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https://www.readbyqxmd.com/read/27773779/a-closer-look-at-travellers-infections-abroad-finnish-nationwide-data-with-incidences-2010-to-2012
#1
Heli Siikamäki, Pia Kivelä, Mikael Fotopoulos, Anu Kantele
BACKGROUND: Although infections represent the most common health problem of travellers abroad, data on morbidity and incidences of various infections are scarce. METHOD: Data on infections of Finnish travellers during 2010 to 2012 were retrieved from the database of SOS International, an assistance organization covering 95% of Finns requiring aid abroad. The study included 30,086 cases. For incidence calculation, the data were linked to the numbers of Finns visiting these regions during the same period as recorded by the Official Statistics of Finland...
October 20, 2016: Travel Medicine and Infectious Disease
https://www.readbyqxmd.com/read/27759360/a-relook-of-cefuroxime-in-community-infections-an-option-still-beneficial
#2
V R Badhwar, S Ganapathy, P P Prabhudesai, N K Tulara, A Y Varaiya, D Vyas
In community and family practice, infections are a common OPD presentation. In the management of common bacterial infections seen in community especially RTI, UTI, SSTI; cefuroxime a second generation cephalosporin with a broad spectrum of activity can be used for empirical treatment. To know current place of cefuroxime in the management of infections, physicians, surgeons, microbiologist, chest physician, gynecologist and pediatrician came together to discuss and debate their experience with cefuroxime and its place in today's world...
July 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27619037/evaluation-of-vitamin-d-levels-in-children-with-primary-epistaxis
#3
Habip Almis, Ibrahim Hakan Bucak, Muhammed Nebi Caliskan, Mehmet Turgut
OBJECTIVE: This study aimed to investigate whether there is a relationship between 25-hydroxy vitamin D [25(OH)D 3] values and incidences of primary epistaxis among children. METHODS: A total of 42 cases and 55 matched controls were included in our study. The study group and control group were well matched for age and gender. Age, gender, activated partial thromboplastin time (APTT) with reference to the international normalized ratio (INR), prothrombin time (PT), and 25(OH)D 3, parathormone (PTH), alkaline phosphatase (ALP), calcium (Ca), magnesium (Mg), and phosphorus (P) values were recorded for each participant...
October 2016: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/27559830/update-interim-guidance-for-the-evaluation-and-management-of-infants-with-possible-congenital-zika-virus-infection-united-states-august-2016
#4
Kate Russell, Sara E Oliver, Lillianne Lewis, Wanda D Barfield, Janet Cragan, Dana Meaney-Delman, J Erin Staples, Marc Fischer, Georgina Peacock, Titilope Oduyebo, Emily E Petersen, Sherif Zaki, Cynthia A Moore, Sonja A Rasmussen
CDC has updated its interim guidance for U.S. health care providers caring for infants born to mothers with possible Zika virus infection during pregnancy (1). Laboratory testing is recommended for 1) infants born to mothers with laboratory evidence of Zika virus infection during pregnancy and 2) infants who have abnormal clinical or neuroimaging findings suggestive of congenital Zika syndrome and a maternal epidemiologic link suggesting possible transmission, regardless of maternal Zika virus test results...
2016: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/27139474/systematic-review-of-factors-associated-with-antibiotic-prescribing-for-respiratory-tract-infections
#5
Rachel McKay, Allison Mah, Michael R Law, Kimberlyn McGrail, David M Patrick
Antibiotic use is a modifiable driver of antibiotic resistance. In many circumstances, antibiotic use is overly broad or unnecessary. We systematically assessed factors associated with antibiotic prescribing for respiratory tract infections (RTI). Studies were included if they used actual (not self-reported or intended) prescribing data, assessed factors associated with antibiotic prescribing for RTIs, and performed multivariable analysis of associations. We searched Medline, Embase, and International Pharmaceutical Abstracts using keyword and MeSH (medical subject headings) search terms...
