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https://www.readbyqxmd.com/read/29667836/molecular-dynamics-simulations-are-redefining-our-view-of-peptides-interacting-with-biological-membranes
#1
Jakob P Ulmschneider, Martin B Ulmschneider
Ever since the first molecular mechanics computer simulations of biological molecules became possible, there has been the dream to study all complex biological phenomena in silico, simply bypassing the enormous experimental challenges and their associated costs. For this, two inherent requirements need to be met: First, the time scales achievable in simulations must reach up to the millisecond range and even longer. Second, the computational model must accurately reproduce what is measured experimentally. Despite some recent successes, the general consensus in the field to date has been that neither of these conditions have yet been met and that the dream will be realized, if at all, only in the distant future...
April 18, 2018: Accounts of Chemical Research
https://www.readbyqxmd.com/read/29667034/thermal-comfort-along-the-marathon-course-of-the-2020-tokyo-olympics
#2
Tsuyoshi Honjo, Yuhwan Seo, Yudai Yamasaki, Nobumitsu Tsunematsu, Hitoshi Yokoyama, Hiroaki Yamato, Takehiko Mikami
The Olympic Games will be held in Tokyo in 2020 and the period will be the hottest period of the year in Japan. Marathon is a sport with a large heat load, and it is said that the risk of heat stroke rises more than other sports activities. The thermal environment of the 2020 Tokyo Olympic marathon course is analyzed by using wet-bulb globe temperature (WBGT) and Universal Thermal Climate Index (UTCI) map of the center area of Tokyo. The change due to the place, the effect of the shadow of the building, and the position on the course was analyzed from the distribution of WBGT and UTCI in the short-term analysis of sunny day from August 2 to August 6, 2014...
April 17, 2018: International Journal of Biometeorology
https://www.readbyqxmd.com/read/29666748/mass-gathering-enhanced-syndromic-surveillance-for-the-8th-micronesian-games-in-2014-pohnpei-state-federated-states-of-micronesia
#3
Paul White, Salanieta Saketa, Eliaser Johnson, Sameer V Gopalani, Eliashib Edward, Charles Loney, Alize Mercier, Tebuka Toatu, Richard Wojcik, Sheri Lewis, Damian Hoy
Pohnpei State's Division of Primary Health Care implemented enhanced surveillance for early warning and detection of disease to support the 8th Micronesian Games (the Games) in July 2014. The surveillance comprised 11 point-of-care sentinel sites around Pohnpei, Federated States of Micronesia, collecting data daily for eight syndromes using standard case definitions. Each sentinel site reported total acute care encounters, total syndrome cases and the total for each syndrome. A public health response, including epidemiological investigation and laboratory testing, followed when syndrome counts reached predetermined threshold levels...
January 2018: Western Pacific Surveillance and Response Journal: WPSAR
https://www.readbyqxmd.com/read/29666588/increased-insular-cortical-thickness-associated-with-symptom-severity-in-male-youths-with-internet-gaming-disorder-a-surface-based-morphometric-study
#4
Shuai Wang, Jing Liu, Lin Tian, Limin Chen, Jun Wang, Qunfeng Tang, Fuquan Zhang, Zhenhe Zhou
With the rising increase in Internet-usage, Internet gaming disorder (IGD) has gained massive attention worldwide. However, detailed cerebral morphological changes remain unclear in youths with IGD. In the current study, our aim was to investigate cortical morphology and further explore the relationship between the cortical morphology and symptom severity in male youths with IGD. Forty-eight male youths with IGD and 32 age- and education-matched normal controls received magnetic resonance imaging scans. We employed a recently proposed surface-based morphometric approach for the measurement of cortical thickness (CT)...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29666566/-enheduanna-a-manifesto-of-falling-live-brain-computer-cinema-performance-performer-and-audience-participation-cognition-and-emotional-engagement-using-multi-brain-bci-interaction
#5
Polina Zioga, Frank Pollick, Minhua Ma, Paul Chapman, Kristian Stefanov
The fields of neural prosthetic technologies and Brain-Computer Interfaces (BCIs) have witnessed in the past 15 years an unprecedented development, bringing together theories and methods from different scientific fields, digital media, and the arts. More in particular, artists have been amongst the pioneers of the design of relevant applications since their emergence in the 1960s, pushing the boundaries of applications in real-life contexts. With the new research, advancements, and since 2007, the new low-cost commercial-grade wireless devices, there is a new increasing number of computer games, interactive installations, and performances that involve the use of these interfaces, combining scientific, and creative methodologies...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29665760/nintendo-wii%C3%A2-versus-xbox-kinect%C3%A2-for-assisting-people-with-parkinson-s-disease
#6
Melissa L M Alves, Beatriz S Mesquita, Wenderson S Morais, Josevan C Leal, Corina E Satler, Felipe A Dos Santos Mendes
This study investigated changes in motor and cognitive skills, anxiety levels, and quality of life perception among patients with Parkinson's Disease (PD) following training with different commercial gaming devices-Nintendo Wii™ and Xbox Kinect™. We used a quasi-experimental, simple blinded clinical trial, dividing 27 patients with PD into three equal groups of nine members: (a) Nintendo Wii™, (b) Xbox Kinect™, and (c) control group. After pretests, experimental group participants spent 10 sessions playing four games of the selected gaming device, while control group participants received no intervention...
