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Felix Fernandez

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https://www.readbyqxmd.com/read/28093872/nitrogenated-azaphilone-derivatives-through-a-silver-catalysed-reaction-of-imines-of-ortho-alkynylbenzaldehydes
#1
Félix Rodríguez, Patricia Fernández, Francisco Javier Fañanás
Nitrogenated azaphilones are interesting natural products with wide range of applications whose structure is characterized by the presence of an isoquinolinone framework. Herein, we describe a new multicomponent silver-catalysed reaction that allows the transformation of simple imines derived from ortho-alkynylbenzaldehydes into complex nitrogenated azaphilone-type molecules in a straightforward way. This atom-economical process is high yielding, technically very simple and proceeds through a series of cascade processes that imply cycloisomerization and formal cross-coupling reactions...
January 17, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28070282/the-database-of-the-predicts-projecting-responses-of-ecological-diversity-in-changing-terrestrial-systems-project
#2
Lawrence N Hudson, Tim Newbold, Sara Contu, Samantha L L Hill, Igor Lysenko, Adriana De Palma, Helen R P Phillips, Tamera I Alhusseini, Felicity E Bedford, Dominic J Bennett, Hollie Booth, Victoria J Burton, Charlotte W T Chng, Argyrios Choimes, David L P Correia, Julie Day, Susy Echeverría-Londoño, Susan R Emerson, Di Gao, Morgan Garon, Michelle L K Harrison, Daniel J Ingram, Martin Jung, Victoria Kemp, Lucinda Kirkpatrick, Callum D Martin, Yuan Pan, Gwilym D Pask-Hale, Edwin L Pynegar, Alexandra N Robinson, Katia Sanchez-Ortiz, Rebecca A Senior, Benno I Simmons, Hannah J White, Hanbin Zhang, Job Aben, Stefan Abrahamczyk, Gilbert B Adum, Virginia Aguilar-Barquero, Marcelo A Aizen, Belén Albertos, E L Alcala, Maria Del Mar Alguacil, Audrey Alignier, Marc Ancrenaz, Alan N Andersen, Enrique Arbeláez-Cortés, Inge Armbrecht, Víctor Arroyo-Rodríguez, Tom Aumann, Jan C Axmacher, Badrul Azhar, Adrián B Azpiroz, Lander Baeten, Adama Bakayoko, András Báldi, John E Banks, Sharad K Baral, Jos Barlow, Barbara I P Barratt, Lurdes Barrico, Paola Bartolommei, Diane M Barton, Yves Basset, Péter Batáry, Adam J Bates, Bruno Baur, Erin M Bayne, Pedro Beja, Suzan Benedick, Åke Berg, Henry Bernard, Nicholas J Berry, Dinesh Bhatt, Jake E Bicknell, Jochen H Bihn, Robin J Blake, Kadiri S Bobo, Roberto Bóçon, Teun Boekhout, Katrin Böhning-Gaese, Kevin J Bonham, Paulo A V Borges, Sérgio H Borges, Céline Boutin, Jérémy Bouyer, Cibele Bragagnolo, Jodi S Brandt, Francis Q Brearley, Isabel Brito, Vicenç Bros, Jörg Brunet, Grzegorz Buczkowski, Christopher M Buddle, Rob Bugter, Erika Buscardo, Jörn Buse, Jimmy Cabra-García, Nilton C Cáceres, Nicolette L Cagle, María Calviño-Cancela, Sydney A Cameron, Eliana M Cancello, Rut Caparrós, Pedro Cardoso, Dan Carpenter, Tiago F Carrijo, Anelena L Carvalho, Camila R Cassano, Helena Castro, Alejandro A Castro-Luna, Cerda B Rolando, Alexis Cerezo, Kim Alan Chapman, Matthieu Chauvat, Morten Christensen, Francis M Clarke, Daniel F R