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https://www.readbyqxmd.com/read/29340773/feature-codes-in-implicit-sequence-learning-perceived-stimulus-locations-transfer-to-motor-response-locations
#1
Hilde Haider, Sarah Esser, Katharina Eberhardt
An important question in implicit sequence learning research is how the learned information is represented. In earlier models, the representations underlying implicit learning were viewed as being either purely motor or perceptual. These different conceptions were later integrated by multidimensional models such as the Dual System Model of Keele et al. (Psychol Rev 110(2):316-339, 2003). According to this model, different types of sequential information can be learned in parallel, as long as each sequence comprised only one single dimension (e...
January 16, 2018: Psychological Research
https://www.readbyqxmd.com/read/29325975/procedural-outcomes-and-long-term-survival-associated-with-lead-extraction-in-patients-with-abandoned-leads
#2
Faisal M Merchant, Thor Tejada, Adarsh Patel, Jad El-Khalil, Yaanik Desai, Brent Keeling, Omar M Lattouf, Angel R Leon, Mikhael F El-Chami
BACKGROUND: The decision to abandon or extract superfluous sterile leads is controversial. OBJECTIVE: To compare procedural outcomes and long-term survival of patients with and without abandoned leads undergoing lead extraction (LE). METHODS: Retrospective review of all patients undergoing transvenous LE at our institution from Jan. 2007 to May 2016. Patients were stratified into two groups based on the presence (Group 1) or absence (Group 2) of abandoned leads...
January 8, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29322173/association-of-surgical-practice-patterns-and-clinical-outcomes-with-surgeon-training-in-university-or-nonuniversity-based-residency-program
#3
Morgan M Sellers, Luke J Keele, Catherine E Sharoky, Christopher Wirtalla, Elizabeth A Bailey, Rachel R Kelz
Importance: Important metrics of residency program success include the clinical outcomes achieved by trainees after transitioning to practice. Previous studies have shown significant differences in reported training experiences of general surgery residents at nonuniversity-based residency (NUBR) and university-based residency (UBR) programs. Objective: To examine the differences in practice patterns and clinical outcomes between surgeons trained in NUBR and those trained in UBR programs...
January 10, 2018: JAMA Surgery
https://www.readbyqxmd.com/read/29321317/the-wnt-signaling-pathway-is-differentially-expressed-during-the-bovine-herpesvirus-1-latency-reactivation-cycle-evidence-that-two-protein-kinases-associated-with-neuronal-survival-akt3-and-bone-morphogenetic-protein-receptor-2-are-expressed-at-higher-levels
#4
Aspen Workman, Liqian Zhu, Brittney N Keel, Timothy P L Smith, Clinton Jones
Sensory neurons in trigeminal ganglia (TG) of calves latently infected with bovine herpesvirus 1 (BoHV-1) abundantly express latency-related (LR) gene products, including a protein (ORF2) and two micro-RNAs. Recent studies in mouse neuroblastoma cells (Neuro-2A) demonstrated ORF2 interacts with β-catenin and a β-catenin coactivator, high mobility group AT-hook 1 protein (HMGA1), which correlates with increased β-catenin dependent transcription and cell survival. β-catenin and HMGA1 are readily detected in a subset of latently infected TG neurons, but not TG neurons from uninfected calves or reactivation from latency...
January 10, 2018: Journal of Virology
https://www.readbyqxmd.com/read/29318727/transformation-of-diplonema-papillatum-the-type-species-of-the-highly-diverse-and-abundant-marine-micro-eukaryotes-diplonemida-euglenozoa
#5
Binnypreet Kaur, Matus Valach, Priscila Peña-Diaz, Sandrine Moreira, Patrick J Keeling, Gertraud Burger, Julius Lukeš, Drahomíra Faktorová
Diplonema papillatum is the type species of diplonemids, which are among the most abundant and diverse heterotrophic micro-eukaryotes in the world's oceans. Diplonemids are also known for a unique form of post-transcriptional processing in mitochondria. However, the lack of reverse genetics methodologies in these protists has hampered elucidation of their cell and molecular biology. Here we report a protocol for D. papillatum transformation. We have identified several antibiotics to which D. papillatum is sensitive and thus are suitable selectable markers, and focus in particular on puromycin...
