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Pain research

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https://www.readbyqxmd.com/read/28742777/lack-of-association-between-the-use-of-nerve-blockade-and-the-risk-of-persistent-opioid-use-among-patients-undergoing-shoulder-arthroplasty-evidence-from-the-marketscan-database
#1
Kathryn G Mueller, Stavros G Memtsoudis, Edward R Mariano, Laurence C Baker, Sean Mackey, Eric C Sun
BACKGROUND: Persistent opioid use following surgery has received increasing attention from policymakers, researchers, and clinicians. Perioperative nerve blockade has been hypothesized to decrease the risk of persistent opioid use. We examined whether nerve blockade was associated with a decreased risk of persistent opioid use among patients undergoing shoulder arthroplasty, a procedure with high rates of persistent postoperative pain. METHODS: Using health care claims data, we constructed a sample of 6695 patients undergoing shoulder arthroplasty between 2002 and 2012 and used billing data to identify the utilization of nerve blockade...
July 21, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28742609/the-efficacy-of-dynamic-contract-relax-stretching-on-delayed-onset-muscle-soreness-among-healthy-individuals-a-randomized-clinical-trial
#2
Yanfei Xie, Beibei Feng, Kedi Chen, Lars L Andersen, Phil Page, Yuling Wang
OBJECTIVE: To evaluate the efficacy of dynamic contract-relax stretching on delayed-onset muscle soreness (DOMS) in the calf muscle of healthy individuals. DESIGN: Randomized clinical trial. SETTING: Research laboratory. PARTICIPANTS: Three groups of 16 healthy participants (n = 48) were recruited by convenience sampling. INTERVENTIONS: Three sets of resisted bilateral heel-raising exercises until exhaustion were conducted to initiate DOMS...
July 21, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/28742289/tai-chi-exercise-for-the-quality-of-life-in-a-perimenopausal-women-organization-a-systematic-review
#3
Ying Wang, Weichao Shan, Qing Li, Na Yang, Weiying Shan
BACKGROUND: Improvement of the quality of life in perimenopausal women has recently become an important global health issue. Extensive research reports provide evidence of Tai Chi for the quality of life, but no systematic review has individually investigated Tai Chi as a main intervention on the quality of life in perimenopausal women. OBJECTIVE: To assess clinical evidence of Tai Chi for the quality of life in perimenopausal women. METHODS: Studies related to the effect of Tai Chi on the quality of life in perimenopausal women in the databases of China and abroad were searched...
August 2017: Worldviews on Evidence-based Nursing
https://www.readbyqxmd.com/read/28742263/progesterone-receptor-modulators-for-endometriosis
#4
REVIEW
Jing Fu, Hao Song, Min Zhou, Huili Zhu, Yuhe Wang, Hengxi Chen, Wei Huang
BACKGROUND: Endometriosis is defined as the presence of endometrial tissue (glands and stroma) outside the uterine cavity. This condition is oestrogen-dependent and thus is seen primarily during the reproductive years. Owing to their antiproliferative effects in the endometrium, progesterone receptor modulators (PRMs) have been advocated for treatment of endometriosis. OBJECTIVES: To assess the effectiveness and safety of PRMs primarily in terms of pain relief as compared with other treatments or placebo or no treatment in women of reproductive age with endometriosis...
July 25, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28742210/clinical-research-on-correction-of-ankle-arthritis-related-factor-levels-via-urea
#5
C Sun, S Zhang, L Wei, J-Z Zhang
OBJECTIVE: To investigate the reliability of urea as the internal reference of ankle irrigating fluid in correction of synovial fluid and related factor concentration dilution times, and to further determine the factor expression level in synovial fluid. PATIENTS AND METHODS: A total of 91 patients, including 20 cases of non-posterior median foot lesions and 71 cases of unilateral ankle osteoarthritis, were enrolled in this study. AOFAS score, Takakura staging and visual analogue pain scale were given; the venous blood was collected and the ankle fluid and irrigating fluid were obtained from the affected side via puncture...
