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https://www.readbyqxmd.com/read/28546964/application-of-the-initial-rate-method-in-anaerobic-digestion-of-kitchen-waste
#1
Lei Feng, Yuan Gao, Wei Kou, Xianming Lang, Yiwei Liu, Rundong Li, Meiling Yu, Lijie Shao, Xiaoming Wang
This article proposes a methane production approach through sequenced anaerobic digestion of kitchen waste, determines the hydrolysis constants and reaction orders at both low total solid (TS) concentrations and high TS concentrations using the initial rate method, and examines the population growth model and first-order hydrolysis model. The findings indicate that the first-order hydrolysis model better reflects the kinetic process of gas production. During the experiment, all the influential factors of anaerobic fermentation retained their optimal values...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28545390/mqaprank-improved-global-protein-model-quality-assessment-by-learning-to-rank
#2
Xiaoyang Jing, Qiwen Dong
BACKGROUND: Protein structure prediction has achieved a lot of progress during the last few decades and a greater number of models for a certain sequence can be predicted. Consequently, assessing the qualities of predicted protein models in perspective is one of the key components of successful protein structure prediction. Over the past years, a number of methods have been developed to address this issue, which could be roughly divided into three categories: single methods, quasi-single methods and clustering (or consensus) methods...
May 25, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/28543179/genetic-ancestry-and-prostate-cancer-susceptibility-snps-in-puerto-rican-and-african-american-men
#3
Margarita Irizarry-Ramírez, Rick A Kittles, Xuemei Wang, Jeannette Salgado-Montilla, Graciela M Nogueras-González, Ricardo Sánchez-Ortiz, Lourdes Guerrios, Keila Rivera, Ebony Shah, Ina Prokhorova, Pamela Roberson, Patricia Troncoso, Curtis A Pettaway
BACKGROUND: The Puerto Rican (PR) population is a racially admixed population that has a high prostate cancer (PCa) mortality rate. We hypothesized in this pilot study that West African Ancestry (WAA) was associated with PCa in this heterogeneous (PR) population. METHODS: A case/case and case/control study was performed. Controls, 207 African American (AA) and 133 PR were defined as men with no PCa, a serum PSA < 2.5 ng/mL and a negative rectal examination...
May 24, 2017: Prostate
https://www.readbyqxmd.com/read/28540124/relationship-of-the-sinus-anatomy-to-surface-landmarks-is-a-function-of-the-sinus-size-difference-between-the-right-and-left-side-anatomical-study-based-on-ct-angiography
#4
Roy S Hwang, Ryan C Turner, Walid Radwan, Rahul Singh, Brandon Lucke-Wold, Abdul Tarabishy, Sanjay Bhatia
BACKGROUND: Several cadaveric studies demonstrate reliable localization of the transverse sinus and the transverse sigmoid junction (TSJ). These studies use the line drawn from the inion to the posterior root of the zygoma (IZ) and the asterion, respectively. We investigated how the size difference between the right and left transverse sinuses (TS) and sigmoid sinuses (SS) affected the accuracy of their respective superficial landmarks, particularly with regards to where this relationship may result in unsafe and/or complicated surgical access...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28539716/prevention-mechanism-of-2-3-5-4-tetrahydroxy-stilbene-2-o-%C3%AE-d-glucoside-on-lipid-accumulation-in-steatosis-hepatic-l-02-cell
#5
Pei Lin, Jian-Mei Lu, Yan-Fang Wang, Wen Gu, Rong-Hua Zhao, Jie Yu
AIM: 2,3,5,4'-Tetrahydroxy-stilbene-2-O-β-d-glucoside (TSG), a natural stilbene, shows great activities in hepatic lipid regulation, especially for hepatic triglyceride lowering. However, information about its mechanisms on biosynthesis and degradation of triglyceride is still limited. This research pays close attention to clarify the mechanism of TSG on prevention of hepatic lipid accumulation. MATERIALS AND METHODS: TSG was given to steatosis hepatocyte L-02 cell induced by fat emulsion incubation...
