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https://www.readbyqxmd.com/read/29148324/the-impacts-of-medicaid-expansion-on-rural-low-income-adults-lessons-from-the-oregon-health-insurance-experiment
#1
Heidi Allen, Bill Wright, Lauren Broffman
Medicaid expansions through the Affordable Care Act began in January 2014, but we have little information about what is happening in rural areas where provider access and patient resources might be more limited. In 2008, Oregon held a lottery for restricted access to its Medicaid program for uninsured low-income adults not otherwise eligible for public coverage. The Oregon Health Insurance Experiment used this opportunity to conduct the first randomized controlled study of a public insurance expansion. This analysis builds off of previous work by comparing rural and urban survey outcomes and adds qualitative interviews with 86 rural study participants for context...
January 1, 2017: Medical Care Research and Review: MCRR
https://www.readbyqxmd.com/read/29145392/conservation-of-a-microrna-cluster-in-parasitic-nematodes-and-profiling-of-mirnas-in-excretory-secretory-products-and-microvesicles-of-haemonchus-contortus
#2
Henry Y Gu, Neil D Marks, Alan D Winter, William Weir, Thomas Tzelos, Tom N McNeilly, Collette Britton, Eileen Devaney
microRNAs are small non-coding RNAs that are important regulators of gene expression in a range of animals, including nematodes. We have analysed a cluster of four miRNAs from the pathogenic nematode species Haemonchus contortus that are closely linked in the genome. We find that the cluster is conserved only in clade V parasitic nematodes and in some ascarids, but not in other clade III species nor in clade V free-living nematodes. Members of the cluster are present in parasite excretory-secretory products and can be detected in the abomasum and draining lymph nodes of infected sheep, indicating their release in vitro and in vivo...
November 16, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29141837/user-acceptance-of-wrist-worn-activity-trackers-among-community-dwelling-older-adults-mixed-method-study
#3
Arjun Puri, Ben Kim, Olivier Nguyen, Paul Stolee, James Tung, Joon Lee
BACKGROUND: Wearable activity trackers are newly emerging technologies with the anticipation for successfully supporting aging-in-place. Consumer-grade wearable activity trackers are increasingly ubiquitous in the market, but the attitudes toward, as well as acceptance and voluntary use of, these trackers in older population are poorly understood. OBJECTIVE: The aim of this study was to assess acceptance and usage of wearable activity trackers in Canadian community-dwelling older adults, using the potentially influential factors as identified in literature and technology acceptance model...
November 15, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29141463/once-monthly-injection-of-paliperidone-palmitate-in-patients-with-recently-diagnosed-and-chronic-schizophrenia-a-post-hoc-comparison-of-efficacy-and-safety
#4
Tianmei Si, Jianmin Zhuo, Ibrahim Turkoz, Maju Mathews, Wilson Tan, Yu Feng
BACKGROUND: The use of long-acting injectable antipsychotics in recently diagnosed schizophrenia remains less explored. We evaluated the efficacy and safety of paliperidone palmitate once-monthly (PP1M) treatment in adult patients with recently diagnosed vs. chronic schizophrenia. RESEARCH DESIGN AND METHODS: These post-hoc analyses included two multicenter studies. Study 1 (NCT01527305) enrolled recently diagnosed (≤5 years) and chronic (>5 years) patients; Study 2 (NCT01051531) enrolled recently diagnosed patients only...
November 15, 2017: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/29140899/isotemporal-substitution-of-sedentary-behavior-and-physical-activity-on-function
#5
Nicholas L Lerma, Chi C Cho, Ann M Swartz, Nora E Miller, Kevin G Keenan, Scott J Strath
The amount of time spent in sedentary behaviors (SB) progressively increases with age, while reducing time spent in light (LPA) and moderate-to-vigorous physical activity (MVPA). These trajectories in PA and SB are linked to accelerated reductions in physical functioning. PURPOSE: To examine the association of substituting SB time with LPA and MVPA on physical function in older adults. METHODS: Ninety-one older adults (mean age: 70.7 ± 10.2 yr) wore a hip-mounted accelerometer to measure SB, LPA, and MVPA time...
