keyword
https://read.qxmd.com/read/38484272/slipping-rib-syndrome-in-childhood-a-case-series
#21
JOURNAL ARTICLE
Víctor Álvarez-Muñoz, Ángeles Prado, Nataliz Vega, David Crehuet, Laura Sánchez, Luis Vega
Among the causes of chest pain, slipping rib has a low prevalence, usually with a history of trauma, and its management is controversial. Slipping rib syndrome should be included in the differential diagnosis of causes of chest pain in children. When not associated with previous trauma and cartilage deformity, it is necessary to consider an alteration in rib development, regardless of the typical traumatic etiology in adults. Here we describe a series of pediatric patients with slipping rib seen at a referral hospital between 2001 and 2022...
March 21, 2024: Archivos Argentinos de Pediatría
https://read.qxmd.com/read/38469305/benchmarking-glycoform-resolved-affinity-separation-mass-spectrometry-assays-for-studying-fc%C3%AE-riiia-binding
#22
JOURNAL ARTICLE
Christoph Gstöttner, Steffen Lippold, Michaela Hook, Feng Yang, Markus Haberger, Manfred Wuhrer, David Falck, Tilman Schlothauer, Elena Domínguez-Vega
The antibody- FcγRIIIa interaction triggers key immunological responses such as antibody dependent cellular cytotoxicity (ADCC), making it highly important for therapeutic mAbs. Due to the direct glycan-glycan interaction with FcγRIIIa receptor, differences in antibody glycosylation can drastically influence the binding affinity. Understanding the differential binding of mAb glycoforms is a very important, yet challenging task due to the co-existence of multiple glycoforms in a sample. Affinity liquid chromatography (AC) and affinity capillary electrophoresis (ACE) hyphenated with mass spectrometry (MS) can provide glycoform-resolved affinity profiles of proteins based on their differences in either dissociation (AC) or equilibrium (ACE) constants...
2024: Frontiers in Immunology
https://read.qxmd.com/read/38457517/spin-orbit-exciton-induced-phonon-chirality-in-a-quantum-magnet
#23
JOURNAL ARTICLE
David Lujan, Jeongheon Choe, Swati Chaudhary, Gaihua Ye, Cynthia Nnokwe, Martin Rodriguez-Vega, Jiaming He, Frank Y Gao, T Nathan Nunley, Edoardo Baldini, Jianshi Zhou, Gregory A Fiete, Rui He, Xiaoqin Li
The interplay of charge, spin, lattice, and orbital degrees of freedom in correlated materials often leads to rich and exotic properties. Recent studies have brought new perspectives to bosonic collective excitations in correlated materials. For example, inelastic neutron scattering experiments revealed non-trivial band topology for magnons and spin-orbit excitons (SOEs) in a quantum magnet CoTiO3 (CTO). Here, we report phonon properties resulting from a combination of strong spin-orbit coupling, large crystal field splitting, and trigonal distortion in CTO...
March 12, 2024: Proceedings of the National Academy of Sciences of the United States of America
https://read.qxmd.com/read/38445953/human-neutrophils-couple-nitric-oxide-production-and-extracellular-traps-formation-in-allergic-asthma
#24
JOURNAL ARTICLE
Pedro Chacón, Antonio Vega-Rioja, Bouchra Doukkali, Alberto Del Valle Rodriguez, Lourdes Fernández-Delgado, Leticia Domínguez-Cereijo, Carmen Segura, Beatriz María Pérez-Machuca, James R Perkins, Rajaa El Bekay, José Antonio Cornejo-García, Nabil Hajji, Javier Monteseirín, David Rivas-Pérez
RATIONALE: Nitric oxide (NO) is elevated in the airways and serum of allergic asthmatic patients, suggesting an important role in asthma. NO production has been widely attributed to the canonical inducible nitric oxide synthase (iNOS). Much effort has been made to inhibit this enzyme with two outcomes: no asthma improvement; and partial NO reduction, suggesting the involvement of an iNOS-independent source. OBJECTIVES: Neutrophils produce NO under inflammatory conditions and their role in asthma has been overlooked...
March 6, 2024: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/38426308/pilot-study-assessing-the-safety-and-acceptance-of-a-novel-virtual-reality-system-to-improve-visual-function
#25
JOURNAL ARTICLE
David P Piñero, Luis Leal-Vega, Ainhoa Molina-Martín, Carlos J Hernández-Rodríguez, Rubén Cuadrado-Asensio, Adrián Martín-Gutiérrez, Juan Francisco Arenillas Lara, María Begoña Coco Martín
PURPOSE: To assess the feasibility of the clinical use of a novel Virtual Reality (VR) training software designed to be used for active vision therapy in amblyopic patients by determining its preliminary safety and acceptance on the visual function of healthy adults. METHODS: Pilot study enrolling 10 individuals (3 men, 7 women, mean age: 31.8 ± 6.5 years) with a best-corrected visual acuity (BCVA) of ≥ .90 (decimal) in both eyes were evaluated before and after 20 minutes of exposure to the NEIVATECH VR system using the HTC Vive Pro Eye head mounted display...
March 1, 2024: Seminars in Ophthalmology
https://read.qxmd.com/read/38423291/safety-of-sting-challenge-test-in-patients-with-clonal-mast-cell-diseases
#26
JOURNAL ARTICLE
Arantza Vega-Castro, Gaspar Dalmau-Duch, Lluís Marquès, David González-de-Olano, Berta Ruiz-León
No abstract text is available yet for this article.
February 27, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38420017/evidence-of-spatial-clustering-of-childhood-acute-lymphoblastic-leukemia-cases-in-greater-mexico-city-report-from-the-mexican-inter-institutional-group-for-the-identification-of-the-causes-of-childhood-leukemia
#27
JOURNAL ARTICLE
David Aldebarán Duarte-Rodríguez, Janet Flores-Lujano, Richard J Q McNally, María Luisa Pérez-Saldivar, Elva Jiménez-Hernández, Jorge Alfonso Martín-Trejo, Laura Eugenia Espinoza-Hernández, Aurora Medina-Sanson, Rogelio Paredes-Aguilera, Laura Elizabeth Merino-Pasaye, Martha Margarita Velázquez-Aviña, José Refugio Torres-Nava, Rosa Martha Espinosa-Elizondo, Raquel Amador-Sánchez, Juan José Dosta-Herrera, Javier Anastacio Mondragón-García, Juana Esther González-Ulibarri, Sofía Irene Martínez-Silva, Gilberto Espinoza-Anrubio, María Minerva Paz-Bribiesca, Perla Salcedo-Lozada, Rodolfo Ángel Landa-García, Rosario Ramírez-Colorado, Luis Hernández-Mora, Marlene Santamaría-Ascencio, Anselmo López-Loyola, Arturo Hermilo Godoy-Esquivel, Luis Ramiro García-López, Alison Ireri Anguiano-Ávalos, Karina Mora-Rico, Alejandro Castañeda-Echevarría, Roberto Rodríguez-Jiménez, José Alberto Cibrian-Cruz, Karina Anastacia Solís-Labastida, Rocío Cárdenas-Cardos, Norma López-Santiago, Luz Victoria Flores-Villegas, José Gabriel Peñaloza-González, Ana Itamar González-Ávila, Martin Sánchez-Ruiz, Roberto Rivera-Luna, Luis Rodolfo Rodríguez-Villalobos, Francisco Hernández-Pérez, Jaime Ángel Olvera-Durán, Luis Rey García-Cortés, Minerva Mata-Rocha, Omar Alejandro Sepúlveda-Robles, Vilma Carolina Bekker-Méndez, Silvia Jiménez-Morales, Jorge Meléndez-Zajgla, Haydée Rosas-Vargas, Elizabeth Vega, Juan Carlos Núñez-Enríquez, Juan Manuel Mejía-Aranguré
BACKGROUND: A heterogeneous geographic distribution of childhood acute lymphoblastic leukemia (ALL) cases has been described, possibly, related to the presence of different environmental factors. The aim of the present study was to explore the geographical distribution of childhood ALL cases in Greater Mexico City (GMC). METHODS: A population-based case-control study was conducted. Children <18 years old, newly diagnosed with ALL and residents of GMC were included...
