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David Vega

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https://www.readbyqxmd.com/read/28792546/host-plant-driven-transcriptome-plasticity-in-the-salivary-glands-of-the-cabbage-looper-trichoplusia-ni
#1
Loren J Rivera-Vega, David A Galbraith, Christina M Grozinger, Gary W Felton
Generalist herbivores feed on a wide array of plants and need to adapt to varying host qualities and defenses. One of the first insect derived secretions to come in contact with the plant is the saliva. Insect saliva is potentially involved in both the pre-digestion of the host plant as well as induction/suppression of plant defenses, yet how the salivary glands respond to changes in host plant at the transcriptional level is largely unknown. The objective of this study was to determine how the labial salivary gland transcriptome varies according to the host plant on which the insect is feeding...
2017: PloS One
https://www.readbyqxmd.com/read/28739020/a-multimodal-approach-for-myofascial-pain-syndrome-a-prospective-study
#2
María Segura-Pérez, M Teresa Hernández-Criado, César Calvo-Lobo, Lorena Vega-Piris, Raquel Fernández-Martín, David Rodríguez-Sanz
OBJECTIVE: The purpose of this study was to analyze pain intensity in patients with myofascial pain syndrome (MPS) following a multimodal rehabilitation protocol. METHODS: A prospective study was carried out following the Template for Intervention Description and Replication criteria. Patients were recruited from the rehabilitation unit of a university hospital in Spain between 2009 and 2013. Patients were included if they had a medical diagnosis of MPS in any of the following regions: cervicobrachial (n = 102), lumbosacral (n = 30), elbow (n = 14), ankle and foot (n = 10), and temporomandibular jaw (n = 1)...
July 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/28736763/immunologic-effects-of-maraviroc-in-hiv-infected-patients-with-severe-cd4-lymphopenia-starting-antiretroviral-therapy-a-sub-study-of-the-cadiris-trial
#3
Pablo F Belaunzarán-Zamudio, Livio Azzoni, David H Canaday, Yanink N Caro-Vega, Brian Clagget, Mohammed S Rassool, Benigno Rodriguez, Ian Sanne, Irini Sereti, Juan G Sierra-Madero, Michael M Lederman
BACKGROUND: We aimed to describe the mechanisms of immunological recovery and the effects of blocking CCR5 in patients starting ART with advanced HIV-infection. METHODS: This was a sub-study of a 48 week double-blind, clinical trial where patients starting ART with CD4+ cell counts <100 cells/uL were randomized to receive maraviroc or a placebo. CD4+ and CD8+ cell maturation phenotypes, expression of PD-1 and CCR5, and activation indices were measured at weeks 0, 4, 12, 24, and 48...
2017: Pathogens & Immunity
https://www.readbyqxmd.com/read/28705187/analysis-of-home-based-rehabilitation-in-patients-with-motor-impairment-in-primary-care-a-prospective-observational-study
#4
Francisco Antonio Vega-Ramírez, Remedios López-Liria, Genoveva Granados-Gámez, Jose Manuel Aguilar-Parra, David Padilla-Góngora
BACKGROUND: The purpose of health and social policies is to encourage older people more longevity, remain free of disability and experience quality of life while living in their homes. The aim of this study was to describe the characteristics of 473 patients diagnosed with motor impairment in primary care, the objectives of home-based rehabilitation and its functional impact. METHODS: This prospective observational study was conducted in the Almería Health District...
July 14, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28697038/sleep-quality-and-its-association-with-postural-stability-and-fear-of-falling-among-spanish-postmenopausal-women
#5
Fidel Hita-Contreras, Noelia Zagalaz-Anula, Antonio Martínez-Amat, David Cruz-Díaz, Indalecio Sánchez-Montesinos, Agustín Aibar-Almazán, Rafael Lomas-Vega
OBJECTIVE: To analyze the association of sleep quality with postural balance, as measured with objective stabilometric parameters, and fear of falling (FoF), among Spanish postmenopausal women. METHODS: In all, 250 women (60 ± 8 years) took part in this cross-sectional study. Sociodemographic and anthropometric data were collected, as well as information concerning history of falls and FoF. Anxiety and depression were assessed using the Hospital Anxiety and Depression Scale, and the Pittsburgh Sleep Quality Index was used to analyze sleep quality...
