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https://www.readbyqxmd.com/read/27893503/impacting-care-and-treatment-of-the-burn-patient-conversion-to-electronic-documentation
#1
Holly M Hampe, Terri Keeling, Michelle Fontana, Debbie Balcik
Improving patient care through enhanced electronic communication among health care providers is aimed at reducing the number of medication and medical errors. The American Reinvestment and Recovery Act (ARRA) was signed into law in 2009, supporting the federal government's commitment to the improvement of health care quality, safety, and efficiency through requirements to implement an electronic health record by October 2015 or hospitals and eligible providers potentially realizing penalties or reduced reimbursement rates...
January 2017: Critical Care Nursing Quarterly
https://www.readbyqxmd.com/read/27881551/comparison-of-the-otto-bock-solid-ankle-cushion-heel-foot-with-wooden-keel-to-the-low-cost-cr-equipements%C3%A2-solid-ankle-cushion-heel-foot-with-polypropylene-keel-a-randomized-prospective-double-blind-crossover-study-assessing-patient-satisfaction-and-energy
#2
Alain Lacraz, Stéphane Armand, Katia Turcot, Gorki Carmona, Richard Stern, Olivier Borens, Mathieu Assal
BACKGROUND: The International Committee of the Red Cross supports a worldwide program of prosthetic fitting and rehabilitation. In this context, a prosthetic foot was developed and widely distributed in least developed countries. STUDY DESIGN: Prospective, randomized, double-blind, controlled study. OBJECTIVE: To compare patient satisfaction and energy expenditure during ambulation between a low-cost prosthetic foot designed with a polypropylene keel (CR-Equipements(™) solid ankle cushion heel, International Committee of the Red Cross) to a well-recognized solid ankle cushion heel foot with a wooden keel (solid ankle cushion heel foot, Otto Bock)...
November 22, 2016: Prosthetics and Orthotics International
https://www.readbyqxmd.com/read/27876420/hereditary-bilateral-genu-recurvatum-case-report-of-a-family
#3
Peter Feczko, Pieter Emans
BACKGROUND: Genu recurvatum is a rare condition in children and adolescents. The origin can be osseous, ligamentous and mixed. METHODS: We describe for the first time a family inclusive two brothers and their mother with hereditary bilateral genu recurvatum of unknown etiology. The possible underlying pathology and treatment are discussed. RESULTS: The underlying pathology of the early closure of the apophysis of the tibial tuberosity remained unclear...
November 19, 2016: Knee
https://www.readbyqxmd.com/read/27875688/morphological-identification-and-single-cell-genomics-of-marine-diplonemids
#4
Ryan M R Gawryluk, Javier Del Campo, Noriko Okamoto, Jürgen F H Strassert, Julius Lukeš, Thomas A Richards, Alexandra Z Worden, Alyson E Santoro, Patrick J Keeling
Recent global surveys of marine biodiversity have revealed that a group of organisms known as "marine diplonemids" constitutes one of the most abundant and diverse planktonic lineages [1]. Though discovered over a decade ago [2, 3], their potential importance was unrecognized, and our knowledge remains restricted to a single gene amplified from environmental DNA, the 18S rRNA gene (small subunit [SSU]). Here, we use single-cell genomics (SCG) and microscopy to characterize ten marine diplonemids, isolated from a range of depths in the eastern North Pacific Ocean...
November 21, 2016: Current Biology: CB
https://www.readbyqxmd.com/read/27866818/the-discovery-of-quinoline-based-single-ligand-human-h1-and-h3-receptor-antagonists
#5
Panayiotis A Procopiou, Rachael A Ancliff, Paul M Gore, Ashley P Hancock, Simon T Hodgson, Duncan S Holmes, Steven P Keeling, Brian E Looker, Nigel A Parr, James E Rowedder, Robert J Slack
A novel series of potent quinoline-based human H1 and H3 bivalent histamine receptor antagonists, suitable for intranasal administration for the potential treatment of allergic rhinitis associated nasal congestion, were identified. Compound 18b had slightly lower H1 potency (pA2 8.8 vs 9.7 for the clinical goldstandard azelastine), and H3 potency (pKi 9.1vs 6.8 for azelastine), better selectivity over α1A, α1B and hERG, similar duration of action, making 18b a good back-up compound to our previous candidate, but with a more desirable profile...