2024: Frontiers in Oncology
https://read.qxmd.com/read/38395497/clinical-features-of-patients-with-hands-arthralgia-referred-from-primary-care-physicians-to-rheumatologists-a-cohort-study
#28
JOURNAL ARTICLE
Gabriel Figueroa-Parra, Martha Mariana Castañeda-Martinez, Pablo Herrera-Sandate, Diana Daniela Castañeda-Martinez, Jorge Antonio Esquivel-Valerio, David Vega-Morales
PURPOSE: Early referral of patients with suspicious of rheumatoid arthritis (RA) has an impact on prognosis. Our study aimed to evaluate the clinical characteristics of patients with hands arthralgia who were referred from primary care physicians (PCP) to the rheumatologist. METHODS: A descriptive, observational, prospective cohort study was performed. We included patients who visited a PCP for the first time for hands arthralgia. Demographics and the European Alliance of Associations for Rheumatology criteria for arthralgia suspicious for progression to RA plus seven complementary questions, the time to referral, the pressure needed to provoke pain with an automatic squeeze test machine in the metacarpophalangeal joints of both hands, and the diagnoses established at the last review of medical charts from patients on follow-up were documented...
February 2024: Reumatología clinica
https://read.qxmd.com/read/38394587/search-for-scalar-leptoquarks-produced-via-%C3%AF-lepton-quark-scattering-in-pp-collisions-at-sqrt-s-13%C3%A2-%C3%A2-tev
#29
JOURNAL ARTICLE
A Hayrapetyan, A Tumasyan, W Adam, J W Andrejkovic, T Bergauer, S Chatterjee, K Damanakis, M Dragicevic, A Escalante Del Valle, P S Hussain, M Jeitler, N Krammer, D Liko, I Mikulec, J Schieck, R Schöfbeck, D Schwarz, M Sonawane, S Templ, W Waltenberger, C-E Wulz, M R Darwish, T Janssen, P Van Mechelen, E S Bols, J D'Hondt, S Dansana, A De Moor, M Delcourt, H El Faham, S Lowette, I Makarenko, D Müller, A R Sahasransu, S Tavernier, M Tytgat, S Van Putte, D Vannerom, B Clerbaux, G De Lentdecker, L Favart, D Hohov, J Jaramillo, A Khalilzadeh, K Lee, M Mahdavikhorrami, A Malara, S Paredes, L Pétré, N Postiau, L Thomas, M Vanden Bemden, C Vander Velde, P Vanlaer, M De Coen, D Dobur, Y Hong, J Knolle, L Lambrecht, G Mestdach, C Rendón, A Samalan, K Skovpen, N Van Den Bossche, L Wezenbeek, A Benecke, G Bruno, C Caputo, C Delaere, I S Donertas, A Giammanco, K Jaffel, Sa Jain, V Lemaitre, J Lidrych, P Mastrapasqua, K Mondal, T T Tran, S Wertz, G A Alves, E Coelho, C Hensel, T Menezes De Oliveira, A Moraes, P Rebello Teles, M Soeiro, W L Aldá Júnior, M Alves Gallo Pereira, M Barroso Ferreira Filho, H Brandao Malbouisson, W Carvalho, J Chinellato, E M Da Costa, G G Da Silveira, D De Jesus Damiao, S Fonseca De Souza, J Martins, C Mora Herrera, K Mota Amarilo, L Mundim, H Nogima, A Santoro, S M Silva Do Amaral, A Sznajder, M Thiel, A Vilela Pereira, C A Bernardes, L Calligaris, T R Fernandez Perez Tomei, E M Gregores, P G Mercadante, S F Novaes, B Orzari, Sandra S Padula, A Aleksandrov, G Antchev, R Hadjiiska, P Iaydjiev, M Misheva, M Shopova, G Sultanov, A Dimitrov, T Ivanov, L Litov, B Pavlov, P Petkov, A Petrov, E Shumka, S Keshri, S Thakur, T Cheng, Q Guo, T Javaid, M Mittal, L Yuan, G Bauer, Z Hu, J Liu, K Yi, G M Chen, H S Chen, M Chen, F Iemmi, C H Jiang, A Kapoor, H Liao, Z-A Liu, F Monti, M A Shahzad, R Sharma, J N Song, J Tao, C Wang, J Wang, Z Wang, H Zhang, A Agapitos, Y Ban, A Levin, C Li, Q Li, Y Mao, S J Qian, X Sun, D Wang, H Yang, L Zhang, C Zhou, Z You, N Lu, X Gao, D Leggat, H Okawa, Y Zhang, Z Lin, C Lu, M Xiao, C Avila, D A Barbosa Trujillo, A Cabrera, C Florez, J Fraga, J A Reyes Vega, J Mejia Guisao, F Ramirez, M Rodriguez, J D Ruiz Alvarez, D Giljanovic, N Godinovic, D Lelas, A Sculac, M Kovac, T Sculac, P Bargassa, V Brigljevic, B K Chitroda, D Ferencek, S Mishra, A Starodumov, T Susa, A Attikis, K Christoforou, S Konstantinou, J Mousa, C Nicolaou, F Ptochos, P A Razis, H Rykaczewski, H Saka, A Stepennov, M Finger, M Finger, A Kveton, E Ayala, E Carrera Jarrin, Y Assran, S Elgammal, M Abdullah Al-Mashad, M A Mahmoud, R K Dewanjee, K Ehataht, M Kadastik, T Lange, S Nandan, C Nielsen, J Pata, M Raidal, L Tani, C Veelken, H Kirschenmann, K Osterberg, M Voutilainen, S Bharthuar, E Brücken, F Garcia, J Havukainen, K T S Kallonen, M S Kim, R Kinnunen, T Lampén, K Lassila-Perini, S Lehti, T Lindén, M Lotti, L Martikainen, M Myllymäki, M M Rantanen, H Siikonen, E Tuominen, J Tuominiemi, P Luukka, H Petrow, T Tuuva, M Besancon, F Couderc, M Dejardin, D Denegri, J L Faure, F Ferri, S Ganjour, P Gras, G Hamel de Monchenault, V Lohezic, J Malcles, J Rander, A Rosowsky, M Ö Sahin, A Savoy-Navarro, P Simkina, M Titov, C Baldenegro Barrera, F Beaudette, A Buchot Perraguin, P Busson, A Cappati, C Charlot, F Damas, O Davignon, A De Wit, G Falmagne, B A Fontana Santos Alves, S Ghosh, A Gilbert, R Granier de Cassagnac, A Hakimi, B Harikrishnan, L Kalipoliti, G Liu, J Motta, M Nguyen, C Ochando, L Portales, R Salerno, U Sarkar, J B Sauvan, Y Sirois, A Tarabini, E Vernazza, A Zabi, A Zghiche, J-L Agram, J Andrea, D Apparu, D Bloch, J-M Brom, E C Chabert, C Collard, S Falke, U Goerlach, C Grimault, R Haeberle, A-C Le Bihan, M A Sessini, P Van Hove, S Beauceron, B Blancon, G Boudoul, N Chanon, J Choi, D Contardo, P Depasse, C Dozen, H El Mamouni, J Fay, S Gascon, M Gouzevitch, C Greenberg, G Grenier, B Ille, I B Laktineh, M Lethuillier, L Mirabito, S Perries, A Purohit, M Vander Donckt, P Verdier, J Xiao, A Khvedelidze, I Lomidze, Z Tsamalaidze, V Botta, L Feld, K Klein, M Lipinski, D Meuser, A Pauls, N Röwert, M Teroerde, S Diekmann, A Dodonova, N Eich, D Eliseev, F Engelke, M Erdmann, P Fackeldey, B Fischer, T Hebbeker, K Hoepfner, F Ivone, A Jung, M Y Lee, L Mastrolorenzo, M Merschmeyer, A Meyer, S Mukherjee, D Noll, A Novak, F Nowotny, A Pozdnyakov, Y Rath, W Redjeb, F Rehm, H Reithler, V Sarkisovi, A Schmidt, S C Schuler, A Sharma, A