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https://www.readbyqxmd.com/read/28936174/the-effect-of-velvet-antler-proteins-on-cardiac-microvascular-endothelial-cells-challenged-with-ischemia-hypoxia
#1
Xiang Xiao, Shuqiang Xu, Lin Li, Min Mao, Jinping Wang, Yanjun Li, Ziwei Wang, Fei Ye, Li Huang
Velvet antler (VA) is a precious traditional Chinese medicine that is capable of repeated regeneration. Based on the Chinese medicine theory of coordination the heart and kidneys, VA has been employed to treat heart diseases, including ischemic heart disease, heart failure, and arrhythmia. We examined the effects of VA proteins on primary cardiac microvascular endothelial cells (CMECs) that were subjected to ischemia-hypoxia (IH) to investigate their effects on and mechanism of action in the treatment of ischemic heart disease...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28916843/the-implicit-learning-of-metrical-and-non-metrical-rhythms-in-blind-and-sighted-adults
#2
Claudia Carrara-Augustenborg, Benjamin G Schultz
Forming temporal expectancies plays a crucial role in our survival as it allows us to identify the occurrence of temporal deviants that might signal potential dangers. The dynamic attending theory suggests that temporal expectancies are formed more readily for rhythms that imply a beat (i.e., metrical rhythms) compared to those that do not (i.e., nonmetrical rhythms). Moreover, metrical frameworks can be used to detect temporal deviants. Although several studies have demonstrated that congenital or early blindness correlates with modality-specific neural changes that reflect compensatory mechanisms, few have examined whether blind individuals show a learning advantage for auditory rhythms and whether learning can occur unintentionally and without awareness, that is, implicitly...
September 15, 2017: Psychological Research
https://www.readbyqxmd.com/read/28894164/investigating-the-relationship-between-cerebrospinal-fluid-and-magnetic-induction-phase-shift-in-rabbit-intracerebral-hematoma-expansion-monitoring-by-mri
#3
Mingsheng Chen, Qingguang Yan, Jian Sun, Gui Jin, Mingxin Qin
In a prior study of intracerebral hemorrhage monitoring using magnetic induction phase shift (MIPS), we found that MIPS signal changes occurred prior to those seen with intracranial pressure. However, the characteristic MIPS alert is not yet fully explained. Combining the brain physiology and MIPS theory, we propose that cerebrospinal fluid (CSF) may be the primary factor that leads to hematoma expansion being alerted by MIPS earlier than with intracranial pressure monitoring. This paper investigates the relationship between CSF and MIPS in monitoring of rabbit intracerebral hemorrhage models, which is based on the MIPS measurements data, the quantified data on CSF from medical images and the amount of injected blood in the rabbit intracerebral hemorrhage model...
September 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28888731/mechanism-for-detecting-napl-using-electrical-resistivity-imaging
#4
Todd Halihan, Valina Sefa, Tom Sale, Mark Lyverse
The detection of non-aqueous phase liquid (NAPL) related impacts in freshwater environments by electrical resistivity imaging (ERI) has been clearly demonstrated in field conditions, but the mechanism generating the resistive signature is poorly understood. An electrical barrier mechanism which allows for detecting NAPLs with ERI is tested by developing a theoretical basis for the mechanism, testing the mechanism in a two-dimensional sand tank with ERI, and performing forward modeling of the laboratory experiment...
August 19, 2017: Journal of Contaminant Hydrology
https://www.readbyqxmd.com/read/28887176/ecoacoustic-codes-and-ecological-complexity
#5
Almo Farina
Multi-layer communication and sensing network assures the exchange of relevant information between animals and their umwelten, imparting complexity to the ecological systems. Individual soniferous species, the acoustic community, and soundscape are the three main operational levels that comprise this multi-layer network. Acoustic adaptation and acoustic niche are two more important mechanisms that regulate the acoustic performances at the first level while the acoustic community model explains the complexity of the interspecific acoustic network at the second level...
