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Total laryngectomy

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https://www.readbyqxmd.com/read/27893554/stapler-esophageal-closure-during-total-laryngectomy
#1
Onur Ismi, Murat Unal, Yusuf Vayisoglu, Mesut Yesilova, Ilter Helvaci, Kemal Gorur, Cengiz Ozcan
Mechanical esophageal closure with stapler during total laryngectomy has been used by various authors to decrease the surgical time and pharyngocutaneous fistula (PCF) rates. In a few of the studies, surgical site infection (SSI) rates are mentioned and none of the studies emphasize the effect of decreased surgical time on postoperative cardiovascular and cerebrovascular complications. In this study, the authors compared the PCF rates, SSI rates, operation times between 30 mechanical stapler and 40 manual esophageal closure during total laryngectomy for laryngeal cancer patients...
November 23, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27888508/outcomes-following-laryngectomy-refusal-after-insufficient-response-to-induction-chemotherapy
#2
Philippe Gorphe, Margarida Matias, Pierre Blanchard, Caroline Even, Charles Ferte, Yungan Tao, Stéphane Temam, François Bidault, François Janot
OBJECTIVE: To review patients who refused a total laryngectomy and were treated with radiotherapy (RT) after insufficient response to induction chemotherapy in a larynx preservation protocol for advanced-stage cancer of the larynx and to compare their outcomes with good responders. STUDY DESIGN: Retrospective cohort study. METHODS: Eighty-six patients treated with induction chemotherapy followed by RT were included in the analysis: 75 good responders and 11 insufficient responders who refused surgery...
November 26, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27882709/technical-note-using-a-tracheal-stent-for-conservative-management-of-speaking-valve-associated-tracheo-oesophageal-fistula
#3
M Cunnane, S Patil, R Sothinathan, D Walker, M Gaulton, L Pitkin
Surgical voice rehabilitation is an essential dimension of treatment following total laryngectomy. The gold standard is tracheo-oesophageal puncture and speaking valve placement. Whilst offering excellent phonation in many patients, there is a well-documented risk of valve associated fistula formation, the incidence of which varies from 1 to 21% (1) . Risk factors for delayed valve associated tracheo-oesophageal fistula include post chemo-radiotherapy (salvage laryngectomy), oesophageal stricture, persistent fungal infection and poor patient compliance in managing their speaking valve(2) ...
November 24, 2016: Clinical Otolaryngology
https://www.readbyqxmd.com/read/27879602/health-related-quality-of-life-following-reconstruction-for-common-head-and-neck-surgical-defects
#4
Wess A Cohen, Claudia R Albornoz, Peter G Cordeiro, Jennifer Cracchiolo, Elizabeth Encarnacion, Meghan Lee, Michele Cavalli, Snehal Patel, Andrea L Pusic, Evan Matros
BACKGROUND: Improved understanding and management of health-related quality of life represents one of the greatest unmet needs for patients with head and neck malignancies. The purpose of this study was to prospectively measure health-related quality of life associated with different anatomical (head and neck) surgical resections. METHODS: A prospective analysis of health-related quality of life was performed in patients undergoing surgical resection with flap reconstruction for stage II or III head and neck malignancies...
December 2016: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/27846104/validation-of-the-chinese-version-of-the-readiness-for-hospital-discharge-scale-on-patients-who-have-undergone-laryngectomy
#5
Huiling Zhao, Xianqiong Feng, Rong Yu, Deying Gu, Xiaoqin Ji
BACKGROUND: The Readiness for Hospital Discharge Scale (RHDS) was designed to assess the readiness of patients for discharge. The original English-language instrument has shown high degrees of reliability and validity, but no Chinese version of the scale has been verified. PURPOSE: The purpose of this study was to translate the RHDS into Chinese and assess the psychometric properties of this scale on laryngectomy patients in China. METHODS: The RHDS was translated into Chinese using forward and back translation, semantic equivalence assessment, and pilot testing...
