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https://www.readbyqxmd.com/read/28226916/a-pressure-and-shear-sensing-liner-for-prosthetic-sockets
#1
Jason Wheeler, Anirban Mazumdar, Lisa Marron, Kevin Dullea, Joan Sanders, Kate Allyn, Jason Wheeler, Anirban Mazumdar, Lisa Marron, Kevin Dullea, Joan Sanders, Kate Allyn, Kevin Dullea, Joan Sanders, Kate Allyn, Anirban Mazumdar, Lisa Marron, Jason Wheeler
Interface pressures are closely related to the comfort and fit of a lower-limb prosthetic socket and clinicians and researchers are interested in monitoring these loads. In particular, shear stresses at the socket/liner interface are indicative of important fit characteristics but are difficult to measure in situ. We have developed an elastomeric liner with sixteen integrated pressure and shear sensors, along with necessary wiring and data acquisition electronics. The sensors measure three-axis pressures using optical emitter/detector pairs coupled with transparent and opaque elastomeric layers...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28208994/comparison-of-the-load-deflection-characteristics-of-aesthetic-and-conventional-super-elastic-ni-ti-orthodontic-arch-wires-in-conventional-and-metal-insert-ceramic-brackets
#2
Hosseinagha Aghili, Soghra Yassaei, Neda Joshan, Nemat Hoseini
INTRODUCTION: Coated arch wires and ceramic brackets have been introduced to improve aesthetics during orthodontic treatment. AIM: The aim of this study was to determine the effects of coating on the physical properties of aesthetic orthodontic wires. MATERIAL AND METHODS: Five round wires (0.016 inch) were obtained from each of three brands: conventional uncoated super elastic Nickel Titanium (Ni-Ti) (Rematitian Lite; Dentaurum, Ispringen, Germany), HUBIT (Teflon Coated, Korea), G&H (Epoxy Coated, Greenwood, Indiana, USA) which belonged to maxillary arch...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28207868/acetylcholine-versus-cold-pressor-testing-for-evaluation-of-coronary-endothelial-function
#3
Ahmed AlBadri, Janet Wei, Puja K Mehta, Sofy Landes, John W Petersen, R David Anderson, Bruce Samuels, Babak Azarbal, Eileen M Handberg, Quanlin Li, Margo Minissian, Chrisandra Shufelt, Carl J Pepine, C Noel Bairey Merz
BACKGROUND: Assessment of coronary endothelial function with intracoronary acetylcholine (IC-Ach) provides diagnostic and prognostic data in patients with suspected coronary microvascular dysfunction (CMD), but is often not feasible due in part to the time and expertise needed for pharmacologic mixing. Cold pressor testing (CPT) is a simple and safe stimulus useful for either invasive or non-invasive endothelial function testing and myocardial perfusion imaging but has not been specifically evaluated among symptomatic women with signs of ischemic heart disease (IHD) who have no obstructive coronary artery disease (CAD)...
2017: PloS One
https://www.readbyqxmd.com/read/28207773/local-versus-global-aortic-pulse-wave-velocity-in-early-atherosclerosis-an-animal-study-in-apoe-mice-using-ultrahigh-field-mri
#4
Alexander Gotschy, Wolfgang R Bauer, Patrick Winter, Peter Nordbeck, Eberhard Rommel, Peter M Jakob, Volker Herold
Increased aortic stiffness is known to be associated with atherosclerosis and has a predictive value for cardiovascular events. This study aims to investigate the local distribution of early arterial stiffening due to initial atherosclerotic lesions. Therefore, global and local pulse wave velocity (PWV) were measured in ApoE-/- and wild type (WT) mice using ultrahigh field MRI. For quantification of global aortic stiffness, a new multi-point transit-time (TT) method was implemented and validated to determine the global PWV in the murine aorta...
2017: PloS One
https://www.readbyqxmd.com/read/28202246/analysis-of-myocardial-perfusion-parameters-in-an-ex-vivo-porcine-heart-model-using-third-generation-dual-source-ct
#5
Gert Jan Pelgrim, Taylor M Duguay, J Marco A Stijnen, Akos Varga-Szemes, Sjoerd Van Tuijl, U Joseph Schoepf, Matthijs Oudkerk, Rozemarijn Vliegenthart
PURPOSE: To evaluate the relationship between fractional flow reserve (FFR)-determined coronary artery stenosis severity and myocardial perfusion parameters derived from dynamic myocardial CT perfusion imaging (CTP) in an ex-vivo porcine heart model. METHODS: Six porcine hearts were perfused according to Langendorff. Circulatory parameters such as arterial blood flow (ABF) (L/min), mean arterial pressure (MAP) (mmHg) and heart rate (bpm) were monitored. Using an inflatable cuff and monitored via a pressure wire, coronary artery stenoses of different FFR grades were created (no stenosis, FFR = 0...