Cleary, Giorgio Colombo, Stuart P Connop, Michael D Craig, Leopoldo Cruz-López, Saul A Cunningham, Biagio D'Aniello, Neil D'Cruze, Pedro Giovâni da Silva, Martin Dallimer, Emmanuel Danquah, Ben Darvill, Jens Dauber, Adrian L V Davis, Jeff Dawson, Claudio de Sassi, Benoit de Thoisy, Olivier Deheuvels, Alain Dejean, Jean-Louis Devineau, Tim Diekötter, Jignasu V Dolia, Erwin Domínguez, Yamileth Dominguez-Haydar, Silvia Dorn, Isabel Draper, Niels Dreber, Bertrand Dumont, Simon G Dures, Mats Dynesius, Lars Edenius, Paul Eggleton, Felix Eigenbrod, Zoltán Elek, Martin H Entling, Karen J Esler, Ricardo F de Lima, Aisyah Faruk, Nina Farwig, Tom M Fayle, Antonio Felicioli, Annika M Felton, Roderick J Fensham, Ignacio C Fernandez, Catarina C Ferreira, Gentile F Ficetola, Cristina Fiera, Bruno K C Filgueiras, Hüseyin K Fırıncıoğlu, David Flaspohler, Andreas Floren, Steven J Fonte, Anne Fournier, Robert E Fowler, Markus Franzén, Lauchlan H Fraser, Gabriella M Fredriksson, Geraldo B Freire, Tiago L M Frizzo, Daisuke Fukuda, Dario Furlani, René Gaigher, Jörg U Ganzhorn, Karla P García, Juan C Garcia-R, Jenni G Garden, Ricardo Garilleti, Bao-Ming Ge, Benoit Gendreau-Berthiaume, Philippa J Gerard, Carla Gheler-Costa, Benjamin Gilbert, Paolo Giordani, Simonetta Giordano, Carly Golodets, Laurens G L Gomes, Rachelle K Gould, Dave Goulson, Aaron D Gove, Laurent Granjon, Ingo Grass, Claudia L Gray, James Grogan, Weibin Gu, Moisès Guardiola, Nihara R Gunawardene, Alvaro G Gutierrez, Doris L Gutiérrez-Lamus, Daniela H Haarmeyer, Mick E Hanley, Thor Hanson, Nor R Hashim, Shombe N Hassan, Richard G Hatfield, Joseph E Hawes, Matt W Hayward, Christian Hébert, Alvin J Helden, John-André Henden, Philipp Henschel, Lionel Hernández, James P Herrera, Farina Herrmann, Felix Herzog, Diego Higuera-Diaz, Branko Hilje, Hubert Höfer, Anke Hoffmann, Finbarr G Horgan, Elisabeth Hornung, Roland Horváth, Kristoffer Hylander, Paola Isaacs-Cubides, Hiroaki Ishida, Masahiro Ishitani, Carmen T Jacobs, Víctor J Jaramillo, Birgit Jauker, F Jiménez Hernández, McKenzie F Johnson, Virat Jolli, Mats Jonsell, S Nur Juliani, Thomas S Jung, Vena Kapoor, Heike Kappes, Vassiliki Kati, Eric Katovai, Klaus Kellner, Michael Kessler, Kathryn R Kirby, Andrew M Kittle, Mairi E Knight, Eva Knop, Florian Kohler, Matti Koivula, Annette Kolb, Mouhamadou Kone, Ádám Kőrösi, Jochen Krauss, Ajith Kumar, Raman Kumar, David J Kurz, Alex S Kutt, Thibault Lachat, Victoria Lantschner, Francisco Lara, Jesse R Lasky, Steven C Latta, William F Laurance, Patrick Lavelle, Violette Le Féon, Gretchen LeBuhn, Jean-Philippe Légaré, Valérie Lehouck, María V Lencinas, Pia E Lentini, Susan G Letcher, Qi Li, Simon A Litchwark, Nick A Littlewood, Yunhui Liu, Nancy Lo-Man-Hung, Carlos A López-Quintero, Mounir Louhaichi, Gabor L Lövei, Manuel Esteban Lucas-Borja, Victor H Luja, Matthew S Luskin, M Cristina MacSwiney G, Kaoru Maeto, Tibor Magura, Neil Aldrin Mallari, Louise A Malone, Patrick K Malonza, Jagoba Malumbres-Olarte, Salvador Mandujano, Inger E Måren, Erika Marin-Spiotta, Charles J Marsh, E J P Marshall, Eliana Martínez, Guillermo