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https://www.readbyqxmd.com/read/28323437/potato-consumption-and-risk-of-colorectal-cancer-in-the-norwegian-women-and-cancer-cohort
#1
Lene A Åsli, Anja Olsen, Tonje Braaten, Eiliv Lund, Guri Skeie
Potatoes are the fourth most plentiful food crop in the world, yet the scientific literature on the health effects of potato consumption is scarce. This study aimed to investigate the association between potato consumption and the risk of colorectal cancer (CRC) among 79,778 women aged 41-70, in the Norwegian Women and Cancer study. Information on diet, lifestyle, and health was collected by questionnaire. CRC cases (n  =  912) were identified through registry linkage. Adjusted Cox proportional hazard models were used to estimate the association between potato consumption and the risk of CRC...
March 21, 2017: Nutrition and Cancer
https://www.readbyqxmd.com/read/28320200/clinical-and-biological-features-of-interval-colorectal-cancer
#2
Yu Mi Lee, Kyu Chan Huh
Interval colorectal cancer (I-CRC) is defined as a CRC diagnosed within 60 months after a negative colonoscopy, taking into account that 5 years is the "mean sojourn time." It is important to prevent the development of interval cancer. The development of interval colon cancer is associated with female sex, old age, family history of CRC, comorbidities, diverticulosis, and the skill of the endoscopist. During carcinogenesis, sessile serrated adenomas/polyps (SSA/Ps) share many genomic and colonic site characteristics with I-CRCs...
March 21, 2017: Clinical Endoscopy
https://www.readbyqxmd.com/read/28317592/long-term-prognostic-value-of-preoperative-anemia-in-patients-with-colorectal-cancer-a-systematic-review-and-meta-analysis
#3
REVIEW
M J Wilson, M van Haaren, J J Harlaar, Hee Chul Park, H J Bonjer, J Jeekel, J J Zwaginga, M Schipperus
OBJECTIVE: To evaluate the long-term prognostic factor of preoperative anemia in colorectal cancer patients. BACKGROUND: Anemia is frequently observed in colorectal cancer patients, with a case incidence of 30 to 67 percent. Besides an indicator of tumor-induced blood loss and inflammation, anemia in cancer is also suggested to be a cause of inferior outcome, possibly via worsening of tumor hypoxia. As surgery is likely to enhance anemia, the long-term prognostic value of preoperative anemia seems most interesting...
March 2017: Surgical Oncology
https://www.readbyqxmd.com/read/28302993/content-analysis-of-news-coverage-on-cancer-prevention-and-screening-in-japanese-newspapers
#4
Rina Miyawaki, Kaori Ishii, Ai Shibata, Koichiro Oka
Objectives The present study investigated articles on cancer prevention published in Japanese newspapers in 2011.Methods A content analysis of news coverage on cancer primary prevention and screening was conducted. Articles which mentioned cancer risk, prevention, and screening were extracted. For all articles on prevention, the newspaper's name, month of publication, and information source were checked. Coding variables for articles on primary prevention included causes of human cancer, risk and/or prevention, and recommended screening criteria...
2017: [Nihon Kōshū Eisei Zasshi] Japanese Journal of Public Health
https://www.readbyqxmd.com/read/28298476/a-meta-analysis-between-dietary-carbohydrate-intake-and-colorectal-cancer-risk-evidence-from-17-observational-studies
#5
Jian Huang, Guoqing Pan, Hongchao Jiang, Wenliang Li, Jian Dong, Hongbin Zhang, Xiang Ji, Zhu Zhu
   The association between dietary carbohydrate intake and colorectal cancer risk remains controversial. We therefore conducted this meta-analysis to assess the relationship between them. A literature search from the databases of Pubmed, Embase, Web of science and Medline databases were performed for available articles published in English (up to Sep 2016). Pooled relative risk (RR) with 95% confidence interval (CI) was calculated to evaluate the association between dietary carbohydrate intake and colorectal cancer risk...
