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Seth Force

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https://www.readbyqxmd.com/read/29234814/hormone-therapy-for-the-primary-prevention-of-chronic-conditions-in-postmenopausal-women-us-preventive-services-task-force-recommendation-statement
#1
David C Grossman, Susan J Curry, Douglas K Owens, Michael J Barry, Karina W Davidson, Chyke A Doubeni, John W Epling, Alex R Kemper, Alex H Krist, Ann E Kurth, C Seth Landefeld, Carol M Mangione, Maureen G Phipps, Michael Silverstein, Melissa A Simon, Chien-Wen Tseng
Importance: Menopause occurs at a median age of 51.3 years, and the average US woman who reaches menopause is expected to live another 30 years. The prevalence and incidence of most chronic conditions, such as coronary heart disease, dementia, stroke, fractures, and breast cancer, increase with age; however, the excess risk for these conditions that can be attributed to menopause alone is uncertain. Since the publication of findings from the Women's Health Initiative that hormone therapy use is associated with serious adverse health effects in postmenopausal women, use of menopausal hormone therapy has declined...
December 12, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29221303/the-society-for-translational-medicine-clinical-practice-guidelines-for-the-postoperative-management-of-chest-tube-for-patients-undergoing-lobectomy
#2
REVIEW
Shugeng Gao, Zhongheng Zhang, Javier Aragón, Alessandro Brunelli, Stephen Cassivi, Ying Chai, Chang Chen, Chun Chen, Gang Chen, Haiquan Chen, Jin-Shing Chen, David Tom Cooke, John B Downs, Pierre-Emmanuel Falcoz, Wentao Fang, Pier Luigi Filosso, Xiangning Fu, Seth D Force, Martínez I Garutti, Diego Gonzalez-Rivas, Dominique Gossot, Henrik Jessen Hansen, Jianxing He, Jie He, Bo Laksáfoss Holbek, Jian Hu, Yunchao Huang, Mohsen Ibrahim, Andrea Imperatori, Mahmoud Ismail, Gening Jiang, Hongjing Jiang, Zhongmin Jiang, Hyun Koo Kim, Danqing Li, Gaofeng Li, Hui Li, Qiang Li, Xiaofei Li, Yin Li, Zhijun Li, Eric Lim, Chia-Chuan Liu, Deruo Liu, Lunxu Liu, Yongyi Liu, Kevin W Lobdell, Haitao Ma, Weimin Mao, Yousheng Mao, Juwei Mou, Calvin Sze Hang Ng, Nuria M Novoa, René H Petersen, Hiroyuki Oizumi, Kostas Papagiannopoulos, Cecilia Pompili, Guibin Qiao, Majed Refai, Gaetano Rocco, Erico Ruffini, Michele Salati, Agathe Seguin-Givelet, Alan Dart Loon Sihoe, Lijie Tan, Qunyou Tan, Tang Tong, Kosmas Tsakiridis, Federico Venuta, Giulia Veronesi, Nestor Villamizar, Haidong Wang, Qun Wang, Ruwen Wang, Shumin Wang, Gavin M Wright, Deyao Xie, Qi Xue, Tao Xue, Lin Xu, Shidong Xu, Songtao Xu, Tiansheng Yan, Fenglei Yu, Zhentao Yu, Chunfang Zhang, Lanjun Zhang, Tao Zhang, Xun Zhang, Xiaojing Zhao, Xuewei Zhao, Xiuyi Zhi, Qinghua Zhou
The Society for Translational Medicine and The Chinese Society for Thoracic and Cardiovascular Surgery conducted a systematic review of the literature in an attempt to improve our understanding in the postoperative management of chest tubes of patients undergoing pulmonary lobectomy. Recommendations were produced and classified based on an internationally accepted GRADE system. The following recommendations were extracted in the present review: (I) chest tubes can be removed safely with daily pleural fluid of up to 450 mL (non-chylous and non-sanguinous), which may reduce chest tube duration and hospital length of stay (2B); (II) in rare instances, e...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29215023/a-pilot-characterization-of-the-human-chronobiome
#3
Carsten Skarke, Nicholas F Lahens, Seth D Rhoades, Amy Campbell, Kyle Bittinger, Aubrey Bailey, Christian Hoffmann, Randal S Olson, Lihong Chen, Guangrui Yang, Thomas S Price, Jason H Moore, Frederic D Bushman, Casey S Greene, Gregory R Grant, Aalim M Weljie, Garret A FitzGerald
Physiological function, disease expression and drug effects vary by time-of-day. Clock disruption in mice results in cardio-metabolic, immunological and neurological dysfunction; circadian misalignment using forced desynchrony increases cardiovascular risk factors in humans. Here we integrated data from remote sensors, physiological and multi-omics analyses to assess the feasibility of detecting time dependent signals - the chronobiome - despite the "noise" attributable to the behavioral differences of free-living human volunteers...