November 14, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29139332/the-views-of-adults-with-huntington-s-disease-on-assisted-dying-a-qualitative-exploration
#6
Laurence Regan, Nancy J Preston, Fiona J R Eccles, Jane Simpson
BACKGROUND: Assisted dying is frequently debated publicly and research often includes the views of health professionals on this issue. However, the views of people with life-limiting conditions, for whom this issue is likely to have a different resonance, are less well represented. AIM: The purpose of this study was to explore the views of people who live with the inevitability of developing Huntington's disease, a genetically transmitted disease which significantly limits life, on assisted dying...
November 1, 2017: Palliative Medicine
https://www.readbyqxmd.com/read/29138878/higher-cost-of-hospitalizations-for-non-cardiac-diagnoses-in-adults-with-congenital-heart-disease
#7
Michael D Seckeler, Ian D Thomas, Jennifer Andrews, Omar Meziab, Tabitha Moe, Elissa Heller, Scott E Klewer
Adults with congenital heart disease (CHD) are a rapidly increasing population and their impact on healthcare resources is not fully understood. The purpose of this study was to describe the costs of hospitalizations for non-cardiac disease for adults with CHD. We conducted a retrospective review of hospital discharge data from the University HealthSystem Consortium Clinical Data Base/Resource Manager from January 2011 through December 2013. Patients were ≥ 18 years old at admission with any ICD-9 code for moderate or high severity CHD; cardiac surgical admissions were excluded...
November 15, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/29128788/inclusion-of-service-robots-in-the-daily-lives-of-frail-older-users-a-step-by-step-definition-procedure-on-users-requirements
#8
Álvaro García-Soler, David Facal, Unai Díaz-Orueta, Lucia Pigini, Lorenzo Blasi, Renxi Qiu
The implications for the inclusion of robots in the daily lives of frail older adults, especially in relation to these population needs, have not been extensively studied. The "Multi-Role Shadow Robotic System for Independent Living" (SRS) project has developed a remotely-controlled, semi-autonomous robotic system to be used in domestic environments. The objective of this paper is to document the iterative procedure used to identify, select and prioritize user requirements. Seventy-four requirements were identified by means of focus groups, individual interviews and scenario-based interviews...
October 31, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/29128736/optimal-practice-conditions-enhance-the-benefits-of-gradually-increasing-error-opportunities-on-retention-of-a-stepping-sequence-task
#9
Danielle Levac, Kate Driscoll, Jessica Galvez, Kathleen Mercado, Lindsey O'Neil
INTRODUCTION: Physical therapists should implement practice conditions that promote motor skill learning after neurological injury. Errorful and errorless practice conditions are effective for different populations and tasks. Errorful learning provides opportunities for learners to make task-relevant choices. Enhancing learner autonomy through choice opportunities is a key component of the Optimizing Performance through Intrinsic Motivation and Attention for Learning (OPTIMAL) theory of motor learning...
November 9, 2017: Human Movement Science
https://www.readbyqxmd.com/read/29126930/white-matter-integrity-mediates-decline-in-age-related-inhibitory-control
#10
Peipei Li, Angeliki Tsapanou, Razlighi R Qolamreza, Yunglin Gazes
Previous DTI studies have reported associations between white matter integrity and performance on the Stroop interference task. The current study aimed to add to these studies of inhibitory control by investigating how the differences in age and in white matter integrity relate to Stroop performance, and to examine whether the effect of age on Stroop performance is mediated by white matter integrity. 179 healthy adults from 20 to 80 years old were recruited in the study. DTI data were processed through TRACULA and the mean fractional anisotropy (FA) of 18 major white matter tracts were extracted and used for statistical analysis...
November 7, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/29126126/exposure-to-point-of-sale-marketing-of-cigarettes-and-e-cigarettes-as-predictors-of-smoking-cessation-behaviors
#11
Dale S Mantey, Keryn E Pasch, Alexandra Loukas, Cheryl L Perry
Introduction: Cue-reactivity theory suggests smoking-related visual cues such as point-of-sale (POS) marketing (e.g., advertising, product displays) may undermine cessation attempts by causing an increase in nicotine cravings among users. This study examined the relationship between recall of exposure to POS marketing and subsequent cessation behaviors among young adult cigarette smokers. Methods: Participants included 813 18-29 year old (m=21.1, sd=2.70) current cigarette smokers attending 24 Texas colleges...