July 10, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28665414/etx2514-is-a-broad-spectrum-%C3%AE-lactamase-inhibitor-for-the-treatment-of-drug-resistant-gram-negative-bacteria-including-acinetobacter-baumannii
#6
Thomas F Durand-Réville, Satenig Guler, Janelle Comita-Prevoir, Brendan Chen, Neil Bifulco, Hoan Huynh, Sushmita Lahiri, Adam B Shapiro, Sarah M McLeod, Nicole M Carter, Samir H Moussa, Camilo Velez-Vega, Nelson B Olivier, Robert McLaughlin, Ning Gao, Jason Thresher, Tiffany Palmer, Beth Andrews, Robert A Giacobbe, Joseph V Newman, David E Ehmann, Boudewijn de Jonge, John O'Donnell, John P Mueller, Rubén A Tommasi, Alita A Miller
Multidrug-resistant (MDR) bacterial infections are a serious threat to public health. Among the most alarming resistance trends is the rapid rise in the number and diversity of β-lactamases, enzymes that inactivate β-lactams, a class of antibiotics that has been a therapeutic mainstay for decades. Although several new β-lactamase inhibitors have been approved or are in clinical trials, their spectra of activity do not address MDR pathogens such as Acinetobacter baumannii. This report describes the rational design and characterization of expanded-spectrum serine β-lactamase inhibitors that potently inhibit clinically relevant class A, C and D β-lactamases and penicillin-binding proteins, resulting in intrinsic antibacterial activity against Enterobacteriaceae and restoration of β-lactam activity in a broad range of MDR Gram-negative pathogens...
June 30, 2017: Nature Microbiology
https://www.readbyqxmd.com/read/28652112/multinational-retrospective-case-control-study-of-risk-factors-for-the-development-of-late-invasive-pulmonary-aspergillosis-following-kidney-transplantation
#7
Francisco López-Medrano, Mario Fernández-Ruiz, José Tiago Silva, Peggy L Carver, Christian van Delden, Esperanza Merino, María José Pérez-Saez, Milagros Montero, Julien Coussement, Milene de Abreu Mazzolin, Carlos Cervera, Lidia Santos, Nuria Sabé, Anne Scemla, Elisa Cordero, Leónidas Cruzado-Vega, Paloma Leticia Martín-Moreno, Óscar Len, Eddison Rudas, Alfredo Ponce de León, Mariano Arriola, Ricardo Lauzurica, Miruna D David, Claudia González-Rico, Fernando Henríquez-Palop, Jesús Fortún, Marcio Nucci, Oriol Manuel, José Ramón Paño-Pardo, Miguel Montejo, Antonio Vena, Beatriz Sánchez-Sobrino, Auxiliadora Mazuecos, Julio Pascual, Juan Pablo Horcajada, Thanh Lecompte, Asunción Moreno, Jordi Carratalà, Marino Blanes, Domingo Hernández, Erick Alejandro Hernández-Méndez, María Carmen Fariñas, Manuel Perelló-Carrascosa, Patricia Muñoz, Amado Andrés, José María Aguado
OBJECTIVES: To assess the risk factors for the development of late-onset invasive pulmonary aspergillosis (IPA) after kidney transplantation (KT). METHODS: We performed a multinational case-control study that retrospectively recruited 112 KT recipients diagnosed with IPA between 2000 and 2013. Controls were matched (1:1 ratio) by center and date of transplantation. Immunosuppression-related events (IREs) included the occurrence of non-ventilator-associated pneumonia, tuberculosis, cytomegalovirus disease and/or de novo malignancy...
June 23, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28625352/rna-seq-and-metabolic-flux-analysis-of-tetraselmis-sp-m8-during-nitrogen-starvation-reveals-a-two-stage-lipid-accumulation-mechanism
#8
David K Y Lim, Holger Schuhmann, Skye R Thomas-Hall, Kenneth C K Chan, Taylor J Wass, Felipe Aguilera, T Catalina Adarme-Vega, Cristiana G O Dal'Molin, Glen J Thorpe, Jacqueline Batley, David Edwards, Peer M Schenk
To map out key lipid-related pathways that lead to rapid triacylglyceride accumulation in oleaginous microalgae, RNA-Seq was performed with Tetraselmis sp. M8 at 24h after exhaustion of exogenous nitrogen to reveal molecular changes during early stationary phase. Further gene expression profiling by quantitative real-time PCR at 16-72h revealed a distinct shift in expression of the fatty acid/triacylglyceride biosynthesis and β-oxidation pathways, when cells transitioned from log-phase into early-stationary and stationary phase...