December 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29206465/testing-the-equivalence-between-spatial-averaging-and-temporal-averaging-in-highly-dilute-solutions
#4
Keith M Carroll, Colin Rawlings, Yadong Zhang, Armin W Knoll, Seth R Marder, Heiko Wolf, Urs Duerig
Diffusion relates the flux of particles to the local gradient of the particle density in a deterministic way. The question arises what happens when the particle density is so low that the local gradient becomes an ill-defined concept. The dilemma was resolved early last century by analyzing the average motion of particles subject to random forces whose magnitude is such that the particles are always in thermal equilibrium with their environment. The diffusion dynamics are now described in terms of a probability density of finding a particle at some position and time and a probabilistic flux density which is proportional to the gradient of the probability density...
December 5, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29203261/preoperative-computed-tomography-guided-pulmonary-lesion-marking-in-preparation-for-fluoroscopic-wedge-resection-rates-of-success-complications-and-pathology-outcomes
#5
Babatunde Olaiya, Charles A Gilliland, Seth D Force, Felix G Fernandez, Manu S Sancheti, William C Small
PURPOSE: In this study, we describe our experience of lesion marking with fiducial markers (FM) and microcoils (MC) facilitating same-day surgical wedge resection, including success rates, pathology outcomes, and complications. We also explored patient/nodular characteristics associated with developing complications. MATERIALS AND METHODS: An IRB-approved single-institutional retrospective study of 136 patients who had 148 pulmonary nodules was conducted. All patients had CT-guided pulmonary nodule labeling with either FM (121) or MC (15) patients with plan for same-day fluoroscopic-guided wedge resection...
November 6, 2017: Current Problems in Diagnostic Radiology
https://www.readbyqxmd.com/read/29174780/hospitalization-costs-after-surgery-in-high-risk-patients-with-early-stage-lung-cancer
#6
Manu S Sancheti, Ray K Chihara, Sebastian D Perez, Onkar V Khullar, Felix G Fernandez, Allan Pickens, Seth D Force
BACKGROUND: We previously reported that early stage lung cancer patients who are considered high risk for surgery can undergo resection with favorable perioperative results and long-term mortality. To further elucidate the role of surgical resection in this patient cohort, this study evaluated the length of stay and total hospitalization cost among patients classified as standard or high risk with early stage lung cancer who underwent pulmonary resection. METHODS: A total of 490 patients from our institutional Society of Thoracic Surgeons data from 2009 to 2013 underwent resection for clinical stage I lung cancer...
November 23, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29090988/youth-baseball-pitching-mechanics-a-systematic-review
#7
Samuel F Thompson, Trent M Guess, Andreas C Plackis, Seth L Sherman, Aaron D Gray
CONTEXT: Pitching injuries in youth baseball are increasing in incidence. Poor pitching mechanics in young throwers have not been sufficiently evaluated due to the lack of a basic biomechanical understanding of the "normal" youth pitching motion. OBJECTIVE: To provide a greater understanding of the kinetics and kinematics of the youth baseball pitching motion. DATA SOURCES: PubMed, MEDLINE, and SPORTDiscus databases were searched from database inception through February 2017...
November 1, 2017: Sports Health
https://www.readbyqxmd.com/read/29082386/to-three-or-not-to-three-improving-human-computation-game-onboarding-with-a-three-star-system
#8
Jacqueline Gaston, Seth Cooper
While many popular casual games use three-star systems, which give players up to three stars based on their performance in a level, this technique has seen limited application in human computation games (HCGs). This gives rise to the question of what impact, if any, a three-star system will have on the behavior of players in HCGs. In this work, we examined the impact of a three-star system implemented in the protein folding HCG Foldit. We compared the basic game's introductory levels with two versions using a three-star system, where players were rewarded with more stars for completing levels in fewer moves...
2017: Proceedings of the SIGCHI Conference on Human Factors in Computing Systems
https://www.readbyqxmd.com/read/29035526/interplay-among-sequence-folding-propensity-and-bio-piezoelectric-response-in-short-peptides-and-peptoids
#9
Christopher W Marvin, Haley M Grimm, Nathaniel C Miller, W Seth Horne, Geoffrey R Hutchison
Many biomaterials are piezoelectric (i.e., mechanically deform under an applied electric field); however, the molecular origin of this phenomenon remains unclear. In the case of protein-based scaffolds, one possibility involves flexible response of local folding motifs to the applied field. Here, we test this hypothesis by examining the piezoresponse in a series of helical peptide-based oligomers. Control over folding propensity is exerted through systematic variation in both side-chain sequence and backbone composition...
