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Iliofemoral DVT

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https://www.readbyqxmd.com/read/27914131/the-role-of-pharmacomechanical-endovascular-intervention-for-iliofemoral-vein-thrombosis-compared-to-conventional-anticoagulation-therapy
#1
In Sub Kim, Won Min Jo
Although anticoagulation therapy is the primary treatment for deep vein thrombosis (DVT), it has not been associated with the rapid recanalization of the venous occlusion. Moreover, it is associated with long-term disability due to post-thrombotic syndrome (PTS). In contrast, pharmacomechanical endovascular intervention (PMI) results in more rapid clinical improvement in DVT patients, but there are few reports on its long-term outcomes. This retrospective study evaluated the clinical effectiveness of PMI compared to conventional anticoagulation therapy (ACA) for acute and subacute iliofemoral DVT...
January 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/27903022/-recanalization-techniques-for-venous-outflow-obstruction
#2
Michael K W Lichtenberg, Houman Jalaie
Deep vein thrombosis (DVT) is associated with a high cost burden for health care systems because of secondary cost intensive complications like pulmonary embolism and especially the post thrombotic syndrome (PTS). The current standard therapy of anticoagulation for DVT therapy has not changed through the years leaving patients especially with iliofemoral vein thrombus on a high-risk situation for developing PTS. Current study situation for endovascular treatment of iliofemoral DVT treatment gives a rationale for active thrombus removal using catheter directed therapy (CDT) or pharmacomechanical thrombectomy (PMT) which improves valvular vein function and luminal patency reducing the potential complication of PTS...
November 2016: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/27830895/thrombolysis-for-acute-deep-vein-thrombosis
#3
REVIEW
Lorna Watson, Cathryn Broderick, Matthew P Armon
BACKGROUND: Standard treatment for deep vein thrombosis aims to reduce immediate complications. Use of thrombolysis or clot dissolving drugs could reduce the long-term complications of post-thrombotic syndrome (PTS) including pain, swelling, skin discolouration, or venous ulceration in the affected leg. This is the third update of a review first published in 2004. OBJECTIVES: To assess the effects of thrombolytic therapy and anticoagulation compared to anticoagulation alone for the management of people with acute deep vein thrombosis (DVT) of the lower limb as determined by the effects on pulmonary embolism, recurrent venous thromboembolism, major bleeding, post-thrombotic complications, venous patency and venous function...
November 10, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27814432/pharmacomechanical-thrombectomy-for-iliofemoral-deep-vein-thrombosis
#4
REVIEW
Lindsay Robertson, Olivia McBride, Anne Burdess
BACKGROUND: Deep venous thrombosis (DVT) occurs in approximately one in 1000 adults every year, and has an annual mortality of 14.6%. In particular, iliofemoral DVT can lead to recurrent thrombosis and post-thrombotic syndrome (PTS), a painful condition which can lead to chronic venous insufficiency, oedema, and ulceration. It causes significant disability, impaired quality of life, and economic burden. Early thrombus removal techniques have been advocated in patients with an iliofemoral DVT in order to improve vein patency, prevent valvular dysfunction, and reduce future complications, such as post-thrombotic syndrome and venous ulceration...
November 4, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27784386/-relationship-of-serum-d-dimer-fibrinogen-c-reactive-protein-and-interleukin-6-with-thrombus-dissolution-volume-in-acute-iliac-femoral-vein-thrombosis-model-rats
#5
Qi Wang, Si-Qiao Sun, Zhi-Hua Cheng, Zhong-Ying Wang, Chao Liu
OBJECTIVE: To explore the relationship among the serum D- two polymer, fibrinogen, C reactive protein and interleukin 6 and thrombus dissolution volume in acute iliac femoral venous thrombosis model rats. METHODS: A total of 60 rats were randomly divided into 3 groups: deep venous thrombosis group (DVT group), sham operation group and normal control group. In DVT group the single side of the iliofemoral vein incomplete with micro vessel was cliped under chloral hydrate anesthesia; in sham operation group the single side of the iliofemoral vein should be explored without using micro vessel clip under chloral hydrate anesthesia; the and normal control group only experienced chloral hydrate anesthesia...
