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https://www.readbyqxmd.com/read/28820061/renin-angiotensin-system-and-cytokines-in-chronic-kidney-disease-clinical-and-experimental-evidence
#1
Ariadna Andrade Saldanha Silva, Beranardo Bahia Finotti, Amanda Oliveira Lauar, Thiago Ruiz Rodrigues Prestes, Ana Cristina Simões E Silva
Chronic kidney disease (CKD) has become a major public health problem in Brazil and worldwide. There are many causes of CKD, being the congenital anomalies of the kidney and urinary tract and the glomerular diseases very common in pediatric patients, while diabetic nephropathy, CKD due to chronic arterial hypertension and glomerular diseases are predominant in adult patients. Many endogenous mediators have been related to the pathophysiology of CKD, being relevant the effects of the renin-angiotensin system (RAS) and the immune-inflammatory mediators including cytokines...
August 18, 2017: Protein and Peptide Letters
https://www.readbyqxmd.com/read/28810997/cutaneous-leishmaniasis-in-a-saudi-arabian-soldier-stationed-in-the-united-states
#2
Kelly Laurent, Jason Susong, Eric Fillman, Simon Ritchie
BACKGROUND: Leishmaniasis is a common parasitic disease seen in many parts of the world, especially in areas where current U.S. and international forces are deployed. Approximately 350 million people are thought to be at risk of cutaneous leishmaniasis (CL) with an annual incidence of 1.5 million cases. Over 90% of cutaneous infections with Leishmania occur in the Middle East, Brazil, and Peru. Outbreaks of CL may occur in military personnel deployed to endemic areas. Since the incubation period for symptomatic CL ranges from weeks to months, symptoms may not appear until well after returning to the United States...
July 2017: Military Medicine
https://www.readbyqxmd.com/read/28810682/effects-of-known-determinants-on-methylene-bisphenyl-isocyanate-mdi-concentration-during-spray-on-truck-bed-lining-processes
#3
Nicholas C Schaal, William J Brazile, Katie L Finnie, James P Tiger
Background: Occupational exposure to methylene bisphenyl isocyanate (MDI) presents serious worker health concerns as it may lead to short- and long-term health effects such as asthma, airway irritation, hypersensitivity pneumonitis, and irritation of skin and mucous membranes. While studies of worker isocyanate exposures during vehicle painting activities are widespread, few studies have investigated the spray-on truck bed-liner (STBL) industry. The purpose of this study was to determine the effectiveness of several ventilation system variables and process characteristics in controlling MDI concentrations in the STBL industry...
August 1, 2017: Annals of Work Exposures and Health
https://www.readbyqxmd.com/read/28810175/time-trends-for-prostate-cancer-mortality-in-brazil-and-its-geographic-regions-an-age-period-cohort-analysis
#4
Sonia Faria Mendes Braga, Mirian Carvalho de Souza, Mariangela Leal Cherchiglia
BACKGROUND: In the 1980s, an increase in mortality rates for prostate cancer was observed in North America and developed European countries. In the 1990s, however, mortality rates decreased for these countries, an outcome related to early detection of the disease. Conversely, an upward trend in mortality rates was observed in Brazil. This study describe the trends in mortality for prostate cancer in Brazil and geographic regions (North, Northeast, South, Southeast, and Central-West) between 1980 until 2014 and analyze the influence of age, period, and cohort effects on mortality rates...
August 12, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28806786/an-economic-evaluation-of-vector-control-in-the-age-of-a-dengue-vaccine
#5
Christopher Fitzpatrick, Alexander Haines, Mathieu Bangert, Andrew Farlow, Janet Hemingway, Raman Velayudhan
INTRODUCTION: Dengue is a rapidly emerging vector-borne Neglected Tropical Disease, with a 30-fold increase in the number of cases reported since 1960. The economic cost of the illness is measured in the billions of dollars annually. Environmental change and unplanned urbanization are conspiring to raise the health and economic cost even further beyond the reach of health systems and households. The health-sector response has depended in large part on control of the Aedes aegypti and Ae...
