Lisa Dal Pozzo, Zhe Xu, Shan Lin, Jida Wang, Ying Wang, Ogbe Susan Enechojo, Joseph Kofi Abankwah, Yanfei Peng, Xiaoqian Chu, Huifang Zhou, Yuhong Bian
Multiple epigenetic factors play a regulatory role in maintaining the homeostasis of cutaneous components and are implicated in the aging process of the skin. They have been associated with the activation of the senescence program, which is the primary contributor to age-related decline in the skin. Senescent species drive a series of interconnected processes that impact the immediate surroundings, leading to structural changes, diminished functionality, and heightened vulnerability to infections. Geroprotective medicines that may restore the epigenetic balance represent valid therapeutic alliances against skin aging...
April 13, 2024: Biomedicine & Pharmacotherapy