October 2016: Zhongguo Shi Yan Xue Ye Xue za Zhi
https://www.readbyqxmd.com/read/27664152/endovascular-treatment-of-thrombosis-and-embolism
#6
Ahmet Yigit Goktay, Cagin Senturk
Deep venous thrombosis (DVT) is a common disorder with a significant mortality rate. Successful endovascular treatment of acute DVT is most likely to be achieved in patients with recently formed thrombus, (<10-14 days) with acute iliofemoral DVT. Endovascular treatment options include: Catheter-directed thrombolysis (CDT), pharmacomechanical catheter-directed thrombolysis (PCDT), percutaneous aspiration thrombectomy (PAT), vena cava filter protection, venous balloon dilatation and venous stent implantation...
September 24, 2016: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/27638999/time-taken-to-the-maximum-increase-in-the-oxygenated-hemoglobin-level-in-calf-muscle-as-a-predictor-of-mild-and-moderate-post-thrombotic-syndrome
#7
Takashi Yamaki, Yuki Hasegawa, Atsuyoshi Osada, Hisato Konoeda, Atsumori Hamahata, Masakazu Ochi, Motohiro Nozaki, Hiroyuki Sakurai
BACKGROUND: Near-infrared spectroscopy (NIRS) allows continuous noninvasive monitoring of changes in the tissue levels of oxygenated hemoglobin (O2Hb) and deoxygenated hemoglobin (HHb) and can identify the severity of chronic venous diseases. Here we investigated the predictors of post-thrombotic syndrome (PTS) using NIRS in patients with a first episode of deep venous thrombosis (DVT). METHODS: The study enrolled 129 patients with DVT. Risk factors in each patient were assessed at presentation...
October 2016: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/27638990/impact-of-inferior-vena-cava-thrombus-extension-on-thrombolysis-for-acute-iliofemoral-thrombosis
#8
Efthymios D Avgerinos, Omar El-Shazly, Geetha Jeyabalan, George Al-Khoury, Eric Hager, Michael J Singh, Michel S Makaroun, Rabih A Chaer
BACKGROUND: Inferior vena cava (IVC) thrombosis may occur in patients with iliofemoral deep venous thrombosis (DVT), and its impact on thrombolysis outcomes is poorly defined. This study compared outcomes of patients undergoing thrombolysis for acute iliofemoral DVT with and without IVC involvement. METHODS: Patients who underwent thrombolysis for iliofemoral DVT between May 2007 and March 2014 were identified from a prospectively maintained database and divided into two groups: those with IVC involvement and those without...
October 2016: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/27625083/incidence-and-risk-factors-of-deep-venous-thrombosis-in-asymptomatic-iliac-vein-compression-a-prospective-cohort-study
#9
Min-Kai Wu, Xiao-Yun Luo, Fu-Xian Zhang
BACKGROUND: Deep vein thrombosis (DVT) may be associated with iliac vein compression. Up to now, the majority of data has come from a retrospective study about the correlation between DVT and iliac vein compression. This prospective study was to determine the incidence of DVT in individuals with iliac vein compression and identify risk factors predictive of DVT. METHODS: A total of 500 volunteers without symptoms of venous diseases of lower extremities and overt risk factors of deep venous thrombosis between October 2011 and September 2012 in Shijitan Hospital were enrolled in this cohort study...
2016: Chinese Medical Journal
https://www.readbyqxmd.com/read/27618329/role-of-catheter-directed-thrombolysis-in-management-of-iliofemoral-deep-venous-thrombosis
#10
James X Chen, Deepak Sudheendra, S William Stavropoulos, Gregory J Nadolski
The treatment for iliofemoral deep venous thrombosis (DVT) is challenging, as the use of anticoagulation alone can be insufficient for restoring venous patency and thus lead to prolongation of acute symptoms and an increased risk of chronic complications, including venous insufficiency and postthrombotic syndrome (PTS). In these cases, earlier and more complete thrombus removal can ameliorate acute symptoms and reduce long-term sequelae. Endovascular therapies involving the use of pharmacologic, mechanical, and combined pharmacomechanical modalities have been developed to achieve these goals...