August 14, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28805164/modelling-the-spatial-distribution-of-fasciola-hepatica-in-bovines-using-decision-tree-logistic-regression-and-gis-query-approaches-for-brazil
#6
S C Bennema, M B Molento, R G Scholte, O S Carvalho, I Pritsch
Fascioliasis is a condition caused by the trematode Fasciola hepatica. In this paper, the spatial distribution of F. hepatica in bovines in Brazil was modelled using a decision tree approach and a logistic regression, combined with a geographic information system (GIS) query. In the decision tree and the logistic model, isothermality had the strongest influence on disease prevalence. Also, the 50-year average precipitation in the warmest quarter of the year was included as a risk factor, having a negative influence on the parasite prevalence...
August 14, 2017: Parasitology
https://www.readbyqxmd.com/read/28802822/stillbirth-prevalence-in-brazil-an-exploration-of-regional-differences
#7
Taiana Silva Carvalho, Pat Doyle, Lucia Campos Pellanda
INTRODUCTION: Brazil is a large, heterogeneous, and diverse country, marked by social, economic, and regional inequalities. Stillbirth is a global concern, especially in low- and middle-income countries. This study investigated the prevalence and possible determinants of stillbirth in different regions of Brazil. METHODS: This is a cross-sectional study including all women of reproductive age who had had a pregnancy in the last five years, enrolled in the most recent Brazilian Demographic and Health Survey (DHS/PNDS-2006/07)...
August 9, 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/28793130/time-trends-in-physical-activity-of-adult-users-of-the-brazilian-national-health-system-2010-2014-longitudinal-study
#8
Bruna Camilo Turi, Jamile Sanches Codogno, Rômulo Araújo Fernandes, Kyle Robinson Lynch, Eduardo Kokubun, Henrique Luiz Monteiro
CONTEXT AND OBJECTIVE: In this longitudinal study, we aimed to describe time trends of physical activity (PA) in different domains from 2010 to 2014 among users of the Brazilian National Health System, taking into account the effects of sex, age and economic status (ES). DESIGN AND SETTING: Longitudinal study conducted in five primary care units in Bauru (SP), Brazil. METHODS: The sample was composed of 620 men and women who were interviewed in 2010, 2012 and 2014...
July 2017: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/28793089/-evolution-in-the-use-and-the-expenditures-of-a-healthcare-provider
#9
André Luís de Castro Moura Duarte, Felippe de Medeiros Oliveira, Anderson de Andrade Santos, Bento Fortunato Cardoso Dos Santos
Brazil's aging population and the rising number of people reliant upon the country's supplementary healthcare system have elicited the concern of public and private managers regarding the increase in healthcare costs. In this paper, the costs per gender, per type of medical expenses and per age group of a major Brazilian self-managed healthcare provider between 2007 and 2013 were analyzed. This healthcare provider is of interest because, besides portraying a single condition of revenue growth restricted to the existing contributors, it also replicates the demographic profile expected for Brazil in 2050, when approximately one-third of its population will be over 60 years of age...
August 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28793086/complex-chronic-conditions-in-children-and-adolescents-hospitalizations-in-brazil-2013
#10
Erly Catarina de Moura, Martha Cristina Nunes Moreira, Lívia Almeida Menezes, Isadora Almeida Ferreira, Romeu Gomes
This article aims to estimate the extent of hospitalizations for complex chronic conditions in Brazil. Data from the Hospital Information System for 2013 were compiled according to the International Classification of Diseases 10th Revision. Hospitalization rates were estimated according to region, sex, age and disease chapter, taking into account the 2012 population as a reference, as well the percentage of highly complex procedures and mortality rates. Public hospitals treated 190,000 inpatients in 2013. The rate was highest among the population in the South of Brazil, those who were male and children under the age of one...