Stein, F Torres Da Silva De Araujo, L Vigilante, S Wiedenbeck, S Zaleski, C Dziwok, G Flügge, W Haj Ahmad, T Kress, A Nowack, O Pooth, A Stahl, T Ziemons, A Zotz, H Aarup Petersen, M Aldaya Martin, J Alimena, S Amoroso, Y An, S Baxter, M Bayatmakou, H Becerril Gonzalez, O Behnke, A Belvedere, S Bhattacharya, F Blekman, K Borras, D Brunner, A Campbell, A Cardini, C Cheng, F Colombina, S Consuegra Rodríguez, G Correia Silva, M De Silva, G Eckerlin, D Eckstein, L I Estevez Banos, O Filatov, E Gallo, A Geiser, A Giraldi, G Greau, V Guglielmi, M Guthoff, A Hinzmann, A Jafari, L Jeppe, N Z Jomhari, B Kaech, M Kasemann, H Kaveh, C Kleinwort, R Kogler, M Komm, D Krücker, W Lange, D Leyva Pernia, K Lipka, W Lohmann, R Mankel, I-A Melzer-Pellmann, M Mendizabal Morentin, J Metwally, A B Meyer, G Milella, A Mussgiller, A Nürnberg, Y Otarid, D Pérez Adán, E Ranken, A Raspereza, B Ribeiro Lopes, J Rübenach, A Saggio, M Scham, S Schnake, P Schütze, C Schwanenberger, D Selivanova, M Shchedrolosiev, R E Sosa Ricardo, L P Sreelatha Pramod, D Stafford, F Vazzoler, A Ventura Barroso, R Walsh, Q Wang, Y Wen, K Wichmann, L Wiens, C Wissing, S Wuchterl, Y Yang, A Zimermmane Castro Santos, A Albrecht, S Albrecht, M Antonello, S Bein, L Benato, M Bonanomi, P Connor, M Eich, K El Morabit, Y Fischer, A Fröhlich, C Garbers, E Garutti, A Grohsjean, M Hajheidari, J Haller, H R Jabusch, G Kasieczka, P Keicher, R Klanner, W Korcari, T Kramer, V Kutzner, F Labe, J Lange, A Lobanov, C Matthies, A Mehta, L Moureaux, M Mrowietz, A Nigamova, Y Nissan, A Paasch, K J Pena Rodriguez, T Quadfasel, B Raciti, M Rieger, D Savoiu, J Schindler, P Schleper, M Schröder, J Schwandt, M Sommerhalder, H Stadie, G Steinbrück, A Tews, M Wolf, S Brommer, M Burkart, E Butz, T Chwalek, A Dierlamm, A Droll, N Faltermann, M Giffels, A Gottmann, F Hartmann, R Hofsaess, M Horzela, U Husemann, M Klute, R Koppenhöfer, M Link, A Lintuluoto, S Maier, S Mitra, M Mormile, Th Müller, M Neukum, M Oh, G Quast, K Rabbertz, B Regnery, N Shadskiy, I Shvetsov, H J Simonis, N Trevisani, R Ulrich, J van der Linden, R F Von Cube, M Wassmer, S Wieland, F Wittig, R Wolf, S Wunsch, X Zuo, G Anagnostou, P Assiouras, G Daskalakis, A Kyriakis, A Papadopoulos, A Stakia, P Kontaxakis, G Melachroinos, A Panagiotou, I Papavergou, I Paraskevas, N Saoulidou, K Theofilatos, E Tziaferi, K Vellidis, I Zisopoulos, G Bakas, T Chatzistavrou, G Karapostoli, K Kousouris, I Papakrivopoulos, E Siamarkou, G Tsipolitis, A Zacharopoulou, K Adamidis, I Bestintzanos, I Evangelou, C Foudas, P Gianneios, C Kamtsikis, P Katsoulis, P Kokkas, P G Kosmoglou Kioseoglou, N Manthos, I Papadopoulos, J Strologas, M Csanád, K Farkas, M M A Gadallah, Á Kadlecsik, P Major, K Mandal, G Pásztor, A J Rádl, G I Veres, M Bartók, C Hajdu, D Horvath, F Sikler, V Veszpremi, P Raics, B Ujvari, G Zilizi, G Bencze, S Czellar, J Karancsi, J Molnar, Z Szillasi, T Csorgo, F Nemes, T Novak, J Babbar, S Bansal, S B Beri, V Bhatnagar, G Chaudhary, S Chauhan, N Dhingra, R Gupta, A Kaur, A Kaur, H Kaur, M Kaur, S Kumar, M Meena, K Sandeep, T Sheokand, J B Singh, A Singla, A Ahmed, A Bhardwaj, A Chhetri, B C Choudhary, A Kumar, M Naimuddin, K Ranjan, S Saumya, S Acharya, S Baradia, S Barman, S Bhattacharya, D Bhowmik, S Dutta, S Dutta, B Gomber, P Palit, G Saha, B Sahu, S Sarkar, M M Ameen, P K Behera, S C Behera, S Chatterjee, P Jana, P Kalbhor, J R Komaragiri, D Kumar, L Panwar, R Pradhan, P R Pujahari, N R Saha, A Sharma, A K Sikdar, S Verma, T Aziz, I Das, S Dugad, M Kumar, G B Mohanty, P Suryadevara, A Bala, S Banerjee, R M Chatterjee, M Guchait, Sh Jain, S Karmakar, S Kumar, G Majumder, K Mazumdar, S Mukherjee, S Parolia, A Thachayath, S Bahinipati, A K Das, C Kar, D Maity, P Mal, T Mishra, V K Muraleedharan Nair Bindhu, K Naskar, A Nayak, P Sadangi, P Saha, S K Swain, S Varghese, D Vats, A Alpana, S Dube, B Kansal, A Laha, A Rastogi, S Sharma, H Bakhshiansohi, E Khazaie, M Zeinali, S Chenarani, S M Etesami, M Khakzad, M Mohammadi Najafabadi, M Grunewald, M Abbrescia, R Aly, A Colaleo, D Creanza, B D' Anzi, N De Filippis, M De Palma, A Di Florio, W Elmetenawee, L Fiore, G Iaselli, G Maggi, M Maggi, I Margjeka, V Mastrapasqua, S My, S Nuzzo, A Pellecchia, A Pompili, G Pugliese, R Radogna, G Ramirez-Sanchez, D Ramos, A Ranieri, L Silvestris, F M Simone, Ü Sözbilir, A Stamerra, R Venditti, P Verwilligen, A Zaza, G Abbiendi, C Battilana, L Borgonovi, R Campanini, P Capiluppi, A Castro, F R Cavallo, M Cuffiani, G M Dallavalle, T Diotalevi, F Fabbri, A Fanfani, D Fasanella, P Giacomelli, L Giommi, C Grandi, L Guiducci, S Lo Meo, L Lunerti, S Marcellini, G Masetti, F L Navarria, A Perrotta, F Primavera, A M Rossi, T Rovelli, G P Siroli, S Costa, A Di Mattia, R Potenza, A Tricomi, C Tuve, G Barbagli, G Bardelli, B Camaiani, A Cassese, R Ceccarelli, V Ciulli, C Civinini, R D'Alessandro, E Focardi, T Kello, G Latino, P Lenzi, M Lizzo, M Meschini, S Paoletti, A Papanastassiou, G Sguazzoni, L Viliani, L Benussi, S Bianco, S Meola, D Piccolo, P Chatagnon, F Ferro, E Robutti, S Tosi, A Benaglia, G Boldrini, F Brivio, F Cetorelli, F De Guio, M E Dinardo, P Dini, S Gennai, R Gerosa, A Ghezzi, P Govoni, L Guzzi, M T Lucchini, M Malberti, S Malvezzi, A Massironi, D Menasce, L Moroni, M Paganoni, D Pedrini, B S Pinolini, S Ragazzi, T Tabarelli de Fatis, D Zuolo, S Buontempo, A Cagnotta, F Carnevali, N Cavallo, A De Iorio, F Fabozzi, A O M Iorio, L Lista, P Paolucci, B Rossi, C Sciacca, R Ardino, P Azzi, N Bacchetta, D Bisello, P Bortignon, A Bragagnolo, R Carlin, P Checchia, T Dorigo, S Fantinel, F Fanzago, U Gasparini, G Grosso, L Layer, E Lusiani, M Margoni, M Migliorini, J Pazzini, P Ronchese, R Rossin, F Simonetto, G Strong, M Tosi, A Triossi, S Ventura, H Yarar, M Zanetti, P Zotto, A Zucchetta, G Zumerle, S Abu Zeid, C Aimè, A Braghieri, S Calzaferri, D Fiorina, P Montagna, V Re, C