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Thuy Tran

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https://www.readbyqxmd.com/read/28265566/whole-genome-characteristics-and-polymorphic-analysis-of-vietnamese-rice-landraces-as-a-comprehensive-information-resource-for-marker-assisted-selection
#1
Hien Trinh, Khoa Truong Nguyen, Lam Van Nguyen, Huy Quang Pham, Can Thu Huong, Tran Dang Xuan, La Hoang Anh, Mario Caccamo, Sarah Ayling, Nguyen Thuy Diep, Cuong Nguyen, Khuat Huu Trung, Tran Dang Khanh
Next generation sequencing technologies have provided numerous opportunities for application in the study of whole plant genomes. In this study, we present the sequencing and bioinformatic analyses of five typical rice landraces including three indica and two japonica with potential blast resistance. A total of 688.4 million 100 bp paired-end reads have yielded approximately 30-fold coverage to compare with the Nipponbare reference genome. Among them, a small number of reads were mapped to both chromosomes and organellar genomes...
2017: International Journal of Genomics
https://www.readbyqxmd.com/read/28262525/sesquiterpene-derivatives-from-marine-sponge-smenospongia-cerebriformis-and-their-anti-inflammatory-activity
#2
Phan Van Kiem, Le Thi Huyen, Dan Thuy Hang, Nguyen Xuan Nhiem, Bui Huu Tai, Hoang Le Tuan Anh, Pham Van Cuong, Tran Hong Quang, Chau Van Minh, Nguyen Van Dau, Young-A Kim, Lalita Subedi, Sun Yeou Kim, Seung Hyun Kim
Using various chromatographic methods, five new sesquiterpene derivatives named smenohaimiens A-E (1-5) and five known, 19-hydroxy-polyfibrospongol B (6), ilimaquinone (7), dictyoceratin C (8), polyfibrospongol A (9), and polyfibrospongol B (10) were isolated from the marine sponge Smenospongia cerebriformis Duchassaing & Michelotti, 1864. Their structures were assigned by 1D, 2D NMR spectroscopic analysis, HR ESI MS, and calculations of the electron circular dichroism spectra. All compounds were evaluated for the inhibitory activity against NO production in lipopolysaccharide-stimulated in BV2 microglia cells...
April 1, 2017: Bioorganic & Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/28258574/aquaporins-in-the-eye
#3
Thuy Linh Tran, Steffen Hamann, Steffen Heegaard
The major part of the eye consists of water . Continuous movement of water and ions between the ocular compartments and to the systemic circulation is pivotal for many physiological functions in the eye. The movement of water facilitates removal of the many metabolic products of corneal-, ciliary body-, lens- and retinal metabolism, while maintaining transparency in the optical compartments. Transport across the corneal epithelium and endothelium maintains the corneal transparency. Also, aqueous humour is continuously secreted by the epithelia of the ciliary body and maintains the intraocular pressure...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28237481/20-hydroxyecdysone-from-dacrycarpus-imbricatus-bark-inhibits-the-proliferation-of-acute-myeloid-leukemia-cells
#4
Trinh Thi Thuy, Nguyen Thanh Tam, Nguyen Thi Hoang Anh, Dang Viet Hau, Dinh Thi Phong, Le Quoc Thang, Sabrina Adorisio, Tran Van Sung, Domenico V Delfino
OBJECTIVE: To investigate the anti-proliferative effects of 20-hydroxyecdysone isolated from the bark of Dacrycarpus imbricatus (Blume) de Laub. METHODS: Column chromatography was used for isolation of compounds from plant material. The structure of the isolated compound was identified by mass spectrometry and nuclear magnetic resonance techniques, including HSQC, HMBC, NOE-difference experiments. The isolated compound was tested for its anti-proliferative activity in acute myeloid leukemia (AML) and OCI-AML cells...