Martínez Pastur, David Moreno Mateos, Margaret M Mayfield, Vicente Mazimpaka, Jennifer L McCarthy, Kyle P McCarthy, Quinn S McFrederick, Sean McNamara, Nagore G Medina, Rafael Medina, Jose L Mena, Estefania Mico, Grzegorz Mikusinski, Jeffrey C Milder, James R Miller, Daniel R Miranda-Esquivel, Melinda L Moir, Carolina L Morales, Mary N Muchane, Muchai Muchane, Sonja Mudri-Stojnic, A Nur Munira, Antonio Muoñz-Alonso, B F Munyekenye, Robin Naidoo, A Naithani, Michiko Nakagawa, Akihiro Nakamura, Yoshihiro Nakashima, Shoji Naoe, Guiomar Nates-Parra, Dario A Navarrete Gutierrez, Luis Navarro-Iriarte, Paul K Ndang'ang'a, Eike L Neuschulz, Jacqueline T Ngai, Violaine Nicolas, Sven G Nilsson, Norbertas Noreika, Olivia Norfolk, Jorge Ari Noriega, David A Norton, Nicole M Nöske, A Justin Nowakowski, Catherine Numa, Niall O'Dea, Patrick J O'Farrell, William Oduro, Sabine Oertli, Caleb Ofori-Boateng, Christopher Omamoke Oke, Vicencio Oostra, Lynne M Osgathorpe, Samuel Eduardo Otavo, Navendu V Page, Juan Paritsis, Alejandro Parra-H, Luke Parry, Guy Pe'er, Peter B Pearman, Nicolás Pelegrin, Raphaël Pélissier, Carlos A Peres, Pablo L Peri, Anna S Persson, Theodora Petanidou, Marcell K Peters, Rohan S Pethiyagoda, Ben Phalan, T Keith Philips, Finn C Pillsbury, Jimmy Pincheira-Ulbrich, Eduardo Pineda, Joan Pino, Jaime Pizarro-Araya, A J Plumptre, Santiago L Poggio, Natalia Politi, Pere Pons, Katja Poveda, Eileen F Power, Steven J Presley, Vânia Proença, Marino Quaranta, Carolina Quintero, Romina Rader, B R Ramesh, Martha P Ramirez-Pinilla, Jai Ranganathan, Claus Rasmussen, Nicola A Redpath-Downing, J Leighton Reid, Yana T Reis, José M Rey Benayas, Juan Carlos Rey-Velasco, Chevonne Reynolds, Danilo Bandini Ribeiro, Miriam H Richards, Barbara A Richardson, Michael J Richardson, Rodrigo Macip Ríos, Richard Robinson, Carolina A Robles, Jörg Römbke, Luz Piedad Romero-Duque, Matthias Rös, Loreta Rosselli, Stephen J Rossiter, Dana S Roth, T'ai H Roulston, Laurent Rousseau, André V Rubio, Jean-Claude Ruel, Jonathan P Sadler, Szabolcs Sáfián, Romeo A Saldaña-Vázquez, Katerina Sam, Ulrika Samnegård, Joana Santana, Xavier Santos, Jade Savage, Nancy A Schellhorn, Menno Schilthuizen, Ute Schmiedel, Christine B Schmitt, Nicole L Schon, Christof Schüepp, Katharina Schumann, Oliver Schweiger, Dawn M Scott, Kenneth A Scott, Jodi L Sedlock, Steven S Seefeldt, Ghazala Shahabuddin, Graeme Shannon, Douglas Sheil, Frederick H Sheldon, Eyal Shochat, Stefan J Siebert, Fernando A B Silva, Javier A Simonetti, Eleanor M Slade, Jo Smith, Allan H Smith-Pardo, Navjot S Sodhi, Eduardo J Somarriba, Ramón A Sosa, Grimaldo Soto Quiroga, Martin-Hugues St-Laurent, Brian M Starzomski, Constanti Stefanescu, Ingolf Steffan-Dewenter, Philip C Stouffer, Jane C Stout, Ayron M Strauch, Matthew J Struebig, Zhimin Su, Marcela Suarez-Rubio, Shinji Sugiura, Keith S Summerville, Yik-Hei Sung, Hari Sutrisno, Jens-Christian Svenning, Tiit Teder, Caragh G Threlfall, Anu Tiitsaar, Jacqui H Todd, Rebecca K Tonietto, Ignasi Torre, Béla Tóthmérész, Teja Tscharntke, Edgar C Turner, Jason M Tylianakis, Marcio