keyword
MENU ▼
Read by QxMD icon Read
search

Auditory gap detection

keyword
https://www.readbyqxmd.com/read/28214516/saturation-of-long-term-potentiation-in-the-dorsal-cochlear-nucleus-and-its-pharmacological-reversal-in-an-experimental-model-of-tinnitus
#1
Thomas Tagoe, Daniel Deeping, Martine Hamann
Animal models have demonstrated that tinnitus is a pathology of dysfunctional excitability in the central auditory system, in particular in the dorsal cochlear nucleus (DCN) of the brainstem. We used a murine model and studied whether acoustic over-exposure leading to hearing loss and tinnitus, affects long-term potentiation (LTP) at DCN multisensory synapses. Whole cell and field potential recordings were used to study the effects on release probability and synaptic plasticity, respectively in brainstem slices...
February 15, 2017: Experimental Neurology
https://www.readbyqxmd.com/read/28185661/age-related-deficits-in-auditory-temporal-processing-unique-contributions-of-neural-dyssynchrony-and-slowed-neuronal-processing
#2
Kelly C Harris, Judy R Dubno
This study was guided by the hypothesis that the aging central nervous system progressively loses its ability to process rapid acoustic changes that are important for speech recognition. Specifically, we hypothesized that age-related deficits in neural synchrony and neuronal oscillatory activity occur independently in older adults and disrupt auditory temporal processing. Neural synchrony is largely dependent on phase locking within the central auditory pathway, beginning at the auditory nerve. In contrast, the resonance characteristics of oscillatory activity are dependent on the integrity and structure of long range cortical connections...
January 16, 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/28097439/modeling-responses-in-the-superior-paraolivary-nucleus-implications-for-forward-masking-in-the-inferior-colliculus
#3
Nima Salimi, Muhammad S A Zilany, Laurel H Carney
A phenomenological model of the responses of neurons in the superior paraolivary nucleus (SPON) of the rodent is presented in this study. Pure tones at the characteristic frequency (CF) and broadband noise stimuli evoke offset-type responses in these neurons. SPON neurons also phase-lock to the envelope of sinusoidally amplitude-modulated (SAM) stimuli for a range of modulation frequencies. Model SPON neuron received inhibitory input that was relayed by the ipsilateral medial nucleus of the trapezoid body from the contralateral model ventral cochlear nucleus neuron...
January 17, 2017: Journal of the Association for Research in Otolaryngology: JARO
https://www.readbyqxmd.com/read/28054915/auditory-processing-disorder-as-the-sole-manifestation-of-a-cerebellopontine-and-internal-auditory-canal-lesion
#4
Vasiliki Vivian Iliadou, Nikos Eleftheriadis
BACKGROUND: Clinical importance of auditory processing disorder (APD) testing is often overlooked and regarded with skepticism given the challenging interpretation of results and the current growing debate of its nature and clinical entity. PURPOSE: Presentation of this case is highly educational as APD is the single clinical manifestation of a large cerebellopontine and internal auditory canal lesion. RESEARCH DESIGN: A case report. DATA COLLECTION AND ANALYSIS: The patient underwent a standard audiological evaluation with normal results...
January 2017: Journal of the American Academy of Audiology
https://www.readbyqxmd.com/read/28050647/deleting-the-hcn1-subunit-of-hyperpolarization-activated-ion-channels-in-mice-impairs-acoustic-startle-reflexes-gap-detection-and-spatial-localization
#5
James R Ison, Paul D Allen, Donata Oertel
It has been proposed that the high temporal and spatial acuities of human listeners and animals tested in the hearing laboratory depend in part on the short time constants of auditory neurons that are able to preserve or sharpen the information conveyed in the timing of firing of auditory nerve fibers. We tested this hypothesis in a series of in vivo experiments, based on previous in vitro experiments showing that neuronal time constants are raised in brainstem slices when HCN1 channels are blocked or in slices obtained from Hcn1 (-/-) null mutant mice...