September 5, 2017: Bio Systems
https://www.readbyqxmd.com/read/28886805/using-raman-spectroscopy-to-detect-and-diagnose-skin-cancer-in%C3%A2-vivo
#6
REVIEW
Jianhua Zhao, Haishan Zeng, Sunil Kalia, Harvey Lui
Raman spectroscopy provides a noninvasive bedside tool that captures unique optical signals via molecular vibrations in tissue samples. Raman theory was discovered at the beginning of the twentieth century, but it was not until the past few decades that it has been used to differentiate skin neoplasms. We provide a brief description of Raman spectroscopy for in vivo skin cancer diagnosis, including the physical principles underlying Raman spectroscopy, its advantages, typical spectra of skin pathologies, and its clinical application for aiding skin cancer diagnosis...
October 2017: Dermatologic Clinics
https://www.readbyqxmd.com/read/28886481/identifying-sleep-spindles-with-multichannel-eeg-and-classification-optimization
#7
Ning Mei, Michael D Grossberg, Kenneth Ng, Karen T Navarro, Timothy M Ellmore
Researchers classify critical neural events during sleep called spindles that are related to memory consolidation using the method of scalp electroencephalography (EEG). Manual classification is time consuming and is susceptible to low inter-rater agreement. This could be improved using an automated approach. This study presents an optimized filter based and thresholding (FBT) model to set up a baseline for comparison to evaluate machine learning models using naïve features, such as raw signals, peak frequency, and dominant power...
September 1, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28885165/synchronization-control-for-a-class-of-discrete-time-dynamical-networks-with-packet-dropouts-a-coding-decoding-based-approach
#8
Licheng Wang, Zidong Wang, Qing-Long Han, Guoliang Wei
The synchronization control problem is investigated for a class of discrete-time dynamical networks with packet dropouts via a coding-decoding-based approach. The data is transmitted through digital communication channels and only the sequence of finite coded signals is sent to the controller. A series of mutually independent Bernoulli distributed random variables is utilized to model the packet dropout phenomenon occurring in the transmissions of coded signals. The purpose of the addressed synchronization control problem is to design a suitable coding-decoding procedure for each node, based on which an efficient decoder-based control protocol is developed to guarantee that the closed-loop network achieves the desired synchronization performance...
September 6, 2017: IEEE Transactions on Cybernetics
https://www.readbyqxmd.com/read/28883069/probing-the-frontiers-of-particle-physics-with-tabletop-scale-experiments
#9
REVIEW
David DeMille, John M Doyle, Alexander O Sushkov
The field of particle physics is in a peculiar state. The standard model of particle theory successfully describes every fundamental particle and force observed in laboratories, yet fails to explain properties of the universe such as the existence of dark matter, the amount of dark energy, and the preponderance of matter over antimatter. Huge experiments, of increasing scale and cost, continue to search for new particles and forces that might explain these phenomena. However, these frontiers also are explored in certain smaller, laboratory-scale "tabletop" experiments...
September 8, 2017: Science
https://www.readbyqxmd.com/read/28868785/incomplete-initial-nutation-diffusion-imaging-an-ultrafast-single-scan-approach-for-diffusion-mapping
#10
Andrada Ianuş, Noam Shemesh
PURPOSE: Diffusion MRI is confounded by the need to acquire at least two images separated by a repetition time, thereby thwarting the detection of rapid dynamic microstructural changes. The issue is exacerbated when diffusivity variations are accompanied by rapid changes in T2 . The purpose of the present study is to accelerate diffusion MRI acquisitions such that both reference and diffusion-weighted images necessary for quantitative diffusivity mapping are acquired in a single-shot experiment...