April 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/28538779/sweat-test-and-cystic-fibrosis-overview-of-test-performance-at-public-and-private-centers-in-the-state-of-s%C3%A3-o-paulo-brazil
#6
Maria Fátima Servidoni, Carla Cristina Souza Gomez, Fernando Augusto Lima Marson, Adyléia Aparecida Dalbo Contrera Toro, Maria Ângela Gonçalves de Oliveira Ribeiro, José Dirceu Ribeiro, Antônio Fernando Ribeiro
Objective: The sweat test (ST) measures chloride levels in sweat and is considered the gold standard for the diagnosis of cystic fibrosis (CF). However, the reliability of a ST depends on their being performed by experienced technicians and in accordance with strict guidelines. Our aim was to evaluate how sweat stimulation, sweat collection, and chloride measurement are performed at 14 centers (9 public centers and 5 private centers) that routinely perform STs in the state of São Paulo, which has the highest frequency of CF in Brazil...
March 2017: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/28538067/review-of-a-multi-modal-parcellation-of-human-cerebral-cortex-by-glasser-m-coalson-ts-robinson-ec-hacker-cd-harwell-j-yacoub-e-ugurbil-k-andersson-j-beckmann-cf-jenkinson-m-smith-sm-van-essen-dc-in-nature-536-171-181-2016
#7
https://www.readbyqxmd.com/read/28536913/histopathological-changes-in-zebrafish-embryos-exposed-to-dlpcbs-extract-from-zhanjiang-coastal-sediment
#8
Yunpeng Yu, Fanghong Nie, Anthony Hay, Hongying Lin, Yi Ma, Xianghong Ju, Dongliang Gong, Jinjun Chen, Ravi Gooneratne
Dioxin-like polychlorinated biphenyls (DLPCBs) are ubiquitous persistent pollutants that cause adverse effects in many environmental organisms. DLPCBs in marine sediments can be absorbed by benthic organisms, bioaccumulate, and biomagnify through the food chain and threaten animal and human health. There are no reports of DLPCBs concentrations in the Zhanjiang Gulf seabed. This study was designed to investigate the concentration of DLPCBs in the Zhanjiang coastal sediment and histopathological changes in zebrafish (Diano rerio) embryos exposed to environmentally relevant concentrations of DLPCBs...
June 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28536016/production-and-characterization-of-a-new-biodegradable-fenugreek-seed-gum-based-active-nanocomposite-film-reinforced-with-nanoclays
#9
Saliha Memiş, Fatih Tornuk, Fatih Bozkurt, M Zeki Durak
In the present work, fenugreek seed gum (FSG)/clay nanocomposite films were prepared with nanoclays (Na(+) montmorillonite [MMT], halloysite [HNT] and Nanomer® I.44 P [NM]) at different amounts (0, 2.5, 5.0 and 7.5g clay/100g FSG) by solution casting method and characterized. Increasing amount of nanoclay significantly (P<0.05) improved oxygen barrier and thermal properties of the biodegradable films. Agar diffusion tests revealed that FSG based nanocomposite films exhibited strong antimicrobial properties against foodborne pathogens namely Listeria monocytogenes, Escherichia coli O157:H7, Staphylococcus aureus and Bacillus cereus independently of clay type and concentration...
May 20, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28534244/proposal-of-a-simple-optical-coherence-tomography-based-scoring-system-for-progression-of-age-related-macular-degeneration
#10
Jianqin Lei, Siva Balasubramanian, Nizar Saleh Abdelfattah, Muneeswar G Nittala, SriniVas R Sadda
PURPOSE: To develop a simple, clinically practical, optical coherence tomography (OCT)-based scoring system for early age-related macular degeneration (AMD) to prognosticate risk for progression to late AMD. METHODS: We retrospectively reviewed OCT images (512 × 128 macular cube, Cirrus) from 138 patients diagnosed of early AMD in at least one eye and follow-up of at least 12 months. For patients with early AMD in both eyes, only the right eye was chosen as the study eye for longitudinal assessment...
