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JOURNAL ARTICLE
Pablo Mesa-Del-Castillo, Inés Yago Ugarte, J M Bolarín, David Martínez, Berta López Montesinos, Honorio Barranco González, Inmaculada Calvo Penadés, Lucia Lacruz Pérez, Daniel Clemente, Juan Carlos Robledillo, Isabel Valls Ferrán, Beatriz Bravo Mancheño, Marina Rubio Plats, Laura Martín Pedraz, Carmen Alba Linero, Belén Sevilla-Pérez, J L García-Serrano, Maria Concepcion Mir-Perelló, Noelia Druetta, Alex Souto, Fernando Lopez-Lopez, Cristina Zarallo-Reales, María Jerez Fidalgo, Jorge Solana Fajardo, Natalia Palmou Fontana, Rosalia Demetrio Pablo, Mari Carmen Pinedo, Alex Fonollosa, Vega Jovani Casano, Jose Juan Mondejar García, Anahy Brandy, Alba García López, M Esteban-Ortega, Teresa Reinoso, Joan Calzada-Hernández, Ana Llorca Cardeñosa, César Gavilán Martín, Encarna Mengual Verdú, Mari Paz Martínez Vidal, Neus Quilis Martí, M C Alvarado, Jaime De Inocencio, Beatriz Alonso-Martín, Sheila Recuero-Diaz, Ester Carreño, Juan Carlos Nieto González, Lucia Ibares, Jose Rosas Gómez de Salazar, Juan Luis Sánchez Sevila
OBJECTIVE: To characterize and describe clinical experience with childhood-onset non-infectious uveitis. STUDY DESIGN: A multicenter retrospective multidisciplinary national web-based registry of 507 patients from 21 hospitals was analyzed. Cases were grouped as immune disease-associated (IMDu), idiopathic (IDIu) or ophthalmologically distinct. Characteristics of juvenile idiopathic arthritis-associated (non-HLA-B27-related) uveitis (JIAu), IDIu, and pars planitis (PP) were compared...
May 10, 2024: Ocular Immunology and Inflammation
#2
JOURNAL ARTICLE
Jenny Carolina Rodríguez-Villalobos, Christian Cortés Fuentes, Héctor Reyes-Bonilla, Arturo Ayala-Bocos, Imelda G Amador-Castro, Irma González López, M Sylviane Jaume-Schinkel, Elia López Greene, Adrian Munguia-Vega, Ollin T Gonzalez-Cuellar
This dataset comes from a multi-institution compilation of monitoring information for 13 marine herbivorous fishes belonging to six genera of five families: Acanthuridae, Girellidae, Kyphosidae, Pomacentridae and Scaridae, gathered from 2005 to 2020 in the Gulf of California. The database presents a total of 884 records of biomass and density got from 15,542 visual censuses performed using scuba diving in 34 localities comprising 268 rocky and coral reef sites. The censuses consisted of belt transects (250 m2 , 100 m2 , and 60 m2 ) laid parallel to the coastline, where expert monitors recorded the abundance of all observed adult individuals of the 13 target herbivorous species, and visually estimated the total length (cm) of each fish...
June 2024: Data in Brief
#3
JOURNAL ARTICLE
Mely Olarte-Durand, Jossiel B Roque-Aycachi, Ricardo Rojas-Humpire, Josue F Canaza-Apaza, Stefani Laureano, Andrea Rojas-Humpire, Salomón Huancahuire-Vega
INTRODUCTION: The prolongation and consequences of the COVID-19 pandemic have led to an uncertain and devastating panorama in many populations, and the evidence shows a high prevalence of mental health problems in medical students. The objective was to evaluate the association between mood disorders and sleep quality (SQ) in Peruvian medical students during the COVID-19 pandemic. METHODS: A cross-sectional study was conducted on 310 medical students from a private university in Peru...
2024: Revista Colombiana de psiquiatría (English ed.)
#4
JOURNAL ARTICLE
Federico Vega
Robert Rosen defines organisms as material systems closed to efficient causation, and proposes the replicative (M, R) system as a model for them. Vega (2023) proposes a cell model that realizes Rosen's formal model, based on Hofmeyr's (2017) analysis of the functional organization of cell biochemistry and on Rosen's construction of the replication function. In this article we propose a cell model that, starting from the same biochemical processes, replaces the replication function with a set of semiotic relations between some of the elements that participate in cellular processes...
