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https://www.readbyqxmd.com/read/29191346/neutrophilic-dermatoses-kids-are-not-just-little-people
#1
Grace L Lee, Amy Y-Y Chen
Neutrophilic dermatoses are a group of inflammatory skin disorders characterized by an overactive innate immune system with dysregulation of neutrophils without underlying infectious etiology. The major representative conditions discussed are Sweet syndrome; pyoderma gangrenosum; neutrophilic eccrine hidradenitis; palmoplantar eccrine hidradenitis; subcorneal pustular dermatoses; bowel-associated dermatosis arthritis syndrome; and synovitis, acne, pustulosis, hyperostosis, and osteitis. We will also discuss other neutrophilic conditions present almost exclusively in the pediatric population, including congenital erosive and vesicular dermatosis with reticulated supple scarring and the recently described group of autoinflammatory diseases...
November 2017: Clinics in Dermatology
https://www.readbyqxmd.com/read/29184806/polycystic-ovary-syndrome-in-adolescence-diagnostic-and-therapeutic-strategies
#2
REVIEW
Manmohan K Kamboj, Andrea E Bonny
Controversy continues about the underlying etiopathogenesis, diagnostic criteria, and recommendations for polycystic ovary syndrome (PCOS) in adolescents. Recent literature has recognized these deficiencies and evidence based expert recommendations have become more available. The purpose of this chapter is to offer primary care providers a practical understanding and approach to the diagnosis and treatment of PCOS in adolescents. Although the presence of polycystic ovary morphology (PCOM) is included as a key diagnostic criterion of PCOS in adults, it is currently not recommended for the diagnosis in adolescents...
October 2017: Translational pediatrics
https://www.readbyqxmd.com/read/29180907/clinical-behavior-of-a-cohort-of-adult-women-with-facial-acne-treated-with-combined-oral-contraceptive-ethinylestradiol-20-%C3%A2%C2%B5g-dienogest-2-mg
#3
John Palacio-Cardona, Diana María Caicedo Borrero
Acne vulgaris is the most common skin disease. It affects the young adult female population and generates great impact on physical and mental health. One of the treatments with good results for affected women is combined oral contraceptive pills (COCPs). The aim of this study was to determine the clinical effect of facial acne management with ethinylestradiol 20 µg/dienogest 2 mg in a cohort of Colombian adult women. A cohort of 120 female university students was followed for 12 months. These participants were enrolled in the Sexual and Reproductive Health Program of the Santiago de Cali University...
2017: International Journal of Women's Health
https://www.readbyqxmd.com/read/29178982/microbiology-and-associated-risk-factors-in-alloplastic-total-joint-infections-a-20-year-retrospective-study
#4
Rhae Riegel, Kevin Sweeney, Gino Inverso, Peter Quinn, Eric J Granquist
PURPOSE: Prosthetic joint infection (PJI) is a rare complication of temporomandibular joint replacement (TJR). This study evaluated TJR PJIs at the authors' institution over a 20-year period, including micro-organisms cultured, antibiotic resistance patterns, and intraoperative protocols of TJR. PATIENTS AND METHODS: Patients were identified using Current Procedural Terminology and International Classification of Diseases, Ninth Revision codes and surgical logs from January 1995 through 2015...
November 8, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29177119/diversity-of-bacterial-communities-on-the-facial-skin-of-different-age-group-thai-males
#5
Alisa Wilantho, Pamornya Deekaew, Chutika Srisuttiyakorn, Sissades Tongsima, Naraporn Somboonna
Background: Skin microbiome varies from person to person due to a combination of various factors, including age, biogeography, sex, cosmetics and genetics. Many skin disorders appear to be related to the resident microflora, yet databases of facial skin microbiome of many biogeographies, including Thai, are limited. Methods: Metagenomics derived B-RISA and 16S rRNA gene sequencing was utilized to identify the culture-independent bacterial diversity on Thai male faces (cheek and forehead areas)...
2017: PeerJ
https://www.readbyqxmd.com/read/29171399/afast-an-adult-female-acne-treatment-algorithm-for-daily-clinical-practice
#6
Florence Poli, Nicole Auffret, Jean Paul Claudel, Marie-Thérèse Leccia, Brigitte Dreno
No abstract text is available yet for this article.
November 24, 2017: European Journal of Dermatology: EJD
https://www.readbyqxmd.com/read/29131127/pleiotropic-effects-of-white-willow-bark-and-1-2-decanediol-on-human-adult-keratinocytes
#7
Eleonora Bassino, Franco Gasparri, Luca Munaron
BACKGROUND: Acne vulgaris is a common skin defect, usually occurring during adolescence, but often it can persist in adults leaving permanent face scarring. Acne is usually treated with topical drugs, oral antibiotics, retinoids, and hormonal therapies, but medicinal plants are increasingly employed. OBJECTIVE: To investigate the protective role of white willow bark (WWB) and 1,2-decanediol (DD) on the damage caused by lipopolysaccharides (LPS) on human adult keratinocytes (HaCaT)...