February 3, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28198106/in-vitro-microfluidic-models-of-tumor-microenvironment-to-screen-transport-of-drugs-and-nanoparticles
#6
REVIEW
Altug Ozcelikkale, Hye-Ran Moon, Michael Linnes, Bumsoo Han
Advances in nanotechnology have enabled numerous types of nanoparticles (NPs) to improve drug delivery to tumors. While many NP systems have been proposed, their clinical translation has been less than anticipated primarily due to failure of current preclinical evaluation techniques to adequately model the complex interactions between the NP and physiological barriers of tumor microenvironment. This review focuses on microfluidic tumor models for characterization of delivery efficacy and toxicity of cancer nanomedicine...
February 14, 2017: Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology
https://www.readbyqxmd.com/read/28190566/effects-of-wireless-packet-loss-in-industrial-process-control-systems
#7
Yongkang Liu, Richard Candell, Nader Moayeri
Timely and reliable sensing and actuation control are essential in networked control. This depends on not only the precision/quality of the sensors and actuators used but also on how well the communications links between the field instruments and the controller have been designed. Wireless networking offers simple deployment, reconfigurability, scalability, and reduced operational expenditure, and is easier to upgrade than wired solutions. However, the adoption of wireless networking has been slow in industrial process control due to the stochastic and less than 100% reliable nature of wireless communications and lack of a model to evaluate the effects of such communications imperfections on the overall control performance...
February 9, 2017: ISA Transactions
https://www.readbyqxmd.com/read/28185992/lasso-plate-an-original-implant-for-fixation-of-type-i-and-ii-regan-morrey-coronoid-fractures
#8
Pengfei Wang, Yan Zhuang, Zhong Li, Wei Wei, Yahui Fu, Xing Wei, Kun Zhang
INTRODUCTION: Coronoid fractures are notoriously difficult to manage particularly when there is a small fragment. We report a retrospective analysis of our experience with consecutive type I and II Regan-Morrey coronoid fractures using a lasso plate. HYPOTHESIS: Type I and II Regan-Morrey coronoid fractures can be effectively managed using a lasso plate. METHODS: From October, 2011 and December, 2013, 25 patients(21 males and 4 females, mean age 40...
February 6, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28168942/validating-the-factor-structure-and-testing-measurement-invariance-of-modified-short-form-mcgill-pain-questionnaire-ortho-sf-mpq-for-orthodontic-pain-assessment
#9
Satpal S Sandhu
OBJECTIVE: To validate the factor structure of recently modified Short-Form McGill Pain Questionnaire (Ortho-SF-MPQ) to assess orthodontic pain; and to test its Measurement Invariance (MI) across gender. METHODS: 180 orthodontic patients were enrolled in this study. 0.016 inch Super-elastic NiTi arch wire was used in 0.022″ × 0.028″ slot pre-adjusted edgewise appliance. After initial arch wire placement, pain was assessed at T1 (24 hours), T2 (day 3), and T3 (day 7) by using the Ortho-SF-MPQ which consists of seven sensory (pressure, sore, aching, tight, throbbing, pulling, miserable) and four affective (uncomfortable, strange, frustrating, annoying) descriptors...
February 7, 2017: Journal of Orthodontics
https://www.readbyqxmd.com/read/28161129/navvus-ffr-to-reduce-contrast-cost-and-radiation-contract-insights-from-a-single-centre-clinical-and-economical-evaluation-with-the-rxi-rapid-exchange-ffr-device
#10
Kaneshka Masdjedi, Nicolas M Van Mieghem, Roberto Diletti, Robert-Jan van Geuns, Peter de Jaegere, Evelyn Regar, Felix Zijlstra, Ron T van Domburg, Joost Daemen
OBJECTIVES: To assess whether the RXi Navvus system compared to the use of standard Fractional Flow Reserve (FFR) wires reduces total contrast volume, radiation and overall study cost in a real world patient population referred for coronary angiography or percutaneous coronary intervention. BACKGROUND: FFR is the mainstay of functional hemodynamic assessment of coronary artery lesions. The RXi Navvus system (ACIST Medical Systems, Eden Prairie, MN) is a monorail microcatheter with FFR-measurement capability through optical pressure sensor technology...
