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https://www.readbyqxmd.com/read/29775039/update-on-neonatal-cardiopulmonary-resuscitation
#1
(no author information available yet)
An update of the national recommendations on neonatal resuscitation elaborated by the Neonatal Resuscitation Work Area of the Fetal-Neonatal Studies Committee (CEFEN) of the Argentine Society of Pediatrics (SAP) is presented. These recommendations are original and in their elaboration, we have taken into account the best available evidence gathered by the International Liaison Committee on Resuscitation (ILCOR) as well as an exhaustive review of publications and discussions in the area to define controversial issues...
June 1, 2018: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/29730467/micro-anatomical-structure-of-the-first-spine-of-the-dorsal-fin-of-atlantic-bluefin-tuna-thunnus-thynnus-osteichthyes-scombridae
#2
Nicoletta Santamaria, Giambattista Bello, Letizia Passantino, Mariasevera Di Comite, Rosa Zupa, Chrysovalentinos Pousis, Robert Vassallo-Agius, Vincenzo Cicirelli, Gualtiero Basilone, Salvatore Mangano, Aldo Corriero
The first spine of the first dorsal fin (FS) of the Atlantic bluefin tuna (ABFT), Thunnus thynnus, is customarily used in age determination research because its transverse sections display well-defined growth marks. In this paper the FS structure was studied to explain its known dramatic age- and season-related morphological modifications, which are evidently caused by bone remodeling. Cross sections of samples from six adult ABFT were in part decalcified to be stained with histological, histochemical and immunohistochemical methods, and in part embedded in methyl-methacrylate to be either observed under a linear polarized light or microradiographed...
May 3, 2018: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://www.readbyqxmd.com/read/29699431/examining-inventions-shaping-property-the-savants-and-the-french-patent-system
#3
Jérôme Baudry
In 1791, the Loi relative aux découvertes utiles instituted a new patent system in France. Because patents were seen as the expression of the natural right of inventors, prior examination was abolished. However, only a few years after the law was passed, an unofficial examination was reinstated, and it was entrusted to the Comité Consultatif des Arts et Manufactures - a consultative body composed of prominent scientists. I analyze the political significance of the involvement of the savants in the patent system, and based on the archives of the Comité, I study the scope and practicalities of the examination process, paying close attention to the ways through which the savants of the Comité directly intervened in the writing and drawing of specifications...
April 1, 2018: History of Science; An Annual Review of Literature, Research and Teaching
https://www.readbyqxmd.com/read/29687416/mrecist-criteria-to-assess-recurrent-thyroid-carcinoma-treatment-response-after-radiofrequency-ablation-a-prospective-study
#4
S Mazzeo, R Cervelli, R Elisei, G Tarantini, C Cappelli, E Molinaro, D Galleri, L De Napoli, C Comite, R Cioni, P Vitti, D Caramella
PURPOSE: Surgical removal is recommended for recurrent thyroid carcinomas (RTCs) unable to uptake radioiodine and/or not responsive to chemotherapy. However, repeated neck dissection is difficult for surgeons. Thus, radiofrequency ablation (RFA) was proposed for RTCs. The aim of this prospective study is to assess RTC treatment response after RFA, according to well-established criteria. METHODS: Sixteen lesions in 13 patients were treated by RFA. All patients refused/were excluded from repeated surgery or other conventional therapy...
April 23, 2018: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/29675389/altered-intrinsic-functional-connectivity-of-the-primary-visual-cortex-in-youth-patients-with-comitant-exotropia-a-resting-state-fmri-study
#5
Pei-Wen Zhu, Xin Huang, Lei Ye, Nan Jiang, Yu-Lin Zhong, Qing Yuan, Fu-Qing Zhou, Yi Shao
AIM: To evaluate the differences in the functional connectivity (FC) of the primary visual cortex (V1) between the youth comitant exotropia (CE) patients and health subjects using resting functional magnetic resonance imaging (fMRI) data. METHODS: Totally, 32 CEs (25 males and 7 females) and 32 healthy control subjects (HCs) (25 males and 7 females) were enrolled in the study and underwent the MRI scanning. Two-sample t -test was used to examine differences in FC maps between the CE patients and HCs...
