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Total laryngectomy

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https://www.readbyqxmd.com/read/28203135/successful-treatment-of-hepatocellular-carcinoma-complicated-by-fanconi-anemia
#1
Koji Takahashi, Eiichiro Suzuki, Masayuki Yokoyama, Masanori Inoue, Toru Wakamatsu, Tomoko Saito, Yuko Kusakabe, Sadahisa Ogasawara, Yoshihiko Ooka, Akinobu Tawada, Yuhei Nagao, Chiaki Nakaseko, Tetsuhiro Chiba
A 42-year-old woman with liver tumors was referred to our hospital. Her condition was complicated by Fanconi anemia, and she had undergone total laryngectomy 8 years ago. On admission, contrast-enhanced computed tomography revealed hypervascular tumors in the right hepatic lobe. Ultrasound-guided tumor biopsy revealed that the tumor comprised moderately differentiated hepatocellular carcinoma. Although the patient exhibited preserved liver function (Child-Pugh A), complete blood count revealed severe pancytopenia...
January 2017: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/28196713/acellular-dermal-graft-pharyngeal-repair-augmentation-after-laryngectomy
#2
Patrik Pipkorn, Parul Sinha, Joseph Zenga, Evan Graboyes, Bruce H Haughey
PURPOSE: Pharyngocutaneous fistula (PCF) after laryngectomy continues to be a serious complication, especially after radiation. Recruitment of non-radiated tissue into the surgical defect may decrease the risk of fistula. These techniques however have significant morbidity and increases operative time. We hypothesized that using acellular dermal graft to reinforce the pharyngeal closure could decrease the risk of fistula, without the added morbidity of a vascularized flap. METHODS: We performed a retrospective chart review of all patients that underwent a laryngectomy between 2005 and 2015 at an acedemic tertiary referral center...
February 2, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28182267/effect-of-postoperative-radiotherapy-on-survival-for-surgically-managed-pt3n0-and-pt4an0-laryngeal-cancer-analysis-of-the-national-cancer-data-base
#3
Evan M Graboyes, Kevin Y Zhan, Elizabeth Garrett-Mayer, Eric J Lentsch, Anand K Sharma, Terry A Day
BACKGROUND: The current study was conducted to determine the effect of postoperative radiotherapy (PORT) on overall survival in patients with surgically managed pT3-T4aN0 laryngeal squamous cell carcinoma (SCC). METHODS: A review of the National Cancer Data Base from 2004 through 2013 was performed. Patients with surgically managed pT3-4aN0 laryngeal SCC with negative surgical margins were included. Univariable and multivariable Cox regression analyses were used to determine factors associated with survival...
February 9, 2017: Cancer
https://www.readbyqxmd.com/read/28177326/supracricoid-laryngectomy-for-recurrent-laryngeal-cancer-after-chemoradiotherapy-a-systematic-review-and-meta-analysis
#4
C A Leone, P Capasso, D Topazio, G Russo
Residual or recurrent laryngeal cancer after irradiation is a difficult clinical problem with a rate that ranges from 13% to 36% of cases. Supracricoid laryngectomy (SCL) with cricohyoidopexy (CHP) or cricohyoidoepiglottopexy (CHEP) provide reliable oncological and functional results for selected primary and recurrent patients with glottic and supraglottic carcinomas. We conducted a systematic review and meta-analysis to assess the oncological and functional outcomes of patients treated with open partial horizontal laryngectomy types IIa and IIb (CHEP, CHP) in terms of the recurrence of squamocellular cancer of the larynx after radiotherapy failure...
December 2016: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28166547/the-use-of-technology-for-phone-and-face-to-face-communication-after-total-laryngectomy
#5
Jana M Childes, Andrew D Palmer, Melanie Fried-Oken, Donna J Graville
Purpose: The purpose of this article is to describe the characteristics and experiences of individuals who use technology to support telephone or face-to-face communication after total laryngectomy. Method: An online questionnaire was used to identify potential participants. Seventeen individuals met inclusion criteria and participated in an in-depth survey. They were compared with a reference group matched for age, gender, and time postsurgery who did not use these technologies...
February 1, 2017: American Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/28148423/-the-eb-2%C3%A2-dummy-a-therapeutic-patient-education-tool-in-ent-surgery
#6
REVIEW
Pauline Mezerette, Élise Lefèvre
The day-to-day management and support of patients undergoing a total laryngectomy has led multi-disciplinary nursing teams to create a therapeutic patient education programme aiming to improve the quality of care and the autonomy of these people. In this context, the eb(2®) dummy is an essential tool.
October 2016: Revue de L'infirmière
https://www.readbyqxmd.com/read/28145831/commentary-on-shenson-et-al-effect-of-preoperative-counseling-on-hospital-length-of-stay-and-readmissions-after-total-laryngectomy
#7
Jeffrey C Liu
No abstract text is available yet for this article.
