keyword
MENU ▼
Read by QxMD icon Read
search

Cutaneous infection

keyword
https://www.readbyqxmd.com/read/28734749/understanding-the-main-route-of-drug-entry-in-adult-fasciola-hepatica-further-insights-into-closantel-pharmacological-activity
#1
L Ceballos, C Canton, G Cadenazzi, K Larsen, G Virkel, L Moreno, I Fairweather, C Lanusse, L Alvarez
Closantel (CLS) is highly effective against adult liver flukes after its oral or subcutaneous (sc) administration in ruminants. Trans-tegumental diffusion and oral ingestion are the two potential routes available for the entry of drugs into Fasciola hepatica. The work reported here contributes to improve the understanding of CLS pharmacology. The main goals of were: I) to determine the pattern of in vivo CLS accumulation into adult F. hepatica and relevant tissues in CLS-treated sheep; II) to investigate the influence of the physicochemical composition of the incubation medium on the CLS diffusion process into adult F...
July 19, 2017: Experimental Parasitology
https://www.readbyqxmd.com/read/28731592/arginase-activity-of-leishmania-isolated-from-patients-with-cutaneous-leishmaniasis
#2
Alireza Badirzadeh, Tahereh Taheri, Fatemeh Abedi-Astaneh, Yasaman Taslimi, Zahra Abdossamadi, Hossein Montakhab-Yeganeh, Maryam Aghashahi, Maryam Niyyati, Sima Rafati
Cutaneous leishmaniasis (CL) is one of the most important vector-borne parasitic diseases, highly endemic in Iran, and its prevalence is increasing all over the country. Arginase (ARG) activity in isolated Leishmania parasites from CL patients is yet to be explored. This study aimed to compare the ARG activity of isolated Leishmania promastigotes from CL patients with a standard strain of L. major and its influences on the disease pathogenesis. We recruited 16 confirmed CL patients from Qom province, in central Iran; after detection of Leishmania species using PCR-RFLP, we assessed the levels of ARG in the isolated promastigotes and determined the parasites' growth rate...
July 21, 2017: Parasite Immunology
https://www.readbyqxmd.com/read/28730261/post-medication-stevens-johnson-syndrome-in-a-girl-hospitalized-for-a-norovirus-and-rotavirus-infection
#3
Simona Dumitra, LuminiŢa Pilat, Alina Iftode, Ozana Nicoleta Bălan, Carmen Ramona StănculeŢ, Elena Claudia Covaci, Alexandru Fica Mircea Onel, Carmen Nicoleta Crişan
Stevens-Johnson syndrome (SJS) is a cutaneous mucosal disorder characterized by extended necrosis and detachment of the epidermis affecting <10% of the body surface, caused by drugs or infections. The authors report a case of a girl with Depakine resistant epilepsy, who develops a SJS in the third week of introducing lamotrigine. The girl also presents an acute diarrheal disease with double viral etiology - rotavirus and norovirus. The clinical image comprises polymorphic erythematous maculopapular exanthema with vesicular and bullous elements, with ulcerations and desquamations at the level of the eyelids, mouth, anogenital area and tegument denuding at the level of the abdomen and limbs...
2017: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28730222/tuberculosis-and-its-particularities-in-romania-and-worldwide
#4
Floarea Mimi NiŢu, Mihai Olteanu, Costin Teodor Streba, Gabriela Jimborean, Paraschiva Postolache, Milena Adina Man, Antigona Carmen Trofor, Roxana Maria Nemeş, Livia Dragonu, Mădălina Olteanu
Tuberculosis (TB) is a global health issue, with a rising incidence since the beginning of this century. It poses a severe mortality risk and also poses a serious economic risk as it reduces the working capacity of an individual in the most productive part of life. Developing countries face widespread tuberculosis infection - up to 95% of all cases and 98% of deaths, respectively. It is a highly contagious infectious disease caused by Mycobacterium tuberculosis (the Koch bacillus) that can be contracted from either humans or animal hosts...
2017: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28728870/outpatient-dermatology-consultation-impacts-the-diagnosis-and-management-of-pediatric-oncology-patients-a-retrospective-study
#5
Hannah Song, Sarah N Robinson, Jennifer T Huang
BACKGROUND: The impact of dermatology consultation on the care of children with oncologic conditions is unknown. OBJECTIVE: To review outpatient dermatology visits and the resulting impact on diagnosis and management of pediatric oncology patients. METHOD: Retrospective review of pediatric oncology patients with outpatient dermatology visits at a tertiary care center from 2008 to 2015. RESULTS: The most common dermatologic diagnoses in 516 patients were skin infections (21...