February 2017: Asian Pacific Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28230242/routine-port-site-excision-in-incidentally-discovered-gallbladder-cancer-is-not-associated-with-improved-survival-a-multi-institution-analysis-from-the-us-extrahepatic-biliary-malignancy-consortium
#5
Cecilia G Ethun, Lauren M Postlewait, Nina Le, Timothy M Pawlik, George Poultsides, Thuy Tran, Kamran Idrees, Chelsea A Isom, Ryan C Fields, Bradley A Krasnick, Sharon M Weber, Ahmed Salem, Robert C G Martin, Charles R Scoggins, Perry Shen, Harveshp D Mogal, Carl Schmidt, Eliza Beal, Ioannis Hatzaras, Rivfka Shenoy, Kenneth Cardona, Shishir K Maithel
BACKGROUND: Current data on the utility of port-site excision (PSE) during re-resection for incidentally discovered gallbladder cancer (IGBC) in the US are conflicting and limited to single-institution series. METHODS: All patients with IGBC who underwent curative re-resection at 10 institutions from 2000 to 2015 were included. Patients with and without PSE were compared. Primary outcome was overall survival (OS). RESULTS: Of 449 pts with GBC, 266 were incidentally discovered, of which 193(73%) underwent curative re-resection and had port-site data; 47 pts(24%) underwent PSE, 146(76%) did not...
February 23, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28221911/molecular-subtyping-and-source-attribution-of-campylobacter-isolated-from-food-animals
#6
Gregory H Tyson, Heather P Tate, Jason Abbott, Thu-Thuy Tran, Claudine Kabera, Emily Crarey, Shenia Young, Patrick F McDERMOTT, Grisselle Sprague, Mark Campbell, Oyewole Adeyemo, Johnette Browne-Silva, Michael Myers, Sutawee Thitaram, Shaohua Zhao
Campylobacter spp. commonly cause gastrointestinal illness in humans. Poultry meats have long been considered the predominant source of these infections, but few in-depth Campylobacter source attribution studies have been completed. We analyzed more than 1,300 Campylobacter isolates recovered from a number of animal and food sources, including dairy and beef cattle, pigs, poultry, and retail poultry meat, and compared them with Campylobacter isolates recovered from human clinical samples. Each isolate was subtyped using pulsed-field gel electrophoresis (PFGE) with SmaI and queried against the Centers for Disease Control and Prevention PulseNet database to identify human isolates with indistinguishable patterns...
November 2016: Journal of Food Protection
https://www.readbyqxmd.com/read/28213314/emerging-themes-of-regulation-at-the-golgi
#7
REVIEW
Stefanie L Makowski, Thuy Tt Tran, Seth J Field
The Golgi is generally recognized for its central role in the secretory pathway to orchestrate protein post-translational modification and trafficking of proteins and lipids to their final destination. Despite the common view of the Golgi as an inert sorting organelle, emerging data demonstrate that important signaling events occur at the Golgi, including those that regulate the trafficking function of the Golgi. The phosphatidylinositol-4-phosphate/GOLPH3/MYO18A/F-actin complex serves as a hub for signals that regulate Golgi trafficking function...
February 14, 2017: Current Opinion in Cell Biology
https://www.readbyqxmd.com/read/28198682/molecular-epidemiology-and-antimicrobial-resistance-phenotypes-of-acinetobacter-baumannii-isolated-from-patients-in-three-hospitals-in-southern-vietnam
#8
Nguyen Tuan Anh, Tran Vu Thieu Nga, Huynh Minh Tuan, Nguyen Si Tuan, Dao Minh Y, Nguyen Van Vinh Chau, Stephen Baker, Ho Huynh Thuy Duong
Multidrug resistance in the nosocomial pathogen Acinetobacter baumannii limits therapeutic options and impacts on clinical care. Resistance against carbapenems, a group of last-resort antimicrobials for treating multidrug-resistant (MDR) A. baumannii infections, is associated with the expression (and over-expression) of carbapenemases encoded by the blaOXA genes. The aim of this study was to determine the prevalence of antimicrobial-resistant A. baumannii associated with infection in three hospitals in southern Vietnam and to characterize the genetic determinants associated with resistance against carbapenems...
