keyword
MENU ▼
Read by QxMD icon Read
search

Total laryngectomy

keyword
https://www.readbyqxmd.com/read/29778552/alterations-in-oxidative-stress-markers-in-laryngeal-carcinoma-patients
#1
Nazim Bozan, Halit Demir, Tülay Gürsoy, Hüseyin Özkan, Ufuk Düzenli, Eren Sarıkaya, Mahfuz Turan, Ahmet Faruk Kiroglu, Hakan Çankaya
BACKGROUND: Data describing how laryngeal cancer affects oxidative stress markers and antioxidants are limited. This study investigated serum antioxidant enzyme activities and oxidative stress markers before and after laryngectomies in patients with laryngeal cancer. METHODS: A total of 29 patients with laryngeal cancer and 25 healthy control subjects were enrolled. Serum malondialdehyde (MDA) levels and superoxide dismutase (SOD), glutathione peroxidase (GSHPx), catalase (CAT), paraoxonase (PON), and arylesterase activities were measured spectrophotometrically...
May 16, 2018: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/29777295/laser-debulking-or-tracheotomy-in-airway-management-prior-to-total-laryngectomy-for-t4a-laryngeal-cancer
#2
Djamil Semdaie, Fabienne Haroun, Odile Casiraghi, François Bidault, Stéphane Temam, François Janot, Philippe Gorphe
PURPOSE: Retrospective studies have shown that tracheotomy prior to total laryngectomy (TL) is associated with decreased survival. We sought to investigate whether this is due to higher local invasiveness associated with obstructive disease or whether it is the result of tracheotomy itself. METHODS: We reviewed patients with a T4a (AJCC 7th edition) laryngeal squamous-cell carcinoma treated with a primary TL followed by adjuvant radiotherapy between 2001 and 2013...
May 18, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29764015/-treatment-and-prognosis-of-264-patients-with-hypopharyngeal-carcinoma
#3
W Xu, Z H Lyu, N Sa, J K Ma, J J Tian, S H Feng, P Cui, H Y Cao
Objective: To investigate the key factors influencing the prognosis of hypopharyngeal carcinoma and the therapeutic methods improving the efficacy of treatments for hypopharyngeal carcinoma. Methods: Two hundred and sixty-four cases of hypopharyngeal squamous cell carcinoma treated from May 2010 to May 2015 were analyzed retrospectively. There were 211 cases of pyriform sinus carcinoma, 37 cases of posterior pharyngeal wall carcinoma, and 16 cases of postcricoid carcinoma. According to UICC 2002 criteria, 2 cases were for stage Ⅰ, 14 for stage Ⅱ, 32 for stage Ⅲ and 216 for stage Ⅳ...
May 7, 2018: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/29756613/neutrophil-to-lymphocyte-ratio-as-a-prognostic-factor-for-pharyngocutaneous-fistula-after-total-laryngectomy
#4
F T Aires, R A Dedivitis, M A V Kulcsar, D M Ramos, C R Cernea
The role of systemic inflammatory response as a prognostic factor has been proposed in a variety of cancers. The purpose of this study was to investigate the prognostic value of the pretreatment neutrophil-to-lymphocyte ratio (NLR) in the incidence of pharyngocutaneous fistula (PCF) in patients who underwent total laryngectomy. We conducted a retrospective cohort analysis of 141 patients with squamous cell carcinoma of larynx who underwent total laryngectomy from 2009 to 2015. The incidence of PCF was 49.6%...
February 2018: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/29756480/tracheoesophageal-prosthesis-use-is-associated-with-improved-overall-quality-of-life-in-veterans-with-laryngeal-cancer
#5
Ramya S Patel, Tiffany Mohr, Christine Hartman, Carol Stach, Andrew G Sikora, Jose P Zevallos, Vlad C Sandulache
OBJECTIVES: Veterans have an increased risk of laryngeal cancer, yet their oncologic and functional outcomes remain understudied. We sought to determine the longitudinal impact of tracheoesophageal puncture and voice prosthesis on quality-of-life measures in veterans following total laryngectomy (TL). METHODS: We performed a cross-sectional analysis of TL patients (n = 68) treated at the Michael E. DeBakey Veterans Affairs Medical Center using the Voice Handicap Index (VHI), MD Anderson Dysphagia Index (MDADI), and University of Washington Quality of Life Index (UW-QOL)...
