keyword
MENU ▼
Read by QxMD icon Read
search

Track and

keyword
https://www.readbyqxmd.com/read/28823103/bariatric-surgery-is-accompanied-by-changes-in-extracellular-vesicle-associated-and-plasma-fatty-acid-binding-protein-4
#1
Justyna K Witczak, Thinzar Min, Sarah L Prior, Jeffrey W Stephens, Philip E James, Aled Rees
BACKGROUND: Bariatric surgery markedly reduces fat mass with beneficial effects on cardiometabolic health but the mechanisms involved are not fully understood. Extracellular vesicles (EVs) are secreted by a variety of cells, including adipocytes, and may mediate some of these benefits. However, the effects of bariatric surgery on circulating EVs are unclear. METHODS: Concentration of plasma EVs isolated by ultracentrifugation at baseline, 1 and 6 months post-bariatric surgery (n = 20) was established using Nanoparticle Tracking Analysis...
August 19, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28823070/-what-is-not-written-does-not-exist-the-importance-of-proper-documentation-of-medication-use-history
#2
Carina Carvalho Silvestre, Lincoln Marques Cavalcante Santos, Alfredo Dias de Oliveira-Filho, Divaldo Pereira de Lyra
Medications are perceived as health risk factors, because they might cause damage if used improperly. In this context, an adequate assessment of medication use history should be encouraged, especially in transitions of care to avoid unintended medication discrepancies (UMDs). In a case-controlled study, we investigated potential risk factors for UMDs at hospital admission and found that 150 (42%) of the 358 patients evaluated had one or more UMDs. We were surprised to find that there was no record of a patient and/or relative interview on previous use of medication in 117 medical charts of adult patients (44...
August 19, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28822780/global-yellow-fever-vaccination-coverage-from-1970-to-2016-an-adjusted-retrospective-analysis
#3
Freya M Shearer, Catherine L Moyes, David M Pigott, Oliver J Brady, Fatima Marinho, Aniruddha Deshpande, Joshua Longbottom, Annie J Browne, Moritz U G Kraemer, Kathleen M O'Reilly, Joachim Hombach, Sergio Yactayo, Valdelaine E M de Araújo, Aglaêr A da Nóbrega, Jonathan F Mosser, Jeffrey D Stanaway, Stephen S Lim, Simon I Hay, Nick Golding, Robert C Reiner
BACKGROUND: Substantial outbreaks of yellow fever in Angola and Brazil in the past 2 years, combined with global shortages in vaccine stockpiles, highlight a pressing need to assess present control strategies. The aims of this study were to estimate global yellow fever vaccination coverage from 1970 through to 2016 at high spatial resolution and to calculate the number of individuals still requiring vaccination to reach population coverage thresholds for outbreak prevention. METHODS: For this adjusted retrospective analysis, we compiled data from a range of sources (eg, WHO reports and health-service-provider registeries) reporting on yellow fever vaccination activities between May 1, 1939, and Oct 29, 2016...
August 16, 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28822770/regulation-of-autoimmune-myocarditis-by-host-responses-to-the-microbiome
#4
Jobert G Barin, Monica V Talor, Nicola L Diny, SuFey Ong, Julie A Schaub, Elizabeth Gebremariam, Djahida Bedja, Guobao Chen, Hee Sun Choi, Xuezhou Hou, Lei Wu, Ashley B Cardamone, Daniel A Peterson, Noel R Rose, Daniela Čiháková
The extensive, diverse communities that constitute the microbiome are increasingly appreciated as important regulators of human health and disease through inflammatory, immune, and metabolic pathways. We sought to elucidate pathways by which microbiota contribute to inflammatory, autoimmune cardiac disease. We employed an animal model of experimental autoimmune myocarditis (EAM), which results in inflammatory and autoimmune pathophysiology and subsequent maladaptive cardiac remodeling and heart failure. Antibiotic dysbiosis protected mice from EAM and fibrotic cardiac dysfunction...