January 4, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28154161/development-of-coronary-pulse-wave-velocity-new-pathophysiological-insight-into-coronary-artery-disease
#11
Brahim Harbaoui, Pierre-Yves Courand, Andrei Cividjian, Pierre Lantelme
BACKGROUND: Although aortic stiffness assessed by pulse wave velocity (PWV) is a strong predictor of coronary artery disease, the significance of local coronary stiffness has never been tackled. The first objective of this study was to describe a method of measuring coronary PWV (CoPWV) invasively and to describe its determinants. The second objective was to assess both CoPWV and aortic PWV in patients presenting with acute coronary syndromes or stable coronary artery disease. METHODS AND RESULTS: In 53 patients, CoPWV was measured from the delay in pressure wave and distance traveled as a pressure wire was withdrawn from the distal to the proximal coronary segment...
February 2, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28144897/a-miniaturized-linear-wire-ion-trap-with-electron-ionization-and-single-photon-ionization-sources
#12
Qinghao Wu, Yuan Tian, Ailin Li, Derek Andrews, Aaron R Hawkins, Daniel E Austin
A linear wire ion trap (LWIT) with both electron ionization (EI) and single photon ionization (SPI) sources was built. The SPI was provided by a vacuum ultraviolet (VUV) lamp with the ability to softly ionize organic compounds. The VUV lamp was driven by a pulse amplifier, which was controlled by a pulse generator, to avoid the detection of photons during ion detection. Sample gas was introduced through a leak valve, and the pressure in the system is shown to affect the signal-to-noise ratio and resolving power...
January 31, 2017: Journal of the American Society for Mass Spectrometry
https://www.readbyqxmd.com/read/28098192/wearable-atmospheric-pressure-plasma-fabrics-produced-by-knitting-flexible-wire-electrodes-for-the-decontamination-of-chemical-warfare-agents
#13
Heesoo Jung, Jin Ah Seo, Seungki Choi
One of the key reasons for the limited use of atmospheric pressure plasma (APP) is its inability to treat non-flat, three-dimensional (3D) surface structures, such as electronic devices and the human body, because of the rigid electrode structure required. In this study, a new APP system design-wearable APP (WAPP)-that utilizes a knitting technique to assemble flexible co-axial wire electrodes into a large-area plasma fabric is presented. The WAPP device operates in ambient air with a fully enclosed power electrode and grounded outer electrode...
January 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28086778/diabetes-does-not-impact-the-diagnostic-performance-of-contrast-based-fractional-flow-reserve-insights-from-the-contrast-study
#14
Giuseppe Gargiulo, Eugenio Stabile, Marco Ferrone, Emanuele Barbato, Frederik M Zimmermann, Julien Adjedj, Barry Hennigan, Mitsuaki Matsumura, Nils P Johnson, William F Fearon, Allen Jeremias, Bruno Trimarco, Giovanni Esposito
BACKGROUND: Adenosine-free coronary pressure wire metrics have been proposed to test the functional significance of coronary artery lesions, but it is unexplored whether their diagnostic performance might be altered in patients with diabetes. METHODS: We performed a post-hoc analysis of the CONTRAST study, which prospectively enrolled an international cohort of patients undergoing routine fractional flow reserve (FFR) assessment for standard indications. Paired, repeated measurements of all physiology metrics (Pd/Pa, iFR, contrast-based FFR, and FFR) were made...
January 13, 2017: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/28067615/intracranial-atherosclerosis-from-anatomy-to-pathophysiology
#15
Yuehua Pu, Linfang Lan, Xinyi Leng, Lawrence Ks Wong, Liping Liu
Background Intracranial atherosclerotic stenosis is an important etiology subtype of ischemic stroke. Stenosis severity was thought to be the main reference index for clinical treatment and research. However, stenosis could not reflect the ischemia risk completely, instead the hemodynamic state across the lesion, the extent of collateral circulation, and perfusion impairment downstream the stenosis are more important. Aims We write this review aimed to summarize novel angiographic methods applied in the evaluation of functional severity of ICAS, and commented on their limitations and prospects in future research...
