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Fresh bone allograft

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https://www.readbyqxmd.com/read/27863947/the-effects-of-low-dose-radiotherapy-on-fresh-osteochondral-allografts-an-experimental-study-in-rabbits
#1
Uğur Gönç, Mehmet Çetinkaya, Mesut Atabek
OBJECTIVE: The aim of this study was to investigate the effects of low-dose fractionated radiotherapy on cartilage degeneration after distal femoral fresh massive osteochondral allograft transplantation. METHODS: Twenty-four New Zealand White rabbits were divided into three groups of 8 rabbits each. All rabbits underwent distal femoral medial condyle fresh massive osteochondral allograft transplantation from California rabbits. The group 1 underwent transplantation without any preliminary process...
November 15, 2016: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/27859243/effect-of-infusion-of-mabs-to-tnfrsf25-on-graft-rejection-in-allo-immune-mice-receiving-autologous-marrow-transplantation
#2
Reginald M Gorczynski, Hassan Sadozai, Fang Zhu, Ismat Khatri
Significant barriers to transplantation exist for individuals who are pre-sensitized to donor Ag and have high titres of donor-reactive Ab. We report the effect of autologous BMTx after myeloablation in pre-sensitized mice along with the use of mAbs to TNFRSF25, expressed on Tregs. C57BL/6 mice, which had been sensitized earlier with BALB/c skin allografts, received secondary BALB/c grafts after the primary grafts had been rejected. Subsequently, recipient mice underwent myeloablation with cyclophosphamide and busulphan and were injected with T-cell depleted bone marrow from CD45...
November 17, 2016: Immunology
https://www.readbyqxmd.com/read/27800212/benefits-of-mineralized-bone-cortical-allograft-for-immediate-implant-placement-in-extraction-sites-an-in-vivo-study-in-dogs
#3
Valérie Orti, Philippe Bousquet, Paul Tramini, Cesar Gaitan, Brenda Mertens, Frédéric Cuisinier
PURPOSE: The aim of the present study was to evaluate the effectiveness of using a mineralized bone cortical allograft (MBCA), with or without a resorbable collagenous membrane derived from bovine pericardium, on alveolar bone remodeling after immediate implant placement in a dog model. METHODS: Six mongrel dogs were included. The test and control sites were randomly selected. Four biradicular premolars were extracted from the mandible. In control sites, implants without an allograft or membrane were placed immediately in the fresh extraction sockets...
October 2016: Journal of Periodontal & Implant Science
https://www.readbyqxmd.com/read/27771937/lumbar-intervertebral-disc-allograft-transplantation-healing-and-remodelling-of-the-bony-structure
#4
Y-C Huang, J Xiao, W Y Leung, W W Lu, Y Hu, K D Luk
Previous human study suggested that fresh-frozen intervertebral disc allograft transplantation can relieve neurological symptoms and restore segmental kinematics. Before wide clinical application, research into the pathophysiology of the postoperative disc allograft is needed. One important question that remains to be answered in disc allografting is the healing process of the host-graft interface and the subsequent change of the endplates. With the goat model for lumbar disc allografting, histology, micro-computed tomography analysis, scanning electron microscopy and energy-dispersive X-ray spectroscopy mapping were applied to evaluate the healing of the host-graft interfaces, the remodelling of subchondral bone, and the changes of the bony and cartilaginous endplates after transplantation...
October 19, 2016: European Cells & Materials
https://www.readbyqxmd.com/read/27766344/anterior-laxity-and-patient-reported-outcomes-7%C3%A2-years-after-acl-reconstruction-with-a-fresh-frozen-tibialis-allograft
#5
Emily Meike, S M Howell, M L Hull
PURPOSE: After reconstructing a torn ACL with a soft tissue allograft, the long-term healing process of graft maturation following the short-term healing process of graft incorporation into the bone tunnels might lead to recurring instability and concomitant decreases in the activity level, function, and patient satisfaction. Relying on roentgen stereophotogrammetric analysis (RSA), the primary purpose was to determine whether anterior laxity increased and whether patient-reported outcomes declined between 1 and 7 years for a particular graft construct, surgical technique, and rehabilitation programme...