January 1, 2018: Perceptual and Motor Skills
https://www.readbyqxmd.com/read/29664349/signaling-games-and-the-evolution-of-structure-in-language-and-music-a-reply-to-ravignani-and-verhoef-2018-%C3%A2
#7
Massimo Lumaca, Giosuè Baggio
In their commentary on our work, Ravignani and Verhoef (2018) raise concerns about two methodological aspects of our experimental paradigm (the signaling game): (1) the use of melodic signals of fixed length and duration, and (2) the fact that signals are endowed with meaning. They argue that music is hardly a semantic system and that our methodological choices may limit the capacity of our paradigm to shed light on the emergence and evolution of a number of putative musical universals. We reply that musical systems are semantic systems and that the aim of our research is not to study musical universals as such, but to compare more closely the kinds of principles that organize meaning and structure in linguistic and musical systems...
April 17, 2018: Artificial Life
https://www.readbyqxmd.com/read/29664347/which-melodic-universals-emerge-from-repeated-signaling-games-a-note-on-lumaca-and-baggio-2017-%C3%A2
#8
Andrea Ravignani, Tessa Verhoef
Music is a peculiar human behavior. While very common in our species, we still know very little as to why and how music emerged. For centuries, the study of music has been the sole prerogative of the humanities. Lately, however, music is being increasingly investigated by psychologists, neuroscientists, biologists, and computer scientists. One possible approach to study the origins of music is to hypothesize and empirically test the mechanisms behind this structured behavior. Recent experiments in the lab have shown how musical rhythm and melody can emerge via the process of cultural transmission...
April 17, 2018: Artificial Life
https://www.readbyqxmd.com/read/29664346/an-agent-based-model-for-the-role-of-short-term-memory-enhancement-in-the-emergence-of-grammatical-agreement
#9
Javier Vera
What is the influence of short-term memory enhancement on the emergence of grammatical agreement systems in multi-agent language games? Agreement systems suppose that at least two words share some features with each other, such as gender, number, or case. Previous work, within the multi-agent language-game framework, has recently proposed models stressing the hypothesis that the emergence of a grammatical agreement system arises from the minimization of semantic ambiguity. On the other hand, neurobiological evidence argues for the hypothesis that language evolution has mainly related to an increasing of short-term memory capacity, which has allowed the online manipulation of words and meanings participating particularly in grammatical agreement systems...
April 17, 2018: Artificial Life
https://www.readbyqxmd.com/read/29664176/motor-performance-in-early-life-and-participation-in-leisure-time-physical-activity-up-to-age-68-years
#10
Ahmed Elhakeem, Rebecca Hardy, David Bann, Diana Kuh, Rachel Cooper
BACKGROUND: This study examined associations between motor performance in early life and leisure-time physical activity (LTPA) participation across adulthood, and whether these changed with age. METHODS: Data were from 2526 participants from the Medical Research Council National Survey of Health and Development. Motor indicators were mother-reported ages at first standing and walking, teacher-rated games ability at age 13, and finger- and foot-tapping speed at age 15...