Riccardi, P Salvini, I Vai, P Vitulo, S Ajmal, P Asenov, G M Bilei, D Ciangottini, L Fanò, M Magherini, G Mantovani, V Mariani, M Menichelli, F Moscatelli, A Piccinelli, M Presilla, A Rossi, A Santocchia, D Spiga, T Tedeschi, P Azzurri, G Bagliesi, R Bhattacharya, L Bianchini, T Boccali, E Bossini, D Bruschini, R Castaldi, M A Ciocci, M Cipriani, V D'Amante, R Dell'Orso, S Donato, A Giassi, F Ligabue, D Matos Figueiredo, A Messineo, M Musich, F Palla, A Rizzi, G Rolandi, S Roy Chowdhury, T Sarkar, A Scribano, P Spagnolo, R Tenchini, G Tonelli, N Turini, A Venturi, P G Verdini, P Barria, M Campana, F Cavallari, L Cunqueiro Mendez, D Del Re, E Di Marco, M Diemoz, F Errico, E Longo, P Meridiani, J Mijuskovic, G Organtini, F Pandolfi, R Paramatti, C Quaranta, S Rahatlou, C Rovelli, F Santanastasio, L Soffi, N Amapane, R Arcidiacono, S Argiro, M Arneodo, N Bartosik, R Bellan, A Bellora, C Biino, N Cartiglia, M Costa, R Covarelli, N Demaria, L Finco, M Grippo, B Kiani, F Legger, F Luongo, C Mariotti, S Maselli, A Mecca, E Migliore, M Monteno, R Mulargia, M M Obertino, G Ortona, L Pacher, N Pastrone, M Pelliccioni, M Ruspa, F Siviero, V Sola, A Solano, D Soldi, A Staiano, C Tarricone, M Tornago, D Trocino, G Umoret, E Vlasov, S Belforte, V Candelise, M Casarsa, F Cossutti, K De Leo, G Della Ricca, S Dogra, J Hong, C Huh, B Kim, D H Kim, J Kim, H Lee, S W Lee, C S Moon, Y D Oh, M S Ryu, S Sekmen, Y C Yang, G Bak, P Gwak, H Kim, D H Moon, E Asilar, D Kim, T J Kim, J A Merlin, J Park, S Choi, S Han, B Hong, K Lee, K S Lee, S Lee, J Park, S K Park, J Yoo, J Goh, H S Kim, Y Kim, S Lee, J Almond, J H Bhyun, J Choi, W Jun, J Kim, J S Kim, S Ko, H Kwon, H Lee, J Lee, J Lee, B H Oh, S B Oh, H Seo, U K Yang, I Yoon, W Jang, D Y Kang, Y Kang, S Kim, B Ko, J S H Lee, Y Lee, I C Park, Y Roh, I J Watson, S Yang, S Ha, H D Yoo, M Choi, M R Kim, H Lee, Y Lee, I Yu, T Beyrouthy, Y Maghrbi, K Dreimanis, A Gaile, G Pikurs, A Potrebko, M Seidel, V Veckalns, N R Strautnieks, M Ambrozas, A Juodagalvis, A Rinkevicius, G Tamulaitis, N Bin Norjoharuddeen, I Yusuff, Z Zolkapli, J F Benitez, A Castaneda Hernandez, H A Encinas Acosta, L G Gallegos Maríñez, M León Coello, J A Murillo Quijada, A Sehrawat, L Valencia Palomo, G Ayala, H Castilla-Valdez, E De La Cruz-Burelo, I Heredia-De La Cruz, R Lopez-Fernandez, C A Mondragon Herrera, A Sánchez Hernández, C Oropeza Barrera, M Ramírez García, I Bautista, I Pedraza, H A Salazar Ibarguen, C Uribe Estrada, I Bubanja, N Raicevic, P H Butler, A Ahmad, M I Asghar, A Awais, M I M Awan, H R Hoorani, W A Khan, V Avati, L Grzanka, M Malawski, H Bialkowska, M Bluj, B Boimska, M Górski, M Kazana, M Szleper, P Zalewski, K Bunkowski, K Doroba, A Kalinowski, M Konecki, J Krolikowski, A Muhammad, M Araujo, D Bastos, C Beirão Da Cruz E Silva, A Boletti, M Bozzo, P Faccioli, M Gallinaro, J Hollar, N Leonardo, T Niknejad, A Petrilli, M Pisano, J Seixas, J Varela, J W Wulff, P Adzic, P Milenovic, M Dordevic, J Milosevic, V Rekovic, M Aguilar-Benitez, J Alcaraz Maestre, Cristina F Bedoya, M Cepeda, M Cerrada, N Colino, B De La Cruz, A Delgado Peris, D Fernández Del Val, J P Fernández Ramos, J Flix, M C Fouz, O Gonzalez Lopez, S Goy Lopez, J M Hernandez, M I Josa, J León Holgado, D Moran, C M Morcillo Perez, Á Navarro Tobar, C Perez Dengra, A Pérez-Calero Yzquierdo, J Puerta Pelayo, I Redondo, D D Redondo Ferrero, L Romero, S Sánchez Navas, L Urda Gómez, J Vazquez Escobar, C Willmott, J F de Trocóniz, B Alvarez Gonzalez, J Cuevas, J Fernandez Menendez, S Folgueras, I Gonzalez Caballero, J R González Fernández, E Palencia Cortezon, C Ramón Álvarez, V Rodríguez Bouza, A Soto Rodríguez, A Trapote, C Vico Villalba, P Vischia, S Bhowmik, S Blanco Fernández, J A Brochero Cifuentes, I J Cabrillo, A Calderon, J Duarte Campderros, M Fernandez, C Fernandez Madrazo, G Gomez, C Lasaosa García, C Martinez Rivero, P Martinez Ruiz Del Arbol, F Matorras, P Matorras Cuevas, E Navarrete Ramos, J Piedra Gomez, L Scodellaro, I Vila, J M Vizan Garcia, M K Jayananda, B Kailasapathy, D U J Sonnadara, D D C Wickramarathna, W G D Dharmaratna, K Liyanage, N Perera, N Wickramage, D Abbaneo, C Amendola, E Auffray, G Auzinger, J Baechler, D Barney, A Bermúdez Martínez, M Bianco, B Bilin, A A Bin Anuar, A Bocci, E Brondolin, C Caillol, T Camporesi, G Cerminara, N Chernyavskaya, D d'Enterria, A Dabrowski, A David, A De Roeck, M M Defranchis, M Deile, M Dobson, F Fallavollita, L Forthomme, G Franzoni, W Funk, S Giani, D Gigi, K Gill, F Glege, L Gouskos, M Haranko, J Hegeman, B Huber, V Innocente, T James, P Janot, J Kieseler, S Laurila, P Lecoq, E Leutgeb, C Lourenço, B Maier, L Malgeri, M Mannelli, A C Marini, M Matthewman, F Meijers, S Mersi, E Meschi, V Milosevic, F Moortgat, M Mulders, S Orfanelli, F Pantaleo, M Peruzzi, G Petrucciani, A Pfeiffer, M Pierini, D Piparo, H Qu, D Rabady, G Reales Gutiérrez, M Rovere, H Sakulin, S Scarfi, M Selvaggi, A Sharma, K Shchelina, P Silva, P Sphicas, A G Stahl Leiton, A Steen, S Summers, D Treille, P Tropea, A Tsirou, D Walter, J Wanczyk, K A Wozniak, P Zehetner, P Zejdl, W D Zeuner, T Bevilacqua, L Caminada, A Ebrahimi, W Erdmann, R Horisberger, Q Ingram, H C Kaestli, D Kotlinski, C Lange, M Missiroli, L Noehte, T Rohe, T K Aarrestad, K Androsov, M Backhaus, A Calandri, C Cazzaniga, K Datta, A De Cosa, G Dissertori, M Dittmar, M Donegà, F Eble, M Galli, K Gedia, F Glessgen, C Grab, D Hits, W Lustermann, A-M Lyon, R A Manzoni, M Marchegiani, L Marchese, C Martin Perez, A Mascellani, F Nessi-Tedaldi, F Pauss, V Perovic, S Pigazzini, M G Ratti, M Reichmann, C Reissel, T Reitenspiess, B Ristic, F Riti, D Ruini, D A Sanz Becerra, R Seidita, J Steggemann, D Valsecchi, R Wallny, C Amsler, P Bärtschi, C Botta, D Brzhechko, M F Canelli, K Cormier, R Del Burgo, J K Heikkilä, M Huwiler, W Jin, A Jofrehei, B Kilminster, S Leontsinis, S P Liechti, A Macchiolo, P