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Duc Nguyen

Lan N Vuong, Vinh Q Dang, Tuong M Ho, Bao G Huynh, Duc T Ha, Toan D Pham, Linh K Nguyen, Robert J Norman, Ben W Mol
BACKGROUND: Among women who are undergoing in vitro fertilization (IVF), the transfer of frozen embryos has been shown to result in a higher rate of live birth than the transfer of fresh embryos in those with infertility associated with the polycystic ovary syndrome. It is not known whether frozen-embryo transfer results in similar benefit in women with infertility that is not associated with the polycystic ovary syndrome. METHODS: We randomly assigned 782 infertile women without the polycystic ovary syndrome who were undergoing a first or second IVF cycle to receive either a frozen embryo or a fresh embryo on day 3...
January 11, 2018: New England Journal of Medicine
Canh Chuong Nguyen, Minh Duc Duong, Nguyen Duy Anh, Thi Vui Le, Pham Sy Cuong Le, Doan Thi Thuy Duong, Thi Thu Ha Bui
Our study aimed to identify the knowledge, attitude and factors associated with uptake of amniocentesis test amongst pregnant women of advanced maternal age (35+ years old). A cross-sectional survey was performed on 481 participants in 2016. Women with higher educational attainment, higher income level, having a baby with congenital defects, and women with better knowledge and/or attitude about amniocentesis test were more likely to accept the test. Our study suggested the importance of counselling for women and given more time for them to absorb information before they make their decision to uptake the amniocentesis test...
January 10, 2018: Health Care for Women International
Tuan Hai Nguyen, Tho Duc Pham, Naomi Higa, Hanako Iwashita, Taichiro Takemura, Makoto Ohnishi, Kouichi Morita, Tetsu Yamashiro
Vibrio cholerae O1 El Tor, the pathogen responsible for the current cholera pandemic became pathogenic by acquiring virulent factors including Vibrio seventh pandemic islands (VSP)-I and -II. Diversity of VSP-II are well recognized, however, studies addressing attachment sequence left (attL) sequences of VSP-II are few. In this report, a wide variety of V. cholerae strains were analyzed for the structure and distribution of VSP-II in relation to their attachment sequences. Of 188 V. cholerae strains analyzed, 81% (153/188) strains carried VSP-II, of those, typical VSP-II, and a short variant was found in 36% (55/153), and 63% (96/153), respectively...
January 8, 2018: Microbiology and Immunology
Duong Le Quyen, Nguyen Thanh Le, Cao Thi Van Anh, Nguyen Binh Nguyen, Dong Van Hoang, Jacqui L Montgomery, Simon C Kutcher, Nguyen Hoang Le, Nguyen Tran Hien, Duong Thi Hue Kien, Maia Rabaa, Scott L O'Neill, Cameron P Simmons, Dang Duc Anh, Katherine L Anders
Vietnam is endemic for dengue. We conducted a series of retrospective and prospective studies to characterize the epidemiology of dengue and population mobility patterns in Nha Trang city, Vietnam, with a view to rational design of trials of community-level interventions. A 10-year time series of dengue case notifications showed pronounced interannual variability, as well as spatial heterogeneity in ward-level dengue incidence (median annual coefficient of variation k = 0.47). Of 451 children aged 1-10 years enrolled in a cross-sectional serosurvey, almost one-third had evidence of a past dengue virus (DENV) infection, with older children more likely to have a multitypic response indicative of past exposure to ≥ 1 serotype...
January 8, 2018: American Journal of Tropical Medicine and Hygiene
Y Buisson, P Guyon, Y Buisson, N Osinki, C Tamames, J Leconte, M Jarry, J Robert, C Dumurgier, O Choua, M O Ahmat, K M Moussa, D Sabe, A Telniaret, A M Rabo, N Kitoko, B Allatombaye, Duong Bunn, Nguyen Hong Dao, Le Duc Huy, Hoang Le Bich Ngoc, Le Hong Tram, Tran Van Khoi, Pham Van Thuc, Pham Van Linh, K Kourouma, F T Gerald, K Kourouma, P O Saibou, G C Ngunyi, B Wombe, P Alessandroni, R Andrei, J Delmont, C Gasiglia, V V Haï, M Heng, T Heng, C Khampho, D Mekhalfa, S Marcaggi, M Pimontipa, J-R Plotton, N A The Ngo, T Vilayphone, Tran Xuan Duong, Nguyen Lam Hoa, J-F Pays, P Buchy, C Goujon, O Bouchaud, P-H Consigny, L de Gentile, E D'Ortenzio, Ph Gautret, F Sorge, C Strady, E Pichard, C Haddar, E Bégaud, Mook Yun Yuh, Eng Lim Law, Y Germani, O Bouchaud, S Houze, J Chandenier, J Jannin, P Solano, I Quick, P Debre, P Guyon, A Ensaf, P Bourée, B Fabre-Teste, M El Mouden, G Soula
No abstract text is available yet for this article.