December 2016: Journal of Nursing Research: JNR
https://www.readbyqxmd.com/read/27833963/anterior-commissure-laryngeal-neoplasm-endoscopic-management
#6
Nicolae Constantin Balica, Mărioara Poenaru, Eugen HoraŢiu Ştefănescu, Eugen Radu Boia, Caius Ion Doroş, Flavia Baderca, Octavian Mazilu
The CO2 laser surgery represents a treatment method of laryngeal bicordal and anterior commissure glottic cancer T1b, T2, N0. In Department of ENT, Timisoara, Romania, during 1.01.2001-31.12.2011 were analyzed 781 files from patients with laryngeal neoplasm. One hundred twenty-seven patients presented the tumor that involved both vocal cords and anterior commissure, stages T1b, T2 and T3. Therapeutic options included CO2 laser microsurgical excision for 55 (43.30%) patients, frontolateral hemilaryngectomy for 16 (12...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/27833247/malignant-tumors-of-the-larynx-clinicopathologic-profile-and-implication-for-late-disease-presentation
#7
Ayotunde James Fasunla, Oluwole Agboola Ogundoyin, Paul Adekunle Onakoya, Onyekwere George Nwaorgu
BACKGROUND: Malignant laryngeal tumors are uncommon. Late presentation of the disease may worsen management outcomes. We described the epidemiologic, clinicopathologic profile, and management outcomes of laryngeal tumors in a tertiary health institution in Nigeria. MATERIALS AND METHODS: An 11-year retrospective review of medical records of patients managed for malignant laryngeal tumor at the University College Hospital, Ibadan, Nigeria, was performed. RESULTS: There were 97 patients comprising 74 (76...
September 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27831517/nasal-and-tracheal-cytological-changes-after-total-laryngectomy-in-long-term-survivors
#8
Giuseppe Riva, Monica Boita, Andrea Corvino, Matteo Sensini, Daniela Peruzzetto, Luigi Chiusa, Giancarlo Pecorari, Massimiliano Garzaro
OBJECTIVE: Complete separation of upper and lower respiratory tract after total laryngectomy results in permanent effects on nasal cavities and tracheo-bronchial airways. Aim of this study is evaluating nasal and tracheal cytological alterations of mucosa in laryngectomy long-term survivors, analyzing the feasibility of scraping for cytological examination of tracheal mucosa. METHODS: Twenty-five laryngectomy patients underwent symptoms' evaluation, endoscopic fiber optic examination, prick tests, and nasal and tracheal scraping for cytological exam...
November 9, 2016: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/27799228/synchronous-perforations-of-the-oesophagus-and-stomach-by-air-insufflation-an-uncommon-complication-of-endoscopic-dilation
#9
Arthur M Fung, Fion S Chan, Ian Y Wong, Simon Law
A 72-year-old woman had a history of carcinoma of the hypopharynx treated by total laryngectomy, circumferential pharyngectomy and free jejunal graft. Endoscopic dilation of the pharyngojejunal anastomotic stricture resulted in synchronous perforations of the oesophagus and stomach. We postulate that the perforations were caused by high intraoesophageal and intragastric pressure resulted from air insufflation during the procedure; in a situation simulating closed-loop obstruction, because of proximal obstruction by the endoscope at the stricture site and distal obstruction by pylorospasm...
October 31, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27798871/radiotherapy-associated-furin-expression-and-tumor-invasiveness-in-recurrent-laryngeal-cancer
#10
Myungjin Lee, Chang Hwan Ryu, Hyo Won Chang, Gui Chul Kim, Seong Who Kim, Sang Yoon Kim
BACKGROUND/AIM: Recurrent laryngeal cancer often shows an aggressive phenotype after radiotherapy and does not respond to conventional therapeutic strategies. In this study, we investigated the contribution of furin to cellular invasiveness in radio-resistant laryngeal cancer. MATERIALS AND METHODS: Using previously established AMC-HN-3 and AMC-HN-8 cell lines from laryngeal carcinoma patients, recurrent laryngeal cancer models were generated by cumulative irradiation (AMC-HN-3-70Gy and AMC-HN-8-70Gy)...
