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https://www.readbyqxmd.com/read/28345374/psychoticism-in-patients-with-panic-disorder-with-or-without-comorbid-agoraphobia
#1
Vasilios G Masdrakis, Emilia-Maria Legaki, Charalambos Papageorgiou, Manolis Markianos
OBJECTIVE: A few case-reports have previously described transient psychotic-like symptoms in non-psychotic patients with panic disorder (PD). We aimed to systematically explore whether PD patients without any current or past psychosis can be differentiated according to the severity of 'psychoticism' as a dimension, comprising clinical features such as psychotic-like experiences, increased social alienation, hostility and suspiciousness. METHODS: Sample included 35 (female = 26) medication-free, non-psychotic patients consecutively referred from our Department's Outpatient Clinic for acute symptoms of DSM-5 PD with (PDA; N = 29) or without concurrent agoraphobia...
March 27, 2017: International Journal of Psychiatry in Clinical Practice
https://www.readbyqxmd.com/read/28333778/cochlear-implant-in-severe-impaired-psychiatric-patients-a-case-series
#2
Ioana T Herisanu, Mark Praetorius, Margarete Mattern
OBJECTIVE: Psychotic disorders and intelligence deficiencies are no longer contraindications for cochlear implantation regarding the revised German guidelines from May 2012. This article aims to evaluate the outcome of patients with severe psychiatric comorbidities. Therefore the database of the Cochlear Implant Center of the University Hospital of Heidelberg was investigated. STUDY DESIGN: Retrospective case review. METHODS: We present three patients who received a cochlear implant (CI) despite a serious psychiatric disorder...
March 22, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28318838/do-paranoid-delusions-exist-on-a-continuum-with-subclinical-paranoia-a-multi-method-taxometric-study
#3
A Elahi, G Perez Algorta, F Varese, J C McIntyre, R P Bentall
BACKGROUND: There is widespread interest in whether psychosis exists on a continuum with healthy functioning. Previous research has implied that paranoia, a common symptom of psychosis, exists on a continuum but this has not been investigated using samples including both patients and non-patients and up-to-date taxometric methods. AIM: To assess the latent structure of paranoia in a diverse sample using taxometric methods. METHOD: We obtained data from 2836 participants, including the general population as well as at-risk mental state and psychotic patients using the P-scale of the Paranoia and Deservedness Scale...
March 17, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28303445/interactive-effect-of-parent-and-adolescent-psychiatric-symptoms-on-substance-use-among-adolescents-in-community-treatment
#4
Lourah M Kelly, Sara J Becker, Jennifer C Wolff, Hannah Graves, Anthony Spirito
Both adolescent and parent psychiatric symptoms are well-established risk factors for adolescent substance use (SU), but the ways that these symptoms interact are not well understood. This study examined the interactive effects of parent and adolescent psychiatric symptoms on adolescent frequency of alcohol and marijuana use, over and above the effects of parental SU. Seventy adolescents presenting to a community mental health center (CMHC) participated. Parent and adolescent psychiatric symptoms were measured with the brief symptom inventory (BSI) and child behavior checklist (CBCL), respectively...
March 16, 2017: Community Mental Health Journal
https://www.readbyqxmd.com/read/28288440/schizophrenia-spectrum-personality-disorders-in-psychometrically-identified-schizotypes-at-two-year-follow-up
#5
P Kevin Bolinskey, Elizabeth A Smith, Kelly M Schuder, Dianna Cooper-Bolinskey, Kevin R Myers, Daniel V Hudak, Alison V James, Helen K Hunter, Jonathan H Novi, Janice P Guidi, Yelena Gonzalez, Erin F McTiernan, Kaitlin M Arnold, Carina A Iati, Irving I Gottesman
Earlier (Bolinskey et al., 2015), we reported that psychometrically identified schizotypes displayed greater symptom levels and higher incidences of schizophrenia spectrum (schizotypal, schizoid, paranoid, and avoidant) personality disorders (PDs). In this study, 49 schizotypes and 39 matched controls participated in follow-up assessments after two years. Participants were previously identified as schizotypes or controls based on scores on the Chapman Psychosis Proneness Scales (CPPS), and were interviewed at baseline and follow-up with the Personality Disorder Interview for DSM-IV (PDI-IV)...