January 10, 2018: Environmental Microbiology
https://www.readbyqxmd.com/read/29317656/conservation-of-pattern-as-a-tool-for-inference-on-spatial-snapshots-in-ecological-data
#6
Michael A Irvine, James C Bull, Matt J Keeling
As climate change and other anthropogenic factors increase the uncertainty of vegetation ecosystem persistence, the ability to rapidly assess their dynamics is paramount. Vegetation and sessile communities form a variety of striking regular spatial patterns such as stripes, spots and labyrinths, that have been used as indicators of ecosystem current state, through qualitative analysis of simple models. Here we describe a new method for rigorous quantitative estimation of biological parameters from a single spatial snapshot...
January 9, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29316367/development-of-the-lunate-shaped-caudal-fin-in-white-shark-embryos
#7
Taketeru Tomita, Minoru Toda, Kei Miyamoto, Shin-Ichiro Oka, Keiichi Ueda, Keiichi Sato
The lunate-shaped caudal fin in lamnid sharks is a morphological specialization for their thunniform mode of locomotion, but its developmental process during gestation has been poorly investigated. Observations of 21 embryonic specimens of the white shark (Carcharodon carcharias) revealed that their caudal fin morphology drastically changes from strongly heterocercal to lunate-shaped through ontogeny. This morphological change involves 1) rapid elongation of the ventral lobe, 2) increased upward curvature of the vertebra within the caudal fin, and 3) formation of keels at both lateral sides of the caudal fin base...
January 6, 2018: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/29312617/t-cell-responses-to-kshv-infection-a-systematic-approach
#8
Romin Roshan, Nazzarena Labo, Matthew Trivett, Wendell Miley, Vickie Marshall, Lori Coren, Elena M Cornejo Castro, Hannah Perez, Benjamin Holdridge, Eliza Davis, Rodrigo Matus-Nicodemos, Victor I Ayala, Raymond Sowder, Kathleen M Wyvill, Karen Aleman, Christine Fennessey, Jeffrey Lifson, Mark N Polizzotto, Daniel Douek, Brandon Keele, Thomas S Uldrick, Robert Yarchoan, Claes Ohlen, David Ott, Denise Whitby
Prior studies of T-cell responses to KSHV have included relatively few participants and focused on relatively few KSHV antigens. To provide a more comprehensive analysis, we investigated T-cell responses to the whole KSHV proteome using IFN-γ ELISpot. Using ∼7,500 overlapping 15mer peptides we generated one to three peptide pools for each of the 82 KSHV ORFs. IFN-γ ELISpot analysis of PBMCs from 19 patients with a history of KSHV-associated disease and 24 healthy donors (11 KSHV seropositive) detected widely varied responses...
December 12, 2017: Oncotarget
https://www.readbyqxmd.com/read/29310914/what-can-be-learned-from-an-analysis-of-215-glenoid-component-failures
#9
Jason E Hsu, Daniel J Hackett, Kiet V Vo, Frederick A Matsen
BACKGROUND: Glenoid component failure is a prevalent mechanical complication of anatomic total shoulder arthroplasty. The objective of this study was to identify surgeon-controlled factors that may be addressed to reduce the rate of glenoid component failure that is sufficiently symptomatic to merit surgical revision. METHODS: We reviewed the clinical and radiographic features of 215 total shoulder arthroplasties that we revised for symptomatic glenoid component failure...
