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https://www.readbyqxmd.com/read/29340677/association-of-bariatric-surgery-using-laparoscopic-banding-roux-en-y-gastric-bypass-or-laparoscopic-sleeve-gastrectomy-vs-usual-care-obesity-management-with-all-cause-mortality
#1
Orna Reges, Philip Greenland, Dror Dicker, Morton Leibowitz, Moshe Hoshen, Ilan Gofer, Laura J Rasmussen-Torvik, Ran D Balicer
Importance: Bariatric surgery is an effective and safe approach for weight loss and short-term improvement in metabolic disorders such as diabetes. However, studies have been limited in most settings by lack of a nonsurgical group, losses to follow-up, missing data, and small sample sizes in clinical trials and observational studies. Objective: To assess the association of 3 common types of bariatric surgery compared with nonsurgical treatment with mortality and other clinical outcomes among obese patients...
January 16, 2018: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29336941/age-specific-excess-mortality-patterns-and-transmissibility-during-the-1889-1890-influenza-pandemic-in-madrid-spain
#2
Diego Ramiro, Sara Garcia, Yolanda Casado, Laura Cilek, Gerardo Chowell
PURPOSE: Although the 1889-1890 influenza pandemic was one of the most important epidemic events of the 19th century, little is known about the mortality impact of this pandemic based on detailed respiratory mortality data sets. METHODS: We estimated excess mortality rates for the 1889-1890 pandemic in Madrid from high-resolution respiratory and all-cause individual-level mortality data retrieved from the Gazeta de Madrid, the Official Bulletin of the Spanish government...
December 27, 2017: Annals of Epidemiology
https://www.readbyqxmd.com/read/29336032/my-mind-your-mind-and-god-s-mind-how-children-and-adults-conceive-of-different-agents-moral-beliefs
#3
Larisa Heiphetz, Jonathan D Lane, Adam Waytz, Liane L Young
Extending prior research on belief attributions, we investigated the extent to which 5- to 8-year-olds and adults distinguish their beliefs and other humans' beliefs from God's beliefs. In Study 1, children reported that all agents held the same beliefs, whereas adults drew greater distinctions among agents. For example, adults reported that God was less likely than humans to view behaviors as morally acceptable. Study 2 additionally investigated attributions of beliefs about controversial behaviours (e.g., telling prosocial lies) and belief stability...
January 16, 2018: British Journal of Developmental Psychology
https://www.readbyqxmd.com/read/29334904/association-of-kidney-disease-quality-of-life-kdqol-36-with-mortality-and-hospitalization-in-older-adults-receiving-hemodialysis
#4
Rasheeda K Hall, Alison Luciano, Carl Pieper, Cathleen S Colón-Emeric
BACKGROUND: For older adults receiving dialysis, health-related quality of life is not often considered in prognostication of death or future hospitalizations. To determine if routine health-related quality of life measures may be useful for prognostication, the objective of this study is to determine the extent of association of Kidney Disease Quality of Life (KDQOL-36) subscales with adverse outcomes in older adults receiving dialysis. METHODS: This is a longitudinal study of 3500 adults aged ≥75 years receiving dialysis in the United States in 2012 and 2013...
January 15, 2018: BMC Nephrology
https://www.readbyqxmd.com/read/29330753/transfer-of-critically-ill-adults-assessing-the-need-for-training
#5
Ruth-Aoibheann O'Leary, Brian Marsh, Paul O'Connor
BACKGROUND: Transfer of critically ill patients within the hospital is commonly associated with adverse incidents, but, despite this, no standardised training exists on how to carry out this task. Very little information is published in the literature on the learning needs of staff undertaking these transfers, and this limits our ability to provide a focused and appropriate educational intervention. AIMS: This study aimed to explore the organisational, environmental and individual issues that increase risk to patients during intrahospital transport (IHT) and to explore the potential educational solutions to these issues as articulated by these practitioners...