December 15, 2016: Bioorganic & Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/27864856/capturing-differences-in-dental-training-using-a-virtual-reality-simulator
#6
I Mirghani, F Mushtaq, M J Allsop, L M Al-Saud, N Tickhill, C Potter, A Keeling, M A Mon-Williams, M Manogue
Virtual reality simulators are becoming increasingly popular in dental schools across the world. But to what extent do these systems reflect actual dental ability? Addressing this question of construct validity is a fundamental step that is necessary before these systems can be fully integrated into a dental school's curriculum. In this study, we examined the sensitivity of the Simodont (a haptic virtual reality dental simulator) to differences in dental training experience. Two hundred and eighty-nine participants, with 1 (n = 92), 3 (n = 79), 4 (n = 57) and 5 (n = 61) years of dental training, performed a series of tasks upon their first exposure to the simulator...
November 19, 2016: European Journal of Dental Education: Official Journal of the Association for Dental Education in Europe
https://www.readbyqxmd.com/read/27859111/the-effect-of-spatial-scale-on-relative-influences-of-assembly-processes-in-temperate-stream-fish-assemblages
#7
Aaron D Geheber, Philip Keel Geheber
Understanding how biotic and abiotic processes influence community assembly is a fundamental aim in ecology. Although spatial scales at which communities are studied may affect the relative importance of such assembly processes, spatial influences on community assembly have not been thoroughly addressed. We tested how spatial scale affects inferences of habitat filtering and competitive exclusion assembly processes in darter (Percidae: Etheostomatinae) assemblages across four temperate stream systems. We predicted competitive exclusion would influence assembly in fine-scale assemblages, and habitat filtering would be more influential as spatial scale increased...
October 2016: Ecology
https://www.readbyqxmd.com/read/27858400/optimisation-of-bmp-2-dosage-for-the-osseointegration-of-porous-titanium-implants-in-an-ovine-model
#8
E B Hunziker, J Jovanovic, A Horner, M J Keel, K Lippuner, N Shintani
In clinical orthopaedics, total joint replacements and spinal fusions are routine undertakings. Many of the implicated patients suffer from osteoporosis, severe arthrosis or osteopaenia. In individuals thus afflicted, the bony bed lacks the mechanical stability that is a requisite for a firm anchorage of the implant and its functional competence. To promote the bony bondage of an implant it is necessary to induce neo-ossification by the introduction of an osteogenic agent, such as bone morphogenetic protein 2 (BMP-2)...
November 18, 2016: European Cells & Materials
https://www.readbyqxmd.com/read/27833419/description-of-rhodnius-marabaensis-sp-n-hemiptera-reduviidae-triatominae-from-par%C3%A3-state-brazil
#9
Eder Dos Santos Souza, Noé Carlos Barbosa Von Atzingen, Maria Betânia Furtado, Jader de Oliveira, Juliana Damieli Nascimento, Daniel Pagotto Vendrami, Sueli Gardim, João Aristeu da Rosa
Rhodnius marabaensissp. n. was collected on 12 May 2014 in the Murumurú Environmental Reserve in the city of Marabá, Pará State, Brazil. This study was based on previous consultation of morphological descriptions of 19 Rhodnius species and compared to the identification key for the genus Rhodnius. The examination included specimens from 18 Rhodnius species held in the Brazilian National and International Triatomine Taxonomy Reference Laboratory in the Oswaldo Cruz Institute in Rio de Janeiro, Brazil. The morphological characteristics of the head, thorax, abdomen, genitalia, and eggs have been determined...
2016: ZooKeys
https://www.readbyqxmd.com/read/27828996/biogeography-and-character-evolution-of-the-ciliate-genus-euplotes-spirotrichea-euplotia-with-description-of-euplotes-curdsi-sp-nov
#10
Mitchell J Syberg-Olsen, Nicholas A T Irwin, Claudia Vannini, Fabrizio Erra, Graziano Di Giuseppe, Vittorio Boscaro, Patrick J Keeling
Ciliates comprise a diverse and ecologically important phylum of unicellular protists. One of the most specious and best-defined genera is Euplotes, which constitutes more than 70 morphospecies, many of which have never been molecularly tested. The increasing number of described Euplotes taxa emphasizes the importance for detailed characterizations of new ones, requiring standardized morphological observations, sequencing of molecular markers and careful comparison with previous literature. Here we describe Euplotes curdsi sp...