Uehara-Prado, Nicolas Urbina-Cardona, Denis Vallan, Adam J Vanbergen, Heraldo L Vasconcelos, Kiril Vassilev, Hans A F Verboven, Maria João Verdasca, José R Verdú, Carlos H Vergara, Pablo M Vergara, Jort Verhulst, Massimiliano Virgilio, Lien Van Vu, Edward M Waite, Tony R Walker, Hua-Feng Wang, Yanping Wang, James I Watling, Britta Weller, Konstans Wells, Catrin Westphal, Edward D Wiafe, Christopher D Williams, Michael R Willig, John C Z Woinarski, Jan H D Wolf, Volkmar Wolters, Ben A Woodcock, Jihua Wu, Joseph M Wunderle, Yuichi Yamaura, Satoko Yoshikura, Douglas W Yu, Andrey S Zaitsev, Juliane Zeidler, Fasheng Zou, Ben Collen, Rob M Ewers, Georgina M Mace, Drew W Purves, Jörn P W Scharlemann, Andy Purvis
The PREDICTS project-Projecting Responses of Ecological Diversity In Changing Terrestrial Systems (www.predicts.org.uk)-has collated from published studies a large, reasonably representative database of comparable samples of biodiversity from multiple sites that differ in the nature or intensity of human impacts relating to land use. We have used this evidence base to develop global and regional statistical models of how local biodiversity responds to these measures. We describe and make freely available this 2016 release of the database, containing more than 3...
January 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28069553/targeting-inflammasome-by-the-inhibition-of-caspase-1-activity-using-capped-mesoporous-silica-nanoparticles
#3
Alba García-Fernández, Guillermo García-Laínez, María Luisa Ferrándiz, Elena Aznar, Félix Sancenón, María José Alcaraz, José Ramón Murguía, María D Marcos, Ramón Martínez-Máñez, Ana M Costero, Mar Orzáez
Acute inflammation is a protective response of the body to harmful stimuli, such as pathogens or damaged cells. However, dysregulated inflammation can cause secondary damage and could thus contribute to the pathophysiology of many diseases. Inflammasomes, the macromolecular complexes responsible for caspase-1 activation, have emerged as key regulators of immune and inflammatory responses. Therefore, modulation of inflammasome activity has become an important therapeutic approach. Here we describe the design of a smart nanodevice that takes advantage of the passive targeting of nanoparticles to macrophages and enhances the therapeutic effect of caspase-1 inhibitor VX-765 in vivo...
January 6, 2017: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/28058548/minimally-invasive-and-open-approaches-to-mediastinal-nodal-assessment
#4
Crystal J Erickson, Felix G Fernandez, Rishindra M Reddy
There is no consensus on mediastinal lymph node dissection versus sampling for early-stage lung cancer. There are also mixed data on the ability to remove an adequate number of lymph nodes by a minimally invasive approach. In this review, we discuss the difference between dissection and sampling, what circumstances dictate the use of one or the other during an anatomic pulmonary resection for lung cancer, and when it is appropriate to use minimally invasive versus open approaches in the assessment of mediastinal nodes...