January 12, 2018: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/29330636/a-randomised-trial-comparing-the-pharmacokinetics-and-safety-of-the-biosimilar-ct-p6-with-reference-trastuzumab
#6
Francisco J Esteva, Justin Stebbing, Rebecca N Wood-Horrall, Peter J Winkle, Sung Young Lee, Sang Joon Lee
PURPOSE: Access to trastuzumab, a valuable anti-cancer treatment, can be limited by cost. The primary aim of this study was to evaluate and compare the PK profiles of CT-P6, a biosimilar of trastuzumab, and US-licensed reference trastuzumab (Herceptin®) in healthy subjects. Secondary study aims included comparison of the safety and immunogenicity of CT-P6 and reference trastuzumab in these subjects. METHODS: We performed a single-dose, randomised, double-blind, parallel group study (NCT02665637) comparing CT-P6 with reference trastuzumab (6 mg/kg, 90 min intravenous infusion) in 70 healthy adult males...
January 12, 2018: Cancer Chemotherapy and Pharmacology
https://www.readbyqxmd.com/read/29329363/validity-of-teleneuropsychological-assessment-in-older-patients-with-cognitive-disorders
#7
Hannah E Wadsworth, Kaltra Dhima, Kyle B Womack, John Hart, Myron F Weiner, Linda S Hynan, C Munro Cullum
Objective: The feasibility and reliability of neuropsychological assessment at a distance have been demonstrated, but the validity of this testing medium has not been adequately demonstrated. The purpose of this study was to determine the ability of video teleconferencing administration of neuropsychological measures (teleneuropsychology) in discriminating cognitively impaired from non-impaired groups of older adults. It was predicted that measures administered via video teleconference would distinguish groups and that the magnitude of differences between impaired and non-impaired groups would be similar to group differences achieved in traditional administration...
January 10, 2018: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/29327090/alcohol-use-and-unprotected-sex-among-hiv-infected-ugandan-adults-findings-from-an-event-level-study
#8
Sarah E Woolf-King, Robin Fatch, Debbie M Cheng, Winnie Muyindike, Christine Ngabirano, Allen Kekibiina, Nneka Emenyonu, Judith A Hahn
While alcohol is a known risk factor for HIV infection in sub-Saharan Africa (SSA), studies designed to investigate the temporal relationship between alcohol use and unprotected sex are lacking. The purpose of this study was to determine whether alcohol used at the time of a sexual event is associated with unprotected sex at that same event. Data for this study were collected as part of two longitudinal studies of HIV-infected Ugandan adults. A structured questionnaire was administered at regularly scheduled cohort study visits in order to assess the circumstances (e...
January 11, 2018: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/29322491/influence-of-prehospital-function-and-strength-on-outcomes-of-critically-ill-older-adults
#9
D Clark Files, Rebecca Neiberg, Julia Rushing, Peter E Morris, Michael P Young, Hilsa Ayonayon, Tamara Harris, Anne Newman, Susan Rubin, Eric Shiroma, Denise Houston, Michael E Miller, Stephen B Kritchevsky
OBJECTIVES: To understand the influence of prehospital physical function and strength on clinical outcomes of critically ill older adults. DESIGN: Secondary analysis of prospective cohort study. SETTING: Health, Aging and Body Composition (Health ABC) Study. PARTICIPANTS: Of 3,075 older adult Health ABC participants, we identified 575 (60% white, 61% male, mean age 79) with prehospital function or grip strength measurements within 2 years of an intensive care unit stay...
January 11, 2018: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29321705/attention-deficit-hyperactivity-disorder-and-nicotine-dependence-in-adults
#10
Bülent Bilgi, Umut Mert Aksoy, Özge Şahmelikoğlu Onur, Ayşe Fulya Maner
Introduction: The aim of this study is to assess clinical characteristics and smoking profiles of individuals diagnosed with attention-deficit/hyperactivity disorder (ADHD) and compare their nicotine dependence status with healthy controls for better understanding the mutual and complex relationship between ADHD and smoking. Methods: We included the following participants in the study: 40 adults with the diagnosis of ADHD, 40 participants who visited the smoking cessation polyclinic without any psychiatric disorders, and 40 healthy controls...
