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https://www.readbyqxmd.com/read/29241208/exosomes-from-mir-126-overexpressing-adscs-are-therapeutic-in-relieving-acute-myocardial-ischaemic-injury
#1
Qiancheng Luo, Dongfeng Guo, Guorong Liu, Guo Chen, Min Hang, Mingming Jin
BACKGROUND/AIMS: Recent studies have indicated that exosomes play an important role in adipose-derived stem cell (ADSC) transplant-mediated ischaemic heart disease therapy. However, the treatment effect is not obvious. The aim of this study is to investigate whether ADSC-derived exosomes enriched with microRNA (miR)-126 have a more protective effect on acute myocardial infarction (AMI). METHODS: Exosomes were characterized by transmission electron microscopy, and the exosome particles were further examined using nanoparticle tracking analyses...
December 12, 2017: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/29241137/improving-post-detonation-energetics-residues-estimations-for-the-life-cycle-environmental-assessment-process-for-munitions
#2
Michael Walsh, Brian Gullett, Marianne Walsh, Matthew Bigl, Johanna Aurell
The Life Cycle Environmental Assessment (LCEA) process for military munitions tracks possible environmental impacts incurred during all phases of the life of a munition. The greatest energetics-based emphasis in the current LCEA process is on manufacturing. A review of recent LCEAs indicates that energetics deposition on ranges from detonations and disposal during training is only peripherally examined through assessment of combustion products derived from closed-chamber testing or models. These assessments rarely report any measurable energetic residues...
November 15, 2017: Chemosphere
https://www.readbyqxmd.com/read/29240659/using-a-wireless-electroencephalography-device-to-evaluate-e-health-and-e-learning-interventions
#3
Tanya Mailhot, Patrick Lavoie, Marc-André Maheu-Cadotte, Guillaume Fontaine, Alexis Cournoyer, José Côté, France Dupuis, Thierry Karsenti, Sylvie Cossette
BACKGROUND: Measuring engagement and other reactions of patients and health professionals to e-health and e-learning interventions remains a challenge for researchers. OBJECTIVE: The aim of this pilot study was to assess the feasibility and acceptability of using a wireless electroencephalography (EEG) device to measure affective (anxiety, enjoyment, relaxation) and cognitive (attention, engagement, interest) reactions of patients and healthcare professionals during e-health or e-learning interventions...
January 2018: Nursing Research
https://www.readbyqxmd.com/read/29240544/expected-time-to-return-to-athletic-participation-after-stress-fracture-in-division-i-collegiate-athletes
#4
Timothy L Miller, Marissa Jamieson, Sonsecharae Everson, Courtney Siegel
BACKGROUND: Few studies have documented expected time to return to athletic participation after stress fractures in elite athletes. HYPOTHESIS: Time to return to athletic participation after stress fractures would vary by site and severity of stress fracture. STUDY DESIGN: Retrospective cohort study. LEVEL OF EVIDENCE: Level 3. METHODS: All stress fractures diagnosed in a single Division I collegiate men's and women's track and field/cross-country team were recorded over a 3-year period...
December 1, 2017: Sports Health
https://www.readbyqxmd.com/read/29239984/profiling-inflammatory-markers-during-the-competitive-season-and-post-season-in-collegiate-wrestlers
#5
Joe Roth, Taylor Szczygiel, Mary Moore, Paul O'Connor, Jeffrey Edwards, Naveen Sharma, Ryan Pettit-Mee, Micah Zuhl
The purpose of this study was to determine if biological markers of muscle damage and inflammation coincide with subjective measures of muscle fatigue and sleep quality among Division I collegiate wrestlers. The goal was to provide practitioners with noninvasive techniques to evaluate a wrestlers inflammatory state. METHODS: Subjects from the Central Michigan University Division I collegiate wrestling team (n=6) were analyzed on six separate occasions throughout the course of the competitive season and post season...
December 11, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29239911/monitoring-student-immunization-screening-and-training-records-for-clinical-compliance-an-innovative-use-of-the-institutional-learning-management-system
#6
Julie Kientz Elting
Clinical compliance for nursing students is a complex process mandating them to meet facility employee occupational health requirements for immunization, screening, and training prior to patient contact. Nursing programs monitor clinical compliance with in-house management of student records, either paper or electronic, or by contracting with a vendor specializing in online record tracking. Regardless of method, the nursing program remains fully accountable for student preparation and bears the consequences of errors...