April 17, 2018: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/29663980/evaluation-of-nighttime-media-use-and-sleep-patterns-in-first-semester-college-students
#11
Jonathon Whipps, Mark Byra, Kenneth G Gerow, Emily Hill Guseman
OBJECTIVE: We evaluated how nighttime media use is associated with sleep behaviors in firstsemester college students, and variation by weight status. METHODS: In September 2016, first-semester college students (N = 114) completed surveys evaluating nighttime media usage (NMU) and sleep behaviors. Height, weight, and waist circumference were measured, and weight status was determined by body mass index. RESULTS: Students reported a mean sleep duration of 7...
May 1, 2018: American Journal of Health Behavior
https://www.readbyqxmd.com/read/29663149/elevated-parasite-burdens-as-a-potential-mechanism-affecting-northern-bobwhite-colinus-virginianus-population-dynamics-in-the-rolling-plains-of-west-texas
#12
Matthew Z Brym, Cassandra Henry, Ronald J Kendall
Northern bobwhite quail (Colinus virginianus) are a highly sought-after game bird in the Rolling Plains of West Texas. Unfortunately, bobwhite populations in this area are subject to dramatic fluctuations and have been steadily decreasing over the past several decades. While many factors have been investigated as potential mechanisms of cyclic and declining bobwhite numbers, the effect of parasites on bobwhite populations has historically been undervalued. Between December 2017 and February 2018, we received 21 hunter-shot bobwhite from Garza and Mitchell counties in Texas and found peak caecal worm (Aulonocephalus pennula) and eyeworm (Oxyspirura petrowi) burdens averaging 599 and 44, respectively...
April 17, 2018: Parasitology Research
https://www.readbyqxmd.com/read/29662911/unaccounted-workload-factor-game-day-pitch-counts-in-high-school-baseball-pitchers-an-observational-study
#13
Jason L Zaremski, Giorgio Zeppieri, Deborah L Jones, Brady L Tripp, Michelle Bruner, Heather K Vincent, MaryBeth Horodyski
Background: Throwing injuries are common in high school baseball. Known risk factors include excessive pitch counts, year-round pitching, and pitching with arm pain and fatigue. Despite the evidence, the prevalence of pitching injuries among high school players has not decreased. One possibility to explain this pattern is that players accumulate unaccounted pitch volume during warm-up and bullpen activity, but this has not yet been examined. Hypotheses: Our primary hypothesis was that approximately 30% to 40% of pitches thrown off a mound by high school pitchers during a game-day outing are unaccounted for in current data but will be revealed when bullpen sessions and warm-up pitches are included...
April 2018: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29661748/virtual-reality-cue-refusal-video-game-for-alcohol-and-cigarette-recovery-support-summative-study
#14
Mary Metcalf, Karen Rossie, Katie Stokes, Christina Tallman, Bradley Tanner
BACKGROUND: New technologies such as virtual reality, augmented reality, and video games hold promise to support and enhance individuals in addiction treatment and recovery. Quitting or decreasing cigarette or alcohol use can lead to significant health improvements for individuals, decreasing heart disease risk and cancer risks (for both nicotine and alcohol use), among others. However, remaining in recovery from use is a significant challenge for most individuals. OBJECTIVE: We developed and assessed the Take Control game, a partially immersive Kinect for Windows platform game that allows users to counter substance cues through active movements (hitting, kicking, etc)...
April 16, 2018: JMIR Serious Games
https://www.readbyqxmd.com/read/29661133/the-impact-of-genome-editing-on-the-introduction-of-monogenic-traits-in-livestock
#15
John W M Bastiaansen, Henk Bovenhuis, Martien A M Groenen, Hendrik-Jan Megens, Han A Mulder
BACKGROUND: Genome editing technologies provide new tools for genetic improvement and have the potential to become the next game changer in animal and plant breeding. The aim of this study was to investigate how genome editing in combination with genomic selection can accelerate the introduction of a monogenic trait in a livestock population as compared to genomic selection alone. METHODS: A breeding population was simulated under genomic selection for a polygenic trait...