September 2016: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/27531087/incidence-and-outcomes-of-inferior-vena-cava-filter-thrombus-during-catheter-directed-thrombolysis-for-proximal-deep-venous-thrombosis
#11
Jianguang Jiang, Jianfei Tu, Zhongzhi Jia, Jiezhong Chen, Haitao Cao, Qingli Meng, Tyler A Fuller, Feng Tian
OBJECTIVE: To retrospectively evaluate the incidence and outcomes of inferior vena cava (IVC) filter thrombus during catheter-directed thrombolysis (CDT) for acute proximal deep venous thrombosis (DVT). METHODS: From October 2006 to June 2015, patients diagnosed with acute proximal DVT and received CDT after a retrievable IVC filter was placed were included. The incidence, treatment and outcomes of IVC filter thrombus during CDT were recorded and analyzed. RESULTS: A total of 189 patients (91 women, 98 men, mean age, 57...
August 12, 2016: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/27489392/a-case-of-may-thurner-syndrome
#12
Emilia Calvaresi, Mahesh Swaminathan, Janet Jokela
May-Thurner syndrome is the condition of the left common iliac vein being compressed between the right common iliac artery and the associated vertebral body. This condition has been linked to spontaneous episodes of deep vein thrombosis (DVT), especially in women aged 20-50, and it may contribute to the slightly higher tendency to develop left-sided (~56%) versus right-sided DVTs. A 50-year-old morbidly obese (BMI 42.7 kg/m(2)) female presented to the emergency room with acute left leg pain. Past medical history included asthma...
2016: Carle Selected Papers
https://www.readbyqxmd.com/read/27385298/right-sided-cockett-s-syndrome
#13
Bert Du Pont, Jurgen Verbist, Wouter Van den Eynde, Patrick Peeters
Background Cockett and Thomas described and named Cockett's syndrome in 1965, commonly referred to as iliac vein compression syndrome (IVCS). It is often found as underlying cause in iliofemoral deep venous thrombosis (DVT). They described the syndrome mostly seen on the left side and predominantly in women during the second to the fourth decade of life. In this article, we present a patient with a Cockett's syndrome on the right side. Case presentation Our patient is a 52-year old female with edema of the right leg since 4 months...
April 2016: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/27318046/the-next-frontier-of-office-based-inferior-vena-cava-filter-placement
#14
Ahmad Alsheekh, Anil Hingorani, Natalie Marks, Enrico Ascher
OBJECTIVE: There is an increasing number of procedures that traditionally were performed in the inpatient setting that are now becoming office-based procedures. These include peripheral endovascular procedures such as angiograms, angioplasties, dialysis access interventions, and treatment for venous insufficiency. We chose to evaluate the feasibility, safety of inferior vena cava (IVC) filter placement in the office-based setting. METHODS: All procedures were performed using local anesthesia, and ultrasound guidance for puncture...
July 2016: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/27250354/a-retrospective-comparison-of-ultrasound-assisted-catheter-directed-thrombolysis-and-catheter-directed-thrombolysis-alone-for-treatment-of-proximal-deep-vein-thrombosis
#15
Vladimir Y I G Tichelaar, Ellen E Brodin, Anders Vik, Trond Isaksen, Finn Egil Skjeldestad, Satish Kumar, Nora C Trasti, Kulbir Singh, John-Bjarne Hansen
BACKGROUND: Recent studies have suggested that catheter-directed thrombolysis (CDT) reduces development of post-thrombotic syndrome (PTS). Ultrasound-assisted CDT (USCDT) might enhance the efficiency of thrombolysis. We aimed to compare USCDT with CDT on efficacy, safety, development of PTS, and quality of life after long-term follow-up. METHODS: We describe a retrospective case series of 94 consecutive patients admitted with iliofemoral or more proximal deep vein thrombosis (DVT) to the University Hospital from 2002 to 2011, treated either with CDT or USCDT...