February 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28131461/proof-of-concept-of-a-tracheoesophageal-voice-prosthesis-insufflator-for-speech-production-after-total-laryngectomy
#8
Heather Starmer, Russell H Taylor, Salem I Noureldine, Jeremy D Richmon
IMPORTANCE: There may have a variety of reasons why patients are unable to produce tracheoesophageal speech after total laryngectomy (TL) including poor pulmonary reserve or other comorbidities that prevent adequate stoma occlusion and intratracheal pressure to voice. Other patients find it difficult, uncomfortable, or socially awkward to manually occlude the stoma with the finger or thumb. OBJECTIVE: The study aimed to assess the feasibility of achieving TE speech with a prototype TE voice prosthesis insufflator (TEVPI)...
January 25, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28124628/comparison-of-swallowing-outcomes-of-laryngotracheal-separation-versus-total-laryngectomy-in-a-validated-ovine-model-of-profound-oropharyngeal-dysphagia
#9
N N Venkatesan, C M Johnson, M T Siddiqui, D J Cates, M A Kuhn, G N Postma, P C Belafsky
OBJECTIVES: To validate the ovine model of profound oropharyngeal dysphagia and compare swallowing outcomes of laryngotracheal separation with those of total laryngectomy. METHODS: Under real-time fluoroscopy, swallowing trials were conducted using the head and neck of two Dorper cross ewes and one human cadaver, secured in lateral fluoroscopic orientation. Barium trials were administered at baseline, pre- and post-laryngohyoid suspension, following laryngotracheal separation, and following laryngectomy in the ovine model...
January 26, 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28110860/results-of-total-laryngectomy-as-treatment-for-locally-advanced-hypopharyngeal-cancer
#10
Patricia García-Cabo Herrero, Laura Fernández-Vañes, Fernando López Álvarez, César Álvarez Marcos, José Luis Llorente, Juan Pablo Rodrigo
INTRODUCTION AND OBJECTIVES: Total laryngectomy (TL), with eventual postoperative radiotherapy, has proven to be effective in treating cases of locally advanced hypopharyngeal cancer. The aim of this study was to analyse the oncological outcomes of this procedure in patients with hypopharyngeal cancer classified T3 and T4. METHODS: We studied 59 patients (33 T3 and 26 T4a) with primary squamous cell carcinoma of the hypopharynx treated with TL from 1998 to 2012...
January 19, 2017: Acta Otorrinolaringológica Española
https://www.readbyqxmd.com/read/28101206/primary-chondrosarcoma-of-the-thyroid-cartilage-surgery-based-management-of-a-rare-case
#11
Guo-Hua Sun, Yuan-Jin Wang, Li-Li Gao, Ning Qu, Xiang-Ming Mu, Rong-Liang Shi, Qing-Hai Ji
In this study, we present a case of a 52-year-old male with a chondrosarcoma of the left lamina of the thyroid cartilage. Pre-operative evaluations detected typical calcifications and delineated the extent of the tumor. The patient underwent a total laryngectomy to ensure the complete resection of the tumor. The tumor was histopathologically found to consist of chondrocytes in a hyaline cartilage matrix. The patient's post-operative course has been successful apart from the permanent tracheostomy. Herien, we discuss the methods and rationales for the diagnosis and management of and recovery from this rare tumor, and also provide a review of the literature...
December 2016: Oncology Letters
https://www.readbyqxmd.com/read/28095938/effect-of-the-patient-to-patient-communication-model-on-dysphagia-caused-by-total-laryngectomy
#12
L Tian, R An, J Zhang, Y Sun, R Zhao, M Liu
OBJECTIVE: The study aimed to evaluate the effect of a patient-to-patient communication model on dysphagia in laryngeal cancer patients after total laryngectomy. METHODS: Sixty-five patients who had undergone total laryngectomy were randomly divided into three groups: a routine communication group, a patient communication group (that received the patient-to-patient communication model) and a physician communication group. Questionnaires were used to compare quality of life and swallowing problems among all patient groups...
January 18, 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28093768/short-term-and-long-term-follow-up-of-pulmonary-function-in-patients-with-copd-after-total-laryngectomy-a-prospective-study
#13
Charlotte Schönwald, Maria Isabel Körber, Dirk Beutner, Roman Pfister, Konrad Frank, Orlando Guntinas-Lichius, Guido Michels
OBJECTIVE: There exists no standardized method for examining lung function in laryngectomized patients. STUDY DESIGN AND METHODS: We established a base plate adapter (BPA) system for patients after laryngectomy. In 10 patients with chronic obstructive pulmonary disease (COPD), we evaluated pulmonary function before laryngectomy, as well as 2 weeks and 3 months after laryngectomy. RESULTS: The BPA system was well tolerated and delivered reliable results comparable to measurements with a mouthpiece...
January 17, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28054142/extent-of-thyroid-resection-and-thyroid-function-after-postoperative-radiotherapy-following-total-laryngectomy-or-total-pharyngo-laryngo-esophagectomy
#14
Kiyoaki Tsukahara, Rio Kojima, Ray Motohashi, Takuro Okada, Masanori Yatomi, Yasuaki Katsube, Atsuo Takeda, Ayumi Agata, Yasuo Ogawa
OBJECTIVE: Concurrent chemoradiotherapy (CCRT) is often performed after total pharyngo-laryngo-esophagectomy (TPLE) or total laryngectomy (TL). Hypothyroidism is one of the side-effects of CCRT. The objective of this study was to ascertain the timing of onset and severity of latent hypothyroidism among patients who underwent radiotherapy (RT) or CCRT after TPLE or TL, using thyroid-stimulating hormone (TSH) as a biomarker, and to explore methods of preventing its development. METHODS: Participants comprised 21 patients who underwent these treatments at Tokyo Medical University Hachioji Medical Center between May 2009 and December 2013...
