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Brent Keeling

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https://www.readbyqxmd.com/read/29325975/procedural-outcomes-and-long-term-survival-associated-with-lead-extraction-in-patients-with-abandoned-leads
#1
Faisal M Merchant, Thor Tejada, Adarsh Patel, Jad El-Khalil, Yaanik Desai, Brent Keeling, Omar M Lattouf, Angel R Leon, Mikhael F El-Chami
BACKGROUND: The decision to abandon or extract superfluous sterile leads is controversial. OBJECTIVE: To compare procedural outcomes and long-term survival of patients with and without abandoned leads undergoing lead extraction (LE). METHODS: Retrospective review of all patients undergoing transvenous LE at our institution from Jan. 2007 to May 2016. Patients were stratified into two groups based on the presence (Group 1) or absence (Group 2) of abandoned leads...
January 8, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29203218/the-modern-hydra-perioperative-stroke-and-cardiac-surgery
#2
EDITORIAL
Brent Keeling, Michael E Halkos
No abstract text is available yet for this article.
December 1, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29167026/safety-of-moderate-hypothermia-with-antegrade-cerebral-perfusion-in-total-aortic-arch-replacement
#3
W Brent Keeling, David H Tian, Brad G Leshnower, Satoshi Numata, G Chad Hughes, George Matalanis, Yutaka Okita, Tristan D Yan, Nicholas Kouchoukos, Edward P Chen
BACKGROUND: Total aortic arch replacement (TOTAL) is a complicated operation and has traditionally required deep hypothermic circulatory arrest. In this study, the impact of moderate hypothermic circulatory arrest (MHCA) and antegrade cerebral perfusion (ACP) for TOTAL were examined. METHODS: The ARCH International aortic database was queried and 3,265 patients undergoing TOTAL using ACP were identified. Patients were divided into groups based on lowest cooling temperature: MHCA (20° to 28°C) or deep hypothermia (DHCA) (12° to 20°C)...
November 19, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28918112/radiographic-and-clinical-comparison-of-pegged-and-keeled-glenoid-components-using-modern-cementing-techniques-midterm-results-of-a-prospective-randomized-study
#4
Christopher M Kilian, Cyrus M Press, Kevin M Smith, Daniel P O'Connor, Brent J Morris, Hussein A Elkousy, Gary M Gartsman, T Bradley Edwards
BACKGROUND: Glenoid component loosening remains a significant issue after anatomic shoulder arthroplasty. Pegged glenoid components have shown better lucency rates than keeled components in the short term; however, midterm to long-term results have not fully been determined. We previously reported early outcomes of the current randomized controlled group of patients, with higher glenoid lucency rates in those with a keeled glenoid. The purpose of this study was to evaluate the radiographic and clinical outcomes of these components at minimum 5-year follow-up...
December 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28610886/conversion-from-off-pump-coronary-artery-bypass-grafting-to-on-pump-coronary-artery-bypass-grafting
#5
Brent Keeling, Vinod Thourani, Gorav Aliawadi, Sunghee Kim, Derek Cyr, Vinay Badhwar, Jeff P Jacobs, J Matthew Brennan, James Meza, Roland Matsouaka, Michael E Halkos
BACKGROUND: Off-pump coronary artery bypass grafting (OPCAB) has been shown to be an effective strategy for surgical revascularization. The purpose of this study was to define the incidence of intraoperative conversion from OPCAB to on-pump coronary artery bypass grafting (ONCAB) and report outcomes based on the reason for conversion. METHODS: Starting in July 2007, the Society of Thoracic Surgeons database captured patients that were planned OPCAB but then were converted to ONCAB...
October 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28551049/hypothermia-and-selective-antegrade-cerebral-perfusion-is-safe-for-arch-repair-in-type-a-dissection
#6
W Brent Keeling, Bradley G Leshnower, John C Hunting, Jose Binongo, Edward P Chen
BACKGROUND: Unilateral selective antegrade cerebral perfusion with moderate hypothermic circulatory arrest has been shown to be a safe and effective method of cerebral protection during surgery for acute type A dissection. This study evaluates the impact of this cerebral protection strategy on clinical outcomes after extended aortic arch reconstruction in patients undergoing emergent repair of acute type A dissection. METHODS: A retrospective review from 2004 to 2016 at a US academic center of patients undergoing surgery for acute type A dissections using moderate hypothermic circulatory arrest and selective antegrade cerebral perfusion was performed...
