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https://www.readbyqxmd.com/read/29330991/diaphyseal-nutrient-foramina-in-dried-human-adult-long-bones-of-lower-limb-in-pakistan
#1
Ejaz Afzal, Fatima Sherin, Omair Khan, Noaman Hussain Siddiqui
BACKGROUND: osteogenesis needs circulation of blood in the bones. Bone growth, repair of fracture, maintenance of bone vitality and other injures also need blood circulation in proper way. Blood is allowed to flow via holes in the diaphysis, which are called as nutrient foramina. METHODS: The crosssectional study was done in the department of Anatomy, Ayub and Khyber Medical College (Osteology Sections). The aim was to observe diaphyseal nutrient foramina in the human long bones of the lower limb...
October 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/29317214/case-series-use-of-glyceryl-trinitrate-patches-to-improve-peripheral-circulation-in-children-with-severe-neurodisability
#2
Frances Morrison, Jack Fairhurst, Charlie Fairhurst
AIM: Evaluation of topical Glyceryl trinitrate as a therapeutic option to improve peripheral circulation in 16 children with severe complex neurodisability, poor capillary return and signs of vascular insufficiency, including discomfort. METHODS: If insufficient improvement in capillary return was obtained using conservative measures, a 5 mg GTN patch was placed each day on the front of the tibia of each leg. Children were reviewed clinically for up to 12 months of treatment...
December 31, 2017: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/29314242/co-morbidities-only-account-for-a-small-proportion-of-excess-mortality-after-fracture-a-record-linkage-study-of-individual-fracture-types
#3
Weiwen Chen, Judy M Simpson, Lyn M March, Fiona M Blyth, Dana Bliuc, Thach Tran, Tuan V Nguyen, John A Eisman, Jacqueline R Center
BACKGROUND: Non-hip non-vertebral fractures (NHNV) constitute the majority of osteoporotic fractures but few studies have examined the association between these fractures, co-morbidity and mortality. OBJECTIVE: To examine the relationship between individual non-hip non-vertebral fractures, co-morbidities and mortality. METHODS: Prospective population-based cohort of 267,043 subjects (45 and Up Study, Australia) had baseline questionnaires linked to hospital administrative and all-cause mortality data from 2006 - 2013...
January 4, 2018: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/29311146/impact-of-broad-regulatory-regions-on-gdf5-expression-and-function-in-knee-development-and-susceptibility-to-osteoarthritis
#4
Steve K Pregizer, Ata M Kiapour, Mariel Young, Hao Chen, Michael Schoor, Zun Liu, Jiaxue Cao, Vicki Rosen, Terence D Capellini
OBJECTIVES: Given the role of growth and differentiation factor 5 (GDF5) in knee development and osteoarthritis risk, we sought to characterise knee defects resulting from Gdf5 loss of function and how its regulatory regions control knee formation and morphology. METHODS: The brachypodism (bp) mouse line, which harbours an inactivating mutation in Gdf5, was used to survey how Gdf5 loss of function impacts knee morphology, while two transgenic Gdf5 reporter bacterial artificial chromosome mouse lines were used to assess the spatiotemporal activity and function of Gdf5 regulatory sequences in the context of clinically relevant knee anatomical features...
January 8, 2018: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29310377/fat-grafting-for-resurfacing-an-exposed-implant-in-lower-extremity-a-case-report
#5
Yun-Nan Lin, Chieh-Han Chuang, Shih-Hao Huang, Shu-Hung Huang, Tsai-Ming Lin, I-Wen Lin, Sin-Daw Lin, Yur-Ren Kuo
RATIONALE: Although numerous reconstruction protocols have been reported for lower leg trauma, those for distal leg trauma remain few. We present the case of a woman with an implant exposure wound, who was successfully treated through fat grafting, without major flap surgery. PATIENT CONCERNS: An 83-year-old woman with an exposed implant in lower extremity received reconstruction surgery once and the surgery failed. She refused additional major surgery and negative pressure wound therapy...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29305233/anterolateral-distal-tibia-locking-plate-osteosynthesis-and-their-ability-to-capture-otac3-pilon-fragments
#6
Arun Aneja, T David Luo, Boshen Liu, Molina Domingo, Kerry Danelson, Jason J Halvorson, Eben A Carroll
BACKGROUND: Intra-articular Pilon fractures remain therapeutically challenging due to osteochondral fracturing and comminution, marginal impaction, and insult to the soft tissue envelope. The purpose of this study was to compare the efficacy of anterolateral distal tibial locking plates in capturing main fracture fragments in tibial plafond fractures. METHODS: From May 2011 to Dec 2015, 169 OTA C-type pilon fractures met inclusion and exclusion criteria with computed tomographic (CT) scans performed prior to definitive fixation...