December 13, 2017: Nursing Education Perspectives
https://www.readbyqxmd.com/read/29239748/validation-of-an-alignment-method-using-motion-tracking-system-for-in-vitro-orientation-of-cadaveric-hip-joints-with-reduced-set-of-anatomical-landmarks
#7
Suzan Bsat, Ifaz Haider, Andrew Speirs, Paul Beaulé, Hanspeter Frei
Accurate in-vitro orientation of cadaveric hip joints is challenging due to limited available anatomical landmarks. Published hip joint in-vitro investigations commonly lack details on methods used to achieve reported orientations and the accuracy with which the desired orientation has been achieved. The aim of this study was to develop an accurate method for orienting hip joints with limited anatomical landmarks for in-vitro investigations, and to compare this method against orientation using guiding axes and by visual approximation...
November 25, 2017: Medical Engineering & Physics
https://www.readbyqxmd.com/read/29239725/t-cell-calcium-dynamics-visualized-in-a-ratiometric-tdtomato-gcamp6f-transgenic-reporter-mouse
#8
Tobias X Dong, Shivashankar Othy, Amit Jairaman, Jonathan Skupsky, Angel Zavala, Ian Parker, Joseph L Dynes, Michael D Cahalan
Calcium is an essential cellular messenger that regulates numerous functions in living organisms. Here we describe development and characterization of 'Salsa6f', a fusion of GCaMP6f and tdTomato optimized for cell tracking while monitoring cytosolic Ca2+, and a transgenic Ca2+ reporter mouse with Salsa6f targeted to the Rosa26 locus for Cre-dependent expression in specific cell types. The development and function of T cells was unaffected in Cd4-Salsa6f mice. We describe Ca2+ signals reported by Salsa6f during T cell receptor activation in naïve T cells, helper Th17 T cells and regulatory T cells, and Ca2+ signals mediated in T cells by an activator of mechanosensitive Piezo1channels...
December 14, 2017: ELife
https://www.readbyqxmd.com/read/29239553/detecting-space-time-disease-clusters-with-arbitrary-shapes-and-sizes-using-a-co-clustering-approach
#9
Sami Ullah, Hanita Daud, Sarat C Dass, Habib Nawaz Khan, Alamgir Khalil
Ability to detect potential space-time clusters in spatio-temporal data on disease occurrences is necessary for conducting surveillance and implementing disease prevention policies. Most existing techniques use geometrically shaped (circular, elliptical or square) scanning windows to discover disease clusters. In certain situations, where the disease occurrences tend to cluster in very irregularly shaped areas, these algorithms are not feasible in practise for the detection of space-time clusters. To address this problem, a new algorithm is proposed, which uses a co-clustering strategy to detect prospective and retrospective space-time disease clusters with no restriction on shape and size...
November 6, 2017: Geospatial Health
https://www.readbyqxmd.com/read/29239328/leap-motion-based-virtual-reality-training-for-improving-motor-functional-recovery-of-upper-limbs-and-neural-reorganization-in-subacute-stroke-patients
#10
Zun-Rong Wang, Ping Wang, Liang Xing, Li-Ping Mei, Jun Zhao, Tong Zhang
Virtual reality is nowadays used to facilitate motor recovery in stroke patients. Most virtual reality studies have involved chronic stroke patients; however, brain plasticity remains good in acute and subacute patients. Most virtual reality systems are only applicable to the proximal upper limbs (arms) because of the limitations of their capture systems. Nevertheless, the functional recovery of an affected hand is most difficult in the case of hemiparesis rehabilitation after a stroke. The recently developed Leap Motion controller can track the fine movements of both hands and fingers...
