keyword
MENU ▼
Read by QxMD icon Read
search

Colon interval cancer

keyword
https://www.readbyqxmd.com/read/28808930/hospitalization-in-the-year-preceding-major-oncologic-surgery-increases-risk-for-adverse-postoperative-events
#1
Catherine E Sharoky, Karole T Collier, Christopher J Wirtalla, Andrew J Sinnamon, Madalyn G Neuwirth, Lindsay E Kuo, Robert E Roses, Douglas L Fraker, Giorgos C Karakousis, Rachel R Kelz
BACKGROUND: Hospitalization is associated with negative clinical effects that last beyond discharge. This study aimed to determine whether hospitalization in the year before major oncologic surgery is associated with adverse outcomes. METHODS: Patients 18 years of age or older with stomach, pancreas, colon, or rectal cancer who underwent resection in California and New York (2008-2010) were included in the study. Patients with hospitalization in the year prior to oncologic resection (HYPOR) were identified...
August 14, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28806303/does-a-combination-of-laparoscopic-approach-and-full-fast-track-multimodal-management-decrease-postoperative-morbidity-a-multicenter-randomized-controlled-trial
#2
Léon Maggiori, Eric Rullier, Jérémie H Lefevre, Jean-Marc Régimbeau, Stéphane Berdah, Mehdi Karoui, Jérome Loriau, Arnaud Alvès, Eric Vicaut, Yves Panis
OBJECTIVE: The aim of this study was to assess whether association of laparoscopic approach and full fast track multimodal (FFT) management can reduce postoperative morbidity after colorectal cancer surgery, as compared to laparoscopic approach with limited fast-track program (LFT). SUMMARY OF BACKGROUND DATA: Recent advances in colorectal cancer surgery are introduction of laparoscopy and FFT implementation. METHODS: Patients eligible for elective laparoscopic colorectal cancer surgery were randomized into 2 groups: FFT or LFT care (with only early oral intake and mobilization starting on Day 1)...
August 11, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28804643/local-staging-of-sigmoid-colon-cancer-using-mri
#3
Claus Dam, Jan Lindebjerg, Anders Jakobsen, Lars Henrik Jensen, Hans Rahr, Søren Rafael Rafaelsen
BACKGROUND: An accurate radiological staging of colon cancer is crucial to select patients who may benefit from neoadjuvant chemotherapy. PURPOSE: To evaluate the diagnostic accuracy of preoperative magnetic resonance imaging (MRI) in identifying locally advanced sigmoid colon cancer, poor prognostic factors, and the inter-observer variation of the tumor apparent diffusion coefficient (ADC) values of diffusion-weighted imaging (DWI). MATERIAL AND METHODS: Using 1...
July 2017: Acta Radiologica Open
https://www.readbyqxmd.com/read/28803449/prospective-comparison-between-magnetic-resonance-imaging-and-computed-tomography-in-colorectal-cancer-staging
#4
Frederick H X Koh, Ker-Kan Tan, Lynette L S Teo, Bertrand W L Ang, Yee-Liang Thian
BACKGROUND: Diffusion-weighted (DW) imaging is a functional magnetic resonance imaging (MRI) technique that detects lesions with high cellularity, such as malignant tumours. This prospective study was performed to compare the accuracy of DW-MRI with multidetector computed tomography (MDCT) in staging of colorectal cancer. METHODS: Thirty patients with histologically proven colorectal cancer were prospectively recruited. Each patient underwent both MDCT and DW-MRI of the abdomen-pelvis for primary staging...
August 13, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28803329/childhood-body-mass-index-and-height-in-relation-to-site-specific-risks-of-colorectal-cancers-in-adult-life
#5
Britt W Jensen, Michael Gamborg, Ismail Gögenur, Andrew G Renehan, Thorkild I A Sørensen, Jennifer L Baker
As colorectal cancers have a long latency period, their origins may lie early in life. Therefore childhood body mass index (BMI; kg/m(2)) and height may be associated with adult colorectal cancer. Using a cohort design, 257,623 children from The Copenhagen School Health Records Register born from 1930 to 1972 with measured heights and weights at ages 7 to 13 years were followed for adult colon and rectal adenocarcinomas by linkage to the Danish Cancer Registry. Hazard ratios (HRs) with 95% confidence intervals (CI) were estimated by Cox proportional hazard regressions...
