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https://www.readbyqxmd.com/read/29776736/trabecular-bone-score-at-the-distal-femur-and-proximal-tibia-in-individuals-with-spinal-cord-injury
#1
Stacey Lobos, Anne Cooke, Gillian Simonett, Chester Ho, Steven K Boyd, W Brent Edwards
Rapid declines in bone mineral density (BMD) at the knee after spinal cord injury (SCI) are associated with an increased risk of fracture. Evaluation of bone quality using the trabecular bone score (TBS) may provide a complimentary measure to BMD assessment to examine bone health and fracture risk after SCI. The purpose of this study was to assess bone mineral density (BMD) and trabecular bone score (TBS) at the knee in individuals with and without SCI. Nine individuals with complete SCI (mean time since SCI 2...
April 24, 2018: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/29773425/strain-rate-dependency-of-bovine-trabecular-bone-under-impact-loading-at-sideways-fall-velocity
#2
William S Enns-Bray, Stephen J Ferguson, Benedikt Helgason
There is currently a knowledge gap in scientific literature concerning the strain rate dependent properties of trabecular bone at intermediate strain rates. Meanwhile, strain rates between 10 and 200/s have been observed in previous dynamic finite element models of the proximal femur loaded at realistic sideways fall speeds. This study aimed to quantify the effect of strain rate (ε̇) on modulus of elasticity (E), ultimate stress (σu ), failure energy (Uf ), and minimum stress (σm ) of trabecular bone in order to improve the biofidelity of material properties used in dynamic simulations of sideways fall loading on the hip...
May 3, 2018: Journal of Biomechanics
https://www.readbyqxmd.com/read/29759948/measuring-relative-positions-and-orientations-of-the-tibia-with-respect-to-the-femur-using-one-channel-3d-tracked-a-mode-ultrasound-tracking-system-a-cadaveric-study
#3
Kenan Niu, Jasper Homminga, Victor Sluiter, André Sprengers, Nico Verdonschot
The purpose of this study is to investigate the technical feasibility of measuring relative positions and orientations of the tibia with respect to the femur in an in-vitro experiment by using a 3D-tracked A-mode ultrasound system and to determine its accuracy of angular and translational measurements. As A-mode ultrasound is capable of detecting bone surface through soft tissue in a non-invasive manner, the combination of a single A-mode ultrasound transducer with an optical motion tracking system provides the possibility for digitizing the 3D locations of bony points at different anatomical regions on the thigh and the shank...
May 11, 2018: Medical Engineering & Physics
https://www.readbyqxmd.com/read/29758361/bone-accrual-in-oligo-amenorrheic-athletes-eumenorrheic-athletes-and-non-athletes
#4
Vibha Singhal, Karen Campoverde Reyes, Brooke Pfister, Kathryn Ackerman, Meghan Slattery, Katherine Cooper, Alexander Toth, Nupur Gupta, Mark Goldstein, Kamryn Eddy, Madhusmita Misra
BACKGROUND: Mechanical loading improves bone mineral density (BMD) and strength while decreasing fracture risk. Cross-sectional studies show that exercise advantage is lost in oligo-amenorrheic athletes (OA). Longitudinal studies examining the opposing effects of exercise and hypogonadism on bone are lacking in adolescents/young adults. OBJECTIVE: Evaluate differences in bone accrual over 12 months in OA, eumenorrheic athletes (EA) and non-athletes (NA). We hypothesized that bone accrual would be lower in OA than EA and NA, with differences most pronounced at non-weight bearing trabecular sites...
May 11, 2018: Bone
https://www.readbyqxmd.com/read/29751130/association-of-high-resolution-peripheral-quantitative-computed-tomography-hr-pqct-bone-microarchitectural-parameters-with-previous-clinical-fracture-in-older-men-the-osteoporotic-fractures-in-men-mros-study
#5
Howard A Fink, Lisa Langsetmo, Tien N Vo, Eric S Orwoll, John T Schousboe, Kristine E Ensrud
High-resolution peripheral quantitative computed tomography (HR-pQCT) assesses both volumetric bone mineral density (vBMD) and trabecular and cortical microarchitecture. However, studies of the association of HR-pQCT parameters with fracture history have been small, predominantly limited to postmenopausal women, often performed limited adjustment for potential confounders including for BMD, and infrequently assessed strength or failure measures. We used data from the Osteoporotic Fractures in Men (MrOS) study, a prospective cohort study of community-dwelling men aged ≥65 years, to evaluate the association of distal radius, proximal (diaphyseal) tibia and distal tibia HR-pQCT parameters measured at the Year 14 (Y14) study visit with prior clinical fracture...
