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https://www.readbyqxmd.com/read/28626959/intramolecular-singlet-fission-in-antiaromatic-polycyclic-hydrocarbon
#1
Hongbing Fu, Yishi Wu, Yuancheng Wang, Jianwei Chen, Guanxin Zhang, Jiannian Yao, Deqing Zhang
Singlet fission (SF), in which one singlet exciton (S₁) splits into two triplets (T₁) on adjacent molecules through a correlated triplet-pair ¹(TT) state, requires precise but difficult tuning of exciton energetics and intermolecular electronic couplings in the solid state. Here we demonstrate anti-aromatic 4nπ dibenzopentalenes (DPs) as a new class of single-chromophore based intramolecular SF materials, which exhibit optically allowed S2 state with E(S₂) > 2E(T₁) and optically forbidden S₁ state...
June 19, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28625532/emergency-department-do-not-resuscitate-order-in-patients-with-spontaneous-intracerebral-hemorrhage
#2
Ju-Sing Fan, Hsien-Hao Huang, Yen-Chia Chen, Chorng-Kuang How, David Hung-Tsang Yen
OBJECTIVES: To explore the determinant factors and prognostic significance of emergency department do-not-resuscitate (ED-DNR) orders for patients with spontaneous intracerebral hemorrhage (SICH). METHODS: Consecutive adult SICH patients treated in our ED from January 1, 2012 to December 31, 2016 were selected as the eligible cases from our hospital's stroke database. Patients' information was comprehensively reviewed from the database and medical and nursing charts...
June 10, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28621966/rosenbluth-separation-of-the-%C3%AF-0-electroproduction-cross-section-off-the-neutron
#3
M Mazouz, Z Ahmed, H Albataineh, K Allada, K A Aniol, V Bellini, M Benali, W Boeglin, P Bertin, M Brossard, A Camsonne, M Canan, S Chandavar, C Chen, J-P Chen, M Defurne, C W de Jager, R de Leo, C Desnault, A Deur, L El Fassi, R Ent, D Flay, M Friend, E Fuchey, S Frullani, F Garibaldi, D Gaskell, A Giusa, O Glamazdin, S Golge, J Gomez, O Hansen, D Higinbotham, T Holmstrom, T Horn, J Huang, M Huang, G M Huber, C E Hyde, S Iqbal, F Itard, Ho Kang, Hy Kang, A Kelleher, C Keppel, S Koirala, I Korover, J J LeRose, R Lindgren, E Long, M Magne, J Mammei, D J Margaziotis, P Markowitz, A Martí Jiménez-Argüello, F Meddi, D Meekins, R Michaels, M Mihovilovic, N Muangma, C Muñoz Camacho, P Nadel-Turonski, N Nuruzzaman, R Paremuzyan, A Puckett, V Punjabi, Y Qiang, A Rakhman, M N H Rashad, S Riordan, J Roche, G Russo, F Sabatié, K Saenboonruang, A Saha, B Sawatzky, L Selvy, A Shahinyan, S Sirca, P Solvignon, M L Sperduto, R Subedi, V Sulkosky, C Sutera, W A Tobias, G M Urciuoli, D Wang, B Wojtsekhowski, H Yao, Z Ye, L Zana, X Zhan, J Zhang, B Zhao, Z Zhao, X Zheng, P Zhu
We report the first longitudinal-transverse separation of the deeply virtual exclusive π^{0} electroproduction cross section off the neutron and coherent deuteron. The corresponding four structure functions dσ_{L}/dt, dσ_{T}/dt, dσ_{LT}/dt, and dσ_{TT}/dt are extracted as a function of the momentum transfer to the recoil system at Q^{2}=1.75  GeV^{2} and x_{B}=0.36. The ed→edπ^{0} cross sections are found compatible with the small values expected from theoretical models. The en→enπ^{0} cross sections show a dominance from the response to transversely polarized photons, and are in good agreement with calculations based on the transversity generalized parton distributions of the nucleon...
June 2, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28616981/bi-otf-3-mediated-intramolecular-olefinic-cyclization-synthesis-of-substituted-aryl-dihydronaphthalenes-and-indenes
#4
Chieh-Kai Chan, Nai-Chen Hsueh, Yu-Lin Tsai, Meng-Yang Chang
In this article, a facile two-step and one-pot synthetic route for the preparation of substituted aryl dihydronaphthalenes starting from 2-allylbenzaldehydes via Grignard 1,2-addition and Bi(OTf)3-catalyzed intramolecular olefinic cyclization has been developed. A five-membered ring indene skeleton is also prepared via olefin isomerization, 1,2-addition followed by cyclization. Some key structures are determined using single-crystal X-ray crystallography. A possible mechanism is presented herein.