July 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28741410/how-can-precision-medicine-be-applied-to-temporomandibular-disorders-and-its-comorbidities
#6
Joan B Wilentz, Allen W Cowley
The Eighth Scientific Meeting of The TMJ Association, Ltd. was held in Bethesda, Maryland, September 11-13, 2016. As in the past, the meeting was cosponsored by components of the National Institutes of Health with speakers invited to review the state of temporomandibular disorder science and propose recommendations to further progress. The theme of precision medicine, which aims to tailor disease treatment and prevention to match the characteristics of an individual patient (genetic, epigenetic, environmental, lifestyle) underscored the current consensus that temporomandibular disorders are no longer viewed as local conditions of jaw pain and dysfunction...
January 2017: Molecular Pain
https://www.readbyqxmd.com/read/28741278/italian-intersociety-consensus-on-prevention-diagnosis-and-treatment-of-delirium-in-hospitalized-older-persons
#7
Giuseppe Bellelli, Alessandro Morandi, Marco Trabucchi, Guido Caironi, Daniele Coen, Carlo Fraticelli, Ciro Paolillo, Carolina Prevaldi, Angela Riccardi, Gianfranco Cervellin, Corrado Carabellese, Salvatore Putignano, Stefania Maggi, Antonio Cherubini, Paola Gnerre, Andrea Fontanella, Nicola Latronico, Concezione Tommasino, Antonio Corcione, Giovanni Ricevuti, Nicola Ferrara, Francesco De Filippi, Alberto Ferrari, Mario Guarino, Maria Pia Ruggieri, Pietro Amedeo Modesti, Carlo Locatelli, Patrizia Hrelia, Marco Otto Toscano, Emi Bondi, Antonio Tarasconi, Luca Ansaloni, Francesco Perticone
Delirium is a severe neuropsychiatric syndrome characterized by inattention and global cognitive dysfunction in the setting of an acute medical illness, medical complication, drug intoxication, or drug withdrawal. The most important risk factors are advanced age and dementia, whereas pain, dehydration, infections, stroke, metabolic disturbances, and surgery are the most common triggering factors. Although delirium is a common clinical syndrome in different settings of care (acute care hospitals, inpatient rehabilitation facilities, nursing homes, and hospices), it often remains under-recognized, poorly understood, and inadequately managed...
July 24, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28740997/guidelines-for-bystander-first-aid-2016
#8
Jen Heng Pek
Cardiac life support is a form of first aid for cardiac emergencies. However, research and evidence in this field is lacking compared with other forms of first aid. Having identified the common emergencies that are encountered in the hospital, based on the available evidence, we have put together what could be an evidence-based approach to the first aid management of some of these common emergencies, viz. breathlessness, chest pain, allergies, stroke, heat injury, poisoning, unconsciousness, seizures, and trauma situations such as bleeding, wounds, contusions, head injury, burns and fractures...
July 2017: Singapore Medical Journal
https://www.readbyqxmd.com/read/28740424/risk-and-protective-factors-in-the-clinical-rehabilitation-of-chronic-back-pain
#9
Pia-Maria Wippert, Michael Fliesser, Matthias Krause
OBJECTIVES: Chronic back pain (CBP) can lead to disability and burden. In addition to its medical causes, its development is influenced by psychosocial risk factors, the so-called flag factors, which are categorized and integrated into many treatment guidelines. Currently, most studies investigate single flag factors, which limit the estimation of individual factor significance in the development of chronic pain. Furthermore, factors concerning patients' lifestyle, biography and treatment history are often neglected...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28740420/a-cross-cultural-perspective-of-medical-clowning-comparison-of-its-effectiveness-in-reducing-pain-and-anxiety-among-hospitalized-bedouin-and-jewish-israeli-children
#10
Zehavit Gilboa-Negari, Sarah Abu-Kaf, Ephrat Huss, Gavriel Hain, Asher Moser
PURPOSE: Medical clowning has proven effective for reducing pain, anxiety, and stress, however, its differential effects on children from different cultures have not yet been researched. This study evaluated the effects of medical-clowning intervention on anxiety and pain among Jewish and Bedouin children, and anxiety among their parents, in southern Israel. PATIENTS AND METHODS: The study was conducted in hospital pediatric departments and employed a pre-post design involving quantitative and qualitative methods...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28738963/-somatization-symptoms-in-lung-cancer-patients-and-correlative-analysis-between-anxiety-depression-and-somatization-symptoms
#11
Xinyao Zhang, Xiaoye Zhang
BACKGROUND: Lung cancer is a serious threat to human health and its morbidity and mortality in recent years has always been ranked first in the country. Lung cancer patients are often associated with anxiety, depression and other emotional problems, and anxiety, depression and other emotional problems will further lead to a series of somatic symptoms. At present, we lack the clinical understanding of somatization symptoms in patients with lung cancer and related clinical studies are not too much...