March 15, 2017: Bioscience Reports
https://www.readbyqxmd.com/read/28296776/totally-laparoscopic-associating-liver-tourniquet-and-portal-vein-occlusion-for-staged-hepatectomy-combined-with-simultaneous-left-hemicolectomy-for-bilateral-liver-metastases-of-the-primary-colon-cancer-a-case-report
#6
Hong-Wei Xu, Hong-Yu Li, Fei Liu, Yong-Gang Wei, Bo Li
BACKGROUND: Resection of the liver is often limited to the insufficient future liver remnant (FLR). To address this problem, the modification surgical technique "associating liver tourniquet and portal vein occlusion for staged hepatectomy" (ALTPS) was developed and led to quick hypertrophy in a short interval. In some colorectal cancer patients with multiple and bilobar metastases, the resection of the primary is often protracted immensely to the unpredictable postoperative complications for whom is to be treated with a liver-first approach...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28295697/diagnostic-capability-of-colon-capsule-endoscopy-for-advanced-colorectal-cancer-a-pilot-study
#7
Yumiko Ota, Atsuo Yamada, Yuka Kobayashi, Ryota Niikura, Takayuki Shimpoh, Akiko Narita, Shuntaro Yoshida, Nobumi Suzuki, Hirotsugu Watabe, Yoshihiro Hirata, Soichiro Ishihara, Eiji Sunami, Toshiaki Watanabe, Kazuhiko Koike
OBJECTIVES: Colon capsule endoscopy (CCE) is a safe and effective method for detecting lesions in the colon. However, the sensitivity of CCE in detecting advanced colorectal cancer (CRC) has not been sufficiently evaluated. Therefore, the aim of this study was to assess the sensitivity of CCE in detecting advanced CRC. METHODS: Patients previously diagnosed with advanced CRC by conventional colonoscopy underwent CCE. The primary outcome measure was the sensitivity of CCE in detecting advanced CRC per patient and per lesion...
March 10, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28295283/novel-colon-cancer-susceptibility-variants-identified-from-a-genome-wide-association-study-in-african-americans
#8
Hansong Wang, Stephanie L Schmit, Christopher A Haiman, Temitope O Keku, Ikuko Kato, Julie R Palmer, David van den Berg, Lynne R Wilkens, Terrilea Burnett, David V Conti, Fredrick R Schumacher, Lisa B Signorello, William J Blot, Krista A Zanetti, Curtis Harris, Mala Pande, Sonja I Berndt, Polly A Newcomb, Dee W West, Robert Haile, Daniel O Stram, Jane C Figueiredo, Loïc Le Marchand
Genome-wide association studies (GWAS) in ethnic/racial minority populations can help to fine-map previously identified risk regions or discover new risk loci because of the genetic diversity in these populations. We conducted a GWAS of colorectal cancer (CRC) in 6,597 African Americans (1,894 cases and 4,703 controls) (Stage 1) and followed up the most promising markers in a replication set of 2,041 participants of African descent (891 cases and 1,150 controls) (Stage 2). We identified a novel variant, rs56848936 in the gene SYMPK at 19q13...
March 13, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28281559/oral-bisphosphonates-and-colorectal-cancer
#9
Emily Vogtmann, Douglas A Corley, Lucy M Almers, Chris R Cardwell, Liam J Murray, Christian C Abnet
Use of oral bisphosphonates has been associated with a decreased risk of colorectal cancer (CRC), but the association may be related to residual confounding by healthy lifestyle or body mass index (BMI). Therefore, we conducted a prospective nested case-control study within the Kaiser Permanente, Northern California health system cohort. In total, 12,505 CRC cases were individually matched to 599,534 controls. Odds ratios (OR) and 95% confidence intervals (CI) were calculated using conditional logistic regression models with adjustment for important covariates extracted from the database...
March 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28280603/family-history-of-colorectal-cancer-and-its-impact-on-survival-in-patients-with-resected-stage-iii-colon-cancer-results-from-ncctg-trial-n0147-alliance
#10
Claire L Jansson-Knodell, Nathan R Foster, Daniel J Sargent, Paul J Limburg, Stephen N Thibodeau, Thomas C Smyrk, Frank A Sinicrope, Balkrishna Jahagirdar, Richard M Goldberg, Steven R Alberts
BACKGROUND: Family history of colon cancer often portends increased risk of disease development; however, the prognostic significance of family history related to disease and survival outcomes is unclear. METHODS: To investigate the relationship between family history of colorectal cancer and survival outcomes in stage III colon cancer patients, a prospective cohort of 1,935 patients with resected stage III colon cancer enrolled in a randomized controlled trial (N0147), comparing the standard of care FOLFOX to FOLFOX with cetuximab, was studied...