2018: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/29571946/nilotinib-in-locally-advanced-pigmented-villonodular-synovitis-a-multicentre-open-label-single-arm-phase-2-trial
#6
Hans Gelderblom, Claire Cropet, Christine Chevreau, Richard Boyle, Martin Tattersall, Silvia Stacchiotti, Antoine Italiano, Sophie Piperno-Neumann, Axel Le Cesne, Virginia Ferraresi, Nicolas Penel, Florence Duffaud, Philippe Cassier, Maud Toulmonde, Paolo Casali, Sophie Taieb, Séverine Guillemaut, Séverine Metzger, David Pérol, Jean-Yves Blay
BACKGROUND: Pigmented villonodular synovitis (alternatively known as diffuse-type giant cell tumour) is a rare, locally aggressive tumour driven by a specific translocation resulting in the overexpression of colony-stimulating factor 1 (CSF1). CSF1 receptor (CSF1R) inhibitors (ie, tyrosine kinase inhibitors and antibodies) induce a response in patients with pigmented villonodular synovitis. We investigated the safety and efficacy of a CSF1R tyrosine kinase inhibitor, nilotinib, in patients with locally advanced non-resectable pigmented villonodular synovitis...
March 20, 2018: Lancet Oncology
https://www.readbyqxmd.com/read/29571579/a-pan-european-ring-trial-to-validate-an-international-standard-for-detection-of-vibrio-cholerae-vibrio-parahaemolyticus-and-vibrio-vulnificus-in-seafoods
#7
R E Hartnell, L Stockley, W Keay, J-P Rosec, D Hervio-Heath, H Van den Berg, F Leoni, D Ottaviani, U Henigman, S Denayer, B Serbruyns, F Georgsson, G Krumova-Valcheva, E Gyurova, C Blanco, S Copin, E Strauch, K Wieczorek, M Lopatek, A Britova, G Hardouin, B Lombard, P In't Veld, A Leclercq, C Baker-Austin
Globally, vibrios represent an important and well-established group of bacterial foodborne pathogens. The European Commission (EC) mandated the Comite de European Normalisation (CEN) to undertake work to provide validation data for 15 methods in microbiology to support EC legislation. As part of this mandated work programme, merging of ISO/TS 21872-1:2007, which specifies a horizontal method for the detection of V. parahaemolyticus and V. cholerae, and ISO/TS 21872-2:2007, a similar horizontal method for the detection of potentially pathogenic vibrios other than V...
February 10, 2018: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/29569963/analysis-of-alterations-in-white-matter-integrity-of-adult-patients-with-comitant-exotropia
#8
Dan Li, Shenghong Li, Xianjun Zeng
Objective This study was performed to investigate structural abnormalities of the white matter in patients with comitant exotropia using the tract-based spatial statistics (TBSS) method. Methods Diffusion tensor imaging data from magnetic resonance images of the brain were collected from 20 patients with comitant exotropia and 20 age- and sex-matched healthy controls. The FMRIB Software Library was used to compute the diffusion measures, including fractional anisotropy (FA), mean diffusivity (MD), axial diffusivity (AD), and radial diffusivity (RD)...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29566654/a-quantitative-analysis-method-for-comitant-exotropia-using-video-oculography-with-alternate-cover
#9
Nohae Park, Byunggun Park, Minkyung Oh, Sunghyuk Moon, Myungmi Kim
BACKGROUND: The purpose of this study was to evaluate the efficacy of a quantitative analysis method for comitant exotropia using video-oculography (VOG) with alternate cover. METHODS: Thirty-four subjects with comitant exotropia were included. Two independent ophthalmologists measured the angle of ocular deviation using the alternate prism cover test (APCT). The video files and data of changes in ocular deviation during the alternate cover test were obtained using VOG...
March 22, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29559836/orofacial-manifestations-and-temporomandibular-disorders-of-sj%C3%A3-gren-syndrome-an-observational-study
#10
Vito Crincoli, Mariasevera Di Comite, Mariateresa Guerrieri, Rossana Patricia Rotolo, Luisa Limongelli, Angela Tempesta, Florenzo Iannone, Angela Rinaldi, Giovanni Lapadula, Gianfranco Favia
AIMS : Sjӧgren Syndrome is a disorder involving oral tissues, with xerostomia, dysgeusia, dysphagia, tooth decay, gingivitis, angular cheilitis and glossitis. Temporomandibular disorders are a generic term referred to clinical conditions involving the jaw muscles and temporomandibular joint. The aim of this study was to investigate the prevalence of oral manifestations and temporomandibular disorders (TMD) in Sjӧgren Syndrome (SS) patients compared with healthy people. METHODS : The study group included 72 SS patients (2 men, 70 women) diagnosed according to the American-European Consensus Group (AECG) Criteria...