July 2016: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/26636031/integrated-targeted-and-non-targeted-analysis-of-water-sample-extracts-with-micro-scale-uhplc-ms
#6
Dominik Deyerling, Karl-Werner Schramm
A sensitive method is introduced to detect selected pharmaceutical residues and polar pesticides with UHPLC-MS in water samples of different origin. Active or passive water sampling was combined with a laboratory solid-phase extraction cleanup and stable isotope dilution analysis. Recovery experiments demonstrated that the internal standard correction performed well for the compensation of matrix effects. Besides, the original targeted analysis approach was expanded by non-target analysis of the samples with only one more consecutive injection run needed...
2015: MethodsX
https://www.readbyqxmd.com/read/26619031/the-rationale-for-patient-reported-outcomes-surveillance-in-cancer-and-a-reproducible-method-for-achieving-it
#7
Tenbroeck G Smith, Kathleen M Castro, Alyssa N Troeschel, Neeraj K Arora, Joseph Lipscomb, Shelton M Jones, Katherine A Treiman, Connie Hobbs, Ryan M McCabe, Steven B Clauser
Patient-reported outcomes (PROs) measure quality of life, symptoms, patient functioning, and patient perceptions of care; they are essential for gaining a full understanding of cancer care and the impact of cancer on people's lives. Repeatedly captured facility-level and/or population-level PROs (PRO surveillance) could play an important role in quality monitoring and improvement, benchmarking, advocacy, policy making, and research. This article describes the rationale for PRO surveillance and the methods of the Patient Reported Outcomes Symptoms and Side Effects Study (PROSSES), which is the first PRO study to use the American College of Surgeons Commission on Cancer's Rapid Quality Reporting System to identify patients and manage study data flow...
February 1, 2016: Cancer
https://www.readbyqxmd.com/read/26376123/targeted-proteomics-of-human-metapneumovirus-in-clinical-samples-and-viral-cultures
#8
Matthew W Foster, Geoff Gerhardt, Lynda Robitaille, Pier-Luc Plante, Guy Boivin, Jacques Corbeil, M Arthur Moseley
The rapid, sensitive, and specific identification of infectious pathogens from clinical isolates is a critical need in the hospital setting. Mass spectrometry (MS) has been widely adopted for identification of bacterial pathogens, although polymerase chain reaction remains the mainstay for the identification of viral pathogens. Here, we explored the capability of MS for the detection of human metapneumovirus (HMPV), a common cause of respiratory tract infections in children. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) sequencing of a single HMPV reference strain (CAN97-83) was used to develop a multiple reaction monitoring (MRM) assay that employed stable isotope-labeled peptide internal standards for quantitation of HMPV...
October 20, 2015: Analytical Chemistry
https://www.readbyqxmd.com/read/26358916/epidemiology-of-healthcare-associated-infections-in-germany-nearly-20-years-of-surveillance
#9
C Schröder, F Schwab, M Behnke, A-C Breier, F Maechler, B Piening, M Dettenkofer, C Geffers, P Gastmeier
OBJECTIVE: To describe the epidemiology of healthcare-associated infections (HAI) in hospitals participating in the German national nosocomial infections surveillance system (KISS). METHOD: The epidemiology of HAI was described for the surveillance components for intensive care units (ITS-KISS), non-ICUs (STATIONS-KISS), very low birth weight infants (NEO-KISS) and surgical site infections (OP-KISS) in the period from 2006 to 2013. In addition, risk factor analyses were performed for the most important infections of ICU-KISS, NEO-KISS and OP-KISS...
October 2015: International Journal of Medical Microbiology: IJMM
https://www.readbyqxmd.com/read/26341275/asthma-flare-up-diary-for-young-children-to-monitor-the-severity-of-exacerbations
#10
Francine M Ducharme, Megan E Jensen, Morton J Mendelson, Patricia C Parkin, Eve Desplats, Xun Zhang, Robert Platt
BACKGROUND: Few instruments exist to ascertain the severity of a preschool-aged child's asthma exacerbations managed at home. OBJECTIVE: We sought to develop and validate a functional status instrument to assess asthma exacerbation severity in preschoolers. METHODS: The parent-completed Asthma Flare-up Diary for Young Children (ADYC), which was developed systematically, comprises 17 items, each scored from 1 (best) to 7 (worst). The ADYC was completed daily from the onset of an upper respiratory tract infection (URTI) until asthma symptom resolution; the cumulative daily score was reported...
