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Gastric Bypass Surgery

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https://www.readbyqxmd.com/read/28429199/gastric-bypass-and-influence-on-improvement-of-nafld
#1
REVIEW
Vamsi Alli, Ann M Rogers
PURPOSE OF REVIEW: Obesity is recognized as a chronic and recurring disease, often accompanied by other weight-related comorbid conditions such as obstructive sleep apnea, hypertension, type 2 diabetes, and non-alcoholic fatty liver disease (NAFLD). This chapter will seek to focus on the effect of weight loss surgery (WLS), in particular Roux-en-Y gastric bypass (RYGB), on NAFLD. RECENT FINDINGS: Among several modalities available to treat NAFLD, the one most likely to achieve rapid, significant, and sustained improvement of liver disease is WLS...
June 2017: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/28421792/micronutrient-supplementation-in-gastric-bypass-surgery-prospective-study-on-in%C3%AF-ammation-and-iron-metabolism-in-premenopausal-women
#2
Flávia Andréia Marin, Rozangela Verlengia, Alex Harley Crisp, Patrícia Fátima Sousa Novais, Irineu Rasera-Junior, Maria Rita Marques De Oliveira
BACKGROUND: Low-grade chronic inflammation in morbid obesity is associated with impaired iron metabolism. Bariatric surgery is effective in weight loss; however, it can induce specific nutritional deficiencies, such as iron, especially in premenopausal women. Alternatively, after surgery, there is an improvement in systemic inflammation, raising questions concerning the dosages of micronutrient supplementation. OBJECTIVES: This study aimed to assess the effect of two micronutrient supplementation schemes before and 6 months after a Roux-en-Y gastric bypass (RYGB) surgery on inflammation and iron metabolism in premenopausal women...
March 30, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28420586/impaired-oral-absorption-of-methylphenidate-after-roux-en-y-gastric-bypass
#3
REVIEW
Carmil Azran, Peter Langguth, Arik Dahan
The anatomic and physiologic changes in the gastrointestinal (GI) tract after bariatric surgery may significantly affect the pharmacokinetics of medications taken by the patients for various reasons. Unfortunately, there is little information regarding changes in drug absorption after bariatric surgeries, limiting the ability of medical professionals to produce clear recommendations on what changes should be made to the formulations and dosing regimens of drugs after bariatric surgery. In this article, we report and analyze a case of 52-year-old male patient with morbid obesity and attention-deficit/hyperactivity disorder (ADHD) who experienced lack of methylphenidate efficacy after Roux en-Y gastric bypass (RYGB), which was eventually resolved by using the transdermal patch instead of an oral product...
March 9, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28419237/the-fat-score-a-fibrosis-score-of-adipose-tissue-predicting-weight-loss-outcome-after-gastric-bypass
#4
Pierre Bel Lassen, Frederic Charlotte, Yuejun Liu, Pierre Bedossa, Gilles le Naour, Joan Tordjman, Christine Poitou, Jean-Luc Bouillot, Laurent Genser, Jean-Daniel Zucker, Nataliya Sokolovska, Judith Aron-Wisnewsky, Karine Clément
Context: Bariatric surgery (BS) induces major and sustainable weight loss in many but not all patients. Factors predicting poor responders (PR) need to be identified to improve patient care. Quantification of subcutaneous adipose tissue (scAT) fibrosis is negatively associated with post-BS weight loss, but whether it could constitute a predictor applicable in clinical routine remains to be demonstrated. Objective: To create a semi-quantitative score evaluating scAT fibrosis and test its predictive value on weight loss response after Roux-en-Y gastric bypass (RYGB)...