June 6, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28602767/an-easily-transfectable-cell-line-that-produces-an-infectious-reporter-virus-for-routine-and-robust-quantitation-of-kaposi-s-sarcoma-associated-herpesvirus-reactivation
#9
Jennifer L DeCotiis, Noelle C Ortiz, Brian A Vega, David M Lukac
Reactivation of Kaposi's sarcoma-associated herpesvirus (KHSV; also known as Human herpesvirus (HHV)-8) from latency is associated with progression to disease. The primary experimental models for studying KSHV reactivation are B lymphocyte cell lines derived from patients with primary effusion lymphoma (PEL). PEL models have remained essential tools for understanding molecular details of latency and reactivation, yet they have shortcomings. In particular, PEL cells are difficult to transfect with plasmid DNA, which limits their routine use in studies that require introduction of exogenous DNA...
September 2017: Journal of Virological Methods
https://www.readbyqxmd.com/read/28589934/dna-vaccination-protects-mice-against-zika-virus-induced-damage-to-the-testes
#10
Bryan D Griffin, Kar Muthumani, Bryce M Warner, Anna Majer, Mable Hagan, Jonathan Audet, Derek R Stein, Charlene Ranadheera, Trina Racine, Marc-Antoine De La Vega, Jocelyne Piret, Stephanie Kucas, Kaylie N Tran, Kathy L Frost, Christine De Graff, Geoff Soule, Leanne Scharikow, Jennifer Scott, Gordon McTavish, Valerie Smid, Young K Park, Joel N Maslow, Niranjan Y Sardesai, J Joseph Kim, Xiao-Jian Yao, Alexander Bello, Robbin Lindsay, Guy Boivin, Stephanie A Booth, Darwyn Kobasa, Carissa Embury-Hyatt, David Safronetz, David B Weiner, Gary P Kobinger
Zika virus (ZIKV) is an emerging pathogen causally associated with serious sequelae in fetuses, inducing fetal microcephaly and other neurodevelopment defects. ZIKV is primarily transmitted by mosquitoes, but can persist in human semen and sperm, and sexual transmission has been documented. Moreover, exposure of type-I interferon knockout mice to ZIKV results in severe damage to the testes, epididymis and sperm. Candidate ZIKV vaccines have shown protective efficacy in preclinical studies carried out in animal models, and several vaccines have entered clinical trials...
June 7, 2017: Nature Communications
https://www.readbyqxmd.com/read/28555362/the-incidence-of-drug-and-herbal-and-dietary-supplement-induced-liver-injury-preliminary-findings-from-gastroenterologist-based-surveillance-in-the-population-of-the-state-of-delaware
#11
Maricruz Vega, Manisha Verma, David Beswick, Stephanie Bey, Jared Hossack, Nathan Merriman, Ashish Shah, Victor Navarro
BACKGROUND AND AIM: The population-based incidence rate of drug-induced liver injury (DILI) in the USA is not known. The Drug-Induced Liver Injury Network (DILIN) accrues cases of hepatotoxicity due to medications and herbal and dietary supplements (HDS) from limited geographical areas. The current analysis was an ancillary study of DILIN aimed at determining the annual incidence of DILI in the USA on a population basis, through surveillance in the state of Delaware. METHODS: At the outset of the study, there were 41 gastroenterologists in the state of Delaware and all agreed to participate in surveillance for DILI, which comprised active reporting of suspected cases to the DILIN...
