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https://www.readbyqxmd.com/read/29221932/evaluation-of-guidelines-for-surgical-management-of-urolithiasis
#1
Benjamin Pradère, Steeve Doizi, Silvia Proietti, Jan Brachlow, Olivier Traxer
PURPOSE: Many urological societies have provided evidence-based guidelines to help the urologist in making therapeutic choices. However, the recommendations given by these guidelines may be heterogeneous because they have been developed using a variety of methods. The objective of this study was to review key guidelines on the surgical management of urinary stones to provide practical guidance for clinical application. MATERIALS AND METHODS: Guidelines on urolithiasis from all international urological societies were searched through the society websites...
December 5, 2017: Journal of Urology
https://www.readbyqxmd.com/read/29221587/histoire-du-thermal%C3%A3-sme-%C3%A3-av%C3%A3-ne-les-bains-et-gen%C3%A3-se-de-l%C3%A2-eau-thermale-d%C3%A2-av%C3%A3-ne-history-of-thermalism-at-av%C3%A3-ne-les-bains-and-genesis-of-the-av%C3%A3-ne-thermal-spring-water
#2
B Selas
Avene thermal spring water is recognized for more than two centuries for its benefits on skin diseases. Since 1975, the Pierre Fabre Group has modernized the facilities, and developed the brand « Eau Thermal Avène », allowing more than 2,500 patients/year to be treated by this therapeutic water. The regulation requires high standards on origin, bacteriological purity and physico-chemical stability. Many works have allowed us to understand its origin, its underground path and identify its specific physico-chemical profile...
January 2017: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/29198325/ercc1-as-a-prognostic-factor-for-survival-in-patients-with-advanced-urothelial-cancer-treated-with-platinum-based-chemotherapy-a-systematic-review-and-meta-analysis
#3
REVIEW
Yuksel Urun, Jeffrey J Leow, Andre P Fay, Laurence Albiges, Toni K Choueiri, Joaquim Bellmunt
BACKGROUND: The predictive role of excision repair cross-complementing group 1 (ERCC1) as a predictive factor in patients with advanced urothelial cancer (AUC) treated with platinum-based treatment is not well defined. Here, we evaluate the role of ERCC1 in patients with AUC treated with platinum-based treatment. METHODS: We performed comprehensive, systematic computerized search to identify relevant studies through Medline, Embase, Cochrane Controlled Trials Register (CCTR) databases and abstracts from American Society of Clinical Oncology (ASCO) and ASCO Genitourinary Cancers Symposium, European Society For Medical Oncology (ESMO) and European Association of Urology (EAU) meeting up to July 2015...
December 2017: Critical Reviews in Oncology/hematology
https://www.readbyqxmd.com/read/29184855/dealing-with-complex-overactive-bladder-syndrome-patient-profiles-with-focus-on-fesoterodine-in-or-out-of-the-eau-guidelines
#4
REVIEW
John Heesakkers, Montserrat Espuña Pons, Philip Toozs Hobson, Emmanuel Chartier-Kastler
Overactive bladder (OAB) syndrome is a common, complex, and challenging condition. To assist the management of these patients, the European Association of Urology (EAU) updates its guidelines annually. This review reports the presentations from the symposium titled "Dealing with complex OAB patient profiles: in or out of the EAU guidelines?" held at the 32nd EAU Annual Congress in March 2017 in London. The symposium focused on three groups of OAB patients: women who may also suffer pelvic organ prolapse, stress urinary incontinence, the genitourinary syndrome of menopause (GSM); patients at risk of cognitive impairment; and elderly patients...
2017: Research and Reports in Urology
https://www.readbyqxmd.com/read/29170696/speed-and-circuit-based-high-intensity-interval-training-on-recovery-oxygen-consumption
#5
Lindsay N Schleppenbach, Andreas B Ezer, Sarah A Gronemus, Katelyn R Widenski, Saori I Braun, Jeffrey M Janot
Due to the current obesity epidemic in the United States, there is growing interest in efficient, effective ways to increase energy expenditure and weight loss. Research has shown that high-intensity exercise elicits a higher Excess Post-Exercise Oxygen Consumption (EPOC) throughout the day compared to steady-state exercise. Currently, there is no single research study that examines the differences in Recovery Oxygen Consumption (ROC) resulting from high-intensity interval training (HIIT) modalities. The purpose of this study is to review the impact of circuit training (CT) and speed interval training (SIT), on ROC in both regular exercising and sedentary populations...