December 2017: Noro Psikiyatri Arsivi
https://www.readbyqxmd.com/read/29318644/description-and-prognostic-significance-of-the-kinetics-of-minimal-residual-disease-status-in-adults-with-acute-lymphoblastic-leukemia-treated-with-hypercvad
#11
Ryan D Cassaday, Philip A Stevenson, Brent L Wood, Pamela S Becker, Paul C Hendrie, Brenda M Sandmaier, Jerald L Radich, Andrei R Shustov
HyperCVAD is a commonly-used regimen for adults with newly-diagnosed acute lymphoblastic leukemia (ALL). However, relatively little is known about the application of minimal residual disease (MRD) detection with this treatment. To address this, we studied 142 adults with ALL treated with hyperCVAD over a 10-year period who had MRD assessed by either multi-parameter flow cytometry or (for patients with Philadelphia chromosome positive ALL) reverse transcriptase polymerase chain reaction for the BCR-ABL1 translocation...
January 10, 2018: American Journal of Hematology
https://www.readbyqxmd.com/read/29317533/the-social-genome-of-friends-and-schoolmates-in-the-national-longitudinal-study-of-adolescent-to-adult-health
#12
Benjamin W Domingue, Daniel W Belsky, Jason M Fletcher, Dalton Conley, Jason D Boardman, Kathleen Mullan Harris
Humans tend to form social relationships with others who resemble them. Whether this sorting of like with like arises from historical patterns of migration, meso-level social structures in modern society, or individual-level selection of similar peers remains unsettled. Recent research has evaluated the possibility that unobserved genotypes may play an important role in the creation of homophilous relationships. We extend this work by using data from 5,500 adolescents from the National Longitudinal Study of Adolescent to Adult Health (Add Health) to examine genetic similarities among pairs of friends...
January 9, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29317146/momentary-factors-during-marijuana-use-as-predictors-of-lapse-during-attempted-abstinence-in-young-adults
#13
Lydia A Shrier, Vishnudas Sarda, Cassandra Jonestrask, Sion Kim Harris
INTRODUCTION: Young adults using marijuana heavily often try multiple times to quit on their own. We sought to identify momentary experiences during marijuana use that could aid in predicting lapse when young adults subsequently attempt abstinence. METHODS: Young adults (N=34) age 18-25 using marijuana ≥5days/week and planning to quit completed a survey of sociodemographic characteristics, substance use, marijuana expectancies, use motives, perceived social support, and confidence to abstain...
December 29, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/29315678/modifiable-correlates-of-illness-perceptions-in-adults-with-chronic-somatic-conditions-a-systematic-review
#14
Seher Arat, Diederik De Cock, Philip Moons, Joris Vandenberghe, René Westhovens
When individuals become ill, they want to understand and give meaning to their illness. The interpretation of this illness experience, or illness perception, is influenced by a range of individual, contextual, and cultural factors. Some of these factors may be modifiable by nursing interventions. The purpose of this systematic review was to investigate which modifiable factors were correlated with illness perceptions across studies of adults with different chronic somatic diseases. Using search terms tailored to each of four electronic databases, studies retrieved were reviewed by two independent evaluators, and each relevant article was assessed for methodological quality...
January 9, 2018: Research in Nursing & Health
https://www.readbyqxmd.com/read/29310541/family-members-existential-and-moral-dilemmas-with-coercion-in-mental-healthcare
#15
Reidun Norvoll, Marit Helene Hem, Hilde Lindemann
Coercion in mental healthcare does not only affect the patient, but also the patient's families. Using data from interviews with 36 family members of adult and adolescent people with mental health problems and coercion experiences, the present narrative study explores family members' existential and moral dilemmas regarding coercion and the factors influencing these dilemmas. Four major themes are identified: the ambiguity of coercion; struggling to stay connected and establishing collaboration; worries and distress regarding compulsory care; and dilemmas regarding initiating coercion...
