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https://www.readbyqxmd.com/read/28106624/intraoperative-electrocochleography-a-window-into-endolymphatic-hydrops-in-a-patient-with-an-endolymphatic-sac-tumor
#1
William J Riggs, Dominic J Catalano, Michael S Harris, Oliver F Adunka, Aaron C Moberly
OBJECTIVES: Intraoperative electrocochleography (ECochG) provides valuable information regarding inner ear function during surgical procedures. Here, we report findings from ECochG collected at three time intervals during the management of a patient with symptoms of inner ear hydrops. PATIENTS: A 38-year-old man with an endolymphatic sac tumor who demonstrated classic Ménière's symptoms. INTERVENTIONS: Endolymphatic shunt, tumor biopsy, and definitive resection of an endolymphatic sac tumor...
January 18, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28079865/differences-in-mortality-characteristics-in-neonates-with-down-s-syndrome
#2
C L Cua, U Haque, S Santoro, L Nicholson, C H Backes
OBJECTIVE: Neonates with Down's syndrome (nDS) may have multiple medical issues that place them at increased risk for mortality during the newborn period. Goal of this study was to determine if there are differences in baseline characteristics, medical complications or procedures performed during hospitalization between nDS who survived versus those who died during initial hospitalization. STUDY DESIGN: Data from 2000 to 2014 were reviewed using the Pediatric Health Information Systems (PHIS) database on all DS patients admitted to the hospital <30 days postnatal life...
January 12, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28076990/outcomes-in-the-absence-of-the-ductus-venosus-diagnosed-in-the-first-trimester
#3
Hiroko Takita, Junichi Hasegawa, Tatsuya Arakaki, Shoko Hamada, Mayumi Tokunaka, Masamitsu Nakamura, Ryu Matsuoka, Akihiko Sekizawa
PURPOSE: To clarify the outcomes of the absence of the ductus venosus diagnosed in fetuses suspected to have a structural abnormality during a morphological assessment in the first trimester. METHODS: Infants in whom ultrasound fetal morphological assessments were attempted in the first trimester (11 to 13-6 weeks of gestation) and who were subsequently delivered between 2013 and 2015 at Showa University Hospital were enrolled. In cases in which the absence of the ductus venosus was diagnosed in the first trimester, the prognosis was assessed...
January 11, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28072657/assessment-of-cochlea-endolymphatic-hydrops-using-3-d-flair-and-3-d-real-ir-sequence-in-guinea-pigs-via-3t-mri-after-intratympanic-gadolinium-a-histopathological-comparison
#4
Feng Wang, Huiying Lyu, Menglong Zhao, Yan Sha, Fang Zhang, Yushu Cheng, Wenhu Huang, Wenlin Tang, Youzhou Xie, Ping Lu
OBJECTIVE: We assessed whether the three-dimensional fluid-attenuated inversion-recovery (3-D FLAIR) and three-dimensional inversion-recovery with real reconstruction (3-D real IR) sequences can be used to detect cochlea endolymphatic hydrops (EHs) in guinea pigs using 3 Tesla magnetic resonance imaging (3T MRI). The results of 3-D real IR imaging were compared with histopathological outcomes. MATERIALS AND METHODS: Fourteen healthy men and women albino guinea pigs were used in this study...
January 9, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28064267/chemical-pleurodesis-with-oxytetracycline-in-congenital-chylothorax
#5
Alpana Utture, Vinayak Kodur, Jayashree Mondkar
BACKGROUND: Congenital chylothorax is an accumulation of chyle in the pleural space that may present in neonatal period with respiratory distress. CASE CHARACTERISTICS: A 34-week preterm who presented with massive congenital chylothorax complicated with hydrops fetalis. OUTCOME: The neonate was treated successfully by pleurodesis with Oxytetracycline. MESSAGE: Pleurodesis with oxytetracycline seems to be effective in treatment of congenital chylothorax...