March 8, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28265458/diagnosing-the-frontal-variant-of-alzheimer-s-disease-a-clinician-s-yellow-brick-road
#6
REVIEW
Russell P Sawyer, Federico Rodriguez-Porcel, Matthew Hagen, Rhonna Shatz, Alberto J Espay
BACKGROUND: Disruption of the frontal lobes and its associated networks are a common consequence of neurodegenerative disorders. Given the wide range of cognitive, behavioral and motor processes in which the frontal lobes are involved, there can be a great variety of manifestations depending on the pathology distribution. The most common are the behavioral variant of frontotemporal dementia (bvFTD) and the frontal variant of Alzheimer's disease (fvAD), which are particularly challenging to disentangle...
2017: Journal of Clinical Movement Disorders
https://www.readbyqxmd.com/read/28252601/-specificity-of-spatial-organization-of-evoked-eeg-rhythms-in-patients-with-paranoid-schizophrenia
#7
V K Bochkarev, A V Kirenskaya, S V Solnceva, A A Tkachenko
AIM: The study aimed at analyzing the spatial patterns of evoked event-related oscillations in patients with paranoid schizophrenia and their relationship with clinical symptoms of disease. MATERIAL AND METHODS: Evoked delta, theta, alpha, beta, and gamma rhythms in response to target auditory stimulus in an oddball paradigm were studied in 21 schizophrenic patients and 22 healthy subjects. The independent spatial patterns were revealed within each of the frequency range using the principal component analysis...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28229240/microglia-in-the-dorsal-raphe-nucleus-plays-a-potential-role-in-both-suicide-facilitation-and-prevention-in-affective-disorders
#8
Ralf Brisch, Johann Steiner, Christian Mawrin, Marta Krzyżanowska, Zbigniew Jankowski, Tomasz Gos
An involvement of the central serotonergic system has constantly been reported in the pathogenesis of suicide. The dorsal raphe nucleus (DRN) is the main source of serotonergic innervation of forebrain limbic structures disturbed in suicidal behaviour, in which an abnormal microglia reaction seems to play a role. In our present study, the density of microglia immunostained for the HLA-DR antigen was evaluated in the DRN. These analyses were carried out on paraffin-embedded brains from 24 suicidal and 21 non-suicidal patients; among them, 27 depressed (15 major depressive disorder and 12 bipolar disorder) and 18 schizophrenia (9 residual and 9 paranoid) patients and 22 matched controls without mental disorders...
February 22, 2017: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/28228737/schizophrenia-associated-with-epileptiform-discharges-without-seizures-successfully-treated-with-levetiracetam
#9
Dominique Endres, Evgeniy Perlov, Bernd Feige, Dirk-Matthias Altenmüller, Nils Venhoff, Ludger Tebartz van Elst
BACKGROUND: Schizophrenia-like disorders can be divided into endogenic or primary, idiopathic, polygenetic forms, and different secondary, organic subgroups [e.g., (para)epileptic, immunological, degenerative]. Epileptic and paraepileptic explanatory approaches have a long tradition due to the high rate of electroencephalography (EEG) alterations in patients with schizophrenia. CASE PRESENTATION: We present the case of a 23-year-old female patient suffering, since the age of 14 years, from a fluctuating paranoid-hallucinatory syndrome with formal thought disorder, fear, delusions of persecution, auditory, visual, and tactile hallucinations, as well as negative and cognitive symptoms...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28210229/longitudinal-associations-between-posttraumatic-stress-disorder-severity-and-personality-disorder-features-among-female-rape-survivors
#10
Michelle J Bovin, Erika J Wolf, Patricia A Resick
This study evaluated how change in posttraumatic stress disorder (PTSD) symptoms was associated with residualized change in comorbid personality disorder (PD) features and vice versa over the course of 5-10 years. The sample was comprised of 79 female rape survivors who met criteria for PTSD and who were a part of a larger study examining the effects of trauma-focused therapy. PTSD was assessed with the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) version of the Clinician-Administered PTSD Scale [CAPS-IV (1)] and PD features were assessed with the DSM-IV dimensional PD scales on the Schedule for Non-adaptive and Adaptive Personality [SNAP (2)]...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28188811/day-night-changes-in-serum-s100b-protein-concentrations-in-acute-paranoid-schizophrenia
#11
Armando L Morera-Fumero, Estefanía Díaz-Mesa, Pedro Abreu-Gonzalez, Lourdes Fernandez-Lopez, Maria Del Rosario Cejas-Mendez
There are day/night and seasonal changes in biological markers such as melatonin and cortisol. Controversial changes in serum S100B protein levels have been described in schizophrenia. We aim studying whether serum S100B levels present day/night variations in schizophrenia patients and whether S100B levels are related to psychopathology. Sixty-five paranoid schizophrenic inpatients participated in the study. Psychopathology was assessed with the Positive and Negative Syndrome Scale (PANSS) at admission and discharge...