Meiring, V M Mikuni, U Molinatti, I Neutelings, A Reimers, P Robmann, S Sanchez Cruz, K Schweiger, M Senger, Y Takahashi, R Tramontano, C Adloff, C M Kuo, W Lin, P K Rout, P C Tiwari, S S Yu, L Ceard, Y Chao, K F Chen, P S Chen, Z G Chen, W-S Hou, T H Hsu, Y W Kao, R Khurana, G Kole, Y Y Li, R-S Lu, E Paganis, A Psallidas, X F Su, J Thomas-Wilsker, L S Tsai, H Y Wu, E Yazgan, C Asawatangtrakuldee, N Srimanobhas, V Wachirapusitanand, D Agyel, F Boran, Z S Demiroglu, F Dolek, I Dumanoglu, E Eskut, Y Guler, E Gurpinar Guler, C Isik, O Kara, A Kayis Topaksu, U Kiminsu, G Onengut, K Ozdemir, A Polatoz, B Tali, U G Tok, S Turkcapar, E Uslan, I S Zorbakir, M Yalvac, B Akgun, I O Atakisi, E Gülmez, M Kaya, O Kaya, S Tekten, A Cakir, K Cankocak, Y Komurcu, S Sen, O Aydilek, S Cerci, V Epshteyn, B Hacisahinoglu, I Hos, B Isildak, B Kaynak, S Ozkorucuklu, O Potok, H Sert, C Simsek, D Sunar Cerci, C Zorbilmez, A Boyaryntsev, B Grynyov, L Levchuk, D Anthony, J J Brooke, A Bundock, F Bury, E Clement, D Cussans, H Flacher, M Glowacki, J Goldstein, H F Heath, L Kreczko, B Krikler, S Paramesvaran, S Seif El Nasr-Storey, V J Smith, N Stylianou, K Walkingshaw Pass, R White, A H Ball, K W Bell, A Belyaev, C Brew, R M Brown, D J A Cockerill, C Cooke, K V Ellis, K Harder, S Harper, M-L Holmberg, J Linacre, K Manolopoulos, D M Newbold, E Olaiya, D Petyt, T Reis, G Salvi, T Schuh, C H Shepherd-Themistocleous, I R Tomalin, T Williams, R Bainbridge, P Bloch, C E Brown, O Buchmuller, V Cacchio, C A Carrillo Montoya, G S Chahal, D Colling, J S Dancu, P Dauncey, G Davies, J Davies, M Della Negra, S Fayer, G Fedi, G Hall, M H Hassanshahi, A Howard, G Iles, M Knight, J Langford, L Lyons, A-M Magnan, S Malik, A Martelli, M Mieskolainen, J Nash, M Pesaresi, B C Radburn-Smith, A Richards, A Rose, C Seez, R Shukla, A Tapper, K Uchida, G P Uttley, L H Vage, T Virdee, M Vojinovic, N Wardle, D Winterbottom, K Coldham, J E Cole, A Khan, P Kyberd, I D Reid, S Abdullin, A Brinkerhoff, B Caraway, J Dittmann, K Hatakeyama, J Hiltbrand, A R Kanuganti, B McMaster, M Saunders, S Sawant, C Sutantawibul, M Toms, J Wilson, R Bartek, A Dominguez, C Huerta Escamilla, A E Simsek, R Uniyal, A M Vargas Hernandez, R Chudasama, S I Cooper, S V Gleyzer, C U Perez, P Rumerio, E Usai, C West, R Yi, A Akpinar, A Albert, D Arcaro, C Cosby, Z Demiragli, C Erice, E Fontanesi, D Gastler, S Jeon, J Rohlf, K Salyer, D Sperka, D Spitzbart, I Suarez, A Tsatsos, S Yuan, G Benelli, X Coubez, D Cutts, M Hadley, U Heintz, J M Hogan, T Kwon, G Landsberg, K T Lau, D Li, J Luo, S Mondal, M Narain, N Pervan, S Sagir, F Simpson, M Stamenkovic, W Y Wong, X Yan, W Zhang, S Abbott, J Bonilla, C Brainerd, R Breedon, M Calderon De La Barca Sanchez, M Chertok, M Citron, J Conway, P T Cox, R Erbacher, F Jensen, O Kukral, G Mocellin, M Mulhearn, D Pellett, W Wei, Y Yao, F Zhang, M Bachtis, R Cousins, A Datta, J Hauser, M Ignatenko, M A Iqbal, T Lam, E Manca, W A Nash, D Saltzberg, B Stone, V Valuev, R Clare, M Gordon, G Hanson, W Si, S Wimpenny, J G Branson, S Cittolin, S Cooperstein, D Diaz, J Duarte, L Giannini, J Guiang, R Kansal, V Krutelyov, R Lee, J Letts, M Masciovecchio, F Mokhtar, M Pieri, M Quinnan, B V Sathia Narayanan, V Sharma, M Tadel, E Vourliotis, F Würthwein, Y Xiang, A Yagil, A Barzdukas, L Brennan, C Campagnari, G Collura, A Dorsett, J Incandela, M Kilpatrick, J Kim, A J Li, P Masterson, H Mei, M Oshiro, J Richman, U Sarica, R Schmitz, F Setti, J Sheplock, D Stuart, S Wang, A Bornheim, O Cerri, A Latorre, J M Lawhorn, J Mao, H B Newman, T Q Nguyen, M Spiropulu, J R Vlimant, C Wang, S Xie, R Y Zhu, J Alison, S An, M B Andrews, P Bryant, V Dutta, T Ferguson, A Harilal, C Liu, T Mudholkar, S Murthy, M Paulini, A Roberts, A Sanchez, W Terrill, J P Cumalat, W T Ford, A Hassani, G Karathanasis, E MacDonald, N Manganelli, F Marini, A Perloff, C Savard, N Schonbeck, K Stenson, K A Ulmer, S R Wagner, N Zipper, J Alexander, S Bright-Thonney, X Chen, D J Cranshaw, J Fan, X Fan, D Gadkari, S Hogan, J Monroy, J R Patterson, J Reichert, M Reid, A Ryd, J Thom, P Wittich, R Zou, M Albrow, M Alyari, O Amram, G Apollinari, A Apresyan, L A T Bauerdick, D Berry, J Berryhill, P C Bhat, K Burkett, J N Butler, A Canepa, G B Cerati, H W K Cheung, F Chlebana, G Cummings, J Dickinson, I Dutta, V D Elvira, Y Feng, J Freeman, A Gandrakota, Z Gecse, L Gray, D Green, A Grummer, S Grünendahl, D Guerrero, O Gutsche, R M Harris, R Heller, T C Herwig, J Hirschauer, L Horyn, B Jayatilaka, S Jindariani, M Johnson, U Joshi, T Klijnsma, B Klima, K H M Kwok, S Lammel, D Lincoln, R Lipton, T Liu, C Madrid, K Maeshima, C Mantilla, D Mason, P McBride, P Merkel, S Mrenna, S Nahn, J Ngadiuba, D Noonan, V Papadimitriou, N Pastika, K Pedro, C Pena, F Ravera, A Reinsvold Hall, L Ristori, E Sexton-Kennedy, N Smith, A Soha, L Spiegel, S Stoynev, L Taylor, S Tkaczyk, N V Tran, L Uplegger, E W Vaandering, I Zoi, C Aruta, P Avery, D Bourilkov, L Cadamuro, P Chang, V Cherepanov, R D Field, E Koenig, M Kolosova, J Konigsberg, A Korytov, K H Lo, K Matchev, N Menendez, G Mitselmakher, K Mohrman, A Muthirakalayil Madhu, N Rawal, D Rosenzweig, S Rosenzweig, K Shi, J Wang, T Adams, A Al Kadhim, A Askew, N Bower, R Habibullah, V Hagopian, R Hashmi, R S Kim, S Kim, T Kolberg, G Martinez, H Prosper, P R Prova, O Viazlo, M Wulansatiti, R Yohay, J Zhang, B Alsufyani, M M Baarmand, S Butalla, T Elkafrawy, M Hohlmann, R Kumar Verma, M Rahmani, M R Adams, C Bennett, R Cavanaugh, S Dittmer, R Escobar Franco, O Evdokimov, C E Gerber, D J Hofman, J H Lee, D S Lemos, A H Merrit, C Mills, S Nanda, G Oh, B Ozek, D Pilipovic, T Roy, S Rudrabhatla, M B Tonjes, N Varelas, X Wang, Z Ye, J Yoo, M Alhusseini, D Blend, K Dilsiz, L Emediato, G Karaman, O K Köseyan, J-P Merlo, A Mestvirishvili, J Nachtman, O Neogi, H Ogul, Y Onel, A Penzo, C Snyder, E Tiras, B Blumenfeld, L Corcodilos, J