December 15, 2016: Indian Pediatrics
https://www.readbyqxmd.com/read/28057638/an-international-registry-of-survivors-with-hb-bart-s-hydrops-fetalis-syndrome
#6
Duantida Songdej, Christian Babbs, Douglas R Higgs
Hb Bart's Hydrops Fetalis Syndrome (BHFS) resulting from α(0)-thalassemia is considered a universally fatal disorder. However, over the last three decades improvements in intrauterine interventions and perinatal intensive care have resulted in increasing numbers of BHFS survivors. We have initiated an international registry containing information on 69 patients, of which 31 are previously unpublished. In this perspective we analyze the available clinical information to document the natural history of BHFS...
January 5, 2017: Blood
https://www.readbyqxmd.com/read/28043830/fetal-primary-cardiac-tumors-during-perinatal-period
#7
REVIEW
Shi-Min Yuan
Fetal primary cardiac tumors are rare, but they may cause complications, which are sometimes life threatening, including arrhythmias, hydrops fetalis, ventricular outflow/inflow obstruction, cardiac failure, and even sudden death. Among fetal primary cardiac tumors, rhabdomyomas are most common, followed by teratomas, fibromas, hemangiomas, and myxomas. Everolimus, a mammalian target of rapamycin inhibitor, has been reported to be an effective drug to cause tumor remission in three neonates with multiple cardiac rhabdomyomas...
October 28, 2016: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/28040135/pallister-killian-syndrome-cytogenetics-and-molecular-investigations-of-mosaic-tetrasomy-12p-in-prenatal-chorionic-villus-and-in-amniocytes-strategy-of-prenatal-diagnosis
#8
Francesco Libotte, Domenico Bizzoco, Ivan Gabrielli, Alvaro Mesoraca, Pietro Cignini, Salvatore Giovanni Vitale, Ilaria Marilli, Ferdinando Antonio Gulino, Agnese Maria Chiara Rapisarda, Claudio Giorlandino
OBJECTIVE: Pallister-Killian syndrome (PKS) is a rare, sporadic genetic disorder caused by mosaic tetrasomy of the short arm of chromosome 12 (12p). Clinically, PKS is characterized by several systemic abnormalities, such as intellectual impairment, hearing loss, epilepsy, hypotonia, craniofacial dysmorphism, pigmentary skin anomalies, epilepsy, and a variety of congenital malformations. Prenatally, PKS can be suspected in the presence of ultrasound anomalies: diaphragmatic hernia, rhizomelic micromelia, hydrops fetalis, fetal overweight, ventriculomegaly in the central nervous system, congenital heart defects, or absent visualization of the stomach...
December 2016: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28033296/intratympanic-steroids-injection-is-effective-for-the-treatment-of-drop-attacks-with-m%C3%A3-ni%C3%A3-re-s-disease-and-delayed-endolymphatic-hydrops-a-retrospective-study
#9
Bo Liu, Yangming Leng, Renhong Zhou, Jingjing Liu, Dongdong Liu, Su-Lin Zhang, Wei-Jia Kong
Drop attack (DA) associated with Ménière's disease (MD) and delayed endolymphatic hydrops (DEH) is not common and may cause life-threatening clinical problems. The intratympanic dexamethasone (ITD) is one of primary treatments for MD or DEH. Our study investigated the effect of ITD on the DA associated with endolymphatic hydrops (EH).We retrospectively reviewed 10 patients with MD- and DEH-associated DA between January 2009 and December 2013 in Outpatient Department of Otolaryngology, Union Hospital, Wuhan, China...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28032647/fetal-hemodynamics-and-adverse-outcome-in-primary-school-aged-children-with-fetal-growth-restriction-a-prospective-longitudinal-study
#10
Noora Korkalainen, Juha Räsänen, Tuula Kaukola, Hanna Kallankari, Mikko Hallman, Kaarin Mäkikallio
INTRODUCTION: Fetal growth restriction is associated with short-term and long-term mortality and morbidity. We hypothesized that adverse outcome in children with fetal growth restriction at primary school age is associated with fetoplacental circulatory abnormalities. MATERIAL AND METHODS: Comprehensive ultrasonographic assessment of fetoplacental hemodynamics was performed in 72 growth-restricted fetuses prenatally, and short-term outcome data were collected. At the median age of 9 years, mortality and morbidity were determined using medical charts and questionnaires...