August 16, 2017: Experimental and Molecular Pathology
https://www.readbyqxmd.com/read/28822669/left-ventricular-lead-position-guided-by-parametric-strain-echocardiography-improves-response-to-cardiac-resynchronization-therapy
#5
Donato Mele, Marianna Nardozza, Michele Malagù, Emanuela Leonetti, Cristina Fragale, Antonio Rondinella, Roberto Ferrari, Matteo Bertini
BACKGROUND: There is still a significant proportion of patients with heart failure who fail to improve after cardiac resynchronization therapy (CRT). The investigators used parametric two-dimensional speckle-tracking echocardiography with polar plots of the amplitude and timing of left ventricular (LV) longitudinal strain to guide implantation of the LV lead, with the aim of increasing CRT response. METHODS: Sixty-four patients who underwent LV lead implantation guided by two-dimensional speckle-tracking echocardiography (study group) and 64 patients treated with standard CRT implantation (control group) were retrospectively analyzed in this study...
August 16, 2017: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/28822624/evaluating-an-australian-emergency-nurse-practitioner-candidate-training-program
#6
Sharyn J Plath, Mary Wright, Julia Hocking
Nurse Practitioners (NPs) receive core clinical training at master's level, with their employer providing the opportunity to upskill in clinical and procedural competencies. It is increasingly recognised that this generic education requires supplementary training for operating effectively within a specific clinical environment. In this paper we describe a pilot program designed to train Australian NP Candidates to work effectively within the Emergency Department Fast Track model of care. The training program consisted of a 12-month period: four hours in-house training per week over two semesters, running concurrently with the NP candidate's University semesters, and 3 months' clinical practice to consolidate...
August 16, 2017: Australasian Emergency Nursing Journal: AENJ
https://www.readbyqxmd.com/read/28822473/influence-of-spinal-manipulative-therapy-force-magnitude-and-application-site-on-spinal-tissue-loading-a-biomechanical-robotic-serial-dissection-study-in-porcine-motion-segments
#7
Martha Funabashi, François Nougarou, Martin Descarreaux, Narasimha Prasad, Greg Kawchuk
OBJECTIVE: In order to define the relation between spinal manipulative therapy (SMT) input parameters and the distribution of load within spinal tissues, the aim of this study was to determine the influence of force magnitude and application site when SMT is applied to cadaveric spines. METHODS: In 10 porcine cadavers, a servo-controlled linear actuator motor provided a standardized SMT simulation using 3 different force magnitudes (100N, 300N, and 500N) to 2 different cutaneous locations: L3/L4 facet joint (FJ), and L4 transverse processes (TVP)...
July 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/28822105/peer-led-small-groups-are-we-on-the-right-track
#8
Fraser Moore
INTRODUCTION: Peer tutor-led small group sessions are a valuable learning strategy but students may lack confidence in the absence of a content expert. This study examined whether faculty reinforcement of peer tutor-led small group content was beneficial. METHODS: Two peer tutor-led small group sessions were compared with one faculty-led small group session using questionnaires sent to student participants and interviews with the peer tutors. One peer tutor-led session was followed by a lecture with revision of the small group content; after the second, students submitted a group report which was corrected and returned to them with comments...
