Shana Godfred-Cato, Bobbi Bryant, Jessica Leung, Matthew E Oster, Laura Conklin, Joseph Abrams, Katherine Roguski, Bailey Wallace, Emily Prezzato, Emilia H Koumans, Ellen H Lee, Anita Geevarughese, Maura K Lash, Kathleen H Reilly, Wendy P Pulver, Deepam Thomas, Kenneth A Feder, Katherine K Hsu, Nottasorn Plipat, Gillian Richardson, Heather Reid, Sarah Lim, Ann Schmitz, Timmy Pierce, Susan Hrapcak, Deblina Datta, Sapna Bamrah Morris, Kevin Clarke, Ermias Belay
In April 2020, during the peak of the coronavirus disease 2019 (COVID-19) pandemic in Europe, a cluster of children with hyperinflammatory shock with features similar to Kawasaki disease and toxic shock syndrome was reported in England* (1). The patients' signs and symptoms were temporally associated with COVID-19 but presumed to have developed 2-4 weeks after acute COVID-19; all children had serologic evidence of infection with SARS-CoV-2, the virus that causes COVID-19 (1). The clinical signs and symptoms present in this first cluster included fever, rash, conjunctivitis, peripheral edema, gastrointestinal symptoms, shock, and elevated markers of inflammation and cardiac damage (1)...
August 14, 2020: MMWR. Morbidity and Mortality Weekly Report