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https://www.readbyqxmd.com/read/27893861/attitudes-towards-intimate-partner-violence-against-women-among-women-and-men-in-39-low-and-middle-income-countries
#1
Thach Duc Tran, Hau Nguyen, Jane Fisher
BACKGROUND: Violence against women perpetrated by an intimate partner (IPV) is prevalent in low- and middle-income countries (LAMIC). The aim was to describe the attitudes of women and men towards perpetration of physical violence to women by an intimate partner, in a large group of low- and middle-income countries. METHODS AND FINDINGS: We used data from Round Four of the UNICEF Multiple Indicator Cluster Surveys. Attitudes towards IPV against women were assessed by a study-specific scale asking if 'wife beating' is justified in any of five circumstances...
2016: PloS One
https://www.readbyqxmd.com/read/27889684/human-milk-oligosaccharide-effects-on-intestinal-function-and-inflammation-after-preterm-birth-in-pigs
#2
Stine O Rasmussen, Lena Martin, Mette V Østergaard, Silvia Rudloff, Michael Roggenbuck, Duc Ninh Nguyen, Per T Sangild, Stine B Bering
: Human milk oligosaccharides (HMOs) may mediate prebiotic and anti-inflammatory effects in newborns. This is particularly important for preterm infants who are highly susceptible to intestinal dysfunction and necrotizing enterocolitis (NEC). We hypothesized that HMO supplementation of infant formula (IF) improves intestinal function, bacterial colonization and NEC resistance immediately after preterm birth, as tested in a preterm pig model. Mixtures of HMOs were investigated in intestinal epithelial cells and in preterm pigs (n=112) fed IF supplemented without (CON) or with a mixture of four HMOs (4-HMO) or >25 HMOs (25-HMO, 5-10 g/L given for 5 or 11 days)...
November 4, 2016: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/27887578/evaluation-of-an-international-educational-programme-for-health-care-professionals-on-best-practice-in-the-management-of-a-perinatal-death-improving-perinatal-mortality-review-and-outcomes-via-education-improve
#3
Paul A Gardiner, Alison L Kent, Viviana Rodriguez, Aleena M Wojcieszek, David Ellwood, Adrienne Gordon, Patricia A Wilson, Diana M Bond, Adrian Charles, Susan Arbuckle, Glenn J Gardener, Jeremy J Oats, Jan Jaap Erwich, Fleurisca J Korteweg, T H Nguyen Duc, Susannah Hopkins Leisher, Kamal Kishore, Robert M Silver, Alexander E Heazell, Claire Storey, Vicki Flenady
BACKGROUND: Stillbirths and neonatal deaths are devastating events for both parents and clinicians and are global public health concerns. Careful clinical management after these deaths is required, including appropriate investigation and assessment to determine cause (s) to prevent future losses, and to improve bereavement care for families. An educational programme for health care professionals working in maternal and child health has been designed to address these needs according to the Perinatal Society of Australia and New Zealand Guideline for Perinatal Mortality: IMproving Perinatal mortality Review and Outcomes Via Education (IMPROVE)...
November 25, 2016: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/27878546/investigation-of-antibiotics-in-health-care-wastewater-in-ho-chi-minh-city-vietnam
#4
Thi-Dieu-Hien Vo, Xuan-Thanh Bui, Ngoc-Dan-Thanh Cao, Vinh-Phuc Luu, Thanh-Tin Nguyen, Bao-Trong Dang, Minh-Quan Thai, Dinh-Duc Nguyen, Thanh-Son Nguyen, Quoc-Tuc Dinh, Thanh-Son Dao
Hospital wastewater contains huge amounts of hazardous pollutants which are being discharged daily to environment with or without treatment. Antibiotics were among the important group of pharmaceuticals considered as a potential source of health risk for human and other living creatures. Although the investigations about the existence of antibiotics in hospital wastewater have gained concern for researchers in many countries, there is only one research conducted in Hanoi-Vietnam. Hence, in this study, investigations have been done to fulfill the requirement of real situation in Vietnam by accomplishing survey for 39 health care facilities in Ho Chi Minh City...