May 1, 2018: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/29756307/age-adjusted-comorbidity-and-survival-in-locally-advanced-laryngeal-cancer
#6
Collin F Mulcahy, Abdallah S R Mohamed, Aasheesh Kanwar, Katherine A Hutcheson, Alokananda Ghosh, David Vock, Randal S Weber, Stephen Y Lai, Gary Brandon Gunn, Mark Zafereo, William H Morrison, Renata Ferrarotto, Adam S Garden, David I Rosenthal, Clifton D Fuller
BACKGROUND: The purpose of this study was to quantify the relationship among age, pretreatment comorbidity, and survival outcomes in patients with locally advanced laryngeal cancer. METHODS: Baseline comorbidity data were collected and age-adjusted Charlson Comorbidity Index (CCI) was calculated for each case. Kaplan-Meier and Cox proportional hazards modeling were used to determine associations with survival. RESULTS: For 548 patients, with a median age of 59 years (range 31-91 years), 58% were treated with larynx preservation and the rest with total laryngectomy and adjuvant radiotherapy (RT)...
May 13, 2018: Head & Neck
https://www.readbyqxmd.com/read/29756264/study-design-and-early-result-of-a-phase-i-study-of-sabr-for-early-stage-glottic-cancer
#7
Tosol Yu, Chan Woo Wee, Noorie Choi, Hong-Gyun Wu, Hyun-Cheol Kang, Jong Min Park, Jung-In Kim, Jin Ho Kim, Tack-Kyun Kwon, Eun-Jae Chung
OBJECTIVE: Avoidance of organs at risk has become possible with advances in image-guided volumetric-modulated arc therapy (VMAT) techniques. This study was designed to evaluate the safety and feasibility of stereotactic ablative radiotherapy (SABR) for early stage glottic cancer. This report presents the preliminary result of the first and second dose level. METHODS: Fraction size was increased from 3.5 gray (Gy) (total dose 59.5 Gy) to 9 Gy (total dose 45 Gy). Dose-limiting toxicities were defined as grade 3 or higher treatment-related toxicities...
May 14, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29725412/locally-advanced-laryngeal-cancer-total-laryngectomy-or-primary-non-surgical-treatment
#8
Aleš Čoček, Miloslav Ambruš, Alena Dohnalová, Martin Chovanec, Martina Kubecová, Kateřina Licková
Between January 1997 and December 2013, the Charles University 3rd Medical School and Royal Vinohrady Teaching Hospital Ear, Nose and Throat oncology team treated 185 patients with advanced laryngeal cancer, which, from a surgical perspective, required a total laryngectomy. Overall, ~70% of these patients (n=129) underwent conventional treatment (i.e., total laryngectomy with post-operative radiotherapy), and ~30% (n=56) were treated with larynx preservation protocols (including primary radiotherapy, neoadjuvant chemotherapy followed by radiotherapy or chemoradiotherapy, or primary chemoradiotherapy)...
May 2018: Oncology Letters
https://www.readbyqxmd.com/read/29721544/defining-the-low-risk-salvage-laryngectomy-a-single-center-retrospective-analysis-of-pharyngocutaneous-fistula
#9
Sarju S Vasani, Daniel Youssef, Charles Lin, Annabelle Wellham, Robert Hodge
Objectives: Salvage total laryngectomies (STL) are not a homogeneous group. Most will fall into two groups: i) Patients with previous AJCC stage I/II larynx cancer who have had radiotherapy to the larynx only (STL-LOR), or ii) Patients who have had previous AJCC stage III/IV larynx cancer and subsequent radiotherapy to the larynx and draining nodal basins with concurrent cisplatin chemotherapy (STL-CRT). We aimed to compare PCF rates following STL in these two groups. Methods: A retrospective review of the department's cohort between January 2010 and August 2015 was conducted...