2016: PloS One
https://www.readbyqxmd.com/read/27823365/description-of-the-prevalence-histologic-characteristics-concomitant-abnormalities-and-outcomes-of-mammary-gland-tumors-in-companion-rats-rattus-norvegicus-100-cases-1990-2015
#11
Claire Vergneau-Grosset, M Kevin Keel, Dayna Goldsmith, Philip H Kass, Joanne Paul-Murphy, Michelle G Hawkins
OBJECTIVE To describe the prevalence, histologic characteristics, concomitant abnormalities, and outcomes for various types of mammary gland tumors in companion rats (Rattus norvegicus). DESIGN Retrospective case series. ANIMALS 100 client-owned rats. PROCEDURES Medical records of companion rats that had an SC mass and were examined at a veterinary teaching hospital between 1990 and 2015 were reviewed. Information regarding the signalment, age at mass detection, reproductive sterilization status, histologic diagnosis of the SC mass, location of the initial and all subsequent SC masses, treatments administered, and clinical outcomes was extracted from each record and summarized...
November 15, 2016: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/27821220/outdoor-stocking-density-in-free-range-laying-hens-effects-on-behaviour-and-welfare
#12
D L M Campbell, G N Hinch, J A Downing, C Lee
Free-range laying hen systems are increasing within Australia and research is needed to determine optimal outdoor stocking densities. Six small (n=150 hens) experimental flocks of ISA Brown laying hens were housed with access to ranges simulating one of three outdoor stocking densities with two pen replicates per density: 2000 hens/ha, 10 000 hens/ha or 20 000 hens/ha. Birds were provided daily range access from 21 to 36 weeks of age and the range usage of 50% of hens was tracked using radio-frequency identification technology...
November 8, 2016: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/27819513/can-assessment-of-disease-burden-prior-to-changes-in-initial-copd-maintenance-treatment-provide-insight-into-remaining-unmet-needs-a-retrospective-database-study-in-uk-primary-care
#13
Sarah H Landis, Keele Wurst, Hoa Van Le, Kerina Bonar, Yogesh S Punekar
This retrospective cohort study aimed to assess treatment patterns over 24 months amongst patients with chronic obstructive pulmonary disease (COPD), initiating a new COPD maintenance treatment, and to understand clinical indicators of treatment change. Patients included in the study initiated a long-acting β2-agonist (LABA), a long-acting muscarinic antagonist (LAMA), or a combination of LABA and an inhaled corticosteroid (ICS/LABA) between January 1, 2009, and November 30, 2013, as recorded in the United Kingdom Clinical Practice Research Datalink (UK CPRD)...
November 7, 2016: COPD
https://www.readbyqxmd.com/read/27819330/stathmin-like-4-is-critical-for-the-maintenance-of-neural-progenitor-cells-in-dorsal-midbrain-of-zebrafish-larvae
#14
Meng-Ju Lin, Shyh-Jye Lee
A delicate balance between proliferating and differentiating signals is necessary to ensure proper growth and neuronal specification. By studying the developing zebrafish brain, we observed a specific and dynamic expression of a microtubule destabilizer gene, stathmin-like 4 (stmn4), in the dorsal midbrain region. The expression of stmn4 was mutually exclusive to a pan-neuronal marker, elavl3 that indicates its role in regulating neurogenesis. We showed the knockdown or overexpression of stmn4 resulted in premature neuronal differentiation in dorsal midbrain...
November 7, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27811745/garra-fluviatilis-a-new-hillstream-fish-species-cypriniformes-cyprinidae-from-the-kwai-noi-river-system-mae-khlong-basin-thailand
#15
Punnatut Kangrang, Ryan J Thoni, Richard L Mayden, F William H Beamish
Garra fluviatilis is a new species described herein from the Kwai Noi, Mae Khlong basin, in the Thong Pha Phum District of Kanchanaburi Province in western Thailand. It is diagnosed by the following combination of morphological characters: well developed upper lip with unculiferous papillae, mottled pigmentation pattern, a pleated papilliferous fold at the junction of the anterolateral lobe and anteromedial fold on the lower lip, 4-5 anal scales, relatively deep body, keeled nape, and a laterally straight anterior margin of the anteromedial fold...