August 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28793084/-use-of-medicinal-plants-as-home-remedies-in-primary-health-care-in-blumenau-state-of-santa-catarina-brazil
#11
Ana Lúcia Bertarello Zeni, Amanda Varnier Parisotto, Gerson Mattos, Ernani Tiaraju de Santa Helena
An increase in the use of alternative therapeutic practices has been observed in the past decade, especially in medicinal plants, herbal and home remedies, which has been supported by policies within the scope of the Unified Health System (SUS). This study investigated the use of home remedies by users of Primary Health Care in Blumenau, State of Santa Catarina. It is a cross-sectional, observational and epidemiological study, the data for which were obtained via a questionnaire applied to 701 individuals. An unconditional logistic regression model was used to estimate the association between the use of home remedies and socio-demographic and medical care variables...
August 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28793079/-the-interface-between-primary-and-secondary-care-in-dentistry-in-the-unified-health-system-sus-an-integrative-systematic-review
#12
Helbert Eustáquio Cardoso da Silva, Leila Bernarda Donato Gottems
Secondary care in dentistry in Brazil has scarce and broadly underutilized resources. The challenge is to organize the interface between primary health care (PHC) and secondary care in order to consolidate the population's access to specialist dental care in the Unified Health System (SUS). This article seeks to analyze national publications in Portuguese and English on the interface between secondary health care and primary health care in dentistry from the perspective of comprehensive care in the SUS. It is an integrative review, considering the publications of the following databases: SciELO (Scientific Electronic Library Online), LILACS (Latin American and Caribbean Literature) WEB OF SCIENCE, SCOPUS, PubMed (International Literature on Health Sciences) and GOOGLE SCHOLAR...
August 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28793067/farm%C3%A3-cia-popular-program-pharmaceutical-market-analysis-of-antihypertensive-acting-on-the-renin-angiotensin-system-medicines
#13
Rondineli Mendes da Silva, Gabriela Costa Chaves, Luisa Arueira Chaves, Mônica Rodrigues Campos, Vera Lucia Luiza, Andréa Dâmaso Bertoldi, Dennis Ross-Degnan, Isabel Cristina Martins Emmerick
This paper aims to analyse changes in the retail pharmaceutical market following policy changes in the Farmácia Popular Program (FP), a medicines subsidy program in Brazil. The retrospective longitudinal analyses focus on therapeutic class of agents acting on the renin-angiotensin system. Data obtained from QuintilesIMS (formerly IMS Health) included private retail pharmacy sales volume (pharmaceutical units) and sales values from 2002 to 2013. Analyses evaluated changes in market share following key FP policy changes...
August 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28793026/epidemiological-study-of-scorpion-stings-in-the-rio-grande-do-norte-state-northeastern-brazil
#14
Kaliany Adja Medeiros de Araújo, Aluska Vieira Tavares, Michael Radan de Vasconcelos Marques, Alecxandro Alves Vieira, Renner de Souza Leite
This communication is a retrospective epidemiological study of the scorpion sting cases recorded from 2007 to 2014 in the Rio Grande do Norte State, Northeastern Brazil. The data was collected from the Injury Notification Information System database of the Health Department of Rio Grande do Norte State. A total of 20,555 cases were studied. The cases were distributed over all months of the period studied and occurred mainly in urban areas. Victims were predominantly 20-29 year-old women. Most victims were stung on the foot and received medical care within 1-3 h after being stung...
August 7, 2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/28793021/the-epidemiology-of-snakebite-in-the-rio-grande-do-norte-state-northeastern-brazil
#15
Aluska Vieira Tavares, Kaliany Adja Medeiros de Araújo, Michael Radan de Vasconcelos Marques, Alecxandro Alves Vieira, Renner de Souza Leite
This report is a retrospective study of the epidemiology of snakebite cases recorded from 2007 to 2014 in the Rio Grande do Norte State, northeastern Brazil. Data was collected from the Injury Notification Information System database of the Health Department of Rio Grande do Norte. A total of 3,019 cases were studied. Cases were distributed over all months of the period studied and occurred mainly in rural areas. Snakes of the genus Bothrops, Crotalus, Micrurus, Lachesis and non-venomous snakes were responsible for 1,507, 185, 52, 6 and 673 cases, respectively...