June 21, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/28586627/validation-of-a-syndromic-case-definition-for-detecting-emergency-department-visits-potentially-related-to-marijuana
#5
Kathryn DeYoung, Yushiuan Chen, Robert Beum, Michele Askenazi, Cali Zimmerman, Arthur J Davidson
OBJECTIVES: Reliable methods are needed to monitor the public health impact of changing laws and perceptions about marijuana. Structured and free-text emergency department (ED) visit data offer an opportunity to monitor the impact of these changes in near-real time. Our objectives were to (1) generate and validate a syndromic case definition for ED visits potentially related to marijuana and (2) describe a method for doing so that was less resource intensive than traditional methods. METHODS: We developed a syndromic case definition for ED visits potentially related to marijuana, applied it to BioSense 2...
January 1, 2017: Public Health Reports
https://www.readbyqxmd.com/read/28577498/telomerase-reverse-transcriptase-genetically-modified-adipose-tissue-derived-stem-cells-improves-erectile-dysfunction-by-inhibiting-oxidative-stress-and-enhancing-proliferation-in-rat-model
#6
Xiao-Jun Wu, Wen-Hao Shen, Peng He, Xiao-Zhou Zhou, Yi Zhi, Qiang Dai, Zhi-Wen Chen, Zhan-Song Zhou
Erectile dysfunction (ED) is considered to be incapable of obtaining or/and keeping a sufficient erection function to receive the satisfactory during the sexual intercourse. This study aims to investigate the effects of telomerase reverse transcriptase (hTERT) modified adipose tissue derived stem cells (ADSCs) autologously injected into cavernosa of the ED rats on erectile function. The ADSCs were isolated form the rat subcutaneous adipose tissue sample, and identified by examining the CD29 and CD44 molecule...
May 31, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28559039/geographic-variation-in-use-of-ambulance-transport-to-the-emergency-department
#7
Amresh D Hanchate, Michael K Paasche-Orlow, K Sophia Dyer, William E Baker, Chen Feng, James Feldman
STUDY OBJECTIVE: Evidence on variability in emergency medical services use is limited. We obtain national evidence on geographic variation in the use of ambulance transport to the emergency department (ED) among Medicare enrollees and assess the role of health status, socioeconomic status, and provider availability. METHODS: We used 2010 Medicare claims data for a random sample of 999,999 enrollees aged 66 years and older, and identified ambulance transport and ED use...
May 27, 2017: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/28553762/evaluation-of-serum-neutrophil-gelatinase-associated-lipocalin-in-predicting-acute-kidney-injury-in-critically-ill-patients
#8
Chen-Chen Hang, Jun Yang, Shuo Wang, Chun-Sheng Li, Zi-Ren Tang
Objective This investigation evaluated the real-time point-of-care testing (RT-POCT) of neutrophil gelatinase-associated lipocalin (NGAL) for detecting acute kidney injury (AKI) and prognosis of critically ill patients. Methods A total of 249 critically ill patients in the emergency department (ED), who were diagnosed with acute decompensated heart failure, sepsis or diabetic ketoacidosis were enrolled in this study. All enrolled patients were followed up for 28 days or to death and the mortalities were recorded...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28550123/essential-role-for-histone-deacetylase-11-hdac11-in-neutrophil-biology
#9
Eva Sahakian, Jie Chen, John J Powers, Xianghong Chen, Kamira Maharaj, Susan L Deng, Maritza Lienlaf, Hong Wei Wang, Fengdong Cheng, Andressa L Sodré, Allison Distler, Limin Xing, Patricio Perez-Villarroel, Sheng Wei, Alejandro Villagra, Ed Seto, Eduardo M Sotomayor, Pedro Horna, Javier Pinilla-Ibarz
Epigenetic changes in chromatin structure have been recently associated with the deregulated expression of critical genes in normal and malignant processes. HDAC11, the newest member of the HDAC family of enzymes, functions as a negative regulator of IL-10 expression in APCs, as previously described by our lab. However, at the present time, its role in other hematopoietic cells, specifically in neutrophils, has not been fully explored. In this report, for the first time, we present a novel physiologic role for HDAC11 as a multifaceted regulator of neutrophils...