January 5, 2018: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/29307097/robotic-inguinal-lymph-node-dissection-for-melanoma-a-novel-approach-to-a-complicated-problem
#10
G Alan Hyde, Nathan L Jung, Alvaro A Valle, Syamal D Bhattacharya, Christopher E Keel
BACKGROUND: Indications for superficial inguinal lymph node (ILN) dissection in melanoma include fine needle aspiration or clinically positive ILN and sentinel lymph nodes (SLN). Open inguinal lymphadenectomy may be complicated by poor wound healing, deep vein thrombosis, and lymphedema. Technical considerations and case series of a novel surgical approach, robotic inguinal lymphadenectomy, are presented. METHODS: This is a case series of four robotic ILN dissections for melanoma at a tertiary care facility...
January 6, 2018: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/29304324/stockings-to-prevent-post-thrombotic-syndrome-where-are-we-now
#11
David Keeling
No abstract text is available yet for this article.
January 2018: Lancet Haematology
https://www.readbyqxmd.com/read/29301766/population-based-assessment-of-visual-acuity-outcomes-following-cataract-surgery-in-australia-the-national-eye-health-survey
#12
Stuart Keel, Jing Xie, Joshua Foreman, Hugh R Taylor, Mohamed Dirani
AIM: To assess the visual outcomes of cataract surgery among a national sample of non-Indigenous and Indigenous Australians. METHODS: This was a population-based study of 3098 non-Indigenous Australians (50-98 years) and 1738 Indigenous Australians (40-92 years), stratified by remoteness. A poor postoperative outcome in an eye that had undergone cataract surgery was defined as presenting distance visual acuity (PVA) <6/12-6/60, and a very poor outcome was defined as PVA <6/60...
January 4, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29288138/phenotypic-plasticity-of-six-unusual-cercariae-in-nassariid-gastropods-and-their-relationships-to-the-acanthocolpidae-and-brachycladiidae-digenea
#13
Leonie J Barnett, Terrence L Miller
Species-level relationships of a complex of six putative acanthocolpid cercariae with ventral keels from nassariid gastropods from Capricornia, Queensland (Cercaria capricornia I-VI) were explored using mitochondrial and nuclear DNA sequence data. Analysis of the large subunit of nuclear ribosomal DNA (rDNA), the internal transcribed spacer 2 rDNA and subunit 3 of the nicotinamide-adenine-dinucleotide dehydrogenase mitochondrial gene indicates that the six distinct morphotypes previously identified relate to only three discrete genotypes...
December 26, 2017: Parasitology International
https://www.readbyqxmd.com/read/29283616/attachment-informed-mentorship
#14
Randall Reitz, Stephen Mitchell, Shannon Keel
Attachment theory has been widely integrated into how clinicians view personal development and enduring relationships. Through the burgeoning field of interpersonal neurobiology, this model has also been applied to adult professional, training, and family relationships. However, the medical and integrated care literature currently lacks attempts to apply attachment principles to the mentorship relationships that are created between trainees and the faculty of a training program. Through this conceptual article, the authors introduce the attachment-informed mentorship model to bridge this gap...
December 2017: Families, Systems & Health: the Journal of Collaborative Family Healthcare
https://www.readbyqxmd.com/read/29276017/evaluation-of-the-effect-of-the-herpes-zoster-vaccination-programme-3-years-after-its-introduction-in-england-a-population-based-study
#15
Gayatri Amirthalingam, Nick Andrews, Philip Keel, David Mullett, Ana Correa, Simon de Lusignan, Mary Ramsay
BACKGROUND: In 2013, a herpes zoster vaccination programme was introduced in England for adults aged 70 years with a phased catch-up programme for those aged 71-79 years. We aimed to evaluate the effect of the first 3 years of the vaccination programme on incidence of herpes zoster and postherpetic neuralgia in this population. METHODS: In this population-based study, we extracted data from the Royal College of General Practitioners sentinel primary care network on consultations with patients aged 60-89 years for herpes zoster and postherpetic neuralgia occurring between Oct 1, 2005, and Sept 30, 2016, obtaining data from 164 practices...