December 0: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/27877174/dna-methyltransferase-inhibitor-promotes-human-cd4-cd25-h-foxp3-regulatory-t-lymphocyte-induction-under-suboptimal-tcr-stimulation
#5
Chun-Hao Lu, Cheng-Jang Wu, Cheng-Chi Chan, Duc T Nguyen, Kuo-Ray Lin, Syh-Jae Lin, Li-Chen Chen, Jeffrey Jong-Yong Yen, Ming-Ling Kuo
The "master transcription factor" FOXP3 regulates the differentiation, homeostasis, and suppressor function of CD4(+) regulatory T (Treg) cells, which are critical in maintaining immune tolerance. Epigenetic regulation of FOXP3 expression has been demonstrated to be important to Treg cell development, but the induction of human Treg cells through epigenetic modification has not been clearly described. We report that the combination of the DNA methyltransferase inhibitor 5-azacytidine (5-Aza) and suboptimal T cell receptor (TCR) stimulation promoted CD4(+)CD25(h)FOXP3(+) T cell induction from human CD4(+)CD25(-) T cells...
2016: Frontiers in Immunology
https://www.readbyqxmd.com/read/27872945/ascaris-lumbricoides-egg-die-off-in-an-experimental-excreta-storage-system-and-public-health-implication-in-vietnam
#6
Tu Vu-Van, Phuc Pham-Duc, Mirko S Winkler, Christian Zurbrügg, Jakob Zinsstag, Huong Le Thi Thanh, Tran Huu Bich, Hung Nguyen-Viet
OBJECTIVES: We studied the influence of different additive materials (lime, and rice husk) and aeration conditions on Ascaris lumbricoides egg die-off in 24 vaults of an experimental excreta storage unit. METHODS: Excreta samples were collected once every two weeks over a 181-day period. Temperature, pH, and moisture content were recorded. A. lumbricoides eggs were quantitatively analyzed by the Romanenko method, which identified and counted live and dead eggs. RESULTS: From the first sampling (0 storage day) to the final sampling (181 storage days) the average percentage of viable A...
November 22, 2016: International Journal of Public Health
https://www.readbyqxmd.com/read/27872490/use-of-zebrafish-larvae-as-a-multi-endpoint-platform-to-characterize-the-toxicity-profile-of-silica-nanoparticles
#7
Duc-Hung Pham, Bert De Roo, Xuan-Bac Nguyen, Mattias Vervaele, Angela Kecskés, Annelii Ny, Daniëlle Copmans, Hanne Vriens, Jean-Pierre Locquet, Peter Hoet, Peter A M de Witte
Nanomaterials are being extensively produced and applied in society. Human and environmental exposures are, therefore, inevitable and so increased attention is being given to nanotoxicity. While silica nanoparticles (NP) are one of the top five nanomaterials found in consumer and biomedical products, their toxicity profile is poorly characterized. In this study, we investigated the toxicity of silica nanoparticles with diameters 20, 50 and 80 nm using an in vivo zebrafish platform that analyzes multiple endpoints related to developmental, cardio-, hepato-, and neurotoxicity...
November 22, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27872070/estimation-of-the-in-vivo-minimum-inhibitory-concentration-of-cipargamin-in-uncomplicated-plasmodium-falciparum-malaria
#8
Hien Tinh Tran, Nicholas J White, Thuy-Nhien Thanh Nguyen, Hoa Thi Nhu, Thuan Duc Phung, Joel Tarning, François Nosten, Baldur Magnusson, Jay Prakash Jain, Kamal Hamed
The minimum inhibitory concentration (MIC) of an antimalarial drug for a particular infection is the drug level associated with a net parasite multiplication rate of one per asexual cycle. To ensure cure of malaria the MIC must be exceeded until all parasites have been eliminated. The development of highly sensitive and accurate polymerase chain reaction quantitation of low-density malaria parasitemia enables prospective pharmacokinetic-pharmacodynamic (PK-PD) characterization of antimalarial drug effects, and now allows identification of the in-vivo MIC...
November 21, 2016: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/27861139/in-vitro-antioxidant-and-anti-inflammatory-activities-of-isolated-compounds-of-ethanol-extract-from-sanchezia-speciosa-leonard-s-leaves
#9
Tung Bui Thanh, Loi Vu Duc, Hai Nguyen Thanh, Vung Nguyen Tien
BACKGROUND: Sanchezia speciosa has been used in traditional medicine for gastritis treatment in Vietnam. Some phytochemical study showed that S. speciosa contains high amounts of flavonoids and cardiac glycoside compounds. In the present study, we isolated four compounds from the ethanol extract of the S. speciosa leaf, and we evaluated the in vitro antioxidant and anti-inflammatory effect of the isolated compound from the ethanol extract of the S. speciosa leaf. METHODS: The leaf of S...