April 17, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28411313/roux-en-y-gastric-bypass-and-sleeve-gastrectomy-does-not-affect-food-preferences-when-assessed-by-an-ad-libitum-buffet-meal
#5
Mette S Nielsen, Bodil J Christensen, Christian Ritz, Simone Rasmussen, Thea T Hansen, Wender L P Bredie, Carel W le Roux, Anders Sjödin, Julie B Schmidt
BACKGROUND: Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) lead to a reduction in energy intake. It is uncertain whether this reduction is simply due to eating smaller portions or if surgery changes food preferences towards less energy-dense food. Previous results rely on verbal reports, which may be prone to recall bias and underestimation of especially unhealthy foods. METHODS: Using an ad libitum buffet meal targeting direct behavior, we investigated if RYGB and SG surgery leads to changes in food preferences...
April 14, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28411021/improvement-in-cardiovascular-risk-in-women-after-bariatric-surgery-as-measured-by-carotid-intima-media-thickness-comparison-of-sleeve-gastrectomy-versus-gastric-bypass
#6
Jesús M Gómez-Martin, Enrique Aracil, Julio Galindo, Héctor F Escobar-Morreale, José A Balsa, José I Botella-Carretero
BACKGROUND: Bariatric surgery may diminish cardiovascular risk (CVR) and its associated mortality. However, studies that compare these effects with different techniques are scarce. OBJECTIVE: To evaluate the changes in CVR as estimated by carotid intima-media thickness (IMT) after obesity surgery in women with high CVR as defined by the presence of metabolic syndrome. SETTING: Academic hospital. METHODS: We studied 40 severely obese women, of whom 20 received laparoscopic Roux en Y gastric bypass (RYGB) and 20 received sleeve gastrectomy (SG)...
February 3, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28405878/bariatric-surgery-and-endoluminal-procedures-ifso-worldwide-survey-2014
#7
L Angrisani, A Santonicola, P Iovino, A Vitiello, N Zundel, H Buchwald, N Scopinaro
BACKGROUND AND AIM: Several bariatric surgery worldwide surveys have been previously published to illustrate the evolution of bariatric surgery in the last decades. The aim of this survey is to report an updated overview of all bariatric procedures performed in 2014.For the first time, a special section on endoluminal techniques was added. METHODS: The 2014 International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO) survey form evaluating the number and the type of surgical and endoluminal bariatric procedures was emailed to all IFSO societies...
April 13, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28403093/jejunojejunal-intussusception-after-roux-en-y-gastric-bypass-in-a-situs-inversus-totalis-patient-a-case-report
#8
Guangyi Jiang, Baojuan Fu, Sheng Lv, Junjie Hong, Xiujun Cai
INTRODUCTION: Situs inversus totalis (SIT) is an uncommon clinical manifestation. Patients with SIT typically have malformation in the thorax and abdomen. The incidence of SIT ranges from 1/10,000 to 1/20,000 (Al-Jumaily and Hoche. J Laparoendosc Adv Surg Tech A 2001;11:229). Jejunojejunal intussusception is a rare complication after Roux-en-Y gastric bypass. Intussusception in adult cases accounts for 5% of adult intestinal obstruction cases, while in children, the occurrence is high and the majority of them are idiopathic cases...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28400396/giant-perforated-marginal-ulcer-after-laparoscopic-roux-en-y-gastric-bypass
#9
Edward Wang, Ruth Blackham, Jeremy Tan, Jeffrey Hamdorf
Perforation of a marginal ulcer (MU) is a complication of Roux-en-Y gastric bypass that can be life-threatening. We report a case of a perforated MU that presented 7 months after surgery with several interesting points for discussion. Firstly, the presentation of the ulcer was cryptic with unreliable investigations. Secondly, the ulcer presented again even after anastomotic revision surgery. Finally, the ulcer and the sepsis associated with perforation presented after months of poor nutritional intake with profound hypoalbuminaemia...
April 11, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28397104/omeprazole-absorption-and-fasting-gastrinemia-after-roux-en-y-gastric-bypass
#10
Renata V A Collares-Pelizaro, José S Santos, Carla B Nonino, Cristiane M Gaitani, Wilson Salgado
PURPOSE: Roux-en-Y gastric bypass (RYGB) is one of the bariatric surgeries most frequently performed worldwide. Since this operation may predispose to the formation of peptic ulcer of the gastrojejunal anastomosis, the use of proton pump inhibitors (PPI) is recommended during the first postoperative year. However, so far, there is no detailed knowledge about the absorption of this medication during the immediate postoperative period and consequently about its effectiveness in blocking acid secretion...