January 3, 2017: Journal of the Association for Research in Otolaryngology: JARO
https://www.readbyqxmd.com/read/28024919/effect-of-gap-detection-threshold-on-consistency-of-speech-in-children-with-speech-sound-disorder
#6
Fateme Sayyahi, Zahra Soleymani, Mohammad Akbari, Mahmood Bijankhan, Behrooz Dolatshahi
BACKGROUND AND AIMS: The present study examined the relationship between gap detection threshold and speech error consistency in children with speech sound disorder. METHODS AND PROCEDURES: The participants were children five to six years of age who were categorized into three groups of typical speech, consistent speech disorder (CSD) and inconsistent speech disorder (ISD).The phonetic gap detection threshold test was used for this study, which is a valid test comprised six syllables with inter-stimulus intervals between 20-300ms...
December 23, 2016: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/27893606/cochlear-brainstem-and-psychophysical-responses-show-spectrotemporal-tradeoff-in-human-auditory-processing
#7
Gavin M Bidelman, Shaum P Bhagat
Auditory filter theory posits a tradeoff in time-frequency analysis: high temporal precision is achievable only at the expense of poorer frequency resolution and vice versa. Here, we examined the hierarchy of brain mechanisms of these spectrotemporal tradeoffs through a series of physiological and behavioral measures aimed to tap temporal and spectral acuity at different levels of the auditory neuroaxis (cochlea→brainstem→percept). Cochlear and behavioral frequency selectivity was measured by stimulus-frequency otoacoustic emissions (SFOAE) and psychophysical tuning curves; temporal acuity was measured physiologically and behaviorally by paired click recovery of auditory brainstem responses (ABRs) and gap detection thresholds (GDTs), respectively...
January 1, 2017: Neuroreport
https://www.readbyqxmd.com/read/27885514/speech-evoked-auditory-brainstem-response-and-gap-detection-threshold-in-middle-aged-individual
#8
Himanshu Kumar Sanju, Vaishnavi Bohra, Sujeet Kumar Sinha
This study aimed at characterizing the gap detection threshold (GDT) and speech evoked ABR (SABR) in younger and middle-aged individuals. Two groups of subjects were participated in the study which includes 15 young adults in the age range of 15-25 years and 15 middle-aged individuals in the age range of 40-60 years. SABR with stimulus/da/of 40 ms and GDT were investigated on both groups. For SABR, Mann-Whitney U test revealed that ageing has significantly adverse effect on the encoding of F1 and F2 at brainstem level...
November 24, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27869513/adverse-effects-of-pesticides-on-central-auditory-functions-in-tobacco-growers
#9
França Denise Maria Vaz Romano, Adriana Bender Moreira Lacerda, Diolen Lobato, Angela Ribas, Karin Ziliotto Dias, Tony Leroux, Adrian Fuente
OBJECTIVE: To investigate the effects of exposure to pesticides on the central auditory functions (CAF) of Brazilian tobacco growers. DESIGN: This was a cross-sectional study carried out between 2010 and 2012. Participants were evaluated with two behavioural procedures to investigate CAF, the random gap detection test (RGDT) and the dichotic digit test in Portuguese (DDT). STUDY SAMPLE: A total of 22 growers exposed to pesticides (study group) and 21 subjects who were not exposed to pesticides (control group) were selected...
November 21, 2016: International Journal of Audiology
https://www.readbyqxmd.com/read/27862478/reductions-in-cortical-alpha-activity-enhancements-in-neural-responses-and-impaired-gap-detection-caused-by-sodium-salicylate-in-awake-guinea-pigs
#10
Joel I Berger, Ben Coomber, Mark N Wallace, Alan R Palmer
Tinnitus chronically affects between 10-15% of the population but, despite its prevalence, the underlying mechanisms are still not properly understood. One experimental model involves administration of high doses of sodium salicylate, as this is known to reliably induce tinnitus in both humans and animals. Guinea pigs were implanted with chronic electrocorticography (ECoG) electrode arrays, with silver-ball electrodes placed on the dura over left and right auditory cortex. Two more electrodes were positioned over the cerebellum to monitor auditory brainstem responses (ABRs)...