October 20, 2016: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/27759878/the-dorsal-skinfold-chamber-a-versatile-tool-for-preclinical-research-in-tissue-engineering-and-regenerative-medicine
#6
Y-C Huang, J Xiao, W Y Leung, W W Lu, Y Hu, K D Luk
Previous human study suggested that fresh-frozen intervertebral disc allograft transplantation can relieve neurological symptoms and restore segmental kinematics. Before wide clinical application, research into the pathophysiology of the postoperative disc allograft is needed. One important question that remains to be answered in disc allografting is the healing process of the host-graft interface and the subsequent change of the endplates. With the goat model for lumbar disc allografting, histology, micro-computed tomography analysis, scanning electron microscopy and energy-dispersive X-ray spectroscopy mapping were applied to evaluate the healing of the host-graft interfaces, the remodelling of subchondral bone, and the changes of the bony and cartilaginous endplates after transplantation...
October 19, 2016: European Cells & Materials
https://www.readbyqxmd.com/read/27749380/iliac-crest-fresh-frozen-allografts-versus-autografts-in-oral-pre-prosthetic-bone-reconstructive-surgery-histologic-and-histomorphometric-study
#7
Claudia Dellavia, Michele Giammattei, Daniela Carmagnola, Federica Musto, Elena Canciani, Matteo Chiapasco
PURPOSE: The aim of this work was to compare histologically bone biopsies obtained during dental implant placement in atrophic jaws reconstructed with fresh-frozen bone (FFB) or autologous bone blocks. MATERIALS AND METHODS: Twenty partially or totally edentulous patients were treated either with iliac crest FFB grafts (14 patients; group A) or with iliac crest autografts (6 patients; group B). Seven to 9 months later, dental implants were placed in the reconstructed jaws and bone biopsies were harvested...
December 2016: Implant Dentistry
https://www.readbyqxmd.com/read/27735978/glenoid-reconstruction-with-distal-tibia-allograft-for-recurrent-anterior-shoulder-instability
#8
Rachel M Frank, Anthony A Romeo, Matthew T Provencher
Anterior glenoid bone loss is present in nearly all cases of recurrent anterior glenohumeral instability. Treating glenoid bone loss in the setting of recurrent instability is challenging, and often, soft tissue stabilization procedures in isolation are inadequate. The nonanatomic, incongruous joint resulting from most bony augmentation procedures has motivated investigators to find an alternative solution. Recently, the use of fresh distal tibia allograft has been reported as an anatomic, osteoarticular reconstructive option for restoring the glenoid arc and maintaining glenohumeral congruency...
October 13, 2016: Orthopedics
https://www.readbyqxmd.com/read/27717113/incorporation-and-remodeling-of-bone-block-allografts-in-the-maxillary-reconstruction-a-randomized-clinical-trial
#9
Daniel Deluiz, Luciano Santos Oliveira, Fábio Ramôa Pires, Teresita Reiner, Luciana Armada, Marcus A Nunes, Eduardo Muniz Barretto Tinoco
BACKGROUND: Severe alveolar atrophy often presents a challenge for the implant surgery. The significant lack of bone in the alveolar ridges may compromise the final restorations both from the aesthetic and functional standpoints. OBJECTIVES: To evaluate the behavior of bone block allografts for the maxillary augmentation and to investigate its incorporation, remodeling, and implant survival rates in two different healing time points. MATERIAL AND METHODS: Sixty-six consecutive patients (52 female/14 male, mean age: 57...
September 8, 2016: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/27631323/lyophilized-allogeneic-bone-tissue-as-an-antibiotic-carrier
#10
Débora C Coraça-Huber, Christoph G Ammann, Michael Nogler, Manfred Fille, Lars Frommelt, Klaus-Dieter Kühn, Christian Fölsch
The rising number of primary joint replacements worldwide causes an increase of revision surgery of endoprostheses due bacterial infection. Revision surgery using non-cemented implants seems beneficial for the long-term outcome and the use of antibiotic-impregnated bone grafts might control the infection and give a good support for the implant. In this study we evaluated the release of antibiotics from fresh-frozen and lyophilized allogeneic bone grafts. Lyophilized bone chips and fresh frozen bone chips were mixed with gentamicin sulphate, gentamicin palmitate, vancomycin, calcium carbonate/calcium sulphate impregnated with gentamicin sulphate, and calcium carbonate/calcium sulphate bone substitute material impregnated with vancomycin...
