keyword
https://read.qxmd.com/read/38545491/quantitative-measurement-of-hair-diameter-diversity-as-a-diagnostic-indicator-of-androgenetic-alopecia-in-korean-males-a-cross-sectional-study
#1
JOURNAL ARTICLE
Hee Ung Park, Kyung Bae Chung, Do-Young Kim
BACKGROUND: The conventional 20% threshold for hair diameter diversity (HDD), widely accepted for diagnosing androgenetic alopecia (AGA) in the vertex area, has not quantitatively analyzed. OBJECTIVE: To validate the HDD 20% threshold for AGA and develop a refined, Korean-specific criterion. METHODS: This study involved 240 male patients with AGA, categorized by the V stages of the basic and specific classification. Phototrichogram images of the vertex region were analyzed using Image J software for hair thickness measurement...
June 2024: JAAD international
https://read.qxmd.com/read/38542050/a-novel-method-for-determining-fibrin-fibrinogen-degradation-products-and-fibrinogen-threshold-criteria-via-artificial-intelligence-in-massive-hemorrhage-during-delivery-with-hematuria
#2
JOURNAL ARTICLE
Yasunari Miyagi, Katsuhiko Tada, Ichiro Yasuhi, Keisuke Tsumura, Yuka Maegawa, Norifumi Tanaka, Tomoya Mizunoe, Ikuko Emoto, Kazuhisa Maeda, Kosuke Kawakami, On Behalf Of The Collaborative Research In National Hospital Organization Network Pediatric And Perinatal Group
(1) Background: Although the diagnostic criteria for massive hemorrhage with organ dysfunction, such as disseminated intravascular coagulation associated with delivery, have been empirically established based on clinical findings, strict logic has yet to be used to establish numerical criteria. (2) Methods: A dataset of 107 deliveries with >2000 mL of blood loss, among 13,368 deliveries, was obtained from nine national perinatal centers in Japan between 2020 and 2023. Twenty-three patients had fibrinogen levels <170 mg/dL, which is the initiation of coagulation system failure, according to our previous reports...
March 21, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38538448/pharmaceutical-recommendations-for-therapeutic-appropriateness-in-multiple-sclerosis-patients
#3
JOURNAL ARTICLE
María Del Mar Sánchez Suárez, Alicia Martín Roldán, Maria Rosa Cantudo Cuenca, Alberto Jiménez Morales
OBJECTIVE: To determine the prevalence of PIMDINAC criteria and to implement pharmacological interventions in a population with multiple sclerosis over 55 years of age. METHODS: Retrospective observational open-label study including patients with multiple sclerosis aged 55 years and older between December 2022 and February 2023. The main variable determined was the percentage of compliance with the PIMDINAC criteria. RESULTS: Ninety-five patients were included, with the presence of PIMDINAC criteria detected in 67...
March 26, 2024: Farmacia Hospitalaria
https://read.qxmd.com/read/38538229/self-modulation-of-gamma-band-synchronization-through-eeg-neurofeedback-training-in-the-elderly
#4
JOURNAL ARTICLE
Katia Andrade, Nesma Houmani, Thomas Guieysse, Solofo Razafimahatratra, André Klarsfeld, Gérard Dreyfus, Bruno Dubois, François Vialatte, Takfarinas Medani
BACKGROUND: Electroencephalography (EEG) stands as a pivotal non-invasive tool, capturing brain signals with millisecond precision and enabling real-time monitoring of individuals' mental states. Using appropriate biomarkers extracted from these EEG signals and presenting them back in a neurofeedback loop offers a unique avenue for promoting neural compensation mechanisms. This approach empowers individuals to skillfully modulate their brain activity. Recent years have witnessed the identification of neural biomarkers associated with aging, underscoring the potential of neuromodulation to regulate brain activity in the elderly...
March 21, 2024: Journal of Integrative Neuroscience
https://read.qxmd.com/read/38525524/development-and-validation-of-the-gratitude-for-food-scale-for-japanese-adults
#5
JOURNAL ARTICLE
Yui Kawasaki, Sayaka Nagao-Sato, Misa Shimpo, Rie Akamatsu, Yoko Fujiwara
Gratitude for food is a concept associated with various aspects of healthy and sustainable diet and originates from Buddhism and Shintoism in Japan. Against this background, a scale specifically targeting adults is essential for boosting studies concerning gratitude for food. This study aimed to adapt the Gratitude for Food Scale (GFS), originally developed for Japanese children, to Japanese adults and to examine the reliability and validity of GFS for adults (GFS-A). This cross-sectional study used baseline and one-week follow-up data from a longitudinal survey...
