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https://www.readbyqxmd.com/read/28431313/raman-spectroscopy-for-the-characterization-of-different-fractions-of-hemp-essential-oil-extracted-at-130%C3%A2-c-using-steam-distillation-method
#1
Muhammad Asif Hanif, Haq Nawaz, Saima Naz, Rubina Mukhtar, Nosheen Rashid, Ijaz Ahmad Bhatti, Muhammad Saleem
In this study, Raman spectroscopy along with Principal Component Analysis (PCA) is used for the characterization of pure essential oil (pure EO) isolated from the leaves of the Hemp (Cannabis sativa L.,) as well as its different fractions obtained by fractional distillation process. Raman spectra of pure Hemp essential oil and its different fractions show characteristic key bands of main volatile terpenes and terpenoids, which significantly differentiate them from each other. These bands provide information about the chemical composition of sample under investigation and hence can be used as Raman spectral markers for the qualitative monitoring of the pure EO and different fractions containing different active compounds...
April 1, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28397674/-self-medication-with-cannabidiol-oil-in-a-patient-with-primary-lateral-sclerosis
#2
Merete Karlsborg, Anette Kvindebjerg Christophersen, Caroline Pontoppidan, Jens Peter Kampmann
Many patients with neurological disorders have symptoms which are difficult to treat with conventional medication. In this case report we present a 40-year-old male patient with primary lateral sclerosis who used cannabidiol oil as therapy. We discuss the evidence of the effects of cannabidiol in the treatment of patients with neurological disease, and we raise the question: "Should patients who use illegal cannabis products as self-medication be diagnosed as drug abusers?"
February 13, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28355118/carbonyl-compounds-produced-by-vaporizing-cannabis-oil-thinning-agents
#3
William D Troutt, Matthew D DiDonato
OBJECTIVE: Cannabis use has increased in the United States, particularly the use of vaporized cannabis oil, which is often mixed with thinning agents for use in vaporizing devices. E-cigarette research shows that heated thinning agents produce potentially harmful carbonyls; however, similar studies have not been conducted (1) with agents that are commonly used in the cannabis industry and (2) at temperatures that are appropriate for cannabis oil vaporization. The goal of this study was to determine whether thinning agents used in the cannabis industry produce potentially harmful carbonyls when heated to a temperature that is appropriate for cannabis oil vaporization...
March 29, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28323498/predictors-of-adult-e-cigarette-users-vaporizing-cannabis-using-e-cigarettes-and-vape-pens
#4
Meghan E Morean, Noah Lipshie, Margo Josephson, Dawn Foster
BACKGROUND: Given limited extant research, we assessed the use of portable, battery-powered cannabis vaporizers by adult e-cigarette users. METHODS: 522 adult vapers completed an online survey. Demographics; lifetime and past-month cannabis vaporization via e-cigarettes/vape-pens; preferences for hash oil, D-9-tetrahydrocannabinol (THC) wax, or dried buds; and cannabis vaporization beliefs and motives were examined. Demographics, age of e-cigarette onset, e-cigarette use frequency, state-level legal status of cannabis, cannabis vaping beliefs/motives, and impulsivity were examined as predictors of lifetime cannabis vaporization, past-month cannabis vaporization, and cannabis vaping frequency...
March 21, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28263690/psychiatric-complications-of-cannabis-oil-use-in-cancer-patients-whose-responsibility-is-it-to-manage
#5
Raymond C Parrish, Hermioni N Lokko, David P Yuppa, Ilana M Braun, Fremonta L Meyer
No abstract text is available yet for this article.
March 6, 2017: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/28248584/-tree-in-bloom-severe-acute-lung-injury-induced-by-vaping-cannabis-oil
#6
Tao He, Margarita Oks, Michael Esposito, Harry Steinberg, Mina Makaryus
No abstract text is available yet for this article.
March 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28240903/flexible-bionanocomposites-from-epoxidized-hemp-seed-oil-thermosetting-resin-reinforced-with-halloysite-nanotubes
#7
Peter S Shuttleworth, Ana M Díez-Pascual, Carlos Marco, Gary Ellis
Hemp seed (Cannabis sativa L.) oil comprises a variety of beneficial unsaturated triglycerides with well-documented nutritional and health benefits. However, it can become rancid over a relatively short time period, leading to increased industrial costs and waste of a valuable product. The development of sustainable polymers is presented as a strategy, where both the presence of unsaturation and peroxide content could be effectively used to alleviate both the waste and financial burden. After the reaction with peroxyacetic acid, the incorporation of halloysite nanotubes (HNTs), and the subsequent thermal curing, without the need for organic solvents or interfacial modifiers, flexible transparent materials with a low glass-transition temperature were developed...
March 8, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28207408/evaluation-of-cannabinoids-concentration-and-stability-in-standardized-preparations-of-cannabis-tea-and-cannabis-oil-by-ultra-high-performance-liquid-chromatography-tandem-mass-spectrometry
#8
Roberta Pacifici, Emilia Marchei, Francesco Salvatore, Luca Guandalini, Francesco Paolo Busardò, Simona Pichini
BACKGROUND: Cannabis has been used since ancient times to relieve neuropathic pain, to lower intraocular pressure, to increase appetite and finally to decrease nausea and vomiting. The combination of the psychoactive cannabis alkaloid Δ9-tetrahydrocannabinol (THC) with the non-psychotropic alkaloids cannabidiol (CBD) and cannabinol (CBN) demonstrated a higher activity than THC alone. The Italian National Institute of Health sought to establish conditions and indications on how to correctly use nationally produced cannabis to guarantee therapeutic continuity in individuals treated with medical cannabis...