July 17, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28727229/volatile-organic-compound-detection-as-a-potential-means-of-diagnosing-cutaneous-wound-infections
#6
Mohammed Ashrafi, Matt Bates, Mohamed Baguneid, Teresa Alonso-Rasgado, Riina Rautemaa-Richardson, Ardeshir Bayat
Chronic cutaneous wound infections and surgical site infections (SSIs) present a huge burden on the healthcare system and can lead to increased morbidity and mortality. Current diagnostic methods of identifying and confirming infection involve culture-based and molecular methods. Both techniques are time consuming and delays commonly lead to un-targeted empirical treatment. An ideal diagnostic method would be non-invasive and highly sensitive and detect pathogenic organisms with a high degree of accuracy in order to allow targeted treatment...
July 20, 2017: Wound Repair and Regeneration
https://www.readbyqxmd.com/read/28726616/molecular-characterization-of-corynebacterium-diphtheriae-outbreak-isolates-south-africa-march-june-2015
#7
Mignon du Plessis, Nicole Wolter, Mushal Allam, Linda de Gouveia, Fahima Moosa, Genevie Ntshoe, Lucille Blumberg, Cheryl Cohen, Marshagne Smith, Portia Mutevedzi, Juno Thomas, Valentino Horne, Prashini Moodley, Moherndran Archary, Yesholata Mahabeer, Saajida Mahomed, Warren Kuhn, Koleka Mlisana, Kerrigan McCarthy, Anne von Gottberg
In 2015, a cluster of respiratory diphtheria cases was reported from KwaZulu-Natal Province in South Africa. By using whole-genome analysis, we characterized 21 Corynebacterium diphtheriae isolates collected from 20 patients and contacts during the outbreak (1 patient was infected with 2 variants of C. diphtheriae). In addition, we included 1 cutaneous isolate, 2 endocarditis isolates, and 2 archived clinical isolates (ca. 1980) for comparison. Two novel lineages were identified, namely, toxigenic sequence type (ST) ST-378 (n = 17) and nontoxigenic ST-395 (n = 3)...
August 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28725434/regression-of-multifocoal-in-transit-melanoma-metastases-after-palliative-resection-of-dominant-masses-and-2%C3%A2-years-after-treatment-with-ipilimumab
#8
Raphael B Moreira, Lana Hamieh, Evisa Gjini, Ana Lako, Katherine M Krajewski, Charles H Yoon, Patrick A Ott
BACKGROUND: Spontaneous regression of metastatic melanoma and delayed responses more than one year after treatment with ipilimumab are rarely seen. CASE PRESENTATION: Here, we present the case of a patient with in transit metastases from cutaneous melanoma on his right lower extremity who achieved complete regression of all metastatic lesions 13 months after the first of two consecutive palliative resections of dominant masses and more than two years after treatment with ipilimumab...
2017: Journal for Immunotherapy of Cancer
https://www.readbyqxmd.com/read/28725269/musculoskeletal-echinococcus-infection-as-a-rare-first-presentation-of-hydatid-disease-case-report
#9
A Marzouki, A Naam, S Abdulrazak, B Soumaré, K Lahrach, F Boutayeb
BACKGROUND: Hydatid disease (HD) is a cosmopolitan parasitosis caused by Echinococcus granulosus that can potentially affect any part of the human body. Liver and lungs are the most frequent localizations. Primary musculoskeletal hydatidosis are seldom reported in literature and their incidence is unknown. CASE PRESENTATION: We deem interesting to report a case of a primary hydatid cyst in a 25-year-old patient who presented with a painful swelling of the right elbow...
2017: Patient Safety in Surgery
https://www.readbyqxmd.com/read/28724559/identification-of-leishmania-by-maldi-tof-mass-spectrometry-using-a-free-web-based-application-and-a-dedicated-mass-spectral-library
#10
Laurence Lachaud, Anna Fernández-Arévalo, Anne Cécile Normand, Patrick Lami, Cécile Nabet, Jean Luc Donnadieu, Martine Piarroux, Farid Djenad, Carole Cassagne, Christophe Ravel, Silvia Tebar, Teresa Llovet, Denis Blanchet, Magalie Demar, Zoubir Harrat, Karim Aoun, Patrick Bastien, Carmen Muñoz, Montserrat Gállego, Renaud Piarroux
Human leishmaniasis are widely spread diseases with different clinical forms caused by about 20 species within the Leishmania genus. Leishmania species identification is relevant for therapeutic management and prognosis, especially for cutaneous and muco-cutaneous forms. Several methods are available to identify Leishmania species from culture, but they have not been standardized for the majority of the currently described species, with the exception of MultiLocus Enzyme Electrophoresis. Moreover, these techniques are expensive, time-consuming and not available in all laboratories...