October 30, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28931634/improved-prediction-accuracy-for-disease-risk-mapping-using-gaussian-process-stacked-generalization
#10
Samir Bhatt, Ewan Cameron, Seth R Flaxman, Daniel J Weiss, David L Smith, Peter W Gething
Maps of infectious disease-charting spatial variations in the force of infection, degree of endemicity and the burden on human health-provide an essential evidence base to support planning towards global health targets. Contemporary disease mapping efforts have embraced statistical modelling approaches to properly acknowledge uncertainties in both the available measurements and their spatial interpolation. The most common such approach is Gaussian process regression, a mathematical framework composed of two components: a mean function harnessing the predictive power of multiple independent variables, and a covariance function yielding spatio-temporal shrinkage against residual variation from the mean...
September 2017: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/28919394/concomitant-chemotherapy-and-radiotherapy-with-sbrt-boost-for-unresectable-stage-iii-non-small-cell-lung-cancer-a-phase-i-study
#11
Kristin A Higgins, Rathi N Pillai, Zhengjia Chen, Sibo Tian, Chao Zhang, Pretesh Patel, Suchita Pakkala, Jay Shelton, Seth D Force, Felix G Fernandez, Conor E Steuer, Taofeek K Owonikoko, Suresh S Ramalingam, Jeffrey D Bradley, Walter J Curran
OBJECTIVES: Stereotactic body radiation therapy (SBRT) is now the standard of care in medically inoperable stage I NSCLC, yielding high rates of local control. It is unknown whether SBRT can be safely utilized in the locally advanced NSCLC setting. This multi-institution phase I study evaluated the safety of 44 Gy of conventionally fractionated thoracic radiation with concurrent chemotherapy plus dose-escalated SBRT boost to both the primary tumor and involved mediastinal lymph nodes...
November 2017: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/28888567/biomechanics-of-the-acute-boutonniere-deformity
#12
Luis Grau, Hasan Baydoun, Kevin Chen, Seth T Sankary, Farid Amirouche, Mark H Gonzalez
PURPOSE: To demonstrate which structures of the extensor mechanism create a boutonniere deformity, when damaged, in a cadaver model. An analysis of how damage to these anatomical structures affects the biomechanical performance of the extensor mechanism was also performed. METHODS: We secured 18 fresh cadaveric hands onto an apparatus consisting of a computer-controlled motor and tensiometer attached in series to the extensor communis tendon of the ring and middle digits...
September 7, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/28873168/vision-screening-in-children-aged-6-months-to-5-years-us-preventive-services-task-force-recommendation-statement
#13
David C Grossman, Susan J Curry, Douglas K Owens, Michael J Barry, Karina W Davidson, Chyke A Doubeni, John W Epling, Alex R Kemper, Alex H Krist, Ann E Kurth, C Seth Landefeld, Carol M Mangione, Maureen G Phipps, Michael Silverstein, Melissa A Simon, Chien-Wen Tseng
Importance: One of the most important causes of vision abnormalities in children is amblyopia (also known as "lazy eye"). Amblyopia is an alteration in the visual neural pathway in a child's developing brain that can lead to permanent vision loss in the affected eye. Among children younger than 6 years, 1% to 6% have amblyopia or its risk factors (strabismus, anisometropia, or both). Early identification of vision abnormalities could prevent the development of amblyopia. Subpopulation Considerations: Studies show that screening rates among children vary by race/ethnicity and family income...
September 5, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28860003/sleep-restriction-induced-energy-methylation-and-lipogenesis-metabolic-switches-in-rat-liver
#14
Arjun Sengupta, Seth D Rhoades, Eun Ji Kim, Soumyashant Nayak, Gregory R Grant, Peter Meerlo, Aalim M Weljie
Sleep curtailment is ubiquitous in modern day society. Sleep debt is associated with maladaptive physiological changes that can lead to cardiometabolic and neuropsychiatric pathologies. Recent literature has shown the effects of sleep restriction (SR) on systemic metabolic profiles in biofluids, implying that tissue-specific metabolomes are impacted by SR. To test this hypothesis, we assessed hepatic metabolic profiles of rats after 5days of SR using UPLC-MS based metabolomics analysis and gene expression analysis...
August 28, 2017: International Journal of Biochemistry & Cell Biology
https://www.readbyqxmd.com/read/28853290/modulating-hole-transport-in-multilayered-photocathodes-with-derivatized-p-type-nickel-oxide-and-molecular-assemblies-for-solar-driven-water-splitting
#15
Bing Shan, Benjamin D Sherman, Christina M Klug, Animesh Nayak, Seth L Marquard, Qing Liu, R Morris Bullock, Thomas J Meyer
For solar water splitting, dye-sensitized NiO photocathodes have been a primary target. Despite marginal improvement in performance, limitations remain arising from the intrinsic disadvantages of NiO and insufficient catalysis. We report here a new approach to modifying NiO photocathodes with doped NiO bilayers and an additional layer of macro-mesoporous ITO. The trilayered electrode is functionalized with a surface-attached ruthenium polypyridyl dye and a covalently bridged nickel-based hydrogen evolution catalyst...
