keyword
https://read.qxmd.com/read/36938140/postoperative-outcomes-using-lichtenstein-open-hernioplasty-versus-nyhus-preperitoneal-hernioplasty-in-inguinal-hernia-a-comparative-analysis-with-1-year-follow-up
#21
JOURNAL ARTICLE
Luis F Cabrera-Vargas, Andrés Mendoza-Zuchini, Brandon S Aparicio, Mauricio Pedraza, Walter A Sajona-Leguia, Jhoan S R Arias, Ivan D Lozada-Martinez, Yelson A Picón-Jaimes, Alexis R Narvaez-Rojas
BACKGROUND AND AIM: Inguinal hernia is the most common defect of the abdominal wall in 75% and their treatment consists of surgical repair. The technique of choice is laparoscopic because of its overall benefits. However, when this is not available, open approaches may be a viable option. Currently, the most commonly used open techniques are Lichtenstein and Nyhus. However, there are few medium- or long-term studies that have compared outcomes between these two techniques. METHODS: This is a retrospective comparative study that included patients undergoing open inguinal hernia correction with mesh, using Lichtenstein open hernioplasty versus Nyhus preperitoneal hernioplasty, in two tertiary referral centers in Bogota, Colombia, during a period of 2 years...
March 2023: Health Science Reports
https://read.qxmd.com/read/36538409/safety-and-efficacy-of-plasma-transfusion-from-exercise-trained-donors-in-patients-with-early-alzheimer-s-disease-protocol-for-the-explas-study
#22
JOURNAL ARTICLE
Atefe R Tari, Helene Haugen Berg, Vibeke Videm, Geir Bråthen, Linda R White, Ragnhild Nyhus Røsbjørgen, Katja Scheffler, Havard Dalen, Espen Holte, Asta K Haberg, Geir Selbaek, Stian Lydersen, Emrah Duezel, Sverre Bergh, Kjell Rune Logan-Halvorsrud, Sigrid Botne Sando, Ulrik Wisløff
INTRODUCTION: Given that exercise training reduces the risk of developing Alzheimer's disease (AD), induces changes in the blood composition and has widespread systemic benefits, it is reasonable to hypothesise that exercised plasma (ExPlas) may have rejuvenative properties. The main objective is to test safety and tolerability of transfusing ExPlas from young, healthy, fit adults to patients with mild cognitive impairment (MCI) or early AD. The study is a pilot for a future efficacy study...
September 6, 2022: BMJ Open
https://read.qxmd.com/read/36484214/everolimus-eluting-bioresorbable-scaffold-versus-everolimus-eluting-metallic-stent-in-primary-percutaneous-coronary-intervention-of-st-segment-elevation-myocardial-infarction-a-randomized-controlled-trial
#23
RANDOMIZED CONTROLLED TRIAL
Erlend Eriksen, Omeed Neghabat, Sahrai Saeed, Jon Herstad, Jan Erik Nordrehaug, Vegard Tuseth, Niels Ramsing Holm, Emil Nielsen Holck, Martin Sejr-Hansen, Camilla Fox Maule, Trine Ørhøj Barkholt, Lene Nyhus Andreasen, Evald Høj Christiansen, Øyvind Bleie
BACKGROUND: Primary percutaneous coronary intervention with implantation of a metallic drug-eluting stent (DES) is the standard treatment for patients presenting with ST-elevation myocardial infarction (STEMI). Implantation of a bioresorbable scaffold (BRS) during STEMI represents a novel strategy without intravascular metal. OBJECTIVE: The aim of the study was to investigate 12-month healing response in an STEMI population after implantation of either the Absorb BRS or Xience DES (Abbott Vascular, USA)...