August 12, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28802709/sex-differences-in-cancer-risk-and-survival-a-swedish-cohort-study
#6
Cecilia Radkiewicz, Anna L V Johansson, Paul W Dickman, Mats Lambe, Gustaf Edgren
AIM: The aim of this study is to firmly delineate temporal and age trends regarding sex discrepancies in cancer risk and survival as well as quantifying the potential gain achieved by eliminating this inequality. METHODS: We performed a population-based cohort study using data on all adult incident cancer cases (n = 872,397) recorded in the Swedish Cancer Register in 1970-2014. To assess the associations between sex and cancer risk and sex and survival, male-to-female incidence rate ratios (IRRs) and excess mortality ratios (EMRs) adjusted for age and year of diagnosis were estimated using Poisson regression...
August 10, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28783542/menopausal-hormone-therapy-and-cancer-risk-an-overestimated-risk
#7
Johanna Simin, Rulla Tamimi, Jesper Lagergren, Hans-Olov Adami, Nele Brusselaers
AIM: We aimed to assess the overall cancer risk among contemporary menopausal hormone therapy (MHT) users in Sweden and the risk for different cancer types. METHODS: A nationwide Swedish population-based cohort study including all 290,186 women aged ≥ 40 years having used systemic MHT during the study period (July 2005 and December 2012), compared with the Swedish female background population. MHT ever-use (all MHT, oestrogen-only MHT [E-MHT] and oestrogen plus progestin MHT [EP-MHT]) was based on the nationwide Prescribed Drug Registry...
August 4, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28771518/cholecystectomy-can-increase-the-risk-of-colorectal-cancer-a-meta-analysis-of-10-cohort-studies
#8
Yong Zhang, Hao Liu, Li Li, Min Ai, Zheng Gong, Yong He, Yunlong Dong, Shuanglan Xu, Jun Wang, Bo Jin, Jianping Liu, Zhaowei Teng
OBJECTIVE: This study aimed to elucidate the effects of cholecystectomy on the risk of colorectal cancer (CRC) by conducting a meta-analysis of 10 cohort studies. METHODS: The eligible cohort studies were selected by searching the PubMed and EMBASE databases from their origination to June 30, 2016, as well as by consulting the reference lists of the selected articles. Two authors individually collected the data from the 10 papers. When the data showed marked heterogeneity, we used a random-effects model to estimate the overall pooled risk; otherwise, a fixed effects model was employed...
2017: PloS One
https://www.readbyqxmd.com/read/28767562/deleterious-effect-of-ras-and-evolutionary-high-risk-tp53-double-mutation-in-colorectal-liver-metastases
#9
Yun Shin Chun, Guillaume Passot, Suguru Yamashita, Maliha Nusrat, Panagiotis Katsonis, Jonathan M Loree, Claudius Conrad, Ching-Wei D Tzeng, Lianchun Xiao, Thomas A Aloia, Cathy Eng, Scott E Kopetz, Olivier Lichtarge, Jean-Nicolas Vauthey
OBJECTIVE: To assess the impact of somatic gene mutations on survival among patients undergoing resection of colorectal liver metastases (CLM). BACKGROUND: Patients undergoing CLM resection have heterogeneous outcomes, and accurate risk stratification is necessary to optimize patient selection for surgery. METHODS: Next-generation sequencing of 50 cancer-related genes was performed from primary tumors and/or liver metastases in 401 patients undergoing CLM resection...
August 1, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28763692/association-of-the-oestrogen-receptor-beta-with-hormone-status-and-prognosis-in-a-cohort-of-female-patients-with-colorectal-cancer
#10
Geriolda Topi, Roy Ehrnström, Karin Jirström, Ingrid Palmquist, Marie-Louise Lydrup, Anita Sjölander
BACKGROUND: The oestrogen receptor beta (ERβ) is the predominant oestrogen receptor in the normal colon mucosa and has been reported to exert anti-proliferative and pro-apoptotic effects. However, the role of ERβ in colorectal cancer (CRC) progression remains unclear. AIM: To investigate the role of ERβ and its association with hormone status and lifestyle indicators in a female cohort of patients with CRC. METHODS: Tissue microarrays of primary CRC tumour samples from 320 female patients were conducted with a monoclonal anti-ERβ antibody...