November 8, 2017: Skin Pharmacology and Physiology
https://www.readbyqxmd.com/read/29036256/pharmacokinetic-comparison-of-once-daily-topical-minocycline-foam-4-vs-oral-minocycline-for-moderate-to-severe-acne
#8
Terry M Jones, Herman Ellman, Tina deVries
OBJECTIVE: To characterize minocycline pharmacokinetics and relative bioavailability following multiple-dose topical administration of minocycline hydrochloride (HCl) foam 4% (FMX101 4%) as compared with single-dose oral administration of minocycline HCl extended-release tablets (Solodyn®) in subjects with moderate-to-severe acne. METHODS: A Phase 1, single-center, nonrandomized, open-label, active-controlled, 2-period, 2-treatment crossover clinical study. The study included 30 healthy adults (mean age, 22...
October 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29029907/acne-sexual-orientation-and-mental-health-among-young-adults-in-the-united-states-a-population-based-cross-sectional-study
#9
Yi Gao, Esther K Wei, Sarah T Arron, Eleni Linos, David J Margolis, Matthew D Mansh
No abstract text is available yet for this article.
November 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29024079/the-preadolescent-acne-microbiome-a-prospective-randomized-pilot-study-investigating-characterization-and-effects-of-acne-therapy
#10
Carrie C Coughlin, Shane M Swink, Joseph Horwinski, Georgia Sfyroera, Julia Bugayev, Elizabeth A Grice, Albert C Yan
BACKGROUND/OBJECTIVES: Acne, a common pediatric disease, tends to be more comedonal in preadolescents, whereas older individuals are more likely to have inflammatory lesions in addition to comedones. Thus the microbiome of preadolescents may be different. In this pilot study we aimed to characterize the preadolescent acne microbiome, compare the microbiome in preadolescents with and without acne, and investigate changes in the microbiome after topical treatment with benzoyl peroxide or a retinoid in a small cohort of preadolescents...
October 11, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/29024049/a-cross-sectional-study-of-the-perceptions-about-triggering-factors-in-acne-patients
#11
Clio Dessinioti, Eftychia Platsidaki, Chrisa Zisimou, Vasiliki Tzanetakou, Andreas Katsambas, Christina Antoniou
Acne is a common, inflammatory skin disease of the pilosebaceous unit.(1) Patients often have misconceptions about factors exacerbating acne that may influence their treatment seeking behavior. We conducted a cross-sectional study to investigate the perceptions of patients with acne about triggering factors, and how they may differ among adults and adolescents. This article is protected by copyright. All rights reserved.
October 10, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28990222/managing-acne-in-the-middle-east-consensus-recommendations
#12
REVIEW
H Gollnick, A A Abanmi, M Al-Enezi, A Al Hammadi, I Galadari, A-G Kibbi, S Zimmo
Acne has been estimated to affect the majority of people at some point in their life and is common in Middle Eastern countries. While acne is frequently perceived to be a self-limited disease of adolescence, there is an increasing population of adults with acne. Information about the management of acne in the Middle East is somewhat sparse; however, several studies have recently been conducted and will be discussed in this supplement.
November 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28979696/effects-of-acrylonitrile-induced-oxidative-stress-on-testicular-apoptosis-through-activation-of-nf-%C3%AE%C2%BAb-signaling-pathway-in-male-sprague-dawley-rats
#13
Yuhui Dang, Qianlong Zhao, Boyan Luo, Li Pan, Qian Wei, Ruiping Zhang, Qiaorong Fan, Junyi Chen, Ruixia Chang, Jie Zhang, Zhilan Li
Acrylonitrile (ACN) treatment can induce testicular toxicity in Sprague-Dawley (SD) rats, with the toxicity potentially related to apoptosis, mediated by nuclear factor-κB (NF-κB). The present study investigated the potential role of NF-κB in the induction of apoptosis and testicular toxicity in ACN-treated rats. Adult male SD rats were randomly divided into 3 treatment groups: a control group (corn oil), an ACN group (50 mg/kg) in which ACN was administered by gavage, and an ACN and N-acetylcysteine (ACN+NAC) group...
2017: American Journal of Translational Research
https://www.readbyqxmd.com/read/28972874/impact-of-sequential-culture-results-on-diagnosis-and-de-escalation-of-the-antibiotic-regimen-in-joint-and-bone-infections
#14
Solen Kernéis, Cécile Leprince, Denis Archambeau, Luc Eyrolle, Philippe Leclerc, Hélène Poupet, Julien Loubinoux, Rémy Gauzit, Dominique Salmon, Odile Launay, Claire Poyart, Philippe Anract, Philippe C Morand
BACKGROUND: According to existing guidelines, orthopedic specimens collected in joint and bone infections (JBI) in our institution are cultured on several media sets and incubated for two, seven, and 14 days. The optimal timing for de-escalation of the first-line antibiotic combination according to the culture results needs to be defined. METHODS: Single-center, retrospective analysis of all adult patients with a first documented episode of JBI between May 2012 and April 2013...