September 8, 2016: Cell and Tissue Banking
https://www.readbyqxmd.com/read/27570784/biomechanical-evaluation-of-posterior-cruciate-ligament-reconstruction-with-quadriceps-versus-achilles-tendon-bone-block-allograft
#11
Brian Forsythe, Marc S Haro, Ljiljana Bogunovic, Michael J Collins, Thomas A Arns, Katie J Trella, Elizabeth F Shewman, Nikhil N Verma, Bernard R Bach
BACKGROUND: Long-term studies of posterior cruciate ligament (PCL) reconstruction suggest that normal stability is not restored in the majority of patients. The Achilles tendon allograft is frequently utilized, although recently, the quadriceps tendon has been introduced as an alternative option due to its size and high patellar bone density. PURPOSE/HYPOTHESIS: The purpose of this study was to compare the biomechanical strength of PCL reconstructions using a quadriceps versus an Achilles allograft...
August 2016: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/27512226/decalcified-allograft-in-repair-of-lytic-lesions-of-bone-a-study-to-evolve-bone-bank-in-developing-countries
#12
Anil Kumar Gupta, Kumar Keshav, Praganesh Kumar
BACKGROUND: The quest for ideal bone graft substitutes still haunts orthopedic researchers. The impetus for this search of newer bone substitutes is provided by mismatch between the demand and supply of autogenous bone grafts. Bone banking facilities such as deep frozen and freeze-dried allografts are not so widely available in most of the developing countries. To overcome the problem, we have used partially decalcified, ethanol preserved, and domestic refrigerator stored allografts which are economical and needs simple technology for procurement, preparation, and preservation...
July 2016: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/27499323/painful-pediatric-sacral-aneurysmal-bone-cyst-treated-by-curettage-and-fresh-frozen-allograft
#13
Murat Aydın, Güray Toğral, Fevzi Kekeç, Murat Arıkan, Şafak Güngör
In this article, we report a rarely localized sacral aneurysmal bone cyst (ABC) successfully treated by curettage and bone grafting with fresh frozen fibular allograft (FFA) in a 14-year-old girl patient. The cyst was at S1-2 level and treated with aggressive curettage and bone grafting with two FFAs. All complaints of the patient resolved at the 24th month of treatment and bony union of the cystic cavity was observed radiologically. Curettage and FFA may be safely used for filling the cavity in the treatment of sacral ABC in pediatric age to provide a structural and biological reinforcement...
August 2016: Eklem Hastalıkları Ve Cerrahisi, Joint Diseases & related Surgery
https://www.readbyqxmd.com/read/27496906/osteochondral-allograft-transplantation-in-patients-with-osteochondritis-dissecans-of-the-knee
#14
Kamran N Sadr, Pamela A Pulido, Julie C McCauley, William D Bugbee
BACKGROUND: Osteochondritis dissecans (OCD) of the knee can be difficult to treat. Cartilage restoration techniques are often indicated when the lesion or fragment cannot be salvaged and the patient remains symptomatic. Fresh osteochondral allograft (OCA) transplantation can restore both bone and cartilage defects characteristic of OCD. HYPOTHESIS: We hypothesized that osteochondral allografting is a successful method for treating OCD of the knee. STUDY DESIGN: Case series; Level of evidence, 4...
August 5, 2016: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/27370651/subtalar-distraction-arthrodesis-with-fresh-frozen-femoral-neck-allograft-a-retrospective-case-series
#15
Spencer J Monaco, Roberto A Brandao, Jeffrey M Manway, Patrick R Burns
UNLABELLED: Subtalar joint distraction arthrodesis has been well reported with use of structural iliac crest or local autologous bone graft for malunited calcaneal fractures. Early reports for structural allograft did not yield good, consistent results, leading to a subsequent lack of recommendation in previous literature. Newer studies have had promising results utilizing femoral allograft as an alternative to autogenous bone graft. We performed a retrospective chart review on 10 patients (12 feet) undergoing subtalar joint distraction arthrodesis with femoral neck allograft for malunited calcaneal fractures...