February 2017: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28277895/serrated-polyps-a-concealed-but-prevalent-precursor-of-colorectal-cancer
#11
Henrik Thorlacius, Yoji Takeuchi, Takashi Kanesaka, Otto Ljungberg, Noriya Uedo, Ervin Toth
Serrated polyps have long been considered to lack malignant potential but accumulating data suggest that these lesions may cause up to one-third of all sporadic colorectal cancer. Serrated polyps are classified into three subtypes, including sessile serrated adenomas/polyps (SSA/Ps), traditional serrated adenomas (TSAs), and hyperplastic polyps (HPs). SSA/P and TSA harbour malignant potential but TSA represents only 1-2%, wheras SSA/P constitute up to 20% of all serrated lesions. HPs are most common (80%) of all serrated polyps but are considered to have a low potential of developing colorectal cancer...
March 9, 2017: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/28271094/clinical-outcomes-of-gastric-polyps-and-neoplasms-in-patients-with-familial-adenomatous-polyposis
#12
Keiko Nakamura, Satoru Nonaka, Takeshi Nakajima, Tatsuo Yachida, Seiichiro Abe, Taku Sakamoto, Haruhisa Suzuki, Shigetaka Yoshinaga, Ichiro Oda, Takahisa Matsuda, Shigeki Sekine, Yukihide Kanemitsu, Hitoshi Katai, Yutaka Saito, Seiichi Hirota
Background and study aims Familial adenomatous polyposis (FAP) is an autosomal dominant syndrome caused by a germline mutation in the adenomatous polyposis coli (APC) gene, characterized by the presence of more than 100 adenomatous polyps in the colorectum. The upper gastrointestinal tract is an extracolonic site for malignancy in patients with FAP. The frequency of death in Japanese patients with FAP because of gastric cancer is 2.8 % and that because of colon cancer is 60.6 %. Few studies have reported upper gastrointestinal diseases in patients with FAP...
March 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28270730/lymph-node-evaluation-for-colon-cancer-in-routine-clinical-practice-a-population-based-study
#13
J C Del Paggio, S Nanji, X Wei, P H MacDonald, C M Booth
BACKGROUND: Guidelines recommend that 12 or more lymph nodes (lns) be evaluated during surgical resection of colon cancer. Here, we report ln yield and its association with survival in routine practice. METHODS: Electronic records of treatment were linked to the population-based Ontario Cancer Registry to identify all patients with colon cancer treated during 2002-2008. The study population (n = 5508) included a 25% random sample of patients with stage ii or iii disease...
February 2017: Current Oncology
https://www.readbyqxmd.com/read/28270728/is-there-a-sex-effect-in-colon-cancer-disease-characteristics-management-and-outcomes-in-routine-clinical-practice
#14
J S Quirt, S Nanji, X Wei, J A Flemming, C M Booth
INTRODUCTION: The incidence of colon cancer varies by sex. Whether women and men show differences in extent of disease, treatment, and outcomes is not well described. We used a large population-based cohort to evaluate sex differences in colon cancer. METHODS: Using the Ontario Cancer Registry, all cases of colon cancer treated with surgery in Ontario during 2002-2008 were identified. Electronic records of treatment identified use of surgery and adjuvant chemotherapy...
February 2017: Current Oncology
https://www.readbyqxmd.com/read/28265285/accuracy-of-colon-capsule-endoscopy-in-detecting-colorectal-polyps-in-individuals-with-familial-colorectal-cancer-could-we-avoid-colonoscopies
#15
Cristina Alvarez-Urturi, Gloria Fernández-Esparrach, Inés Ana Ibáñez, Cristina Rodríguez De Miguel, Josep Maria Dedeu, Xavier Bessa, Henry Córdova, Maria Pellisé, Francesc Balaguer, Angels Ginés, Luis Barranco, Isis K Araujo, Montserrat Andreu, Josep Llach, Antoni Castells, Begoña González-Suarez
Background. Individuals with a family history of colorectal cancer (CRC) have an increased risk of CRC. We evaluated the diagnostic yield of CCE in the detection of lesions and also two different colon preparations. Methods. A prospective multicenter study was designed to assess CCE diagnostic yield in a cohort of asymptomatic individuals with a family history of CRC. CCE and colonoscopy were performed on the same day by 2 endoscopists who were blinded to the results of the other procedure. Results. Fifty-three participants were enrolled...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28263738/long-noncoding-rna-ccat2-can-predict-metastasis-and-a-poor-prognosis-a-meta-analysis
#16
REVIEW
Xuan Jing, Hongping Liang, Xiangrong Cui, Chongyang Han, Chonghua Hao, Kai Huo
BACKGROUND: Colon cancer associated transcript 2 (CCAT2), a novel long non-coding RNA (lncRNA), plays a key role in tumorigenesis. This meta-analysis systematically summarizes the relationship between CCAT2 and cancers. METHODS: A comprehensive, computerized literature search was conducted in PubMed, Cochrane library, Chinese National Knowledge Infrastructure, and Chinese Wan Fang database. Odds ratios (ORs), hazard ratios (HRs) and their 95% confidence interval (95% CI) were calculated to assess the effect size...