September 3, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28866594/wavelet-based-visual-analysis-of-dynamic-networks
#11
Alcebiades Dal Col, Paola Valdivia, Fabiano Petronetto, Fabio Dias, Claudio T Silva, L Gustavo Nonato
Dynamic networks naturally appear in a multitude of applications from different fields. Analyzing and exploring dynamic networks in order to understand and detect patterns and phenomena is challenging, fostering the development of new methodologies, particularly in the field of visual analytics. In this work, we propose a novel visual analytics methodology for dynamic networks, which relies on the spectral graph wavelet theory. We enable the automatic analysis of a signal defined on the nodes of the network, making viable the robust detection of network properties...
August 29, 2017: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/28863485/detecting-dynamical-changes-in-time-series-by-using-the-jensen-shannon-divergence
#12
D M Mateos, L E Riveaud, P W Lamberti
Most of the time series in nature are a mixture of signals with deterministic and random dynamics. Thus the distinction between these two characteristics becomes important. Distinguishing between chaotic and aleatory signals is difficult because they have a common wide band power spectrum, a delta like autocorrelation function, and share other features as well. In general, signals are presented as continuous records and require to be discretized for being analyzed. In this work, we introduce different schemes for discretizing and for detecting dynamical changes in time series...
August 2017: Chaos
https://www.readbyqxmd.com/read/28855037/-mechanism-of-chlorogenic-acid-in-apoptotic-regulation-through-notch1-%C3%A2-pathway-in-non-small-cell-lung-carcinoma-in-animal-level
#13
Wei Li, Xu Liu, Guoqian Zhang, Linlin Zhang
BACKGROUND: It has been proven that chlorogenic acids can produce anticancer effects by regulating cell cycle, inducing apoptosis, inhibiting cell growth, Notch signaling pathways are closely related to many human tumors. The aim of this study is to study the mechanism of chlorogenic acid on apoptosis of non-small lung cancer through Notch1 pathway in animal level, and hope to provide theory basis on clinical treatment and research aimed at targeting Notch1 signaling in non-small cell carcinoma (NSCLC)...
August 20, 2017: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
https://www.readbyqxmd.com/read/28837964/global-processing-of-random-phase-radial-frequency-patterns-but-not-modulated-lines
#14
Robert J Green, J Edwin Dickinson, David R Badcock
Previously, researchers have used circular contours with sinusoidal deformations of the radius (radial frequency [RF] patterns) to investigate the underlying processing involved in simple shape perception. On finding that the rapid improvement in sensitivity to deformation as more cycles of modulation were added was greater than expected from probability summation across sets of local independent detectors, they concluded that global integration of contour information was occurring. More recently, this conclusion has been questioned by researchers using a method of calculating probability summation derived from signal detection theory (Baldwin, Schmidtmann, Kingdom, & Hess, 2016)...
August 1, 2017: Journal of Vision
https://www.readbyqxmd.com/read/28817986/formation-of-artifactual-dmpo-oh-spin-adduct-in-acid-solutions-containing-nitrite-ions
#15
Tetsuya Takayanagi, Hirokazu Kimiya, Tatsushi Ohyama
We investigated aqueous solutions containing nitrite ions and DMPO (5,5-dimethyl-1-pyrroline-N-oxide) by electron spin resonance (ESR) in the pH range from 1 to 6. A DMPO-OH signal was observed below pH 3.0 in the presence of nitrite ions, whereas in the absence of nitrite ion, an extremely weak signal was observed below pH 1.5. Addition of methanol, a hydroxyl radical scavenger, to this system did not lead to the appearance of a detectable DMPO-CH2OH signal. The possibility of this DMPO-OH signal being due to a genuine spin trapping process with hydroxyl radical was, therefore, ruled out...