September 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28460021/hypothermia-and-cerebral-protection-strategies-in-aortic-arch-surgery-a-comparative-effectiveness-analysis-from-the-sts-adult-cardiac-surgery-database
#7
Brian R Englum, Xia He, Brian C Gulack, Asvin M Ganapathi, Joseph P Mathew, J Matthew Brennan, T Brett Reece, W Brent Keeling, Bradley G Leshnower, Edward P Chen, Jeffrey P Jacobs, Vinod H Thourani, G Chad Hughes
OBJECTIVES: Hypothermic circulatory arrest is essential to aortic arch surgery, although consensus regarding optimal cerebral protection strategy remains lacking. We evaluated the current use and comparative effectiveness of hypothermia/cerebral perfusion (CP) strategies in aortic arch surgery. METHODS: Using the Society of Thoracic Surgeons Database, cases of aortic arch surgery with hypothermic circulatory arrest from 2011 to 2014 were categorized by hypothermia strategy-deep/profound (D/P; ≤20°C), low-moderate (L-M; 20...
September 1, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28110965/baby-it-s-cold-outside-does-it-need-to-be
#8
EDITORIAL
Brent Keeling, Edward P Chen
No abstract text is available yet for this article.
January 9, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27717426/the-racial-paradox-in-multiarterial-conduit-utilization-for-coronary-artery-bypass-grafting
#9
W Brent Keeling, Jose Binongo, Michael E Halkos, Bradley G Leshnower, Duc Q Nguyen, Edward P Chen, Eric L Sarin, Jeffrey S Miller, Steven Macheers, Omar M Lattouf, Robert A Guyton, Vinod H Thourani
BACKGROUND: It has been established that outcomes for black patients undergoing coronary artery bypass graft surgery (CABG) are inferior to those of their white counterparts. The purpose of this study was to determine (1) whether rates of multiarterial grafting are different among black patients and white patients, and (2) whether racial differences exist in postoperative outcomes after accounting for grafting strategy. METHODS: A retrospective review of black patients (n = 2,810) and white patients (n = 13,569) who underwent isolated, primary CABG from January 2002 to June 2014 at a US academic institution was performed...
April 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27711228/dna-mva-vaccination-of-hiv-1-infected-participants-with-viral-suppression-on-antiretroviral-therapy-followed-by-treatment-interruption-elicitation-of-immune-responses-without-control-of-re-emergent-virus
#10
Melanie Thompson, Sonya L Heath, Bentley Sweeton, Kathy Williams, Pamela Cunningham, Brandon F Keele, Sharon Sen, Brent E Palmer, Nicolas Chomont, Yongxian Xu, Rahul Basu, Michael S Hellerstein, Suefen Kwa, Harriet L Robinson
clinicaltrials.gov NCT01378156.
2016: PloS One
https://www.readbyqxmd.com/read/27666783/severity-of-preoperative-aortic-regurgitation-does-not-impact-valve-durability-of-aortic-valve-repair-following-the-david-v-valve-sparing-aortic-root-replacement
#11
W Brent Keeling, Bradley G Leshnower, Jose Binongo, Yi Lasanajak, LaRonica McPherson, Edward P Chen
BACKGROUND: The David V valve-sparing aortic root replacement (VSRR) is an established and durable method of root reconstruction for varying pathologies. However, the impact of the severity of preoperative aortic regurgitation (AR) on long-term durability remains unclear. The purpose of this research was to investigate the impact of the degree of preoperative AR on midterm durability following VSRR. METHODS: A retrospective review of the adult cardiac surgical database at a single academic center was undertaken from 2005 to 2015 for 223 adult patients who underwent VSRR...
March 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27373187/outcomes-after-surgical-pulmonary-embolectomy-for-acute-pulmonary-embolus-a-multi-institutional-study
#12
MULTICENTER STUDY
W Brent Keeling, Thor Sundt, Marzia Leacche, Yutaka Okita, Jose Binongo, Yi Lasajanak, Lishan Aklog, Omar M Lattouf
BACKGROUND: Surgical pulmonary embolectomy (SPE) has been sparingly used for the successful treatment of massive and submassive pulmonary emboli. To date, all data regarding SPE have been limited to single-center experiences. The purpose of this study was to document short-term outcomes after SPE for acute pulmonary emboli (PE) at four high-volume institutions. METHODS: A retrospective review of multiple local Society of Thoracic Surgeons databases of adults undergoing SPE from 1998 to 2014 for acute PE was performed (n = 214)...