November 6, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/29126059/enhancing-early-psychosis-treatment-using-smartphone-technology-a-longitudinal-feasibility-and-validity-study
#12
Tara A Niendam, Laura M Tully, Ana-Maria Iosif, Divya Kumar, Kathleen E Nye, Jennifer C Denton, Lauren N Zakskorn, Taylor L Fedechko, Katherine M Pierce
Smartphone applications that promote symptom tracking and self-management may improve treatment of serious mental illness (SMI). Although feasibility has been established in chronic adult outpatient or inpatient SMI samples, no data exist regarding implementation of smartphone technology in adolescent and young adult populations as part of early psychosis (EP) outpatient care. We implemented a smartphone "app" plus clinician Dashboard as an add-on treatment tool in the University of California, Davis Early Psychosis Program...
October 21, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29125851/new-evidence-showing-that-the-destruction-of-gut-bacteria-by-antibiotic-treatment-could-increase-the-honey-bee-s-vulnerability-to-nosema-infection
#13
Jiang Hong Li, Jay D Evans, Wen Feng Li, Ya Zhou Zhao, Gloria DeGrandi-Hoffman, Shao Kang Huang, Zhi Guo Li, Michele Hamilton, Yan Ping Chen
It has become increasingly clear that gut bacteria play vital roles in the development, nutrition, immunity, and overall fitness of their eukaryotic hosts. We conducted the present study to investigate the effects of gut microbiota disruption on the honey bee's immune responses to infection by the microsporidian parasite Nosema ceranae. Newly emerged adult workers were collected and divided into four groups: Group I-no treatment; Group II-inoculated with N. ceranae, Group III-antibiotic treatment, and Group IV-antibiotic treatment after inoculation with N...
2017: PloS One
https://www.readbyqxmd.com/read/29122156/long-term-safety-and-efficacy-of-reslizumab-in-patients-with-eosinophilic-asthma
#14
Kevin Murphy, Joshua Jacobs, Leif Bjermer, John M Fahrenholz, Yael Shalit, Margaret Garin, James Zangrilli, Mario Castro
BACKGROUND: In placebo-controlled trials, reslizumab, an anti-IL-5 monoclonal antibody, significantly reduced asthma exacerbations and improved lung function and asthma control in patients with eosinophilic asthma. OBJECTIVE: This open-label extension study evaluated safety and efficacy of reslizumab for up to 24 months. METHODS: After participation in 1 of 3 placebo-controlled, phase III trials in moderate-to-severe eosinophilic asthma, patients received reslizumab 3...
November 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29121797/effectiveness-of-acupuncture-and-electroacupuncture-for-chronic-neck-pain-a-systematic-review-and-meta-analysis
#15
See Yoon Seo, Ki-Beom Lee, Joon-Shik Shin, Jinho Lee, Me-Riong Kim, In-Hyuk Ha, Youme Ko, Yoon Jae Lee
The aim of this systematic review was to assess evidence from randomized controlled trials (RCTs) on the effectiveness and safety of acupuncture and electroacupuncture in patients with chronic neck pain. We searched nine databases including Chinese, Japanese and Korean databases through 30 July 2016. The participants were adults with chronic neck pain and were treated with acupuncture or electroacupuncture. Eligible trials were those with intervention groups receiving acupuncture and electroacupuncture with or without active control, and control groups receiving other conventional treatments such as physical therapy or medication...
