-department-on-hospital-admission-rate-and-length-of-stay
#16
Leon M Ptaszek, Benjamin White, Steven A Lubitz, Anthony P Carnicelli, E Kevin Heist, Patrick T Ellinor, Monique Machado, Jason H Wasfy, Jeremy N Ruskin, Katrina Armstrong, David F Brown, Paul D Biddinger, Moussa Mansour
Management of atrial fibrillation (AF) in the emergency department (ED) is variable because of the absence of universally adopted treatment guidelines. To address potentially preventable hospital admissions and prolonged length of stay, an AF treatment pathway was co-developed by physicians from the cardiac electrophysiology service and the department of emergency medicine at our institution. The impact of this AF pathway on patient outcomes was evaluated with a prospective, observational study conducted in a single tertiary care center from July 1, 2013, to June 30, 2014...
July 1, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/26993493/arrhythmogenic-ventricular-cardiomyopathy-and-sudden-cardiac-death-left-or-right
#17
Rachoin Rachoin, Bernard Abi Saleh, Bilal Mansour, Rayan Jo Rachwan, Wael AlJaroudi
Arrhythmogenic right ventricular cardiomyopathy is a leading cause of sudden cardiac death among athletes in Italy and the Mediterranean region. Although it often involves the right ventricle causing scarring, dilation, systolic impairment with aneurysm formation, it can also involve the left ventricle or present as isolated left ventricular cardiomyopathy. Cardiac magnetic resonance imaging is considered the gold standard in confirming the diagnosis. We summarize four cases of arrhythmogenic ventricular cardiomyopathy with different presentations observed over the past 2 years...
March 18, 2016: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/26878275/contrasting-cardiovascular-mortality-trends-in-eastern-mediterranean-populations-contributions-from-risk-factor-changes-and-treatments
#18
Julia Critchley, Simon Capewell, Martin O'Flaherty, Niveen Abu-Rmeileh, Samer Rastam, Olfa Saidi, Kaan Sözmen, Azza Shoaibi, Abdullatif Husseini, Fouad Fouad, Nadia Ben Mansour, Wafa Aissi, Habiba Ben Romdhane, Belgin Unal, Piotr Bandosz, Kathleen Bennett, Mukesh Dherani, Radwan Al Ali, Wasim Maziak, Hale Arık, Gül Gerçeklioğlu, Deniz Utku Altun, Hatice Şimşek, Sinem Doganay, Yücel Demiral, Özgür Aslan, Nigel Unwin, Peter Phillimore, Nourredine Achour, Waffa Aissi, Riadh Allani, Chokra Arfa, Heidar Abu-Kteish, Niveen Abu-Rmeileh, Radwan Al Ali, Deniz Altun, Balsam Ahmad, Hale Arık, Özgür Aslan, Latifa Beltaifa, Nadia Ben Mansour, Kathleen Bennett, Habiba Ben Romdhane, Nabil Ben Salah, Marissa Collins, Julia Critchley, Simon Capewell, Mukesh Dherani, Yücel Demiral, Sinem Doganay, Madonna Elias, Gül Ergör, Ibtihal Fadhil, Fouad Fouad, Gül Gerçeklioğlu, Rula Ghandour, Sibel Göğen, Abdullatif Husseini, Samer Jaber, Sibel Kalaca, Rana Khatib, Rasha Khatib, Saer Koudsie, Bülent Kilic, Olfa Lassoued, Helen Mason, Wasim Maziak, Maher Abou Mayaleh, Nahed Mikki, Ghmaez Moukeh, Martin O Flaherty, Peter Phillimore, Samer Rastam, Gojka Roglic, Olfa Saidi, Gül Saatli, Ilhan Satman, Azza Shoaibi, Hatice Şimşek, Nesrien Soulaiman, Kaan Sözmen, Faten Tlili, Belgin Unal, Nigel Unwin, Nazan Yardim, Shahaduz Zaman
BACKGROUND: Middle income countries are facing an epidemic of non-communicable diseases, especially coronary heart disease (CHD). We used a validated CHD mortality model (IMPACT) to explain recent trends in Tunisia, Syria, the occupied Palestinian territory (oPt) and Turkey. METHODS: Data on populations, mortality, patient numbers, treatments and risk factor trends from national and local surveys in each country were collated over two time points (1995-97; 2006-09); integrated and analysed using the IMPACT model...
April 1, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/26776662/-ajwa-dates-phoenix-dactylifera-l-extract-ameliorates-isoproterenol-induced-cardiomyopathy-through-downregulation-of-oxidative-inflammatory-and-apoptotic-molecules-in-rodent-model
#19
Mohammed Al-Yahya, Mohammad Raish, Mansour S AlSaid, Ajaz Ahmad, Ramzi A Mothana, Mohammed Al-Sohaibani, Mohammed S Al-Dosari, Mohammad K Parvez, Syed Rafatullah
BACKGROUND/PURPOSE: Ajwa, a special variety of Saudi Arabian dates (Phoenix dactylifera L.) is a rich source of nutrients, fibers and bioactive molecules. While previous studies have shown the therapeutic value of dates phytoconstituents in liver and kidney diseases etc., its cardioprotective potential remains elusive. We therefore, investigated the cardioprotective effect of lyophilized Ajwa extract (AJLE) ex vivo as well as in vivo. METHODS: Ex vivo cardioprotective effect of AJLE was evaluated on DCFH-toxicated cardiomyoblast cells (H9C2)...
October 15, 2016: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/26716089/serial-elongation-derotation-flexion-casting-for-children-with-early-onset-scoliosis
#20
REVIEW
Federico Canavese, Antoine Samba, Alain Dimeglio, Mounira Mansour, Marie Rousset
Various early-onset spinal deformities, particularly infantile and juvenile scoliosis (JS), still pose challenges to pediatric orthopedic surgeons. The ideal treatment of these deformities has yet to emerge, as both clinicians and surgeons still face multiple challenges including preservation of thoracic motion, spine and cage, and protection of cardiac and lung growth and function. Elongation-derotation-flexion (EDF) casting is a technique that uses a custom-made thoracolumbar cast based on a three-dimensional correction concept...
December 18, 2015: World Journal of Orthopedics
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