May 22, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28533178/mucin-and-carbohydrate-stimulated-adhesion-and-subproteome-changes-of-the-probiotic-bacterium-lactobacillus-acidophilus-ncfm
#11
Hasan Ufuk Celebioglu, Sita Vaag Olesen, Kennie Prehn, Sampo J Lahtinen, Susanne Brix, Maher Abou Hachem, Birte Svensson
Adhesion to intestinal mucosa is a crucial property for probiotic bacteria. Adhesion is thought to increase host-bacterial interactions, thus potentially enabling health benefits to the host. Molecular events connected with adhesion and surface proteome changes were investigated for the probiotic Lactobacillus acidophilus NCFM cultured with established or emerging prebiotic carbohydrates as carbon source and in the presence of mucin, the glycoprotein of the epithelial mucus layer. Variation in adhesion to HT29-cells and mucin was associated with carbon source and mucin-induced subproteome abundancy differences...
May 19, 2017: Journal of Proteomics
https://www.readbyqxmd.com/read/28532097/influence-of-telopeptides-on-the-structural-and-physical-properties-of-polymeric-and-monomeric-acid-soluble-type-i-collagen
#12
Róisín Holmes, Steve Kirk, Giuseppe Tronci, Xuebin Yang, David Wood
Currently two factors hinder the use of collagen as building block of regenerative devices: the limited mechanical strength in aqueous environment, and potential antigenicity. Polymeric collagen is naturally found in the cross-linked state and is mechanically tougher than the monomeric, acid-soluble collagen ex vivo. The antigenicity of collagen, on the other hand, is mainly ascribed to inter-species variations in amino acid sequences of the non-helical terminal telopeptides. These telopeptides can be removed through enzymatic treatment to produce atelocollagen, although the effect of this cleavage on triple helix organization, amino acidic composition and thermal properties is often disregarded...
August 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28530813/enhanced-sampling-of-phase-transitions-in-coarse-grained-lipid-bilayers
#13
David N Stelter, Tom Keyes
Freezing and melting of dipalmitoylphosphatidylcholine (DPPC) bilayers are simulated in both the explicit (Wet) and implicit solvent (Dry) coarse-grained MARTINI force fields with enhanced sampling, via the isobaric, molecular dynamics version of the generalized replica exchange method (gREM). Phase transitions are described with the entropic viewpoint, based upon the statistical temperature as a function of enthalpy, TS(H) = 1/(dS(H)/dH), where S is the configurational entropy. Bilayer thickness, area per lipid, and the second-rank order parameter (P2) are calculated vs temperature in the transition range...
May 22, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28528178/expanding-biological-activities-of-ts19-frag-ii-toxin-insights-into-il-17-production
#14
Felipe Augusto Cerni, Manuela Berto Pucca, Karina Furlani Zoccal, Fabiani Gai Frantz, Lucia Helena Faccioli, Eliane Candiani Arantes
Tityus serrulatus (Ts) venom is composed of a mixture of toxins presenting diverse biological functions. However, although this venom has been studied over the past three decades, omics analysis revealed that most of its toxins are not identified or their biological activities are unknown. Ts19 Frag-II is included is this group, which function is still uncertain. This study aimed to expand the biological activities of Ts19 Frag-II through in vivo investigation. Our results demonstrates that mice challenged with Ts19 Frag-II presented biochemical alterations, increasing serum levels of urea, ALT and β-globulin, besides decreasing γ-globulins...
May 17, 2017: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/28527679/salivary-steroid-response-and-competitive-anxiety-in-elite-basketball-players-effect-of-opponent-level
#15
Ademir F S Arruda, Marcelo S Aoki, Ana Carolina Paludo, Alexandre Moreira
This study examined the effect of playing matches against different opponent teams (hard match; HM, medium match; MM, and easy match; EM) on pre-match testosterone concentration (T), pre-to-post match cortisol (C) concentration, and pre-competitive anxiety (CSAI-2 questionnaire) in 20 elite male basketball players. One training session (TS) was also assessed (control condition). Saliva steroids were determined by ELISA. The pre-T concentration was significantly lower for the TS (163±54pmolL(-1)), compared to the three official matches (EM: 208±82pmolL(-1), MM: 213±57pmolL(-1), and HM: 218±37pmolL(-1)) (p<0...