November 2017: Neural Regeneration Research
https://www.readbyqxmd.com/read/29239152/the-safety-and-efficiency-of-a-fast-track-protocol-for-sleeve-gastrectomy-a-team-approach
#11
Sebastiaan J Vreeswijk, Pim W van Rutte, Simon W Nienhuijs, R Arthur Bouwman, J Frans Smulders, Marc P Buise
BACKGROUND: Increasing numbers of morbid obese patients has led to increased numbers of bariatric procedures. Fast-track protocols are being developed to enhance the available resources, while maintaining a safe procedure. Reported results on safety merely apply to a mixed bariatric population. The objective was to evaluate safety and efficiency of the fast-track principles in patients undergoing sleeve gastrectomy. METHODS: Retrospective observational study including patients undergoing primary sleeve gastrectomy at the Obesity Centre of the Catharina Hospital Eindhoven, the Netherlands...
December 13, 2017: Minerva Anestesiologica
https://www.readbyqxmd.com/read/29239028/recovery-of-myocardial-mechanics-in-kawasaki-disease-demonstrated-by-speckle-tracking-and-tissue-doppler-methods
#12
Emine Azak, Ibrahim Ilker Cetin, Hazım A Gursu, Ayse Esin Kibar, Murat Surucu, Ali Orgun, Utku Pamuk
AIM: To investigate myocardial deformation and function during treatment for Kawasaki disease (KD) in children. METHODS: We performed speckle tracking echocardiography (STE) and tissue Doppler imaging (TDI) in 15 children with KD and 15 healthy children during treatment for KD. STE was performed for longitudinal and circumferential strain (S) and strain rate (SR) at the left ventricle (LV) and for longitudinal S and SR at the right ventricle (RV). TDI was performed at the base of interventricular septum (IVS), LV, and RV...
December 13, 2017: Echocardiography
https://www.readbyqxmd.com/read/29238958/parasites-driving-host-diversity-incidence-of-disease-correlated-with-daphnia-clonal-turnover
#13
Patrick Turko, Christoph Tellenbach, Esther Keller, Nadine Tardent, Barbara Keller, Piet Spaak, Justyna Wolinska
According to the Red Queen hypothesis, clonal diversity in asexual populations could be maintained by negative frequency-dependant selection by co-evolving parasites. If common clones are selected against and rare clones gain a concomitant advantage, we expect that clonal turnover should be faster during parasite epidemics than between them. We tested this hypothesis exploring field data of the Daphnia - Caullerya host-parasite system. The clonal make-up and turnover of the Daphnia host population was tracked with high temporal resolution from 1998 until 2013, using first allozyme and later microsatellite markers...
December 14, 2017: Evolution; International Journal of Organic Evolution
https://www.readbyqxmd.com/read/29238912/hue-distinctiveness-overrides-category-in-determining-performance-in-multiple-object-tracking
#14
Mengdan Sun, Xuemin Zhang, Lingxia Fan, Luming Hu
The visual distinctiveness between targets and distractors can significantly facilitate performance in multiple object tracking (MOT), in which color is a feature that has been commonly used. However, the processing of color can be more than "visual." Color is continuous in chromaticity, while it is commonly grouped into discrete categories (e.g., red, green). Evidence from color perception suggested that color categories may have a unique role in visual tasks independent of its chromatic appearance. Previous MOT studies have not examined the effect of chromatic and categorical distinctiveness on tracking separately...
December 13, 2017: Attention, Perception & Psychophysics
https://www.readbyqxmd.com/read/29238901/tower-of-babel-problem-in-telehealth-addressing-the-health-information-exchange-needs-of-the-north-carolina-statewide-telepsychiatry-program-nc-step
#15
Sy Atezaz Saeed
Telepsychiatry is a viable option for providing psychiatric care to those who are currently underserved or who lack access to services. While the current technology is adequate for most uses, and continues to advance, there remain barriers to its widespread utilization. One such barrier when working with different healthcare systems is that they utilize different electronic medical record systems (EMRs). This paper describes the experience of the North Carolina Statewide Telepsychiatry Program (NC-STeP) with this problem and how the program successfully resolved it by establishing a web portal that connects participating hospital emergency departments and remote psychiatric providers to share secure electronic health information regarding patient encounters across different EMRs...