May 29, 2017: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
https://www.readbyqxmd.com/read/28555172/multimodal-laser-based-angioscopy-for-structural-chemical-and-biological-imaging-of-atherosclerosis
#12
Luis E Savastano, Quan Zhou, Arlene Smith, Karla Vega, Carlos Murga-Zamalloa, David Gordon, Jon McHugh, Lili Zhao, Michael Wang, Aditya Pandey, B Gregory Thompson, Jie Xu, Jifeng Zhang, Y Eugene Chen, Eric J Seibel, Thomas D Wang
The complex nature of atherosclerosis demands high-resolution approaches to identify subtle thrombogenic lesions and define the risk of plaque rupture. Here, we report the proof-of-concept use of a multimodal scanning fiber endoscope (SFE) consisting of a single optical fiber scanned by a piezoelectric drive that illuminates tissue with red, blue, and green laser beams, and digitally reconstructs images at 30 Hz with high resolution and large fields-of-view. By combining laser-induced reflectance and fluorescence emission of intrinsic fluorescent constituents in arterial tissues, the SFE allowed us to co-generate endoscopic videos with a label-free biochemical map to derive a morphological and spectral classifier capable of discriminating early, intermediate, advanced, and complicated atherosclerotic plaques...
2017: Nature biomedical engineering
https://www.readbyqxmd.com/read/28497733/-microrna-and-inactivation-of-the-pituitary-gonadotrope-function
#13
Jérôme Lannes, David L'Hôte, Ambra Fernandez-Vega, Ghislaine Garrel, Jean-Noël Laverrière, Joëlle Cohen-Tannoudji, Bruno Quérat
No abstract text is available yet for this article.
April 2017: Médecine Sciences: M/S
https://www.readbyqxmd.com/read/28497027/data-based-radiation-oncology-design-of-clinical-trials-in-the-toxicity-biomarkers-era
#14
REVIEW
David Azria, Ariane Lapierre, Sophie Gourgou, Dirk De Ruysscher, Jacques Colinge, Philippe Lambin, Muriel Brengues, Tim Ward, Søren M Bentzen, Hubert Thierens, Tiziana Rancati, Christopher J Talbot, Ana Vega, Sarah L Kerns, Christian Nicolaj Andreassen, Jenny Chang-Claude, Catharine M L West, Corey M Gill, Barry S Rosenstein
The ability to stratify patients using a set of biomarkers, which predict that toxicity risk would allow for radiotherapy (RT) modulation and serve as a valuable tool for precision medicine and personalized RT. For patients presenting with tumors with a low risk of recurrence, modifying RT schedules to avoid toxicity would be clinically advantageous. Indeed, for the patient at low risk of developing radiation-associated toxicity, use of a hypofractionated protocol could be proposed leading to treatment time reduction and a cost-utility advantage...
2017: Frontiers in Oncology
https://www.readbyqxmd.com/read/28473264/aspergillus-fumigatus-empyema-in-heart-transplant-recipients
#15
Blanca De Vega Sánchez, Luis Horacio Varela Falcón, David Vielba Dueñas, Inés Sayago Silva, Luis De la Fuente Galán, Carlos Disdier Vicente
No abstract text is available yet for this article.
May 1, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28451874/characterization-of-32-microsatellite-loci-for-the-pacific-red-snapper-lutjanus-peru-through-next-generation-sequencing
#16
David A Paz-García, Adrián Munguía-Vega, Tomas Plomozo-Lugo, Amy Hudson Weaver
We developed a set of hypervariable microsatellite markers for the Pacific red snapper (Lutjanus peru), an economically important marine fish for small-scale fisheries in the west coast of Mexico. We performed shotgun genome sequencing with the 454 XL titanium chemistry and used bioinformatic tools to search for perfect microsatellite loci. We selected 66 primer pairs that were synthesized and genotyped in an ABI PRISM 3730XL DNA sequencer in 32 individuals from the Gulf of California. We estimated levels of genetic diversity, deviations from linkage and Hardy-Weinberg equilibrium, estimated the frequency of null alleles and the probability of individual identity for the new markers...