December 2017: Bulletin de la Société de Pathologie Exotique
Dinh-Duc Nguyen, Suhwan Chang
MicroRNAs (miRs, miRNAs) are regulatory small noncoding RNAs, with their roles already confirmed to be important for post-transcriptional regulation of gene expression affecting cell physiology and disease development. Upregulation of a cancer-causing miRNA, known as oncogenic miRNA, has been found in many types of cancers and, therefore, represents a potential new class of targets for therapeutic inhibition. Several strategies have been developed in recent years to inhibit oncogenic miRNAs. Among them is a direct approach that targets mature oncogenic miRNA with an antisense sequence known as antimiR, which could be an oligonucleotide or miRNA sponge...
December 27, 2017: International Journal of Molecular Sciences
Lauren B Carrington, Bich Chau Nguyen Tran, Nhat Thanh Hoang Le, Tai Thi Hue Luong, Truong Thanh Nguyen, Phong Thanh Nguyen, Chau Van Vinh Nguyen, Huong Thi Cam Nguyen, Trung Tuan Vu, Long Thi Vo, Dui Thi Le, Nhu Tuyet Vu, Giang Thi Nguyen, Hung Quoc Luu, Anh Duc Dang, Timothy P Hurst, Scott L O'Neill, Vi Thuy Tran, Duong Thi Hue Kien, Nguyet Minh Nguyen, Marcel Wolbers, Bridget Wills, Cameron P Simmons
The wMel strain of Wolbachia can reduce the permissiveness of Aedes aegypti mosquitoes to disseminated arboviral infections. Here, we report that wMel-infected Ae. aegypti (Ho Chi Minh City background), when directly blood-fed on 141 viremic dengue patients, have lower dengue virus (DENV) transmission potential and have a longer extrinsic incubation period than their wild-type counterparts. The wMel-infected mosquitoes that are field-reared have even greater relative resistance to DENV infection when fed on patient-derived viremic blood meals...
December 26, 2017: Proceedings of the National Academy of Sciences of the United States of America
Nguyen-Thach Tung, Cao-Son Tran, Thi-Minh-Hue Pham, Hoang-Anh Nguyen, Tran-Linh Nguyen, Sang-Cheol Chi, Dinh-Duc Nguyen, Thi-Bich-Huong Bui
The study first aimed to apply a design of experiment (DoE) approach to investigate the influences of excipients on the properties of liquid self-microemulsifying drug delivery system (SMEDDS) and SMEDDS loaded in the pellet (pellet-SMEDDS) containing l-tetrahydropalmatine (l-THP). Another aim of the study was to compare the bioavailability of l-THP suspension, liquid SMEDDS and pellet-SMEDDS in the rabbit model. By using Central Composite Face design (CCF), the optimum ratio of Capryol 90, and Smix `(Cremophor RH 40: Transcutol HP) in the formulation of SMEDDS was determined...
December 12, 2017: International Journal of Pharmaceutics
Truong Quang Nguyen, Anh VAN Pham, Thomas Ziegler, Hanh Thi Ngo, Minh Duc LE
We describe a new species of Cyrtodactylus on the basis of four specimens collected from the limestone karst forest of Phu Yen District, Son La Province, Vietnam. Cyrtodactylus sonlaensis sp. nov. is distinguished from the remaining Indochinese bent-toed geckos by a combination of the following characters: maximum SVL of 83.2 mm; dorsal tubercles in 13-15 irregular rows; ventral scales in 34-42 rows; ventrolateral folds prominent without interspersed tubercles; enlarged femoral scales 15-17 on each thigh; femoral pores 14-15 on each thigh in males, absent in females; precloacal pores 8, in a continuous row in males, absent in females; postcloacal tubercles 2 or 3; lamellae under toe IV 18-21; dorsal head with dark brown markings, in oval and arched shapes; nuchal loop discontinuous; dorsum with five brown bands between limb insertions, third and fourth bands discontinuous; subcaudal scales distinctly enlarged...
