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https://www.readbyqxmd.com/read/29180283/current-readings-on-surgery-for-the-neonate-with-hypoplastic-aortic-arch
#1
Bari Murtuza, Bahaaldin Alsoufi
Aortic arch hypoplasia is commonly present in neonates born with ductal-dependant coarctation of the aorta. The ideal surgical repair of neonates with proximal arch hypoplasia continues to be debated. Controversy exists about the fate of the hypoplastic proximal aortic arch following surgical repair and whether that will eventually grow to normal size upon relief of the distal obstruction or will persist as a residual lesion that can affect long-term outlook of those patients. There is new evidence that residual proximal arch hypoplasia and the shape of the reconstructed arch both have an important impact on vascular remodelling and subsequent development of hypertension...
November 24, 2017: Seminars in Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28942973/statistical-versus-clinical-significance
#2
EDITORIAL
Bahaaldin Alsoufi
No abstract text is available yet for this article.
September 8, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28780182/lost-in-translation
#3
EDITORIAL
Bahaaldin Alsoufi
No abstract text is available yet for this article.
July 19, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28738579/compositional-engineering-of-vopcpho-tio2-nano-composite-to-reduce-the-absolute-threshold-value-of-humidity-sensors
#4
Mohamad Izzat Azmer, Fakhra Aziz, Zubair Ahmad, Ehsan Raza, Mansoor Ani Najeeb, Noshin Fatima, Tahani M Bawazeer, Mohammad S Alsoufi, R A Shakoor, Khaulah Sulaiman
This research work demonstrates compositional engineering of an organic-inorganic hybrid nano-composites for modifying absolute threshold of humidity sensors. Vanadyl-2,9,16,23-tetraphenoxy-29H,31H-phthalocyanine (VOPcPhO), an organic semiconductor, doped with Titanium-dioxide nanoparticles (TiO2 NPs) has been employed to fabricate humidity sensors. The morphology of the VOPcPhO:TiO2 nano-composite films has been analyzed by atomic force microscopy (AFM) and field emission scanning electron microscopy (FESEM)...
November 1, 2017: Talanta
https://www.readbyqxmd.com/read/28709664/current-results-of-single-ventricle-palliation-of-patients-with-double-inlet-left-ventricle
#5
Bahaaldin Alsoufi, Courtney McCracken, Kirk Kanter, Subhadra Shashidharan, Brian Kogon
BACKGROUND: Double inlet left ventricle (DILV) is a heterogeneous single ventricle anomaly in which initial presentation, and consequently, timing and palliation mode vary based on morphology and degree of pulmonary or systemic outflow obstruction. Very few reports, mostly old, focused on palliation outcomes of DILV. We report current-era results and examine whether morphologic and subsequently surgical factors influence survival. METHODS: Fifty-eight infants with DILV underwent single ventricle palliation...
July 11, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28669502/the-impact-of-22q11-2-deletion-syndrome-on-surgical-repair-outcomes-of-conotruncal-cardiac-anomalies
#6
COMPARATIVE STUDY
Bahaaldin Alsoufi, Courtney McCracken, Subhadra Shashidharan, Shriprasad Deshpande, Kirk Kanter, Brian Kogon
BACKGROUND: We aim to describe the impact of 22q11.2 deletion syndrome (22q11DS) on clinical characteristics, postoperative course, and early and late outcomes of neonates undergoing surgery for conotruncal anomalies. METHODS: A retrospective review was performed (2002 to 2012) of 224 neonates who underwent surgery for interrupted aortic arch (n = 67), truncus arteriosus (n = 85), or ductal-dependent pulmonary atresia and ventricular septal defect (n = 72). Patients were divided into three groups: group 1, n = 119, no genetic syndrome; group 2, n = 64, 22q11DS; and group 3, n = 41, other genetic syndrome...
November 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28412117/bigger-is-not-always-better
#7
EDITORIAL
Bahaaldin Alsoufi
No abstract text is available yet for this article.