April 3, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28183401/stigma-and-psychological-distress-in-suicide-survivors
#12
Paolo Scocco, Antonio Preti, Stefano Totaro, Alessandro Ferrari, Elena Toffol
BACKGROUND: Suicide bereavement is frequently related to clinically significant psychological distress and affected by stigma. This study was designed to evaluate the relationship between psychological distress by psychopathological domains and stigma, in a sample of individuals bereaved by suicide (suicide survivors). METHODS: The data were collected between January 2012 and December 2014 and included information on sociodemographic variables (gender, age, marital status and education level) and responses to the Stigma of Suicide Survivor scale (STOSSS) and the Brief Symptom Inventory (BSI)...
March 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28179386/cognitive-impairment-and-depressive-symptoms-coexisting-in-an-elderly-man
#13
Ruziana Masiran, Nicholas Tze Ping Pang
We report a case of a man aged 67 years presenting with recent depressive symptoms and paranoid ideations in addition to 1-year cognitive impairment. He has vascular risk factors and family history of memory loss. An episode of depression 2 decades ago resolved spontaneously but was followed by occupational decline. On mental state examination, he denied having depressed mood, hallucinations or delusions, but there were prominent word-finding difficulties and impaired attention and concentration.
February 8, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28152470/effectiveness-of-electroconvulsive-therapy-in-patients-with-treatment-resistant-schizophrenia-a-retrospective-study
#14
Sandeep Grover, Subho Chakrabarti, Nandita Hazari, Ajit Avasthi
This study aimed to evaluate the effectiveness of electroconvulsive therapy (ECT) among patients with treatment resistant schizophrenia (TRS). Records of patients who had received ECT were reviewed to identify patients with TRS who were administered ECT in combination with clozapine. Socio-demographic, clinical data and ECT details were extracted. The most common diagnosis was of paranoid schizophrenia (49%) followed by undifferentiated schizophrenia (36%). A-fifth (22%) of the patients were judged to have poor response to clozapine...
March 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28147290/personality-traits-and-psychotic-symptoms-in-recent-onset-of-psychosis-patients
#15
Julia Sevilla-Llewellyn-Jones, Pablo Cano-Domínguez, Antonia de-Luis-Matilla, Inmaculada Peñuelas-Calvo, Alberto Espina-Eizaguirre, Berta Moreno-Kustner, Susana Ochoa
OBJECTIVE: Personality in patients with psychosis, and particularly its relation to psychotic symptoms in recent onset of psychosis (ROP) patients, is understudied. The aims of this research were to study the relation between dimensional and categorical clinical personality traits and symptoms, as well as the effects that symptoms, sex and age have on clinically significant personality traits. METHODS: Data for these analyses were obtained from 94 ROP patients. The Millon Clinical Multiaxial Inventory and the Positive and Negative Syndrome Scale were used to assess personality and symptoms...
January 14, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28130990/psychiatric-symptoms-quality-of-life-and-hiv-status-among-people-using-opioids-in-saint-petersburg-russia
#16
Alethea Desrosiers, Elena Blokhina, Evgeny Krupitsky, Edwin Zvartau, Richard Schottenfeld, Marek Chawarski
BACKGROUND: The Russian Federation is experiencing a very high rate of HIV infection among people who inject drugs (PWID). However, few studies have explored characteristics of people with co-occurring opioid use disorders and HIV, including psychiatric symptom presentations and how these symptoms might relate to quality of life. The current study therefore explored a.) differences in baseline psychiatric symptoms among HIV+ and HIV- individuals with opioid use disorder seeking naltrexone treatment at two treatment centers in Saint Petersburg, Russia and b...
