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https://www.readbyqxmd.com/read/28717917/-acute-right-sided-upper-abdominal-pain-in-a-46-year-old-woman
#1
M Bauder, A Fiala, C Klinger, W Kersjes, K Caca
A 46-year-old woman presented with acute abdominal pain in the right upper quadrant. Esophagogastroduodenoscopy revealed a duodenal stenosis within the horizontal part of the duodenum. Based on the findings of abdominal computed tomography (CT), endosonography, Doppler duplex sonography and angiography, the diagnosis of an aneurysm of a branch of the inferior pancreaticoduodenal artery was established. This arterial branch was part of a collateral circulation between the superior mesenteric artery and the proper hepatic artery caused by obturation of the celiac artery...
July 17, 2017: Der Internist
https://www.readbyqxmd.com/read/28610062/two-new-species-of-freshwater-cave-dwelling-crabs-of-the-genus-i-neostrengeria-i-pretzmann-1965-from-colombia-crustacea-decapoda-pseudothelphusidae
#2
Martha R Campos
Two new species of freshwater crabs of the pseudothelphusid genus Neostrengeria Pretzmann, 1965, N. fernandezi n. sp., and N. lassoi n. sp., are described. The genus is endemic to the eastern Andes of Colombia. Neostrengeria fernandezi was collected in Las Cacas cave, Pauna, Boyacá Department and N. lassoi in a stream within Los Aviones cave, La Guadalupe, Santander Department, within the cave as well as in a waterfall outside the cave. With the addition of N. fernandezi and N. lassoi the total number of species of the genus Neostrengeria increases to 27...
March 27, 2017: Zootaxa
https://www.readbyqxmd.com/read/28608741/efficacy-and-safety-of-the-remove-system-for-otsc-%C3%A2-and-ftrd-%C3%A2-clip-removal-data-from-a-pmcf-analysis
#3
Antonio Caputo, Arthur Schmidt, Karel Caca, Peter Bauerfeind, Sebastian Schostek, Chi-Nghia Ho, Thomas Gottwald, Marc O Schurr
INTRODUCTION: The remOVE System (Ovesco Endoscopy AG, Tuebingen, Germany) is a medical device for the endoscopic removal of OTSC or FTRD clips (Ovesco Endoscopy AG, Tuebingen, Germany). The aim of this paper is to assess the efficacy and safety of this system. MATERIAL AND METHODS: A total of 74 patients underwent clip extraction. The standard removal procedure comprises fragmenting the clip by applying an electrical direct current pulse at two opposing sides of the clip...
June 13, 2017: Minimally Invasive Therapy & Allied Technologies: MITAT
https://www.readbyqxmd.com/read/28588877/endoscopic-removal-of-over-the-scope-clips-clinical-experience-with-a-bipolar-cutting-device
#4
Markus Bauder, Benjamin Meier, Karel Caca, Arthur Schmidt
BACKGROUND: Over-the-scope clips (OTSCs) are increasingly used for the closure of perforations/fistulae, hemostasis and endoscopic full-thickness resection (FTRD system). When OTSC-associated complications occur or re-therapy at the OTSC site is needed, OTSC removal may be indicated. An experimental study in an animal model and a case series have shown good results for OTSC removal with a bipolar cutting device. We present a larger clinical study using this device. METHODS: Data of all consecutive patients with indication for OTSC removal were collected and analyzed retrospectively...
June 2017: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/28507752/effective-treatment-of-benign-biliary-strictures-with-a-removable-fully-covered-self-expandable-metal-stent-a-prospective-multicenter-european-study
#5
Arthur Schmidt, Tilman Pickartz, Markus M Lerch, Fabrizio Fanelli, Fausto Fiocca, Pierleone Lucatelli, Fabrizio Cereatti, Albrecht Hoffmeister, Werner van Steenbergen, Matthias Kraft, Benjamin Meier, Karel Caca
BACKGROUND: Temporary placement of removable, fully covered, self-expandable metal stents (fcSEMS) for treatment of benign biliary strictures (BBS) has been reported to be effective. However, the optimal extraction time point remains unclear and stent migration has been a major concern. OBJECTIVE: The objective of this study was to evaluate the efficacy and safety of this treatment modality using an fcSEMS with a special antimigration design and prolonged stent indwell time...