May 7, 2024: Bio Systems
#5
RANDOMIZED CONTROLLED TRIAL
Vincent Costalat, Tudor G Jovin, J F Albucher, Christophe Cognard, Hilde Henon, Nasreddine Nouri, Benjamin Gory, Sebastien Richard, Gaultier Marnat, Igor Sibon, Federico Di Maria, Mariam Annan, Grégoire Boulouis, Pere Cardona, Michael Obadia, Michel Piotin, Romain Bourcier, Benoit Guillon, Sophie Godard, Anne Pasco-Papon, Omer F Eker, Tae-Hee Cho, Guillaume Turc, Olivier Naggara, Stéphane Velasco, Matthias Lamy, Frédéric Clarençon, Sonia Alamowitch, Arturo Renu, Laurent Suissa, Hervé Brunel, Jean-Christophe Gentric, Serge Timsit, Chantal Lamy, Cyril Chivot, Francisco Macian-Montoro, Charbel Mounayer, Ozlem Ozkul-Wermester, Chrysanthi Papagiannaki, Valérie Wolff, Raoul Pop, Anna Ferrier, Emmanuel Chabert, Frédéric Ricolfi, Yannick Béjot, Elena Lopez-Cancio, Pedro Vega, Laurent Spelle, Christian Denier, Mònica Millán, Juan F Arenillas, Mikael Mazighi, Emmanuel Houdart, Maria Del Mar Freijo, Alain Duhamel, Nerses Sanossian, David S Liebeskind, Julien Labreuche, Bertrand Lapergue, Caroline Arquizan
BACKGROUND: The use of thrombectomy in patients with acute stroke and a large infarct of unrestricted size has not been well studied. METHODS: We assigned, in a 1:1 ratio, patients with proximal cerebral vessel occlusion in the anterior circulation and a large infarct (as defined by an Alberta Stroke Program Early Computed Tomographic Score of ≤5; values range from 0 to 10) detected on magnetic resonance imaging or computed tomography within 6.5 hours after symptom onset to undergo endovascular thrombectomy and receive medical care (thrombectomy group) or to receive medical care alone (control group)...
May 9, 2024: New England Journal of Medicine
#6
JOURNAL ARTICLE
O Marcuzzi, F Calcaterra, A Loza Vega, M F Ortega Masagué, E Armstrong, J A Pereira Rico, E Jara, L H Olivera, P Peral García, G Giovambattista
The conservation of animal genetic resources refers to measures taken to prevent the loss of genetic diversity in livestock populations, including the protection of breeds from extinction. Creole cattle populations have suffered a drastic reduction in recent decades owing to absorbent crosses or replacement with commercial breeds of European or Indian origin. Genetic characterization can serve as a source of information for conservation strategies to maintain genetic variation. The objective of this work was to evaluate the levels of inbreeding and kinship through the use of genomic information...
May 8, 2024: Animal Genetics
#7
Deus S Ishengoma, Roly Gosling, Rosario Martinez-Vega, Khalid B Beshir, Jeffrey A Bailey, John Chimumbwa, Colin Sutherland, Melissa D Conrad, Fitsum G Tadesse, Jonathan J Juliano, Moses R Kamya, Wilfred F Mbacham, Didier Ménard, Philip J Rosenthal, Jaishree Raman, Allison Tatarsky, Sofonias K Tessema, David A Fidock, Abdoulaye A Djimde
No abstract text is available yet for this article.
April 25, 2024: Nature Medicine
#8
JOURNAL ARTICLE
Luis Vega, Daniela Simian, Abraham I Gajardo, Marcelo Salinas, Andrea Urra, Máximo Cattaneo, Rosario Pino, Juan P Roblero, Álvaro Urzúa, Katherine Rojas, Jaime Poniachik
INTRODUCTION AND OBJECTIVES: Patients with metabolic dysfunction-associated steatotic liver disease (MASLD) are at an increased cardiovascular risk. On the contrary, non-alcoholic fatty liver disease (NAFLD) is highly prevalent in patients with coronary heart disease (CHD). However, it is not known whether patients with significant CHD show a higher frequency of liver fibrosis. This study aimed to determine the frequency of MASLD and liver fibrosis in patients with CHD and to assess whether coronary stenosis is significantly associated with MASLD and fibrosis...