January 1, 2023: Coronary Artery Disease
https://read.qxmd.com/read/36435864/tak1-inhibitors-did-not-reduce-disease-burden-in-a-v%C3%AE%C2%BA-myc-model-of-multiple-myeloma
#24
JOURNAL ARTICLE
Erling Håland, Ingrid Nyhus Moen, Esten N Vandsemb, Kristian K Starheim
OBJECTIVE: Multiple myeloma is a haematological malignancy characterized by proliferation of monoclonal plasma cells in the bone marrow. Development of resistance and minimal residual disease remain challenging in the treatment of multiple myeloma. Transforming growth factor-β activated kinase 1 (TAK1) has recently gained attention as a potential drug target in multiple myeloma. This study aimed at determining the in vivo effects of TAK1-inhibitors in a Vκ*MYC multiple myeloma mouse model...
November 26, 2022: BMC Research Notes
https://read.qxmd.com/read/36426831/-not-available
#25
JOURNAL ARTICLE
Uffe Mark Lauridsen, Joyce Dominique J Horsmans Schultz, Christa Haugaard Nyhus, Jesper Roed Sørensen
Injection augmentation of the vocal cords is a recognized treatment modality in patients with glottal closure deficiency caused by paresis or paralysis of the vocal cord. The treatment can improve voice quality and also quality of life. It is preferable to minimize waiting time for the procedure for patients with lung cancer and mediastinal involvement, because the one-year mortality is above 40%, as argued in this review.
November 21, 2022: Ugeskrift for Laeger
https://read.qxmd.com/read/36074391/inguinal-hernia-in-southern-brazil-challenges-in-follow-up-and-recurrence-rates
#26
JOURNAL ARTICLE
Rodrigo Piltcher-DA-Silva, Debora Oliveira Hütten, Artur Gehres Trapp, Pedro San Martin Soares, Tiago Lima Castro, Simoni Bohnenberger, Eduardo Castelli Kroth, Jorge Armando Reyes Pinto, Caroline Grehs, Danielle Cristina Tomasi, Leandro Totti Cavazzola
INTRODUCTION: recurrence rates for primary hernia repair range from 0.5 to 15 percent depending upon the hernia site, type of repair, and clinical circumstances. Many risk factors are known and they must be considered before the procedure. In developing countries, follow up and maintenance of databases are critical to understand the real numbers. METHODS: a retrospective cohort study analyzed adult patients who have undergone inguinal hernia repair at Hospital de Clínicas de Porto Alegre, a tertiary care government public hospital, between 2013 and 2015...
2022: Revista do Colégio Brasileiro de Cirurgiões
https://read.qxmd.com/read/35995375/theta-oscillations-support-active-exploration-in-human-spatial-navigation
#27
JOURNAL ARTICLE
Elizabeth R Chrastil, Caroline Rice, Mathias Goncalves, Kylie N Moore, Syanah C Wynn, Chantal E Stern, Erika Nyhus
Active navigation seems to yield better spatial knowledge than passive navigation, but it is unclear how active decision-making influences learning and memory. Here, we examined the contributions of theta oscillations to memory-related exploration while testing theories about how they contribute to active learning. Using electroencephalography (EEG), we tested individuals on a maze-learning task in which they made discrete decisions about where to explore at each choice point in the maze. Half the participants were free to make active decisions at each choice point, and the other half passively explored by selecting a marked choice (matched to active exploration) at each intersection...
August 19, 2022: NeuroImage
https://read.qxmd.com/read/35880860/a-scalable-and-modular-automated-pipeline-for-stitching-of-large-electron-microscopy-datasets
#28
JOURNAL ARTICLE
Gayathri Mahalingam, Russel Torres, Daniel Kapner, Eric T Trautman, Tim Fliss, Shamishtaa Seshamani, Eric Perlman, Rob Young, Samuel Kinn, JoAnn Buchanan, Marc M Takeno, Wenjing Yin, Daniel J Bumbarger, Ryder P Gwinn, Julie Nyhus, Ed Lein, Steven J Smith, R Clay Reid, Khaled A Khairy, Stephan Saalfeld, Forrest Collman, Nuno Macarico da Costa
Serial-section electronmicroscopy (ssEM) is themethod of choice for studyingmacroscopic biological samples at extremely high resolution in three dimensions. In the nervous system, nanometer-scale images are necessary to reconstruct dense neural wiring diagrams in the brain, so called connectomes. In order to use this data, consisting of up to 108 individual EM images, it must be assembled into a volume, requiring seamless 2D stitching from each physical section followed by 3D alignment of the stitched sections...