May 17, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28526731/validated-bayesian-differentiation-of-causative-and-passenger-mutations
#16
Frederick R Cross, Michal Breker, Kristi Lieberman
In many contexts, the problem arises of determining which of many candidate mutations is the most likely to be causative for some phenotype. It is desirable to have a way to evaluate this probability that relies as little as possible on previous knowledge, to avoid bias against discovering new genes or functions. We are isolating mutants with blocked cell cycle progression in Chlamydomonas, and determining mutant genome sequences. Due to the intensity of UV mutagenesis required for efficient mutant collection, the mutants contain multiple mutations altering coding sequence...
May 19, 2017: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/28525990/transversions-have-larger-regulatory-effects-than-transitions
#17
Cong Guo, Ian C McDowell, Michael Nodzenski, Denise M Scholtens, Andrew S Allen, William L Lowe, Timothy E Reddy
BACKGROUND: Transversions (Tv's) are more likely to alter the amino acid sequence of proteins than transitions (Ts's), and local deviations in the Ts:Tv ratio are indicative of evolutionary selection on genes. Whether the two different types of mutations have different effects in non-protein-coding sequences remains unknown. Genetic variants primarily impact gene expression by disrupting the binding of transcription factors (TFs) and other DNA-binding proteins. Because Tv's cause larger changes in the shape of a DNA backbone, we hypothesized that Tv's would have larger impacts on TF binding and gene expression...
May 19, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28524707/asthma-specific-cognitions-self-focused-attention-and-fear-of-negative-evaluation-in-adolescents-and-young-adults-diagnosed-with-childhood-onset-asthma
#18
Ashley N Junghans-Rutelonis, Alayna P Tackett, Kristina I Suorsa, John M Chaney, Larry L Mullins
The present study examined the impact of asthma-specific thought intrusion (TI) and thought suppression (TS) on two cognitive-affective variables (self-focused attention and fear of negative evaluation) among adolescents and young adults (AYAs) diagnosed with childhood-onset asthma. Participants were 290 AYAs who completed assessment questionnaires and participated in a written exercise electronically. Asthma-TI and TS were reported by participants following participation in a writing assignment. Asthma-TI was associated with increased private, public, and social anxiety self-focused attention, and greater fear of negative evaluation...
May 19, 2017: Psychology, Health & Medicine
https://www.readbyqxmd.com/read/28523940/delay-in-estrogen-commencement-is-associated-with-lower-bone-mineral-density-in-turner-syndrome
#19
H H Nguyen, P Wong, B J Strauss, G Jones, P R Ebeling, F Milat, A Vincent
OBJECTIVE: Turner syndrome (TS) is associated with hypogonadism, osteoporosis and fractures. We investigated the prevalence and risk factors for low bone density and fractures in a TS cohort. METHODS: We included 76 TS patients (median age 28.5 years) attending a tertiary hospital between 1998 and 2015 who underwent dual-energy X-ray absorptiometry. Spine and femoral neck (FN) areal bone mineral density (aBMD) were compared with those of a control group. To adjust for smaller bone size, bone mineral apparent density (BMAD) was calculated...
May 19, 2017: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/28523481/mild-depression-in-low-back-pain-the-interaction-of-thought-suppression-and-stress-plays-a-role-especially-in-female-patients
#20
Konietzny Kerstin, Chehadi Omar, Streitlein-Böhme Irmgard, Rusche Herbert, Willburger Roland, Hasenbring Monika Ilona
PURPOSE: Mild depression has been shown as a precursor and as a consequence of low back pain, even in early phases of acute or subacute pain. Chronic daily life stress as well as dysfunctional pain-related cognitions such as thought suppression (TS) seem to play a role in the pain-depression cycle; however, the mechanisms of these associations are less understood. Experimentally induced TS, conceived as the attempt to directly suppress sensations such as pain, has been shown to paradoxically cause a delayed and non-volitional return of the suppressed thoughts and sensations and to increase affective distress...
May 18, 2017: International Journal of Behavioral Medicine
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