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Transcutaneous direct temporal stimulation

A Perrotta, M Bolla, M G Anastasio, M Serrao, G Sandrini, F Pierelli
OBJECTIVE: Transcutaneous spinal direct current stimulation (tsDCS) modulates spinal cord pain pathways. The study is aimed to clarify the neurophysiology of the tsDCS-induced modulation of the spinal cord pain processing by evaluating the effect of the tsDCS on temporal summation threshold (TST) of the nociceptive withdrawal reflex (NWR). METHODS: In a randomized, double-blind, crossover study the effects of anodal, cathodal and sham tsDCS (2 mA, 15 min) applied on the skin overlying the thoracic spinal cord were investigated in 10 healthy subjects...
January 2016: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
Xiao-Hui Xiang, Ying-Mao Chen, Jin-Ming Zhang, Jia-He Tian, Ji-Sheng Han, Cai-Lian Cui
Although systematic studies have demonstrated that acupuncture or electroacupuncture (EA) analgesia is based on their accelerating endogenous opioid release to activate opioid receptors and that EA of different frequencies is mediated by different opioid receptors in specific areas of the central nervous system, there is little direct, real-time evidence to confirm this in vivo. The present study was designed to investigate the effects of transcutaneous electrical acupoint stimulation (TEAS), an analogue of EA, at low and high frequencies on μ-opioid receptor (MOR) availability in the brain of rhesus monkeys...
May 2014: Journal of Neuroscience Research
James W Ibinson, Keith M Vogt
UNLABELLED: The temporal dynamics of the blood oxygen level-dependent (BOLD) signal, especially for painful stimulations, is not completely understood. In this study, the BOLD signal response to a long painful electrical stimulation (a continuous painful stimulation of 2 minutes) is directly compared to that of a short painful stimulation (four 30-second periods of painful stimulation interleaved with 30-second rest) in an effort to further probe the relationship between the temporal dynamics of the BOLD signal during constant-intensity pain stimulation...
December 2013: Journal of Pain: Official Journal of the American Pain Society
Thomas Kraus, Olga Kiess, Katharina Hösl, Pavel Terekhin, Johannes Kornhuber, Clemens Forster
BACKGROUND: It has recently been shown that electrical stimulation of sensory afferents within the outer auditory canal may facilitate a transcutaneous form of central nervous system stimulation. Functional magnetic resonance imaging (fMRI) blood oxygenation level dependent (BOLD) effects in limbic and temporal structures have been detected in two independent studies. In the present study, we investigated BOLD fMRI effects in response to transcutaneous electrical stimulation of two different zones in the left outer auditory canal...
September 2013: Brain Stimulation
C C Liu, P Franaszczuk, N E Crone, C Jouny, F A Lenz
Two decades of functional imaging studies have demonstrated pain-related activations of primary somatic sensory cortex (S1), parasylvian cortical structures (PS), and medial frontal cortical structures (MF), which are often described as modules in a "pain network." The directionality and temporal dynamics of interactions between and within the cortical and thalamic modules are uncertain. We now describe our studies of these interactions based upon recordings of local field potentials (LFPs) carried out in an epilepsy monitoring unit over the one week period between the implantation and removal of cortical electrodes during the surgical treatment of epilepsy...
2011: Frontiers in Integrative Neuroscience
Sven Vanneste, Farah Focquaert, Paul Van de Heyning, Dirk De Ridder
Tinnitus is an ongoing phantom percept. It has been demonstrated that bifrontal transcranial direct current stimulation (tDCS) can reduce tinnitus. In this study, one group of patients reported a substantial improvement in their tinnitus perception, whereas another group described minor or no beneficial effect at all. The objective was to verify whether the activity and connectivity of the resting brain is different for people who will respond to bifrontal tDCS for tinnitus in comparison with non-responders...
April 2011: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
Berthold Langguth, Dirk de Ridder, John L Dornhoffer, Peter Eichhammer, Robert L Folmer, Elmar Frank, Felipe Fregni, Christian Gerloff, Eman Khedr, Tobias Kleinjung, Michael Landgrebe, Scott Lee, Jean-Pascal Lefaucheur, Alain Londero, Renata Marcondes, Aage R Moller, Alvaro Pascual-Leone, Christian Plewnia, Simone Rossi, Tanit Sanchez, Philipp Sand, Winfried Schlee, Dipl Pysch, Thomas Steffens, Paul van de Heyning, Goeran Hajak
BACKGROUND: Tinnitus affects 10% of the population, its pathophysiology remains incompletely understood, and treatment is elusive. Functional imaging has demonstrated a relationship between the intensity of tinnitus and the degree of reorganization in the auditory cortex. Experimental studies have further shown that tinnitus is associated with synchronized hyperactivity in the auditory cortex. Therefore, targeted modulation of auditory cortex has been proposed as a new therapeutic approach for chronic tinnitus...
July 2008: Brain Stimulation
Yaron Har-Shai, Tamir Gil, Issa Metanes, Daniel Labbé
BACKGROUND: Facial paralysis is a significant functional and aesthetic handicap. Facial reanimation is performed either by two-stage microsurgical methods or by regional one-stage muscle pedicle flaps. Labbé has modified and improved the regional muscle pedicle transfer flaps for facial reanimation (i.e., the lengthening temporalis myoplasty procedure). This true myoplasty technique is capable of producing a coordinated, spontaneous, and symmetrical smile. An intraoperative electrical stimulation of the temporal muscle is proposed to simulate the smile of the paralyzed side on the surgical table...
July 2010: Plastic and Reconstructive Surgery
T Kraus, K Hösl, O Kiess, A Schanze, J Kornhuber, C Forster
UNLABELLED: Direct vagus nerve stimulation (VNS) has proved to be an effective treatment for seizure disorder and major depression. However, since this invasive technique implies surgery, with its side-effects and relatively high financial costs, a non-invasive method to stimulate vagal afferences would be a great step forward. We studied effects of non-invasive electrical stimulation of the nerves in the left outer auditory canal in healthy subjects (n = 22), aiming to activate vagal afferences transcutaneously (t-VNS)...
2007: Journal of Neural Transmission
Claudia Spadavecchia, Lars Arendt-Nielsen, Luciano Spadavecchia, Martina Mosing, Ulricke Auer, Renè van den Hoven
OBJECTIVE: To assess the effects of a single intravenous dose of butorphanol (0.1 mg kg(-1)) on the nociceptive withdrawal reflex (NWR) using threshold, suprathreshold and repeated subthreshold electrical stimuli in conscious horses. STUDY DESIGN: 'Unblinded', prospective experimental study. ANIMALS: Ten adult horses, five geldings and five mares, mean body mass 517 kg (range 487-569 kg). METHODS: The NWR was elicited using single transcutaneous electrical stimulation of the palmar digital nerve...
January 2007: Veterinary Anaesthesia and Analgesia
G Cruccu, M Inghilleri, A Berardelli, G Pauletti, C Casali, P Coratti, G Frisardi, P D Thompson, M Manfredi
Two patients aged 21 and 50 years presented with facial hemiatrophy and unilateral spasms of the masticatory muscles. Masticatory muscle biopsy showed normal findings in both patients and facial skin biopsy specimens only showed atrophy, although morphoea (localised facial scleroderma) had been diagnosed nine years previously in the second patient. The involuntary movements consisted of brief twitches and prolonged contractions clinically and electromyographically similar to those of hemifacial spasm and cramps...
January 1994: Journal of Neurology, Neurosurgery, and Psychiatry
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