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https://www.readbyqxmd.com/read/28935616/endocrine-disruptors-and-health-effects-in-africa-a-call-for-action
#1
Maria S Bornman, Natalie H Aneck-Hahn, Christiaan de Jager, Gesina M Wagenaar, Hindrik Bouwman, Irene E J Barnhoorn, Sean M Patrick, Laura N Vandenberg, Andreas Kortenkamp, Bruce Blumberg, Sarah Kimmins, Bernard Jegou, Jacques Auger, Joseph DiGangi, Jerrold J Heindel
BACKGROUND: Africa faces a number of unique environmental challenges. Unfortunately, it lacks the infrastructure needed to support the comprehensive environmental studies that could provide the scientific basis to inform environmental policies. There are a number of known sources of endocrine-disrupting chemicals (EDCs) and other hazardous chemicals in Africa. However, a coordinated approach to identify and monitor these contaminants and to develop strategies for public health interventions has not yet been made...
August 22, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/28932363/cadmium-toxicity-and-treatment-an-update
#2
REVIEW
Mehrdad Rafati Rahimzadeh, Mehravar Rafati Rahimzadeh, Sohrab Kazemi, Ali-Akbar Moghadamnia
Cadmium poisoning has been reported from many parts of the world. It is one of the global health problems that affect many organs and in some cases it can cause deaths annually. Long-term exposure to cadmium through air, water, soil, and food leads to cancer and organ system toxicity such as skeletal, urinary, reproductive, cardiovascular, central and peripheral nervous, and respiratory systems. Cadmium levels can be measured in the blood, urine, hair, nail and saliva samples. Patients with cadmium toxicity need gastrointestinal tract irrigation, supportive care, and chemical decontamination traditional-based chelation therapy with appropriate new chelating agents and nanoparticle-based antidotes...
2017: Caspian Journal of Internal Medicine
https://www.readbyqxmd.com/read/28928940/comparison-of-color-discrimination-in-chronic-heavy-smokers-and-healthy-subjects
#3
Thiago Monteiro de Paiva Fernandes, Natalia Leandro Almeida, Natanael Antonio Dos Santos
Background: Cigarette smoke is probably the most significant source of exposure to toxic chemicals for humans, involving health-damaging components, such as nicotine, hydrogen cyanide and formaldehyde. The aim of the present study was to assess the influence of chronic heavy smoking on color discrimination (CD). Methods: All subjects were free of any neuropsychiatric disorder, identifiable ocular disease and had normal acuity. No abnormalities were detected in the fundoscopic examination and in the optical coherence tomography exam...
2017: F1000Research
https://www.readbyqxmd.com/read/28923343/association-among-total-serum-isomers-of-perfluorinated-chemicals-glucose-homeostasis-lipid-profiles-serum-protein-and-metabolic-syndrome-in-adults-nhanes-2013-2014
#4
Hui-Shan Liu, Li-Li Wen, Pei-Lun Chu, Chien-Yu Lin
Perfluorinated chemicals (PFCs) have been used widely in consumer products manufacture. Recent in vitro as well as animal studies have found that there are different toxicity and pharmacokinetic profiles between isomers of perfluorooctanoic acid (PFOA) and/or perfluorooctane sulfonate (PFOS). However, the differential effects of linear or branched PFOA/PFOS isomers on human beings have never been reported. Herein, we examined 1871 adult subjects (age older than 18 years) from the National Health and Nutrition Examination Survey (NHANES) 2013-2014 to determine the association between the isomers of PFOA/PFOS and serum biochemistry profiles, including glucose, lipids, protein and components of metabolic syndrome (MS)...
September 15, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28922028/analysis-of-aflatoxin-m1-in-breast-milk-and-its-association-with-nutritional-and-socioeconomic-status-of-lactating-mothers-in-lebanon
#5
Jomana Elaridi, Maya Bassil, Joelle Abi Kharma, Farah Daou, Hussein F Hassan
Aflatoxin B1 (AFB1) is the most potent of the dietary aflatoxins, and its major metabolite, aflatoxin M1 (AFM1), is frequently found in the breast milk of lactating mothers. The aim of this study was to assess the occurrence and factors associated with AFM1 contamination of breast milk collected from lactating mothers in Lebanon. A total of 111 breast milk samples were collected according to the guidelines set by the World Health Organization. Samples were analyzed with a competitive enzyme-linked immunosorbent assay between December 2015 and November 2016...
