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Appropriateness criterion

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https://www.readbyqxmd.com/read/29222568/model-driven-treatment-of-childhood-apraxia-of-speech-positive-effects-of-the-speech-motor-learning-approach
#1
Anita van der Merwe, Mollie Steyn
Purpose: The aim of the study was to propose the speech motor learning approach (Van der Merwe, 2011) as a treatment for childhood apraxia of speech and to determine if it will effect positive change in the ability of a 33-month-old child to produce untreated nonwords and words containing treated age-appropriate consonants (Set 1 sounds), untreated age-appropriate consonants (Set 2), and untreated age-inappropriate consonants (Set 3) and also to determine the nature and number of segmental speech errors before and after treatment...
December 8, 2017: American Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/29221713/effect-of-grass-sublingual-tablet-immunotherapy-is-similar-in-children-and-adults-a-bayesian-approach-to-design-pediatric-sublingual-immunotherapy-trials
#2
Amarjot Kaur, David Skoner, Joseph Ibrahim, Qing Li, Richard F Lockey, Michael Blaiss, Albrecht Bufe, Jens Strodl Andersen, Giorgio Walter Canonica, Hendrik Nolte
BACKGROUND: Large sample sizes are needed for sublingual immunotherapy (SLIT) trials due to inherent data variability secondary to inconsistent allergen exposure. Obtaining large sample sizes for pediatric SLIT trials is challenging, but a Bayesian approach using prior adult data can reduce the necessary sample size. OBJECTIVE: To describe how a Bayesian framework utilizing prior information from adult trials can be used to improve pediatric SLIT clinical development...
December 5, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29216328/comparative-analysis-of-idf-atpiii-and-cds-in-the-diagnosis-of-metabolic-syndrome-among-adult-inhabitants-in-jiangxi-province-china
#3
Lengmei Cheng, Wei Yan, Liping Zhu, Yiying Chen, Jie Liu, Yan Xu, Lu Ji, Junrong He
BACKGROUND: Currently, the prevalence of metabolic syndrome (MS) has attracted widespread public attention. However, there is a war regarding the applicability of the diagnosis in different populations regarding the distinct criteria for the diagnosis of MS. Data about the prevalence rate of MS and its components in Jiangxi Province are limited. Thus, our goals were to compare the consistency rates and applicability of three criteria, i.e., those of the International Diabetes Federation (IDF), the National Cholesterol Education Program Adult Treatment PanelⅢ (ATPⅢ), and the Chinese Diabetes Society (CDS)...
2017: PloS One
https://www.readbyqxmd.com/read/29211001/exploring-determinants-of-spatial-variations-in-the-dengue-fever-epidemic-using-geographically-weighted-regression-model-a-case-study-in-the-joint-guangzhou-foshan-area-china-2014
#4
Hongyan Ren, Lan Zheng, Qiaoxuan Li, Wu Yuan, Liang Lu
Dengue fever (DF) is a common and rapidly spreading vector-borne viral disease in tropical and subtropical regions. In recent years, this imported disease has posed an increasing threat to public health in China, especially in many southern cities. Although the severity of DF outbreaks in these cities is generally associated with known risk factors at various administrative levels, spatial heterogeneities of these associations remain little understood on a finer scale. In this study, the neighboring Guangzhou and Foshan (GF) cities were considered as a joint area for characterizing the spatial variations in the 2014 DF epidemic at various grid levels from 1 × 1 km² to 6 × 6 km²...
December 6, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29203319/critical-power-how-different-protocols-and-models-affect-its-determination
#5
Felipe Mattioni Maturana, Federico Y Fontana, Silvia Pogliaghi, Louis Passfield, Juan M Murias
In cycling, critical power (CP) and work above CP (W') can be estimated through linear and nonlinear models. Despite the concept of CP representing the upper boundary of sustainable exercise, overestimations may be made as the models possess inherent limitations and the protocol design is not always appropriate. OBJECTIVES: To measure and compare CP and W' through the exponential (CPexp), 3-parameter hyperbolic (CP3-hyp), 2-parameter hyperbolic (CP2-hyp), linear (CPlinear), and linear 1/time (CP1/time) models, using different combinations of TTE trials of different durations (approximately 1-20min)...