December 16, 2017: Injury
https://www.readbyqxmd.com/read/29297724/effect-of-a-novel-mobilization-with-movement-procedure-on-anterolateral-ankle-impingement-a-case-report
#7
Sudarshan Anandkumar
This case report describes a 50-year-old male who presented with right anterolateral ankle pain managed unsuccessfully with rest, medications, bracing, injection, physical therapy, and massage therapy. Clinical diagnosis of anterolateral ankle impingement was based on concordant symptom reproduction with palpatory tenderness and a positive lateral synovial impingement test. This case report is a potential first time description of the successful management of anterolateral ankle impingement utilizing a novel Mulligan's mobilization with movement procedure (consisting of internal rotation of the distal tibia) and taping with immediate improvements noted in pain, range of motion, and function...
January 3, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29286974/a-combined-distal-tibial-turn-up-plasty-and-intercalary-calcaneal-osteocutaneous-fillet-flap-for-salvage-of-a-transtibial-amputation-a-case-report
#8
Sean M Wade, Colin Harrington, Mark Fleming, Benjamin K Potter
CASE: This case demonstrates the successful attempt at a combined distal tibial turn-up plasty and intercalary calcaneal osteocutaneous fillet flap to increase functional limb length in order to salvage a transtibial amputation following a high-energy blast injury. CONCLUSION: A transtibial amputation is preferred over more proximal levels of amputation because of the decreased energy expenditure that is required for ambulation. In cases where there is not enough viable tibia to allow for a transtibial level of amputation, combining a calcaneal osteocutaneous fillet flap with a distal tibial turn-up plasty can be utilized to optimize residual limb length for a transtibial amputation...
October 2017: JBJS Case Connector
https://www.readbyqxmd.com/read/29278746/accuracy-of-mri-based-finite-element-assessment-of-distal-tibia-compared-to-mechanical-testing
#9
Chamith S Rajapakse, Elizabeth A Kobe, Alexandra S Batzdorf, Michael W Hast, Felix W Wehrli
High-resolution MRI-derived finite element analysis (FEA) has been used in translational research to estimate the mechanical competence of human bone. However, this method has yet to be validated adequately under in vivo imaging spatial resolution or signal-to-noise conditions. We therefore compared MRI-based metrics of bone strength to those obtained from direct, mechanical testing. The study was conducted on tibiae from 17 human donors (12 males and five females, aged 33 to 88years) with no medical history of conditions affecting bone mineral homeostasis...
December 23, 2017: Bone
https://www.readbyqxmd.com/read/29277058/the-ifst-an-instrumented-version-of-the-fukuda-stepping-test-for-balance-assessment
#10
Valeria Belluscio, Elena Bergamini, Marco Iosa, Marco Tramontano, Giovanni Morone, Giuseppe Vannozzi
The maintenance of the upright posture during dynamic balance requires the integration of sensory inputs regulated by the brain. After a neurological event, the assessment of balance control impairments is crucial for supporting health professionals in the design of personalized rehabilitation protocols. A commonly used test to assess balance ability is the Fukuda Stepping Test (FST). However, the clinical parameters traditionally considered are not fully representative of the patient's motor ability. The purpose of this study was to devise an instrumented version of the FST (iFST) that embodies inertial sensors and allows to obtain individual motor strategy information...