December 21, 2017: Lancet. Public Health
https://www.readbyqxmd.com/read/29275932/an-in-vitro-study-to-assess-the-feasibility-validity-and-precision-of-capturing-oncology-facial-defects-with-multimodal-image-fusion
#16
Rachael Y Jablonski, Cecilie A Osnes, Balvinder S Khambay, Brian R Nattress, Andrew J Keeling
AIM: Assess the feasibility, validity and precision of multimodal image fusion to capture oncology facial defects based on plaster casts. METHODS: Ten casts of oncology facial defects were acquired. To create gold standard models, a 3D volumetric scan of each cast was obtained with a cone beam computed tomography (CBCT) scanner (NewTomVG). This was converted into surface data using open-source medical segmentation software and cropped to produce a CBCT mask using an open-source system for editing meshes...
December 21, 2017: Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
https://www.readbyqxmd.com/read/29275115/results-of-cemented-vs-cementless-primary-total-knee-arthroplasty-using-the-same-implant-design
#17
Adam J Miller, Jeffrey D Stimac, Langan S Smith, Anthony W Feher, Madhusudhan R Yakkanti, Arthur L Malkani
BACKGROUND: Although cemented total knee arthroplasty (TKA) continues to be the gold standard, there are patient populations with higher failure rates with cemented TKAs such as the obese, morbidly obese, and younger active males. Cementless TKA usage continues to increase because of the potential benefits of long-term biologic fixation similar to the rise in cementless total hip arthroplasty. The purpose of this study was to evaluate the clinical and radiographic results of cementless TKA using a novel highly porous cementless tibial baseplate...
December 2, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29261180/preemptive-pharmacogenetic-testing-exploring-the-knowledge-and-perspectives-of-us-payers
#18
Nicholas J Keeling, Meagen M Rosenthal, Donna West-Strum, Amit S Patel, Cyrine E Haidar, James M Hoffman
PurposePreemptive pharmacogenetic testing aims to optimize medication use by having genetic information at the point of prescribing. Payers' decisions influence implementation of this technology. We investigated US payers' knowledge, awareness, and perspectives on preemptive pharmacogenetic testing.MethodsA qualitative study was conducted using semistructured interviews. Participants were screened for eligibility through an online survey. A blended inductive and deductive approach was used to analyze the transcripts...
October 26, 2017: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/29250009/links-between-an-owner-s-adult-attachment-style-and-the-support-seeking-behavior-of-their-dog
#19
Therese Rehn, Andrea Beetz, Linda J Keeling
The aim of this study was to investigate if an owner's adult attachment style (AAS) influences how their dog interacts and obtains support from them during challenging events. A person's AAS describes how they perceive their relationship to other people, but it may also reflect their caregiving behavior, and so their behavior toward the dog. We measured the AAS of 51 female Golden retriever owners, using the Adult Attachment Style Questionnaire (ASQ), and observed the reactions of the dog-owner dyads in response to different challenging situations [visual surprise, auditory stressor and social stressors like a person approaching dressed as ghost or in coat, hat and sunglasses]...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29245711/a-new-species-of-the-genus-i-takydromus-i-squamata-lacertidae-from-tianjingshan-forestry-station-northern-guangdong-china
#20
Ying-Yong Wang, Shi-Ping Gong, Peng Liu, Xin Wang
Many early descriptions of species of the genus Takydromus were based on limited diagnostic characteristics. This has caused considerable challenges in accurate species identification, meaning that a number of cryptic species have been erroneously identified as known species, resulting in substantially underestimated species diversity. We have integrated evidence from morphology and DNA sequence data to describe a new species of the Asian Grass Lizard, Takydromus albomaculosus sp. nov., based on two specimens from Tianjingshan Forestry Station, Ruyuan County, Guangdong Province, China...
October 26, 2017: Zootaxa
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