November 9, 2017: American Journal of Chinese Medicine
https://www.readbyqxmd.com/read/29119301/whole-body-vibration-added-to-treatment-as-usual-is-effective-in-adolescents-with-depression-a-partly-randomized-three-armed-clinical-trial-in-inpatients
#16
Heidrun Lioba Wunram, Stefanie Hamacher, Martin Hellmich, Maxi Volk, Franziska Jänicke, Franziska Reinhard, Wilhelm Bloch, Philipp Zimmer, Christine Graf, Eckhard Schönau, Gerd Lehmkuhl, Stephan Bender, Oliver Fricke
There is growing evidence for the effectiveness of exercise in the treatment of adult major depression. With regard to adolescents, clinical trials are scarce. Due to the inherent symptoms of depression (lack of energy, low motivation to exercise), endurance training forms could be too demanding especially in the first weeks of treatment. We hypothesized that an easy-to-perform passive muscular training on a whole body vibration (WBV) device has equal anti-depressive effects compared to a cardiovascular training, both administered as add-ons to treatment as usual (TAU)...
November 8, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/29115024/developmental-timing-differences-underlie-armor-loss-across-threespine-stickleback-populations
#17
Mark C Currey, Susan Bassham, Stephen Perry, William A Cresko
Comparing ontogenetic patterns within a well-described evolutionary context aids in inferring mechanisms of change, including heterochronies or deletion of developmental pathways. Because selection acts on phenotypes throughout ontogeny, any within-taxon developmental variation has implications for evolvability. We compare ontogenetic order and timing of locomotion and defensive traits in three populations of threespine stickleback that have evolutionarily divergent adult forms. This analysis adds to the growing understanding of developmental genetic mechanisms of adaptive change in this evolutionary model species by delineating when chondrogenesis and osteogenesis in two derived populations begin to deviate from the developmental pattern in their immediate ancestors...
November 2017: Evolution & Development
https://www.readbyqxmd.com/read/29112988/relationship-between-spending-on-electronic-cigarettes-30-day-use-and-disease-symptoms-among-current-adult-cigarette-smokers-in-the-u-s
#18
Tingting Yao, Wendy Max, Hai-Yen Sung, Stanton A Glantz, Rachel L Goldberg, Julie B Wang, Yingning Wang, James Lightwood, Janine Cataldo
OBJECTIVE: To examine the relationship between spending on electronic cigarettes (e-cigarettes) and disease symptoms compared with the relationship between 30-day e-cigarette use and disease symptoms among adult cigarette smokers in the U.S. METHODS: We analyzed data from the Tobacco and Attitudes Beliefs Survey which included 533 respondents aged 24+ who were current cigarette smokers and e-cigarette ever users. Fifteen self-reported disease symptoms were included as outcome variables...
2017: PloS One
https://www.readbyqxmd.com/read/29112181/vitamin-d-supplementation-in-respiratory-diseases-evidence-from-rct
#19
Carolien Mathyssen, Ghislaine Gayan-Ramirez, Roger Bouillon, Wim Janssens
Pulmonary diseases are one of the most important causes for morbidity and mortality. Although vitamin D is best known for its role in calcium, phosphorus and bone homeostasis, in the recent years vitamin D has gained attention because of a wide range of extra-skeletal effects including its immunomodulatory and antibacterial potential. Vitamin D deficiency is highly prevalent in chronic pulmonary diseases such as Chronic Obstructive Pulmonary Disease (COPD), cystic fibrosis, tuberculosis and asthma and several clinical studies have been conducted investigating the effect of vitamin D supplementation on disease outcomes...
November 2, 2017: Polish Archives of Internal Medicine
https://www.readbyqxmd.com/read/29111355/transstadial-transmission-of-larval-hemocoelic-infection-negatively-affects-development-and-adult-female-longevity-in-the-mosquito-anopheles-gambiae
#20
Lisa D Brown, Grayson A Thompson, Julián F Hillyer
During all life stages, mosquitoes are exposed to pathogens, and employ an immune system to resist or limit infection. Although much attention has been paid to how adult mosquitoes fight infection, little is known about how an infection during the larval stage affects the biology of the resultant adult. In this study, we investigated whether a bacterial infection in the hemocoel of the African malaria mosquito, Anopheles gambiae, is transstadially transmitted from larvae to adults (both females and males), and whether immune stimulation in the hemocoel as a larva alters development or biological traits of the adult...
October 27, 2017: Journal of Invertebrate Pathology
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