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Preterm rupture of membranes

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https://www.readbyqxmd.com/read/28535541/contribution-of-amniotic-fluid-along-gestation-to-the-prediction-of-perinatal-mortality-in-women-with-early-preterm-premature-rupture-of-membranes
#1
Teresa Cobo, Jordina Munrós, José Ríos, Janisse Ferreri, Federico Migliorelli, Núria Baños, Eduard Gratacós, Montse Palacio
INTRODUCTION: To evaluate the largest vertical pocket (LVP) of amniotic fluid as a time-dependent factor to predict perinatal mortality in women with early preterm premature rupture of membranes (EPPROM). MATERIAL AND METHODS: Observational cohort study of singleton pregnancies with EPPROM <24 weeks. Termination of pregnancy (TOP) was considered if the LVP was <2 cm at 7 days. The maternal and neonatal characteristics of ongoing pregnancies were recorded. Prediction of perinatal mortality was estimated based on the influence of the LVP as a time-dependent factor after adjustment for maternal age, prior invasive procedure, and gestational age at EPPROM...
May 24, 2017: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/28526452/gestational-age-at-initiation-of-17-alpha-hydroxyprogesterone-caproate-and-recurrent-preterm-birth
#2
Angela Ning, Catherine J Vladutiu, Sarah K Dotters-Katz, William H Goodnight, Tracy A Manuck
BACKGROUND: Preterm birth (PTB) is the leading cause of neonatal morbidity and mortality in non-anomalous neonates in the US. Women with a previous early spontaneous PTB are at highest risk for recurrence. Weekly intramuscular 17-alpha hydroxyprogesterone caproate (17-OHPC) reduces the risk of recurrent prematurity. Though current guidelines recommend 17-OHPC initiation between 16-20 weeks', in clinical practice, 17-OHPC is started across a spectrum of gestational ages. OBJECTIVE: To examine the relationship between the gestational age at 17-OHPC initiation and recurrent PTB among women a prior spontaneous PTB 16-28 weeks' gestation...
May 16, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28508414/cervical-cerclage-placed-before-14%C3%A2-weeks-gestation-in-women-with-one-previous-midtrimester-loss-a-population-based-cohort-study
#3
Margaret E Harpham, Charles S Algert, Christine L Roberts, Jane B Ford, Antonia W Shand
BACKGROUND: Cervical cerclage is used in an attempt to reduce recurrence risk of preterm birth, but evidence for use is limited. AIMS: To compare pregnancy outcomes among women with a single previous midtrimester delivery when managed with or without a cervical cerclage. MATERIALS AND METHODS: Population-based cohort study of all women in New South Wales, Australia with a singleton pregnancy ending in birth/miscarriage ≥14 and <28 weeks, between 2003 and 2011...
May 16, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/28502201/prediction-of-chorioamnionitis-in-cases-of-intraamniotic-infection-by-ureaplasma-urealyticum-in-women-with-very-preterm-premature-rupture-of-membranes-or-preterm-labour
#4
Rocio Revello, María José Alcaide, Daniel Abehsera, María Martin-Camean, Mafalda Sousa E Faro Gomes, Bárbara Alonso-Luque, Jose L Bartha
OBJECTIVES: First, to determinate the frequency of chorioamnionitis and funisitis in cases of intramniotic detection of Ureaplasma urealyticum. And second, to assess the predictive capability of some biological markers in the amniotic fluid of these women to predict histological inflammation. SUBJECTS AND METHODS: We prospectively studied 20 cases of women with premature rupture of membranes or preterm labour (PROM) or preterm labour and intraamniotic detection of Ureaplasma urealyticum...
May 14, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28497897/expression-profile-of-heat-shock-proteins-in-placental-tissues-of-patients-with-preterm-prelabor-rupture-of-membranes-and-spontaneous-preterm-labor-with-intact-membranes
#5
Lenka Dvorakova, Katarina Ivankova, Ladislav Krofta, Ilona Hromadnikova
PROBLEM: Investigating the stress response in the central cotyledon zone of placental tissue in pregnancies with PPROM, PTB, and at term in labor. METHOD OF STUDY: Gene expression of Hsp27, Hsp60, Hsp70, Hsp90, and HspBP1 was compared between these particular groups. Correlation between variables including Hsp gene expression in placental tissue and the gestational age at delivery, WBC count at admission, and serum levels of CRP at admission in patients with PPROM and PTB was determined...