Davis, A V Gritsan, L Kang, S Kyriacou, P Maksimovic, M Roguljic, J Roskes, S Sekhar, M Swartz, T Á Vámi, A Abreu, L F Alcerro Alcerro, J Anguiano, P Baringer, A Bean, Z Flowers, D Grove, J King, G Krintiras, M Lazarovits, C Le Mahieu, C Lindsey, J Marquez, N Minafra, M Murray, M Nickel, M Pitt, S Popescu, C Rogan, C Royon, R Salvatico, S Sanders, C Smith, Q Wang, G Wilson, B Allmond, A Ivanov, K Kaadze, A Kalogeropoulos, D Kim, Y Maravin, K Nam, J Natoli, D Roy, G Sorrentino, F Rebassoo, D Wright, E Adams, A Baden, O Baron, A Belloni, A Bethani, Y M Chen, S C Eno, N J Hadley, S Jabeen, R G Kellogg, T Koeth, Y Lai, S Lascio, A C Mignerey, S Nabili, C Palmer, C Papageorgakis, M M Paranjpe, L Wang, K Wong, J Bendavid, W Busza, I A Cali, Y Chen, M D'Alfonso, J Eysermans, C Freer, G Gomez-Ceballos, M Goncharov, P Harris, D Hoang, D Kovalskyi, J Krupa, L Lavezzo, Y-J Lee, K Long, C Mironov, C Paus, D Rankin, C Roland, G Roland, S Rothman, Z Shi, G S F Stephans, J Wang, Z Wang, B Wyslouch, T J Yang, B Crossman, B M Joshi, C Kapsiak, M Krohn, D Mahon, J Mans, B Marzocchi, S Pandey, M Revering, R Rusack, R Saradhy, N Schroeder, N Strobbe, M A Wadud, L M Cremaldi, K Bloom, M Bryson, D R Claes, C Fangmeier, F Golf, G Haza, J Hossain, C Joo, I Kravchenko, I Reed, J E Siado, W Tabb, A Vagnerini, A Wightman, F Yan, D Yu, A G Zecchinelli, G Agarwal, H Bandyopadhyay, L Hay, I Iashvili, A Kharchilava, C McLean, M Morris, D Nguyen, S Rappoccio, H Rejeb Sfar, A Williams, G Alverson, E Barberis, Y Haddad, Y Han, A Krishna, J Li, M Lu, G Madigan, R Mccarthy, D M Morse, V Nguyen, T Orimoto, A Parker, L Skinnari, A Tishelman-Charny, B Wang, D Wood, S Bhattacharya, J Bueghly, Z Chen, K A Hahn, Y Liu, Y Miao, D G Monk, M H Schmitt, A Taliercio, M Velasco, R Band, R Bucci, S Castells, M Cremonesi, A Das, R Goldouzian, M Hildreth, K W Ho, K Hurtado Anampa, C Jessop, K Lannon, J Lawrence, N Loukas, L Lutton, J Mariano, N Marinelli, I Mcalister, T McCauley, C Mcgrady, C Moore, Y Musienko, H Nelson, M Osherson, R Ruchti, A Townsend, M Wayne, H Yockey, M Zarucki, L Zygala, A Basnet, B Bylsma, M Carrigan, L S Durkin, C Hill, M Joyce, A Lesauvage, M Nunez Ornelas, K Wei, B L Winer, B R Yates, F M Addesa, H Bouchamaoui, P Das, G Dezoort, P Elmer, A Frankenthal, B Greenberg, N Haubrich, S Higginbotham, G Kopp, S Kwan, D Lange, A Loeliger, D Marlow, I Ojalvo, J Olsen, A Shevelev, D Stickland, C Tully, S Malik, A S Bakshi, V E Barnes, S Chandra, R Chawla, S Das, A Gu, L Gutay, M Jones, A W Jung, D Kondratyev, A M Koshy, M Liu, G Negro, N Neumeister, G Paspalaki, S Piperov, V Scheurer, J F Schulte, M Stojanovic, J Thieman, A K Virdi, F Wang, W Xie, J Dolen, N Parashar, A Pathak, D Acosta, A Baty, T Carnahan, S Dildick, K M Ecklund, P J Fernández Manteca, S Freed, P Gardner, F J M Geurts, A Kumar, W Li, O Miguel Colin, B P Padley, R Redjimi, J Rotter, E Yigitbasi, Y Zhang, A Bodek, P de Barbaro, R Demina, J L Dulemba, C Fallon, A Garcia-Bellido, O Hindrichs, A Khukhunaishvili, P Parygin, E Popova, R Taus, G P Van Onsem, K Goulianos, B Chiarito, J P Chou, Y Gershtein, E Halkiadakis, A Hart, M Heindl, D Jaroslawski, O Karacheban, I Laflotte, A Lath, R Montalvo, K Nash, H Routray, S Salur, S Schnetzer, S Somalwar, R Stone, S A Thayil, S Thomas, J Vora, H Wang, H Acharya, D Ally, A G Delannoy, S Fiorendi, T Holmes, N Karunarathna, L Lee, E Nibigira, S Spanier, D Aebi, M Ahmad, O Bouhali, M Dalchenko, R Eusebi, J Gilmore, T Huang, T Kamon, H Kim, S Luo, S Malhotra, R Mueller, D Overton, D Rathjens, A Safonov, N Akchurin, J Damgov, V Hegde, A Hussain, Y Kazhykarim, K Lamichhane, S W Lee, A Mankel, T Mengke, S Muthumuni, T Peltola, I Volobouev, A Whitbeck, E Appelt, S Greene, A Gurrola, W Johns, R Kunnawalkam Elayavalli, A Melo, F Romeo, P Sheldon, S Tuo, J Velkovska, J Viinikainen, B Cardwell, B Cox, J Hakala, R Hirosky, A Ledovskoy, A Li, C Neu, C E Perez Lara, P E Karchin, A Aravind, S Banerjee, K Black, T Bose, S Dasu, I De Bruyn, P Everaerts, C Galloni, H He, M Herndon, A Herve, C K Koraka, A Lanaro, R Loveless, J Madhusudanan Sreekala, A Mallampalli, A Mohammadi, S Mondal, G Parida, D Pinna, A Savin, V Shang, V Sharma, W H Smith, D Teague, H F Tsoi, W Vetens, A Warden, S Afanasiev, V Andreev, Yu Andreev, T Aushev, M Azarkin, A Babaev, A Belyaev, V Blinov, E Boos, V Borshch, D Budkouski, V Bunichev, M Chadeeva, V Chekhovsky, R Chistov, A Dermenev, T Dimova, D Druzhkin, M Dubinin, L Dudko, A Ershov, G Gavrilov, V Gavrilov, S Gninenko, V Golovtcov, N Golubev, I Golutvin, I Gorbunov, A Gribushin, Y Ivanov, V Kachanov, L Kardapoltsev, V Karjavine, A Karneyeu, V Kim, M Kirakosyan, D Kirpichnikov, M Kirsanov, V Klyukhin, O Kodolova, D Konstantinov, V Korenkov, A Kozyrev, N Krasnikov, A Lanev, P Levchenko, N Lychkovskaya, V Makarenko, A Malakhov, V Matveev, V Murzin, A Nikitenko, S Obraztsov, V Oreshkin, V Palichik, V Perelygin, M Perfilov, S Petrushanko, S Polikarpov, V Popov, O Radchenko, M Savina, V Savrin, V Shalaev, S Shmatov, S Shulha, Y Skovpen, S Slabospitskii, V Smirnov, D Sosnov, V Sulimov, E Tcherniaev, A Terkulov, O Teryaev, I Tlisova, A Toropin, L Uvarov, A Uzunian, A Vorobyev, N Voytishin, B S Yuldashev, A Zarubin, I Zhizhin, A Zhokin
The first search for scalar leptoquarks produced in τ-lepton-quark collisions is presented. It is based on a set of proton-proton collision data recorded with the CMS detector at the LHC at a center-of-mass energy of 13 TeV corresponding to an integrated luminosity of 138  fb^{-1}. The reconstructed final state consists of a jet, significant missing transverse momentum, and a τ lepton reconstructed through its hadronic or leptonic decays. Limits are set on the product of the leptoquark production cross section and branching fraction and interpreted as exclusions in the plane of the leptoquark mass and the leptoquark-τ-quark coupling strength...