2018: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/29507772/defining-and-evaluating-novel-procedures-for-involving-patients-in-core-outcome-set-research-creating-a-meaningful-long-list-of-candidate-outcome-domains
#11
Harriet Smith, Adele Horobin, Kathryn Fackrell, Veronica Colley, Brian Thacker, Deborah A Hall
Plain English summary: Outcome domains are aspects of a condition that matter to patients and clinicians and can be measured to assess treatment effects. For tinnitus, examples include 'tinnitus loudness' and 'ability to concentrate'. This study focuses on the first stage of agreeing which outcome domains should be measured in all clinical trials of tinnitus. Crucially, it involves identifying outcome domains, prior to a voting process. This article describes how we effectively involved patients in that study design process, and reflects on the impact of their input...
2018: Research Involvement and Engagement
https://www.readbyqxmd.com/read/29458066/volitional-voiding-of-the-bladder-following-spinal-cord-injury-validation-of-bilateral-lower-extremity-motor-function-as-a-key-predictor
#12
Christopher S Elliott, Kai B Dallas, Dimitar Zlatev, Craig V Comiter, James Crew, Kazuko Shem
PURPOSE: In many individuals with spinal cord injury a return of volitional bladder voiding is considered more important than regaining motor function. Recently a predictive model using only composite bilateral lower extremity motor scores for levels L2-S1 (range 0 to 50) was proposed by the EMSCI (European Multicenter Study about Spinal Cord Injury) group. The model showed exceptional predictive power with a AUC of 0.912. We sought to further validate the EMSCI model in a national spinal cord injury cohort...
February 17, 2018: Journal of Urology
https://www.readbyqxmd.com/read/29450486/differentiating-acute-and-subacute-vertical-strabismus-using-different-head-positions-during-the-upright-supine-test
#13
João Lemos, Adnan Subei, Mário Sousa, César Nunes, Luís Cunha, Christopher Glisson, Eric Eggenberger
Importance: Accurate clinical differentiation between skew deviation and fourth nerve palsy (4NP) is critical in the acute and subacute settings. Objective: To determine the sensitivity and specificity of the upright-supine test to detect vertical misalignment changes using different head positions for the diagnosis of acute or subacute skew deviation vs 4NP. Design, Setting, and Participants: This multicenter study enrolled consecutive patients from Coimbra University Hospital Centre, Coimbra, Portugal, and Michigan State University, Lansing, within 2 months of presenting with vertical diplopia and diagnosed as having skew deviation or acquired unilateral 4NP...
April 1, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/29362244/impact-of-early-palliative-care-on-overall-survival-of-patients-with-metastatic-upper-gastrointestinal-cancers-treated-with-first-line-chemotherapy-a-randomised-phase-iii-trial
#14
Emilie Hutt, Arlette Da Silva, Emilie Bogart, Sara Le Lay-Diomande, Diane Pannier, Stéphanie Delaine-Clisant, Marie-Cécile Le Deley, Antoine Adenis
INTRODUCTION: Palliative care (PC) has usually been offered at the end-of-life stage, although the WHO recommends providing PC as early as possible in the course of the disease. A recent study has shown that early PC (EPC) provides a more meaningful effect on quality of life and, surprisingly, on overall survival (OS) than standard treatment for patients with metastatic lung cancer. Whether EPC benefits also apply to patients with metastatic upper gastrointestinal (GI) cancers is unknown...
January 23, 2018: BMJ Open
https://www.readbyqxmd.com/read/29333846/-food-allergy-in-children-recommendations-for-diagnosis-and-treatment
#15
(no author information available yet)
Food allergy arises from a specific immune response induced by food exposure. It is the first cause of anaphylaxis in childhood. Its prevalence increased exponentially in western countries. The proteins most frequently involved in infants are cow's milk and hen's egg; and in adults, seafood. Peanuts have the same frequency in both groups. The clinical manifestations and methodology of study are directly related to the pathophysiology of the disease. Clinical history, skin prick test, patch test, and food oral challenge are essential to arrive at a correct diagnosis, that will avoid unnecessary exclusions or exposures that carry life risk...