July 26, 2022: ELife
https://read.qxmd.com/read/35774003/development-of-nurse-led-videoconference-delivered-cognitive-behavioural-therapy-for-domestic-violence-feasibility-and-acceptability
#29
JOURNAL ARTICLE
Merete Berg Nesset, Christian Lauvrud, Anne Meisingset, Eskil Nyhus, Tom Palmstierna, Mariela Loreto Lara-Cabrera
AIMS: Because of the COVID-19 lockdown, an internet-based adaption of a nurse-led cognitive behavioural group therapy (CGBT) was provided for perpetrators of domestic violence. The aim of this study was to describe the development of the therapy, examine the initial feasibility and impact on patient satisfaction of the programme and evaluate the associated patient-reported experiences. DESIGN: Programme development as well as testing its feasibility and acceptability using cross-sectional survey data...
April 2023: Journal of Advanced Nursing
https://read.qxmd.com/read/35385224/vocal-markers-of-autism-assessing-the-generalizability-of-machine-learning-models
#30
JOURNAL ARTICLE
Astrid Rybner, Emil Trenckner Jessen, Marie Damsgaard Mortensen, Stine Nyhus Larsen, Ruth Grossman, Niels Bilenberg, Cathriona Cantio, Jens Richardt Møllegaard Jepsen, Ethan Weed, Arndis Simonsen, Riccardo Fusaroli
Machine learning (ML) approaches show increasing promise in their ability to identify vocal markers of autism. Nonetheless, it is unclear to what extent such markers generalize to new speech samples collected, for example, using a different speech task or in a different language. In this paper, we systematically assess the generalizability of ML findings across a variety of contexts. We train promising published ML models of vocal markers of autism on novel cross-linguistic datasets following a rigorous pipeline to minimize overfitting, including cross-validated training and ensemble models...
June 2022: Autism Research: Official Journal of the International Society for Autism Research
https://read.qxmd.com/read/35347367/the-impact-of-levator-ani-muscle-trauma-and-contraction-on-recurrence-after-prolapse-surgery
#31
JOURNAL ARTICLE
M Ø Nyhus, S Mathew, K Å Salvesen, I Volløyhaug
INTRODUCTION AND HYPOTHESIS: The objective was to explore the impact of levator ani muscle (LAM) trauma and pelvic floor contraction on symptoms and anatomy after pelvic organ prolapse (POP) surgery. METHODS: Prospective study including 200 women with symptomatic POP ≥ grade 2 examined 3 months prior to and 6 months after surgery. Prolapse in each compartment was graded using the Pelvic Organ Prolapse Quantification (POP-Q) system, and women answered yes/no to a question about bulge sensation...
March 28, 2022: International Urogynecology Journal
https://read.qxmd.com/read/35120187/progression-in-training-volume-and-perceived-psychological-and-physiological-training-distress-in-norwegian-student-athletes-a-cross-sectional-study
#32
JOURNAL ARTICLE
Cathrine Nyhus Hagum, Espen Tønnessen, Shaher A I Shalfawi
This cross-sectional study examined self-reported weekly training volume and perceived training distress in Norwegian student athletes according to gender, type of sport, school program, and school year. The Norwegian version of the Multicomponent Training Distress Scale (MTDS-N) was completed by 608 student athletes (M age = 17.29 ± .94). Univariate and multivariate techniques were used in data analyses. Results revealed significant differences in weekly training volume between sport types. No significant differences in weekly training volume were found for gender, school year, or school program...