November 2017: Surgical Infections
https://www.readbyqxmd.com/read/28915843/protective-effects-of-gaba-against-metabolic-and-reproductive-disturbances-in-letrozole-induced-polycystic-ovarian-syndrome-in-rats
#15
Asad Ullah, Sarwat Jahan, Suhail Razak, Madeeha Pirzada, Hizb Ullah, Ali Almajwal, Naveed Rauf, Tayyaba Afsar
BACKGROUND: PCOs is a heterogeneous disorder with anovulation/oligo ovulation usually taken as oligo menorrhoea or amenorrhoea, hyperandrogenemia, hirsutism, acne, androgen alopecia and polycystic ovaries as the key diagnostic feathers. The study was undertaken to investigate the possible protective and ameliorating effects of GABA in Letrozole induced PCOS model in rats by targeting insulin resistance. METHODS: PCOs in Adult female rat was induced by the daily gastric administration of letrozole (1 mg/kg/day) in CMC (0...
September 15, 2017: Journal of Ovarian Research
https://www.readbyqxmd.com/read/28912911/doxycycline-induced-acute-pancreatitis-a-rare-adverse-event
#16
Prashanth Rawla, Jeffrey Pradeep Raj
Doxycycline is a broad-spectrum antibiotic belonging to the tetracycline group which acts by inhibiting bacterial protein synthesis. It is considered to be a relatively safe drug. We report a case of doxycycline-induced acute pancreatitis (DIAP) in an adult female patient who was started on the usual therapeutic dose 1 week before for acne vulgaris. The WHO causality assessment was possible, and the Naranjo scale confirmed it as "definite" adverse drug reaction. A brief literature review on case reports previously reporting DIAP has also been summarized...
August 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/28873105/hair-and-scalp-disorders-in-adult-and-pediatric-patients-with-skin-of-color
#17
Susan C Taylor, Victoria Barbosa, Cheryl Burgess, Candrice Heath, Amy J McMichael, Temitayo Ogunleye, Valerie Callender
As increasing numbers of patients of African descent seek treatment for hair and scalp-related diseases, it is imperative that all dermatologists be adequately trained to address the concerns of this patient population. We present must-know information to effectively approach the concerns of patients with seborrheic dermatitis, acquired trichorrhexis nodosa, acne keloidalis nuchae, pseudofolliculitis barbae, alopecia, and common pediatric hair and scalp disorders.
July 2017: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/28862134/adult-female-acne-treated-with-spironolactone-a-retrospective-data-review-of-70-cases
#18
Anne Isvy-Joubert, Jean-Michel Nguyen, Aurélie Gaultier, Mélanie Saint-Jean, Marie Le Moigne, Elodie Boisrobert, Amir Khammari, Brigitte Dreno
The prevalence of acne in the adult population is increasing, particularly in women. Spironolactone regulates sebaceous gland activity by blocking androgen receptor. To evaluate retrospectively the efficacy of spironolactone in women with acne. Data from 70 women of at least 20 years, treated for their acne between 2010 and 2015 with low-dose spironolactone (≤150 mg/day), were analysed. Remission was defined by the number of retentional lesions inferior or equal to five and inflammatory lesions inferior or equal to two on the face...
August 1, 2017: European Journal of Dermatology: EJD
https://www.readbyqxmd.com/read/28768538/pulsed-radiofrequency-or-anterior-neurectomy-for-anterior-cutaneous-nerve-entrapment-syndrome-acnes-the-pulse-trial-study-protocol-of-a-randomized-controlled-trial
#19
Robbert C Maatman, Monique A H Steegers, Oliver B A Boelens, Toine C Lim, Hans J van den Berg, Sandra A S van den Heuvel, Marc R M Scheltinga, Rudi M H Roumen
BACKGROUND: Some patients with chronic abdominal pain suffer from an anterior cutaneous nerve entrapment syndrome (ACNES). This somewhat illusive syndrome is thought to be caused by the entrapment of end branches of the intercostal nerves residing in the abdominal wall. If ACNES is suspected, a local injection of an anesthetic agent may offer relief. If pain is recurrent following multiple-injection therapy, an anterior neurectomy entailing removal of the entrapped nerve endings may be considered...
August 2, 2017: Trials
https://www.readbyqxmd.com/read/28707712/acne-prevalence-and-associations-with-lifestyle-a-cross-sectional-online-survey-of-adolescents-young-adults-in-7-european-countries
#20
P Wolkenstein, A Machovcová, J C Szepietowski, D Tennstedt, S Veraldi, A Delarue
BACKGROUND: Although acne vulgaris is a common skin disorder, limited epidemiological data exist specifically for European populations. OBJECTIVE: To determine the prevalence of self-reported acne among young people in Europe and evaluate the effect of lifestyle on acne. METHODS: We conducted a cross-sectional population-based online survey in representative samples of individuals aged 15-24 years in Belgium, Czech and Slovak Republics, France, Italy, Poland and Spain (n=10,521), identified by a quota sampling method based on age, geographic location, and socio-professional category...
July 14, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
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