September 18, 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28913333/utilization-of-parenteral-morphine-by-application-of-atc-ddd-methodology-retrospective-study-in-the-referral-teaching-hospital
#6
Viktorija Dragojevic-Simic, Nemanja Rancic, Dusica Stamenkovic, Radoje Simic
BACKGROUND: Few studies analyzed the pattern of opioid analgesic utilization in hospital settings. The aim of this study was to determine the consumption pattern of parenteral morphine in patients hospitalized in the Serbian referral teaching hospital and to correlate it with utilization at the national and international level. METHODS: In retrospective study, the required data were extracted from medical records of surgical patients who received parenteral morphine in the 5-year period, from 2011 to 2015...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28901325/associations-between-socio-demographic-characteristics-and-chemical-concentrations-contributing-to-cumulative-exposures-in-the-united-states
#7
Hongtai Huang, Rogelio Tornero-Velez, Timothy M Barzyk
Association rule mining (ARM) has been widely used to identify associations between various entities in many fields. Although some studies have utilized it to analyze the relationship between chemicals and human health effects, fewer have used this technique to identify and quantify associations between environmental and social stressors. Socio-demographic variables were generated based on U.S. Census tract-level income, race/ethnicity population percentage, education level, and age information from the 2010-2014, 5-Year Summary files in the American Community Survey (ACS) database, and chemical variables were generated by utilizing the 2011 National-Scale Air Toxics Assessment (NATA) census tract-level air pollutant exposure concentration data...
September 13, 2017: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/28886960/-indoor-air-quality-and-parents-of-asthmatic-children-practices
#8
S Larramendy Magnin, B Desssome, L Moret
BACKGROUND: Indoor air pollution can worsen asthma in children. Better knowledge of factors determining parents' reception of recommendations to limit pollution of indoor air in the homes of asthmatic children would be helpful to improve implementation. METHOD: A descriptive study evaluating practices known to have an impact on the quality of air in homes was conducted among parents of asthmatic children aged 3 to 16 years. From May to September 2013, parents answered anonymous self-administered questionnaires in waiting rooms of generalist practitioners, in the Nantes University pneumology pediatric outpatient clinic, and as part of therapeutic education sessions conducted by the Asthma-44 Network...
September 5, 2017: Revue D'épidémiologie et de Santé Publique
https://www.readbyqxmd.com/read/28878428/elimination-of-guinea-worm-disease-in-ethiopia-current-status-of-the-disease-s-eradication-strategies-and-challenges-to-the-end-game
#9
Habtamu Bedimo Beyene, Abyot Bekele, Amanu Shifara, Yehenew A Ebstie, Zelalem Desalegn, Zeyede Kebede, Abate Mulugeta, Kebede Deribe, Zerihun Tadesse, Tamrat Abebe, Biruck Kebede, Getaneh Abrha, Daddi Jima
Dracunculiasis, also named Guinea Worm Disease (GWD), is one of the Neglected Tropical Diseases (NTDs) caused by a parasitic nematode known as Dracunculus medinensis and has been known since antiquity as 'fiery serpent' from Israelites. It is transmitted to humans via drinking contaminated water containing infective copepods. Given, its feasibility for eradication, the Guinea Worm Eradication Program (GWEP) was launched in 1980 with the aim of eradicating the disease. Since its inception, GWEP has made an extraordinary progress in interrupting transmission...
2017: Ethiopian Medical Journal
https://www.readbyqxmd.com/read/28871819/cyanide-poisoning-in-thailand-before-and-after-establishment-of-the-national-antidote-project
#10
Sahaphume Srisuma, Aimon Pradoo, Panee Rittilert, Sunun Wongvisavakorn, Achara Tongpoo, Charuwan Sriapha, Wannapa Krairojananan, Netnapis Suchonwanich, Sumana Khomvilai, Winai Wananukul
CONTEXT: Antidote shortage is a global problem. In Thailand, the National Antidote Project (NAP) has operated since November 2010 to manage the national antidote stockpile, educate the healthcare providers on appropriate antidote use, and evaluate antidote usage. OBJECTIVE: To evaluate the effect of NAP implementation on mortality rate and antidote use in cyanide poisoning cases arising from ingestion of cyanide or cyanogenic glycoside. METHODS: This is a retrospective cohort of poisoning cases involving cyanide or cyanogenic glycoside ingestion reported to Ramathibodi Poison Center from 1 January 2007 to 31 December 2015...