2022: PloS One
https://read.qxmd.com/read/34992294/author-correction-human-neocortical-expansion-involves-glutamatergic-neuron-diversification
#33
Jim Berg, Staci A Sorensen, Jonathan T Ting, Jeremy A Miller, Thomas Chartrand, Anatoly Buchin, Trygve E Bakken, Agata Budzillo, Nick Dee, Song-Lin Ding, Nathan W Gouwens, Rebecca D Hodge, Brian Kalmbach, Changkyu Lee, Brian R Lee, Lauren Alfiler, Katherine Baker, Eliza Barkan, Allison Beller, Kyla Berry, Darren Bertagnolli, Kris Bickley, Jasmine Bomben, Thomas Braun, Krissy Brouner, Tamara Casper, Peter Chong, Kirsten Crichton, Rachel Dalley, Rebecca de Frates, Tsega Desta, Samuel Dingman Lee, Florence D'Orazi, Nadezhda Dotson, Tom Egdorf, Rachel Enstrom, Colin Farrell, David Feng, Olivia Fong, Szabina Furdan, Anna A Galakhova, Clare Gamlin, Amanda Gary, Alexandra Glandon, Jeff Goldy, Melissa Gorham, Natalia A Goriounova, Sergey Gratiy, Lucas Graybuck, Hong Gu, Kristen Hadley, Nathan Hansen, Tim S Heistek, Alex M Henry, Djai B Heyer, DiJon Hill, Chris Hill, Madie Hupp, Tim Jarsky, Sara Kebede, Lisa Keene, Lisa Kim, Mean-Hwan Kim, Matthew Kroll, Caitlin Latimer, Boaz P Levi, Katherine E Link, Matthew Mallory, Rusty Mann, Desiree Marshall, Michelle Maxwell, Medea McGraw, Delissa McMillen, Erica Melief, Eline J Mertens, Leona Mezei, Norbert Mihut, Stephanie Mok, Gabor Molnar, Alice Mukora, Lindsay Ng, Kiet Ngo, Philip R Nicovich, Julie Nyhus, Gaspar Olah, Aaron Oldre, Victoria Omstead, Attila Ozsvar, Daniel Park, Hanchuan Peng, Trangthanh Pham, Christina A Pom, Lydia Potekhina, Ramkumar Rajanbabu, Shea Ransford, David Reid, Christine Rimorin, Augustin Ruiz, David Sandman, Josef Sulc, Susan M Sunkin, Aaron Szafer, Viktor Szemenyei, Elliot R Thomsen, Michael Tieu, Amy Torkelson, Jessica Trinh, Herman Tung, Wayne Wakeman, Femke Waleboer, Katelyn Ward, René Wilbers, Grace Williams, Zizhen Yao, Jae-Geun Yoon, Costas Anastassiou, Anton Arkhipov, Pal Barzo, Amy Bernard, Charles Cobbs, Philip C de Witt Hamer, Richard G Ellenbogen, Luke Esposito, Manuel Ferreira, Ryder P Gwinn, Michael J Hawrylycz, Patrick R Hof, Sander Idema, Allan R Jones, C Dirk Keene, Andrew L Ko, Gabe J Murphy, Lydia Ng, Jeffrey G Ojemann, Anoop P Patel, John W Phillips, Daniel L Silbergeld, Kimberly Smith, Bosiljka Tasic, Rafael Yuste, Idan Segev, Christiaan P J de Kock, Huibert D Mansvelder, Gabor Tamas, Hongkui Zeng, Christof Koch, Ed S Lein
No abstract text is available yet for this article.
January 6, 2022: Nature
https://read.qxmd.com/read/34888712/correction-to-comparison-of-laparoscopic-transabdominal-preperitoneal-hernioplasty-and-laparoscopic-iliopubic-tract-repair-for-nyhus-type-ii-hernia-in-women
#34
Sung Ryul Lee, Jin Young Park
No abstract text is available yet for this article.