May 8, 2018: Bone
https://www.readbyqxmd.com/read/29750848/accelerated-bone-loss-in-older-men-effects-on-bone-microarchitecture-and-strength
#6
J A Cauley, A J Burghardt, S L Harrison, P M Cawthon, A V Schwartz, E Barrett Connor, Kristine E Ensrud, Lisa Langsetmo, S Majumdar, E Orwoll
Accelerated bone loss (ABL) shown on routine dual-energy X-ray absorptiometry (DXA) may be accompanied by microarchitectural changes, increased cortical porosity and lower bone strength. To test this hypothesis, we performed a cross-sectional study and used high resolution peripheral quantitative computed tomography (HR-pQCT) scans (SCANCO, Inc., Switzerland) to measure estimated bone strength and microarchitecture in the distal radius and distal and diaphyseal tibia. We studied 1628 men who attended the Year 14 exam of the Osteoporotic Fractures in Men (MrOS) study...
May 11, 2018: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/29750829/robust-trabecular-microstructure-in-type-2-diabetes-revealed-by-individual-trabecula-segmentation-analysis-of-hr-pqct-images
#7
Jessica F Starr, Leonardo C Bandeira, Sanchita Agarwal, Ankit M Shah, Kyle K Nishiyama, Yizhong Hu, Donald J McMahon, X Edward Guo, Shonni J Silverberg, Mishaela R Rubin
Type 2 diabetes (T2D) patients have an increased fracture risk, which may be partly explained by compromised bone microarchitecture within the cortical bone compartment. Data on trabecular bone parameters in T2D are contradictory. By high resolution peripheral quantitative computed tomography (HR-pQCT) trabecular microarchitecture is preserved, yet larger trabecular holes are detected in T2D by MRI and DXA-based trabecular bone scores (TBS) are abnormal. To determine if there are differences in trabecular microstructure, connectivity and alignment in postmenopausal women with T2D as compared to controls, we performed individual trabecula segmentation (ITS) analysis on high-resolution peripheral quantitative computed tomography (HR-pQCT) scans of the distal radius and tibia in 92 women with (n = 42) and without (n = 50) T2D...
May 11, 2018: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/29737558/risk-of-injury-to-the-sural-nerve-during-posterolateral-approach-to-the-distal-tibia-an-ultrasound-simulation-study
#8
Ewa Mizia, Przemysław A Pękala, Piotr Chomicki-Bindas, Wojciech Marchewka, Marios Loukas, Alexander G Zayachkowski, Krzysztof A Tomaszewski
Introduction When surgeons operate on the foot and ankle, the most common complication that may arise is injury of the cutaneous nerves. The sural nerve (SN) is potentially at risk of being injured when treating fractures involving the distal tibia using the posterolateral approach. The aim of this study was to evaluate how differences in length and position of the surgical treatment of fractures involving the distal tibia can affect the risk of SN injury. Materials and Methods The study involved 40 healthy volunteers (n=80 lower limbs)...
May 8, 2018: Clinical Anatomy
https://www.readbyqxmd.com/read/29737002/lower-limb-reconstruction-with-chimeric-flaps-the-quad-flap
#9
Solomon M Azouz, Nikki A Castel, Aparna Vijayasekaran, Alanna M Rebecca, Salvatore C Lettieri
Early soft-tissue coverage is critical for treating traumatic open lower-extremity wounds. As free-flap reconstruction evolves, injuries once thought to be nonreconstructable are being salvaged. Free-tissue transfer is imperative when there is extensive dead space or exposure of vital structures such as bone, tendon, nerves, or blood vessels. We describe 2 cases of lower-extremity crush injuries salvaged with the quad flap. This novel flap consists of parascapular, scapular, serratus, and latissimus dorsi free flaps in combination on one pedicle...
May 7, 2018: Microsurgery
https://www.readbyqxmd.com/read/29735339/distal-medial-tibial-locking-plate-for-fixation-of-extraarticular-distal-humeral-fractures-an-alternative-choice-for-fixation
#10
Ali Cagdas Yorukoglu, Ahmet Fahir Demirkan, Nihal Buker
OBJECTIVE: The aim of this study was to describe an alternative fixation method for distal humeral extra-articular fractures through posterior approach using distal tibia anatomic locking plate; and to evaluate the patient's functional outcome and union condition. METHODS: Eighteen patients (11 men and 7 women; average age of 37.0 ± 17.3 years (range: 18-73 years)) with a distal humeral extra-articular fracture who were treated with distal tibial medial locking plate were included into the study...