January 5, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28031716/diagnostic-accuracy-of-nodular-gastritis-for-h-pylori-infection
#5
Juan L Romero-Flores, Justo A Fernandez-Rivero, Erika Marroquín-Fabian, Félix I Téllez-Ávila, Beatriz A Sánchez-Jiménez, Eva Juárez-Hernández, Misael Uribe, Norberto C Chávez-Tapia
BACKGROUND: The term nodular is not included in the Sydney classification and there is no widely accepted histopathological definition. It has been proposed that the presence of antral nodularity could predict Helicobacter pylori (H. pylori) infection. The aim of this study was to determine the diagnostic accuracy of nodular gastritis (NG) for H. pylori infection after a rigorous standardization process, and to describe the associated histopathological characteristics. MATERIALS AND METHODS: Endoscopic images of patients submitted to endoscopy with biopsy sampling were included...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/27992220/synthesis-of-functionalized-1h-indenes-and-benzofulvenes-through-iodocyclization-of-o-alkynyl-styrenes
#6
Patricia García-García, Ana M Sanjuán, Muhammad A Rashid, Alberto Martínez-Cuezva, Manuel A Fernández-Rodríguez, Félix Rodríguez, Roberto Sanz
A convenient method for the preparation of synthetically useful 3-iodoindene derivatives has been developed. This protocol, based on the 5-endo iodocyclization reaction of o-(alkynyl)styrenes, represents one of the scarce examples of halocyclizations using olefins as nucleophilic counterparts and allows the synthesis of both 3-iodo-1H-indenes (from β-alkyl-β-alkyl/aryl-o-(alkynyl)styrenes) and 3-iodobenzofulvenes (from β,β-diaryl-o-(alkynyl)styrenes) in good yields under mild reaction conditions. In addition, related alkoxyiodocyclization processes are described, which are particularly interesting in their intramolecular version because they allow the synthesis of heteropolycyclic structures containing the indene core...
December 30, 2016: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/27989941/a-multicentric-study-to-evaluate-the-use-of-relative-retention-times-in-targeted-proteomics
#7
Vital Vialas, Núria Colomé-Calls, Joaquín Abian, Kerman Aloria, Gloria Alvarez-Llamas, Oreto Antúnez, Jesus M Arizmendi, Mikel Azkargorta, Silvia Barceló-Batllori, María G Barderas, Francisco Blanco, J Ignacio Casal, Vanessa Casas, Carolina de la Torre, Eduardo Chicano-Gálvez, Felix Elortza, Guadalupe Espadas, Josep M Estanyol, Joaquín Fernandez-Irigoyen, Patricia Fernandez-Puente, María José Fidalgo, Manuel Fuentes, Marina Gay, Concha Gil, Alexandre Hainard, Maria Luisa Hernaez, Nieves Ibarrola, Arthur T Kopylov, Antonio Lario, Juan Antonio Lopez, María López-Lucendo, Miguel Marcilla, Anabel Marina-Ramírez, Gyorgy Marko-Varga, Luna Martín, Maria I Mora, Esperanza Morato-López, Javier Muñoz, Maria Antonia Odena, Eliandre de Oliveira, Irene Orera, Ignacio Ortea, Carla Pasquarello, Kevin B Ray, Melinda Rezeli, Isabel Ruppen, Eduard Sabidó, Manuel M Sanchez Del Pino, Jaime Sancho, Enrique Santamaría, Jesus Vazquez, Marta Vilaseca, Fernando Vivanco, James J Walters, Victor G Zgoda, Fernando J Corrales, Francesc Canals, Alberto Paradela
: Despite the maturity reached by targeted proteomic strategies, reliable and standardized protocols are urgently needed to enhance reproducibility among different laboratories and analytical platforms, facilitating a more widespread use in biomedical research. To achieve this goal, the use of dimensionless relative retention times (iRT), defined on the basis of peptide standard retention times (RT), has lately emerged as a powerful tool. The robustness, reproducibility and utility of this strategy were examined for the first time in a multicentric setting, involving 28 laboratories that included 24 of the Spanish network of proteomics laboratories (ProteoRed-ISCIII)...