2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/28792987/-infant-mortality-according-to-color-or-race-based-on-the-2010-population-census-and-national-health-information-systems-in-brazil
#16
Aline Diniz Rodrigues Caldas, Ricardo Ventura Santos, Gabriel Mendes Borges, Joaquim Gonçalves Valente, Margareth Crisóstomo Portela, Gerson Luiz Marinho
The aim of this study was to investigate infant mortality data according to color or race in Brazil with a focus on indigenous individuals, based on data from the 2010 Population Census and the Brazilian Mortality Information System (SIM) and Brazilian Information System on Live Births (SINASC). In both sources, the infant mortality rate (IMR) for indigenous individuals was the highest of all the various population segments. Although the census data indicate inequalities by color or race, the infant mortality rates for indigenous and black individuals were lower than those based on data from SIM/SINASC...
August 7, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/28792514/network-analysis-for-science-and-technology-management-evidence-from-tuberculosis-research-in-fiocruz-brazil
#17
Bruna de Paula Fonseca E Fonseca, Marcus Vinicius Pereira da Silva, Kizi Mendonça de Araújo, Ricardo Barros Sampaio, Milton Ozório Moraes
Collaborative networks are of great value for science and technology (S&T) institutions as a way of sharing, generating and disseminating new knowledge that could ultimately lead to innovations. Driven by the need to assess the contribution and effectiveness of these networks in informing S&T management, we explored the evolution and dynamics of tuberculosis scientific networks involving the Oswaldo Cruz Foundation (Fiocruz), the major public health S&T Institution in Brazil. Social network analysis (SNA) was used to produce a 10-year (2005-2009, 2010-2014) retrospective longitudinal mapping of Brazilian tuberculosis research networks within the country and internationally, highlighting Fiocruz collaborations...
2017: PloS One
https://www.readbyqxmd.com/read/28783857/trends-in-the-prevalence-of-live-macrosomic-newborns-according-to-gestational-age-strata-in-brazil-2001-2010-and-2012-2014
#18
Maria Isabel do Nascimento, Daniele Francine Pereira, Calliana Lopata, Carina Ladeia Flores Oliveira, Ariane Arruda de Moura, Maria Júlia da Silva Mattos, Lucas Saraiva da Silva
Purpose To describe the trends in the prevalence of macrosomia (birth weight ≥ 4,000 g) according to gestational age in Brazil in the periods of 2001-2010 and 2012-2014. Methods Ecological study with data from the Brazilian Live Birth Information System (SINASC, in the Portuguese acronym) regarding singleton live newborns born from 22 gestational weeks. The trends in Brazil as a whole and in each of its five regions were analyzed according to preterm (22-36 gestational weeks) and term (37-42 gestational weeks) strata...
August 2017: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/28783598/economic-human-and-environmental-health-benefits-of-replacing-formaldehyde-in-the-preservation-of-corpses
#19
Jussara Rocha Ferreira, Lorenna Cardoso Rezende, Abel De Souza Barbosa, Phellip De Carvalho, Natácia Evangelista De Lima, Alexandre Assis Carvalho
Formaldehyde has been prominent in preserving biological tissues since the nineteenth century. Despite being admittedly harmful to health and to the environment, it is still widely used. The Morphology Department of the University of Brasília - Brazil, applied the rethink, reduce, reuse, recycle and responsibility methodology to their activities in an effort to protect the health of laboratory workers and users, save resources and reduce damage to the environment. Here we evaluate the results obtained a decade after the implementation of this proposal (2005-2015)...
August 4, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28780524/the-rise-of-reimbursement-based-medicine-the-case-of-bone-metastasis-radiation-treatment
#20
Marcos Santos, Jan Helge Solbakk, Volnei Garrafa
It has been hypothesised that the reimbursement system pertaining to radiotherapy is influencing prescription practices for patients with cancer with bone metastases. In this paper, we present and discuss the results of an empirical study that was undertaken on patient records, referred to radiotherapy for the treatment of bone metastases, in a medium-size city, in southern Brazil, during the period of March 2006 to March 2014. Our findings seem to confirm this hypothesis: after a change in the reimbursement method, radiation prescriptions were adapted accordingly, in order to maximise profits...
August 5, 2017: Journal of Medical Ethics
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