March 3, 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/28253296/a-relationship-to-survival-is-seen-by-combining-the-factors-of-mismatch-repair-status-tumor-location-and-age-of-onset-in-colorectal-cancer-patients
#17
Pan Li, Zhitao Xiao, Todd A Braciak, Qingjian Ou, Gong Chen, Fuat S Oduncu
BACKGROUND: The progression of colorectal cancer (CRC) may differ depending on the location of the tumor and the age of onset of the disease. Previous studies also suggested that the molecular basis of CRC varies with tumor location, which could affect the clinical management of patients. Therefore, we performed survival analysis looking at different age groups and mismatch repair status (MMR) of CRC patients according to primary tumor location in an attempt to identify subgroups of CRC that might help in the prognosis of disease...
2017: PloS One
https://www.readbyqxmd.com/read/28251241/shift-work-and-colorectal-cancer-risk-in-the-mcc-spain-case-control-study
#18
Kyriaki Papantoniou, Gemma Castaño-Vinyals, Ana Espinosa, Michelle C Turner, Maria Henar Alonso-Aguado, Vicente Martin, Nuria Aragonés, Beatriz Pérez-Gómez, Benito Mirón Pozo, Inés Gómez-Acebo, Eva Ardanaz, Jone M Altzibar, Rosana Peiro, Adonina Tardon, José Andrés Lorca, Maria Dolores Chirlaque, Andrés García-Palomo, Jose Juan Jimenez-Moleon, Trinidad Ierssen, Maria Ederra, Pilar Amiano, Marina Pollan, Victor Moreno, Manolis Kogevinas
Objectives Shift work that involves circadian disruption has been associated with a higher cancer risk. Most epidemiological studies to date have focused on breast cancer risk and evidence for other common tumors is limited. We evaluated the risk for colorectal cancer (CRC) in relation to shift work history in a population-based case-control study in Spain. Methods This analysis included 1626 incident CRC cases and 3378 randomly selected population controls of both sexes, enrolled in 11 regions of Spain. Sociodemographic and lifestyle information was assessed in face-to-face interviews...
March 2, 2017: Scandinavian Journal of Work, Environment & Health
https://www.readbyqxmd.com/read/28248415/colorectal-cancer-statistics-2017
#19
Rebecca L Siegel, Kimberly D Miller, Stacey A Fedewa, Dennis J Ahnen, Reinier G S Meester, Afsaneh Barzi, Ahmedin Jemal
Colorectal cancer (CRC) is one of the most common malignancies in the United States. Every 3 years, the American Cancer Society provides an update of CRC incidence, survival, and mortality rates and trends. Incidence data through 2013 were provided by the Surveillance, Epidemiology, and End Results program, the National Program of Cancer Registries, and the North American Association of Central Cancer Registries. Mortality data through 2014 were provided by the National Center for Health Statistics. CRC incidence rates are highest in Alaska Natives and blacks and lowest in Asian/Pacific Islanders, and they are 30% to 40% higher in men than in women...
March 1, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28246088/adiposity-and-cancer-at-major-anatomical-sites-umbrella-review-of-the-literature
#20
Maria Kyrgiou, Ilkka Kalliala, Georgios Markozannes, Marc J Gunter, Evangelos Paraskevaidis, Hani Gabra, Pierre Martin-Hirsch, Konstantinos K Tsilidis
Objective To evaluate the strength and validity of the evidence for the association between adiposity and risk of developing or dying from cancer.Design Umbrella review of systematic reviews and meta-analyses.Data sources PubMed, Embase, Cochrane Database of Systematic Reviews, and manual screening of retrieved references.Eligibility criteria Systematic reviews or meta-analyses of observational studies that evaluated the association between indices of adiposity and risk of developing or dying from cancer...
February 28, 2017: BMJ: British Medical Journal
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