January 1, 2017: International Journal of Stroke: Official Journal of the International Stroke Society
https://www.readbyqxmd.com/read/28067444/irreversible-conversion-of-a-water-ethanol-solution-into-an-organized-two-dimensional-network-of-alternating-supramolecular-units-in-a-hydrophobic-zeolite-under-pressure
#16
Rossella Arletti, Ettore Fois, Lara Gigli, Giovanna Vezzalini, Simona Quartieri, Gloria Tabacchi
Turning disorder into organization is a key issue in science. By making use of X-ray powder diffraction and modeling studies, we show herein that high pressures in combination with the shape and space constraints of the hydrophobic all-silica zeolite ferrierite separate an ethanol-water liquid mixture into ethanol dimer wires and water tetramer squares. The confined supramolecular blocks alternate in a binary two-dimensional (2D) architecture that remains stable upon complete pressure release. These results support the combined use of high pressures and porous networks as a viable strategy for driving the organization of molecules or nano-objects towards complex, pre-defined patterns relevant for the realization of novel functional nanocomposites...
January 9, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28060842/suburothelial-bladder-contraction-detection-with-implanted-pressure-sensor
#17
Steve J A Majerus, Paul C Fletter, Elizabeth K Ferry, Hui Zhu, Kenneth J Gustafson, Margot S Damaser
AIMS: Managing bladder pressure in patients with neurogenic bladders is needed to improve rehabilitation options, avoid upper tract damage, incontinence, and their associated co-morbidities and mortality. Current methods of determining bladder contractions are not amenable to chronic or ambulatory settings. In this study we evaluated detection of bladder contractions using a novel piezoelectric catheter-free pressure sensor placed in a suburothelial bladder location in animals. METHODS: Wired prototypes of the pressure monitor were implanted into 2 nonsurvival (feline and canine) and one 13-day survival (canine) animal...
2017: PloS One
https://www.readbyqxmd.com/read/28026109/soft-elastomers-with-ionic-liquid-filled-cavities-as-strain-isolating-substrates-for-wearable-electronics
#18
Yinji Ma, Matt Pharr, Liang Wang, Jeonghyun Kim, Yuhao Liu, Yeguang Xue, Rui Ning, Xiufeng Wang, Ha Uk Chung, Xue Feng, John A Rogers, Yonggang Huang
Managing the mechanical mismatch between hard semiconductor components and soft biological tissues represents a key challenge in the development of advanced forms of wearable electronic devices. An ultralow modulus material or a liquid that surrounds the electronics and resides in a thin elastomeric shell provides a strain-isolation effect that enhances not only the wearability but also the range of stretchability in suitably designed devices. The results presented here build on these concepts by (1) replacing traditional liquids explored in the past, which have some nonnegligible vapor pressure and finite permeability through the encapsulating elastomers, with ionic liquids to eliminate any possibility for leakage or evaporation, and (2) positioning the liquid between the electronics and the skin, within an enclosed, elastomeric microfluidic space, but not in direct contact with the active elements of the system, to avoid any negative consequences on electronic performance...
December 27, 2016: Small
https://www.readbyqxmd.com/read/27974668/importance-of-adjunct-delivery-techniques-to-optimize-deployment-success-of-distal-protection-filters-during-vein-graft-intervention
#19
Antony G Kaliyadan, Harnish Chawla, David L Fischman, Nicholas Ruggiero, Michael Gannon, Paul Walinsky, Michael P Savage
OBJECTIVES: This study assessed the impact of adjunct delivery techniques on the deployment success of distal protection filters in saphenous vein grafts (SVGs). BACKGROUND: Despite their proven clinical benefit, distal protection devices are underutilized in SVG interventions. Deployment of distal protection filters can be technically challenging in the presence of complex anatomy. Techniques that facilitate the delivery success of these devices could potentially improve clinical outcomes and promote greater use of distal protection...
February 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/27956409/functional-assessment-of-coronary-artery-disease-using-whole-heart-dynamic-computed-tomographic-perfusion
#20
Logan Hubbard, Benjamin Ziemer, Jerry Lipinski, Bahman Sadeghi, Hanna Javan, Elliott M Groves, Shant Malkasian, Sabee Molloi
BACKGROUND: Computed tomographic (CT) angiography is an important tool for the evaluation of coronary artery disease but often correlates poorly with myocardial ischemia. Current dynamic CT perfusion techniques can assess ischemia but have limited accuracy and deliver high radiation dose. Therefore, an accurate, low-dose, dynamic CT perfusion technique is needed. METHODS AND RESULTS: A total of 20 contrast-enhanced CT volume scans were acquired in 5 swine (40±10 kg) to generate CT angiography and perfusion images...
December 2016: Circulation. Cardiovascular Imaging
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