March 2016: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/26338016/cross-cultural-translation-adaptation-and-reliability-of-the-malay-version-of-the-canadian-acute-respiratory-illness-and-flu-scale-carifs
#11
Anna Marie Nathan, Rafdzah Zaki, Rachael Rozario, Nurul Dhania, Siti Nur Sabrina Mohd Hamirudin, Kah Peng Eg, Sze Ying Kee, Cindy Teh, Kartini Abdul Jabar, Caroline Westerhout, Surendran Thavagnanam, Jessie de Bruyne
BACKGROUND: The Canadian Acute Respiratory Illness and Flu Scale (CARIFS) is a parent-proxy questionnaire that assesses severity of acute respiratory infections in children. The aim was to (a) perform a cross-cultural adaptation and (b) prove that the Malay CARIFS is a reliable tool. FINDINGS: The CARIFS underwent forward and backward translations as recommended by international guidelines. A pilot study was performed on the harmonised version and the final version of the Malay version of CARIFS was produced...
2015: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/26335189/a-homeopathic-combination-preparation-in-the-treatment-of-feverish-upper-respiratory-tract-infections-an-international-randomized-controlled-trial
#12
RANDOMIZED CONTROLLED TRIAL
Manuela Thinesse-Mallwitz, Vitaly Maydannik, Thomas Keller, Petra Klement
BACKGROUND: Upper respiratory tract infections (URTI) are very common and associated with considerable healthcare costs. We evaluated the clinical benefit of a homeopathic add-on therapy. PATIENTS AND METHODS: In this randomized controlled multinational clinical trial, patients (age range 1-65 years) with feverish URTI received either on-demand symptomatic standard treatment (ST group: paracetamol, ambroxol, and/or oxymetazoline), or homeopathic medication (IFC group: Influcid®) for 7 days plus the same on-demand standard treatment...
2015: Forschende Komplementärmedizin, Research in Complementary Medicine
https://www.readbyqxmd.com/read/26282368/injury-and-illness-surveillance-during-the-24th-men-s-handball-world-championship-2015-in-qatar
#13
Tone Bere, Juan-Manuel Alonso, Arnlaug Wangensteen, Arnhild Bakken, Cristiano Eirale, H Paul Dijkstra, Hosny Ahmed, Roald Bahr, Nebojsa Popovic
BACKGROUND: The IOC encourages international federations to establish systematic athlete injury and illness surveillance programmes. OBJECTIVE: To describe pattern of injuries and illnesses during the 24th Men's Handball World Championship 2015 by implementing the IOC injury and illness surveillance protocol. METHODS: The medical staff of participating teams (n=24) were requested to report all new injuries and illnesses during matches and/or training on a daily basis throughout the event (15 January to 1 February, 2015)...
September 2015: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/26266187/grave-complication-of-pharyngitis-lemierre-syndrome
#14
Suthar Pokhraj Prakashchandra, Ankit Kumar B Patel, Kimmyben Patel, Raj Kumar P Doshi, Narottam A Patel
Fusobacterium necrophorum is the causative agent in the pharyngitis. After invasion of the oropharyngeal mucosa by the organism leads to the development of the grave complications like superficial thrombophlebitis of internal jugular vein, septic emboli in the lung and coagulopathy. A 23-year-old male presented with chief complaints of sore throat, headache and high grade fever with past history of upper respiratory tract infection one month ago. On examination, he had high grade fever, tachycardia, hypotension and tender cervical lymph nodes...