March 25, 2024: Global Health Promotion
https://read.qxmd.com/read/38521440/valvulitis-a-new-echocardiographic-criterion-for-the-diagnosis-of-bioprosthetic-aortic-valve-infective-endocarditis
#6
JOURNAL ARTICLE
Pablo Zulet, Isidre Vilacosta, Eduardo Pozo, Daniel García Arribas, Carlos Nicolás Pérez-García, Manuel Carnero, Daniel Pérez Camargo, Lourdes Montero, Melchor Saiz Pardo, Patricia Mahía, Adrián Jerónimo, Fabián Islas, Daniel Gómez, José Alberto San Román, José Alberto De Agustín, Carmen Olmos
INTRODUCTION AND OBJECTIVES: Diffuse homogeneous hypoechoic leaflet thickening, with a wavy leaflet motion documented by transesophageal echocardiography (TEE), has been described in some cases of prosthetic valve endocarditis (PVE) involving aortic bioprosthesis (AoBio-PVE). This echocardiographic finding has been termed valvulitis. We aimed to estimate the prevalence of valvulitis, precisely describe its echocardiographic characteristics, and determine their clinical significance in patients with AoBio-PVE...
March 21, 2024: Revista Española de Cardiología
https://read.qxmd.com/read/38505992/oral-hygiene-in-critically-ill-patients-at-a-tertiary-hospital-in-s%C3%A3-o-paulo-brazil-a-best-practice-implementation-project
#7
JOURNAL ARTICLE
Mariana Davies Ribeiro Bersaneti, Renata Desordi Lobo, Thais Bianca Brandão, Regina Claudia Silva Souza, Vanessa de Brito Poveda
OBJECTIVES: This project aimed to promote evidence-based practices relat. ed to the oral health of critically ill patients in an intensive care unit in Brazil. INTRODUCTION: The oral hygiene of patients on mechanical ventilation is an essential component of nursing care quality, and well-defined guidelines ensure appropriate care. Mechanical ventilation is associated with the risk of ventilator-associated pneumonia, which can increase mortality, length of stay, time on mechanical ventilation, and hospital costs...
March 21, 2024: JBI evidence implementation
https://read.qxmd.com/read/38498662/a-validity-study-of-comlex-usa-level-3-with-the-new-test-design
#8
JOURNAL ARTICLE
Xia Mao, John R Boulet, Jeanne M Sandella, Michael F Oliverio, Larissa Smith
CONTEXT: The National Board of Osteopathic Medical Examiners (NBOME) administers the Comprehensive Osteopathic Medical Licensing Examination of the United States (COMLEX-USA), a three-level examination designed for licensure for the practice of osteopathic medicine. The examination design for COMLEX-USA Level 3 (L3) was changed in September 2018 to a two-day computer-based examination with two components: a multiple-choice question (MCQ) component with single best answer and a clinical decision-making (CDM) case component with extended multiple-choice (EMC) and short answer (SA) questions...
March 19, 2024: Journal of osteopathic medicine
https://read.qxmd.com/read/38497925/the-quest-for-down-scale-representativeness-how-to-exploit-cfd-to-design-a-shear-study-for-vaccines
#9
JOURNAL ARTICLE
Andrea Albano, Silvio Colomba, Angelo Palmese, Jessica Salvadori, Lorenzo Mencuccini, Alessio Moriconi, Federica Bellato, Carmine Malzone, Stefania Berti, Marilena Paludi, Caterina Valoti, Giuseppe Panariello, Nicola Cozzolino, Carlo Pergola
In this work we exploit Computational Fluid Dynamics (CFD) to evaluate Stirred Tank Reactor (STR) Process Engineer Parameters (PEP) and design a scale down system (SDS) to be representative of the formulation and filling process steps for an Aluminum adjuvanted vaccine Drug Product (DP). To study the shear history in the SDS we used the concept of number of passages, combined with an appropriate stirring speed down scale strategy comprising of either i) Tip speed equivalence, widely used as scale-up criterion for shear-sensitive product, or ii) Rotating shear, a shear metric introduced by Metz and Otto in 1957 but never used as scaling criterion...
March 18, 2024: Pharmaceutical Development and Technology
https://read.qxmd.com/read/38493770/place-of-concordance-discordance-model-in-evaluating-ngs-performance
#10
Yue Zhai, Claire Bardel, Maxime Vallée, Jean Iwaz, Pascal Roy
INTRODUCTION: Ideally, evaluating NGS performance requires a gold standard; in its absence, concordance between replicates is often used as substitute standard. However, the appropriateness of the concordance-discordance criterion has been rarely evaluated. This study analyzes the relationship between the probability of discordance and the probability of error under different conditions. METHODS: This study used a conditional probability approach under conditional dependence then conditional independence between two sequencing results and compares the probabilities of discordance and error in different theoretical conditions of sensitivity, specificity, and correlation between replicates, then on real results of sequencing genome NA12878...