March 18, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28329454/adult-congenital-cardiac-care
#8
MULTICENTER STUDY
Brian E Kogon, Kati Miller, Paula Miller, Bahaaldin Alsoufi, Joshua M Rosenblum
BACKGROUND: The Adult Congenital Heart Association (ACHA) is dedicated to supporting patients with congenital heart disease. To guide patients to qualified providers and programs, it maintains a publicly accessible directory of dedicated adult congenital cardiac programs. We analyzed the directory in 2006 and 2015, aiming to evaluate the growth of the directory as a whole and to evaluate the growth of individual programs within the directory. We also hope this raises awareness of the growing opportunities that exist in adult congenital cardiology and cardiac surgery...
March 2017: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/28007061/the-evolution-of-an-adult-congenital-heart-surgery-program-the-emory-system
#9
REVIEW
Brian Kogon, Joshua Rosenblum, Bahaaldin Alsoufi, Subhadra Shashidharan, Wendy Book
The Emory Adult Congenital Heart (Emory University, Atlanta, GA) program was founded in 2001. In 2004, the surgical component transitioned from a pediatric facility to an adult facility. The aim of this article is characterize the program as a whole, outline changes in the program, and discuss the challenges of the transition process. Between 2001 and 2015, changes in program structure and personnel were evaluated. There has been significant growth of the program between 2001 and 2015. There are currently 19 half-day clinics per week, with 2,700 clinic visits per year...
January 2017: Seminars in Thoracic and Cardiovascular Surgery. Pediatric Cardiac Surgery Annual
https://www.readbyqxmd.com/read/27964979/thinking-fast-and-slow
#10
EDITORIAL
Bahaaldin Alsoufi
No abstract text is available yet for this article.
March 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27645915/a-30-year-experience-with-mixed-type-total-anomalous-pulmonary-venous-connection-a-word-of-caution
#11
Brian Kogon, Jan Fernandez, Subhadra Shashidharan, Kirk Kanter, Bahaaldin Alsoufi
BACKGROUND: Patients with total anomalous pulmonary venous connection can be problematic, particularly those with mixed-type pathology. We aimed to describe a cohort of patients with mixed-type anomalous drainage, highlighting the treatment challenges, and identifying risk factors for poor outcome. METHODS: We reviewed the clinical records of patients who underwent repair for mixed-type total anomalous pulmonary venous connection between 1986 and 2015. RESULTS: A total of 19 patients were identified...
July 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/27592600/palliation-outcomes-of-neonates-born-with-single-ventricle-anomalies-associated-with-aortic-arch-obstruction
#12
Bahaaldin Alsoufi, Courtney McCracken, Subhadra Shashidharan, Brian Kogon, William Border, Kirk Kanter
BACKGROUND: The two most common surgical strategies for the treatment of neonates born with single-ventricle anomalies associated with aortic arch obstruction are the Norwood operation and pulmonary artery banding plus coarctation repair (PAB+COA). We reviewed characteristics and outcomes of neonates who underwent those two surgical strategies at our institution. METHODS: Between 2002 and 2012, 94 neonates with a single ventricle and aortic arch obstruction (excluding hypoplastic left heart syndrome) underwent Norwood (n = 65) or PAB+COA (n = 29)...
February 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27568147/the-effect-of-noncardiac-and-genetic-abnormalities-on-outcomes-following-neonatal-congenital-heart-surgery
#13
Bahaaldin Alsoufi
No abstract text is available yet for this article.
2016: Seminars in Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27568146/the-effect-of-noncardiac-and-genetic-abnormalities-on-outcomes-following-neonatal-congenital-heart-surgery
#14
Bahaaldin Alsoufi, Scott Gillespie, William T Mahle, Shriprasad Deshpande, Brian Kogon, Kevin Maher, Kirk Kanter
Significant noncardiac and genetic abnormalities (NC and GA) are common in neonates with congenital heart defects. We sought to examine current-era effect of those abnormalities on early and late outcomes following cardiac surgery. The method from 2002-2012, 1538 neonates underwent repair (n = 860, 56%) or palliation (n = 678, 44%) of congenital heart defects. Regression models examined the effect of NC and GA on operative results, resource utilization, and late outcomes. Neonates with NC and GA (n = 312, 20%) had higher incidence of prematurity (21% vs 13%; P < 0...