February 2022: Surgical Endoscopy
https://read.qxmd.com/read/34676048/tak1-inhibitors-are-cytotoxic-for-multiple-myeloma-cells-alone-and-in-combination-with-melphalan
#35
JOURNAL ARTICLE
Erling Håland, Ingrid Nyhus Moen, Elias Veidal, Hanne Hella, Kristine Misund, Tobias S Slørdahl, Kristian K Starheim
Multiple myeloma (MM) is an incurable cancer caused by malignant transformation of plasma cells. Transforming growth factor-β activated kinase 1 (MAP3K7, TAK1) is a major regulator of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) and mitogen-activated protein kinase (MAPK) signaling. Both NF-κB and MAPK control expression of genes with vital roles for drug resistance in MM. TAK1 is an attractive drug target as it switches these survival pathways to cell death. Our analysis showed that patients with high MAP3K7 expression in the tumor had shorter overall and progression free survival...
October 12, 2021: Oncotarget
https://read.qxmd.com/read/34616067/human-neocortical-expansion-involves-glutamatergic-neuron-diversification
#36
JOURNAL ARTICLE
Jim Berg, Staci A Sorensen, Jonathan T Ting, Jeremy A Miller, Thomas Chartrand, Anatoly Buchin, Trygve E Bakken, Agata Budzillo, Nick Dee, Song-Lin Ding, Nathan W Gouwens, Rebecca D Hodge, Brian Kalmbach, Changkyu Lee, Brian R Lee, Lauren Alfiler, Katherine Baker, Eliza Barkan, Allison Beller, Kyla Berry, Darren Bertagnolli, Kris Bickley, Jasmine Bomben, Thomas Braun, Krissy Brouner, Tamara Casper, Peter Chong, Kirsten Crichton, Rachel Dalley, Rebecca de Frates, Tsega Desta, Samuel Dingman Lee, Florence D'Orazi, Nadezhda Dotson, Tom Egdorf, Rachel Enstrom, Colin Farrell, David Feng, Olivia Fong, Szabina Furdan, Anna A Galakhova, Clare Gamlin, Amanda Gary, Alexandra Glandon, Jeff Goldy, Melissa Gorham, Natalia A Goriounova, Sergey Gratiy, Lucas Graybuck, Hong Gu, Kristen Hadley, Nathan Hansen, Tim S Heistek, Alex M Henry, Djai B Heyer, DiJon Hill, Chris Hill, Madie Hupp, Tim Jarsky, Sara Kebede, Lisa Keene, Lisa Kim, Mean-Hwan Kim, Matthew Kroll, Caitlin Latimer, Boaz P Levi, Katherine E Link, Matthew Mallory, Rusty Mann, Desiree Marshall, Michelle Maxwell, Medea McGraw, Delissa McMillen, Erica Melief, Eline J Mertens, Leona Mezei, Norbert Mihut, Stephanie Mok, Gabor Molnar, Alice Mukora, Lindsay Ng, Kiet Ngo, Philip R Nicovich, Julie Nyhus, Gaspar Olah, Aaron Oldre, Victoria Omstead, Attila Ozsvar, Daniel Park, Hanchuan Peng, Trangthanh Pham, Christina A Pom, Lydia Potekhina, Ramkumar Rajanbabu, Shea Ransford, David Reid, Christine Rimorin, Augustin Ruiz, David Sandman, Josef Sulc, Susan M Sunkin, Aaron Szafer, Viktor Szemenyei, Elliot R Thomsen, Michael Tieu, Amy Torkelson, Jessica Trinh, Herman Tung, Wayne Wakeman, Femke Waleboer, Katelyn Ward, René Wilbers, Grace Williams, Zizhen Yao, Jae-Geun Yoon, Costas Anastassiou, Anton Arkhipov, Pal Barzo, Amy Bernard, Charles Cobbs, Philip C de Witt Hamer, Richard G Ellenbogen, Luke Esposito, Manuel Ferreira, Ryder P Gwinn, Michael J Hawrylycz, Patrick R Hof, Sander Idema, Allan R Jones, C Dirk Keene, Andrew L Ko, Gabe J Murphy, Lydia Ng, Jeffrey G Ojemann, Anoop P Patel, John W Phillips, Daniel L Silbergeld, Kimberly Smith, Bosiljka Tasic, Rafael Yuste, Idan Segev, Christiaan P J de Kock, Huibert D Mansvelder, Gabor Tamas, Hongkui Zeng, Christof Koch, Ed S Lein
The neocortex is disproportionately expanded in human compared with mouse1,2 , both in its total volume relative to subcortical structures and in the proportion occupied by supragranular layers composed of neurons that selectively make connections within the neocortex and with other telencephalic structures. Single-cell transcriptomic analyses of human and mouse neocortex show an increased diversity of glutamatergic neuron types in supragranular layers in human neocortex and pronounced gradients as a function of cortical depth3 ...