September 5, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28843527/factors-associated-with-the-trend-of-physical-and-chemical-restraint-use-among-long-term-care-facility-residents-in-hong-kong-data-from-an-11-year-observational-study
#11
Kuen Lam, Joseph S K Kwan, Chi Wai Kwan, Alice M L Chong, Claudia K Y Lai, Vivian W Q Lou, Angela Y M Leung, Justina Y W Liu, Xue Bai, Iris Chi
BACKGROUND: Negative effects of restraint use have been well-documented. However, the prevalence of restraints use has been high in long-term care facilities in Hong Kong compared with other countries and this goes against the basic principles of ethical and compassionate care for older people. The present study aimed to review the change in the prevalence of physical and chemical restraint use in long-term care facilities (LTCFs) over a period of 11 years in Hong Kong and to identify the major factors associated with their use...
August 23, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28821010/willingness-to-pay-for-safe-drinking-water-a-contingent-valuation-study-in-jacksonville-fl
#12
Chiradip Chatterjee, Russell Triplett, Christopher K Johnson, Parvez Ahmed
A surprising number of U.S. cities have drinking water with unhealthy levels of chemicals and contaminants. The city of Jacksonville (Florida), the location for this study, owns the dubious distinction of being ranked among the worst major American cities in water quality according to water quality tests conducted between 2005 and 2009 by the Environmental Working Group (EWG). This report of toxic chemicals in the Jacksonville water supply generated considerable negative publicity and coincides with a frequent and common complaint among residents of foul-smelling water...
August 15, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28819080/a-survey-on-selection-use-maintenance-and-management-of-chemical-protective-gloves-at-workplaces-in-japan
#13
Isamu Kabe, Hiroko Tsuruoka, Takeshi Kochi, Yasuo Koga, Masafumi Eguchi, Tomomi Matsui, Rie Ito, Yoko Tokujitani, Hiroyuki Miyauchi, Shigeru Tanaka
OBJECTIVES: The aim of this study was to survey the selection, use, and maintenance of chemical protective gloves (CPGs) at real workplaces. METHODS: Subjects comprised 817 workers using CPGs at seven domestic manufacturing plants in Japan. We administered an anonymous questionnaire survey comprising the following aspect related to CPGs: environment of use, conditions of use, method of selection, knowledge/awareness pertaining to their use, method of use, precautionary measures associated with their use, maximum time of use, and maintenance...
August 17, 2017: Sangyō Eiseigaku Zasshi, Journal of Occupational Health
https://www.readbyqxmd.com/read/28818300/birth-outcome-racial-disparities-a-result-of-intersecting-social-and-environmental-factors
#14
Heather H Burris, Michele R Hacker
Adverse birth outcomes such as preterm birth, low-birth weight, and infant mortality continue to disproportionately affect black and poor infants in the United States. Improvements in healthcare quality and access have not eliminated these disparities. The objective of this review was to consider societal factors, including suboptimal education, income inequality, and residential segregation, that together lead to toxic environmental exposures and psychosocial stress. Many toxic chemicals, as well as psychosocial stress, contribute to the risk of adverse birth outcomes and black women often are more highly exposed than white women...
August 14, 2017: Seminars in Perinatology
https://www.readbyqxmd.com/read/28808479/a-multiscale-model-for-the-world-s-first-parasitic-disease-targeted-for-eradication-guinea-worm-disease
#15
Rendani Netshikweta, Winston Garira
Guinea worm disease (GWD) is both a neglected tropical disease and an environmentally driven infectious disease. Environmentally driven infectious diseases remain one of the biggest health threats for human welfare in developing countries and the threat is increased by the looming danger of climate change. In this paper we present a multiscale model of GWD that integrates the within-host scale and the between-host scale. The model is used to concurrently examine the interactions between the three organisms that are implicated in natural cases of GWD transmission, the copepod vector, the human host, and the protozoan worm parasite (Dracunculus medinensis), and identify their epidemiological roles...