November 18, 2016: Journal of Basic and Clinical Physiology and Pharmacology
https://www.readbyqxmd.com/read/27855667/molecular-evolution-of-type-2-porcine-reproductive-and-respiratory-syndrome-viruses-circulating-in-vietnam-from-2007-to-2015
#10
Hai Quynh Do, Dinh Thau Trinh, Thi Lan Nguyen, Thi Thu Hang Vu, Duc Duong Than, Thi Van Lo, Minjoo Yeom, Daesub Song, SeEun Choe, Dong-Jun An, Van Phan Le
BACKGROUND: Porcine respiratory and reproductive syndrome (PRRS) virus is one of the most economically significant pathogens in the Vietnamese swine industry. ORF5, which participates in many functional processes, including virion assembly, entry of the virus into the host cell, and viral adaptation to the host immune response, has been widely used in molecular evolution and phylogeny studies. Knowing of molecular evolution of PRRSV fields strains might contribute to PRRS control in Vietnam...
November 17, 2016: BMC Veterinary Research
https://www.readbyqxmd.com/read/27851657/can-the-risks-of-cerebrospinal-fluid-leak-after-vestibular-schwannoma-surgery-be-predicted
#11
Adrien Russel, Charles P Hoffmann, Duc T Nguyen, Renaud Beurton, Cécile Parietti-Winkler
OBJECTIVE: Identifying predictive factors of cerebrospinal fluid (CSF) leak after translabyrinthine approach (TLA) for vestibular schwannoma. DESIGN: Retrospective study. SETTING: Tertiary care center. PATIENTS: All patients (n = 275) operated for a vestibular schwannoma by TLA between 2004 and 2013 were included. INTERVENTION: Vestibular schwannoma surgery by TLA. MAIN OUTCOMES AND MEASURES: The rate of postoperative CSF leak considering the age, sex, body mass index (BMI), tumor staging, and duration of surgical procedure...
November 15, 2016: Otology & Neurotology
https://www.readbyqxmd.com/read/27837223/quantitative-risk-assessment-of-human-salmonellosis-in-the-smallholder-pig-value-chains-in-urban-of-vietnam
#12
Sinh Dang-Xuan, Hung Nguyen-Viet, Fred Unger, Phuc Pham-Duc, Delia Grace, Ngan Tran-Thi, Max Barot, Ngoc Pham-Thi, Kohei Makita
OBJECTIVES: To quantify salmonellosis risk in humans through consumption of boiled pork in urban Hung Yen Province, Vietnam, using a quantitative microbial risk assessment. METHODS: We collected 302 samples along the pork value chain in Hung Yen between April 2014 and February 2015. We developed a model in @Risk, based on microbiological, market, and household surveys on cooking, cross-contamination and consumption, and conducted sensitivity analysis. RESULTS: Salmonella prevalence of pen floor swabs, slaughterhouse carcasses and cut pork were 33...
November 11, 2016: International Journal of Public Health
https://www.readbyqxmd.com/read/27837222/diarrhea-risks-by-exposure-to-livestock-waste-in-vietnam-using-quantitative-microbial-risk-assessment
#13
Thu Le-Thi, Phuc Pham-Duc, Christian Zurbrügg, Toan Luu-Quoc, Huong Nguyen-Mai, Tu Vu-Van, Hung Nguyen-Viet
OBJECTIVES: The aim of this paper was to assess the diarrhea risks caused by various pathogens among those exposed to biogas wastewater through different activities. METHODS: Application of quantitative microbial risk assessment (QMRA) of biogas wastewater was conducted in Hanam Province, Vietnam. A total of 451 representatives from households that use biogas were interviewed about their practices of handling biogas plant and reuse of biogas effluent for irrigation...
November 11, 2016: International Journal of Public Health
https://www.readbyqxmd.com/read/27830761/delayed-development-of-systemic-immunity-in-preterm-pigs-as-a-model-for-preterm-infants
#14
Duc Ninh Nguyen, Pingping Jiang, Hanne Frøkiær, Peter M H Heegaard, Thomas Thymann, Per T Sangild
Preterm neonates are highly sensitive to systemic infections in early life but little is known about systemic immune development following preterm birth. We hypothesized that preterm neonates have immature systemic immunity with distinct developmental trajectory for the first several weeks of life, relative to those born at near-term or term. Using pigs as a model, we characterized blood leukocyte subsets, antimicrobial activities and TLR-mediated cytokine production during the first weeks after preterm birth...
November 10, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27827965/arsenic-and-heavy-metal-contamination-in-soils-under-different-land-use-in-an-estuary-in-northern-vietnam
#15
Thinh Nguyen Van, Akinori Ozaki, Hoang Nguyen Tho, Anh Nguyen Duc, Yen Tran Thi, Kiyoshi Kurosawa
Heavy metal contamination of soil and sediment in estuaries warrants study because a healthy estuarine environment, including healthy soil, is important in order to achieve ecological balance and good aquaculture production. The Ba Lat estuary of the Red River is the largest estuary in northern Vietnam and is employed in various land uses. However, the heavy metal contamination of its soil has not yet been reported. The following research was conducted to clarify contamination levels, supply sources, and the effect of land use on heavy metal concentrations in the estuary...