November 12, 2016: European Journal of Neuroscience
https://www.readbyqxmd.com/read/27819648/evaluation-of-the-relationship-between-the-air-bone-gap-and-prolonged-abr-latencies-in-mixed-type-hearing-loss
#11
Ömer Faruk Birkent, Turgut Karlıdağ, Figen Başar, Şinasi Yalçın, İrfan Kaygusuz, Erol Keleş, Abdulvahap Akyiğit
OBJECTIVE: The aim of this study was to determine the air-bone gaps in adults with mixed-type hearing loss using air-conduction auditory brainstem response (ABR) latencies. MATERIALS AND METHODS: Thirty adults with mixed-type hearing loss (study group) and 30 adults with normal hearing (control group) were included in this study. Before performing ABR measurements, ear, nose, and throat examinations, pure tone audiometry, speech audiometry, acoustic immittance audiometry, and transient evoked autoacoustic emission testing were performed for all participants...
November 7, 2016: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/27746835/auditory-temporal-resolution-in-individuals-with-diabetes-mellitus-type-2
#12
Rajkishor Mishra, Himanshu Kumar Sanju, Prawin Kumar
Introduction "Diabetes mellitus is a group of metabolic disorders characterized by elevated blood sugar and abnormalities in insulin secretion and action" (American Diabetes Association). Previous literature has reported connection between diabetes mellitus and hearing impairment. There is a dearth of literature on auditory temporal resolution ability in individuals with diabetes mellitus type 2. Objective The main objective of the present study was to assess auditory temporal resolution ability through GDT (Gap Detection Threshold) in individuals with diabetes mellitus type 2 with high frequency hearing loss...
October 2016: International Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/27746832/temporal-resolution-and-active-auditory-discrimination-skill-in-vocal-musicians
#13
Prawin Kumar, Himanshu Kumar Sanju, J Nikhil
Introduction Enhanced auditory perception in musicians is likely to result from auditory perceptual learning during several years of training and practice. Many studies have focused on biological processing of auditory stimuli among musicians. However, there is a lack of literature on temporal resolution and active auditory discrimination skills in vocal musicians. Objective The aim of the present study is to assess temporal resolution and active auditory discrimination skill in vocal musicians. Method The study participants included 15 vocal musicians with a minimum professional experience of 5 years of music exposure, within the age range of 20 to 30 years old, as the experimental group, while 15 age-matched non-musicians served as the control group...
October 2016: International Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/27608143/anatomical-functional-and-quality-of-life-results-for-mastoid-and-epitympanic-obliteration-with-bioactive-glass-s53p4-a-prospective-clinical-study
#14
D Bernardeschi, N Pyatigorskaya, F Y Russo, D De Seta, G Corallo, E Ferrary, Y Nguyen, O Sterkers
OBJECTIVE: To analyse the anatomical, functional and quality-of-life results when using bioactive glass in mastoid and epitympanic obliteration. DESIGN: Prospective clinical study. SETTING: Tertiary referral centre. PARTICIPANTS: Forty-one cases (39 patients) operated between May 2013 and January 2015. MAIN OUTCOME MEASURES: Anatomical results were evaluated by otomicroscopy 1 year after surgery and using imaging to detect residual disease...
September 8, 2016: Clinical Otolaryngology
https://www.readbyqxmd.com/read/27598040/the-effect-of-distraction-on-change-detection-in-crowded-acoustic-scenes
#15
Theofilos Petsas, Jemma Harrison, Makio Kashino, Shigeto Furukawa, Maria Chait
In this series of behavioural experiments we investigated the effect of distraction on the maintenance of acoustic scene information in short-term memory. Stimuli are artificial acoustic 'scenes' composed of several (up to twelve) concurrent tone-pip streams ('sources'). A gap (1000 ms) is inserted partway through the 'scene'; Changes in the form of an appearance of a new source or disappearance of an existing source, occur after the gap in 50% of the trials. Listeners were instructed to monitor the unfolding 'soundscapes' for these events...