2017: International Journal of Exercise Science
https://www.readbyqxmd.com/read/29151111/readability-assessment-of-patient-education-material-published-by-german-speaking-associations-of-urology
#6
Patrick Betschart, Valentin Zumstein, Omar Hasan Ali, Hans-Peter Schmid, Dominik Abt
OBJECTIVE: To assess the readability and comprehensibility of web-based German-language patient education material (PEM) issued by urological associations. MATERIALS AND METHODS: German PEM available in June 2017 was obtained from the European Association of Urology (EAU), German (DGU), Swiss (SGU) and Austrian (ÖGU) Association of Urology websites. Each educational text was analyzed separately using 4 well-established readability assessment tools: the Amstad Test (AT), G-SMOG (SMOG), Wiener Sachtextformel (WS) and the Lesbarkeitsindex (LIX)...
November 18, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/29074050/discrepancy-between-european-association-of-urology-guidelines-and-daily-practice-in-the-management-of-non-muscle-invasive-bladder-cancer-results-of-a-european-survey
#7
Kees Hendricksen, Atiqullah Aziz, Perrine Bes, Felix K-H Chun, Jakub Dobruch, Luis A Kluth, Paolo Gontero, Andrea Necchi, Aidan P Noon, Bas W G van Rhijn, Michael Rink, Florian Roghmann, Morgan Rouprêt, Roland Seiler, Shahrokh F Shariat, Brian Qvick, Marek Babjuk, Evanguelos Xylinas
BACKGROUND: The European Association of Urology (EAU) non-muscle-invasive bladder cancer (NMIBC) guidelines are meant to help minimise morbidity and improve the care of patients with NMIBC. However, there may be underuse of guideline-recommended care in this potentially curable cohort. OBJECTIVE: To assess European physicians' current practice in the management of NMIBC and evaluate its concordance with the EAU 2013 guidelines. DESIGN, SETTING, AND PARTICIPANTS: Initial 45-min telephone interviews were conducted with 20 urologists to develop a 26-item questionnaire for a 30-min online quantitative interview...
October 23, 2017: European Urology Focus
https://www.readbyqxmd.com/read/29056505/ly6c-hi-monocytes-are-required-for-mesenchymal-stem-stromal-cell-induced-immune-tolerance-in-mice-with-experimental-autoimmune-uveitis
#8
Jung Hwa Ko, Hyun Ju Lee, Hyun Jeong Jeong, Joo Youn Oh
The cells of the innate immune system, in addition to their capacity to elicit immunity, play a substantial role in immune tolerance induction. Our group has recently shown that a distinct subset of MHC II(hi)B220(hi)CD11b(mid) suppressive macrophages is increased in the lung by intravenous (IV) administration of mesenchymal stem/stromal cells (MSC) and induces immune tolerance. Herein, we demonstrate that circulating CD11b(hi)Ly6C(hi) monocytes are precursors to MHC II(hi)B220(hi)CD11b(mid) macrophages in the lung and required for MSC-induced tolerance in a mouse model of experimental autoimmune uveitis (EAU)...
December 9, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29038541/nk-cells-are-negatively-regulated-by-scd83-in-experimental-autoimmune-uveitis
#9
Wei Lin, Xuejing Man, Peng Li, Nannan Song, Yingying Yue, Bingqing Li, Yuanbin Li, Yufei Sun, Qiang Fu
Natural killer (NK) cells represent a subset of lymphocytes that contribute to innate immunity and have been reported to play a role in autoimmune uveitis. However, the mechanisms regulating NK cellular function in this condition remain unclear. Herein, we investigated the status of NK cells in experimental autoimmune uveitis (EAU). We found that the number of CD83(+)CD3(-)NK1.1(+) cells was increased in the inflamed eyes and spleens of the EAU mouse model. At the recovery stage of EAU, serum concentrations of soluble CD83 (sCD83) were increased...
October 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28986343/treatment-of-experimental-autoimmune-uveoretinitis-with-intravitreal-injection-of-infliximab-encapsulated-in-liposomes
#10
Rui Zhang, Jiang Qian, Xiaofeng Li, Yifei Yuan
AIMS: To evaluate the safety and efficacy of intravitreal injection of liposomes encapsulating infliximab in experimental autoimmune uveoretinitis (EAU) rats. METHODS: Liposomes containing infliximab were prepared and characterised for mean particle size, entrapment efficiency, polydispersity index (PDI) and zeta potential. In vitro release profile and the stability of infliximab-lip were evaluated. EAU rats were intravitreally injected with saline, infliximab, infliximab-lip or unloaded liposomes...