August 18, 2017: Perspectives on Medical Education
https://www.readbyqxmd.com/read/28821875/convenient-and-effective-icgylation-of-magnetic-nanoparticles-for-biomedical-applications
#9
Hye Sun Park, Jongwoo Kim, Mi Young Cho, Hyunseung Lee, Sang Hwan Nam, Yung Doug Suh, Kwan Soo Hong
Nanoprobes used for biomedical applications usually require surface modifications with amphiphilic surfactants or inorganic coating materials to enhance their biocompatibility. We proposed a facile synthetic approach for the phase transfer of hydrophobic magnetic nanoparticles by the direct adherence of fluorescent probes, without any chemical modifications, for use as a magnetic resonance (MR)/near-infrared (NIR) fluorescence bimodal imaging contrast agent. Indocyanine green (ICG) was used not only as an optical component for NIR imaging, but also as a surfactant for phase transfer with no superfluous moiety: we therefore called the process "ICGylation"...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28821735/current-and-future-suitability-of-wintering-grounds-for-a-long-distance-migratory-raptor
#10
Christina Kassara, Laura Gangoso, Ugo Mellone, Gvido Piasevoli, Thomas G Hadjikyriakou, Nikos Tsiopelas, Sinos Giokas, Pascual López-López, Vicente Urios, Jordi Figuerola, Rafa Silva, Willem Bouten, Alexander N G Kirschel, Munir Z Virani, Wolfgang Fiedler, Peter Berthold, Marion Gschweng
Conservation of migratory species faces the challenge of understanding the ecological requirements of individuals living in two geographically separated regions. In some cases, the entire population of widely distributed species congregates at relatively small wintering areas and hence, these areas become a priority for the species' conservation. Satellite telemetry allows fine tracking of animal movements and distribution in those less known, often remote areas. Through integrating satellite and GPS data from five separated populations comprising most of the breeding range, we created a wide habitat suitability model for the Eleonora's falcon on its wintering grounds in Madagascar...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28821719/neural-physiological-and-behavioral-correlates-of-visuomotor-cognitive-load
#11
S M Hadi Hosseini, Jennifer L Bruno, Joseph M Baker, Andrew Gundran, Lene K Harbott, J Christian Gerdes, Allan L Reiss
Visuomotor ability is quite crucial for everyday functioning, particularly in driving and sports. While there is accumulating evidence regarding neural correlates of visuomotor transformation, less is known about the brain regions that accommodate visuomotor mapping under different cognitive demands. We concurrently measured cortical activity and pupillary response, using functional near infrared spectroscopy (fNIRS) and eye-tracking glasses, to examine the neural systems linked to pupil dilation under varying cognitive demands...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28821661/attenuated-activity-across-multiple-cell-types-and-reduced-monosynaptic-connectivity-in-the-aged-perirhinal-cortex
#12
A P Maurer, S N Burke, K Diba, C A Barnes
The perirhinal cortex (PER), which is critical for associative memory and stimulus discrimination, has been described as a wall of inhibition between the neocortex and hippocampus. With advanced age, rats show deficits on PER-dependent behavioral tasks and fewer PER principal neurons are activated by stimuli, but the role of PER interneurons in these altered circuit properties in old age has not been characterized. In the present study, PER neurons were recorded while rats traversed a circular track bi-directionally in which the track was either empty or contained 8 novel objects evenly spaced around the track...
August 11, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28821634/lipidomic-and-proteomic-analysis-of-exosomes-from-mouse-cortical-collecting-duct-cells
#13
Viet D Dang, Kishore Kumar Jella, Ragy R T Ragheb, Nancy D Denslow, Abdel A Alli
Exosomes are endosome-derived nanovesicles that are involved in cellular communication and signaling. Exosomes are produced by epithelial cells and are found in biologic fluids including blood and urine. The packaged material within exosomes includes proteins and lipids, but the molecular comparison within exosome subtypes is largely unknown. The purpose of this study was to investigate differences between exosomes derived from the apical plasma membrane and basolateral plasma membrane of polarized murine cortical collecting duct principal cells...
August 16, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/28821561/zika-virus-activates-de-novo-and-cross-reactive-memory-b-cell-responses-in-dengue-experienced-donors
#14
Thomas F Rogers, Eileen C Goodwin, Bryan Briney, Devin Sok, Nathan Beutler, Alexander Strubel, Rebecca Nedellec, Khoa Le, Michael E Brown, Dennis R Burton, Laura M Walker
Zika virus (ZIKV) shares a high degree of homology with dengue virus (DENV), suggesting that preexisting immunity to DENV could affect immune responses to ZIKV. We have tracked the evolution of ZIKV-induced B cell responses in three DENV-experienced donors. The acute antibody (plasmablast) responses were characterized by relatively high somatic hypermutation and a bias toward DENV binding and neutralization, implying the early activation of DENV clones. A DENV-naïve donor in contrast showed a classical primary plasmablast response...
August 18, 2017: Science Immunology
https://www.readbyqxmd.com/read/28821437/particle-sizing-of-pharmaceutical-aerosols-via-direct-imaging-of-particle-settling-velocities
#15
Rami Fishler, Frank Verhoeven, Wilbur de Kruijf, Josué Sznitman
We present a novel method for characterizing in near real-time the aerodynamic particle size distributions from pharmaceutical inhalers. The proposed method is based on direct imaging of airborne particles followed by a particle-by-particle measurement of settling velocities using image analysis and particle tracking algorithms. Due to the simplicity of the principle of operation, this method has the potential of circumventing potential biases of current real-time particle analyzers (e.g. Time of Flight analysis), while offering a cost effective solution...
