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https://www.readbyqxmd.com/read/29222216/development-of-forced-normalisation-psychosis-with-ethosuximide
#1
Sean Apap Mangion, Fergus Rugg-Gunn
A 50-year-old man with known multidrug resistant coexistent focal and generalised epilepsy was commenced on ethosuximide, with normalisation of his electroencephalogram and cessation of absence seizures. Within 3 weeks, he developed a rapidly worsening paranoid psychosis with visual and olfactory hallucinations. A month after the cessation of ethosuximide and concurrent treatment with olanzapine, his psychosis resolved and permitted reinitiation of ethosuximide at a lower dose without recurrence of psychotic symptoms...
December 7, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29220388/a-three-month-longitudinal-study-of-changes-in-day-night-serum-total-antioxidant-capacity-in-paranoid-schizophrenia
#2
Armando L Morera-Fumero, Estefanía Díaz-Mesa, Pedro Abreu-Gonzalez, Lourdes Fernandez-Lopez, Fernando Guillen-Pino
Free radicals and an oxidant/antioxidant imbalance have been involved in the schizophrenia pathophysiology. The total antioxidant capacity (TAC) is a measure of the antioxidant capacity of a system. Day/night changes are a biological characteristic of hormones such as melatonin or cortisol. There is little information about TAC day/night changes in schizophrenia patients. The aim of this research is to study if there are day/night changes in serum TAC levels of schizophrenia patients. Thirty-two DSM-IV schizophrenia paranoid patients were studied...
2017: PloS One
https://www.readbyqxmd.com/read/29214085/sox5-null-heterozygous-mutation-in-a-family-with-adult-onset-hyperkinesia-and-behavioral-abnormalities
#3
Michael Zech, Katharina Poustka, Sylvia Boesch, Riccardo Berutti, Tim M Strom, Wolfgang Grisold, Werner Poewe, Juliane Winkelmann
SOX5 encodes a conserved transcription factor implicated in cell-fate decisions of the neural lineage. SOX5 haploinsufficiency induced by larger genomic deletions has been linked to a recognizable pediatric syndrome combining developmental delay with intellectual disability, mild dysmorphism, inadequate behavior, and variable additional features including motor disturbances. In contrast to SOX5-involving deletions, examples of pathogenic SOX5 small coding variations are sparse in the literature and have been described only in singular cases with phenotypic abnormalities akin to those seen in the SOX5 microdeletion syndrome...
2017: Case Reports in Genetics
https://www.readbyqxmd.com/read/29203843/bisexuality-among-a-cohort-of-university-students-prevalence-and-psychological-distress
#4
Giacomo Ciocca, Caterina Solano, Giorgio Di Lorenzo, Erika Limoncin, Daniele Mollaioli, Eleonora Carosa, Alberto Collazzoni, Emiliano Santarnecchi, Emanuela Bianciardi, Cinzia Niolu, Alberto Siracusano, Alessandro Rossi, Emmanuele A Jannini
Sociocultural prejudices and pressures may impair the mental health of bisexual people. We aim to evaluate psychological status according to sexual orientation in a sample of Italian university students, with specific attention to bisexuality and its frequency. Among a recruited sample of 551 university students, we found the following percentages for sexual orientation: heterosexuals 96.9% (n = 534), homosexuals 1.1% (n = 6), bisexuals 2% (n = 11). The cross-sectional analysis for psychological symptoms, with the Symptoms Check List-90 Revised (SCL-90-R), revealed that bisexual subjects have statistically significant higher scores on some symptomatic scales compared to heterosexuals...
December 4, 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/29201791/psychological-results-of-438-patients-with-persisting-gastroesophageal-reflux-disease-symptoms-by-symptom-checklist-90-revised-questionnaire
#5
Xia Chen, Ping Li, Fei Wang, Guozhong Ji, Lin Miao, Sihong You
Aims and objectives: Gastroesophageal reflux disease (GERD) affects mental state and social activities. On the contrary, mental disorders may also play a crucial role in GERD symptoms. The purpose of the study was to analyze the data of Symptom Checklist 90-Revised (SCL-90-R) questionnaire from patients with persisting GERD and to explore the impact of psychological factors on them. Materials and methods: The patients accepted SCL-90-R questionnaire survey, following endoscopy, high-resolution manometry (HRM), and ambulatory impedance-pH monitoring...