November 29, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/29197108/refining-a-claims-based-algorithm-to-estimate-biologic-medication-effectiveness-and-cost-per-effectively-treated-patient-with-rheumatoid-arthritis
#6
Ryan A Popp, Karen Rascati, Matthew Davis, Ujas Patel
BACKGROUND: Claims data generally lack information on clinical outcomes. However, a validated, claims-based algorithm for estimating effectiveness of biologic agents in treating rheumatoid arthritis (RA) has recently been developed and applied to various databases. OBJECTIVES: The objectives of the study were to implement a claims-based algorithm in a large nationwide database to estimate medication effectiveness and cost for patients with RA using biologic disease-modifying antirheumatic drugs (DMARDs) and to assess the effect of eliminating one criterion from the algorithm on results...
December 1, 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/29194876/rational-decision-making-in-medicine-implications-for-overuse-and-underuse
#7
Benjamin Djulbegovic, Shira Elqayam, William Dale
In spite of substantial spending and resource utilization, today's health care remains characterized by poor outcomes, largely due to overuse (overtesting/overtreatment) or underuse (undertesting/undertreatment) of health services. To a significant extent, this is a consequence of low-quality decision making that appears to violate various rationality criteria. Such suboptimal decision making is considered a leading cause of death and is responsible for more than 80% of health expenses. In this paper, we address the issue of overuse or underuse of health care interventions from the perspective of rational choice theory...
December 1, 2017: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/29191593/outcomes-in-patients-with-aggressive-or-refractory-disease-from-revel-a-randomized-phase-iii-study-of-docetaxel-with-ramucirumab-or-placebo-for-second-line-treatment-of-stage-iv-non-small-cell-lung-cancer
#8
Martin Reck, Luis Paz-Ares, Paolo Bidoli, Federico Cappuzzo, Shaker Dakhil, Denis Moro-Sibilot, Hossein Borghaei, Melissa Johnson, Robert Jotte, Nathan A Pennell, Frances A Shepherd, Anne Tsao, Michael Thomas, Gebra Cuyun Carter, Faye Chan-Diehl, Ekaterine Alexandris, Pablo Lee, Annamaria Zimmermann, Andreas Sashegyi, Maurice Pérol
OBJECTIVES: The REVEL study demonstrated improved efficacy for patients with advanced non-small cell lung cancer treated with ramucirumab plus docetaxel, independent of histology. This exploratory analysis characterized the treatment effect in REVEL patients who were refractory to prior first-line treatment. MATERIALS AND METHODS: Refractory patients had a best response of progressive disease to first-line treatment. Endpoints included overall survival (OS), progression-free survival (PFS), objective response rate (ORR), quality of life (QoL), and safety...
October 2017: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/29191482/multivariate-modeling-of-diffuse-reflectance-infrared-fourier-transform-drift-spectra-of-mixtures-with-low-content-polymorphic-impurities-with-analysis-of-outliers
#9
Slobodan Šašić, Andrew Gilkison, Mark Henson
Diffuse Reflectance Fourier Transform Infrared Spectroscopy (DRIFTS)-based multivariate models were developed to quantify the content of two polymorphic impurities in mixtures with the desired active pharmaceutical ingredient (API) form, with the impurities not exceeding 2% wt/wt. In addition, close attention was paid to the outlier detection criteria: Q residuals; Hotelling T2; and score bi-plot. While reasonably accurate results were obtained for the relatively simple calibration models for both forms of the impurity, the predictions for "blank" samples (separately verified to be impurity-free) were apparently biased...
November 27, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/29189578/validity-of-an-isometric-midthigh-pull-dynamometer-in-male-youth-athletes
#10
Kevin Till, Rhys Morris, Keith Stokes, Grant Trewartha, Craig Twist, Nick Dobbin, Richard Hunwicks, Ben Jones
Till, K, Morris, R, Stokes, K, Trewartha, G, Twist, C, Dobbin, N, Hunwicks, R, and Jones, B. Validity of an isometric midthigh pull dynamometer in male youth athletes. J Strength Cond Res XX(X): 000-000, 2017-The purpose of this study was to investigate the validity of an isometric midthigh pull dynamometer against a criterion measure (i.e., 1,000-Hz force platform) for assessing muscle strength in male youth athletes. Twenty-two male adolescent (age 15.3 ± 0.5 years) rugby league players performed 4 isometric midthigh pull efforts (i...