April 2017: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/28431114/molecular-characterization-of-cryptococcus-neoformans-isolated-from-the-environment-in-beijing-china
#6
Hongtao Dou, Huizhu Wang, Shaowei Xie, Xinxin Chen, Zhipeng Xu, Yingchun Xu
The molecular type of environmental Cryptococcus neoformans in Beijing was not clear. Our study aims to reveal the molecular characterization of C. neoformans complex from environment in Beijing, China. A total of 435 samples of pigeon droppings from 11 different homes in Beijing were collected from August to November in 2015. Pigeon droppings were inoculated onto caffeic acid cornmeal agar (CACA) to screen C. neoformans complex. Bruker Biotyper matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) was performed for species identification...
April 20, 2017: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/28281119/hybrid-endoscopic-mucosal-resection-and-full-thickness-resection-a-new-approach-for-resection-of-large-non-lifting-colorectal-adenomas-with-video
#7
Benjamin Meier, Karel Caca, Arthur Schmidt
BACKGROUND: Clip-assisted endoscopic full-thickness resection (EFTR) with an over-the-scope device has been recently described to be feasible and effective for the resection of non-lifting adenomas in the lower gastrointestinal tract. However, tumor size is the major limitation of that technique. We describe a hybrid technique using endoscopic mucosal resection (EMR) in ten patients with large non-lifting colorectal adenomas to reduce tumor size and facilitate clip-assisted EFTR. METHODS: Data of ten consecutive patients (median age 72...
March 9, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28229075/endoscopic-and-photodynamic-therapy-of-cholangiocarcinoma
#8
REVIEW
Benjamin Meier, Karel Caca
BACKGROUND: Most patients with cholangiocarcinoma (CCA) have unresectable disease. Endoscopic bile duct drainage is one of the major objectives of palliation of obstructive jaundice. METHODS/RESULTS: Stent implantation using endoscopic retrograde cholangiography is considered to be the standard technique. Unilateral versus bilateral stenting is associated with different advantages and disadvantages; however, a standard approach is still not defined. As there are various kinds of stents, there is an ongoing discussion on which stent to use in which situation...
December 2016: Visceral Medicine
https://www.readbyqxmd.com/read/28138791/effect-of-pulse-polarity-on-thresholds-and-on-non-monotonic-loudness-growth-in-cochlear-implant-users
#9
Olivier Macherey, Robert P Carlyon, Jacques Chatron, Stéphane Roman
Most cochlear implants (CIs) activate their electrodes non-simultaneously in order to eliminate electrical field interactions. However, the membrane of auditory nerve fibers needs time to return to its resting state, causing the probability of firing to a pulse to be affected by previous pulses. Here, we provide new evidence on the effect of pulse polarity and current level on these interactions. In experiment 1, detection thresholds and most comfortable levels (MCLs) were measured in CI users for 100-Hz pulse trains consisting of two consecutive biphasic pulses of the same or of opposite polarity...
June 2017: Journal of the Association for Research in Otolaryngology: JARO
https://www.readbyqxmd.com/read/27965686/ca-2-cation-antiporters-caca-identification-characterization-and-expression-profiling-in-bread-wheat-triticum-aestivum-l
#10
Mehak Taneja, Shivi Tyagi, Shailesh Sharma, Santosh Kumar Upadhyay
The Ca(2+)/cation antiporters (CaCA) superfamily proteins play vital function in Ca(2+) ion homeostasis, which is an important event during development and defense response. Molecular characterization of these proteins has been performed in certain plants, but they are still not characterized in Triticum aestivum (bread wheat). Herein, we identified 34 TaCaCA superfamily proteins, which were classified into TaCAX, TaCCX, TaNCL, and TaMHX protein families based on their structural organization and evolutionary relation with earlier reported proteins...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27863711/n-acylated-chitosan-bis-arylcarbamate-s-a-class-of-promising-chiral-separation-materials-with-powerful-enantioseparation-capability-and-high-eluents-tolerability
#11
Sheng Tang, Jian-De Liu, Qin Bin, Ke-Qin Fu, Xiao-Chen Wang, Ying-Bin Luo, Shao-Hua Huang, Zheng-Wu Bai
In order to comprehensively understand the influence of coordination of the substituent at 2-position with those at 3- and 6-positions on the properties of chitosan derivatives, a series of chitosan 3,6-bis(arylcarbamate)-2-(amide)s (CACAs) and the related chiral stationary phases (CSPs) were prepared and reported in the present study. Specifically, chitosan was N-acylated with carboxylic acid anhydrides, and then further derivatized with various aryl isocyanates to afford CACAs, from which a class of coated-type CSPs were prepared...