January 30, 2017: Journal of Proteomics
https://www.readbyqxmd.com/read/27980740/multiple-primary-cutaneous-plasmacytoma-a-decade-after-a-nasal-solitary-extramedullary-plasmacytoma-a-puzzling-case
#8
Verónica González-Calle, Conrado Jorge-Finnigan, Juan Carlos Santos-Durán, Felix López-Cadenas, Enrique María Ocio, Ramón García-Sanz, Ángel Santos-Briz, Emilia Fernández-López, Jesús San Miguel, María-Victoria Mateos, Concha Román-Curto
Primary cutaneous plasmacytoma should be in the differential diagnosis in case of solitary or multiple erythematous-violaceous nodules or papules. The diagnosis relies on clinical, histological, and immunochemical findings, without underlying evidence of multiple myeloma. Treatment should be individualized, and agents such as bortezomib or lenalidomide have shown to be effective.
December 2016: Clinical Case Reports
https://www.readbyqxmd.com/read/27911956/adenosine-stimulate-proliferation-and-migration-in-triple-negative-breast-cancer-cells
#9
Miriam Fernandez-Gallardo, Ricardo González-Ramírez, Alejandro Sandoval, Ricardo Felix, Eduardo Monjaraz
Emerging evidence suggests that the adenosine (Ado) receptors may play crucial roles in tumor progression. Here, we show that Ado increases proliferation and migration in a triple negative breast cancer model, the MDA-MB 231 cell line. The use of specific agonists and antagonists evidenced that these effects depend on the activation of the A2B receptor, which then triggers an intracellular response mediated by the adenylate cyclase/PKA/cAMP signaling pathway. Ado also increases the expression of NaV1.5 channels, a potential biomarker in breast cancer...
2016: PloS One
https://www.readbyqxmd.com/read/27908772/anaplasma-platys-in-dogs-from-uruguay
#10
Luis Carvalho, Maria Teresa Armua-Fernandez, Nicolás Sosa, María Laura Félix, José Manuel Venzal
Anaplasmataceae family members include vector-borne bacteria of veterinary importance that may also affect humans. Ehrlichia canis and Anaplasma platys are the main members of this family detected in dogs worldwide. In Uruguay there are not many published studies on tick-borne pathogens affecting dogs, the only haemoparasite molecularly confirmed in dogs, is the piroplasm Rangelia vitalii. The aim of the present work was to detect the presence of A. platys and E. canis in dogs and dogs-associated ticks of two localities in Northwestern Uruguay...
November 17, 2016: Ticks and Tick-borne Diseases
https://www.readbyqxmd.com/read/27851286/1651-intravascular-cooling-catheter-related-venous-thromboembolism-after-hypothermia-protocol
#11
Xuan Wang, Brian Moy, Felix Krainski, Victoria Forbes, William Duvall, Antonio Fernandez
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27847042/the-society-of-thoracic-surgeons-national-database-2016-annual-report
#12
Jeffrey P Jacobs, David M Shahian, Richard L Prager, Fred H Edwards, Donna McDonald, Jane M Han, Richard S D'Agostino, Marshall L Jacobs, Benjamin D Kozower, Vinay Badhwar, Vinod H Thourani, Henning A Gaissert, Felix G Fernandez, Cameron D Wright, Gaetano Paone, Joseph C Cleveland, J Matthew Brennan, Rachel S Dokholyan, Leo Brothers, Sreekanth Vemulapalli, Robert H Habib, Sean M O'Brien, Eric D Peterson, Frederick L Grover, G Alexander Patterson, Joseph E Bavaria
The art and science of outcomes analysis, quality improvement, and patient safety continue to evolve, and cardiothoracic surgery leads many of these advances. The Society of Thoracic Surgeons (STS) National Database is one of the principal reasons for this leadership role, as it provides a platform for the generation of knowledge in all of these domains. Understanding these topics is a professional responsibility of all cardiothoracic surgeons. Therefore, beginning in January 2016, The Annals of Thoracic Surgery began publishing a monthly series of scholarly articles on outcomes analysis, quality improvement, and patient safety...