November 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27321432/maxing-out-the-axillary-artery-for-arterial-cannulation-in-acute-type-a-dissection
#13
EDITORIAL
W Brent Keeling, Edward P Chen
No abstract text is available yet for this article.
September 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27169803/delayed-globin-synthesis-leads-to-excess-heme-and-the-macrocytic-anemia-of-diamond-blackfan-anemia-and-del-5q-myelodysplastic-syndrome
#14
Zhantao Yang, Siobán B Keel, Akiko Shimamura, Li Liu, Aaron T Gerds, Henry Y Li, Brent L Wood, Bart L Scott, Janis L Abkowitz
Diamond Blackfan anemia (DBA) and myelodysplastic syndrome (MDS) with isolated del(5q) are severe macrocytic anemias; although both are associated with impaired ribosome assembly, why the anemia occurs is not known. We cultured marrow cells from DBA (n = 3) and del(5q) MDS (n = 6) patients and determined how heme (a toxic chemical) and globin (a protein) are coordinated. We show that globin translation initiates slowly, whereas heme synthesis proceeds normally. This results in insufficient globin protein, excess heme and excess reactive oxygen species in early erythroid precursors, and CFU-E (colony-forming unit-erythroid)/proerythroblast cell death...
May 11, 2016: Science Translational Medicine
https://www.readbyqxmd.com/read/26992603/midterm-benefits-of-surgical-pulmonary-embolectomy-for-acute-pulmonary-embolus-on-right-ventricular-function
#15
William Brent Keeling, Bradley G Leshnower, Yi Lasajanak, Jose Binongo, Robert A Guyton, Michael E Halkos, Vinod H Thourani, Omar M Lattouf
OBJECTIVE: Surgical pulmonary embolectomy has been used for the successful treatment of massive and submassive pulmonary emboli. The purpose of this study is to document the short- and midterm echocardiographic follow-up of right ventricular function after surgical pulmonary embolectomy for acute pulmonary embolus. METHODS: A retrospective review of the local Society of Thoracic Surgeons database of patients who underwent surgical pulmonary embolectomy for acute pulmonary embolectomy was conducted from 1998 to 2014 at a US academic center...
September 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/26899959/injury-to-the-conduction-system-management-of-life-threatening-arrhythmias-after-penetrating-cardiac-trauma
#16
Rashi Jhunjhunwala, Christopher J Dente, William Brent Keeling, Phillip J Prest, Stacy D Dougherty, Rondi B Gelbard, William B Long, Jeffrey M Nicholas, Bryan C Morse
BACKGROUND: Life-threatening conduction abnormalities after penetrating cardiac injuries (PCIs) are rare, and rapid identification and treatment of these arrhythmias are critical to survival. This study highlights diagnosis and management strategies for conduction abnormalities after PCI. METHODS: Patients with life-threatening arrhythmias after PCI were identified at an urban, level I trauma center registry. RESULTS: Seventy-one patients survived to reach the hospital after PCI...
August 2016: American Journal of Surgery
https://www.readbyqxmd.com/read/26586359/reaching-the-full-potential-of-mep-monitoring-during-surgery-of-the-thoracoabdominal-aorta
#17
EDITORIAL
Brent Keeling, Edward P Chen
No abstract text is available yet for this article.
February 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/26522523/invited-commentary
#18
COMMENT
Brent Keeling, Michael E Halkos
No abstract text is available yet for this article.
November 2015: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/26434701/the-real-root-cause-analysis-optimizing-surgical-options-in-the-current-era
#19
EDITORIAL
Brent Keeling, Edward P Chen
No abstract text is available yet for this article.
November 2015: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/26119513/double-transcatheter-valve-in-valve-therapy-a-viable-alternative-for-high-risk-patients
#20
EDITORIAL
Brent Keeling, Edward P Chen
No abstract text is available yet for this article.
August 2015: Journal of Thoracic and Cardiovascular Surgery
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