July 2017: Euroasian Journal of Hepato-Gastroenterology
https://www.readbyqxmd.com/read/29189334/considerations-in-the-care-of-athletes-with-attention-deficit-hyperactivity-disorder
#6
George G A Pujalte, Jennifer R Maynard, McKennan J Thurston, Walter C Taylor, Mohit Chauhan
OBJECTIVES: Uncover literature pertaining to: (1) attention deficit hyperactivity disorder (ADHD) and how it impacts athletes; (2) ADHD medication effects; (3) regulations regarding ADHD medications; (4) approaches to conditions similar to, and occurring with, ADHD; and (5) use of stimulants. DATA SOURCES: MEDLINE, Embase, PsycINFO, Cochrane Database of Systematic Reviews, Ovid interface. MAIN RESULTS: ADHD can have many effects on athletes and sports participation...
November 20, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/29186861/mental-health-of-the-prison-medical-workers-pmws-and-influencing-factors-in-jiangxi-china
#7
Xiaojun Liu, Dongdong Jiang, Zhaoxun Hou, Meikun He, Yuanan Lu, Zongfu Mao
Prison medical workers (PMWs) are critically important, but they are also vulnerable to psychological problems. Currently, there is no study on examining PMWs' mental health conditions and possible influencing factors in China. Hence, we conducted this cross-sectional survey, aiming to understand the mental health status of the PMWs and related impact factors in Jiangxi province of China. We employed the Chinese version of the Symptom Checklist-90-R (SCL-90-R) to assess the mental disorders and psychological health conditions of PMWs in Jiangxi...
November 26, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29186169/epidemiology-of-severe-mental-illness-in-hunan-province-in-central-china-during-2014-2015-a-multistage-cross-sectional-study
#8
Dongxin Wang, Jing Ma, Lihong Tan, Yan Chen, Xiaosong Li, Xuefei Tian, Xuhui Zhou, Xuejun Liu
OBJECTIVE: Severe mental illness (SMI) represents major social and public health problem in China, especially in low- or middle-income regions. We aim to assess the prevalence and distribution of SMI in Hunan province in central China. METHODS: Multistage stratified random sampling methods were used to select qualified subjects in 123 districts and counties in Hunan province. 89465 individuals were randomly identified, and 72999 (81.6%) completed the supplemental 12-Item General Health Questionnaire (GHQ-12) and Cue questionnaire of psychiatric abnormal behaviors...
2017: PloS One
https://www.readbyqxmd.com/read/29182549/effects-of-group-counseling-programs-cognitive-behavioral-therapy-and-sports-intervention-on-internet-addiction-in-east-asia-a-systematic-review-and-meta-analysis
#9
Jun Liu, Jing Nie, Yafeng Wang
To evaluate the effects of group counseling programs, cognitive behavioral therapy (CBT), and sports intervention on Internet addiction (IA), a systematic search in ten databases was performed to identify eligible studies without language restrictions up to January 2017. A meta-analysis and trial sequential analysis (TSA) was performed, respectively. A total of 58 randomized controlled trials (RCTs), which included 2871 participants, were incorporated into our meta-analysis. The results showed that group counseling programs, CBT, and sports intervention could significantly reduce IA levels (group counseling program: standardized mean difference (SMD), -1...
November 28, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29181215/electroconvulsive-therapy-in-functional-hallucination-scope-and-challenges
#10
Sulochana Joshi, Rabi Shakya
Functional hallucinations are hallucinations triggered by a stimulus in the same modality and cooccur with it. They are rare in occurrence; however, their rarity has no significance as psychopathology till date. Also, very little is known about the treatment of such hallucinations. Electroconvulsive therapy (ECT) has been tested for several psychiatric illnesses and has a few relative contraindications; however, it has not previously been used in treating functional hallucinations. We report on a female patient with paranoid schizophrenia who experienced functional hallucinations continuously despite the use of adequate risperidone, which controlled other symptoms...