May 12, 2017: American Journal of Reproductive Immunology: AJRI
https://www.readbyqxmd.com/read/28488223/ultrasonic-identification-of-pump-twin-by-dual-gate-doppler-in-a-monochorionic-triamniotic-triplet-twin-reversed-arterial-perfusion-sequence-before-preventative-radiofrequency-ablation-a-case-report
#6
Yuichiro Takahashi, Shigenori Iwagaki, Rika Chiaki, Kazuhiko Asai, Masako Matsui, Ichiro Kawabata
We performed a dual-gate Doppler examination for a twin reversed arterial perfusion (TRAP) sequence in a monochorionic-triamniotic triplet pregnancy at 16 weeks of gestation and were able to identify the pump twin by arterial pulse rate synchronicity. We performed radiofrequency ablation to coagulate blood flow in the acardius at 16 weeks of gestation without any postoperative complication. At 29 weeks of gestation, we performed a cesarean section due to preterm rupture of the membranes and the patient delivered 1167/1237-g female neonates and a macerated acardius...
May 9, 2017: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/28486367/intra-amniotic-dye-alternatives-for-the-diagnosis-of-preterm-prelabor-rupture-of-membranes
#7
Kayla E Ireland, Emma I Rodriguez, Ometeotl M Acosta, Patrick S Ramsey
Intra-amniotic dye instillation is a useful tool for evaluation of equivocal cases of preterm prelabor rupture of membranes and for genetic amniocentesis in multifetal gestation. Indigo carmine, the most used and studied dye, is no longer available. We sought to provide a resource of potential dyes for clinical use that summarizes dosing along with maternal, fetal, and neonatal outcomes. We reviewed the literature evaluating the use of alternative agents. Sodium fluorescein has proven clinical usefulness but has side effects when used intravenously...
June 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28483819/short-term-and-long-term-outcomes-of-preterm-neonates-with-acute-severe-pulmonary-hypertension-following-rescue-treatment-with-inhaled-nitric-oxide
#8
Michelle Baczynski, Shannon Ginty, Dany E Weisz, Patrick J McNamara, Edmond Kelly, Prakeshkumar Shah, Amish Jain
OBJECTIVE: To describe short-term and long-term outcomes of preterm neonates with severe acute pulmonary hypertension (aPHT) in relation to response to rescue inhaled nitric oxide (iNO) therapy. DESIGN: Retrospective cohort studyover a 6 year period. SETTING: Tertiary neonatal intensive care unit. PATIENTS: 89 neonates <35 weeks gestational age (GA) who received rescue iNO for aPHT, including 62 treated at ≤3 days of age (early aPHT)...
May 8, 2017: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/28482725/umbilical-cord-blood-and-maternal-visfatin-pbef-nampt-concentrations-in-preterm-birth-with-and-without-preterm-premature-rupture-of-membranes
#9
Tereza Pavlová, Filip Zlámal, Zbyněk Šplíchal, Josef Tomandl, Zuzana Hodická, Pavel Ventruba, Julie Bienertová-Vašků
OBJECTIVES: The aim of the study is to investigate differences in visfatin concentrations between mothers with term and preterm birth (PTB) and between mothers who delivered within 7 days and after more than 7 days following admission for PTB/preterm premature rupture of membranes (PPROM). METHODS: Maternal peripheral blood and cord blood was collected from 56 mothers with PTB (31 with PPROM) and 71 mothers with term delivery (3 with PPROM). RESULTS: Maternal visfatin concentration was significantly higher for given gestational age in PTBs compared to term deliveries (p = 0...
