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https://www.readbyqxmd.com/read/28292388/tailored-metabolic-workup-for-urolithiasis-the-debate-continues
#1
M. Hammad Ather, M. Nasir Sulaiman, Imran Siddiqui, Tahmeena Siddiqui
Urolithiasis is one of the commonest afflictions of the urinary tract. Stones are of various chemical compositions, some share some common etiology; but most are specific to the structure and composition of stone. In view of highly recurrent nature of this condition, it is logical to have strategies for prevention. However, due to multiple factors most patients receive no or fragmented information on prevention. The current controversy is to the extent of metabolic workup in adult first time stone former. This requires longitudinal studies to show benefit in prevention strategies...
February 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28265307/antibiotic-prophylaxis-for-prevention-of-urinary-tract-infections-in-prenatal-hydronephrosis-an-updated-systematic-review
#2
REVIEW
Bethany Easterbrook, John-Paul Capolicchio, Luis H Braga
INTRODUCTION: While continuous antibiotic prophylaxis (CAP) is currently recommended to prevent urinary tract infections (UTIs) in infants with prenatal hydronephrosis (HN), this recommendation is not evidence-based. The objective of this study was to systematically determine whether CAP reduces UTIs in the HN population. METHODS: Applicable trials were identified through an electronic search of MEDLINE (1946-2015), EMBASE (1980-2016), CINAHL (1982-2016), and CENTRAL (1993-2016) and through a hand search of American Urological Association (AUA) (2012-2015) and European Society for Pediatric Urology (ESPU) (2012-2015) abstracts, as well as reference lists of included trials...
January 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28263131/factors-and-practice-patterns-that-affect-the-decision-for-vasoepididymostomy
#3
Kevin A Ostrowski, Nicholas N Tadros, A Scott Polackwich, R Dale McClure, Eugene F Fuchs, Jason C Hedges
INTRODUCTION: To determine the factors used to make the decision between vasovasostomy (VV) and vasoepididymostomy (VE) by leaders performing microsurgical vasectomy reversal using a questionnaire. MATERIALS AND METHODS: An online questionnaire was sent to all members of the Society for the Study of Male Reproduction (SSMR), a male reproduction subspecialty society of the AUA, using the SurveyMonkey platform. RESULTS: Sixty-seven surgeons responded to the questionnaire (27% of SSMR members)...
February 2017: Canadian Journal of Urology
https://www.readbyqxmd.com/read/28257121/dealing%C3%A2-with%C3%A2-an%C3%A2-unconventional%C3%A2-genetic%C3%A2-code%C3%A2-in%C3%A2-mitochondria-%C3%A2-the%C3%A2-biogenesis%C3%A2-and%C3%A2-pathogenic%C3%A2-defects%C3%A2-of%C3%A2-the%C3%A2-5-formylcytosine%C3%A2-modification%C3%A2-in%C3%A2-mitochondrial%C3%A2-trna-met
#4
REVIEW
Lindsey Van Haute, Christopher A Powell, Michal Minczuk
Human mitochondria contain their own genome, which uses an unconventional genetic code. In addition to the standard AUG methionine codon, the single mitochondrial tRNA Methionine (mt-tRNAMet) also recognises AUA during translation initiation and elongation. Post-transcriptional modifications of tRNAs are important for structure, stability, correct folding and aminoacylation as well as decoding. The unique 5-formylcytosine (f5C) modification of position 34 in mt-tRNAMet has been long postulated to be crucial for decoding of unconventional methionine codons and efficient mitochondrial translation...
March 2, 2017: Biomolecules
https://www.readbyqxmd.com/read/28248059/-extracorporeal-and-contact-lithotripsy-for-large-ureteral-stones
#5
M I Kogan, I I Belousov, Akef Maarouf Yassine Akef Maarouf Yassine
Expert panels of AUA and EAU defined highly effective approaches to surgical treatment of ureterolithiasis and recommended extracorporeal and contact lithotripsy as the main options. Therapeutic strategy for ureteral stones measuring less than 10 mm is clearly defined and supported by the Russian Society of Urology. At the same time, the views of researchers on the management of large ureteral stones vary. This literature review provides information on the results of extracorporeal shock-wave lithotripsy and contact ureterolithotripsy of large stones located in various parts of the ureter...