January 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/28030812/aflatoxin-b1-invokes-apoptosis-via-death-receptor-pathway-in-hepatocytes
#11
Muhammad Jameel Mughal, Xi Peng, Yi Zhou, Jing Fang
The fungal metabolites produced by Aspergillus flavus and Aspergillus parasiticus cause detrimental health effects on humans and animals. Particularly aflatoxin B1 (AFB1) is the most studied and a well-known global carcinogen, producing hepatotoxic, genotoxic and immunotoxic effects in multiple species. AFB1 is shown to provoke liver dysfunctioning by causing hepatocytes apoptosis and disturbing cellular enzymatic activities. In liver, AFB1 causes apoptosis via extrinsic mechanism because of high expression of death receptor pathway...
December 24, 2016: Oncotarget
https://www.readbyqxmd.com/read/28017456/diagnosis-of-endolymphatic-hydrops-by-means-of-3t-magnetic-resonance-imaging-after-intratympanic-administration-of-gadolinium
#12
M Tuñón Gómez, D R Lobo Duro, B Brea Álvarez, J R García-Berrocal
OBJECTIVE: To detect and graduate endolymphatic hydrops or endolymphatic space dilations in patients with suspected Meniere's disease or immune-mediated inner ear disease by magnetic resonance imaging. MATERIAL AND METHODS: A prospective study was performed including all the patients with clinical suspicion of Meniere's disease or immune-mediated inner ear disease treated at the Otolaryngology department during a one year period. In all cases, magnetic resonance imaging (MRI) was performed in a 3T scanner...
December 22, 2016: Radiología
https://www.readbyqxmd.com/read/28008591/mirror-syndrome-after-fetoscopic-laser-treatment-a-case-report
#13
Ana Maria Simões Brandão, Ana Patrícia Rodrigues Domingues, Etelvina Morais Ferreira Fonseca, Teresa Maria Antunes Miranda, José Paulo Achando Silva Moura
Mirror syndrome is a rare disease with unknown pathophysiology that can be present in different diseases that can cause fetal hydrops. The prognosis is usually bad with a high perinatal mortality. We report an unusual form of mirror syndrome that manifested itself only after a successful treatment for fetal hydrops (caused by twin-twin transfusion syndrome, in Quinteros stage IV) was performed. This syndrome was controlled by medical treatment, and despite the usually bad prognosis seen in these cases, we could extend the pregnancy from the 23rd to the 34th week of gestation, resulting in the birth of 2 live infants...
November 2016: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/28002112/wet-peeling-technique-of-deep-anterior-lamellar-keratoplasty-with-hypotonic-water-and-blunt-dissection-for-healed-hydrops
#14
Zelin Zhao, Jinyang Li, Qinxiang Zheng, Wei Lin, Vishal Jhanji, Wei Chen
PURPOSE: To describe the surgical technique and outcomes of "wet-peeling" deep anterior lamellar keratoplasty (DALK) using sterile water and blunt dissection in cases with corneal scarring after healed corneal hydrops. METHODS: Manual DALK using a "wet-peeling" technique was performed in 20 eyes of 20 consecutive patients with healed corneal hydrops between June 2011 and October 2013. RESULTS: Intraoperative microperforations were encountered in 2 (10%) cases...
December 20, 2016: Cornea
https://www.readbyqxmd.com/read/27999985/mri-of-endolymphatic-hydrops-in-patients-with-meniere-s-disease-a-case-controlled-study-with-a-simplified-classification-based-on-saccular-morphology
#15
Arnaud Attyé, Michael Eliezer, Naïla Boudiaf, Irène Tropres, David Chechin, Sébastien Schmerber, Georges Dumas, Alexandre Krainik
OBJECTIVES: Endolymphatic hydrops (EH) can be studied in patients by MRI. With the semi-quantitative grading system, previous imaging studies showed discrepancies in the occurrence and grading of EH in patients with Meniere's disease (MD). Here, we compared the inversion of the saccule to utricle area ratio (SURI) with the semi-quantitative method of grading conventionally used to diagnose MD. METHODS: Imaging was carried out on a 3-T MRI scanner. We performed 3D-FLAIR sequences 4 h after a single intravenous dose of contrast agent...