May 26, 2017: Journal of Leukocyte Biology
https://www.readbyqxmd.com/read/28522875/serum-uric-acid-is-associated-with-erectile-dysfunction-a-population-based-cross-sectional-study-in-chinese-men
#10
Fengbin Gao, Boren Jiang, Zhen Cang, Ningjian Wang, Bing Han, Qin Li, Yi Chen, Yingchao Chen, Fangzhen Xia, Hualing Zhai, Chi Chen, Meng Lu, Ying Meng, Yingli Lu, Zhoujun Shen
The role that serum uric acid (UA) plays in the pathophysiological development of erectile dysfunction (ED) is controversial. We aimed to screen the factors related with ED, and to examine the association between serum UA and ED. Our data were derived from a cross-sectional Survey on Prevalence in East China for Metabolic Diseases and Risk Factors study in 2014-2015. Questionnaire of International Index of Erectile Dysfunction-5 was used for assessment of ED. Data were collected in three general communities respectively...
May 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28511298/-influence-of-aluminum-chloride-exposure-on-embryonic-development-of-zebrafish-and-neurobehavior-of-juvenile-fish
#11
J P Chen, N Shang, K H He, L Zhang, Q Niu, Q L Zhang
Objective: To investigate the influence of aluminum chloride (AlCl(3)) solution on the embryon-ic development of zebrafish and neurobehavior of juvenile fish. Methods: The embryos of zebrafishat 6 hours after fertilization were exposed to AlCl(3) solution at a concentration of 0, 55.0, 60.5, 66.6, 73.5, 80.5, or 100.0 mg/L, and embryonic hatching rates at 48 and 72 hours after fertilization were calculated. The embryos of zebrafishat 6 hours after fertilization were exposed to AlCl(3) solution at a concentration of 0, 60...
March 20, 2017: Chinese Journal of Industrial Hygiene and Occupational Diseases
https://www.readbyqxmd.com/read/28494994/predicting-return-visits-to-the-emergency-department-for-pediatric-patients-applying-supervised-learning-techniques-to-the-taiwan-national-health-insurance-research-database
#12
Ya-Han Hu, Chun-Tien Tai, Solomon Chih-Cheng Chen, Hai-Wei Lee, Sheng-Feng Sung
BACKGROUND AND OBJECTIVE: Return visits (RVs) to the emergency department (ED) consume medical resources and may represent a patient safety issue. The occurrence of unexpected RVs is considered a performance indicator for ED care quality. Because children are susceptible to medical errors and utilize considerable ED resources, knowing the factors that affect RVs in pediatric patients helps improve the quality of pediatric emergency care. METHODS: We collected data on visits made by patients aged ≤18years to EDs from the National Health Insurance Research Database...
June 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28489813/implementing-a-novel-model-for-hospice-and-palliative-care-in-the-emergency-department-an-experience-from-a-tertiary-medical-center-in-taiwan
#13
Tzu-Chieh Weng, Ya-Chun Yang, Ping-Jen Chen, Wen-Fu Kuo, Wei-Lin Wang, Ya-Ting Ke, Chien-Chin Hsu, Kao-Chang Lin, Chien-Cheng Huang, Hung-Jung Lin
Hospice and palliative care has been recognized as an essential part of emergency medicine; however, there is no consensus on the optimal model for the delivery of hospice and palliative care in the emergency department (ED). Therefore, we conducted a novel implementation in a tertiary medical center in Taiwan. In the preintervention period, we recruited a specialist for hospice and palliative medicine in the ED to lead our intervention. In the early stage of the intervention, starting on July 1, 2014, we encouraged and funded ED physicians and nurses to receive training for hospice and palliative medicine and residents of emergency medicine to rotate to the hospice ward...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28487095/workplace-violence-against-emergency-nurses-in-taiwan-a-phenomenographic-study
#14
Chin-Yen Han, Chun-Chih Lin, Alan Barnard, Ya-Chu Hsiao, Suzanne Goopy, Li-Chin Chen
BACKGROUND: Workplace violence (WPV) is a serious problem in health care in Taiwan, as it is worldwide. Among all nursing staff, emergency department (ED) nurses are at the highest risk of WPV; yet, little attention has been paid to nurses as WPV victims. PURPOSE: The purpose of the study was to understand ED nurses' WPV experiences and perspectives. METHODS: An interpretive qualitative phenomenographic design was used to answer the following research question: what are the qualitatively different ways in which nurses in Taiwan experience WPV in the ED? Thirty ED nurses who identified as experienced with WPV were interviewed, and phenomenographic analysis was used to assess the data...