April 16, 2018: Genetics, Selection, Evolution: GSE
https://www.readbyqxmd.com/read/29659539/post-game-high-protein-intake-may-improve-recovery-of-football-specific-performance-during-a-congested-game-fixture-results-from-the-pro-football-study
#16
Athanasios Poulios, Ioannis G Fatouros, Magni Mohr, Dimitrios K Draganidis, Chariklia Deli, Konstantinos Papanikolaou, Apostolos Sovatzidis, Theofano Nakopoulou, Georgios Ermidis, Theofanis Tzatzakis, Vasiliki C Laschou, Kalliopi Georgakouli, Agisilaos Koulouris, Panagiotis Tsimeas, Athanasios Chatzinikolaou, Leonidas G Karagounis, Dimitrios Batsilas, Peter Krustrup, Athanasios Z Jamurtas
The effects of protein supplementation on performance recovery and inflammatory responses during a simulated one-week in-season microcycle with two games (G1, G2) performed three days apart were examined. Twenty football players participated in two trials, receiving either milk protein concentrate (1.15 and 0.26 g/kg on game and training days, respectively) (PRO) or an energy-matched placebo (1.37 and 0.31 g/kg of carbohydrate on game and training days, respectively) (PLA) according to a randomized, repeated-measures, crossover, double-blind design...
April 16, 2018: Nutrients
https://www.readbyqxmd.com/read/29659101/lessons-from-queensland-s-last-drinks-legislation-the-use-of-extended-trading-permits
#17
Renee Zahnow, Peter Miller, Kerri Coomber, Dominique de Andrade, Jason Ferris
INTRODUCTION AND AIMS: The association between alcohol availability, alcohol consumption and, in turn, alcohol-related harms is well established. Policies to reduce alcohol-related harms focus on limiting accessibility through the regulation of the liquor industry, including trading hours. On 1 July 2016, the Queensland Government introduced legislation to reduce ordinary liquor trading hours, replacing 5 am closing times with 3 am cessation of liquor sales in designated entertainment precincts and 2 am cessation of sales across the rest of the state...
April 16, 2018: Drug and Alcohol Review
https://www.readbyqxmd.com/read/29658807/effect-of-bright-light-therapy-on-delayed-sleep-wake-cycle-and-reaction-time-of-athletes-participating-in-the-rio-2016-olympic-games
#18
João Paulo P Rosa, Andressa Silva, Dayane F Rodrigues, Mário Antônio Simim, Fernanda V Narciso, Sergio Tufik, Jorge J Bichara, Sebastian Rafael D Pereira, Sidney C Da Silva, Marco Tulio de Mello
This study investigated the effect of using an artificial bright light on the entrainment of the sleep/wake cycle as well as the reaction times of athletes before the Rio 2016 Olympic Games. A total of 22 athletes from the Brazilian Olympic Swimming Team were evaluated, with the aim of preparing them to compete at a time when they would normally be about to go to bed for the night. During the 8-day acclimatization period, their sleep/wake cycles were assessed by actigraphy, with all the athletes being treated with artificial light therapy for between 30 and 45 min (starting at day 3)...
April 16, 2018: Chronobiology International
https://www.readbyqxmd.com/read/29657810/how-successful-are-mutants-in-multiplayer-games-with-fluctuating-environments-sojourn-times-fixation-and-optimal-switching
#19
Joseph W Baron, Tobias Galla
Using a stochastic model, we investigate the probability of fixation, and the average time taken to achieve fixation, of a mutant in a population of wild-types. We do this in a context where the environment in which the competition takes place is subject to stochastic change. Our model takes into account interactions which can involve multiple participants. That is, the participants take part in multiplayer games. We find that under certain circumstances, there are environmental switching dynamics which minimize the time that it takes for the mutants to fixate...
March 2018: Royal Society Open Science
https://www.readbyqxmd.com/read/29657481/getting-back-in-the-game-after-humeral-head-resurfacing
#20
Matthias Bülhoff, Boris Sowa, Thomas Bruckner, Patric Raiss, Felix Zeifang
Background: Aim of this investigation was to analyze whether patients undergoing humeral head resurfacing (HHR) surgery are able to successfully return to their sports and occupation afterwards. Materials and methods: Fifty patients treated with CUP (HHR) arthroplasty were included. Two groups were built: Patients who have participated in sports less than 5 years prior surgery (Group 1: n = 42 (84%)) and patients who have never participated in sports (Group 2: n = 8 (16%))...
March 2018: Journal of Orthopaedics
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