June 2015: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/26249739/cochrane-commentary-probiotics-for-prevention-of-acute-upper-respiratory-infection
#15
COMMENT
Melissa Quick
BACKGROUND: Probiotics may improve a person's health by regulating their immune function. Some trials have shown that probiotic strains can prevent respiratory infections. Even though the previous version of our review showed benefits of probiotics for acute upper respiratory tract infections (URTIs), several new studies have been published. OBJECTIVES: To assess the effectiveness and safety of probiotics (any specified strain or dose), compared with placebo, in the prevention of acute URTIs in people of all ages, who are at risk of acute URTIs...
September 2015: Explore: the Journal of Science and Healing
https://www.readbyqxmd.com/read/26236610/fusobacterium-necrophorum-presenting-as-isolated-lung-nodules
#16
Rajiv Sonti, Christine Fleury
Fusobacterium necrophorum causes Lemierre's syndrome - a dramatic and distinct condition beginning with pharyngitis before proceeding to internal jugular vein septic thrombophlebitis and respiratory tract infection in otherwise healthy individuals. It is rare, but by far the most common pathway to parenchymal lung disease with this organism. Here we describe we a 34 year old healthy lady who was nontoxic without any antecedent illness who presented with lung nodules due to fusobacterium necrophorum as the sole manifestation of disease...
2015: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/26217421/concurrent-validity-between-a-shared-curriculum-the-internal-medicine-in-training-examination-and-the-american-board-of-internal-medicine-certifying-examination
#17
Stephen D Sisson, Amanda Bertram, Hsin-Chieh Yeh
BACKGROUND: A core objective of residency education is to facilitate learning, and programs need more curricula and assessment tools with demonstrated validity evidence. OBJECTIVE: We sought to demonstrate concurrent validity between performance on a widely shared, ambulatory curriculum (the Johns Hopkins Internal Medicine Curriculum), the Internal Medicine In-Training Examination (IM-ITE), and the American Board of Internal Medicine Certifying Examination (ABIM-CE)...
March 2015: Journal of Graduate Medical Education
https://www.readbyqxmd.com/read/26179648/adherence-to-guidelines-on-antibiotic-treatment-for-respiratory-tract-infections-in-various-categories-of-physicians-a-retrospective-cross-sectional-study-of-data-from-electronic-patient-records
#18
David Tell, Sven Engström, Sigvard Mölstad
OBJECTIVE: To study how prescription patterns concerning respiratory tract infections differ between interns, residents, younger general practitioners (GPs), older GPs and locums. DESIGN: Retrospective study of structured data from electronic patient records. SETTING: Data were obtained from 53 health centres and 3 out-of-hours units in Jönköping County, Sweden, through their common electronic medical record database. PARTICIPANTS: All physicians working in primary care during the 2-year study period (1 November 2010 to 31 October 2012)...
2015: BMJ Open
https://www.readbyqxmd.com/read/26176306/prevention-of-pneumococcal-infections-during-mass-gathering
#19
Jaffar A Al-Tawfiq, Ziad A Memish
The interest in mass gathering and its implications has been increasing due to globalization and international travel. The potential occurrence of infectious disease outbreaks during mass gathering is most feared. In this context, respiratory tract infections are of great concern due to crowding in a limited space which facilitates and magnifies the potential of disease spread among attendees. Pneumococcal disease is best described among pilgrims to Makkah and vaccination is one of the methods for the prevention of this disease...
2016: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/26168049/effective-apical-infection-of-differentiated-human-bronchial-epithelial-cells-and-induction-of-proinflammatory-chemokines-by-the-highly-pneumotropic-human-adenovirus-type-14p1
#20
Elena Lam, Mirja Ramke, Gregor Warnecke, Sonja Schrepfer, Verena Kopfnagel, Thomas Dobner, Albert Heim
BACKGROUND: Only a few pneumotropic types of the human adenoviruses (e.g. type B14p1) cause severe lower respiratory tract infections like pneumonia and acute respiratory distress syndrome (ARDS) even in immunocompetent patients. By contrast, many other human adenovirus (HAdV) types (e.g. HAdV-C5) are associated mainly with upper respiratory tract infections. This is in accordance with a highly physiological cell culture system consisting of differentiated primary human bronchial epithelial cells which are little susceptible for apical HAdV-C5 infections...
2015: PloS One
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