December 2016: Urologii︠a︡
https://www.readbyqxmd.com/read/28213607/efficacy-and-safety-of-nonoperative-treatment-for-acute-appendicitis-a-meta-analysis
#6
REVIEW
Roxani Georgiou, Simon Eaton, Michael P Stanton, Agostino Pierro, Nigel J Hall
CONTEXT: Nonoperative treatment (NOT) with antibiotics alone of acute uncomplicated appendicitis (AUA) in children has been proposed as an alternative to appendectomy. OBJECTIVE: To determine safety and efficacy of NOT based on current literature. DATA SOURCES: Three electronic databases. STUDY SELECTION: All articles reporting NOT for AUA in children. DATA EXTRACTION: Two reviewers independently verified study inclusion and extracted data...
March 2017: Pediatrics
https://www.readbyqxmd.com/read/28195275/bond-strengths-of-orthodontic-metal-brackets-to-tribochemically-silica-coated-zirconia-surfaces-using-different-10-methacryloyloxydecyl-dihydrogen-phosphate-containing-primers
#7
Na-Hyun Kim, Yoon-Ji Kim, Dong-Yul Lee
PURPOSE: To evaluate the effects of tribochemical silica coating and different 10-methacryloyloxydecyl dihydrogen phosphate (MDP)-containing primers on the shear bond strength (SBS) of orthodontic metal brackets to yttrium-stabilized tetragonal zirconia polycrystal (Y-TZP) surfaces. MATERIALS AND METHODS: One hundred ninety polished Y-TZP specimens were randomly assigned to 19 groups (n = 10): 30 specimens were used for surface analyses after polishing with 600-grit silicon carbide paper, airborneparticle abrasion with 50-μm alumina (A), or tribochemical silica coating (CoJet [C]); 160 specimens were used in SBS testing of orthodontic metal brackets to Y-TZP after alumina airborne-particle abrasion or tribochemical silica coating and application of either ESPE-Sil (S) (ASn, ASa, CSn, CSa), Alloy Primer (AP) (AAPn, AAPa, CAPn, CAPa), Clearfil Ceramic Primer (CP) (ACPn, ACPa, CCPn, CCPa), or Scotchbond Universal (U) (AUn, AUa, CUn, CUa) and either stored in water for 24 h (non-aged, n) or thermocycled 5000 times (aged, a)...
February 10, 2017: Journal of Adhesive Dentistry
https://www.readbyqxmd.com/read/28163030/aua-white-paper-non-neurogenic-chronic-urinary-retention-consensus-definition-treatment-algorithm-and-outcome-endpoints
#8
John T Stoffel, Andrew C Peterson, Jaspreet S Sandhu, Anne M Suskind, John T Wei, Deborah J Lightner
No abstract text is available yet for this article.
February 2, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28119778/long-term-efficacy-of-extracorporeal-shock-wave-therapy-eswt-for-treatment-of-refractory-chronic-abacterial-prostatitis
#9
Ghazi Mohammad Al Edwan, Muheilan Mustafa Muheilan, Omar Nabeeh M Atta
OBJECTIVE: To evaluate the effect and safety of extracorporeal shockwave therapy (ESWT) on chronic pelvic pain syndrome (CPPS)/chronic abacterial prostatitis after failure of most other modalities of treatment, the maintenance of the treatment effect for up to one year post treatment and whether the patients are in need for further sessions. MATERIALS AND METHODS: In a follow-up survey of 41 patients, the study inclusion criteria were CPPS patients who failed at least previously 3 modalities of treatment other than ESWT, who were treated by ESWT once a week for one month with a protocol of 2500 pulses at 1 bar over 13 min, Nonaddiction to drugs and narcotics...