May 4, 2024: Annals of Hepatology
#9
JOURNAL ARTICLE
Cristina Suárez Ferrer, Francisco Mesonero Gismero, Berta Caballol, Maria Pilar Ballester, Iria Bastón Rey, Andrés Castaño García, Jose Miranda Bautista, Rosa Saiz Chumillas, Jose Manuel Benitez, Laura Sanchez Delgado, Alicia López García, Cristina Rubin de Celix, Inmaculada Alonso Abreu, Luigi Melcarne, Rocío Plaza Santos, Miquel Marques Camí, Antonio Caballero Mateos, César Gómez Díez, Margalida Calafat, Horacio Alonso Galan, Pablo Vega Vilaamil, Beatriz Castro Senosiain, Andrea Guerro Moya, Carmen Yolanda Rodriguez Diaz, Katerina Spicakova, Noemi Manceñdo Marcos, Gema Molina, Luisa de Castro Parga, Andres Rodriguez Angulo, Lidia Cuevas Del Campo, Maria Del Carmen Rodriguez Grau, Fernando Ramirez, Barbara Gomez Pastrana, Irene Gonzalez Partida, Belen Botella Mateu, Elena Peña Gonzalez, Eduardo Iyo, Alfonso Elosua Gonzalez, Empar Sainz Arnau, Luis Hernandez Villalba, Pablo Perez Galindo, Leyanira Torrealba Medina, Sara Monsalve Alonso, Jose Antonio Olmos Perez, Carmen Dueñas Sadornil, Laura Garcia Ramirez, María Dolores Martín-Arranz, Antonio López Sanroman, Agnès Fernández, Victor Merino Murgui, Cristina Calviño Suárez, Pablo Florez, María Elena Lobato Matilla, Beatriz Sicilia, Pilar Soto Escribano, Carlos Maroto Martin, Míriam Mañosa, Manuel Barreiro De Acosta
INTRODUCTION: Biological therapies used for the treatment of inflammatory bowel disease (IBD) have shown to be effective and safe, although these results were obtained from studies involving mostly a young population, who are generally included in clinical trials. The aim of our study was to determine the efficacy and safety of the different biological treatments in the elderly population. METHODS: Multicenter study was carried out in the GETECCU group.Patients diagnosed with IBD and aged over 65 years at the time of initiating biological therapy (infliximab, adalimumab, golimumab, ustekinumab or vedolizumab) were retrospectively included...
May 4, 2024: Gastroenterología y Hepatología
#10
JOURNAL ARTICLE
J Cortes-Ramirez, J D Wilches-Vega, B Caicedo-Velasquez, O M Paris-Pineda, P D Sly
INTRODUCTION: The pandemic had a profound impact on the provision of health services in Cúcuta, Colombia where the neighbourhood-level risk of Covid-19 has not been investigated. Identifying the sociodemographic and environmental risk factors of Covid-19 in large cities is key to better estimate its morbidity risk and support health strategies targeting specific suburban areas. This study aims to identify the risk factors associated with the risk of Covid-19 in Cúcuta considering inter -spatial and temporal variations of the disease in the city's neighbourhoods between 2020 and 2022...
May 15, 2024: Heliyon
#11
JOURNAL ARTICLE
Salyoc Tapia-Rojas, Marlon García-Paitán, Jorge Del Rosario-Chavarri, Alexei Santiani, Santiago Alvarez-Vega, José Amiel-Pérez, Ana Mayanga-Herrera
Fluorescence is used in various biological assays due to its high sensitivity, versatility, and precision. In recent years, studies using medicinal plant extracts have increased. However, fluorescence-based assays could be biased by plant metabolites autofluorescence. To address this issue, this study investigated the interference caused by methanolic extracts and chloroform fractions of three medicinal plants in three fluorescence-based assays on gastric cancer stem cells(CSC): resazurin reduction, confocal microscopy, and flow cytometry...