October 17, 2016: Zootaxa
https://www.readbyqxmd.com/read/27808544/weight-suppression-predicts-bulimic-symptoms-at-20-year-follow-up-the-mediating-role-of-drive-for-thinness
#16
Lindsay P Bodell, Tiffany A Brown, Pamela K Keel
Weight suppression predicts the onset and maintenance of bulimic syndromes. Despite this finding, no study has examined psychological mechanisms contributing to these associations using a longitudinal design. Given societal pressures to be thin and an actual history of higher weight, it is possible that greater weight suppression contributes to increased fear of gaining weight and preoccupation with being thin, which increase vulnerability to eating disorders. The present study investigated whether greater drive for thinness mediates associations between weight suppression and bulimic symptoms over long-term follow-up...
November 3, 2016: Journal of Abnormal Psychology
https://www.readbyqxmd.com/read/27807242/evolution-and-cryo-em-capsid-structure-of-a-north-american-bat-adenovirus-and-its-relationship-to-other-mastadenoviruses
#17
Nicole Hackenbrack, Matthew B Rogers, Robert E Ashley, M Kevin Keel, Steven V Kubiski, John A Bryan, Elodie Ghedin, Edward C Holmes, Susan L Hafenstein, Andrew B Allison
: Since the first description of adenoviruses in bats in 2006, a number of micro- and megabat species in Europe, Africa, and Asia have been shown to carry a wide diversity of adenoviruses. Here, we report on the evolutionary, biological, and structural characterization of a novel bat adenovirus (BtAdV 250-A) recovered from a Rafinesque's big-eared bat (Corynorhinus rafinesquii) in Kentucky, USA, which is the first adenovirus isolated from North American bats. BtAdV 250-A exhibits a close phylogenetic relationship with Canine mastadenovirus A (CAdV A), as previously observed with other BtAdVs...
November 2, 2016: Journal of Virology
https://www.readbyqxmd.com/read/27792892/preserving-privacy-whilst-maintaining-robust-epidemiological-predictions
#18
Marleen Werkman, Michael J Tildesley, Ellen Brooks-Pollock, Matt J Keeling
Mathematical models are invaluable tools for quantifying potential epidemics and devising optimal control strategies in case of an outbreak. State-of-the-art models increasingly require detailed individual farm-based and sensitive data, which may not be available due to either lack of capacity for data collection or privacy concerns. However, in many situations, aggregated data are available for use. In this study, we systematically investigate the accuracy of predictions made by mathematical models initialised with varying data aggregations, using the UK 2001 Foot-and-Mouth Disease Epidemic as a case study...
October 13, 2016: Epidemics
https://www.readbyqxmd.com/read/27789972/keele-aches-and-pains-study-protocol-validity-acceptability-and-feasibility-of-the-keele-start-msk-tool-for-subgrouping-musculoskeletal-patients-in-primary-care
#19
Paul Campbell, Jonathan C Hill, Joanne Protheroe, Ebenezer K Afolabi, Martyn Lewis, Ruth Beardmore, Elaine M Hay, Christian D Mallen, Bernadette Bartlam, Benjamin Saunders, Danielle A van der Windt, Sue Jowett, Nadine E Foster, Kate M Dunn
Musculoskeletal conditions represent a considerable burden worldwide, and are predominantly managed in primary care. Evidence suggests that many musculoskeletal conditions share similar prognostic factors. Systematically assessing patient's prognosis and matching treatments based on prognostic subgroups (stratified care) has been shown to be both clinically effective and cost-effective. This study (Keele Aches and Pains Study) aims to refine and examine the validity of a brief questionnaire (Keele STarT MSK tool) designed to enable risk stratification of primary care patients with the five most common musculoskeletal pain presentations...
2016: Journal of Pain Research
https://www.readbyqxmd.com/read/27775157/genome-wide-copy-number-variation-in-the-bovine-genome-detected-using-low-coverage-sequence-of-popular-beef-breeds
#20
B N Keel, J W Keele, W M Snelling
Copy number variations (CNVs) are large insertions, deletions or duplications in the genome that vary between members of a species and are known to affect a wide variety of phenotypic traits. In this study, we identified CNVs in a population of bulls using low coverage next-generation sequence data. First, in order to determine a suitable strategy for CNV detection in our data, we compared the performance of three distinct CNV detection algorithms on benchmark CNV datasets and concluded that using the multiple sample read depth approach was the best method for identifying CNVs in our sequences...
October 24, 2016: Animal Genetics
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