January 4, 2017: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28052218/implantation-of-an-artificial-larynx-after-total-laryngectomy
#15
LETTER
Christian Debry, N Engin Vrana, Agnès Dupret-Bories
No abstract text is available yet for this article.
5, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28052013/association-of-genetic-polymorphisms-with-laryngeal-carcinoma-prognosis-in-a-chinese-population
#16
Fang Quan, Feipeng Zhang, Yanxia Bai, Long Zhou, Hua Yang, Bin Li, Tianbo Jin, Huajing Li, Yuan Shao
We analyzed the effects of single-nucleotide polymorphisms (SNPs) on laryngeal carcinoma (LC) risk and overall survival (OS) in 170 Chinese male LC patients followed for 10 years. After assessment of clinical characteristics (age, laryngectomy, neck dissection, tumor differentiation, TNM status), the patients were genotyped for 24 SNPs associated with risk in multiple cancers. LC risk was assessed using log-rank test and Cox proportional hazard models. The median OS time was 48 months. By the follow-up deadline, OS was 41...
December 30, 2016: Oncotarget
https://www.readbyqxmd.com/read/28049900/effect-of-medical-educational-lectures-by-pharmacists-for-understanding-and-relieving-post-laryngectomy-symptoms
#17
Naomi Hyoguchi, Toshio Kubota, Daisuke Kobayashi, Takao Shimazoe
 Patients who underwent total laryngectomy (TL) are limited in their access to health information and have reduced quality of life because of difficulties in communicating with health providers. Understanding the method for coping with symptoms after TL is important to self-control. However, their understanding and relief regarding the method including medicine use are not well known. In this study, we conducted a current situation survey about symptoms after TL and held medical educational lectures (ML) by pharmacists for the patients...
2017: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/28033526/induction-chemotherapy%C3%A2-followed-by-radiotherapy-for-larynx-preservation-in-advanced-laryngeal-and-hypopharyngeal-cancer-outcome-prediction-after-one-cycle-induction-chemotherapy-by-a-score-based-on-clinical-evaluation-computed-tomography-based-volumetry%C3%A2-and
#18
Gunnar Wichmann, Anne Krüger, Andreas Boehm, Marlen Kolb, Mathias Hofer, Milos Fischer, Stefan Müller, Sandra Purz, Patrick Stumpp, Osama Sabri, Andreas Dietz, Regine Kluge
BACKGROUND: Long-term laryngectomy-free (LFS), tumour-specific (TSS) and overall survival (OS) is achieved by non-surgical larynx preservation (LP) only in a proportion of patients with locally advanced laryngeal or hypopharyngeal cancer. A score facilitating decision-making after 1 cycle induction chemotherapy (IC-1) may improve LFS and TSS. METHODS: Early response to IC-1 with TPF ± cetuximab was assessed in 52 patients using endoscopic tumour staging for selecting total laryngectomy for non-responders with endoscopic tumour surface shrinkage <30% versus induction chemotherapy plus radiotherapy (IC + RT) for responders...
December 26, 2016: European Journal of Cancer
https://www.readbyqxmd.com/read/28026864/complications-hospital-length-of-stay-and-readmission-after-total-laryngectomy
#19
Ryan P Goepfert, Katherine A Hutcheson, Jan S Lewin, Neha G Desai, Mark E Zafereo, Amy C Hessel, Carol M Lewis, Randal S Weber, Neil D Gross
BACKGROUND: The purpose of this study was to describe the 30-day incidence of complications after total laryngectomy (TL) in a high-volume institution and their impact on the hospital length of stay (LOS) and readmission rates. METHODS: A retrospective cohort study of all patients who underwent TL at The University of Texas MD Anderson Cancer Center from January 1, 2010 through June 30, 2013 was conducted. The patient demographics, treatment history, LOS, and 30-day post-TL complications and readmissions were extracted from the medical record...
December 27, 2016: Cancer
https://www.readbyqxmd.com/read/28025603/evidence-and-evidence-gaps-of-laryngeal-cancer-surgery
#20
REVIEW
Susanne Wiegand
Surgical treatment of laryngeal cancer has been established for decades. In addition to total laryngectomy, which was first performed in 1873, a large number or organ preservation surgical techniques, like open partial laryngectomy, transoral laser microsurgery, and transoral robotic surgery have been developed. Studies on laryngeal cancer surgery are mainly retrospective case series and cohort studies. The evolution of chemoradiation protocols and their analysis in prospective randomized trials have led to an increasing acceptance of non-surgical treatment procedures...
2016: GMS Current Topics in Otorhinolaryngology, Head and Neck Surgery
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