February 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28101889/predictors-of-successful-trial-without-catheter-following-acute-urinary-retention-in-benign-prostatic-enlargement-a-single-centre-multivariate-analysis
#10
Ankur Bansal, Aditi Arora
OBJECTIVE: To evaluate the parameters which predict the success or failure of trial without catheter (TWOC) for acute urine retention (AUR). MATERIALS AND METHODS: Medical records of 2 188 patients presenting with first episode of AUR were analyzed. All patients underwent catheterization and were started on α-blocker followed by TWOC. Age, baseline American urological association (AUA) score, prostate volume (PV), residual volume of urine (RV) and intravesical prostatic protrusion (IPP), prostate specific antigen (PSA) were recorded...
January 19, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28086981/does-antiretroviral-treatment-change-hiv-1-codon-usage-patterns-in-its-genes-a-preliminary-bioinformatics-study
#11
Navaneethan Palanisamy, Nathan Osman, Frédéric Ohnona, Hong-Tao Xu, Bluma Brenner, Thibault Mesplède, Mark A Wainberg
BACKGROUND: Codon usage bias has been described for various organisms and is thought to contribute to the regulation of numerous biological processes including viral infections. HIV-1 codon usage has been previously shown to be different from that of other viruses and man. It is evident that the antiretroviral drugs used to restrict HIV-1 replication also select for resistance variants. We wanted to test whether codon frequencies in HIV-1 sequences from treatment-experienced patients differ from those of treatment-naive individuals due to drug pressure affecting codon usage bias...
January 7, 2017: AIDS Research and Therapy
https://www.readbyqxmd.com/read/28058776/guideline-of-guidelines-non-muscle-invasive-bladder-cancer
#12
LETTER
Solomon L Woldu, Aditya Bagrodia, Yair Lotan
Non-muscle-invasive bladder cancer (NMIBC) represents the vast majority of bladder cancer diagnoses, but this definition represents a spectrum of disease with a variable clinical course, notable for significant risk of recurrence and potential for progression. Management involves risk-adapted strategies of cystoscopic surveillance and intravesical therapy with the goal of bladder preservation when safe to do so. Multiple organizational guidelines exist to help practitioners manage this complicated disease process, but adherence to management principles among practising urologists is reportedly low...
March 2017: BJU International
https://www.readbyqxmd.com/read/28043843/outcomes-of-holmium-laser-enucleation-of-the-prostate-in-the-re-treatment-setting
#13
Tracy Marien, Mustafa Kadihasanoglu, Teerayut Tangpaitoon, Nadya York, Andrew T Blackburne, Haidar Abdul-Muhsin, Michael S Borofsky, Amy E Krambeck, Mitchell R Humphreys, James E Lingeman, Nicole L Miller
PURPOSE: Holmium laser enucleation of the prostate can also be applied in the re-treatment setting when other benign prostatic hyperplasia therapies fail. We compared outcomes in men who underwent holmium laser enucleation of the prostate in the primary vs the re-treatment setting. MATERIALS AND METHODS: We retrospectively reviewed the records of 2,242 patients who underwent holmium laser enucleation of the prostate at a total of 4 academic hospitals between 2003 and 2015...
December 30, 2016: Journal of Urology
https://www.readbyqxmd.com/read/28012747/the-american-urological-association-symptom-index-for-benign-prostatic-hyperplasia
#14
Michael J Barry, Floyd J Fowler, Michael P O'leary, Reginald C Bruskewitz, H Logan Holtgrewe, Winston K Mebust, Abraham T K Cockett
A symptom index for benign prostatic hyperplasia (BPH) was developed and validated by a multidisciplinary measurement committee of the American Urological Association (AUA). Validation studies were conducted involving a total of 210 BPH patients and 108 control subjects. The final AUA symptom index includes 7 questions covering frequency, nocturia, weak urinary stream, hesitancy, intermittence, incomplete emptying and urgency. On revalidation, the index was internally consistent (Cronbach's α = 0.86) and the score generated had excellent test-retest reliability (r = 0...
February 2017: Journal of Urology
https://www.readbyqxmd.com/read/28010967/25-years-of-experience-with-the-aua-symptom-index-increasing-recognition-that-the-bladder-is-an-unreliable-witness
#15
Christopher R Chapple
No abstract text is available yet for this article.