December 16, 2017: Gait & Posture
https://www.readbyqxmd.com/read/29276733/decisive-differences-in-the-bone-repair-processes-of-the-metaphysis-and-diaphysis-in-young-mice
#11
Satoshi Inoue, Hirotada Otsuka, Jiro Takito, Masanori Nakamura
Fractures are common traumatic injuries that mainly occur in the metaphyses of long bones such as the proximal humerus, distal radius, and proximal femur. However, most studies of fracture repair processes have focused on the diaphyseal region. In this study, we compared the bone repair processes of the metaphysis and the diaphysis of the mouse tibia. Bone apertures were formed in the tibial metaphysis and diaphysis. At indicated times after surgery, samples were collected, and the healing process was investigated using micro-computed tomography, as well as histological, immunohistochemical, and mRNA expression analyses...
June 2018: Bone Reports
https://www.readbyqxmd.com/read/29273293/distinct-features-of-trampoline-related-orthopedic-injuries-in-children-aged-under-6-years
#12
Eun Seok Choi, Jin Heon Hong, Jae Ang Sim
INTRODUCTION: Concern has been growing about trampoline-related injuries among young children. Several published policy statements have repeatedly recommended that children younger than 6 years should not use trampolines. However, few studies have investigated the injuries caused by trampoline-related accidents among young children. This study aimed to identify the distinct features of trampoline-related orthopedic injuries in children younger than 6 years. METHODS: We retrospectively reviewed the medical records of pediatric patients aged between 0 and 16 years who visited our regional emergency center due to trampoline-related orthopedic injuries between 2012 and 2015...
December 16, 2017: Injury
https://www.readbyqxmd.com/read/29258687/analysis-of-mortality-and-fixation-failure-in-geriatric-fractures-using-quantitative-computed-tomography
#13
Tyler S Pidgeon, Joey P Johnson, Matthew E Deren, Andrew R Evans, Roman A Hayda
OBJECTIVES: While osteoporosis has been shown to be a contributing factor in low energy fractures in the elderly, limited data exists regarding the correlation of bone mineral density (BMD) and T-Scores to mortality and failure of fracture fixation. This study seeks to determine the relationship between femoral neck BMD in elderly patients with typical geriatric fractures and mortality and fracture fixation failure using Quantitative Computed Tomography (QCT). MATERIALS AND METHODS: Patients over the age of 65 who sustained fractures of the proximal humerus, distal radius, pelvic ring, acetabulum, hip, proximal tibia, and ankle who also underwent a CT scan that included an uninjured femoral neck were retrospectively reviewed...
December 15, 2017: Injury
https://www.readbyqxmd.com/read/29239274/magnetic-resonance-feature-of-paintbrush-borders-sign-as-a-novel-way-to-predict-recurrence-of-giant-cell-tumor-of-bone-after-curettage-a-pilot-study
#14
Yifeng He, Jun Wang, Ji Zhang, Lianjun Du, Yong Lu, Jianqiang Xu, Fei Yuan, Yimin Tan, Xiaoyi Ding
Objective To identify the prognostic factors for local recurrence of giant cell tumor of bone (GCTB) through assessment of the preoperative imaging features of the tumor border. Methods Patients with GCTBs treated with intralesional procedures in the proximal tibia and distal femur were prospectively enrolled and then followed up for at least 2 years. The GCTBs were grouped according to their preoperative imaging features. GCTBs treated with en bloc resection were enrolled for investigation of the pathologic basis of specific imaging features...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/29237543/diagnosis-and-management-of-mcfarland-fractures-a-case-report-and-review-of-the-literature
#15
M Birt, B Vopat, P Schroeppel, A Tarakemeh, B Everist, S Mullen
BACKGROUND: McFarland fracture is the eponym for a rare Salter Harris III or IV fracture involving the medial distal tibia. These fractures can be difficult to diagnose without a high index suspicion and appropriate radiographic imaging. These fractures may result in significant growth disturbances to the pediatric patient. When diagnosed and treated acutely, these fractures can be managed with cast immobilization and close follow up. If diagnoses in a delayed fashion they can result in significant morbidity including prolonged casting and possible surgical treatment...