May 4, 2018: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/29732517/coronal-tibiofemoral-subluxation-is-correlated-to-correction-angle-in-medial-opening-wedge-high-tibial-osteotomy
#11
Hiroyasu Ogawa, Kazu Matsumoto, Haruhiko Akiyama
PURPOSE: This study aimed to analyse the change in coronal tibiofemoral (CTF) subluxation after high tibial osteotomy and to determine demographic variables associated with CTF subluxation. The change in CTF subluxation was hypothesised to be associated with the magnitude of correction of lower limb alignment and medial proximal tibial angle (MPTA). METHODS: A total of 103 consecutive knees in 86 patients who underwent medial opening wedge high tibial osteotomy for symptomatic medial compartment knee osteoarthritis were retrospectively analysed...
May 7, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29730704/normal-bone-microstructure-and-density-but-worse-physical-function-in-older-women-treated-with-selective-serotonin-reuptake-inhibitors-a-cross-sectional-population-based-study
#12
Berit Larsson, Dan Mellström, Lisa Johansson, Anna G Nilsson, Mattias Lorentzon, Daniel Sundh
Depression in the elderly is today often treated with selective serotonin reuptake inhibitors (SSRIs) because of their favorable adverse effect profile. However, treatment with SSRIs is associated with increased risk of fractures. Whether this increased risk depends on reduced bone strength or increased fall risk due to reduced physical function is not certain. The aim was therefore to investigate if treatment with SSRIs is associated with impaired bone microstructure, bone density, or physical function in older women...
May 5, 2018: Calcified Tissue International
https://www.readbyqxmd.com/read/29725715/fermented-dairy-products-consumption-is-associated-with-attenuated-cortical-bone-loss-independently-of-total-calcium-protein-and-energy-intakes-in-healthy-postmenopausal-women
#13
E Biver, C Durosier-Izart, F Merminod, T Chevalley, B van Rietbergen, S L Ferrari, R Rizzoli
A longitudinal analysis of bone microstructure in postmenopausal women of the Geneva Retirees Cohort indicates that age-related cortical bone loss is attenuated at non-bearing bone sites in fermented dairy products consumers, not in milk or ripened cheese consumers, independently of total energy, calcium, or protein intakes. INTRODUCTION: Fermented dairy products (FDP), including yogurts, provide calcium, phosphorus, and proteins together with prebiotics and probiotics, all being potentially beneficial for bone...
May 3, 2018: Osteoporosis International
https://www.readbyqxmd.com/read/29721809/gushukang-exerts-osteopreserve-effects-by-regulating-vitamin-d-and-calcium-metabolism-in-ovariectomized-mice
#14
Xiao-Li Li, Liang Wang, Xiao-Lei Bi, Bing-Bing Chen, Yan Zhang
Calcium homeostasis plays vital roles in the management of bone health. Traditional herbal formula Gushukang (GSK) was clinically applied to treat primary osteoporosis. This study aimed to explore the osteoprotective effects of GSK and its roles in maintaining calcium homeostasis in ovariectomized (OVX) mice. The OVX mice were orally treated with low (0.38 g/kg), middle (0.76 g/kg) and high (1.52 g/kg) dose of GSK for 8 weeks. GSK treatment dramatically increased serum calcium level and decreased urinary calcium excretion as well as enhanced calcium content in bone of OVX mice...
May 2, 2018: Journal of Bone and Mineral Metabolism
https://www.readbyqxmd.com/read/29716532/limb-saving-surgery-for-ewing-s-sarcoma-of-the-distal-tibia-a-case-report
#15
Naoki Mizoshiri, Toshiharu Shirai, Ryu Terauchi, Shinji Tsuchida, Yuki Mori, Yusei Katsuyama, Daichi Hayashi, Yoshinobu Oka, Toshikazu Kubo
BACKGROUND: Ewing's sarcoma is a primary malignant tumor of bone occurring mostly in childhood. Few effective reconstruction techniques are available after wide resection of Ewing's sarcoma at the distal end of the tibia. Reconstruction after wide resection is especially difficult in children, as it is necessary to consider the growth and activity of the lower limbs. CASE PRESENTATION: A 12-year-old Japanese boy had presented with right lower leg pain at age 8 years...