July 20, 2017: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
https://www.readbyqxmd.com/read/28738936/favorable-outcomes-in-blunt-chest-injury-with-noninvasive-bi-level-positive-airway-pressure-ventilation
#12
Pascal Udekwu, Sahill Patel, Meagan Farrell, Rhonda Vincent
Recent clinical research in patients with blunt chest injury has focused on the benefits of surgical fixation of rib fractures. Noninvasive ventilation (NIV) has been demonstrated to prevent the need for intubation and ventilation in posttraumatic respiratory failure. The preemptive use of NIV in patients with rib fractures has not been extensively studied. Our study evaluated the outcomes of patients with ≥3 rib fractures and hospitalized for ≥ 4 days. Seventy-one patients treated with NIV were compared with 270 patients without NIV...
July 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28738744/pain-profiles-in-a-community-dwelling-population-following-spinal-cord-injury-a-national-survey
#13
Dearbhla Burke, Brona M Fullen, Olive Lennon
CONTEXT: While as many as 60% of patients with spinal cord injury (SCI) develop chronic pain, limited data currently exists on the prevalence and profile of pain post-SCI in community dwelling populations. STUDY DESIGN: A cross-sectional population survey. SETTING: Primary care. PARTICIPANTS: Community dwelling adults with SCI. METHODS: Following ethical approval members registered to a national SCI database (n=1,574) were surveyed...
July 24, 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/28738737/20-20-hindsight-a-25-year-programme-at-the-anna-freud-centre-of-efficacy-and-effectiveness-research-on-child-psychoanalytic-psychotherapy
#14
Mary Target
OBJECTIVE: This paper describes the evolution of methods of enquiry-through 25 years of work, with Professor Peter Fonagy and many other colleagues-of research and theorizing about child and adolescent therapy outcomes. METHOD: The work has focused on measuring psychoanalytic outcomes, but with an increasing interest in discovering therapeutic elements across treatment modalities. RESULTS: Headline findings are described, with lessons from the ups and downs of developing (a) retrospective, follow-up, and prospective outcome studies, and (b) measures of child and family functioning...
July 24, 2017: Psychotherapy Research: Journal of the Society for Psychotherapy Research
https://www.readbyqxmd.com/read/28738165/physical-and-mechanical-therapies-for-lower-limb-problems-in-juvenile-idiopathic-arthritis-a-systematic-review-with-meta-analysis
#15
Antoni Fellas, Andrea Coda, Fiona Hawke
BACKGROUND: Juvenile Idiopathic Arthritis (JIA) is a chronic, autoimmune, inflammatory joint disease and is the most common arthritis affecting children under 16 years of age. Children with JIA commonly experience lower limb dysfunction and disability. OBJECTIVE: To systematically review the effectiveness of physical and mechanical therapies for lower limb problems JIA. METHODS: Randomised control trials (RCT) of physical and mechanical interventions for lower limb problems in children with JIA were included...