December 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27823711/central-sleep-apnea-in-children-experience-at-a-single-center
#13
Orlane Felix, Alessandro Amaddeo, Jorge Olmo Arroyo, Michel Zerah, Stephanie Puget, Valerie Cormier-Daire, Genevieve Baujat, Graziella Pinto, Marta Fernandez-Bolanos, Brigitte Fauroux
OBJECTIVE: Central sleep apnea (CSA) syndromes are rare in children and data in children over one year of age are scarce. The aim of the study was to describe the sleep characteristics, underlying disorders, management, and outcome of children with CSA. PATIENTS/METHODS: A retrospective chart review of all children >1 year of age, diagnosed with CSA on a laboratory sleep study during a 20-month period, was performed. CSA was defined by a central apnea index (CAI) >5 events/h...
September 2016: Sleep Medicine
https://www.readbyqxmd.com/read/27821895/health-care-utilization-of-mexican-patients-with-medically-unexplained-physical-symptoms
#14
Azucena Maribel Rodriguez González, José Manuel Ramírez Aranda, Homero de Los Santos Reséndiz, María Yolanda Lara Duarte, Santiago Oscar Pazaran Zanella, Jafet Felipe Méndez López, Issa Gil Alfaro, Félix Gilberto Islas Ruz, Gloria Navarrete Floriano, Edith Guillen Salomón, Obdulia Texon Fernández, Silvia Cruz Duarte, Juan Carlos Romo Salazar, Claudia Elsa Pérez Ruiz, Sara de Jesús López Salas, Lizbeth Benítez Amaya, Javier Nahum Zapata Gallardo
OBJECTIVE: To determine the prevalence of medically unexplained physical symptoms and the characteristics and use of health services in a group of patients with medically unexplained physical symptoms and a group of patients with other illnesses. METHODS: This was a cross-sectional, retrospective and multicenter study. We included 1,043 patients over 18 years of age from 30 primary care units of a government health institution, in 11 states of Mexico, attended by 39 family physicians...
September 30, 2016: Colombia Médica: CM
https://www.readbyqxmd.com/read/27815703/development-of-an-activity-disease-score-in-patients-with-uveitis-uvedai
#15
Esperanza Pato, Mª Auxiliadora Martin-Martinez, Adela Castelló, Rosalía Méndez-Fernandez, Santiago Muñoz-Fernández, Miguel Cordero-Coma, Lucia Martinez-Costa, Elia Valls, Miguel Reyes, Félix Francisco, Mar Esteban, Alex Fonollosa, Fernando Sanchez-Alonso, Cruz Fernández-Espartero, Teresa Diaz-Valle, José Miguel Carrasco, Emma Beltran-Catalán, Marisa Hernández-Garfella, María Victoria Hernández, Laura Pelegrin, Ricardo Blanco, David Diaz-Valle
To develop a disease activity index for patients with uveitis (UVEDAI) encompassing the relevant domains of disease activity considered important among experts in this field. The steps for designing UVEDAI were: (a) Defining the construct and establishing the domains through a formal judgment of experts, (b) A two-round Delphi study with a panel of 15 experts to determine the relevant items, (c) Selection of items: A logistic regression model was developed that set ocular inflammatory activity as the dependent variable...
November 4, 2016: Rheumatology International
https://www.readbyqxmd.com/read/27809369/luminescent-thermochromism-of-2d-coordination-polymers-based-on-copper-i-halides-with-4-hydroxythiophenol
#16
Javier Troyano, Josefina Perles, Pilar Amo-Ochoa, Jose Ignacio Martínez, Maria Concepción Gimeno, Vanesa Fernández-Moreira, Félix Zamora, Salomé Delgado
Solvothermal reactions between copper(I) halides and 4-mercaptophenol give rise to the formation of three coordination polymers with general formula [Cu3 X(HT)2 ]n (X=Cl, 1; Br, 2; and I, 3). The structures of these coordination polymers have been determined by X-ray diffraction at both room- and low temperature (110 K), showing a general shortening in Cu-S, Cu-X and Cu-Cu bond lengths at low temperatures. 1 and 2 are isostructural, consisting of layers in which the halogen ligands act as μ3 -bridges joining two Cu1 and one Cu2 atoms whereas in 3 the iodine ligands is as μ4 -mode but the layers are quasi-isostructural with 1 or 2...