October 30, 2017: Zootaxa
Vinh Quang Luu, Tran VAN Dung, Truong Quang Nguyen, Minh Duc LE, Thomas Ziegler
We describe a new species of the genus Cyrtodactylus from Gia Lai Province, Central Highlands of Vietnam based on morphological and molecular differences. Cyrtodactylus gialaiensis sp. nov. is differentiated from other congeners by a unique combination of the following characters: Size small, maximum known SVL reaching 62.8 mm; dorsal pattern consisting of six or seven dark transverse bands between limb insertions; intersupranasals two or three; dorsal tubercles at midbody in 16-21 irregular rows, strongly developed on flanks; lateral folds poorly defined with interspersed tubercles; ventral scales between ventrolateral folds 38-45; precloacal pores nine or 10 in males, eight pitted scales in the adult female, in a continuous row; femoral pores absent; enlarged femoral scales present; postcloacal tubercles two or three; dorsal tubercles present to half of tail; subcaudal scales not enlarged...
December 5, 2017: Zootaxa
An T Nguyen, Wei-Cheng Lai, Bao Dong To, Duc Dung Nguyen, Ya-Ping Hsieh, Mario Hofmann, Hung-Chih Kan, Chia-Chen Hsu
No abstract text is available yet for this article.
December 15, 2017: ACS Applied Materials & Interfaces
Hoang M Tran, Vien T Truong, Tam M N Ngo, Quoc P V Bui, Hoang C Nguyen, Trung T Q Le, Wojciech Mazur, Eugene Chung, John M Cafardi, Khanh P N Pham, Hoang H N Duong, Thach Nguyen, Vu T Nguyen, Vinh N Pham
OBJECTIVES: We aimed to evaluate the microbiological characteristics and risk factors for mortality of infective endocarditis in two tertiary hospitals in Ho Chi Minh City, south Vietnam. MATERIALS AND METHODS: A retrospective study of 189 patients (120 men, 69 women; mean age 38 ± 18 years) with the diagnosis of probable or definite infective endocarditis (IE) according to the modified Duke Criteria admitted to The Heart Institute or Tam Duc Hospital between January 2005 and December 2014...
2017: PloS One
Bing Tian Zhao, Duc Hung Nguyen, Duc Dat Le, Jae Sue Choi, Byung Sun Min, Mi Hee Woo
Since PTP1B enzyme was discovered in 1988, it has captured the research community's attention. This landmark discovery has stimulated numerous research studies on a variety of human diseases, including cancer, inflammation, and diabetes. Tremendous progress has been made in finding PTP1B inhibitors and exploring PTP1B regulatory mechanisms. This review investigates for the natural PTP1B inhibitors, and focuses on the common characteristics of the discovered structures and structure-activity relationships. To facilitate understanding, all the natural compounds are here divided into five different classes (fatty acids, phenolics, terpenoids, steroids, and alkaloids), according to their skeletons...
December 6, 2017: Archives of Pharmacal Research
Anh Thi Kim Le, Hanh Thi Duc Tran, Tuan Kim Duong, Chuong Canh Nguyen, Ha Thi Thu Bui
We conducted this study to analyse factors related to reproductive tract infections (RTIs) among female migrant workers (FMWs) in four industrial zones across four regions in Vietnam. A analytical cross-sectional study was implemented with FMWs aged between 18-49 years old in four industrial zones in Hanoi, Da Nang, Ho Chi Minh city (HCM) and Binh Duong, Vietnam. Stratified sampling was used to select about 6400 married and unmarried FMWs. Cases were identified through self-reporting of female migrants concerning RTIs symtoms experienced in the 1 year prior to the study...
December 6, 2017: Health Care for Women International
Nguyen Thi Hoang Anh, Khieu Thi Tam, Nguyen Van Tuan, Dao Duc Thien, Tran Duc Quan, Nguyen Thanh Tam, Nguyen Chi Bao, Thi Thao Do, Nguyen Thi Nga, Trinh Thi Thuy, Tran Van Sung, Domenico V Delfino
This study describes the chemical constituents of Oldenlandia pinifolia (Wall. Ex G. Don) Kuntze (synonym Hedyotis pinifolia Wall. Ex G. Don) and discusses their anti-proliferative activities. Thirteen compounds were isolated from the n-hexane, ethyl acetate and n-butanol extracts of whole plants O. pinifolia by chromatography method. Their structures were elucidated using MS and NMR analysis and compared with reported data. They are three anthraquinones, a carotenoid, two triterpenes, four iridoid glycosides and three flavonoid glycosides...