March 16, 2024: Human Heredity
https://read.qxmd.com/read/38492443/psychometric-properties-and-factor-structure-of-the-suicidal-narrative-inventory-in-major-depression-a-multicentric-evaluation
#11
JOURNAL ARTICLE
Vikas Menon, Ilambaridhi Balasubramanian, Megan L Rogers, Sandeep Grover, Bhavesh Lakdawala, Rajeev Ranjan, Sujit Sarkhel, Naresh Nebhinani, Roy Abraham Kallivayalil, Vijaya Raghavan, Kshirod Kumar Mishra, Jitender Aneja, Niteen Abhivant, Raman Deep, Lokesh Kumar Singh, Avinash De Sousa, Arvind Nongpiur, Alka A Subramanyam, Debadatta Mohapatra, Sujita Kumar Kar, Vishal Dhiman, Pn Suresh Kumar, Umesh Shreekantiah, Samrat Singh Bhandari, Ramdas Ransing, Vikhram Ramasubramanian, Samir Kumar Praharaj
BACKGROUND: The Suicidal Narrative Inventory (SNI) is a 38-item self-report measure developed to assess elements of the suicidal narrative, a subacute, predominantly cognitive, presuicidal construct. Our objectives were to assess the factor structure, validity, and reliability of the SNI-38 among adults with major depressive disorder (MDD). METHODS: Using a cross-sectional design, we administered the Hindi version of the SNI along with other self-report measures to adults with MDD, recruited from 24 tertiary care hospitals across India...
March 8, 2024: Asian Journal of Psychiatry
https://read.qxmd.com/read/38487576/utility-of-the-3di-short-version-in-the-identification-and-diagnosis-of-autism-in-children-at-the-kenyan-coast
#12
JOURNAL ARTICLE
Patricia Kipkemoi, Symon M Kariuki, Joseph Gona, Felicita Wangeci Mwangi, Martha Kombe, Collins Kipkoech, Paul Murimi, William Mandy, Richard Warrington, David Skuse, Charles R J C Newton, Amina Abubakar
INTRODUCTION: The precise epidemiological burden of autism is unknown because of the limited capacity to identify and diagnose the disorder in resource-constrained settings, related in part to a lack of appropriate standardised assessment tools and health care experts. We assessed the reliability, validity, and diagnostic accuracy of the Developmental Diagnostic Dimensional Interview (3Di) in a rural setting on the Kenyan coast. METHODS: Using a large community survey of neurodevelopmental disorders (NDDs), we administered the 3Di to 2,110 children aged between 6 years and 9 years who screened positive or negative for any NDD and selected 242 who had specific symptoms suggestive of autism based on parental report and the screening tools for review by a child and adolescent psychiatrist...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38465420/selection-of-radionuclide-s-for-targeted-alpha-therapy-based-on-their-nuclear-decay-properties
#13
JOURNAL ARTICLE
Samantha M Ree, Howard Greenwood, Jennifer D Young, Rachel F C Roberts, Francis R Livens, Scott L Heath, Jane K Sosabowski
Targeted alpha therapy (TAT) is a promising form of oncology treatment utilising alpha-emitting radionuclides that can specifically accumulate at disease sites. The high energy and high linear energy transfer associated with alpha emissions causes localised damage at target sites whilst minimising that to surrounding healthy tissue. The lack of appropriate radionuclides has inhibited research in TAT. The identification of appropriate radionuclides should be primarily a function of the radionuclide's nuclear decay properties, and not their biochemistry or economic factors since these last two factors can change; however, the nuclear decay properties are fixed to that nuclide...
March 11, 2024: Nuclear Medicine Communications
https://read.qxmd.com/read/38463145/alcohol-relapse-after-early-liver-transplantation-in-patients-with-alcoholic-liver-disease-a-meta-analysis
#14
JOURNAL ARTICLE
Yousaf Zafar, Ahmed Kamal Siddiqi, Nafhat Shaikh, Maria Imran, Syed Sarmad Javaid, Laila Manzoor, Arsalan Zafar Iqbal, Jan Petrasek
BACKGROUND: Alcohol use disorder (AUD) is a significant source of end-stage liver disease and liver failure and an indication for liver transplant (LT). Historically, LT for alcoholic liver disease (ALD) required 6 months of alcohol abstinence. Recently, it has been demonstrated that early LT (< 6 months of abstinence) in strictly selected group of patients provides survival benefit while keeping the relapse to harmful drinking at acceptable levels. This practice has been reflected in the Dallas consensus, but more data are needed to appropriately risk stratify the patient from the perspective of return to harmful alcohol drinking post-transplant...