October 2016: Anticancer Research
https://www.readbyqxmd.com/read/27793000/dirc3-and-near-nabp1-genetic-polymorphisms-are-associated-laryngeal-squamous-cell-carcinoma-patient-survival
#11
Zhen Shen, Wanli Ren, Yanxia Bai, Zhengshuai Chen, Jingjie Li, Bin Li, Tianbo Jin, Peilong Cao, Yuan Shao
Laryngeal squamous cell carcinoma (LSCC) is one of the most common and aggressive malignancies of the upper digestive tract. The present study is a retrospective analysis of data from a prospective longitudinal study. A total of 170 male LSCC patients (average age, 60.75±10.082) at the First Affiliated Hospital of Xi'an Jiaotong University School of Medicine were recruited between January 2002 and April 2013 for this study. We assessed correlations between patient characteristics and survival, and sequenced genomic DNA from patient peripheral blood samples...
October 25, 2016: Oncotarget
https://www.readbyqxmd.com/read/27789194/carotid-blowout-syndrome-in-patients-treated-by-larynx-cancer
#12
Carlos Miguel Chiesa Estomba, Frank Alberto Betances Reinoso, Alejandra Osorio Velasquez, Olalla Castro Macia, Maria Jesus Gonzalez Cortés, Jesus Araujo Nores
INTRODUCTION: Carotid blowout syndrome is an uncommon complication for patient treated by head and neck tumours, related with a high mortality rate. OBJECTIVE: The aim of this study was to study the risk of carotid blowout in a large cohort of patients treated only by larynx cancer. METHODS: Retrospective analysis of patients older than 18 years, treated by larynx cancer who developed a carotid blowout syndrome in a tertiary academic centre...
September 29, 2016: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/27778345/evaluating-organ-preservation-outcome-as-treatment-endpoint-for-t1an0-glottic-cancer
#13
Tsu-Hui Hubert Low, David Yeh, Tina Zhang, Rakhna Araslanova, J Alex Hammond, David Palma, Nancy Read, Varagur Venkatesan, S Danielle MacNeil, John Yoo, Anthony Nichols, Kevin Fung
OBJECTIVES/HYPOTHESIS: Common endpoints in reporting the outcomes for early glottic cancer do not highlight the importance of organ preservation. We evaluated the treatment outcomes among patients with T1aN0 laryngeal cancer with laryngectomy-free disease-specific survival (LFS-DSS), which is defined as time to total laryngectomy or time to death from cancer cause, against all other endpoints. STUDY DESIGN: Outcome research on an institutional database. METHODS: A retrospective review covered all consecutive patients from 2003 to 2013...
October 25, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27769535/chondrosarcoma-of-the-hyoid-bone-report-of-a-case-and-a-literature-review-of-the-suitable-treatment-strategy
#14
Daisuke Maki, Taisuke Mori, Masanori Teshima, Kenya Kobayashi, Fumihiko Matsumoto, Akihiro Sakai, Kenji Okami, Seiichi Yoshimoto
Chondrosarcoma is a rare malignant tumor occurring in the trunk and long bones. We present an extremely rare case of chondrosarcoma of the hyoid bone with clinical and pathological correlation and a literature review. We searched all cases of the hyoid chondrosarcoma in PubMed (MEDLINE) between 1990 and 2015. Eighteen cases were analyzed, including the present case. Most of them were low grade type. In 12 cases where intraoperative findings were recorded, no adhesion to the surrounding tissue was observed. Chondrosarcoma of the hyoid bone is usually low grade type, and there may be no invasion to the adjacent structures even if invasion is suspected by imaging findings...
October 18, 2016: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/27752264/critical-care-admissions-following-total-laryngectomy-is-it-time-to-change-our-practice
#15
Hussein Walijee, Alexandria Morgan, Bethan Gibson, Sandeep Berry, Ali Jaffery
Critical Care Unit (CCU) beds are a limited resource and in increasing demand. Studies have shown that complex head and neck patients can be safely managed on a ward setting given the appropriate staffing and support. This retrospective case series aims to quantify the CCU care received by patients following total laryngectomy (TL) at a District General Hospital (DGH) and compare patient outcomes in an attempt to inform current practice. Data relating to TL were collected over a 5-year period from 1st January 2010 to 31st December 2015...