2017: Case Reports in Psychiatry
https://www.readbyqxmd.com/read/29179936/clinical-relevance-of-appraisals-of-persistent-psychotic-experiences-in-people-with-and-without-a-need-for-care-an-experimental-study
#11
Emmanuelle Peters, Thomas Ward, Mike Jackson, Peter Woodruff, Craig Morgan, Philip McGuire, Philippa A Garety
BACKGROUND: Cognitive models of psychosis propose that appraisals (ie, the interpretation and meaning attributed to experiences) are central to the transition from anomalous experiences to psychotic symptoms. In the Unusual Experiences Enquiry (UNIQUE) study, we investigated the role of appraisals by comparing individuals with persistent psychotic experiences without a need for care with patients and people without psychotic experiences. METHOD: Eligible participants were patients with diagnosed psychotic disorders (clinical group) and adults in the general population with persistent psychotic experiences (non-clinical group) and without psychotic experiences (controls)...
December 2017: Lancet Psychiatry
https://www.readbyqxmd.com/read/29172098/social-defeat-as-a-mediator-of-the-relationship-between-childhood-trauma-and-paranoid-ideation
#12
Jihyeon Seo, Ji Young Choi
Social defeat, the subjective experience of viewing oneself as a failure or social outsider, is associated with various psychiatric disorders. Recent studies suggest that social defeat may play an important role in the development of psychotic disorders. This study examined the role of social defeat in the relationship between childhood trauma and paranoid ideation, a symptom of psychosis, in non-psychotic mental disorders. Psychiatric patients (N = 199) completed the Korean version of the Childhood Trauma Questionnaire, the Korean version of the Defeat Scale, and Restructured Clinical Scale 6 (Ideas of Persecution) of the Korean version of the Minnesota Multiphasic Personality Inventory-2...
November 9, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29171543/state-sponsored-dental-terrorism
#13
M Kelleher
Has the state's manipulation of the NHS dental contract systems deliberately, or accidentally, had corrupting effects on the behaviours of some members of the dental profession? If the answer is 'possibly' or 'probably', then obvious questions that follow include, 'was this done deliberately' and if so, 'why'? Could this have been done for largely altruistic reasons, or was it done to achieve government control for minimum cost? Might this have been undertaken for political, financial or ideological reasons - regardless of any adverse longer term consequences for some patients or for some dental professionals? Might it have been done to take greater control of the dental profession on the grounds that all professions are a conspiracy against the laity, as the mildly paranoid George Bernard Shaw once alleged? Is it possible that some of this manipulation might have been done to help to disempower yet another profession, allegedly to 'modernise it', but perhaps to enslave it for its own reasons? Was this just another example of some statist politicians wanting to interfere in all aspects of UK society, regardless of their lack of specific understanding, or any proven expertise, in many areas? Could the state's manipulation of contracts and processes be regarded as an abuse of power by a virtual monopoly, which has been used to control a largely altruistic profession by imposing corrupting NHS dental contract systems with the most recent one involving 'units of dental activity' (UDAs)? Perhaps it was really about some politicians wanting ever more power, control or money - their usual drivers - with the dental and medical professions accidentally becoming casualties?...
November 24, 2017: British Dental Journal
https://www.readbyqxmd.com/read/29167723/the-impact-of-audio-book-on-the-elderly-mental-health
#14
Fereshteh Ameri, Naser Vazifeshenas, Abbas Haghparast
Introduction: The growing elderly population calls mental health professionals to take measures concerning the treatment of the elderly mental disorders. Today in developed countries, bibliotherapy is used for the treatment of the most prevalent psychiatric disorders. Therefore, this study aimed to investigate the effects of audio book on the elderly mental health of Retirement Center of Shahid Beheshti University of Medical Sciences. Methods: This experimental study was conducted on 60 elderly people participated in 8 audio book presentation sessions, and their mental health aspects were evaluated through mental health questionnaire (SCL-90-R)...