October 6, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28986090/urinary-tract-infection-in-children-diagnosis-treatment-imaging-comparison-of-current-guidelines
#11
REVIEW
M Okarska-Napierała, A Wasilewska, E Kuchar
BACKGROUND AND OBJECTIVE: Urinary tract infection (UTI) is a frequent disorder of childhood, yet the proper approach for a child with UTI is still a matter of controversy. The objective of this study was to critically compare current guidelines for the diagnosis and management of UTI in children, in light of new scientific data. METHODS: An analysis was performed of the guidelines from: American Academy of Pediatrics (AAP), National Institute for Health and Care Excellence (NICE), Italian Society of Pediatric Nephrology, Canadian Paediatric Society (CPS), Polish Society of Pediatric Nephrology, and European Association of Urology (EAU)/European Society for Pediatric Urology (ESPU)...
September 19, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28958771/-ablative-therapy-in-urology-good-practice-and-perspective
#12
A Gangi, X Cathelineau, T Tricard, H Lang
INTRODUCTION: To expose the main point of discussion from present ablative therapies' guidelines and propose global perspectives. MATERIALS AND METHODS: A review of the scientific literature was performed in Medline database (http://www.ncbi.nlm.nih.gov) and Embase (http://www.embase.com/) using different associations of keywords "ablative therapy" ; "prostate cancer"; "kidney cancer"; "guidelines"; "hybrid operating room". Publications obtained were selected based on methodology, language and relevance...
September 27, 2017: Progrès en Urologie
https://www.readbyqxmd.com/read/28955337/complement-component-c4-regulates-the-development-of-experimental-autoimmune-uveitis-through-a-t-cell-intrinsic-mechanism
#13
Lingjun Zhang, Brent A Bell, Yan Li, Rachel R Caspi, Feng Lin
In addition to its conventional roles in the innate immune system, complement has been found to directly regulate T cells in the adaptive immune system. Complement components, including C3, C5, and factor D, are important in regulating T cell responses. However, whether complement component C4 is involved in regulating T cell responses remains unclear. In this study, we used a T cell-dependent model of autoimmunity, experimental autoimmune uveitis (EAU) to address this issue. We compared disease severity in wild-type (WT) and C4 knockout (KO) mice using indirect ophthalmoscopy, scanning laser ophthalmoscopy, spectral-domain optical coherence tomography, and histopathological analysis...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28952703/-complications-of-contact-ureteral-lithotripsy
#14
REVIEW
E A Mamedov, V V Dutov, V V Bazaev
Shows the current real time terminology and variants of systematization and grading of complications of contact ureteral lithotripsy (CULT). Research papers related to complications of CULT published over the last three decades were analyzed. Currently there is no clear terminology, classification, systematization and grading of CULT complications. The terms used are deficient because they do not adequately characterize specific complications of CULT. For example, some researchers define a complete ureteral avulsion as a defect at two levels, but others interpret it as a defect of the ureter at only one level...
September 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/28947304/comparison-of-the-eortc-tables-and-the-eau-categories-for-risk-stratification-of-patients-with-nonmuscle-invasive-bladder-cancer
#15
Malte Rieken, Shahrokh F Shariat, Luis Kluth, Joseph J Crivelli, Mohammad Abufaraj, Beat Foerster, Andrea Mari, Dafina Ilijazi, Pierre I Karakiewicz, Marek Babjuk, Mithat Gönen, Evanguelos Xylinas
PURPOSE: To characterize outcomes of patients with TaT1 urothelial carcinoma of the bladder stratified by the European Association of Urology (EAU) categories and to compare them with European Organization for Research and Treatment of Cancer (EORTC) risk groups to assess the rate and effect of reclassification. PATIENTS AND METHODS: A multi-institutional database of 5,122 patients with TaT1 urothelial carcinoma of the bladder who underwent transurethral resection of the bladder with or without adjuvant therapy at 8 institutions between 1996 and 2007...