May 2, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29710663/effect-of-zuoguiwan-on-osteoporosis-in-ovariectomized-rats-through-rankl-opg-pathway-mediated-by-%C3%AE-2ar
#16
Feixiang Liu, Feng Tan, Weiwei Tong, Qiaoling Fan, Sumin Ye, Shengfeng Lu, Zhanli Teng, Miaomiao Han, Mingyue Zhang, Yi Chai
ETHNOPHARMACOLOGICAL RELEVANCE: The deficiency of kidney Yin is the main pathogenesis of postmenopausal osteoporosis (PMOP) according to traditional Chinese medicine (TCM). Zuoguiwan (ZGW) is among the classical prescriptions in TCM and has been applied to various diseases that are due to deficiency of kidney Yin, including osteoporosis, fractures, menopausal syndromes. However, the underlying mechanism of ZGW in treating PMOP remains poorly understood. AIM OF THE STUDY: ZGW, a traditional Chinese prescription, has been used to nourish Yin and reinforce the kidney since ancient times...
April 25, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29709620/changes-in-tibial-bone-microarchitecture-in-female-recruits-in-response-to-8-weeks-of-u-s-army-basic-combat-training
#17
Julie M Hughes, Erin Gaffney-Stomberg, Katelyn I Guerriere, Kathryn M Taylor, Kristin L Popp, Chun Xu, Ginu Unnikrishnan, Jeffery S Staab, Ronald W Matheny, James P McClung, Jaques Reifman, Mary L Bouxsein
BACKGROUND: U.S. Army Basic Combat Training (BCT) is a physically-demanding program at the start of military service. Whereas animal studies have shown that increased mechanical loading rapidly alters bone structure, there is limited evidence of changes in bone density and structure in humans exposed to a brief period of unaccustomed physical activity. PURPOSE: We aimed to characterize changes in tibial bone density and microarchitecture and serum-based biochemical markers of bone metabolism in female recruits as a result of 8 weeks of BCT...
April 27, 2018: Bone
https://www.readbyqxmd.com/read/29703017/osteochondroma-of-ventral-scapula-associated-with-chest-pain-due-to-rib-cage-compression-a-case-report
#18
Dong-Il Chun, Jae-Ho Cho, In Ho Choi, Young Yi, Jun Yong Kim, Jae Heon Kim, Sung Hun Won
RATIONALE: The scapula is relatively rare site for osteochondroma. Scapula osteochondroma is usually asymptomatic, however it may present with features such as pseudowinging, snapping scapula, bursa formation, chronic pain, and cosmetic deformities. To our best knowledge, this is the first report in the English literature about osteochondroma of ventral scapula associated with chest pain due to rib cage compression. PATIENT CONCERNS: A 14-year-old boy was transferred to the orthopedic clinic from thoracic surgery department with a complaint of intermittent, dull, and diffuse aching pain around left chest wall and back from the past 2 months...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29701099/management-of-extra-articular-segmental-defects-in-long-bone-using-a-titanium-mesh-cage-as-an-adjunct-to-other-methods-of-fixation
#19
N Attias, A M Thabet, G Prabhakar, J A Dollahite, R J Gehlert, T A DeCoster
Aims This study reviews the use of a titanium mesh cage (TMC) as an adjunct to intramedullary nail or plate reconstruction of an extra-articular segmental long bone defect. Patients and Methods A total of 17 patients (aged 17 to 61 years) treated for a segmental long bone defect by nail or plate fixation and an adjunctive TMC were included. The bone defects treated were in the tibia (nine), femur (six), radius (one), and humerus (one). The mean length of the segmental bone defect was 8.4 cm (2.2 to 13); the mean length of the titanium mesh cage was 8...
May 1, 2018: Bone & Joint Journal
https://www.readbyqxmd.com/read/29701091/a-comparison-of-the-cost-effectiveness-of-intramedullary-nail-fixation-and-locking-plate-fixation-in-the-treatment-of-adult-patients-with-an-extra-articular-fracture-of-the-distal-tibia
#20
M Maredza, S Petrou, M Dritsaki, J Achten, J Griffin, S E Lamb, N R Parsons, M L Costa
Aim The aim of this study was to compare the cost-effectiveness of intramedullary nail fixation and 'locking' plate fixation in the treatment of extra-articular fractures of the distal tibia. Patients and Methods An economic evaluation was conducted from the perspective of the United Kingdom National Health Service (NHS) and personal social services (PSS), based on evidence from the Fixation of Distal Tibia Fractures (UK FixDT) multicentre parallel trial. Data from 321 patients were available for analysis. Costs were collected prospectively over the 12-month follow-up period using trial case report forms and participant-completed questionnaires...
May 1, 2018: Bone & Joint Journal
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