September 5, 2017: Free Radical Research
https://www.readbyqxmd.com/read/28817080/feasibility-study-of-an-optical-caustic-plasmonic-light-scattering-sensor-for-human-serum-anti-dengue-protein-e-antibody-detection
#16
Antonio A García, Lina S Franco, Miguel A Pirez-Gomez, José L Pech-Pacheco, Jorge F Mendez-Galvan, Carlos Machain-Williams, Lourdes Talavera-Aguilar, José H Espinosa-Carrillo, Miriam M Duarte-Villaseñor, Christian Be-Ortiz, Luz E Espinosa-de Los Monteros, Ariel Castillo-Pacheco, Julian E Garcina-Rejon
Antibody detection and accurate diagnosis of tropical diseases is essential to help prevent the spread of disease. However, most detection methods lack cost-effectiveness and field portability, which are essential features for achieving diagnosis in a timely manner. To address this, 3D-printed oblate spheroid sample chambers were fabricated to measure green light scattering of gold nanoparticles using an optical caustic focus to detect antibodies. Scattering signals of 20-200 nm gold nanoparticles using a green laser were compared to green light emitting diode (LED) light source signals and to Mie theory...
August 17, 2017: Diagnostics
https://www.readbyqxmd.com/read/28815431/central-peripheral-differences-in-audiovisual-and-visuotactile-event-perception
#17
Yi-Chuan Chen, Daphne Maurer, Terri L Lewis, Charles Spence, David I Shore
We examined audiovisual and visuotactile integration in the central and peripheral visual field using visual fission and fusion illusions induced by sounds or taps. The fission illusion occurs when a single flash is perceived as two flashes if paired with two beeps or taps; the fusion illusion, by contrast, occurs when two flashes are perceived as a single flash if the flashes are paired with a single beep or tap. Beeps and taps induced similar patterns of illusions: the fission illusion was larger in the periphery than in the center, whereas the fusion illusion was larger in the center than in the periphery...
August 16, 2017: Attention, Perception & Psychophysics
https://www.readbyqxmd.com/read/28807647/endogenous-visuospatial-attention-increases-visual-awareness-independent-of-visual-discrimination-sensitivity
#18
Marine Vernet, Shruti Japee, Savannah Lokey, Sara Ahmed, Valentinos Zachariou, Leslie G Ungerleider
Visuospatial attention often improves task performance by increasing signal gain at attended locations and decreasing noise at unattended locations. Attention is also believed to be the mechanism that allows information to enter awareness. In this experiment, we assessed whether orienting endogenous visuospatial attention with cues differentially affects visual discrimination sensitivity (an objective task performance) and visual awareness (the subjective feeling of perceiving) during the same discrimination task...
August 11, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28806928/colour-polymorphic-lures-exploit-innate-preferences-for-spectral-versus-luminance-cues-in-dipteran-prey
#19
Thomas E White, Darrell J Kemp
BACKGROUND: Theory predicts that colour polymorphism may be favored by variation in the visual context under which signals are perceived. The context encompasses all environmental determinants of light availability and propagation, but also the dynamics of perception in receivers. Color vision involves the neural separation of information into spectral versus luminance channels, which often differentially guide specific tasks. Here we explicitly tested whether this discrete perceptual basis contributes to the maintenance of polymorphism in a prey-luring system...
August 14, 2017: BMC Evolutionary Biology
https://www.readbyqxmd.com/read/28806670/transmission-surface-plasmon-resonance-techniques-and-their-potential-biosensor-applications
#20
REVIEW
Chutiparn Lertvachirapaiboon, Akira Baba, Sanong Ekgasit, Kazunari Shinbo, Keizo Kato, Futao Kaneko
Transmission surface plasmon resonance (TSPR) is an unusual extraordinary optical transmission that is more transparent at certain wavelengths than expected by classical theory. The three main plasmonic structures that providing this phenomenon are nanohole arrays, diffraction gratings, and nanoslit arrays. This extraordinary optical transmission phenomenon is produced as a result of surface plasmon excitations. The shifting in TSPR responses upon changing of dielectric environment at the surface of a metallic film was observed...
August 1, 2017: Biosensors & Bioelectronics
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