January 1, 2018: Qualitative Health Research
https://www.readbyqxmd.com/read/29304799/study-protocol-evaluation-of-specialized-outpatient-palliative-care-sopc-in-the-german-state-of-hesse-elsah-study-work-package-ii-palliative-care-for-pediatric-patients
#16
Lisa-R Ulrich, Dania Gruber, Michaela Hach, Stefan Boesner, Joerg Haasenritter, Katrin Kuss, Hannah Seipp, Ferdinand M Gerlach, Antje Erler
BACKGROUND: In 2007, the European Association of Palliative Care (EAPC) provided a comprehensive set of recommendations and standards for the provision of adequate pediatric palliative care. A number of studies have shown deficits in pediatric palliative care compared to EAPC standards. In Germany, pediatric palliative care patients can be referred to specialized outpatient palliative care (SOPC) services, which are known to enhance quality of life, e.g. by avoiding hospitalization. However, current regulations for the provision of SOPC in Germany do not account for the different circumstances and needs of children and their families compared to adult palliative care patients...
January 5, 2018: BMC Palliative Care
https://www.readbyqxmd.com/read/29303866/pet-and-ictal-spect-can-be-helpful-for-localizing-epileptic-foci
#17
Tim J von Oertzen
PURPOSE OF REVIEW: Functional neuroimaging with PET and SPECT is a commonly used tool in presurgical evaluation. The following article reviews the literature of PET and SPECT in presurgical assessment of epilepsies published in the last year. RECENT FINDINGS: FDG-PET adds concomitant information in temporal and extratemporal lobe epilepsy in adults and children. The pattern of hypometabolism in FDG-PET is a good additional predictor or seizure outcome in TLE with mesial temporal sclerosis or negative MRI...
January 4, 2018: Current Opinion in Neurology
https://www.readbyqxmd.com/read/29302644/vestibular-function-in-a-group-of-adults-with-hiv-aids-on-haart
#18
Katijah Khoza-Shangase
Background: The high prevalence of HIV/AIDS and the established otological manifestations of the disease have important implications for research into vestibular function in this population. Materials and Methods: The main aim of the current study was to investigate and monitor the vestibular status in a group of adult patients with AIDS receiving Highly Active Antiretroviral Therapy (HAART) and other therapies in a hospital outpatient clinic in Gauteng, South Africa...
2018: African Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29298716/persistently-high-psychological-well-being-predicts-better-hdl-cholesterol-and-triglyceride-levels-findings-from-the-midlife-in-the-u-s-midus-longitudinal-study
#19
Barry T Radler, Attilio Rigotti, Carol D Ryff
BACKGROUND: Psychological correlates of blood lipid levels have been previously evaluated mostly in cross sectional studies. However, prospectively measured psychological factors might also predict favorable blood lipid profiles, thereby indicating a healthy mind/body interplay that is associated with less disease, better health and longer lives. METHODS: This paper examined whether longitudinal profiles of psychological well-being over 9-10 years are predictors of blood lipid profiles...
January 3, 2018: Lipids in Health and Disease
https://www.readbyqxmd.com/read/29298698/genotype-and-biotype-of-invasive-anopheles-stephensi-in-mannar-island-of-sri-lanka
#20
Sinnathamby N Surendran, Kokila Sivabalakrishnan, Kanapathy Gajapathy, Sivasingham Arthiyan, Tibutius T P Jayadas, Kalingarajah Karvannan, Selvarajah Raveendran, S H P Parakrama Karunaratne, Ranjan Ramasamy
BACKGROUND: Anopheles stephensi, the major vector of urban malaria in India, was recently detected for the first time in Sri Lanka in Mannar Island on the northwestern coast. Since there are different biotypes of An. stephensi with different vector capacities in India, a study was undertaken to further characterise the genotype and biotype of An. stephensi in Mannar Island. METHODS: Mosquito larvae were collected in Pesalai village in Mannar and maintained in the insectary until adulthood...
January 3, 2018: Parasites & Vectors
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