July 19, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28721846/skin-fungi-from-colonization-to-infection
#11
Sybren de Hoog, Michel Monod, Tom Dawson, Teun Boekhout, Peter Mayser, Yvonne Gräser
Humans are exceptional among vertebrates in that their living tissue is directly exposed to the outside world. In the absence of protective scales, feathers, or fur, the skin has to be highly effective in defending the organism against the gamut of opportunistic fungi surrounding us. Most (sub)cutaneous infections enter the body by implantation through the skin barrier. On intact skin, two types of fungal expansion are noted: (A) colonization by commensals, i.e., growth enabled by conditions prevailing on the skin surface without degradation of tissue, and (B) infection by superficial pathogens that assimilate epidermal keratin and interact with the cellular immune system...
July 2017: Microbiology Spectrum
https://www.readbyqxmd.com/read/28720294/papillomaviruses-in-dogs-and-cats
#12
REVIEW
John S Munday, Neroli A Thomson, Jennifer A Luff
Papillomaviruses (PVs) cause disease in both dogs and cats. In dogs, PVs are thought to cause oral papillomatosis, cutaneous papillomas and canine viral pigmented plaques, whereas PVs have been rarely associated with the development of oral and cutaneous squamous cell carcinomas in this species. In cats, PVs are currently thought to cause oral papillomas, feline viral plaques, Bowenoid in situ carcinomas and feline sarcoids. Furthermore, there is increasing evidence that PVs may also be a cause of cutaneous squamous cell carcinomas and basal cell carcinomas in cats...
July 2017: Veterinary Journal
https://www.readbyqxmd.com/read/28719307/first-report-on-natural-infection-of-phlebotomus-sergenti-with-leishmania-tropica-in-a-classical-focus-of-leishmania-major-in-tunisia
#13
Kaouther Jaouadi, Jihene Bettaieb, Amira Bennour, Sadok Salem, Mohamed Ridha Rjeibi, Sana Chaabane, Rihab Yazidi, Neila Khabouchi, Adel Gharbi, Afif Ben Salah
In Tunisia, chronic cutaneous leishmaniasis due to Leishmania tropica is an important health problem. Its spreading has not been fully elucidated. Information on sandfly vectors, as well as their associated Leishmania species, is of paramount importance since vector dispersion is one of the major factors responsible for pathogen dissemination. Ninety-seven unfed females belonging to the genera Sergentomyia and Phlebotomus were collected between June and August 2015 using sticky paper traps. Polymerase chain reaction-restriction fragment length polymorphism analysis of the internal transcribed spacer 1and sequencing were used for Leishmania detection and identification...
July 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28719279/clinical-characteristics-and-prognosis-of-penicilliosis-among-human-immunodeficiency-virus-infected-patients-in-eastern-china
#14
Jun Chen, Renfang Zhang, Yinzhong Shen, Li Liu, Tangkai Qi, Zhenyan Wang, Wei Song, Yang Tang, Hongzhou Lu
AbstractTalaromyces marneffei infection is increasingly observed in people living with human immunodeficiency virus (HIV) in eastern China, a nonendemic area. This study aimed to draw the clinician's attention to this disease by presenting the clinical characteristics and prognosis of penicilliosis among HIV-infected patients from this region. We retrospectively analyzed HIV-infected patients with culture-proven T. marneffei infection admitted during January 1, 2014-December 31, 2015, at the Shanghai Public Health Clinical Center...
June 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28717286/histological-changes-in-nasolabial-cutaneous-flaps-employed-in-intraoral-reconstruction
#15
Lazaridou Maria, Dimitrakopoulos Ioannis, Vaxtsevanos Konstantinos, Iordanidis Fotis, Antoniades Konstantinos
INTRODUCTION: Nasolabial cutaneous flaps have been routinely used to reconstruct intraoral defects. The purpose of this study was to study histological changes that may occur in the skin flap as a result of its exposure to a new environment. PATIENTS AND METHODS: Thirteen patients took part in this study. Fusiform tissue specimens were obtained from the intraoral cutaneous portion of the flap. Biopsy specimens were also taken from the skin of nasolabial region and from the buccal mucosa to serve as control...