August 2016: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/27113791/lower-extremity-compartment-syndrome-in-the-setting-of-iliofemoral-deep-vein-thrombosis-phlegmasia-cerulea-dolens-and-factor-vii-deficiency
#16
Wahid Abdul, Ben Hickey, Chris Wilson
Acute compartment syndrome requires urgent fasciotomies to prevent irreversible muscle damage. We present a case of massive iliofemoral deep vein thrombosis (DVT) presenting as acute compartment syndrome. A healthy 21-year-old man presented with a 2-day history of worsening left leg pain with swelling and bluish discolouration. Clinical diagnosis of compartment syndrome secondary to phlegmasia cerulea dolens (PCD) was made and he underwent emergency fasciotomies. Postoperative venous duplex confirmed a massive iliofemoral DVT and intravenous heparin was started...
2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27087868/clinical-significance-of-the-soleal-vein-and-related-drainage-veins-in-calf-vein-thrombosis-in-autopsy-cases-with-massive-pulmonary-thromboembolism
#17
Ayako Ro, Norimasa Kageyama
OBJECTIVE: To clarify the histopathological characteristics of deep vein thrombosis (DVT) resulting in lethal pulmonary thromboembolism (PE). SUBJECTS AND METHODS: We investigated 100 autopsy cases of PE from limb DVT. The distribution and chronology of DVT in each deep venous segment were examined. Venous segments were classified into three groups: iliofemoral vein, popliteal vein and calf vein (CV). The CV was subdivided into two subgroups, drainage veins of the soleal vein (SV) and non drainage veins of SV...
2016: Annals of Vascular Diseases
https://www.readbyqxmd.com/read/26995437/catheter-directed-thrombolysis-in-management-of-postpartum-lower-limb-deep-venous-thrombosis-a-case-series
#18
B C Srinivas, Soumya Patra, C M Nagesh, Babu Reddy, C N Manjunath
Deep vein thrombosis (DVT) is a major health problem in pregnancy and postpartum period. Catheter-directed thrombolysis (CDT) is safe and effective in the management of symptomatic DVT. Value of CDT in postpartum DVT is not fully evaluated. We describe five patients presenting with acute iliofemoral DVT in their early postpartum period who were treated with mechanical thromboaspiration and CDT. The CDT was done using streptokinase infusion and unfractionated heparin. Percutaneous angioplasty was done in patients with symptomatic residual lesion following thrombolysis...
December 2015: Indian Heart Journal
https://www.readbyqxmd.com/read/26993862/aspiration-thrombectomy-using-a-large-size-catheter-for-acute-lower-extremity-deep-vein-thrombosis
#19
Zhongzhi Jia, Jianfei Tu, Jinwei Zhao, Baosheng Ren, Feng Tian, Kai Wang, Shaoqin Li, Guomin Jiang
OBJECTIVE: This study retrospectively evaluated the safety and efficacy of aspiration thrombectomy using a large-size catheter for acute lower extremity deep vein thrombosis (DVT). METHODS: All patients who underwent aspiration thrombectomy using 9F or 10F catheters for acute lower extremity DVT were included and analyzed. Aspiration thrombectomy was performed in all patients. Additional intravenous thrombolysis was performed in patients with residual thrombus, and stent placement was performed in patients with iliac vein compression syndrome...
April 2016: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/26992613/intrapartum-temporary-inferior-vena-cava-filters-are-rarely-indicated-in-pregnant-women-with-deep-venous-thromboses
#20
Hiromi Konishi, Takekazu Miyoshi, Reiko Neki, Tetsuya Fukuda, Hatsue Ishibashi-Ueda, Takeshi Ogo, Norifumi Nakanishi, Jun Yoshimatsu
OBJECTIVE: We previously demonstrated the usefulness of temporary inferior vena cava filters (t-IVCFs) to prevent pulmonary thromboembolism in pregnant women with deep venous thrombosis (DVT). However, there is currently no consensus on the indications for intrapartum t-IVCF in pregnant women with DVT. In this study, we re-evaluated the safety and usefulness of t-IVCF inserted in this condition. METHODS: A retrospective evaluation in a single center was performed of 45 Japanese patients (54 pregnancies) with DVT between 1989 and 2014...
October 2015: Journal of Vascular Surgery. Venous and Lymphatic Disorders
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