2016: International Journal of Otolaryngology
https://www.readbyqxmd.com/read/27737447/optimal-perioperative-care-in-major-head-and-neck-cancer-surgery-with-free-flap-reconstruction-a-consensus-review-and-recommendations-from-the-enhanced-recovery-after-surgery-society
#16
Joseph C Dort, D Gregory Farwell, Merran Findlay, Gerhard F Huber, Paul Kerr, Melissa A Shea-Budgell, Christian Simon, Jeffrey Uppington, David Zygun, Olle Ljungqvist, Jeffrey Harris
Importance: Head and neck cancers often require complex, labor-intensive surgeries, especially when free flap reconstruction is required. Enhanced recovery is important in this patient population but evidence-based protocols on perioperative care for this population are lacking. Objective: To provide a consensus-based protocol for optimal perioperative care of patients undergoing head and neck cancer surgery with free flap reconstruction. Evidence Review: Following endorsement by the Enhanced Recovery After Surgery (ERAS) Society to develop this protocol, a systematic review was conducted for each topic...
October 13, 2016: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/27727461/a-comparison-of-overall-survival-for-patients-with-t4-larynx-cancer-treated-with-surgical-versus-organ-preservation-approaches-a-national-cancer-data-base-analysis
#17
William A Stokes, Bernard L Jones, Shilpa Bhatia, Ayman J Oweida, Daniel W Bowles, David Raben, Julie A Goddard, Jessica D McDermott, Sana D Karam
BACKGROUND: Although laryngectomy is the treatment of choice for patients with T4 larynx cancer, many patients are unable or unwilling to undergo laryngectomy and instead pursue larynx-preservation strategies combining radiotherapy (RT) and chemotherapy. Herein, the authors analyzed the National Cancer Data Base to evaluate overall survival (OS) between patients treated with surgical and organ-preserving modalities. METHODS: The National Cancer Data Base was queried for patients diagnosed from 2004 through 2012 with T4M0 laryngeal cancer who underwent either laryngectomy (surgery) with adjuvant RT (SRT), chemotherapy starting concurrently within 7 days of RT (CCRT), or multiagent induction chemotherapy starting 43 to 98 days before RT (ICRT)...
October 11, 2016: Cancer
https://www.readbyqxmd.com/read/27719794/-the-eb-2%C3%A2-dummy-a-therapeutic-patient-education-tool-in-ent-surgery
#18
Pauline Mezerette, Élise Lefèvre
The day-to-day management and support of patients undergoing a total laryngectomy has led multi-disciplinary nursing teams to create a therapeutic patient education programme aiming to improve the quality of care and the autonomy of these people. In this context, the eb(2®) dummy is an essential tool.
October 2016: Revue de L'infirmière
https://www.readbyqxmd.com/read/27717234/can-temperament-and-character-features-of-patients-predict-alcohol-use-after-laryngectomy
#19
Ayşegül Batıoğlu Karaaltın, Zerrin Binbay, Özgür Yiğit, Zehra Dönmez, Umur Yollu
AIM: Larynx cancer patients usually use alcohol besides tobacco. It has been reported earlier that nearly half of the patients who have undergone laryngectomcy after larynx cancer diagnosis still continue to consume alcohol after the operation. The aim of this study is to compare the mood and character features of patients who do or do not consume alcohol during the post-operative period and thus to be able to predict the patients who will continue their alcohol use at the post-operative period...
September 26, 2016: Clinical Otolaryngology
https://www.readbyqxmd.com/read/27701887/a-typical-but-seldom-recognized-foreign-body-in-the-esophagus-of-a-laryngectomized-patient
#20
Jaime P Rodrigues, Rolando Pinho, Joao Carvalho
A 57-year-old man with a past medical history of total laryngectomy for squamous cell carcinoma of the larynx was admitted to our institution 5 months after the procedure, for surgical resection of a local recurrence of the tumor. In the postoperative period, endoscopically guided placement of a nasogastric tube was scheduled, after previous failed attempts. Upper gastrointestinal endoscopy revealed an anastomotic dehiscence, 13 cm distal to the incisors, and a foreign body penetrating through the esophageal wall, 20cm distal to the incisors...
October 2016: Revista Española de Enfermedades Digestivas
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