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Nguyen Emory

Robert Townsend Cole, Jonathan Gandhi, Robert A Bray, Howard M Gebel, Michael Yin, Nikolaz Shekiladze, An Young, Aubrey Grant, Ian Mahoney, S Raja Laskar, Divya Gupta, Kunal Bhatt, Wendy Book, Andrew Smith, Duc Nguyen, J David Vega, Alanna A Morris
BACKGROUND: Despite improvements in outcomes after heart transplantation, black recipients have worse survival compared with non-black recipients. The source of such disparate outcomes remains largely unknown. We hypothesize that a propensity to generate de-novo donor-specific antibodies (dnDSA) and subsequent antibody-mediated rejection (AMR) may account for racial differences in sub-optimal outcomes after heart transplant. In this study we aimed to determine the role of dnDSA and AMR in racial disparities in post-transplant outcomes...
April 2018: Journal of Heart and Lung Transplantation
Emory Hsu, Varun K Phadke, Minh Ly T Nguyen
We describe an HIV-infected patient initiated on combined antiretroviral therapy (cART) who subsequently developed immune restoration disease (IRD) hyperthyroidism-this case represents one of five such patients seen at our center within the past year. Similar to previous reports of hyperthyroidism due to IRD, all of our patients experienced a rapid early recovery in total CD4 count, but developed symptoms of hyperthyroidism on average 3 years (38 months) after beginning cART, which represents a longer time frame than previously reported...
June 2016: AIDS Research and Human Retroviruses
William T Hu, Kelly D Watts, Prashant Tailor, Trung P Nguyen, Jennifer C Howell, Raven C Lee, Nicholas T Seyfried, Marla Gearing, Chadwick M Hales, Allan I Levey, James J Lah, Eva K Lee
INTRODUCTION: CSF levels of established Alzheimer's disease (AD) biomarkers remain stable despite disease progression, and non-amyloid non-tau biomarkers have the potential of informing disease stage and progression. We previously identified complement 3 (C3) to be decreased in AD dementia, but this change was not found by others in earlier AD stages. We hypothesized that levels of C3 and associated factor H (FH) can potentially distinguish between mild cognitive impairment (MCI) and dementia stages of AD, but we also found their levels to be influenced by age and disease status...
February 17, 2016: Acta Neuropathologica Communications
Vanessa Moll, Elrond Y L Teo, David S Grenda, Cindy D Powell, Michael J Connor, Bryce T Gartland, Mary J Zellinger, H Bruce Bray, Christopher A Paciullo, Craig M Kalin, Jean M Wheeler, Duc Q Nguyen, James M Blum
Extracorporeal membrane oxygenation (ECMO) is an established therapy in the management of patients with refractory cardiogenic shock or acute respiratory failure. In this report, we describe the rapid development and implementation of an organized ECMO program at a facility that previously provided ad hoc support. The program provides care for patients within the Emory Healthcare system and throughout the Southeastern United States. From September 2014 to February 2015, 16 patients were treated with either venovenous or venoarterial ECMO with a survival to decannulation of 53...
May 2016: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
Vinod H Thourani, Chun Li, Chandan Devireddy, Hanna A Jensen, Patrick Kilgo, Bradley G Leshnower, Kreton Mavromatis, Eric L Sarin, Tom C Nguyen, Mihir Kanitkar, Robert A Guyton, Peter C Block, Amanda L Maas, Amy Simone, Patricia Keegan, John Merlino, James P Stewart, Stamatios Lerakis, Vasilis Babaliaros
BACKGROUND: Patient characteristics and procedural outcomes from nontransfemoral (non-TF) transcatheter aortic valve replacement (TAVR) in high-risk or inoperable patients with aortic stenosis have been incompletely reported. The purpose of this study was to compare outcomes with non-TF TAVR access techniques including transapical (TA), transaortic (TAo), and transcarotid (TC) TAVR with a balloon-expandable valve. METHODS: A retrospective review was performed of all patients undergoing TA, TAo, and TC TAVR from 2007 to 2013 at Emory University...