June 2024: Saudi Journal of Biological Sciences
#12
JOURNAL ARTICLE
Veronica Vega-Cabello, Maymona Al Hiani, Humberto Yévenes-Briones, Francisco Felix Caballero, Esther Lopez-García, Ana Baylin
BACKGROUND: Plant-based diets have gained attention due to their beneficial effects against major chronic diseases, though its association with multimorbidity is mostly unknow. OBJECTIVE: We examined the association between the healthful (hPDI) and unhealthful plant-based diet indices (uPDI) with multimorbidity among middle-aged and older adults from the U.S. METHODS: Data on 4,262 adults over 50 years was drawn from the 2012-2020 Health and Retirement Study (HRS) and 2013 Health Care and Nutrition Study (HCNS)...
May 3, 2024: Journal of Nutrition
#13
JOURNAL ARTICLE
Diogo Moniz-Garcia, Krishnan Ravindran, Aaron Wessell, Mohamed S Muneer, Eglal Ahmed, Carlos Perez Vega, Samir Kashyap, Prasanna Vibhute, Vivek Gupta, William D Freeman, Sukwhinder Sandhu, Rabih Tawk
INTRODUCTION: The prevalence of intracranial aneurysms (IA) in patients with acute ischemic stroke (AIS) requiring mechanical thrombectomy (MT) is unclear. OBJECTIVE: To describe the prevalence of IA in patients with AIS and their influence on MT. MATERIALS & METHODS: This is a retrospective cohort study on all patients admitted with a diagnosis of AIS from January 2008 to March 2022 at a tertiary academic center. The records were reviewed for demographic, clinical, imaging, and outcomes data...
May 1, 2024: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
#14
JOURNAL ARTICLE
Yaumel C Arias-Sosa, Gelaysi Moreno-Vega, Rubens M Lopes, José-Luis Valin-Rivera, Meylí Valin-Fernández, Edison Gonçalves, Jorge O Ricardo-Pérez
This work utilizes a Gabor Holographic Optical Scheme integrated with a microscope objective and a thin convex plane lens. This bi-telecentric lens system corrects spherical aberration from the objective, maintains consistent magnification across various reconstruction distances, and ensures a plane incidence on CMOS. Depending on the focal lengths of the objective and lens, the final image can be enlarged or reduced compared to the classic Gabor system, resulting in high-quality reconstructed phase images without spherical aberration...
May 15, 2024: Heliyon
#15
MULTICENTER STUDY
Abdul Karim Ghaith, Ryan Nguyen, Victor Gabriel El-Hajj, Alaa Montaser, Gaetano De Biase, Krishnan Ravindran, Carlos Perez-Vega, Seung Jin Lee, Asmina Dominari, Umberto Battistin, Paola Suárez-Meade, Charbel Moussalem, Naresh P Patel, Maziyar A Kalani, Michelle J Clarke, Peter S Rose, Mohamad Bydon, Kingsley Abode-Iyamah, Oluwaseun O Akinduro
OBJECTIVE: Chordomas are rare tumors of the skull base and spine believed to arise from the vestiges of the embryonic notochord. These tumors are locally aggressive and frequently recur following resection and adjuvant radiotherapy. Proton therapy has been introduced as a tissue-sparing option because of the higher level of precision that proton-beam techniques offer compared with traditional photon radiotherapy. This study aimed to compare recurrence in patients with chordomas receiving proton versus photon radiotherapy following resection by applying tree-based machine learning models...