August 31, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28846505/development-and-validation-of-a-portable-and-inexpensive-tool-to-measure-the-drop-vertical-jump-using-the-microsoft-kinect-v2
#16
Aaron D Gray, Brad W Willis, Marjorie Skubic, Zhiyu Huo, Swithin Razu, Seth L Sherman, Trent M Guess, Amirhossein Jahandar, Trevor R Gulbrandsen, Scott Miller, Nathan J Siesener
BACKGROUND: Noncontact anterior cruciate ligament (ACL) injury in adolescent female athletes is an increasing problem. The knee-ankle separation ratio (KASR), calculated at initial contact (IC) and peak flexion (PF) during the drop vertical jump (DVJ), is a measure of dynamic knee valgus. The Microsoft Kinect V2 has shown promise as a reliable and valid marker-less motion capture device. HYPOTHESIS: The Kinect V2 will demonstrate good to excellent correlation between KASR results at IC and PF during the DVJ, as compared with a "gold standard" Vicon motion analysis system...
November 2017: Sports Health
https://www.readbyqxmd.com/read/28813912/transverse-forces-versus-modified-ashworth-scale-for-upper-limb-flexion-extension-in-para-sagittal-plane
#17
Nitin Seth, Denise Johnson, Hussein A Abdullah
Spasticity is a common impairment following an upper motor neuron lesion in conditions such as stroke and brain injury. A clinical issue is how to best quantify and measure spasticity. Recently, research has been performed to develop new methods of spasticity quantification using various systems. This paper follows up on previous work taking a closer look at the role of transversal forces obtained via rehabilitation robot for motions in the para-sagittal plane. Results from 45 healthy individuals and 40 individuals with acquired brain injury demonstrate that although the passive upper motions are vertical, horizontal forces into and away from the individual's body demonstrate a relationship with the Modified Ashworth Scale...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28754976/constraining-shifts-in-north-atlantic-plate-motions-during-the-palaeocene-by-u-pb-dating-of-svalbard-tephra-layers
#18
Morgan T Jones, Lars E Augland, Grace E Shephard, Seth D Burgess, Gauti T Eliassen, Malte M Jochmann, Bjarki Friis, Dougal A Jerram, Sverre Planke, Henrik H Svensen
Radioisotopic dating of volcanic minerals is a powerful method for establishing absolute time constraints in sedimentary basins, which improves our understanding of the chronostratigraphy and evolution of basin processes. The relative plate motions of Greenland, North America, and Eurasia changed several times during the Palaeogene. However, the timing of a key part of this sequence, namely the initiation of compression between Greenland and Svalbard, is currently poorly constrained. The formation of the Central Basin in Spitsbergen is inherently linked to changes in regional plate motions, so an improved chronostratigraphy of the sedimentary sequence is warranted...
July 28, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28734435/laparoscopic-approach-for-treatment-of-symptomatic-intra-pericardial-cyst
#19
Ray K Chihara, Seth D Force
Symptomatic pericardial cysts requiring operative management are rare entities. We present a patient with a symptomatic intra-pericardial cystic lesion with intermittent syncope who underwent treatment using a laparoscopic approach, thus minimizing pain and allowing quick recovery.
August 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28718707/child-sexual-abuse-and-adult-mental-health-sexual-risk-behaviors-and-drinking-patterns-among-latino-men-who-have-sex-with-men
#20
Ethan Czuy Levine, Omar Martinez, Brian Mattera, Elwin Wu, Sonya Arreola, Scott Edward Rutledge, Bernie Newman, Larry Icard, Miguel Muñoz-Laboy, Carolina Hausmann-Stabile, Seth Welles, Scott D Rhodes, Brian M Dodge, Sarah Alfonso, M Isabel Fernandez, Alex Carballo-Diéguez
One in five Latino men who have sex with men has experienced child sexual abuse. Although concerning in itself, child sexual abuse may increase an individuals' likelihood of depression and risk-taking in adult life, including engagement in HIV risk behaviors and alcohol and substance use. It is therefore urgent that researchers and practitioners better understand the long-term effects of child sexual abuse. We utilized logistic and linear regression to assess associations between child sexual abuse (operationalized as forced or coerced sexual activity before age 17) and depression, sexual behaviors, and drinking patterns in a sample of 176 adult Latino men who have sex with men from New York City...
July 18, 2017: Journal of Child Sexual Abuse
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