March 2015: Annals of Thoracic Surgery
Diana I Simeonova, Ashraf M Attalla, Theresa Nguyen, Emily Stagnaro, Bettina T Knight, W Edward Craighead, Zachary N Stowe, D Jeffrey Newport
OBJECTIVE: There are no published studies examining concurrent associations between temperament and behavior during toddlerhood in offspring of parents with bipolar disorder (OBD), a population at high familial risk for psychopathology. Better understanding of early determinants contributing to well-being or mental illness in this high-risk population has the potential to aid in the identification of problem domains to be targeted clinically, and facilitate the development of early intervention and prevention initiatives for an appropriate subgroup of children at the youngest possible age...
December 2014: Journal of Child and Adolescent Psychopharmacology
Tom C Nguyen, Vasilis C Babaliaros, Seyed Amirhossein Razavi, Patrick D Kilgo, Chandan M Devireddy, Brad G Leshnower, Kreton Mavromatis, Robert A Guyton, Mihir Kanitkar, Stam Lerakis, John Merlino, Edward P Chen, Vinod H Thourani
BACKGROUND: An increasing number of patients with prior coronary artery bypass grafting (CABG) now present with severe aortic stenosis. The proposed benefit of surgical (SAVR) vs transcatheter aortic valve replacement (TAVR) is unknown. The objective of this study was to compare short-term and midterm outcomes of patients undergoing isolated SAVR vs TAVR in those with prior CABG. METHODS: A retrospective analysis was performed of 255 patients who underwent isolated SAVR after prior CABG from January 2002 to February 2013 at Emory University...
October 2014: Annals of Thoracic Surgery
Vinod H Thourani, Seyed Amirhossein Razavi, Tom C Nguyen, Patrick D Kilgo, John D Puskas, Robert A Guyton, Omar M Lattouf, Bradley G Leshnower, Edward P Chen, Eric L Sarin, Michael E Halkos
BACKGROUND: Atherosclerotic disease of the ascending aorta during coronary artery bypass graft surgery (CABG) increases the risk for postoperative stroke. The objective of this study was to examine the incidence of postoperative stroke in CABG utilizing the Heartstring (Maquet Cardiovascular, San Jose, CA) proximal anastomotic device. METHODS: Intraoperative epiaortic ultrasonography was used to grade atherosclerosis in CABG patients at Emory University from April 2003 to December 2012...
June 2014: Annals of Thoracic Surgery
Vinod H Thourani, Rebecca L Gunter, Soumya Neravetla, Peter Block, Robert A Guyton, Patrick Kilgo, Stamatios Lerakis, Chandan Devireddy, Bradley Leshnower, Kreton Mavromatis, James Stewart, Amy Simone, Patricia Keegan, Tom C Nguyen, John Merlino, Vasilis Babaliaros
BACKGROUND: Transcatheter aortic valve replacement (TAVR) is an effective treatment in patients with severe aortic stenosis unsuitable for surgical aortic valve replacement (SAVR). This study evaluated the early experience with the posttrial application of TAVR, with specific focus on non-transfemoral (TF) access. METHODS: All patients who underwent posttrial TAVR at Emory University from November 2011 to April 2012 were reviewed. During this time, 44 posttrial TAVRs were performed: TF in 18, transapical in 11, transaortic in 12, and transcarotid inĀ 3...
October 2013: Annals of Thoracic Surgery
Amrou Sarraj, Karen Albright, Andrew D Barreto, Amelia K Boehme, Clark W Sitton, Jeanie Choi, Steven L Lutzker, Chung-Huan J Sun, Wafi Bibars, Claude B Nguyen, Osman Mir, Farhaan Vahidy, Tzu-Ching Wu, George A Lopez, Nicole R Gonzales, Randall Edgell, Sheryl Martin-Schild, Hen Hallevi, Peng Roc Chen, Mark Dannenbaum, Jeffrey L Saver, David S Liebeskind, Raul G Nogueira, Rishi Gupta, James C Grotta, Sean I Savitz
BACKGROUND AND PURPOSE: Intra-arterial therapy (IAT) promotes recanalization of large artery occlusions in acute ischemic stroke. Despite high recanalization rates, poor clinical outcomes are common. We attempted to optimize a score that combines clinical and imaging variables to more accurately predict poor outcome after IAT in anterior circulation occlusions. METHODS: Patients with acute ischemic stroke undergoing IAT at University of Texas (UT) Houston for large artery occlusions (middle cerebral artery or internal carotid artery) were reviewed...
December 2013: Stroke; a Journal of Cerebral Circulation
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