August 16, 2017: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28821002/modeling-the-fate-and-transport-of-17%C3%AE-estradiol-in-the-south-river-watershed-in-virginia
#16
Xiaomin Zhao, Wu-Seng Lung
Hormones excreted by livestock metabolisms often enter surface water through feces and urine and can potentially cause adverse impacts to aquatic biota. This study involved a modeling analysis of 17β-estradiol (E2), a prevalent estrogen, in the South River watershed located in Augusta County, Virginia from 2013 to 2015. Cattle manure, poultry litter, biosolids, septic systems, and wastewater treatment plants (WWTPs) were considered as sources of E2 in this study. The EPA's BASINS modeling framework was configured to track the fate and transport of E2...
August 13, 2017: Chemosphere
https://www.readbyqxmd.com/read/28820891/scene-text-detection-via-extremal-region-based-double-threshold-convolutional-network-classification
#17
Wei Zhu, Jing Lou, Longtao Chen, Qingyuan Xia, Mingwu Ren
In this paper, we present a robust text detection approach in natural images which is based on region proposal mechanism. A powerful low-level detector named saliency enhanced-MSER extended from the widely-used MSER is proposed by incorporating saliency detection methods, which ensures a high recall rate. Given a natural image, character candidates are extracted from three channels in a perception-based illumination invariant color space by saliency-enhanced MSER algorithm. A discriminative convolutional neural network (CNN) is jointly trained with multi-level information including pixel-level and character-level information as character candidate classifier...
2017: PloS One
https://www.readbyqxmd.com/read/28820594/on-the-restrained-proton-indicator-in-combined-quantum-mechanics-molecular-mechanics-dynamics-simulations-of-proton-transfer-through-a-carbon-nanotube
#18
Adam W Duster, Hai Lin
Recently, a collective variable "proton indicator" was purposed for tracking an excess proton solvated in bulk water in molecular dynamics simulations. In this work, we demonstrate the feasibility of utilizing the position of this proton indicator as a reaction coordinate to model an excess proton migrating through a hydrophobic carbon nanotube in combined quantum-mechanics/molecular-mechanics simulations. Our results indicate that applying a harmonic restraint to the proton indicator in the bulk solvent near the nanotube pore entrance leads to the recruitment of water molecules into the pore...
August 18, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28820510/implementation-and-use-of-a-patient-symptom-diary-during-chemotherapy-a-mixed-methods-evaluation-of-the-nurse-perspective
#19
Annemarie Coolbrandt, Erika Bruyninckx, Chris Verslype, Ester Steffens, Ellen Vanhove, Hans Wildiers, Koen Milisen
PURPOSE/OBJECTIVES: To gain a deeper understanding of nurses' experience working with a patient diary for tracking and treating side effects during chemotherapy.
. DESIGN: A mixed-methods design was used to learn about oncology nurses' use and perceptions of a symptom diary. 
. SETTING: Six oncology wards and two outpatient clinics at the University Hospitals Leuven, Belgium.
. SAMPLE: 79 nurses completed a survey, and 14 nurses participated in focus group discussions...
September 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/28820463/cycle-tracks-and-parking-environments-in-china-learning-from-college-students-at-peking-university
#20
Changzheng Yuan, Yangbo Sun, Jun Lv, Anne C Lusk
China has a historic system of wide cycle tracks, many of which are now encroached by cars, buses and bus stops. Even with these conditions, college students still bicycle. On campuses, students park their bikes on facilities ranging from kick-stand-plazas to caged sheds with racks, pumps and an attendant. In other countries, including Canada, some of the newer cycle tracks need to be wider to accommodate an increasing number of bicyclists. Other countries will also need to improve their bike parking, which includes garage-basement cages and two-tiered racks...
August 18, 2017: International Journal of Environmental Research and Public Health
keyword
keyword
59032
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"