April 13, 2017: Nursing Outlook
https://www.readbyqxmd.com/read/28485313/clinical-characteristics-and-current-interventions-in-shock-patients-in-chinese-emergency-departments-a-multicenter-prospective-cohort-study
#15
Shu-Bin Guo, Yun-Xia Chen, Xue-Zhong Yu
BACKGROUND: Shock is a life-threatening condition in emergency departments (EDs) and is associated with a high mortality; however, its clinical characteristics and current interventions in China are seldom reported. This study investigated the clinical characteristics and current interventions of shock patients in Chinese EDs. METHODS: This multicenter prospective cohort study was conducted in the EDs of 33 academic hospitals in 16 Chinese provinces. Adult shock patients were enrolled from December 2013 to April 2014...
May 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28473709/a-new-strategy-for-deleting-animal-drugs-from-traditional-chinese-medicines-based-on-modified-yimusake-formula
#16
Jinghui Wang, Yan Li, Yinfeng Yang, Xuetong Chen, Jian Du, Qiusheng Zheng, Zongsuo Liang, Yonghua Wang
Traditional Chinese medicine (TCM), such as Uyghur Medicine (UM) has been used in clinical treatment for many years. TCM is featured as multiple targets and complex mechanisms of action, which is normally a combination of medicinal herbs and sometimes even contains certain rare animal medicinal ingredients. A question arises as to whether these animal materials can be removed replaced from TCM applications due to their valuable rare resources or animal ethics. Here, we select a classical UM Yimusake formula, which contains 3 animal drugs and other 8 herbs, and has got wealthy experience and remarkable achievements in treating erectile dysfunction (ED) in China...
May 4, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28458756/infected-aortic-and-iliac-aneurysms-clinical-manifestations-in-the-emergency-departments-of-two-hospitals-in-southern-taiwan-china
#17
Chang-Chih Tsai, Chien-Chin Hsu, Kuo-Tai Chen
BACKGROUND: Accurate diagnosis of infected aortic and iliac aneurysms is often delayed, hampering timely treatment and potentially resulting in a fatal consequence. The aim of this study was to discover useful clinical features that can help physicians to identify these patients. METHODS: We reviewed the discharge notes from two hospitals and identified all patients who had a diagnosis of infected aneurysms of the thoracoabdominal aorta and iliac arteries between July 2009 and December 2013...
2017: World Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28436762/use-of-dietary-vitamin-supplements-and-risk-of-thyroid-cancer-a-population-based-case-control-study-in-connecticut
#18
Christopher Kim, Huang Huang, Nan Zhao, Catherine C Lerro, Min Dai, Yingtai Chen, Ni Li, Shuangge Ma, Robert Udelsman, Yawei Zhang
Certain dietary supplements have been reported to increase the risk of some cancers. Over half of the US population regularly uses dietary supplements. Thyroid cancer incidence has increased over the past several decades. However, few studies have investigated the association between dietary supplements and thyroid cancer. Thus, it is essential to clarify any association between dietary supplements and risk of thyroid cancer. MATERIALS AND METHODS: A population-based case-control study in Connecticut was conducted during 2010-2011 among 462 histologically confi rmed incident thyroid cancer cases and 498 population-based controls...
April 24, 2017: International Journal for Vitamin and Nutrition Research. Journal International de Vitaminologie et de Nutrition
https://www.readbyqxmd.com/read/28434082/senior-general-surgery-residents-can-be-trained-to-perform-focused-assessment-with-sonography-for-trauma-patients-accurately
#19
Sheng-Der Hsu, Cheng-Jueng Chen, De-Chuan Chan, Jyh-Cherng Yu
PURPOSES: Researchers studying trauma have found that physicians are able to perform a focused assessment with sonography for trauma (FAST) with minimal training and achieve ideal accuracy. However, there are currently no consensus or standard guidelines regarding the performance of this assessment. The aim of our study was to clarify the value of FAST performed by well-qualified senior general surgery residents in cases of suspected blunt abdominal trauma, which presents an important diagnostic problem in emergency departments...
April 22, 2017: Surgery Today
https://www.readbyqxmd.com/read/28430095/window-of-opportunity-for-new-disease-surveillance-developing-keyword-lists-for-monitoring-mental-health-and-injury-through-syndromic-surveillance
#20
Ursula Lauper, Jian-Hua Chen, Shao Lin
Studies have documented the impact that hurricanes have on mental health and injury rates before, during, and after the event. Since timely tracking of these disease patterns is crucial to disaster planning, response, and recovery, syndromic surveillance keyword filters were developed by the New York State Department of Health to study the short- and long-term impacts of Hurricane Sandy. Emergency department syndromic surveillance is recognized as a valuable tool for informing public health activities during and immediately following a disaster...
April 2017: Disaster Medicine and Public Health Preparedness
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