July 29, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28737074/intraoperative-tumor-perforation-is-associated-with-decreased-5-year-survival-in-colon-cancer-a-nationwide-database-study
#11
N S Bundgaard, V O Bendtsen, P Ingeholm, U H Seidelin, K H Jensen
BACKGROUND: It is a widely held belief that intraoperative tumor perforation in colon cancer impairs survival and causes local recurrence, although the prognostic importance remains unclear. AIM: The aim of this study was to assess the effect of unintended intraoperative tumor perforation on postoperative mortality and long-term survival. MATERIAL AND METHODS: This national cohort study was based on data from a prospectively maintained nationwide colorectal cancer database...
March 1, 2017: Scandinavian Journal of Surgery: SJS
https://www.readbyqxmd.com/read/28736986/adolescent-body-mass-index-and-risk-of-colon-and-rectal-cancer-in-a-cohort-of-1-79-million-israeli-men-and-women-a-population-based-study
#12
Zohar Levi, Jeremy D Kark, Lior H Katz, Gilad Twig, Estela Derazne, Dorit Tzur, Yaara Leibovici Weissman, Adi Leiba, Irena Lipshiez, Lital Keinan Boker, Arnon Afek
BACKGROUND: This study examined the association between the body mass index (BMI) in late adolescence and the risk of colon and rectal cancer. METHODS: This study analyzed a cohort of 1,087,358 Jewish men and 707,212 Jewish women who underwent health examinations at the ages of 16 to 19 years between 1967 and 2002 and were followed by linkage to the national cancer registry up to 2012. Cox regression was used to estimate hazard ratios (HRs) for cancer according to age- and sex-adjusted BMI percentiles from the US Centers for Disease Control and Prevention (overweight, 85th percentile to <95th percentile; obesity, ≥95th percentile)...
July 24, 2017: Cancer
https://www.readbyqxmd.com/read/28732363/meta-analysis-of-the-association-between-the-inflammatory-potential-of-diet-and-colorectal-cancer-risk
#13
Yu Fan, Xin Jin, Changfeng Man, Zhenjun Gao, Xiaoyan Wang
OBJECTIVES: The inflammatory potential of diet has been inconsistently linked to colorectal cancer (CRC) risk. This meta-analysis aimed to evaluate the association of the inflammatory potential of diet, as estimated by the dietary inflammatory index (DII) score, with CRC risk. MATERIALS AND METHODS: The PubMed and Embase databases were searched for relevant studies from inception to February 2017. All cohort and case-control studies investigating the association of the DII score with CRC risk were selected...
July 14, 2017: Oncotarget
https://www.readbyqxmd.com/read/28730678/prognosis-following-cancer-surgery-during-holiday-periods
#14
Jesper Lagergren, Fredrik Mattsson, Pernilla Lagergren
Surgery is the mainstay curative treatment in most cancer. We aimed to test the new hypothesis that cancer surgery performed during holiday periods is associated with worse long-term prognosis than for non-holiday periods. This nationwide Swedish population-based cohort study included 228,927 patients during 1997-2014 who underwent elective resectional surgery for a cancer where the annual number of resections was over 100. The 16 eligible cancer sites were grouped into 10 cancer groups. The exposure, holiday periods, was classified as wide (14-weeks) or narrow (7-weeks)...
July 21, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28723632/potential-link-between-fusobacterium-enrichment-and-dna-methylation-accumulation-in-the-inflammatory-colonic-mucosa-in-ulcerative-colitis
#15
Tomomitsu Tahara, Ichiro Hirata, Naoko Nakano, Sayumi Tahara, Noriyuki Horiguchi, Tomohiko Kawamura, Masaaki Okubo, Takamitsu Ishizuka, Hyuga Yamada, Dai Yoshida, Takafumi Ohmori, Kohei Maeda, Naruomi Komura, Hirokazu Ikuno, Yasutaka Jodai, Toshiaki Kamano, Mitsuo Nagasaka, Yoshihito Nakagawa, Tetsuya Tuskamoto, Makoto Urano, Tomoyuki Shibata, Makoto Kuroda, Naoki Ohmiya
BACKGROUND AND AIM: Fusobacterium enrichment has been associated with colorectal cancer development. Ulcerative colitis (UC) associated tumorigenesis is characterized as high degree of methylation accumulation through continuous colonic inflammation. The aim of this study was to investigate a potential link between Fusobacterium enrichment and DNA methylation accumulation in the inflammatory colonic mucosa in UC. METHODS: In the candidate analysis, inflamed colonic mucosa from 86 UC patients were characterized the methylation status of colorectal a panel of cancer related 24 genes...