December 9, 2016: Journal of Chromatography. A
https://www.readbyqxmd.com/read/27803703/how-very-long-chain-fatty-acids-could-signal-stressful-conditions-in-plants
#12
Antoine De Bigault Du Granrut, Jean-Luc Cacas
Although encountered in minor amounts in plant cells, very-long-chain fatty acids exert crucial functions in developmental processes. When their levels are perturbed by means of genetic approaches, marked phenotypic consequences that range from severe growth retardation to embryo lethality was indeed reported. More recently, a growing body of findings has also accumulated that points to a potential role for these lipids as signals in governing both biotic and abiotic stress outcomes. In the present work, we discuss the latter theory and explore the ins and outs of very-long-chain fatty acid-based signaling in response to stress, with an attempt to reconcile two supposedly antagonistic parameters: the insoluble nature of fatty acids and their signaling function...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27778440/antithrombotic-treatment-with-direct-acting-oral-anticoagulants-in-patients-with-splanchnic-vein-thrombosis-and-cirrhosis
#13
Andrea De Gottardi, Jonel Trebicka, Christoph Klinger, Aurélie Plessier, Susana Seijo, Benedetta Terziroli, Lorenzo Magenta, David Semela, Elisabetta Buscarini, Philippe Langlet, Jan Görtzen, Angela Puente, Beat Müllhaupt, Carmen Navascuès, Filipe Nery, Pierre Deltenre, Fanny Turon, Cornelius Engelmann, Rupen Arya, Karel Caca, Markus Peck-Radosavljevic, Frank W G Leebeek, Dominique Valla, Juan Carlos Garcia-Pagan
BACKGROUND: Direct-acting oral anticoagulants (DOACs) are used in patients with splanchnic vein thrombosis (SVT) and cirrhosis, but evidence for safety and efficacy in this setting is limited. Our aim was to identify indications and reasons for starting or switching to DOACs and to report adverse effects, complications and short-term outcome. METHODS: Data collection including demographic information, laboratory values, treatment and complications through the Vascular Liver Disease Interest Group Consortium...
May 2017: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/27776843/histopathological-regression-after-neoadjuvant-docetaxel-oxaliplatin-fluorouracil-and-leucovorin-versus-epirubicin-cisplatin-and-fluorouracil-or-capecitabine-in-patients-with-resectable-gastric-or-gastro-oesophageal-junction-adenocarcinoma-flot4-aio-results
#14
RANDOMIZED CONTROLLED TRIAL
Salah-Eddin Al-Batran, Ralf D Hofheinz, Claudia Pauligk, Hans-Georg Kopp, Georg Martin Haag, Kim Barbara Luley, Johannes Meiler, Nils Homann, Sylvie Lorenzen, Harald Schmalenberg, Stephan Probst, Michael Koenigsmann, Matthias Egger, Nicole Prasnikar, Karel Caca, Jörg Trojan, Uwe M Martens, Andreas Block, Wolfgang Fischbach, Rolf Mahlberg, Michael Clemens, Gerald Illerhaus, Katja Zirlik, Dirk M Behringer, Wolff Schmiegel, Michael Pohl, Michael Heike, Ulrich Ronellenfitsch, Martin Schuler, Wolf O Bechstein, Alfred Königsrainer, Timo Gaiser, Peter Schirmacher, Wael Hozaeel, Alexander Reichart, Thorsten O Goetze, Mark Sievert, Elke Jäger, Stefan Mönig, Andrea Tannapfel
BACKGROUND: Docetaxel-based chemotherapy is effective in metastatic gastric and gastro-oesophageal junction adenocarcinoma, but has not yet been evaluated in the context of resectable patients. Here we report findings from the phase 2 part of the phase 2/3 FLOT4 trial, which compared histopathological regression in patients treated with a docetaxel-based triplet chemotherapy versus an anthracycline-based triplet chemotherapy before surgical resection. METHODS: In this randomised, open-label, phase 2/3 study, eligible participants were recruited from 28 German oncology centres...