November 16, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29184806/polycystic-ovary-syndrome-in-adolescence-diagnostic-and-therapeutic-strategies
#11
REVIEW
Manmohan K Kamboj, Andrea E Bonny
Controversy continues about the underlying etiopathogenesis, diagnostic criteria, and recommendations for polycystic ovary syndrome (PCOS) in adolescents. Recent literature has recognized these deficiencies and evidence based expert recommendations have become more available. The purpose of this chapter is to offer primary care providers a practical understanding and approach to the diagnosis and treatment of PCOS in adolescents. Although the presence of polycystic ovary morphology (PCOM) is included as a key diagnostic criterion of PCOS in adults, it is currently not recommended for the diagnosis in adolescents...
October 2017: Translational pediatrics
https://www.readbyqxmd.com/read/29183103/-icf-checklist-to-evaluate-inclusion-of-elderlies-with-intellectual-disability-psychometric-properties
#12
Silvia Queri, Michael Eggart, Maren Wendel, Ulrike Peter
Background An instrument should have been developed to measure participation as one possible criterion to evaluate inclusion of elderly people with intellectual disability. The ICF was utilized, because participation is one part of health related functioning, respectively disability. Furthermore ICF includes environmental factors (contextual factors) and attaches them an essentially influence on health related functioning, in particular on participation. Thus ICF Checklist additionally identifies environmental barriers for elimination...
November 28, 2017: Die Rehabilitation
https://www.readbyqxmd.com/read/29182996/distinguishing-among-multiple-sclerosis-fallers-near-fallers-and-non-fallers
#13
Nora E Fritz, Ani Eloyan, Moira Baynes, Scott D Newsome, Peter A Calabresi, Kathleen M Zackowski
BACKGROUND: Fall rates among adults with multiple sclerosis are consistently greater than 50%, but near-falls (i.e. a trip or stumble) are often undocumented. Furthermore, little is known about the circumstances surrounding fall and near-fall events. The purpose of this study was to examine the similarities and differences among non-fallers, near-fallers and fallers with multiple sclerosis, including the circumstances that surround falls and near-falls. METHODS: In a single visit, 135 multiple sclerosis participants completed the Hopkins Falls Grading Scale, a custom questionnaire investigating circumstances surrounding falls and near-falls, and performed the Timed Up and Go and Timed 25-Foot Walk tests...
November 22, 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29181592/selection-and-qualification-of-simplified-qsp-models-when-using-model-order-reduction-techniques
#14
Chihiro Hasegawa, Stephen B Duffull
Quantitative systems pharmacology (QSP) models are increasingly used in drug development to provide a deep understanding of the mechanism of action of drugs and to identify appropriate disease targets. Such models are, however, not suitable for estimation purposes due to their high dimensionality. Based on any desired and specific input-output relationship, the system may be reduced to a model with fewer states and parameters. However, any simplification process will be a trade-off between model performance and complexity...
November 27, 2017: AAPS Journal
https://www.readbyqxmd.com/read/29163862/comparison-of-dsm-5-and-proposed-icd-11-criteria-for-ptsd-with-dsm-iv-and-icd-10-changes-in-ptsd-prevalence-in-military-personnel
#15
Annika Kuester, Kai Köhler, Thomas Ehring, Christine Knaevelsrud, Louisa Kober, Antje Krüger-Gottschalk, Ingo Schäfer, Julia Schellong, Ulrich Wesemann, Heinrich Rau
Background: Recently, changes have been introduced to the diagnostic criteria for posttraumatic stress disorder (PTSD) according to the Diagnostic and Statistical Manual of Mental Disorders (DSM) and the International Classification of Diseases (ICD). Objectives:This study investigated the effect of the diagnostic changes made from DSM-IV to DSM-5 and from ICD-10 to the proposed ICD-11. The concordance of provisional PTSD prevalence between the diagnostic criteria was examined in a convenience sample of 100 members of the German Armed Forces...