February 2024: Gastroenterology Research
https://read.qxmd.com/read/38458932/cultivating-competency-in-cardiac-sonography-aligning-entrustable-professional-activities-with-industry-expectations
#15
JOURNAL ARTICLE
Rebecca Perry, Anthony Forshaw, Jessie Childs, Deanne Chester, Christopher Edwards
BACKGROUND & AIM: Echocardiography education involves the teaching and assessment of multiple competencies to ensure work-ready graduates. To connect these competency standards to professional practice, it is important that the industry expectation around specific entrustable professional activities (EPAs) is determined. In Australia, echocardiography examinations are eligible for Medicare reimbursement when performed by sonographers listed on the Australian Sonographers Accreditation Registry (ASAR), either as an Accredited Medical Sonographer or as an Accredited Student Sonographer...
March 7, 2024: Heart, Lung & Circulation
https://read.qxmd.com/read/38454334/is-early-bilateral-compression-ultrasonography-and-d-dimer-monitoring-appropriately-for-prophylaxis-and-diagnosis-of-deep-venous-thrombosis-after-cesarean-section-women-a-single-center-observation-study-of-chinese-han-population
#16
JOURNAL ARTICLE
Xiuying Chen, Haiyan Jiang, Aiping Zhou, Quan Zhang, Minmin Du, Yun Sun, Baihui Zhao
BACKGROUND: Venous thromboembolism (VTE) is most prevalent among parturients following a cesarean section (CS). The objective of this study was to assess the practical utility of bilateral compression ultrasonography (CUS) of the lower limbs, coupled with D-dimer monitoring, in the early diagnosis of VTE within the Han Chinese population. METHODS: Our prospective observational study included 742 women who underwent CUS and D-dimer testing on the first day post-CS...
March 7, 2024: BMC Pregnancy and Childbirth
https://read.qxmd.com/read/38443079/selecting-an-e-cigarette-for-use-in-smoking-cessation-interventions-and-healthcare-services-findings-from-patient-and-public-consultation-for-the-costed-trial
#17
JOURNAL ARTICLE
Pippa Belderson, Emma Ward, Ian Pope, Caitlin Notley
OBJECTIVES: The Cessation of Smoking Trial in the Emergency Department (COSTED) trial aims to ascertain whether brief advice, the provision of an e-cigarette starter kit and referral to stop smoking services (SSS), increases smoking cessation in people attending the emergency department. Patient and public involvement (PPI) and scoping work were undertaken to select an appropriate e-cigarette for the trial. DESIGN AND SETTING: PPI consultation and feasibility scoping about potential devices with a professional and lay panel, all based in England...
March 4, 2024: BMJ Open
https://read.qxmd.com/read/38437254/carrier-frequency-estimation-for-digital-holograms-of-phase-objects
#18
JOURNAL ARTICLE
Nishant Goyal, Kedar Khare
Accurate estimation of carrier fringe frequency is essential for the demodulation of off-axis digital holograms. The fringe frequency is often associated with the amplitude peak of the cross-term in the two-dimensional Fourier transform of a digital hologram. We point out that this definition of carrier frequency is not valid in general for holograms associated with phase objects. We examine the carrier-envelope representation for digital holograms from the viewpoint of Mandel's criterion [J. Opt. Soc. Am.57, 613 (1967)10...
March 1, 2024: Applied Optics
https://read.qxmd.com/read/38437222/self-efficacy-measurement-instruments-for-individuals-with-coronary-artery-disease-a-systematic-review
#19
JOURNAL ARTICLE
José Alexandre Barbosa de Almeida, Rêncio Bento Florêncio, Jéssica Costa Leite, Karolinne Souza Monteiro, Lucien Peroni Gualdi
INTRODUCTION: Over the past decade, there has been a heightened interest in evaluating self-efficacy among patients with coronary artery disease (CAD). A significant number of instruments have been developed and validated, yet the need remains to assess the quality of their studies and their properties. OBJECTIVES: To evaluate the measurement properties and link the content extracted from self-efficacy instrument items for individuals with CAD to the International Classification of Functioning, Disability, and Health (ICF)...
2024: PloS One
https://read.qxmd.com/read/38434104/boundary-integrity-testing-of-containment-level-3-biological-safety-level-3-laboratories
#20
JOURNAL ARTICLE
Cory Ziegler, Gilles Tremblay
BACKGROUND: Containment Level 3 (CL3) laboratories may require boundary integrity testing. Existing guidelines for CL3 room leakage are often subjective, lacking a definitive standard for what constitutes a "sealed" room. METHODS: This study reviews global biocontainment guidelines and standards, and it compares multiple test results from global CL3 facilities by standardizing test data to an equivalent test pressure of 250 Pa. RESULTS: Our analysis revealed that 55% of rooms constructed using typical CL3 methodologies met the proposed testing criteria...
March 1, 2024: Applied Biosafety: Journal of the American Biological Safety Association
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