May 9, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28481445/optimising-fertility-outcomes-for-women-with-early-stage-cervical-cancer-when-less-is-more
#10
Efterpi Tingi, Emma J Crosbie, Gemma Owens
Radical hysterectomy and pelvic lymphadenectomy is standard management for early-stage cervical cancer. Radical trachelectomy achieves equivalent oncological outcomes to hysterectomy thus providing an alternative for women who wish to preserve their fertility (Xu et al. Acta Obstet Gynecol Scand 2011; 90: 1200-09). Trachelectomy offers the potential for pregnancy but poor obstetric sequelae, including second trimester miscarriage, preterm premature rupture of membranes (PPROM) and preterm delivery are common, likely due to reduced mechanical support from a shortened cervix and ascending infection...
May 8, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28476444/early-and-late-preterm-premature-rupture-of-membranes
#11
EDITORIAL
Kuan-Chin Wang, Wen-Ling Lee, Peng-Hui Wang
No abstract text is available yet for this article.
May 2, 2017: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/28475395/patient-and-prescriber-factors-and-the-prolongation-of-antibiotics-after-birth-in-infants-less-than-29-weeks
#12
M R Al Turk, R J Baier
OBJECTIVE: To delineate whether patient related or prescriber related factors account for the prolongation of antibiotic therapy beyond 48 hours in premature infants whose initial blood cultures are negative. METHODS: Retrospective review of infants born <29 weeks born between January 2011 and December 2012. Infants who had positive blood cultures or who died in the first 48 hours were excluded from analysis. Antibiotic courses were categorized as prolonged if antibiotics were continued for greater than 48 hours and not prolonged if antibiotics were stopped by 48 hours...
May 5, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28454700/what-is-the-impact-of-placental-tissue-damage-after-laser-surgery-for-twin-twin-transfusion-syndrome-a-secondary-analysis-of-the-solomon-trial
#13
Joost Akkermans, Saskia M de Vries, Depeng Zhao, Suzanne H P Peeters, Frans J Klumper, Johanna M Middeldorp, Dick Oepkes, Femke Slaghekke, Enrico Lopriore
BACKGROUND: The introduction of the Solomon technique for the treatment of twin-twin transfusion syndrome (TTTS) increased placental exposure to laser energy. This study aims to identify the impact of power and energy used in laser treatment on placental tissue and pregnancy outcome. METHODS: Pictures of all dye-injected placentas since the start of the Solomon trial were analyzed. Placental damage was scored using a grading system including visual scar depth and affected proportion of the vascular equator...
April 2017: Placenta
https://www.readbyqxmd.com/read/28446135/comparison-of-rapid-immunoassays-for-rupture-of-fetal-membranes
#14
Irogue Igbinosa, Ferney A Moore, Cheri Johnson, Jon E Block
BACKGROUND: Rupture of membranes (ROM) before the onset of uterine contractions, particularly in pregnancies less than 37 weeks gestational age, is a common diagnostic problem in obstetrical practice. Timely detection of ROM is vital to support gestational age-specific interventions to optimize perinatal outcomes and minimize the risk of serious complications such as preterm delivery, fetal distress and maternal/fetal infections. Rapid bedside immunoassay tests designed to detect amniotic fluid proteins in cervicovaginal fluids have emerged as valuable clinical tools to provide timely ROM diagnosis...
April 26, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28440092/comparison-of-maternal-omentin-1-levels-and-genetic-variability-between-spontaneous-term-and-preterm-births
#15
Zbyněk Šplíchal, Filip Zlámal, Jan Máchal, Jolana Lipková, Tereza Pavlová, Zuzana Hodická, Pavel Ventruba, Anna Vašků, Julie Bienertová-Vašků
OBJECTIVE: To determine maternal omentin-1 levels and genetic variability in the omentin-1 gene in women with spontaneous term and preterm births. MATERIAL AND METHODS: Maternal serum omentin-1 levels and the role of the omentin-1 Val109Asp (rs2274907) polymorphism were evaluated in 32 women with spontaneous term birth (sTB) and 30 women with spontaneous preterm birth (sPTB) including women with (n = 16) and without (n = 14) preterm premature rupture of membranes (PPROM)...