December 9, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29236176/na18f-accumulates-on-the-compressive-side-of-peri-implant-bone-under-immediate-loading
#16
Miou Yamamoto, Toru Ogawa, Masayoshi Yokoyama, Yoshihito Funaki, Kenta Shobara, Aya Shibamoto, Juan Ramón Vanegas Sáenz, Keiichi Sasaki
This study aimed to examine the dynamic change in bone metabolism by immediate loading in several sites around implants using high-resolution Na18F-PET scan. Two titanium implants (Ø 1.2 mm) were inserted parallel to each other in the right tibiae of Wistar rats (n = 4). The left tibia was set as control side. One day after insertion, closed coil springs of 4.0 N were attached to the expose superior portions of the implants to apply a continuous mechanical stress. The rats with fluorine-18 (18F) ion (5 mCi/rat) intravenously injected were scanned by PET scanner at 4, 7, 14, 28 days after load application...
December 13, 2017: Odontology
https://www.readbyqxmd.com/read/29222689/long-term-quantitative-evaluation-of-muscle-and-bone-wasting-induced-by-botulinum-toxin-in-mice-using-microcomputed-tomography
#17
Hélène Libouban, Claude Guintard, Nicolas Minier, Eric Aguado, Daniel Chappard
Muscle and bone masses are highly correlated and muscles impose large loads on bone. Muscle wasting that accompanies bone loss has been poorly investigated. 21 female mice were spread into seven groups. At day 0, 18 mice received Botulinum toxin (BTX) injection in the quadriceps muscle to induce paralysis of the right hind limb; the left contralateral side was used as control. Mice were sacrificed at 7, 14, 21, 28, 56 and 90 days post-injection. A remaining group was sacrificed at day 0. Trabecular bone volume was determined by microcomputed tomography (microCT) at the distal femur and tibia proximal metaphyses on both sides...
December 8, 2017: Calcified Tissue International
https://www.readbyqxmd.com/read/29212694/minimising-aseptic-loosening-in-extreme-bone-resections-custom-made-tumour-endoprostheses-with-short-medullary-stems-and-extra-cortical-plates
#18
J D Stevenson, C Wigley, H Burton, S Ghezelayagh, G Morris, S Evans, M Parry, L Jeys
AIMS: Following the resection of an extensive amount of bone in the treatment of a tumour, the residual segment may be insufficient to accept a standard length intramedullary cemented stem. Short-stemmed endoprostheses conceivably have an increased risk of aseptic loosening. Extra-cortical plates have been added to minimise this risk by supplementing fixation. The aim of this study was to investigate the survivorship of short-stemmed endoprostheses and extra-cortical plates. PATIENTS AND METHODS: The study involved 37 patients who underwent limb salvage surgery for a primary neoplasm of bone between 1998 and 2013...
December 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/29212516/a-finite-element-model-of-the-lower-limb-during-stance-phase-of-gait-cycle-including-the-muscle-forces
#19
Arnaud Diffo Kaze, Stefan Maas, Pierre-Jean Arnoux, Claude Wolf, Dietrich Pape
BACKGROUND: Results of finite element (FE) analyses can give insight into musculoskeletal diseases if physiological boundary conditions, which include the muscle forces during specific activities of daily life, are considered in the FE modelling. So far, many simplifications of the boundary conditions are currently made. This study presents an approach for FE modelling of the lower limb for which muscle forces were included. METHODS: The stance phase of normal gait was simulated...
December 7, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29198577/bone-autografts-allografts-placed-simultaneously-with-dental-implants-in-rabbits
#20
Marna Ribeiro, Erica Hohlenwerger Fraguas, Keila Ilse Cangussu Brito, Yeon Jung Kim, Debora Pallos, Wilson Roberto Sendyk
OBJECTIVE: This study compared stability, removal torque, bone implant contact (BIC) and area (BA) of implants installed simultaneously with onlay autografts or allografts in rabbits' tibias. MATERIAL AND METHODS: Total of 18 rabbits were used in this study. Fresh frozen allografts were obtained from six animals at T(-6). Two implants with autogenous grafts (Group 1) or allografts (Group 2) were simultaneously inserted into both sides of the tibiae in a vertical periimplant defect model at T0...
November 11, 2017: Journal of Cranio-maxillo-facial Surgery
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