April 2018: Laryngoscope Investigative Otolaryngology
https://www.readbyqxmd.com/read/29713885/supracricoid-partial-laryngectomy-for-radiorecurrent-laryngeal-cancer-a-systematic-review-of-the-literature-and-meta-analysis
#10
REVIEW
Armando De Virgilio, Raul Pellini, Giuseppe Mercante, Giovanni Cristalli, Valentina Manciocco, Diana Giannarelli, Giuseppe Spriano
PURPOSE: The objective of the current systematic review with meta-analysis was to report the pooled survival outcomes of supracricoid partial laryngectomy in the setting of radiorecurrent laryngeal cancer to investigate if and when an organ-sparing surgical treatment is adequate. METHODS: The search included all original papers from 1990 to December 2017. The search terms included the following: cricohyoepiglottopexy; cricohyoidopexy; cricohyopexy; horizontal laryngectomy; and partial, subtotal, supracricoid, and supraglottic laryngectomy...
April 30, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29707499/cervical-exenteration
#11
REVIEW
Uma M Sachdeva, Michael Lanuti
Cervical exenteration is a radical procedure for the treatment of locally invasive cancers of the trachea, esophagus, or thyroid, as well as recurrent tumors at the site of a tracheal stoma, and occasionally for benign disease. Exenteration involves removal of the larynx, pharynx, esophagus, and trachea, as well as associated lymphatic tissue. The tracheal stump is brought up as a cervical or mediastinal tracheostomy, depending on the length and the location of the distal resection site. The alimentary tract can be reconstructed with several types of conduits, but most commonly the stomach or left colon are used...
March 2018: Annals of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/29699878/the-role-of-red-cell-distribution-width-in-the-locoregional-recurrence-of-laryngeal-cancer
#12
Gülpembe Bozkurt, Arzu Yasemin Korkut, Pınar Soytaş, Senem Kurt Dizdar, Zeynep Nur Erol
INTRODUCTION: Although the red cell distribution width has been reported as a reliable predictor of prognosis in several types of cancer, to our knowledge few reports have focused on the prognostic value of red cell distribution width in laryngeal carcinoma. OBJECTIVE: We aimed to explore whether the pretreatment red cell distribution width predicted recurrence in laryngeal cancer patients is a simple, reproducible, and inexpensive prognostic biomarker. METHODS: All laryngeal cancer patients who underwent curative surgery (n=132) over a 7 year study period were evaluated...
April 13, 2018: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/29671922/support-following-total-laryngectomy-exploring-the-concept-from-different-perspectives
#13
J M Bickford, J Coveney, J Baker, D Hersh
Adjustment after total laryngectomy is complex, and the resultant support needs are extensive. Current practice is often guided by health-related quality of life measures. While useful, many of these tools were developed without considering the perspectives of people who have experienced the surgery. To improve understanding of the support needs after total laryngectomy, multiple viewpoints were examined, for example individuals with a laryngectomy (IWL), significant others (SO) and health professionals (HP)...
April 19, 2018: European Journal of Cancer Care
https://www.readbyqxmd.com/read/29659184/the-human-laryngeal-innervation-revisited-the-role-of-the-neural-connections
#14
C Martín-Oviedo, E Maranillo, J R Sañudo, P Pérez-LLoret, E Verdú, T Martínez-Guirado, O Álvarez-Montero, J M Gómez Martín-Zarco, T Vázquez
In spite that vascular inconvenients or immunological rejections have been solved in relation with larynx transplant, a successful functional reinnervation has not been achieved. Some studies have suggested that laryngeal nerve connection may contain motor fibers, which could explain unexpected evoked responses in electromyographic studies or the different positions adopted of the vocal folds after similar nerve lesions. Ten patients with unexpected evoked responses after laryngeal nerve stimulation were selected...
April 16, 2018: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/29650373/repair-of-post-laryngectomy-pharyngocutaneous-fistulas-using-a-pectoralis-major-flap
#15
Anna Sumarroca, Elena Rodríguez-Bauzà, Joan Lop-Gros, Jacinto García, Montserrat López, Miquel Quer, Xavier León
INTRODUCTION: The pectoralis major flap is a reconstructive option to consider in the treatment of pharyngocutaneous fistula after a total laryngectomy. There are not large studies assessing variables related to pharyngocutaneous fistula recurrence after removal of the larynx. Our objectives were to review the results obtained with this type of treatment when pharyngocutaneous fistula appears in laryngectomized patients, and to evaluate variables related to the results. METHODS: We retrospectively reviewed our results using either a myocutaneous or fasciomuscular pectoralis major flap to repair pharyngocutaneous fistula in 50 patients...