December 20, 2016: Journal of Urology
https://www.readbyqxmd.com/read/28006956/findings-and-impact-of-early-imaging-after-partial-nephrectomy
#16
Ryan W Tubre, William P Parker, Travis Dum, Tim Walmann, Zachary Hamilton, Moben Mirza, David A Duchene
INTRODUCTION: American Urological Association guidelines for surveillance of renal-cell carcinoma after partial nephrectomy recommend imaging within 3-12 months of surgery. Imaging following partial nephrectomy may be difficult to interpret due to the surgical defect, the use of surgical material, and normal postoperative fluid collections. Our primary objective was to evaluate the frequency of indeterminate postoperative imaging results and how those radiographic findings altered patient management...
March 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28003294/acute-uncomplicated-appendicitis-study-rationale-and-protocol-for-a-multicentre-prospective-randomised-controlled-non-inferiority-study-to-evaluate-the-safety-and-effectiveness-of-non-operative-management-in-children-with-acute-uncomplicated-appendicitis
#17
Jane Xu, Yingrui Cyril Liu, Susan Adams, Jonathan Karpelowsky
INTRODUCTION: This article presents an overview of a prospective randomised controlled non-inferiority study designed to evaluate the safety and effectiveness of non-operative management (NOM) with operative management in children with acute uncomplicated appendicitis (AUA). Here, we present the study protocol for this APRES study, a multicentre Australian study. The rationale and details of future analysis, in particular, non-inferiority calculations, cost-effectiveness, feasibility and acceptability of each intervention...
December 21, 2016: BMJ Open
https://www.readbyqxmd.com/read/27987067/prophylactic-antibiotic-treatment-following-laparoscopic-robot-assisted-radical-prostatectomy-for-the-prevention-of-catheter-associated-urinary-tract-infections-did-the-aua-guidelines-make-a-difference
#18
Miki Haifler, Yoram Mor, Zohar Dotan, Jacob Ramon, Dorit E Zilberman
We sought to evaluate the effectiveness of the American Urological Association (AUA) antibiotic prophylaxis guidelines in patients undergoing robot-assisted laparoscopic radical prostatectomy (RALP). Our prospective registry database was reviewed for all RALP cases. The following variables were evaluated: age, associated comorbidities, body mass index (BMI), total operative time, length of stay (LOS), prostate weight, pathological grade and stage. Until 11/2011, RALP patients were treated with antibiotics administered in the operating room and continued until urethral catheter removal...
December 16, 2016: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/27986530/basic-laparoscopic-skills-assessment-study-validation-and-standard-setting-among-canadian-urology-trainees
#19
Jason Y Lee, Sero Andonian, Kenneth T Pace, Ethan Grober
INTRODUCTION: As urology training programs move to a competency-based medical education model, iterative assessments with objective standards will be required. To develop a valid set of technical skills standards, we initiated a national skills assessment study focusing initially on laparoscopic skills. METHODS: Between Feb2014 and Mar2016, the basic laparoscopic skill of Canadian urology trainees and attending urologists was assessed using 4 standardized tasks from the AUA BLUS curriculum; peg transfer, pattern cutting, suturing & knot tying, vascular clip-applying...
December 13, 2016: Journal of Urology
https://www.readbyqxmd.com/read/27928972/a-meta-analysis-of-acute-use-of-alcohol-and-the-risk-of-suicide-attempt
#20
G Borges, C L Bagge, C J Cherpitel, K R Conner, R Orozco, I Rossow
BACKGROUND: No review has used a meta-analytic approach to estimate common odds ratios (ORs) for the effect of acute use of alcohol (AUA) on suicide attempts. We aim to report the results of the first meta-analysis of controlled epidemiological studies on AUA and suicide attempt. METHOD: The English-language literature on Medline, PsycINFO and Google Scholar was searched for original articles and critical review on AUA and suicide attempt (period 1996-2015). Studies had to report an OR estimate for this association...
April 2017: Psychological Medicine
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