December 6, 2017: Natural Product Research
Thi Minh Tam Ta, Kerem Böge, Tien Duc Cao, Georg Schomerus, Tat Dinh Nguyen, Michael Dettling, Aditya Mungee, Lara Kim Martensen, Albert Diefenbacher, Matthias C Angermeyere, Eric Hahn
OBJECTIVES: Mental health associated stigmatization remains problematic in low and middle-income countries, thus preventing patients from adequate access to psychiatric care. Public attitudes towards psychiatrists have not been examined in many countries, especially not in Vietnam where merely one psychiatrist per 300.000 population is available. The study aims to explore attitudes towards psychiatrists in the Hanoi municipality and to identify socio-demographical factors that influence these attitudes...
November 28, 2017: Asian Journal of Psychiatry
Duy Duc Nguyen, Nykola C Jones, Søren Vrønning Hoffmann, Jens Spanget-Larsen
p-Terphenyl is used as a component in a variety of optical devices. In this investigation, the electronic transitions of p-terphenyl are investigated by synchrotron radiation linear dichroism (SRLD) spectroscopy in the range 30000 - 58000 cm-1 (330 - 170 nm) on molecular samples aligned in stretched polyethylene, thereby extending the region investigated by polarization spectroscopy into the vacuum UV. The resulting partial absorbance curves reveal that the vacuum UV band system with a maximum at 55000 cm-1 (180 nm) is predominantly short axis-polarized...
December 5, 2017: Journal of Physical Chemistry. A
Robert Townsend Cole, Jonathan Gandhi, Robert A Bray, Howard M Gebel, Michael Yin, Nikolaz Shekiladze, An Young, Aubrey Grant, Ian Mahoney, S Raja Laskar, Divya Gupta, Kunal Bhatt, Wendy Book, Andrew Smith, Duc Nguyen, J David Vega, Alanna A Morris
BACKGROUND: Despite improvements in outcomes after heart transplantation, black recipients have worse survival compared with non-black recipients. The source of such disparate outcomes remains largely unknown. We hypothesize that a propensity to generate de-novo donor-specific antibodies (dnDSA) and subsequent antibody-mediated rejection (AMR) may account for racial differences in sub-optimal outcomes after heart transplant. In this study we aimed to determine the role of dnDSA and AMR in racial disparities in post-transplant outcomes...
November 4, 2017: Journal of Heart and Lung Transplantation
Hyo Sang Jang, Martin Pearce, Edmond F O'Donnell, Bach Duc Nguyen, Lisa Truong, Monica J Mueller, William H Bisson, Nancy I Kerkvliet, Robert L Tanguay, Siva Kumar Kolluri
We previously reported that raloxifene, an estrogen receptor modulator, is also a ligand for the aryl hydrocarbon receptor (AhR). Raloxifene induces apoptosis in estrogen receptor-negative human cancer cells through the AhR. We performed structure-activity studies with seven raloxifene analogs to better understand the structural requirements of raloxifene for induction of AhR-mediated transcriptional activity and apoptosis. We identified Y134 as a raloxifene analog that activates AhR-mediated transcriptional activity and induces apoptosis in MDA-MB-231 human triple negative breast cancer cells...
December 1, 2017: Biology
Sam Thi Nguyen, Yasuhiro Fukuda, Duc Tan Nguyen, Ha Thanh Dao, Duc Quyet LE, Khanh Linh Bui, Chika Tada, Yutaka Nakai
This study was carried out to determine the prevalence, genotypes/assemblages and possible risk factors associated with Giardia duodenalis infection in dogs in central Vietnam. A total of 209 dog fecal samples, randomly collected from private owned dogs (n=105) and dogs from stores (n=104), were examined for Giardia cysts by microscopy. Positive samples were genotyped by PCR-sequence analysis of β-giardin and triosephosphate isomerase genes markers. Risk factors were studied using a structured questionnaire and collected data were analyzed by univariate and multivariate logistic regression analyses...
November 29, 2017: Journal of Veterinary Medical Science
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