April 5, 2018: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/29614529/-speech-intelligibility-and-marital-quality-in-couples-after-total-laryngectomy-partners-view
#16
Isabelle Steckel, Susanne Singer, Judith Keszte, Friedemann Pabst, Alexandra Meyer
BACKGROUND: Following the total removal of the larynx (TL) as a result of laryngeal cancer, both, patients and partners face significant challenges caused by altered speech intelligibility. We analysed effects of the altered speech intelligibility on dyadic communication and marital quality from the partners' point of view. METHODS: 70 partners of cancer patients with laryngectomy from 13 hospitals in Central Germany were interviewed 2 (t1) and 3 (t2) years after laryngectomy...
April 3, 2018: Psychotherapie, Psychosomatik, Medizinische Psychologie
https://www.readbyqxmd.com/read/29601122/oncologic-outcomes-of-surgical-treatment-for-t3-glottic-laryngeal-squamous-cell-carcinoma
#17
Jian Zhou, Liang Zhou, Lei Tao, Ming Zhang, Haitao Wu, Xiaoling Chen, Xiaoming Li, Cai Li, Hongli Gong
BACKGROUND: The purpose of this study was to assess the clinical results of patients with T3 glottic laryngeal carcinoma treated with total laryngectomy or partial laryngectomy. METHODS: We conducted a retrospectively review of 307 patients with T3 glottic laryngeal squamous cell carcinoma (SCC). RESULTS: The 5-year cancer-specific survival (CSS) rate was 71.5% and the overall survival (OS) rate was 70.6%. For patients who underwent total laryngectomy, the 5-year disease-free survival (DFS) rate was 59...
March 30, 2018: Head & Neck
https://www.readbyqxmd.com/read/29590652/a-novel-device-for-placement-of-a-secondary-tracheoesophageal-voice-prosthesis-a-preliminary-feasibility-study
#18
Andrew T Tkaczuk, Rodney J Taylor, Jeffrey S Wolf
BACKGROUND: Tracheoesophageal puncture (TEP) for post-laryngectomy speech rehabilitation can be performed at the time of laryngectomy (primary) or at a subsequent time (secondary). Traditionally, the secondary procedure is performed using a rigid esophagoscope. Diseases like esophageal stricture, limited neck extension, and soft-tissue fibrosis can make this procedure technically challenging or impossible. We developed a novel device to perform a secondary tracheoesophageal puncture using a flexible esophagoscope...
March 28, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/29580843/in-clinic-secondary-tracheoesophageal-puncture-and-voice-prosthesis-placement-in-laryngectomees
#19
E Ricci, G Riva, F Dagna, E Seglie, A L Cavalot
Secondary tracheoesophageal puncture (TEP) with voice prosthesis placement represents one of the possibility to restore vocal function after total laryngectomy. However, some patients have comorbidities that contraindicate general anesthesia. In our department, an in-clinic TEP procedure for retrograde voice prosthesis placement was developed. It allows the immediate placement of the prosthesis and the avoidance of the use of dilators. We described our technique with advantages and pitfalls. The Provox Vega Puncture Set was used...
March 23, 2018: European Annals of Otorhinolaryngology, Head and Neck Diseases
https://www.readbyqxmd.com/read/29574599/pharyngeal-fistulas-after-total-laryngectomy-with-and-without-tracheostoma-plasty-according-to-herrmann
#20
Philipp Wolber, David Schwarz, Matthias Balk, Nicola Luckscheiter, Claudia Sommer, Antoniu-Oreste Gostian
PURPOSE: Pharyngeal fistula (PF) is one of the most common complications after total laryngectomy (TL). The tracheostoma plasty technique according to Herrmann (TPH) represents an alternative surgical technique to shape the tracheostoma. The aim of this study was to determine whether the performance of a TPH affects the incidence of PF after TL. A secondary aim was to identify potential risk factors for the development of PF with regard to TPH. METHODS: Retrospective evaluation of records of 151 consecutive patients at two tertiary care centers with regard to the occurrence and risk factors of PF after TL with and without TPH...
May 2018: European Archives of Oto-rhino-laryngology
keyword
keyword
59048
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"