February 9, 2024: Physical Review Letters
https://read.qxmd.com/read/38392296/the-hallmarks-of-cervical-cancer-molecular-mechanisms-induced-by-human-papillomavirus
#30
REVIEW
Pedro Rosendo-Chalma, Verónica Antonio-Véjar, Jonnathan Gerardo Ortiz Tejedor, Jose Ortiz Segarra, Bernardo Vega Crespo, Gabriele Davide Bigoni-Ordóñez
Human papillomaviruses (HPVs) and, specifically, high-risk HPVs (HR-HPVs) are identified as necessary factors in the development of cancer of the lower genital tract, with CaCU standing out as the most prevalent tumor. This review summarizes ten mechanisms activated by HR-HPVs during cervical carcinogenesis, which are broadly associated with at least seven of the fourteen distinctive physiological capacities of cancer in the newly established model by Hanahan in 2022. These mechanisms involve infection by human papillomavirus, cellular tropism, genetic predisposition to uterine cervical cancer (CaCU), viral load, viral physical state, regulation of epigenetic mechanisms, loss of function of the E2 protein, deregulated expression of E6/E7 oncogenes, regulation of host cell protein function, and acquisition of the mesenchymal phenotype...
January 27, 2024: Biology
https://read.qxmd.com/read/38388965/increased-expression-of-cd70-in-relapsed-acute-myeloid-leukemia-after-hypomethylating-agents
#31
JOURNAL ARTICLE
Mario L Marques-Piubelli, Bijender Kumar, Rafet Basar, Siler Panowski, Surabhi Srinivasan, Kevin Norwood, Sacha Prashad, Victoria Szenes, Arun Balakumaran, Akanksha Arandhya, Wei Lu, Khaja Khan, Daniela Duenas, Salome McAllen, Javier A Gomez, Jared K Burks, Sunil Acharyal, Gautam Borthakur, Wei-Lien Wang, Wei Wang, Sa Wang, Luisa M Solis, David Marin, Katayoun Rezvani, May Daher, Francisco Vega
Acute myeloid leukemia (AML) is the most common acute leukemia in adults. While induction chemotherapy leads to remission in most patients, a significant number will experience relapse. Therefore, there is a need for novel therapies that can improve remission rates in patients with relapsed and refractory AML. CD70 is the natural ligand for CD27 (a member of the TNF superfamily) and appears to be a promising therapeutic target. Consequently, there is considerable interest in developing chimeric antigen receptor (CAR) T-cell therapy products that can specifically target CD70 in various neoplasms, including AML...
February 22, 2024: Virchows Archiv: An International Journal of Pathology
https://read.qxmd.com/read/38385926/a-prospective-multicenter-real-world-registry-of-coronary-lithotripsy-in-calcified-coronary-arteries-the-replica-epic18-study
#32
JOURNAL ARTICLE
Oriol Rodriguez-Leor, Ana Belen Cid-Alvarez, Maria Lopez-Benito, Nieves Gonzalo, Victoria Vilalta, Jose Antonio Diarte de Miguel, Leticia Fernandez López, Alfonso Jurado-Roman, Alejandro Diego, Juan Francisco Oteo, Carlos Cuellas, Ramiro Trillo, Alejandro Travieso, Fernando Alfonso, Xavier Carrillo, José Miguel Vegas-Valle, Carlos Cortes-Villar, Isaac Pascual, Juan Francisco Muñoz Camacho, Xacobe Flores, Silvio Vera-Vera, Jose Moreu, Gilles Barreira de Sousa, David Martí, Jesus Jimenez-Mazuecos, Monica Fuertes, Raymundo Ocaranza, Jose Maria de la Torre Hernandez, Fernando Lozano, Santiago G Solana Martinez, Josep Gómez-Lara, Armando Perez de Prado
BACKGROUND: Intravascular lithotripsy (IVL) has demonstrated effectiveness in the treatment of calcified lesions in selected patients with stable coronary disease. OBJECTIVES: The authors sought to assess the performance of coronary IVL in calcified coronary lesions in a real-life, all comers, setting. METHODS: The REPLICA-EPIC18 study prospectively enrolled consecutive patients treated with IVL in 26 centers in Spain. An independent core laboratory performed the angiographic analysis and event adjudication...
February 15, 2024: JACC. Cardiovascular Interventions
https://read.qxmd.com/read/38382816/non-binary-gender-vulnerable-populations-and-mental-health-during-the-covid-19-pandemic-data-from-the-covid-19-mental-health-international-for-the-general-population-comet-g-study
#33
JOURNAL ARTICLE
Konstantinos N Fountoulakis, Jelena Vrublevska, Seri Abraham, Kristina Adorjan, Helal Uddin Ahmed, Renato D Alarcón, Kiyomi Arai, Sani Salihu Auwal, Michael Berk, Sarah Bjedov, Julio Bobes, Teresa Bobes-Bascaran, Julie Bourgin-Duchesnay, Cristina Ana Bredicean, Laurynas Bukelskis, Akaki Burkadze, Indira Indiana Cabrera Abud, Ruby Castilla-Puentes, Marcelo Cetkovich, Hector Colon-Rivera, Ricardo Corral, Carla Cortez-Vergara, Piirika Crepin, Domenico De Berardis, Sergio Zamora Delgado, David De Lucena, Avinash De Sousa, Ramona Di Stefano, Seetal Dodd, Livia Priyanka Elek, Anna Elissa, Berta Erdelyi-Hamza, Gamze Erzin, Martin J Etchevers, Peter Falkai, Adriana Farcas, Ilya Fedotov, Viktoriia Filatova, Nikolaos K Fountoulakis, Iryna Frankova, Francesco Franza, Pedro Frias, Tatiana Galako, Cristian J Garay, Leticia Garcia-Álvarez, Maria Paz García-Portilla, Xenia Gonda, Tomasz M Gondek, Daniela Morera González, Hilary Gould, Paolo Grandinetti, Arturo Grau, Violeta Groudeva, Michal Hagin, Takayuki Harada, Tasdik M Hasan, Nurul Azreen Hashim, Jan Hilbig, Sahadat Hossain, Rossitza Iakimova, Mona Ibrahim, Felicia Iftene, Yulia Ignatenko, Matias Irarrazaval, Zaliha Ismail, Jamila Ismayilova, Asaf Jacobs, Miro Jakovljević, Nenad Jakšić, Afzal Javed, Helin Yilmaz Kafali, Sagar Karia, Olga Kazakova, Doaa Khalifa, Olena Khaustova, Steve Koh, Korneliia Kosenko, Sotirios A Koupidis, Alisha Lalljee, Justine Liewig, Abdul Majid, Evgeniia Malashonkova, Khamelia Malik, Najma Iqbal Malik, Gulay Mammadzada, Bilvesh Mandalia, Donatella Marazziti, Darko Marčinko, Stephanie Martinez, Eimantas Matiekus, Gabriela Mejia, Roha Saeed Memon, Xarah Elenne Meza Martínez, Dalia Mickevičiūtė, Roumen Milev, Muftau Mohammed, Alejandro Molina-López, Petr Morozov, Nuru Suleiman Muhammad, Filip Mustač, Mika S Naor, Amira Nassieb, Alvydas Navickas, Tarek Okasha, Milena Pandova, Anca-Livia Panfil, Liliya Panteleeva, Ion Papava, Mikaella E Patsali, Alexey Pavlichenko, Bojana Pejuskovic, Mariana Pinto Da Costa, Mikhail Popkov, Dina Popovic, Nor Jannah Nasution Raduan, Francisca Vargas Ramírez, Elmars Rancans, Salmi Razali, Federico Rebok, Anna Rewekant, Elena Ninoska Reyes Flores, María Teresa Rivera-Encinas, Pilar Saiz, Manuel Sánchez de Carmona, David Saucedo Martínez, Jo Anne Saw, Görkem Saygili, Patricia Schneidereit, Bhumika Shah, Tomohiro Shirasaka, Ketevan Silagadze, Satti Sitanggang, Oleg Skugarevsky, Anna Spikina, Sridevi Sira Mahalingappa, Maria Stoyanova, Anna Szczegielniak, Simona Claudia Tamasan, Giuseppe Tavormina, Maurilio Giuseppe Maria Tavormina, Pavlos N Theodorakis, Mauricio Tohen, Eva Maria Tsapakis, Dina Tukhvatullina, Irfan Ullah, Ratnaraj Vaidya, Johann M Vega-Dienstmaier, Olivera Vukovic, Olga Vysotska, Natalia Widiasih, Anna Yashikhina, Daria Smirnova
BACKGROUND: The COVID-19 pandemic has brought significant mental health challenges, particularly for vulnerable populations, including non-binary gender individuals. The COMET international study aimed to investigate specific risk factors for clinical depression or distress during the pandemic, also in these special populations. METHODS: Chi-square tests were used for initial screening to select only those variables which would show an initial significance. Risk Ratios (RR) were calculated, and a Multiple Backward Stepwise Linear Regression Analysis (MBSLRA) was followed with those variables given significant results at screening and with the presence of distress or depression or the lack of both of them...