November 5, 2016: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/27815565/exposure-assessment-of-chemical-hazards-in-pork-meat-liver-and-kidney-and-health-impact-implication-in-hung-yen-and-nghe-an-provinces-vietnam
#16
Tran Thi Tuyet-Hanh, Dang Xuan Sinh, Pham Duc Phuc, Tran Thi Ngan, Chu Van Tuat, Delia Grace, Fred Unger, Hung Nguyen-Viet
OBJECTIVES: This study assesses the risk of exposure to hazardous chemical residues in pork meat, liver, and kidney collected at wet markets in Nghe An and Hung Yen provinces and discusses health impact implication. METHODS: 514 pig feed, kidney, liver, and pork samples were pooled and qualitatively and quantitatively analyzed for tetracyclines, fluoroquinolones, sulphonamide, chloramphenicol, β-agonists, and heavy metals. We compare the results with current regulations on chemical residues and discuss health implications...
November 5, 2016: International Journal of Public Health
https://www.readbyqxmd.com/read/27814543/shipboard-and-ground-measurements-of-atmospheric-particulate-mercury-and-total-mercury-in-precipitation-over-the-yellow-sea-region
#17
Duc Luong Nguyen, Jin Young Kim, Shang-Gyoo Shim, Young Sung Ghim, Xiao-Shan Zhang
The first ever shipboard measurements for atmospheric particulate mercury (Hg(p)) over the Yellow Sea and ground measurements for atmospheric Hg(p) and total mercury (THg) in precipitation at the remote sites (Deokjeok and Chengshantou) and the urban sites (Seoul and Ningbo) surrounding the Yellow Sea were carried out during 2007-2008. The Hg(p) regional background concentration of 56.3 ± 55.6 pg m(-3) over the Yellow Sea region is much higher than the typical background concentrations of Hg(p) in terrestrial environments (<25 pg m(-3)) which implies significant impact of anthropogenic mercury emission sources from East Asia...
October 28, 2016: Environmental Pollution
https://www.readbyqxmd.com/read/27799646/seasonality-of-viral-encephalitis-and-associated-environmental-risk-factors-in-son-la-and-thai-binh-provinces-in-vietnam-from-2004-to-2013
#18
Hu Suk Lee, Hung Nguyen-Viet, Mihye Lee, Phuc Pham Duc, Delia Grace
In Vietnam, Japanese encephalitis virus accounts for 12-71% of viral encephalitis (VE) cases followed by enteroviruses and dengue virus among identified pathogens. This study is the first attempt to evaluate the seasonality of VE and associated environmental risk factors in two provinces from 2004 to 2013 using a seasonal trend-decomposition procedure based on loess regression and negative binomial regression models. We found seasonality with a peak of VE in August and June in Son La and Thai Binh, respectively...
October 31, 2016: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/27796412/coverage-of-health-insurance-among-the-near-poor-in-rural-vietnam-and-associated-factors
#19
Thanh Duc Nguyen, Andrew Wilson
OBJECTIVES: The Vietnamese government is committed to universal health care largely through social health insurance. The near-poor population is entitled to subsidized but not free insurance under this scheme, but remains under-represented compared to other groups. The aims of this research were to estimate the health insurance coverage of the near-poor in rural Vietnam and identify the individual and household factors associated with health insurance status. METHODS: Rates of health insurance coverage were estimated from district-level administrative data...
October 28, 2016: International Journal of Public Health
https://www.readbyqxmd.com/read/27782312/weighted-analysis-of-composite-endpoints-with-simultaneous-inference-for-flexible-weight-constraints
#20
Anh Nguyen Duc, Marcel Wolbers
Composite endpoints are widely used as primary endpoints of randomized controlled trials across clinical disciplines. A common critique of the conventional analysis of composite endpoints is that all disease events are weighted equally, whereas their clinical relevance may differ substantially. We address this by introducing a framework for the weighted analysis of composite endpoints and interpretable test statistics, which are applicable to both binary and time-to-event data. To cope with the difficulty of selecting an exact set of weights, we propose a method for constructing simultaneous confidence intervals and tests that asymptotically preserve the family-wise type I error in the strong sense across families of weights satisfying flexible inequality or order constraints based on the theory of χ¯2-distributions...
October 26, 2016: Statistics in Medicine
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