September 22, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28940605/adjuvant-chemotherapy-after-radical-nephroureterectomy-does-not-improve-survival-in-patients-with-upper-tract-urothelial-carcinoma-a-joint-study-by-the-european-association-of-urology-young-academic-urologists-and-the%C3%A2-upper-tract-urothelial-carcinoma-collaboration
#16
Andrea Necchi, Salvatore Lo Vullo, Luigi Mariani, Marco Moschini, Kees Hendricksen, Michael Rink, Roman Sosnowski, Jakub Dobruch, Jay D Raman, Christopher G Wood, Vitaly Margulis, Morgan Roupret, Alberto Briganti, Francesco Montorsi, Evanguelos Xylinas, Shahrokh F Shariat
OBJECTIVE: To analyse the outcomes of adjuvant chemotherapy vs observation in a multicentre cohort of patients with upper tract urothelial carcinoma (UTUC) in order to clarify whether such patients benefit from adjuvant chemotherapy after radical nephroureterectomy (RNU). PATIENTS AND METHODS: Data from 15 centres were collected for a total of 1544 patients, treated between 2000 and 2015. Criteria for patient selection included pT2-4N0/x stage, or lymph node-positive disease, and prior RNU...
September 20, 2017: BJU International
https://www.readbyqxmd.com/read/28934212/outcome-of-papillary-versus-clear-cell-renal-cell-carcinoma-varies-significantly-in-non-metastatic-disease
#17
MULTICENTER STUDY
Nina Wagener, Dominic Edelmann, Axel Benner, Richard Zigeuner, Hendrik Borgmann, Ingmar Wolff, Laura M Krabbe, Mireia Musquera, Paolo Dell'Oglio, Umberto Capitanio, Tobias Klatte, Luca Cindolo, Matthias May, Sabine D Brookman-May
Renal cell carcinoma (RCC) comprises a heterogenous group of tumors. Traditionally, papillary RCC (pRCC) is associated with a favorable outcome compared to clear cell RCC (ccRCC), while other series report equivalent or worse prognosis. In this paper we comparatively evaluate outcome of pRCC versus ccRCC in two large multi-institutional databases (cohort study), including distribution of pRCC subtypes 1 and 2. Retrospective data of 1,943 surgically treated pRCC patients from 17 European/ North American centers between 1984-2015 were compared to 5,600 ccRCC patients from a database comprising 11 European/ North American centers (1984-2011)...
2017: PloS One
https://www.readbyqxmd.com/read/28927062/anticancer-activity-and-antioxidant-potential-of-aponogeton-undulatus-against-ehrlich-ascites-carcinoma-cells-in-swiss-albino-mice
#18
Mohammad Saifur Rahman, Mohammad Badrul Alam, Yun Hee Choi, Jin Cheol Yoo
The in vivo anticancer and in vitro antioxidant effects of the crude methanol extract of Aponogeton undulatus, in addition to its various organic fractions, were investigated. Various assay methods, including the total antioxidant capacity assay, lipid peroxidation inhibition assay, 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging assay and ferrous reducing power assessment were used to evaluate the antioxidant potential of the crude extract and its organic fractions. The ethyl acetate fraction (EAU) demonstrated the highest antioxidant capacity (175...
September 2017: Oncology Letters
https://www.readbyqxmd.com/read/28924192/short-chain-fatty-acids-ameliorate-immune-mediated-uveitis-partially-by-altering-migration-of-lymphocytes-from-the-intestine
#19
Yukiko K Nakamura, Cathleen Janowitz, Christina Metea, Mark Asquith, Lisa Karstens, James T Rosenbaum, Phoebe Lin
Short chain fatty acids (SCFA) are metabolites of intestinal bacteria resulting from fermentation of dietary fiber. SCFA are protective in various animal models of inflammatory disease. We investigated the effects of exogenous administration of SFCAs, particularly propionate, on uveitis using an inducible model of experimental autoimmune uveitis (EAU). Oral SCFA administration attenuated uveitis severity in a mouse strain-dependent manner through regulatory T cell induction among lymphocytes in the intestinal lamina propria (LPL) and cervical lymph nodes (CLN)...
September 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28922100/frequency-and-antibiotic-resistance-of-bacteria-implicated-in-community-urinary-tract-infections-in-north-aveiro-between-2011-and-2014
#20
Tânia Costa, Inês Linhares, Ricardo Ferreira, Jasmin Neves, Adelaide Almeida
AIMS: The present study aims to evaluate the predominance of uropathogens responsible for urinary tract infection (UTI) and determine their resistance patterns, to assess if the recommended empirical treatment is appropriate for the studied population. Samples were collected in Aveiro (Portugal) from an ambulatory service between June 2011 and June 2014. RESULTS: From the 4,270 positive urine samples for UTI, 3,561 (83%) were from women and only 709 (17%) were from men...
September 18, 2017: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
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