January 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28178115/prevalence-of-and-risk-factors-for-oral-human-papillomavirus-infection-with-multiple-genotypes-in-the-united-states
#9
Thanh Cong Bui, Ly Thi-Hai Tran, Thuy Nhu Thai, Sanjay S Shete, Damon J Vidrine, Erich M Sturgis
BACKGROUND: This study investigated the prevalence of and risk factors for oral human papillomavirus (HPV) infection with multiple genotypes in the United States. METHODS: Data were from the nationally representative 2009-2012 National Health and Nutrition Examination Survey. This analysis comprised 9257 participants for whom data on oral HPV (37 genotypes) and associated risk factors were available. RESULTS: The weighted prevalence of multitype (2-6 types) oral HPV infection was 1...
March 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28146608/neuroendocrine-liver-metastasis-the-chance-to-be-cured-after-liver-surgery
#10
Fabio Bagante, Gaya Spolverato, Katiuscha Merath, Lauren McLendon Postlewait, George A Poultsides, Matthew G Mullen, Todd W Bauer, Ryan C Fields, Jorge Lamelas, Hugo P Marques, Luca Aldrighetti, Thuy Tran, Shishir K Maithel, Timothy M Pawlik
BACKGROUND AND OBJECTIVE: Neuroendocrine liver metastasis tumors (NELM) are a heterogeneous group of neoplasms with varied histologic features and a wide range of clinical behaviors. We aimed to identify the fraction of patients cured after liver surgery for NELM. METHODS: Cure fraction models were used to analyze 376 patients who underwent hepatectomy with curative intent for NELM. RESULTS: The median and 5-year disease-free survival (DFS) were 4...
February 1, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28139287/depletion-rate-of-hydrogen-peroxide-from-sodium-perborate-bleaching-agent
#11
Liliann Tran, Rebecca Orth, Peter Parashos, Ying Tao, Calvin W J Tee, Vineet Thenalil Thomas, Georgina Towers, Diem Thuy Truong, Cynthia Vinen, Eric C Reynolds
INTRODUCTION: Internal bleaching of discolored teeth uses sodium perborate reacting with water to form the active agent, hydrogen peroxide (H2O2). Sodium perborate is replaced at varying time intervals depending on clinician preference and until esthetically acceptable results are achieved, but this is done without scientific basis. This study measured the depletion rate of hydrogen peroxide from sodium perborate as a bleaching agent. METHODS: Two sodium perborate bleaching products (Odontobleach [Australian Dental Manufacturing, Kenmore Hills, Queensland, Australia] and Endosure Perborate Micro [Dentalife, Ringwood, Victoria, Australia]) and distilled deionized water mixtures at ratios of 25 μg/mL, 50 μg/mL, and 100 μg/mL were placed into sealed microtubes and incubated at 37°C...
March 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28137815/k13-propeller-mutations-in-plasmodium-falciparum-populations-in-malaria-endemic-regions-of-vietnam-from-2009-to-2016
#12
Nguyen Thuy-Nhien, Nguyen Kim Tuyen, Nguyen Thanh Tong, Tuong Vy, Ngo Viet Thanh, Huynh Thuy Van, Pham Huong-Thu, Huynh Hong Quang, Maciej F Boni, Christiane Dolecek, Jeremy Farrar, Guy E Thwaites, Olivo Miotto, Nicholas J White, Tran Tinh Hien
The spread of artemisinin resistant P. falciparum compromises the therapeutic efficacy of artemisinin combination therapies (ACT) and is considered the greatest threat to current global initiatives to control and eliminate malaria. This is particularly relevant for Vietnam, where dihydroartemisinin-piperaquine (DP) is the recommended ACT for P. falciparum The propeller domain gene of K13, a molecular marker of artemisinin resistance, was sequenced successfully in 1060 P. falciparum isolates collected at 3 malaria hotspots in Vietnam between 2009 and 2016...