April 10, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28396972/prevalence-and-associated-factors-of-obstructive-sleep-apnea-in-morbidly-obese-patients-undergoing-bariatric-surgery
#11
Weerapat Kositanurit, Dittapol Muntham, Suthep Udomsawaengsup, Naricha Chirakalwasan
PURPOSE: Our goal in this study is to determine the prevalence and associated factors of obstructive sleep apnea (OSA) in morbidly obese patients undergoing bariatric surgery. METHODS: This descriptive study was conducted at King Chulalongkorn Memorial Hospital from 2007 to 2015. Data of morbidly obese patients who underwent bariatric surgery were included using ICD-10 code for principle diagnosis "morbid obesity" (E668) and ICD-9 code for "bariatric surgery" (4389, 4438, 4439)...
April 11, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28396129/bariatric-surgery-in-young-adults-a-multicenter-study-into-weight-loss-dietary-adherence-and-quality-of-life
#12
Marjolein M C de Jong, Chris Hinnen
BACKGROUND: Numerous studies have demonstrated that bariatric surgery is an effective intervention for morbid obesity, but study samples are characterized by an underrepresentation of young adult patients. OBJECTIVES: The aim of this study was to evaluate weight loss, dietary adherence, and quality of life (QoL) in a multicenter, young adult sample, in the first 6 years after bariatric surgery. SETTING: Four general hospitals in the Netherlands...
March 7, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28394957/-intestinal-failure-due-to-short-bowel-syndrome-impact-of-a-multidisciplinary-intestinal-rehabilitation-program
#13
María Elena Molina, Felipe Bellolio, Julieta Klaassen, Javier Gómez, Constanza Villalón, Juan Francisco Guerra, Álvaro Zúñiga
BACKGROUND: In patients suffering intestinal failure due to short bowel, the goal of an Intestinal Rehabilitation Program is to optimize and tailor all aspects of clinical management, and eventually, wean patients off lifelong parenteral nutrition. AIM: To report the results of our program in patients suffering intestinal failure. PATIENTS AND METHODS: A registry of all patients referred to the Intestinal Failure unit between January 2009 and December 2015 was constructed...
November 2016: Revista Médica de Chile
https://www.readbyqxmd.com/read/28392935/measurement-of-hepatic-insulin-sensitivity-early-after-the-bypass-of-the-proximal-small-bowel-in-humans
#14
A D Miras, R Herring, A Vusirikala, F Shojaee-Moradi, N C Jackson, S Chandaria, S N Jackson, A P Goldstone, N Hakim, A G Patel, A M Umpleby, C W Le Roux
OBJECTIVE: Unlike gastric banding or sleeve gastrectomy procedures, intestinal bypass procedures, Roux-en-Y gastric bypass in particular, lead to rapid improvements in glycaemia early after surgery. The bypass of the proximal small bowel may have weight loss and even caloric restriction-independent glucose-lowering properties on hepatic insulin sensitivity. In this first human mechanistic study, we examined this hypothesis by investigating the early effects of the duodeno-jejunal bypass liner (DJBL; GI Dynamics, USA) on the hepatic insulin sensitivity by using the gold standard euglycaemic hyperinsulinaemic clamp methodology...
March 2017: Obesity Science & Practice
https://www.readbyqxmd.com/read/28392254/american-society-for-metabolic-and-bariatric-surgery-integrated-health-nutritional-guidelines-for-the-surgical-weight-loss-patient-2016-update-micronutrients
#15
Julie Parrott, Laura Frank, Rebecca Rabena, Lillian Craggs-Dino, Kellene A Isom, Laura Greiman
BACKGROUND: Optimizing postoperative patient outcomes and nutritional status begins preoperatively. Patients should be educated before and after weight loss surgery (WLS) on the expected nutrient deficiencies associated with alterations in physiology. Although surgery can exacerbate preexisting nutrient deficiencies, preoperative screening for vitamin deficiencies has not been the norm in the majority of WLS practices. Screening is important because it is common for patients who present for WLS to have at least 1 vitamin or mineral deficiency preoperatively...