March 1, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28126575/low-levels-of-serum-total-antioxidant-capacity-and-presence-at-admission-and-absence-at-discharge-of-a-day-night-change-as-a-marker-of-acute-paranoid-schizophrenia-relapse
#17
Armando L Morera-Fumero, Estefanía Díaz-Mesa, Pedro Abreu-Gonzalez, Lourdes Fernandez-Lopez, Maria Del Rosario Cejas-Mendez
BACKGROUND: An oxidant-antioxidant system dysregulation has been described as a schizophrenia pathophysiological base. The total antioxidant capacity (TAC) is one measure of the antioxidant capacity of a system. Day/night concentration changes is a biological characteristic of hormones such as melatonin or cortisol. There is no information about TAC day/night changes in schizophrenia. AIMS: Studying the existence of a day/night TAC change in schizophrenia. METHOD: Forty-three DSM-IV paranoid schizophrenia inpatients participated in the study...
March 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28124444/preliminary-study-of-effects-on-paranoia-ideation-and-jumping-to-conclusions-in-the-context-of-group-treatment-of-anxiety-disorders-in-young-people
#18
Laura Giusti, Donatella Ussorio, Anna Salza, Maurizio Malavolta, Annalisa Aggio, Valeria Bianchini, Massimo Casacchia, Rita Roncone
BACKGROUND: People with anxiety disorders tend to focus on unpleasant and threatening stimuli. Our aims were to evaluate: (1) the presence of paranoid ideation, and the jumping to conclusions (JTC) bias in young suffering from an anxiety disorder and (2) the effectiveness of a cognitive-behavioural intervention (CBT) to manage anxiety combined with 2 modules to reduce the JTC bias. METHODS: Psychopathology, social functioning, metacognition and the JTC bias were investigated in 60 subjects, randomly assigned to the experimental CBT group + treatment-as-usual (TAU) (n = 35) or to a wait-list group (n = 25) receiving only TAU...
January 26, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/28101905/mapping-the-road-from-childhood-adversity-to-personality-disorder-the-role-of-unresolved-states-of-mind
#19
Antonella Cirasola, Saul Hillman, Peter Fonagy, Marco Chiesa
Childhood adversity has been found to be an important aetiological factor in the development of personality disorder (PD) in several studies. However, the role of disorganized attachment with unresolved mental states for traumatic experiences requires further investigation. This study explores the relationship between childhood adversities, unresolved states of mind, PD diagnosis and psychiatric distress. Two hundred forty-five adult participants, 124 from a clinical PD group and 121 non-psychiatric controls were assessed using the Structured Clinical Interview for DSM-IV, the Cassel Baseline Questionnaire, the Symptom Checklist-90-R and the Adult Attachment Interview, in order to ascertain presence of PD, childhood adversity, level of psychiatric distress and unresolved states of mind...
January 19, 2017: Personality and Mental Health
https://www.readbyqxmd.com/read/28072646/clozapine-treatment-of-olanzapine-induced-tardive-dyskinesia-a-case-report
#20
Dinesh Sangroula, Inderpreet Virk, Wali Mohammad, David A Kahn
Tardive dyskinesias (TD) are serious, often irreversible side effects of dopamine blocking agents, most commonly first-generation antipsychotics. No definitive treatment exists, with different interventions showing inconsistent results. We report a case of TD presenting after 12 years of olanzapine therapy in a 66-year-old Hispanic male with paranoid schizophrenia. The TD symptoms were successfully treated within a few weeks by switching to clozapine. Two cases of olanzapine-induced TD treated with clozapine have previously been reported, but in those cases, the symptom onset was quicker, ranging from a few months to a few years after initiation of olanzapine therapy, and the treatment response was relatively slower...
January 2017: Journal of Psychiatric Practice
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