January 30, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28133745/technical-note-development-of-a-combined-molecular-breast-imaging-ultrasound-system-for-diagnostic-evaluation-of-mbi-detected-lesions
#13
Michael K O'Connor, Melissa M Morrow, Thuy Tran, Carrie B Hruska, Amy L Conners, Katie N Hunt
PURPOSE: The purpose of this study was to perform a pilot evaluation of an integrated molecular breast imaging/ultrasound (MBI/US) system designed to enable, in real-time, the registration of US to MBI and diagnostic evaluation of breast lesions detected on MBI. METHODS: The MBI/US system was constructed by modifying an existing dual-head cadmium zinc telluride (CZT)-based MBI gamma camera. The upper MBI detector head was replaced with a mesh panel, which allowed an ultrasound probe to access the breast...
February 2017: Medical Physics
https://www.readbyqxmd.com/read/28133477/early-diagnosis-of-helicobacter-pylori-infection-in-vietnamese-patients-with-acute-peptic-ulcer-bleeding-a-prospective-study
#14
Duc Trong Quach, Mai Ngoc Luu, Toru Hiyama, Thuy-HuongThi To, Quy Nhuan Bui, Tuan Anh Tran, Binh Duy Tran, Minh-Cong Hong Vo, Shinji Tanaka, Naomi Uemura
Aims. To investigate H. pylori infection rate and evaluate a combined set of tests for H. pylori diagnosis in Vietnamese patients with acute peptic ulcer bleeding (PUD). Methods. Consecutive patients with acute PUB were enrolled prospectively. Rapid urease test (RUT) with 3 biopsies was carried out randomly. Patients without RUT or with negative RUT received urea breath test (UBT) and serological and urinary H. pylori antibody tests. H. pylori was considered positive if RUT or any noninvasive test was positive...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28106271/mapping-the-intermediate-digestion-phases-of-human-healthy-intestinal-contents-from-distal-ileum-and-caecum-at-fasted-and-fed-state-conditions
#15
Thuy Tran, Dimitrios G Fatouros, Maria Vertzoni, Christos Reppas, Anette Müllertz
OBJECTIVES: To investigate at the ultrastructural level, the colloidal phases formed in the lumen of the distal ileum and caecum of healthy adults. METHODS: Cryogenic transmission electron microscopy (Cryo-TEM) was employed to image the intermediate colloidal phases of human intestinal contents collected from distal ileum and caecum of two healthy volunteers under fasted and fed state conditions. KEY FINDINGS: In samples collected both in the fasted and fed states, Cryo-TEM study revealed the presence of large spherical unilamellar and occasionally bi-lamellar and oligolamellar vesicles with diameters ranging from 50 to 200 nm for both volunteers in distal ileum and caecum...
March 2017: Journal of Pharmacy and Pharmacology
https://www.readbyqxmd.com/read/28103401/maintenance-and-reach-of-exposure-psychotherapy-for-posttraumatic-stress-disorder-18-months-after-training
#16
Craig S Rosen, Afsoon Eftekhari, Jill J Crowley, Brandy N Smith, Eric Kuhn, Lindsay Trent, Nicole Martin, Thuy Tran, Josef I Ruzek
This study examined aspects of clinicians' work environment that facilitated sustained use of prolonged exposure (PE) therapy. Surveys were completed by 566 U.S. Department of Veterans Affairs clinicians 6 and 18 months after intensive training in PE. The number of patients treated with PE at 18 months (reach) was modeled as a function of clinician demographics, clinician beliefs about PE, and work context factors. There were 342 clinicians (60.4%) who used PE at 6 and 18 months after training, 58 (10.2%) who used PE at 18 but not 6 months, 95 (16...