September 2017: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/28716097/regression-of-multifocoal-in-transit-melanoma-metastases-after-palliative-resection-of-dominant-masses-and-2%C3%A2-years-after-treatment-with-ipilimumab
#16
Raphael B Moreira, Lana Hamieh, Evisa Gjini, Ana Lako, Katherine M Krajewski, Charles H Yoon, Patrick A Ott
BACKGROUND: Spontaneous regression of metastatic melanoma and delayed responses more than one year after treatment with ipilimumab are rarely seen. CASE PRESENTATION: Here, we present the case of a patient with in transit metastases from cutaneous melanoma on his right lower extremity who achieved complete regression of all metastatic lesions 13 months after the first of two consecutive palliative resections of dominant masses and more than two years after treatment with ipilimumab...
July 18, 2017: Journal for Immunotherapy of Cancer
https://www.readbyqxmd.com/read/28715422/unraveling-the-genetic-diversity-and-phylogeny-of-leishmania-rna-virus-1-strains-of-infected-leishmania-isolates-circulating-in-french-guiana
#17
Sourakhata Tirera, Marine Ginouves, Damien Donato, Ignacio S Caballero, Christiane Bouchier, Anne Lavergne, Eliane Bourreau, Emilie Mosnier, Vincent Vantilcke, Pierre Couppié, Ghislaine Prevot, Vincent Lacoste
INTRODUCTION: Leishmania RNA virus type 1 (LRV1) is an endosymbiont of some Leishmania (Vianna) species in South America. Presence of LRV1 in parasites exacerbates disease severity in animal models and humans, related to a disproportioned innate immune response, and is correlated with drug treatment failures in humans. Although the virus was identified decades ago, its genomic diversity has been overlooked until now. METHODOLOGY/PRINCIPLES FINDINGS: We subjected LRV1 strains from 19 L...
July 17, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28713561/case-report-lupoid-cutaneous-leishmaniasis-mimicking-verruca-plana
#18
Emin Ozlu, Aysegul Baykan, Ozan Yaman, Ragıp Ertas, Mustafa Atasoy, Kemal Ozyurt, Abdullah Turasan, Nazan Taslıdere
Cutaneous leishmaniasis (CL) is an infectious disease caused by various species of leishmania protozoan parasites. Lupoid CL is a rare form of CL that has a stunning similarity to other granulomatous cutaneous conditions of infectious or inflammatory origin. Verruca plana, also known as a "flat wart", is a benign proliferation of the skin resulting from infection with human papilloma virus (HPV). Herein, we presented a case of lupoid CL mimicking verruca plana on the face.
2017: F1000Research
https://www.readbyqxmd.com/read/28712974/diversity-and-altitudinal-distribution-of-phlebotomine-sand-flies-diptera-psychodidae-in-visceral-leishmaniasis-endemic-areas-of-northwest-ethiopia
#19
Solomon Yared, Araya Gebreselassie, Essayas Akililu, Kebede Deribe, Meshesha Balkew, Alon Warburg, Asrat Hailu, Teshome Gebre-Michael
BACKGROUND: The Leishmaniases are caused by the protozoan parasites of the genus Leishmania and are transmitted to humans by the bite of infected female phlebotomine sand flies. Both visceral and cutaneous leishmaniases are widely distributed in different parts of Ethiopia. The aim of this study was to determine the diversity and altitudinal distribution of phlebotomine sand flies from Kafta Humera to Gondar town in northwest Ethiopia. METHODS: Seven localities were selected with distinct altitudinal variations between 550m above sea level (m a...
July 13, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28712930/disseminated-mycobacterium-kansasii-infection-with-cutaneous-lesions-in-an-immunocompetent-patient
#20
Miaomiao Zhang, Mei Feng, Jian-Qing He
We reported a case of disseminated Mycobacterium Kansasii (M. kansasii) infections involving skin tissue in a 57-year-old male farmer for recurrent fever, respiratory syndromes and skin lesions. Positive findings of syndromes, laboratory examinations and M. kansasii identified in the puncture fluid indicated the diagnosis of disseminated M. kansasii infections involving skin/soft tissue, pulmonary and mediastinal lymph nodes. After applying the standard HRE regime (isoniazid (300mg/d), rifampicin (600mg/d), and ethambutol (750mg/d)), the patient's temperature normalized and symptoms relieved gradually...
July 13, 2017: International Journal of Infectious Diseases: IJID
keyword
keyword
59095
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"