2017: European Journal of Psychotraumatology
https://www.readbyqxmd.com/read/29161300/brca1-and-brca2-mutational-profile-and-prevalence-in-hereditary-breast-and-ovarian-cancer-hboc-probands-from-southern-brazil-are-international-testing-criteria-appropriate-for-this-specific-population
#16
Bárbara Alemar, Cleandra Gregório, Josef Herzog, Camila Matzenbacher Bittar, Cristina Brinckmann Oliveira Netto, Osvaldo Artigalas, Ida Vanessa D Schwartz, Jordy Coffa, Suzi Alves Camey, Jeffrey Weitzel, Patricia Ashton-Prolla
BACKGROUND: Germline pathogenic variants in BRCA1 and BRCA2 (BRCA) are the main cause of Hereditary Breast and Ovarian Cancer syndrome (HBOC). METHODS: In this study we evaluated the mutational profile and prevalence of BRCA pathogenic/likely pathogenic variants among probands fulfilling the NCCN HBOC testing criteria. We characterized the clinical profile of these individuals and explored the performance of international testing criteria. RESULTS: A pathogenic/likely pathogenic variant was detected in 19...
2017: PloS One
https://www.readbyqxmd.com/read/29158955/correlation-of-self-reported-outcome-measures-and-the-selective-functional-movement-assessment-sfma-an-exploration-of-validity
#17
Mark Riebel, Michael Crowell, Jeffrey Dolbeer, Eliza Szymanek, Don Goss
Background/Purpose: The Selective Functional Movement Assessment (SFMA) is a clinical model used to assist diagnosis and treatment of musculoskeletal disorders by identifying dysfunctions in movement patterns. Based on the premise that addressing movement dysfunction is associated with an improvement in patient outcomes, the validity of the SFMA would be strengthened by observed improvement in self-reported function being associated with change in movement patterns. The purpose of this study was to explore the validity of the SFMA by determining if a correlation exists between a change in self-reported outcome measures and attributes of the assessment...
November 2017: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/29158623/criterion-validity-of-the-hrqolisp-e-a-new-context-specific-screening-tool-for-poststroke-depression
#18
Akin Ojagbemi, Mayowa Owolabi, Joshua Akinyemi, Bruce Ovbiagele
Objectives: The optimal tool for identifying postsroke depression (PSD) is yet to be identified. In the present study, we rely on the depression subscale of the Hospital Anxiety and Depression Scale (HADS-D) as a meaningful criterion to investigate the psychometric properties of the HRQOLISP-E, a new context-specific screening tool for PSD developed from a large cross-cultural sample. Methods: We assessed baseline data being collected as part of an intervention to improve one-year blood pressure control among recent (≤one month) stroke survivors...
2017: Behavioural Neurology
https://www.readbyqxmd.com/read/29148838/discordance-between-age-and-size-based-criteria-of-child-passenger-restraint-appropriateness
#19
Mary L Smiley, C Raymond Bingham, Peter D Jacobson, Michelle L Macy
Objectives In this study we sought to accomplish the following objectives: 1) to calculate the percentage of children considered appropriately restrained across eight criteria of increasing restrictiveness; 2) to examine agreement between age- and size-based appropriateness criteria; 3) to assess for changes in the percentage of children considered appropriately restrained by the eight criteria between 2011 (shortly after updates to United States (U.S.) guidelines) and 2015. Methods Data from two cross-sectional surveys of 928 parents of children younger than 12 years old (n = 591 in 2011, n = 337 in 2015) were analyzed in 2017...
November 17, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/29145739/the-development-of-positive-psychology-outcome-measures-and-their-uses-in-dementia-research-a-systematic-review
#20
Charlotte R Stoner, Jacki Stansfeld, Martin Orrell, Aimee Spector
Positive psychology is gaining credence within dementia research but currently there is a lack of outcome measures within this area developed specifically for people with dementia. Authors have begun adopting positive psychology measures developed with other populations but there is no consensus around which are more appropriate or psychometrically robust. A systematic search identified measures used between 1998 and 2017 and an appraisal of the development procedure was undertaken using standardised criteria enabling the awarding of scores based on reporting of psychometric information...
January 1, 2017: Dementia
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