February 2017: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/28098263/a-lab-on-a-chip-for-monolith-based-preconcentration-and-electrophoresis-separation-of-phosphopeptides
#17
Monica Araya-Farias, Szymon Dziomba, Benjamin Carbonnier, Mohamed Guerrouache, Ichraf Ayed, Nacera Aboud, Myriam Taverna, N Thuy Tran
A microdevice combining online preconcentration and separation of phosphopeptides was developed in a glass microchip. An ethylene glycol methacrylate phosphate (EGMP), acrylamide (AM) and bisacrylamide (BAA) based monolith was synthesized within microchannels through a photo-driven process. Morphological investigations revealed a homogeneous monolithic structure composed of uniform nodules (∼0.8 μm), with a large pore volume (0.62 cm(3) g(-1)) and sufficiently high specific surface area (34.1 m(2) g(-1))...
January 18, 2017: Analyst
https://www.readbyqxmd.com/read/28088276/solid-supports-for-extraction-and-preconcentration-of-proteins-and-peptides-in-microfluidic-devices-a-review
#18
REVIEW
Szymon Dziomba, Monica Araya-Farias, Claire Smadja, Myriam Taverna, Benjamin Carbonnier, N Thuy Tran
Determination of proteins and peptides is among the main challenges of today's bioanalytical chemistry. The application of microchip technology in this field is an exhaustively developed concept that aims to create integrated and fully automated analytical devices able to quantify or detect one or several proteins from a complex matrix. Selective extraction and preconcentration of targeted proteins and peptides especially from biological fluids is of the highest importance for a successful realization of these microsystems...
February 22, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28086775/rapid-decline-in-the-susceptibility-of-plasmodium-falciparum-to-dihydroartemisinin-piperaquine-in-the-south-of-vietnam
#19
Ngo Viet Thanh, Nguyen Thuy-Nhien, Nguyen Thi Kim Tuyen, Nguyen Thanh Tong, Nguyen Thuy Nha-Ca, Le Thanh Dong, Huynh Hong Quang, Jeremy Farrar, Guy Thwaites, Nicholas J White, Marcel Wolbers, Tran Tinh Hien
BACKGROUND: Artemisinin resistant Plasmodium falciparum has emerged in the countries of the Greater Mekong sub-region posing a serious threat to global malaria elimination efforts. The relationship of artemisinin resistance to treatment failure has been unclear. METHODS: In annual studies conducted in three malaria endemic provinces in the south of Vietnam (Binh Phuoc, Ninh Thuan and Gia Lai) between 2011 and 2015, 489 patients with uncomplicated P. falciparum malaria were enrolled in detailed clinical, parasitological and molecular therapeutic response assessments with 42 days follow up...
January 13, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28072531/discovery-of-2-1r-4r-4-4-chlorophenyl-phenyl-carbamoyl-oxy-methyl-cyclohexyl-methoxy-acetate-ralinepag-an-orally-active-prostacyclin-receptor-agonist-for-the-treatment-of-pulmonary-arterial-hypertension
#20
Thuy-Anh Tran, Bryan Kramer, Young-Jun Shin, Pureza Vallar, P Douglas Boatman, Ning Zou, Carleton R Sage, Tawfik Gharbaoui, Ashwin Krishnan, Biman Pal, Sagar R Shakya, Antonio Garrido Montalban, John W Adams, Juan Ramirez, Dominic P Behan, Anna Shifrina, Anthony Blackburn, Tina Leakakos, Yunqing Shi, Michael Morgan, Abu Sadeque, Weichao Chen, David J Unett, Ibragim Gaidarov, Xiaohua Chen, Steve Chang, Hsin-Hui Shu, Shiu-Feng Tung, Graeme Semple
The design and synthesis of a new series of potent non-prostanoid IP receptor agonists that showed oral efficacy in the rat monocrotaline model of pulmonary arterial hypertension (PAH) are described. Detailed profiling of a number of analogues resulted in the identification of 5c (ralinepag) that has good selectivity in both binding and functional assays with respect to most members of the prostanoid receptor family and a more modest 30- to 50-fold selectivity over the EP3 receptor. In our hands, its potency and efficacy are comparable or superior to MRE269 (the active metabolite of the clinical compound NS-304) with respect to in vitro IP receptor dependent cAMP accumulation assays...
February 9, 2017: Journal of Medicinal Chemistry
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