September 2017: Basic and Clinical Neuroscience
https://www.readbyqxmd.com/read/29167652/eye-contact-and-fear-of-being-laughed-at-in-a-gaze-discrimination-task
#15
Jorge Torres-Marín, Hugo Carretero-Dios, Alberto Acosta, Juan Lupiáñez
Current approaches conceptualize gelotophobia as a personality trait characterized by a disproportionate fear of being laughed at by others. Consistently with this perspective, gelotophobes are also described as neurotic and introverted and as having a paranoid tendency to anticipate derision and mockery situations. Although research on gelotophobia has significantly progressed over the past two decades, no evidence exists concerning the potential effects of gelotophobia in reaction to eye contact. Previous research has pointed to difficulties in discriminating gaze direction as the basis of possible misinterpretations of others' intentions or mental states...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29166226/the-origins-of-fears-of-compassion-shame-and-lack-of-safeness-memories-fears-of-compassion-and-psychopathology
#16
Marcela Matos, Joana Duarte, José Pinto-Gouveia
Empirical and clinical research suggests that some individuals find self-generating compassion and receiving compassion from others difficult and aversive. However, it is unclear how these fears of compassion are linked to early experiences and to psychopathological symptoms. This study explores the relationship between shame traumatic memories, centrality of shame memories, early memories of warmth and safeness, fears of compassion, and depression, anxiety and paranoid symptoms. Participants were 302 individuals from the general community population, who completed self-report measures of fears of compassion, shame memories, early affiliative memories, and psychopathology...
November 17, 2017: Journal of Psychology
https://www.readbyqxmd.com/read/29165678/the-genealogy-of-dementia-praecox-i-signs-and-symptoms-of-delusional-psychoses-from-1880-to-1900
#17
Kenneth S Kendler
We can trace, with high congruence, the clinical syndromes of depression and mania as described over the 20th century in psychiatric textbooks back to 1880 and to the earliest writing of Kraepelin published in 1883. However, this is not the case for Kraepelin's 2 delusional syndromes central to his overall nosology: Dementia Paranoides (later paranoid schizophrenia) and Paranoia. A detailed examination of 28 textbook descriptions of delusional psychoses from 1880 to 1900 reveals a diverse and partially overlapping set of syndromes with an admixture of symptoms and signs that would later be considered indicative of Dementia Paranoides and Paranoia...
November 19, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/29163282/from-querulous-to-suicidal-self-immolation-in-public-places-as-a-symbolic-response-to-the-feeling-of-injustice
#18
Benjamin T Lévy, Cécile Prudent, Florian Liétard, Renaud Evrard
Aim: This paper sheds light on the context that leads some querulous patients to self-immolate in front of, or into, public buildings (e.g., tribunals, city halls, and employment agencies). Method: The author defines paranoid querulousness. A psychoanalytic perspective, but also a judicial and a psychiatric point of view, over querulous claimants is presented. The links between political or social claims and self-immolation are studied. The expression of suicidal thoughts voiced by four querulous subjects is analyzed...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29141100/religiosity-and-psychological-resilience-in-patients-with-schizophrenia-and-bipolar-disorder-an-international-cross-sectional-study
#19
Y Mizuno, A Hofer, B Frajo-Apor, F Wartelsteiner, G Kemmler, S Pardeller, T Suzuki, M Mimura, W W Fleischhacker, H Uchida
OBJECTIVE: The impact of religious/spiritual activities on clinical outcomes in patients with serious mental illnesses remains controversial, which was addressed in this international cross-sectional study. METHOD: Three-hundred sixty-nine subjects were recruited from Austria (n = 189) and Japan (n = 180), consisting of 112 outpatients with paranoid schizophrenia, 120 with bipolar I disorder (DSM-IV), and 137 healthy controls. Religiosity was assessed in terms of attendance and importance of religious/spiritual activities, while resilience was assessed using the 25-item Resilience Scale...
November 15, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29122402/altered-corticostriatal-pathway-in-first-episode-paranoid-schizophrenia-resting-state-functional-and-causal-connectivity-analyses
#20
Huan Huang, Chang Shu, Jun Chen, Jilin Zou, Cheng Chen, Shihao Wu, Ling Xiao, Zhongchun Liu, Huiling Wang, Yuan Zhou, Gaohua Wang, Tianzi Jiang
Neuroimaging studies suggest the abnormal structure and function of basal ganglion may contribute to the pathophysiology of schizophrenia. However, little is investigated about the both aberrant functional and causal connectivity of striatum in first-episode paranoid schizophrenia (FEPS). Resting-state functional magnetic resonance imaging was used to characterize the functional connectivity (FC) and casual connectivity within the corticostriatal circuit in 31 patients with FEPS and 33 healthy controls. Degree centrality (DC) was used to explore the regions influenced in schizophrenia at the whole-brain level...
August 15, 2017: Psychiatry Research
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