October 2016: Foot & Ankle Specialist
https://www.readbyqxmd.com/read/27367419/fresh-frozen-bone-allografts-in-maxillary-alveolar-augmentation-analysis-of-the-complications-adverse-outcomes-and-implant-survival
#16
Daniel Deluiz, Luciano Oliveira, Paul Fletcher, Fábio R Pires, Marcus A Nunes, Eduardo M B Tinoco
BACKGROUND: The success of any bone augmentation procedure is dependent on several factors. As complications occur in some cases, the aims of the this study are to analyze the adverse events associated with the placement of fresh-frozen allografts during alveolar ridge augmentation and to assess the one year survival of dental implants placed in the reconstructed sites. METHODS: Fifty-eight consecutive patients (43 females and 15 Males) aged 38 to 76 years (mean: 58 ± 9...
July 1, 2016: Journal of Periodontology
https://www.readbyqxmd.com/read/27358284/fresh-osteochondral-allograft-versus-autograft-twelve-month-results-in-isolated-canine-knee-defects
#17
Eric C McCarty, Ryan R Fader, Justin J Mitchell, R Edward Glenn, Hollis G Potter, Kurt P Spindler
BACKGROUND: Osteochondral autografts and allografts have been widely used in the treatment of isolated grade 4 articular cartilage lesions of the knee. However, there is a paucity of literature regarding the basic science investigating the direct comparison between fresh osteochondral allografts to autografts. HYPOTHESIS: At 12 months, fresh osteochondral allografts are equal to autografts with respect to function, bony incorporation into host bone, and chondrocyte viability...
September 2016: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/27357530/bone-albumin-filling-decreases-donor-site-morbidity-and-enhances-bone-formation-after-anterior-cruciate-ligament-reconstruction-with-bone-patellar-tendon-bone-autografts
#18
Károly Schandl, Dénes B Horváthy, Attila Doros, Ernő Majzik, Charlotte M Schwarz, Lajos Csönge, Géza Abkarovits, László Bucsi, Zsombor Lacza
PURPOSE: Donor site pain affects 32-43 % of patients after anterior cruciate ligament surgery when the autograft is freshly harvested bone-patellar tendon-bone tissue. Our aim was to compare functional and morphological differences between donor sites with and without serum albumin-coated bone allograft filling. METHODS: After harvesting and implanting the graft, the tibia site was filled with either fresh autologous cancellous bone enhanced with albumin-coated allograft or autologous bone alone...
June 29, 2016: International Orthopaedics
https://www.readbyqxmd.com/read/27338957/posterior-shoulder-dislocation-with-a-reverse-hill-sachs-lesion-treated-with-frozen-femoral-head-bone-allograft-combined-with-osteochondral-autograft-transfer
#19
Dimitrios S Mastrokalos, Georgios N Panagopoulos, Ioannis P Galanopoulos, Panayiotis J Papagelopoulos
: Management of a posterior shoulder dislocation with an associated reverse Hill-Sachs lesion is challenging, both diagnostically and therapeutically. Diagnosis is frequently delayed or missed, whereas the resulting humeral head defect is often larger and more difficult to salvage than in anterior shoulder dislocations. This report presents the case of a 29-year-old male with a recurrent posterior shoulder dislocation associated with a large reverse Hill-Sachs defect, treated with bone augmentation of the lesion with a combination of fresh femoral head allograft and a locally harvested humeral head autograft transfer, with a successful outcome...
June 23, 2016: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/27180922/a-biomechanical-analysis-of-different-clavicular-tunnel-diameters-in-anatomic-acromioclavicular-ligament-reconstruction
#20
Andreas Voss, Knut Beitzel, Farhang Alaee, Alex Dukas, Elmar Herbst, Elifho Obopilwe, John Apostolakos, Jessica DiVenere, Hardeep Singh, Mark P Cote, Augustus D Mazzocca
PURPOSE: To evaluate the biomechanical stability of a tendon-to-clavicle bone interface fixation of a graft in revision acromioclavicular reconstruction. METHODS: Fifteen fresh-frozen cadaveric shoulders were used. All specimens underwent bone density evaluation. For the primary reconstruction, a 5-mm semitendinosus allograft was inserted into a 5-mm bone tunnel at 25 and 45 mm from the lateral end of the clavicle using a 5.5 × 8-mm PEEK (polyether ether ketone) tenodesis screw...
August 2016: Arthroscopy: the Journal of Arthroscopic & related Surgery
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