July 24, 2017: Journal of the American Podiatric Medical Association
https://www.readbyqxmd.com/read/28738107/acupuncture-in-temporomandibular-disorder-myofascial-pain-treatment-a-systematic-review
#16
Ana Carla Fernandes, Dayanne Monielle Duarte Moura, Laura Géssica Dantas Da Silva, Erika Oliveira De Almeida, Gustavo Augusto Seabra Barbosa
AIMS: To carry out a systematic review of clinical trials published up to 2015 to determine the effectiveness of acupuncture in treating myofascial pain in temporomandibular disorder (TMD) patients. METHODS: The databases used were the Cochrane Library, PubMed, Scopus, and Web of Science; the dates of the articles surveyed ranged from 1990 to May 2015. The inclusion criteria were: (1) publications in English, Portuguese, or Spanish; (2) controlled clinical trials; (3) patients with TMD of muscular origin; and (4) studies that used acupuncture or laser acupuncture only for treatment...
July 2017: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/28738106/predictors-of-clinically-significant-outcome-for-adolescents-with-temporomandibular-disorders
#17
Kerstin Wahlund, Bo Larsson
AIMS: To evaluate and identify baseline characteristics of the adolescent patients included in two previous randomized controlled trials (RCTs) that may predict a clinically significant outcome after treatment of temporomandibular disorders (TMD) with an occlusal appliance (OA) or relaxation training (RT) in a clinical sample of adolescents. METHODS: This study combined two patient samples from the earlier RCTs for a total of 167 adolescents with frequent TMD pain (once a week or more often), diagnosed according to the Research Diagnostic Criteria for TMD...
July 2017: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/28738104/psychosocial-profiles-of-temporomandibular-disorder-pain-patients-proposal-of-a-new-approach-to-present-complex-data
#18
Simple Futarmal Kothari, Lene Baad-Hansen, Peter Svensson
AIMS: To propose a visual method to screen and assess psychosocial functioning in temporomandibular disorder (TMD) pain patients in comparison with age- and gender-matched healthy controls by forming individual profiles and to evaluate the association between psychosocial profiles and quantitative sensory testing (QST) findings of TMD pain patients. METHODS: TMD patients (n = 58) and control participants (n = 41) completed a set of questionnaires profiling their psychosocial function, and QST was performed at the temporomandibular joint (TMJ) on both sides of the face in all participants...
July 2017: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/28737670/motor-control-training-for-the-shoulder-with-smart-garments
#19
Qi Wang, Liesbet De Baets, Annick Timmermans, Wei Chen, Luca Giacolini, Thomas Matheve, Panos Markopoulos
Wearable technologies for posture monitoring and posture correction are emerging as a way to support and enhance physical therapy treatment, e.g., for motor control training in neurological disorders or for treating musculoskeletal disorders, such as shoulder, neck, or lower back pain. Among the various technological options for posture monitoring, wearable systems offer potential advantages regarding mobility, use in different contexts and sustained tracking in daily life. We describe the design of a smart garment named Zishi to monitor compensatory movements and evaluate its applicability for shoulder motor control training in a clinical setting...
July 22, 2017: Sensors
https://www.readbyqxmd.com/read/28736816/antinociceptive-activity-of-ent-dihydrotucumanoic-acid-isolated-from-gymnosperma-glutinosum-spreng-less
#20
Angel Josabad Alonso-Castro, Marco Martin González-Chávez, Juan Ramón Zapata-Morales, Alexia Karina Verdinez-Portales, Amanda Sánchez-Recillas, Rolffy Ortiz-Andrade, Mario Isiordia-Espinoza, Fidel Martínez-Gutiérrez, Marco Antonio Ramírez-Morales, Fabiola Domínguez, María Elizabeth Juache-Flores, Roberto Martínez
Preclinical Research The diterpene ent-dihydrotumanoic acid (DTA) was among the compounds isolated from Gymnosperma glutinosum (Spreng) Less (Asteraceae). There are no reports regarding the pharmacological effects of DTA. Cytotoxicity against cancer cells (1-250 µM), and the antibacterial (50-1400 µM) activity of DTA were evaluated using the MTT assay, and the minimum inhibitory concentration test, respectively. The antidiarrheal (1-100 mg/kg p.o.) and anti-inflammatory (2 mg/ear) effects of DTA were evaluated using castor oil and 12-O-tetradecanoylphorbol-13-acetate, respectively...
July 24, 2017: Drug Development Research
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