September 2, 2016: Hearing Research
https://www.readbyqxmd.com/read/27587925/the-effect-of-short-term-auditory-training-on-speech-in-noise-perception-and-cortical-auditory-evoked-potentials-in-adults-with-cochlear-implants
#16
Nathan Barlow, Suzanne C Purdy, Mridula Sharma, Ellen Giles, Vijay Narne
This study investigated whether a short intensive psychophysical auditory training program is associated with speech perception benefits and changes in cortical auditory evoked potentials (CAEPs) in adult cochlear implant (CI) users. Ten adult implant recipients trained approximately 7 hours on psychophysical tasks (Gap-in-Noise Detection, Frequency Discrimination, Spectral Rippled Noise [SRN], Iterated Rippled Noise, Temporal Modulation). Speech performance was assessed before and after training using Lexical Neighborhood Test (LNT) words in quiet and in eight-speaker babble...
February 2016: Seminars in Hearing
https://www.readbyqxmd.com/read/27582696/glast-deficiency-in-mice-exacerbates-gap-detection-deficits-in-a-model-of-salicylate-induced-tinnitus
#17
Hong Yu, Kim Vikhe Patil, Chul Han, Brian Fabella, Barbara Canlon, Shinichi Someya, Christopher R Cederroth
Gap detection or gap pre-pulse inhibition of the acoustic startle (GPIAS) has been successfully used in rat and guinea pig models of tinnitus, yet this system has been proven to have low efficacy in CBA mice, with low basal GPIAS and subtle tinnitus-like effects. Here, we tested five mouse strains (CBA, BalbC, CD-1, C57BL/6 and 129sv) for pre-pulse inhibition (PPI) and gap detection with varying interstimulus intervals (ISI) and found that mice from a CBA genetic background had the poorest capacities of suppressing the startle response in the presence of a pre-pulse or a gap...
2016: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/27475211/rapid-auditory-learning-of-temporal-gap-detection
#18
Srikanta K Mishra, Manasa R Panda
The rapid initial phase of training-induced improvement has been shown to reflect a genuine sensory change in perception. Several features of early and rapid learning, such as generalization and stability, remain to be characterized. The present study demonstrated that learning effects from brief training on a temporal gap detection task using spectrally similar narrowband noise markers defining the gap (within-channel task), transfer across ears, however, not across spectrally dissimilar markers (between-channel task)...
July 2016: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/27380177/the-coda-of-the-transient-response-in-a-sensitive-cochlea-a-computational-modeling-study
#19
Yizeng Li, Karl Grosh
In a sensitive cochlea, the basilar membrane response to transient excitation of any kind-normal acoustic or artificial intracochlear excitation-consists of not only a primary impulse but also a coda of delayed secondary responses with varying amplitudes but similar spectral content around the characteristic frequency of the measurement location. The coda, sometimes referred to as echoes or ringing, has been described as a form of local, short term memory which may influence the ability of the auditory system to detect gaps in an acoustic stimulus such as speech...
July 2016: PLoS Computational Biology
https://www.readbyqxmd.com/read/27255816/large-cross-sectional-study-of-presbycusis-reveals-rapid-progressive-decline-in-auditory-temporal-acuity
#20
Erol J Ozmeral, Ann C Eddins, D Robert Frisina, David A Eddins
The auditory system relies on extraordinarily precise timing cues for the accurate perception of speech, music, and object identification. Epidemiological research has documented the age-related progressive decline in hearing sensitivity that is known to be a major health concern for the elderly. Although smaller investigations indicate that auditory temporal processing also declines with age, such measures have not been included in larger studies. Temporal gap detection thresholds (TGDTs; an index of auditory temporal resolution) measured in 1071 listeners (aged 18-98 years) were shown to decline at a minimum rate of 1...
July 2016: Neurobiology of Aging
keyword
keyword
59168
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"