December 20, 2016: European Radiology
https://www.readbyqxmd.com/read/27998309/a-subserosal-pedunculated-multilocular-uterine-leiomyoma-with-ovarian-tumor-like-morphology-and-histological-architecture-of-adenomatoid-tumors-a-case-report-and-review-of-the-literature
#16
Kenji Yorita, Yu Tanaka, Koki Hirano, Yuka Kai, Kaoru Arii, Kimiko Nakatani, Satoshi Ito, Toshiya Imai, Masaharu Fukunaga, Naoto Kuroda
BACKGROUND: Uterine leiomyomas are common uterine tumors, and typical cases of leiomyoma are easily diagnosed by imaging study. However, uterine leiomyomas are often altered by degenerative changes, which can cause difficulty and confusion in their clinical diagnosis. We describe the 17th reported case of a uterine leiomyoma clinically diagnosed as an ovarian tumor; however, the present case shows the most detailed radiological evaluation, including contrast-enhanced magnetic resonance imaging...
December 20, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27997441/fatal-congenital-retroperitoneal-neuroblastoma-diagnosed-by-fetal-magnetic-resonance-imaging
#17
Elizabeth Snyder, Angie C Jelin, Thierry A G M Huisman, Jody E Hooper, Aylin Tekes
Congenital extra-adrenal neuroblastoma is a rare condition, which typically has a favorable prognosis. We present a unique case of extra-adrenal retroperitoneal neuroblastoma diagnosed by fetal magnetic resonance imaging, which ultimately leads to fetal hydrops and neonatal death.
December 15, 2016: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/27987334/echocardiography-findings-in-a-case-with-ballantyne-syndrome
#18
Yutaro Suzuki, Mie Yamamura, Keisuke Kikuchi, Rifumi Hattori, Takeshi Umazume, Hisanori Minakami
Marked fluid retention occurs in Ballantyne syndrome, but few reports are available on changes in cardiac morphology in this syndrome. A woman with generalized edema, dyspnea, fetal hydrops (skin edema and ascites), thickened placenta, and elevated plasma B-type natriuretic peptide level (344 pg/mL) was admitted to our hospital at gestational week (GW) 20(+3) . Blood pressure remained within the normal range. However, acute increases in left atrial volume index, pulmonary artery systolic pressure, and hyperdynamic left ventricular function (as evidenced by increased left ventricular ejection fraction to 74% with cardiac index of 5...
December 17, 2016: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/27987045/continuous-fetal-head-flexion-as-a-marker-for-prenatal-diagnosis-of-lethal-multiple-pterygium-syndrome-a-case-report
#19
Akihiro Hasegawa, Mieko Hanaoka, Takeshi Murakoshi
Lethal multiple pterygium syndrome (LMPS) is a fatal hereditary disease associated with abnormalities such as pterygium-induced congenital contractures. Fetal hydrops is present in more than half of all patients with LMPS, and all patients with LMPS are either stillborn or die in the early neonatal period. Ultrasonography findings for the prenatal diagnosis of LMPS include the detection of cutaneous webbing at multiple joints, multiple joint contractures, absent limb movement, and increased nuchal translucency...
December 16, 2016: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/27983637/limited-link-between-oxidative-stress-and-ochratoxin-a-induced-renal-injury-in-an-acute-toxicity-rat-model
#20
Liye Zhu, Tao Yu, Xiaozhe Qi, Jing Gao, Kunlun Huang, Xiaoyun He, Haoshu Luo, Wentao Xu
Ochratoxin A (OTA) displays nephrotoxicity and hepatotoxicity. However, in the acute toxicity rat model, there is no evidence on the relationship between OTA and nephrotoxicity and hepatotoxicity. Based on this, the integrated analysis of physiological status, damage biomarkers, oxidative stress, and DNA damage were performed. After OTA treatment, the body weight decreased and AST, ALP, TP, and BUN levels in serum increased. Hydropic degeneration, swelling, vacuolization, and partial drop occurred in proximal tubule epithelial cells...
December 14, 2016: Toxins
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