May 2024: Neurosurgical Focus
#16
JOURNAL ARTICLE
Himal Suthar, Tomás Manea, Dominic Pak, Megan Woodbury, Stephanie M Eick, Amber Cathey, Deborah J Watkins, Rita S Strakovsky, Brad A Ryva, Subramaniam Pennathur, Lixia Zeng, David Weller, June-Soo Park, Sabrina Smith, Erin DeMicco, Amy Padula, Rebecca C Fry, Bhramar Mukherjee, Andrea Aguiar, Sarah Dee Geiger, Shukhan Ng, Gredia Huerta-Montanez, Carmen Vélez-Vega, Zaira Rosario, Jose F Cordero, Emily Zimmerman, Tracey J Woodruff, Rachel Morello-Frosch, Susan L Schantz, John D Meeker, Akram N Alshawabkeh, Max T Aung
Prenatal per- and poly-fluoroalkyl substances (PFAS) exposure may influence gestational outcomes through bioactive lipids─metabolic and inflammation pathway indicators. We estimated associations between prenatal PFAS exposure and bioactive lipids, measuring 12 serum PFAS and 50 plasma bioactive lipids in 414 pregnant women (median 17.4 weeks' gestation) from three Environmental influences on Child Health Outcomes Program cohorts. Pairwise association estimates across cohorts were obtained through linear mixed models and meta-analysis, adjusting the former for false discovery rates...
May 1, 2024: Environmental Science & Technology
#17
JOURNAL ARTICLE
Alina Díez-Solinska, Olatz Goñi-Balentziaga, Garikoitz Beitia-Oyarzabal, Maider Muñoz-Culla, Oscar Vegas, Garikoitz Azkona
Chronic social stress can increase susceptibility to chronic diseases such as depression. One of the most used models to study the physiological mechanisms and behavioral outcomes of this type of stress is chronic defeat stress (CDS) in male mice. OF1 male mice were subjected to a stress period lasting 18 days. During that time, non-stressed animals were housed in groups. The cluster analysis of the behavioral profile displayed during the first social interaction divided subjects into two groups: active/aggressive (AA) and passive/reactive (PR)...
April 28, 2024: Behavioural Brain Research
#18
JOURNAL ARTICLE
S Blazquez, J Algaba, J M Míguez, C Vega, F J Blas, M M Conde
Clathrate hydrates are vital in energy research and environmental applications. Understanding their stability is crucial for harnessing their potential. In this work, we employ direct coexistence simulations to study finite-size effects in the determination of the three-phase equilibrium temperature (T3) for methane hydrates. Two popular water models, TIP4P/Ice and TIP4P/2005, are employed, exploring various system sizes by varying the number of molecules in the hydrate, liquid, and gas phases. The results reveal that finite-size effects play a crucial role in determining T3...
April 28, 2024: Journal of Chemical Physics
#19
Valentina Martínez-Montoya, Miguel Angel Fonseca-Sánchez, Gerardo Fabian-Morales, Ramiro Vega-Gamas, Gloria Eugenia Queipo-García, Luis Felipe León-Madero, Luz María Sánchez-Sánchez
Osteogenesis imperfecta (OI) is a rare hereditary disorder characterized by bone fragility and frequent fractures. While most cases are attributed to variations in collagen-coding genes COL1A1 and COL1A2 , other genes such as IFITM5 have also been associated with the disease, accounting for up to 5 % of cases. Here, we report a case of a 3-month-old female with a femur fracture and limb deformity. X-rays revealed evidence of osteopenia and previous fractures in the arms, clavicle, ribs, and left limb, alongside prenatal bone deformities detected by ultrasound...
June 2024: Bone Reports
#20
JOURNAL ARTICLE
Ariosky Areces-Gonzalez, Deirel Paz-Linares, Usama Riaz, Ying Wang, Min Li, Fuleah A Razzaq, Jorge F Bosch-Bayard, Eduardo Gonzalez-Moreira, Marlis Ontivero-Ortega, Lidice Galan-Garcia, Eduardo Martínez-Montes, Ludovico Minati, Mitchell J Valdes-Sosa, Maria L Bringas-Vega, Pedro A Valdes-Sosa
We present CiftiStorm, an electrophysiological source imaging (ESI) pipeline incorporating recently developed methods to improve forward and inverse solutions. The CiftiStorm pipeline produces Human Connectome Project (HCP) and megconnectome-compliant outputs from dataset inputs with varying degrees of spatial resolution. The input data can range from low-sensor-density electroencephalogram (EEG) or magnetoencephalogram (MEG) recordings without structural magnetic resonance imaging (sMRI) to high-density EEG/MEG recordings with an HCP multimodal sMRI compliant protocol...
2024: Frontiers in Neuroscience
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