April 25, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28434005/chorioamniotic-membrane-separation-after-fetoscopic-laser-photocoagulation
#16
Mayumi Takano, Masahiko Nakata, Susumu Murata, Masahiro Sumie, Mineto Morita
INTRODUCTION: This study aimed to investigate the risk factors, incidence, and influence on the perinatal outcome of chorioamniotic membrane separation (CMS) after fetoscopic laser photocoagulation (FLP). MATERIAL AND METHODS: This retrospective study included 312 women who underwent FLP for twin-to-twin transfusion syndrome (TTTS). Clinical records were used to review obstetrical examinations, complications, operative data, ultrasonographic findings, and perinatal and neonatal follow-up data in all patients...
April 22, 2017: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/28431858/third-trimester-preterm-and-term-premature-rupture-of-membranes-is-there-any-difference-in-maternal-characteristics-and-pregnancy-outcomes
#17
Ivana Chandra, Lizhou Sun
BACKGROUND: The clinical significance and management of preterm premature rupture of membranes (PPROM) remains a topic of a controversy. Although PROM is associated with a low rate of complications, PPROM may lead to significant neonatal and maternal morbidity. METHODS: We performed a retrospective study of 714 women who presented to Jiangsu Province Hospital with third trimester PPROM or PROM between January and December 2015. The data were analyzed by SPSS; the significance of maternal characteristics, and maternal and neonatal outcomes were tested using Student's t test and the χ(2) test...
April 18, 2017: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/28426651/association-of-candidate-gene-polymorphisms-with-clinical-subtypes-of-preterm-birth-in-a-latin-american-population
#18
Lucas G Gimenez, Allison M Momany, Fernando A Poletta, Hugo B Krupitzki, Juan A Gili, Tamara D Busch, Cesar Saleme, Viviana R Cosentino, Mariela S Pawluk, Hebe Campaña, Enrique C Gadow, Jeffrey C Murray, Jorge S Lopez-Camelo
BACKGROUND: Preterm birth (PTB) is the leading cause of neonatal mortality and morbidity. PTB is often classified according to clinical presentation: Idiopathic (PTB-I), preterm premature rupture of membranes (PTB-PPROM), and medically induced (PTB-M). The aim of this study was to evaluate the associations between specific candidate genes and clinical subtypes of PTB. METHODS: 24 SNPs were genotyped in 18 candidate genes in 709 infant triads. Of them, 243 were PTB-I, 256 PTB-PPROM, and 210 PTB-M...
April 20, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28423971/intrauterine-infection-immune-system-and-premature-birth
#19
Fernanda Rodrigues Helmo, Eduardo Arthur Rodovalho Alves, Renata Alves de Andrade Moreira, Viviane Oliveira Severino, Laura Penna Rocha, Maria Luíza Gonçalves Dos Reis Monteiro, Marlene Antônia Dos Reis, Renata Margarida Etchebehere, Juliana Reis Machado, Rosana Rosa Miranda Corrêa
Preterm birth accounts for nearly one million deaths among children under five years of age, and although its etiopathogenesis is not fully elucidated, ascending intrauterine infection and fetal inflammatory response seem to be the main triggers. The intense inflammatory response mediated by IL-1β, TNF-α, PAF, IFN-γ and IL-6, PGE2 and MMP-1 and MMP-9 causes fetal membrane damage and rupture, increased uterine contractions and biochemical and structural changes in the cervix. Furthermore, preterm neonates have deficient innate and adaptive immune responses characterized by reduced levels of IgG, opsonization and phagocytosis, as well as increased activation of Th1 cells in relation to Th2 cells...
April 20, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28420507/asymptomatic-pyuria-in-pregnant-women-during-the-first-trimester-is-associated-with-an-increased-risk-of-adverse-obstetrical-outcomes
#20
Yun-Ju Lai, Te-Yao Hsu, Kuo-Chung Lan, Hao Lin, Chia-Yu Ou, Hung-Chun Fu, Ching-Chang Tsai
OBJECTIVE: Urinalysis is included in the prenatal examination in the first trimester in Taiwan, in contrast to Western countries. We aimed to investigate whether asymptomatic pyuria as detected by urinalysis was associated with adverse perinatal outcomes. MATERIALS AND METHODS: A total of 1187 singleton pregnant women who received prenatal care at Kaohsiung Chang Gung Memorial Hospital between January 2012 and December 2013 were included for retrospective analysis...
April 2017: Taiwanese Journal of Obstetrics & Gynecology
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