October 2021: Nature
https://read.qxmd.com/read/34554958/appropriate-coding-and-billing-in-occupational-health
#37
JOURNAL ARTICLE
Julie E Nyhus
Occupational health medicine plays a critical role in prevention, recognition, and treatment of injuries and illnesses of workers. This article explores commonly billed occupational injuries and illnesses.
October 1, 2021: Nurse Practitioner
https://read.qxmd.com/read/34554090/letter-when-is-the-optimal-time-point-for-detecting-malapposition-in-coronary-bifurcation-trials
#38
JOURNAL ARTICLE
Emil Nielsen Holck, Lene Nyhus Andreasen
No abstract text is available yet for this article.
September 20, 2021: EuroIntervention
https://read.qxmd.com/read/34542701/comparison-of-laparoscopic-transabdominal-preperitoneal-hernioplasty-and-laparoscopic-iliopubic-tract-repair-for-nyhus-type-ii-hernia-in-women
#39
JOURNAL ARTICLE
Sung Ryul Lee, Jin Young Park
BACKGROUND: Indirect inguinal hernia with a dilated internal ring but an intact posterior inguinal wall is classified as Nyhus type II. Females have a higher incidence of indirect hernia than direct hernia. The purpose of this study was to evaluate the efficacy of laparoscopic iliopubic tract repair (IPTR) compared with laparoscopic transabdominal preperitoneal (TAPP) hernioplasty in treating women with Nyhus type II hernia. METHODS: This retrospective study included 318 women aged ≥ 20 years who were treated for Nyhus type II hernia from January 2013 to December 2018...
September 20, 2021: Surgical Endoscopy
https://read.qxmd.com/read/34525221/cellular-resolution-anatomical-and-molecular-atlases-for-prenatal-human-brains
#40
JOURNAL ARTICLE
Song-Lin Ding, Joshua J Royall, Phil Lesnar, Benjamin A C Facer, Kimberly A Smith, Yina Wei, Kristina Brouner, Rachel A Dalley, Nick Dee, Tim A Dolbeare, Amanda Ebbert, Ian A Glass, Nika H Keller, Felix Lee, Tracy A Lemon, Julie Nyhus, Julie Pendergraft, Robert Reid, Melaine Sarreal, Nadiya V Shapovalova, Aaron Szafer, John W Phillips, Susan M Sunkin, John G Hohmann, Allan R Jones, Michael J Hawrylycz, Patrick R Hof, Lydia Ng, Amy Bernard, Ed S Lein
Increasing interest in studies of prenatal human brain development, particularly using new single-cell genomics and anatomical technologies to create cell atlases, creates a strong need for accurate and detailed anatomical reference atlases. In this study, we present two cellular-resolution digital anatomical atlases for prenatal human brain at post-conceptional weeks (PCW) 15 and 21. Both atlases were annotated on sequential Nissl-stained sections covering brain-wide structures on the basis of combined analysis of cytoarchitecture, acetylcholinesterase staining and an extensive marker gene expression dataset...
September 15, 2021: Journal of Comparative Neurology
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