December 14, 2017: Psychiatric Quarterly
https://www.readbyqxmd.com/read/29238858/spatial-organization-of-chromosome-territories-in-the-interphase-nucleus-of-trisomy-21-cells
#16
Stephan Kemeny, Christophe Tatout, Gaelle Salaun, Céline Pebrel-Richard, Carole Goumy, Natasha Ollier, Eugenie Maurin, Bruno Pereira, Philippe Vago, Laetitia Gouas
In the interphase cell nucleus, chromosomes adopt a conserved and non-random arrangement in subnuclear domains called chromosome territories (CTs). Whereas chromosome translocation can affect CT organization in tumor cell nuclei, little is known about how aneuploidies can impact CT organization. Here, we performed 3D-FISH on control and trisomic 21 nuclei to track the patterning of chromosome territories, focusing on the radial distribution of trisomic HSA21 as well as 11 disomic chromosomes. We have established an experimental design based on cultured chorionic villus cells which keep their original mesenchymal features including a characteristic ellipsoid nuclear morphology and a radial CT distribution that correlates with chromosome size...
December 14, 2017: Chromosoma
https://www.readbyqxmd.com/read/29238566/water-level-affects-availability-of-optimal-feeding-habitats-for-threatened-migratory-waterbirds
#17
Yaara Aharon-Rotman, John McEvoy, Zheng Zhaoju, Hui Yu, Xin Wang, Yali Si, Zhenggang Xu, Zeng Yuan, Wooseog Jeong, Lei Cao, Anthony D Fox
Extensive ephemeral wetlands at Poyang Lake, created by dramatic seasonal changes in water level, constitute the main wintering site for migratory Anatidae in China. Reductions in wetland area during the last 15 years have led to proposals to build a Poyang Dam to retain high winter water levels within the lake. Changing the natural hydrological system will affect waterbirds dependent on water level changes for food availability and accessibility. We tracked two goose species with different feeding behaviors (greater white-fronted geese Anser albifrons [grazing species] and swan geese Anser cygnoides [tuber-feeding species]) during two winters with contrasting water levels (continuous recession in 2015; sustained high water in 2016, similar to those predicted post-Poyang Dam), investigating the effects of water level change on their habitat selection based on vegetation and elevation...
December 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/29238559/evolution-to-environmental-contamination-ablates-the-circadian-clock-of-an-aquatic-sentinel-species
#18
Kayla D Coldsnow, Rick A Relyea, Jennifer M Hurley
Environmental contamination is a common cause of rapid evolution. Recent work has shown that Daphnia pulex, an important freshwater species, can rapidly evolve increased tolerance to a common contaminant, sodium chloride (NaCl) road salt. While such rapid evolution can benefit organisms, allowing them to adapt to new environmental conditions, it can also be associated with unforeseen tradeoffs. Given that exposure to environmental contaminants can cause circadian disruption, we investigated whether the circadian clock was affected by evolving a tolerance to high levels of road salt...
December 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/29238552/taking-movement-data-to-new-depths-inferring-prey-availability-and-patch-profitability-from-seabird-foraging-behavior
#19
Marianna Chimienti, Thomas Cornulier, Ellie Owen, Mark Bolton, Ian M Davies, Justin M J Travis, Beth E Scott
Detailed information acquired using tracking technology has the potential to provide accurate pictures of the types of movements and behaviors performed by animals. To date, such data have not been widely exploited to provide inferred information about the foraging habitat. We collected data using multiple sensors (GPS, time depth recorders, and accelerometers) from two species of diving seabirds, razorbills (Alca torda, N = 5, from Fair Isle, UK) and common guillemots (Uria aalge, N = 2 from Fair Isle and N = 2 from Colonsay, UK)...
December 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/29238452/letter-to-the-editor-licensure-portability-for-occupational-audiologists-is-essential
#20
George R Cook
Occupational audiologists have a crisis in their profession and need advocates. These audiologists are primarily responsible for industrial hearing conservation programs and their compliance with multiple regulations, such as Occupational Safety and Health Administration (OSHA), Mine Safety and Health Administration (MSHA) and the Federal Railroad Administration. Occupational hearing programs, for the most part, are multi-state programs as companies and corporations are national organizations. Also, companies may contract services across state lines as local services may not be desired or available...
2017: International Journal of Telerehabilitation
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