February 19, 2024: Journal of Affective Disorders
https://read.qxmd.com/read/38381845/lipocalin-2-expression-identifies-an-intestinal-regulatory-neutrophil-population-during-acute-graft-versus-host-disease
#34
JOURNAL ARTICLE
Marie Czech, Sophia Schneider, Nina Peltokangas, Nadia El Khawanky, Sakhila Ghimire, Geoffroy Andrieux, Jan Hülsdünker, Máté Krausz, Michele Proietti, Lukas M Braun, Tamina Rückert, Marlene Langenbach, Dominik Schmidt, Ina Martin, Valentin Wenger, Enrique de Vega, Eileen Haring, Mohsen Pourjam, Dietmar Pfeifer, Annette Schmitt-Graeff, Bodo Grimbacher, Konrad Aumann, Brigitte Kircher, Herbert Tilg, Manuela Raffatellu, Erik Thiele Orberg, Georg Häcker, Justus Duyster, Natalie Köhler, Ernst Holler, David Nachbaur, Melanie Boerries, Romana R Gerner, Dominic Grün, Robert Zeiser
Acute graft-versus-host disease (aGVHD) is a life-threatening complication of allogeneic hematopoietic cell transplantation (allo-HCT), for which therapeutic options are limited. Strategies to promote intestinal tissue tolerance during aGVHD may improve patient outcomes. Using single-cell RNA sequencing, we identified a lipocalin-2 (LCN2)-expressing neutrophil population in mice with intestinal aGVHD. Transfer of LCN2-overexpressing neutrophils or treatment with recombinant LCN2 reduced aGVHD severity, whereas the lack of epithelial or hematopoietic LCN2 enhanced aGVHD severity and caused microbiome alterations...
February 21, 2024: Science Translational Medicine
https://read.qxmd.com/read/38377140/transmission-ecology-of-trypanosoma-cruzi-by-rhodnius-prolixus-reduviidae-triatominae-infesting-palm-tree-species-in-the-colombian-orinoco-indicates-risks-to-human-populations
#35
JOURNAL ARTICLE
Plutarco Urbano, Carolina Hernández, Natalia Velásquez-Ortiz, Nathalia Ballesteros, Luisa Páez-Triana, Laura Vega, Vanessa Urrea, Angie Ramírez, Marina Muñoz, Carlos N Ibarra-Cerdeña, Camila González, Juan David Ramírez
BACKGROUND: Chagas disease, affecting approximately eight million individuals in tropical regions, is primarily transmitted by vectors. Rhodnius prolixus, a triatomine vector, commonly inhabits in ecotopes with diverse palm tree species, creating optimal conditions for vector proliferation. This study aims to explore the transmission ecology of Trypanosoma cruzi, the causative parasite of Chagas disease, by investigating the feeding patterns and natural infection rates of R. prolixus specimens collected from various wild palm species in the Colombian Orinoco region...
February 20, 2024: PLoS Neglected Tropical Diseases
https://read.qxmd.com/read/38371375/biomarker-selection-depends-on-gene-function-and-organ-the-case-of-the-cytochrome-p450-family-genes-in-freshwater-fish-exposed-to-chronic-pollution
#36
JOURNAL ARTICLE
Jorge Cortés-Miranda, Noemí Rojas-Hernández, Gigliola Muñoz, Sylvia Copaja, Claudio Quezada-Romegialli, David Veliz, Caren Vega-Retter
Pollution and its effects have been of major concern in recent decades. Many strategies and markers have been developed to assess their effects on biota. Cytochrome P450 (CYP) genes have received significant attention in this context because of their relationship with detoxification and activation of exogenous compounds. While their expression has been identified as a pollution exposure biomarker, in most cases, it has been tested only after acute exposures and for CYP genes associated with exogenous compounds...
2024: PeerJ
https://read.qxmd.com/read/38369783/pan-cancer-genomic-analysis-of-axl-mutations-reveals-a-novel-recurrent-functionally-activating-axl-w451c-alteration-specific-to-myxofibrosarcoma
#37
JOURNAL ARTICLE
Erik A Williams, Isabella Vegas, Fardous F El-Senduny, Jessica Zhang, Douglas A Mata, Matthew C Hiemenz, Sarah R Hughes, Brianna C Sa, Garrett P Kraft, Nicole Gorbatov, Kathleen Foley-Peres, Edward Z Sanchez, Clara Milikowski, Kevin Jon Williams, Jeffrey S Ross, Razelle Kurzrock, Elizabeth A Montgomery, David B Lombard, Surinder Kumar
Myxofibrosarcoma (MFS) is a common soft tissue sarcoma of the elderly that typically shows low tumor mutational burden, with mutations in TP53 and in genes associated with cell cycle checkpoints (RB1, CDKN2A). Unfortunately, no alterations or markers specific to MFS have been identified and, as a consequence, there are no effective targeted therapies. The receptor tyrosine kinase AXL, which drives cellular proliferation, is targetable by new antibody-based therapeutics. Expression of AXL messenger RNA is elevated in a variety of sarcoma types, with the highest levels reported in MFS, but the pathogenic significance of this finding remains unknown...
February 19, 2024: American Journal of Surgical Pathology
https://read.qxmd.com/read/38356692/clinical-acceptability-of-automatically-generated-lymph-node-levels-and-structures-of-deglutition-and-mastication-for-head-and-neck-radiation-therapy
#38
JOURNAL ARTICLE
Sean Maroongroge, Abdallah Sr Mohamed, Callistus Nguyen, Jean Guma De la Vega, Steven J Frank, Adam S Garden, Brandon G Gunn, Anna Lee, Lauren Mayo, Amy Moreno, William H Morrison, Jack Phan, Michael T Spiotto, Laurence E Court, Clifton D Fuller, David I Rosenthal, Tucker J Netherton
BACKGROUND AND PURPOSE: Auto-contouring of complex anatomy in computed tomography (CT) scans is a highly anticipated solution to many problems in radiotherapy. In this study, artificial intelligence (AI)-based auto-contouring models were clinically validated for lymph node levels and structures of swallowing and chewing in the head and neck. MATERIALS AND METHODS: CT scans of 145 head and neck radiotherapy patients were retrospectively curated. One cohort (n = 47) was used to analyze seven lymph node levels and the other (n = 98) used to analyze 17 swallowing and chewing structures...
January 2024: Physics and Imaging in Radiation Oncology
https://read.qxmd.com/read/38353071/global-practice-patterns-of-preoperative-image-reconstruction-for-liver-surgery
#39
JOURNAL ARTICLE
Elena Panettieri, Eduardo A Vega, Oscar Salirrosas, Satoshi Ogiso, David Geller, Claudius Conrad
BACKGROUND: Three-dimensional (3-D) liver modeling is used globally; however, its actual practice is limited to a few centers. This study aimed to assess practice patterns and barriers to the use of 3-D modeling among liver surgeons worldwide. METHODS: A survey approved by the International Hepato-Pancreato-Biliary Association research council consisting of 27 questions was conducted using an online questionnaire. Incomplete responses were excluded. RESULTS: Of 235 respondents from 46 countries, 81...
January 2024: Journal of Gastrointestinal Surgery
https://read.qxmd.com/read/38336975/car-t-cell-therapy-targeting-surface-expression-of-tyrp1-to-treat-cutaneous-and-rare-melanoma-subtypes
#40
JOURNAL ARTICLE
Sameeha Jilani, Justin D Saco, Edurne Mugarza, Aleida Pujol-Morcillo, Jeffrey Chokry, Clement Ng, Gabriel Abril-Rodriguez, David Berger-Manerio, Ami Pant, Jane Hu, Rubi Gupta, Agustin Vega-Crespo, Ignacio Baselga-Carretero, Jia M Chen, Daniel Sanghoon Shin, Philip Scumpia, Roxana A Radu, Yvonne Chen, Antoni Ribas, Cristina Puig-Saus
A major limitation to developing chimeric antigen receptor (CAR)-T cell therapies for solid tumors is identifying surface proteins highly expressed in tumors but not in normal tissues. Here, we identify Tyrosinase Related Protein 1 (TYRP1) as a CAR-T cell therapy target to treat patients with cutaneous and rare melanoma subtypes unresponsive to immune checkpoint blockade. TYRP1 is primarily located intracellularly in the melanosomes, with a small fraction being trafficked to the cell surface via vesicular transport...
February 9, 2024: Nature Communications
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