December 12, 2016: Chemistry: a European Journal
https://www.readbyqxmd.com/read/27804302/unexpected-cation-dynamics-in-the-low-temperature-phase-of-methylammonium-lead-iodide-the-need-for-improved-models
#17
Kacper Drużbicki, Roberto Simone Pinna, Svemir Rudić, Marek Jura, Giuseppe Gorini, Felix Fernandez-Alonso
High-resolution inelastic neutron scattering and extensive first-principles calculations have been used to explore the low-temperature phase of the hybrid solar-cell material methylammonium lead iodide up to the well-known phase transition to the tetragonal phase at ca. 160 K. Contrary to original expectation, we find that the Pnma structure for this phase can only provide a qualitative description of the geometry and underlying motions of the organic cation. A substantial lowering of the local symmetry inside the perovskite cage leads to an improved atomistic model that can account for all available spectroscopic and thermodynamic data, both at low temperatures and in the vicinity of the aforementioned phase transition...
November 17, 2016: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/27801525/complement-c3f-allotype-synthesized-by-liver-recipient-modifies-transplantation-outcome-independently-from-donor-hepatic-c3
#18
Diana María Valero-Hervás, Elena Sánchez-Zapardiel, María José Castro, Fernando Gallego-Bustos, Félix Cambra, Iago Justo, Rocío Laguna-Goya, Carlos Jiménez-Romero, Enrique Moreno, Francisco López-Medrano, Rafael San Juan, Mario Fernández-Ruiz, José María Aguado, Estela Paz-Artal
Complement component 3 (C3) presents both slow (C3S) and fast (C3F) variants, which can be locally-produced and activated by immune system cells. We studied C3 recipient variants in 483 liver transplant patients by RT-PCR-HRM to determine their effect on graft outcome during the first year post-transplantation. Allograft survival was significantly decreased in C3FF recipients (C3SS 95% vs. C3FS 91% vs. C3FF 83%; p=0.01) or C3F allele carriers (C3F-absence 95% vs. C3F-presence 90%, p=0.02). C3FF genotype or presence of C3F allele independently increased risk for allograft loss (OR: 2...
November 1, 2016: Clinical Transplantation
https://www.readbyqxmd.com/read/27790648/complex-chromene-derivatives-through-a-silver-catalysed-cascade-reaction-of-simple-o-alkynylsalicylaldehydes-and-alkenes
#19
Tamara Arto, Patricia Fernández, Francisco J Fañanás, Félix Rodríguez
The silver-catalysed reaction of simple ortho-alkynylsalicylaldehydes and alkenes gives complex benzo[de]chromenyl ketones through an unusual cascade process where the starting ortho-alkynylsalicylaldehyde behaves as a bis-diene derivative that participates in two different formal [4+2]-cycloaddition reactions.
October 28, 2016: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/27776958/trends-in-stroke-hospitalisation-rates-in-extremadura-between-2002-and-2014-changing-the-notion-of-stroke-as-a-disease-of-the-elderly
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J M Ramírez-Moreno, F J Felix-Redondo, D Fernández-Bergés, L Lozano-Mera
BACKGROUND: The incidence of stroke in Spain has been evaluated in several studies, whose results are highly variable and not comparable. No studies of stroke have analysed epidemiological changes in younger patients. METHOD: We conducted a retrospective observational study using the Spanish health system's Minimum Data Set and included all patients older than 19 hospitalised due to stroke (ICD-9-CM codes 434.01, 434.11, 434.91, 430, 431, 432.9, 436, and 435) between 2002 and 2013...
October 21, 2016: Neurología: Publicación Oficial de la Sociedad Española de Neurología
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