February 1, 2018: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/29325383/-clinical-features-and-surgical-outcomes-of-acute-acquired-comitant-esotropia
#16
M Y Ren, Q Wang, L H Wang
Objective: To investigate the clinical features and surgical outcomes of patients with acute acquired concomitant esotropia (AACE) type Ⅱ(AACE-Ⅱ) and type Ⅲ (AACE-Ⅲ). Methods: Retrospective case series analysis. Medical records of consecutive patients who underwent strabismus surgery for AACE-Ⅱ and AACE-Ⅲ in Shandong Provincial Hospital affiliated to Shandong University between January 2011 and June 2016 with a minimum follow-up time of 3 months were collected. Each patient underwent a complete ophthalmological and orthoptic examination to exclude esotropia resulting from other reasons, and a systemic assessment to exclude AACE related to intracranial and systemic diseases...
December 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29302874/anti-m%C3%A3-llerian-hormone-in-pre-menopausal-females-after-ablative-radioiodine-treatment-for-differentiated-thyroid-cancer
#17
Massimo Giusti, Miranda Mittica, Paola Comite, Claudia Campana, Stefano Gay, Michele Mussap
PURPOSE: In recent years, anti-Mullerian hormone (AMH) has been considered a reliable index of ovarian reserve. There are few data on AMH values in thyroid cancer. The aim of this study was to evaluate AMH levels in pre-menopausal women with a history of low-risk thyroid cancer. METHODS: Thirty-four women (aged 40.7 ± 6.7 years) were studied 7.1 ± 0.9 years after surgery and at least one RAI treatment. A group of 23 thyroid cancer women (41.6 ± 7...
January 4, 2018: Endocrine
https://www.readbyqxmd.com/read/29282263/feasibility-of-2-d-ultrasound-shear-wave-elastography-of-fetal-lungs-in-case-of-threatened-preterm-labour-a-study-protocol
#18
Nicolas Mottet, Sébastien Aubry, Chrystelle Vidal, Guillaume Boiteux, Jean-Patrick Metz, Didier Riethmuller, Lionel Pazart, Rajeev Ramanah
INTRODUCTION: 2-D ultrasound shear wave elastography (SWE) could be considered as a new noninvasive tool for monitoring fetal lung development based on evaluation of mechanical properties during pregnancy. Interesting results are available concerning the use of SWE on developing organs, especially on premature infants and animal models. The main objective in this study is to evaluate the feasibility of 2-D SWE in human fetal lungs between 24 and 34 weeks of gestation (WG). The secondary objective is to modellise fetal lung-to-liver elastography ratio (LLE ratio) and to assess variations between normal lung and lung surfactant-enriched after a corticosteroids course indicated for a threatened preterm labour (TPL)...
December 26, 2017: BMJ Open
https://www.readbyqxmd.com/read/29234923/non-inferiority-multicenter-prospective-randomized-controlled-study-of-rectal-cancer-t-2-t-3s-superficial-n-0-m-0-undergoing-neoadjuvant-treatment-and-local-excision-tem-vs-total-mesorectal-excision-tme
#19
X Serra-Aracil, C Pericay, T Golda, L Mora, E Targarona, S Delgado, A Reina, F Vallribera, J M Enriquez-Navascues, S Serra-Pla, J C Garcia-Pacheco
PURPOSE: The standard treatment of rectal adenocarcinoma is total mesorectal excision (TME), in many cases requires a temporary or permanent stoma. TME is associated with high morbidity and genitourinary alterations. Transanal endoscopic microsurgery (TEM) allows access to tumors up to 20 cm from the anal verge, achieves minimal postoperative morbidity and mortality rates, and does not require an ostomy. The treatment of T2, N0, and M0 cancers remains controversial. Preoperative chemoradiotherapy (CRT) in association with TEM reduces local recurrence and increases survival...
February 2018: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29145257/clinical-features-of-acute-acquired-comitant-esotropia-in-the-chinese-populations
#20
Tao Fu, Jing Wang, Moran Levin, Ping Xi, Dongguo Li, Junfa Li
Acute acquired comitant esotropia (AACE) is an unusual presentation of esotropia that occurs after infancy. This study was aimed to study the clinical features and the differences between children and adult patients with AACE in the Chinese populations.This was a retrospective analysis of patients diagnosed with AACE over 4 years; 69 patients (25 females and 44 males) were identified. The patients were divided into 3 groups: < 10 year-old (n = 6, 8.7%), 10-18 year-old (n = 23, 33.3%), and ≥18 year-old (n = 40, 58...
November 2017: Medicine (Baltimore)
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