January 19, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28391439/one-anastomosis-gastric-bypass-first-407-patients-in-1%C3%A2-year
#16
Yonatan Lessing, Niv Pencovich, Marian Khatib, Shai Meron-Eldar, Joseph Koriansky, Subhi Abu-Abeid
BACKGROUND: One-anastomosis gastric bypass (OAGB) is a promising laparoscopic procedure with various benefits including shorter operating times and less operative complications. That said, it is yet to gain widespread acceptance. Here, we describe our first-year experience with OAGB in our department, in particular the safety and efficacy of this procedure. METHODS: This study is a retrospective analysis of all patients who underwent OAGB between March 2015 and March 2016 by our bariatric surgery unit...
April 8, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28390813/bile-acids-and-bariatric-surgery
#17
REVIEW
Vance L Albaugh, Babak Banan, Hana Ajouz, Naji N Abumrad, Charles R Flynn
Bariatric surgery, specifically Roux-en-Y gastric bypass (RYGB) and vertical sleeve gastrectomy (VSG), are the most effective and durable treatments for morbid obesity and potentially a viable treatment for type 2 diabetes (T2D). The resolution rate of T2D following these procedures is between 40 and 80% and far surpasses that achieved by medical management alone. The molecular basis for this improvement is not entirely understood, but has been attributed in part to the altered enterohepatic circulation of bile acids...
April 5, 2017: Molecular Aspects of Medicine
https://www.readbyqxmd.com/read/28388388/hypoglycemia-after-gastric-bypass-an-emerging-complication
#18
REVIEW
Richard Millstein, Helen M Lawler
As the obesity epidemic worsens, more people are opting for weight-loss surgery, including gastric bypass. Of the possible complications associated with this procedure, hypoglycemia secondary to hyperinsulinemia is becoming a more common and therefore more relevant problem.
April 2017: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/28386755/rygb-produces-more-sustained-body-weight-loss-and-improvement-of-glycemic-control-compared-with-vsg-in-the-diet-induced-obese-mouse-model
#19
Zheng Hao, R Leigh Townsend, Michael B Mumphrey, Christopher D Morrison, Heike Münzberg, Hans-Rudolf Berthoud
BACKGROUND: Weight regain and type-2 diabetes relapse has been reported in a significant proportion of vertical sleeve gastrectomy (VSG) patients in some studies, but definitive conclusions regarding the long-term comparative effectiveness of VSG and Roux-en-Y gastric bypass (RYGB) surgery are lacking both in humans and rodent models. This study's objective was to compare the effects of murine models of VSG and RYGB surgery on body weight, body composition, food intake, energy expenditure, and glycemic control...
April 6, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28386664/determinants-of-glomerular-filtration-rate-following-bariatric-surgery-in-individuals-with-severe-otherwise-uncomplicated-obesity-an-observational-prospective-study
#20
Marta Seghieri, Edoardo Vitolo, Livia Giannini, Eleonora Santini, Chiara Rossi, Antonio Salvati, Anna Solini
AIMS: Obesity-induced nephropathy is an established clinical entity arising from a "maladaptive" response to lipid accumulation at the nephron level. Bariatric surgery positively affects renal function, reducing or increasing glomerular filtration rate (GFR) in subjects with hyperfiltration and renal impairment, respectively. The effect of this surgery in patients with normal estimated GFR (eGFR) is less clear. METHODS: A complete clinical and biochemical assessment of 135 severely obese, otherwise healthy subjects, was obtained before Roux-en-Y gastric bypass (RYGB)...
April 6, 2017: Acta Diabetologica
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