2016: Seminars in Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27530641/extracorporeal-membrane-oxygenator-support-in-infants-with-systemic-pulmonary-shunts
#15
Phil Botha, Shriprasad R Deshpande, Michael Wolf, Micheal Heard, Bahaaldin Alsoufi, Brian Kogon, Kirk Kanter
BACKGROUND: Management of a patent systemic-pulmonary (SP) shunt and the resulting runoff during extracorporeal membrane oxygenation (ECMO) varies among institutions. We have used a strategy of increased flow without surgical reduction of the shunt diameter, and here report our results with this strategy. METHODS: In this database review of 169 successive veno-arterial ECMO runs performed between 2002 and 2013 in infants and neonates, ECMO flow, time to achieve lactate clearance, normal pH, and negative fluid balance were compared in patients with shunts and those without shunts...
September 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27345094/the-impact-of-dominant-ventricle-morphology-on-palliation-outcomes-of-single-ventricle-anomalies
#16
Bahaaldin Alsoufi, Scott Gillespie, Dennis Kim, Subhadra Shashidharan, Kirk Kanter, Kevin Maher, Brian Kogon
BACKGROUND: Differences in right ventricle and tricuspid valve structure compared with left ventricle and mitral valve structure make them less equipped to support the systemic circulation long term, with subsequent systemic right ventricle failure. We examined the effect of dominant ventricle morphology on single ventricle palliation outcomes. METHODS: We grouped 530 neonates who underwent first-stage palliation into two groups based on dominant ventricle morphology: right dominant ventricle (RV group; n = 302, 57%) and left dominant ventricle or functional single ventricle with two well-formed ventricles (LV group; n = 228, 43%)...
August 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27325496/is-there-a-limit-to-how-far-we-should-push-the-envelope-in-pediatric-cardiac-surgery
#17
EDITORIAL
Bahaaldin Alsoufi
No abstract text is available yet for this article.
September 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27207392/current-outcomes-of-surgical-management-of%C3%A2-aortopulmonary-window-and-associated-cardiac-lesions
#18
Bahaaldin Alsoufi, Brian Schlosser, Courtney McCracken, Brian Kogon, Kirk Kanter, William Border, Ritu Sachdeva
BACKGROUND: Aortopulmonary window (APW) is a rare congenital defect that is often associated with other cardiac lesions. We analyzed our operative strategy to determine whether this had any relationship with outcomes. METHODS: Early and late outcomes of 40 children who underwent APW repair at our institution during a 20-year period (1994 to 2013) were analyzed. RESULTS: Median age at time of the operation was 22 days (interquartile range, 9 to 63 days), and median weight was 3...
August 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27174514/outcomes-of-neonates-requiring-prolonged-stay-in-the-intensive-care-unit-after-surgical-repair-of-congenital-heart-disease
#19
Makoto Mori, Courtney McCracken, Kevin Maher, Brian Kogon, William Mahle, Kirk Kanter, Bahaaldin Alsoufi
OBJECTIVE: After neonatal cardiac surgery, a number of patients need a prolonged stay in the intensive care unit (ICU). Those patients require tremendous resources and strain the capacity of cardiac units. To date, little knowledge of early and late survival for this challenging population exists. METHODS: From 2002 to 2012, 108 neonates required a postoperative ICU stay >30 days. Multivariable regression analyses examined factors associated with hospital death and late survival...
September 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27151913/age-dependent-effect-of-pediatric-cardiac-progenitor-cells-after-juvenile-heart-failure
#20
Udit Agarwal, Amanda W Smith, Kristin M French, Archana V Boopathy, Alex George, David Trac, Milton E Brown, Ming Shen, Rong Jiang, Janet D Fernandez, Brian E Kogon, Kirk R Kanter, Baahaldin Alsoufi, Mary B Wagner, Manu O Platt, Michael E Davis
UNLABELLED: Children with congenital heart diseases have increased morbidity and mortality, despite various surgical treatments, therefore warranting better treatment strategies. Here we investigate the role of age of human pediatric cardiac progenitor cells (hCPCs) on ventricular remodeling in a model of juvenile heart failure. hCPCs isolated from children undergoing reconstructive surgeries were divided into 3 groups based on age: neonate (1 day to 1 month), infant (1 month to 1 year), and child (1 to 5 years)...
July 2016: Stem Cells Translational Medicine
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