June 27, 2017: Oncotarget
https://www.readbyqxmd.com/read/28717852/elevated-s100a8-protein-expression-in-breast-cancer-cells-and-breast-tumor-stroma-is-prognostic-of-poor-disease-outcome
#16
P Miller, K M Kidwell, D Thomas, M Sabel, J M Rae, D F Hayes, B I Hudson, D El-Ashry, M E Lippman
PURPOSE: Elevated S100A8 expression has been observed in cancers of the bladder, esophagus, colon, ovary, and breast. S100A8 is expressed by breast cancer cells as well as by infiltrating immune and myeloid cells. Here we investigate the association of elevated S100A8 protein expression in breast cancer cells and in breast tumor stroma with survival outcomes in a cohort of breast cancer patients. PATIENTS AND METHODS: Tissue microarrays (TMA) were constructed from breast cancer specimens from 417 patients with stage I-III breast cancer treated at the University of Michigan Comprehensive Cancer Center between 2004 and 2006...
July 17, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28713060/a-standardized-imaging-protocol-for-the-endoscopic-prediction-of-dysplasia-within-sessile-serrated-polyps-with-video
#17
David J Tate, Mahesh Jayanna, Halim Awadie, Lobke Desomer, Ralph Lee, Stephen J Heitman, Mayenaaz Sidhu, Kathleen Goodrick, Nicholas G Burgess, Hema Mehajan, Duncan McLeod, Michael J Bourke
BACKGROUND AND AIMS: Dysplasia within sessile serrated polyps (SSPs) is difficult to detect, may be mistaken for an adenoma risking incomplete resection of the background serrated tissue, and is strongly implicated in interval cancer after colonoscopy. The use of endoscopic imaging to detect dysplasia within SSP has not been systematically studied. METHODS: Consecutively detected SSP ≥8 mm in size were evaluated using a standardized imaging protocol at a tertiary endoscopy center over 3 years...
July 13, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28707461/which-patients-with-isolated-para-aortic-lymph-node-metastasis-will-truly-benefit-from-extended-lymph-node-dissection-for-colon-cancer
#18
Sung Uk Bae, Hyuk Hur, Byung Soh Min, Seung Hyuk Baik, Kang Young Lee, Nam Kyu Kim
Purpose: The prognosis of patients with colon cancer and para-aortic lymph node metastasis (PALNM) is poor. We analyzed the prognostic factors of extramesenteric lymphadenectomy for colon cancer patients with isolated PALNM. Materials and Methods: We retrospectively reviewed 49 patients with PALNM who underwent curative resection between October 1988 and December 2009. Results: In univariate analyses, the 5-year OS and DFS rates were higher in patients with ≤ 7 positive PALN (36...
July 14, 2017: Cancer Research and Treatment: Official Journal of Korean Cancer Association
https://www.readbyqxmd.com/read/28695908/long-term-colorectal-cancer-incidence-after-negative-colonoscopy-in-the-state-of-utah-the-effect-of-family-history
#19
N Jewel Samadder, Lisa Pappas, Kenneth M Boucherr, Ken R Smith, Heidi Hanson, Alison Fraser, Yuan Wan, Randall W Burt, Karen Curtin
OBJECTIVES: Colonoscopy is widely recommended for colorectal cancer (CRC) screening, but evidence to guide the optimal frequency of repeat screening examination is limited. We examined the duration and magnitude of the risk of developing CRC, following a negative colonoscopy in those at average risk and those with a first-degree family history of CRC. METHODS: A cohort of Utah residents aged 50-80 years who had a negative colonoscopy between 1 January 2001 and 31 December 2011 was identified using the Utah Population Database...
July 11, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28690452/advances-in-the-diagnosis-and-management-of-colonic-dysplasia-in-patients-with-inflammatory-bowel-disease
#20
Shirley Cohen-Mekelburg, Yecheskel Schneider, Stephanie Gold, Ellen Scherl, Adam Steinlauf
The prevalence of colorectal cancer (CRC) in inflammatory bowel disease (IBD) is estimated at 3.7%. Risk factors for CRC include more severe disease (as reflected by the extent of disease and the duration of poorly controlled disease), family history of CRC, pseudopolyps, primary sclerosing cholangitis, and male sex. In addition, both early and late onset of IBD have been shown to be risk factors in different studies. Most societal guidelines recommend initiation of surveillance colonoscopy at 8 to 10 years after IBD symptom onset, followed by subsequent surveillance in 1- to 2-year intervals...
June 2017: Gastroenterology & Hepatology
keyword
keyword
59079
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"