April 27, 2017: Molecular Biology Reports
https://www.readbyqxmd.com/read/28441001/-mexican-asthma-guidelines-guima-2017
#17
Désirée Larenas-Linnemann, Jorge Salas-Hernández, Juan Carlos Vázquez-García, Ignacio Ortiz-Aldana, Margarita Fernández-Vega, Blanca Estela Del Río-Navarro, María Del Carmen Cano-Salas, Jorge Agustín Luna-Pech, José Antonio Ortega-Martell, Jade Romero-Lombard, Erika Del Carmen López-Estrada, Jimena Villaverde-Rosas, José Luis Mayorga-Butrón, Mario Humberto Vargas-Becerra, Martín Bedolla-Barajas, Noel Rodríguez-Pérez, Ambrocio Aguilar-Aranda, Carlos Adrián Jiménez-González, Carlos García-Bolaños, Claudia Garrido-Galindo, David Alejandro Mendoza-Hernández, Enrique Mendoza-López, Gerardo López-Pérez, Guillermo Hideo Wakida-Kuzonoki, Héctor Hernán Ruiz-Gutiérrez, Héctor León-Molina, Héctor Martínez-De la Lanza, Héctor Stone-Aguilar, Javier Gómez-Vera, Jorge Olvera-Salinas, José Joel Oyoqui-Flores, José Luis Gálvez-Romero, José Santos Lozano-Sáenz, Juan Ignacio Salgado-Gama, Marcos Alejandro Jiménez-Chobillon, Martha Angélica García-Avilés, Martha Patricia Guinto-Balanzar, Miguel Alejandro Medina-Ávalos, Robert Camargo-Angeles, Rogelio García-Torrentera, Saraí Toral-Freyre, Gabriel Montes-Narváez, Héctor Solorio-Gómez, Juan Rosas-Peña, Sergio Jesús Romero-Tapia, Adela Reyes-Herrera, Francisco Cuevas-Schacht, Joaquín Esquer-Flores, José Antonio Sacre-Hazouri, Lorenzo Compean-Martínez, Pablo Julián Medina-Sánchez, Sergio Garza-Salinas, Carlos Báez-Loyola, Iraís Romero-Alvarado, José Luis Miguel-Reyes, Laura Elizabeth Huerta-Espinosa, Manuel Ángel Correa-Flores, Ricardo Castro-Martínez
BACKGROUND: The need for a national guideline, with a broad basis among specialists and primary care physicians was felt in Mexico, to try unifying asthma management. As several high-quality asthma guidelines exist worldwide, it was decided to select the best three for transculturation. METHODS: Following the internationally recommended methodology for guideline transculturation, ADAPTE, a literature search for asthma guidelines, published 1-1-2007 through 31-12-2015 was conducted...
2017: Revista Alergia Mexico: Organo Oficial de la Sociedad Mexicana de Alergia e Inmunología, A.C
https://www.readbyqxmd.com/read/28399287/response-to-resolving-confusion-in-the-use-of-concepts-and-terminology-in-intrapuparial-development-studies-of-cyclorrhaphous-diptera-by-martin-vega-et-al-2016
#18
https://www.readbyqxmd.com/read/28369458/the-healthy-brain-network-serial-scanning-initiative-a-resource-for-evaluating-inter-individual-differences-and-their-reliabilities-across-scan-conditions-and-sessions
#19
David O'Connor, Natan Vega Potler, Meagan Kovacs, Ting Xu, Lei Ai, John Pellman, Tamara Vanderwal, Lucas C Parra, Samantha Cohen, Satrajit Ghosh, Jasmine Escalera, Natalie Grant-Villegas, Yael Osman, Anastasia Bui, R Cameron Craddock, Michael P Milham
Background: Although typically measured during the resting state, a growing literature is illustrating the ability to map intrinsic connectivity with functional MRI during task and naturalistic viewing conditions. These paradigms are drawing excitement due to their greater tolerability in clinical and developing populations and because they enable a wider range of analyses (e.g., inter-subject correlations). To be clinically useful, the test-retest reliability of connectivity measured during these paradigms needs to be established...
February 1, 2017: GigaScience
https://www.readbyqxmd.com/read/28366374/sequential-intrastromal-corneal-ring-segment-and-monofocal-intraocular-lens-implantation-for-keratoconus-and-cataract-long-term-follow-up
#20
José F Alfonso, Carlos Lisa, Luis Fernández-Vega Cueto, Arancha Poo-López, David Madrid-Costa, Luis Fernández-Vega
PURPOSE: To evaluate the efficacy, safety, predictability, and stability of sequential Ferrara intrastromal corneal ring segment (ICRS) and intraocular lens (IOL) implantation in patients with keratoconus and cataract. SETTING: Fernández-Vega Ophthalmological Institute, Oviedo, Spain. DESIGN: Retrospective case series. METHODS: This study comprised patients with keratoconus and cataract who had ICRS implantation followed 6 months later by IOL implantation...
February 2017: Journal of Cataract and Refractive Surgery
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