December 2016: Lancet Oncology
https://www.readbyqxmd.com/read/27663923/puva-induced-bullous-pemphigoid-in-psoriasis
#15
Nina Caca-Biljanovska, Irina Arsovska-Bezhoska, Marija V'lckova-Laskoska
The association between psoriasis vulgaris and bullous pemphigoid is due to the still unclear autoimmune process. The common disease site is the dermo-epidermal junction or basal membrane zone (BMZ), with specific alterations for both diseases. Photochemotherapy (PUVA) is one of the therapeutic modalities for psoriasis and can trigger production of autoantibodies against antigens in the BMZ in patients with subclinical bullous pemphigoid. Furthermore, PUVA therapy can alter the immunological milieu and hence can contribute to the expression of bullous pemphigoid in patients with psoriasis...
August 2016: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/27581508/in-reply
#16
Arthur Schmidt, Karel Caca
No abstract text is available yet for this article.
August 8, 2016: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/27492731/retina-ganglion-cell-inner-plexiform-layer-and-peripapillary-nerve-fiber-layer-thickness-in-patients-with-acromegaly
#17
Muhammed Şahin, Alparslan Şahin, Faruk Kılınç, Harun Yüksel, Zeynep Gürsel Özkurt, Fatih Mehmet Türkcü, Zafer Pekkolay, Hikmet Soylu, İhsan Çaça
Increased secretion of growth hormone and insulin-like growth factor-1 in acromegaly has various effects on multiple organs. However, the ocular effects of acromegaly have yet to be investigated in detail. The aim of the present study was to compare retina ganglion cell/inner plexiform layer (GCIPL) and peripapillary nerve fiber layer thickness (pRNFL) between patients with acromegaly and healthy control subjects using spectral domain optical coherence tomography (SD-OCT). This cross-sectional, comparative study included 18 patients with acromegaly and 20 control subjects...
August 4, 2016: International Ophthalmology
https://www.readbyqxmd.com/read/27291786/gherf-iib3-regulates-the-accumulation-of-jasmonate-and-leads-to-enhanced-cotton-resistance-to-blight-disease
#18
Jean-Luc Cacas, Martial Pré, Maxime Pizot, Maimouna Cissoko, Issa Diedhiou, Aida Jalloul, Patrick Doumas, Michel Nicole, Antony Champion
The phytohormone jasmonic acid (JA) and its derivatives, collectively referred to as jasmonates, regulate many developmental processes, but are also involved in the response to numerous abiotic/biotic stresses. Thus far, powerful reverse genetic strategies employing perception, signalling or biosynthesis mutants have broadly contributed to our understanding of the role of JA in the plant stress response and development, as has the chemical gain-of-function approach based on exogenous application of the hormone...
June 13, 2016: Molecular Plant Pathology
https://www.readbyqxmd.com/read/27272019/diacylglycerol-kinases-activate-tobacco-nadph-oxidase-dependent-oxidative-burst-in-response-to-cryptogein
#19
Jean-Luc Cacas, Patricia Gerbeau-Pissot, Jérôme Fromentin, Catherine Cantrel, Dominique Thomas, Emmanuelle Jeannette, Tetiana Kalachova, Sébastien Mongrand, Françoise Simon-Plas, Eric Ruelland
Cryptogein is a 10 kDa protein secreted by the oomycete Phytophthora cryptogea that activates defence mechanisms in tobacco plants. Among early signalling events triggered by this microbial-associated molecular pattern is a transient apoplastic oxidative burst which is dependent on the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activity of the RESPIRATORY BURST OXIDASE HOMOLOG isoform D (RBOHD). Using radioactive [(33) P]-orthophosphate labelling of tobacco Bright Yellow-2 suspension cells, we here provide in vivo evidence for a rapid accumulation of phosphatidic acid (PA) in response to cryptogein because of the coordinated onset of phosphoinositide-dependent phospholipase C and diacylglycerol kinase (DGK) activities...
June 6, 2016: Plant, Cell & Environment
https://www.readbyqxmd.com/read/27074617/gipc-glycosyl-inositol-phospho-ceramides-the-major-sphingolipids-on-earth
#20
REVIEW
Julien Gronnier, Véronique Germain, Paul Gouguet, Jean-Luc Cacas, Sébastien Mongrand
What are the most abundant sphingolipids on earth? The answer is Glycosyl Inositol Phosphoryl Ceramides (GIPCs) present in fungi and the green lineage. In this review, we discuss the putative role of plant GIPCs in the lipid bilayer asymmetry, in the lateral organization of membrane rafts and in the very long chain fatty acid inter-leaflet coupling of lipids in the plant plasma membrane (PM). A special focus on the structural similarities -and putative functions- of GIPCs is discussed by comparison with animal gangliosides, structural homologs of plant GIPCs...
2016: Plant Signaling & Behavior
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