2017: Computational and Mathematical Methods in Medicine
https://www.readbyqxmd.com/read/28805534/health-behaviors-related-to-endocrine-disrupting-chemicals-and-the-associated-factors-of-adolescent-korean-girls
#16
SoMi Park, ChaeWeon Chung
In this cross-sectional study, we examined the relationships among knowledge about endocrine-disrupting chemicals (EDCs), recognition of EDCs-related female reproductive illnesses, concern for the environment, perceived susceptibility to EDCs-related diseases, self- appraisal of exposure to EDCs, and health behaviors related to EDCs in adolescent Korean girls. A convenience sample of 218 girls was recruited during July and August 2015 from middle and high schools located in a city in Korea. The self-administered questionnaire incorporated four characteristics of the participants, five related factors, and a dependent variable of health behaviors...
August 14, 2017: Women & Health
https://www.readbyqxmd.com/read/28781892/inflammatory-markers-are-positively-associated-with-serum-trans-fatty-acids-in-an-adult-american-population
#17
Mohsen Mazidi, Hong-Kai Gao, Andre Pascal Kengne
BACKGROUND AND AIM: The relationship between serum trans-fatty acids (TFAs) and systemic inflammation markers is unclear. We investigated the association of serum TFAs with high sensitivity C-reactive protein (hs-CRP) and fibrinogen in adult Americans. METHODS: The 1999 to 2000 National Health and Nutrition Examination Survey (NHANES) participants with measured data on hs-CRP and fibrinogen were included. TFAs were measured via capillary gas chromatography and mass spectrometry using negative chemical ionization...
2017: Journal of Nutrition and Metabolism
https://www.readbyqxmd.com/read/28774628/trihalomethane-concentrations-in-tap-water-as-determinant-of-bottled-water-use-in-the-city-of-barcelona
#18
Laia Font-Ribera, Jordi Colomer Cotta, Anna Gómez-Gutiérrez, Cristina M Villanueva
Bottled water consumption is increasing worldwide, despite its huge economic and environmental cost. We aim to describe personal and tap water quality determinants of bottled water use in the city of Barcelona. This cross-sectional study used data from the Health Survey of Barcelona in 2006 (N=5417 adults). The use of bottled water to drink and to cook was evaluated in relation to age, gender, educational level, district and levels of trihalomethanes (THMs), free chlorine, conductivity, chloride, sodium, pH, nitrate and aluminium in municipal tap water using Robust Poisson Regression...
August 2017: Journal of Environmental Sciences (China)
https://www.readbyqxmd.com/read/28761934/metabolic-fingerprints-from-the-human-oral-microbiome-reveal-a-vast-knowledge-gap-of-secreted-small-peptidic-molecules
#19
Anna Edlund, Neha Garg, Hosein Mohimani, Alexey Gurevich, Xuesong He, Wenyuan Shi, Pieter C Dorrestein, Jeffrey S McLean
Recent research indicates that the human microbiota play key roles in maintaining health by providing essential nutrients, providing immune education, and preventing pathogen expansion. Processes underlying the transition from a healthy human microbiome to a disease-associated microbiome are poorly understood, partially because of the potential influences from a wide diversity of bacterium-derived compounds that are illy defined. Here, we present the analysis of peptidic small molecules (SMs) secreted from bacteria and viewed from a temporal perspective...
July 2017: MSystems
https://www.readbyqxmd.com/read/28761027/five-year-epidemiological-trends-for-chemical-poisoning-in-jeddah-saudi-arabia
#20
Sami Hamdan Alzahrani, Nahla Khamis Ibrahim, Mohammed Abdel Elnour, Ali Hassan Alqahtani
BACKGROUND: Poisoning is a significant global public health challenge in terms of morbidity and mortality. We conducted this study because of the lack of large population-based studies on chemical poisoning in Saudi Arabia. OBJECTIVE: Describe epidemiological trends, associated factors, and outcomes of chemical poisoning cases reported to the Jeddah Health Affairs Directorate, Saudi Arabia. DESIGN: Descriptive, retrospective medical record review...
July 2017: Annals of Saudi Medicine
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