February 16, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/28191338/accelerated-burn-wound-closure-in-mice-with-a-new-formula-based-on-traditional-medicine
#9
Mehrnaz Mehrabani, Seyyed Mohsen Seyyedkazemi, Mohammad Hadi Nematollahi, Elham Jafari, Mitra Mehrabani, Mohammad Mehdipour, Zahra Sheikhshoaee, Ali Mandegary
BACKGROUND: A combination of the oils of sesame, hemp, wild pistachio, and walnut has been used for treatment of skin disorders, including wound burns, in some parts of Kerman, Iran. Evaluation of this remedy in the form of a pharmaceutical formulation in animal models can pave the way for its future application in wound burn healing in humans. OBJECTIVES: This experimental study investigated the healing potential of a new formula (NF) based on folk medicine from Iran for the treatment of third degree burns in mice...
November 2016: Iranian Red Crescent Medical Journal
https://www.readbyqxmd.com/read/28188639/effect-of-unconventional-oilseeds-safflower-poppy-hemp-camelina-on-in-vitro-ruminal-methane-production-and-fermentation
#10
Shaopu Wang, Michael Kreuzer, Ueli Braun, Angela Schwarm
BACKGROUND: Dietary supplementation with oilseeds can reduce methane emission in ruminants, but only a few common seeds have been tested so far. This study tested safflower (Carthamus tinctorius), poppy (Papaver somniferum), hemp (Cannabis sativa), and camelina (Camelina sativa) seeds in vitro using coconut (Cocos nucifera) oil and linseed (Linum usitatissimum) as positive controls. RESULTS: All the tested oilseeds suppressed methane yield (ml g(-1) dry matter, up to 21%) compared to the non-supplemented control when provided at 70 g oil kg(-1) dry matter, and they were as effective as coconut oil...
February 11, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28050136/a-user-s-guide-to-cannabinoid-therapies-in-oncology
#11
REVIEW
V Maida, P J Daeninck
"Cannabinoid" is the collective term for a group of chemical compounds that either are derived from the Cannabis plant, are synthetic analogues, or occur endogenously. Although cannabinoids interact mostly at the level of the currently recognized cannabinoid receptors, they might have cross reactivity, such as at opioid receptors. Patients with malignant disease represent a cohort within health care that have some of the greatest unmet needs despite the availability of a plethora of guideline-driven disease-modulating treatments and pain and symptom management options...
December 2016: Current Oncology
https://www.readbyqxmd.com/read/27904421/cannabis-induced-moto-cognitive-dysfunction-in-wistar-rats-ameliorative-efficacy-of-nigella-sativa
#12
Aminu Imam, Moyosore Saliu Ajao, Abdulbasit Amin, Wahab Imam Abdulmajeed, Abdulmumin Ibrahim, Olayemi Joseph Olajide, Musa Iyiola Ajibola, Abdulmusawir Alli-Oluwafuyi, Wasiu Gbolahan Balogun
BACKGROUND: Cannabis is a widely used illicit drug with various threats of personality syndrome, and Nigella sativa has been widely implicated as having therapeutic efficacy in many neurological diseases. The present study investigates the ameliorative efficacy of Nigella sativa oil (NSO) on cannabis-induced moto-cognitive defects. METHODS: Scopolamine (1 mg/kg i.p.) was given to induce dementia as a standard base line for cannabis (20 mg/kg)-induced cognitive impairment, followed by an oral administration of NSO (1 ml/kg) for 14 consecutive days...
September 2016: Malaysian Journal of Medical Sciences: MJMS
https://www.readbyqxmd.com/read/27757083/an-orally-active-cannabis-extract-with-high-content-in-cannabidiol-attenuates-chemically-induced-intestinal-inflammation-and-hypermotility-in-the-mouse
#13
Ester Pagano, Raffaele Capasso, Fabiana Piscitelli, Barbara Romano, Olga A Parisi, Stefania Finizio, Anna Lauritano, Vincenzo Di Marzo, Angelo A Izzo, Francesca Borrelli
Anecdotal and scientific evidence suggests that Cannabis use may be beneficial in inflammatory bowel disease (IBD) patients. Here, we have investigated the effect of a standardized Cannabis sativa extract with high content of cannabidiol (CBD), here named CBD BDS for "CBD botanical drug substance," on mucosal inflammation and hypermotility in mouse models of intestinal inflammation. Colitis was induced in mice by intracolonic administration of dinitrobenzenesulfonic acid (DNBS). Motility was evaluated in the experimental model of intestinal hypermotility induced by irritant croton oil...
2016: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/27637361/tracking-dabbing-using-search-query-surveillance-a-case-study-in-the-united-states
#14
Zhu Zhang, Xiaolong Zheng, Daniel Dajun Zeng, Scott J Leischow
BACKGROUND: Dabbing is an emerging method of marijuana ingestion. However, little is known about dabbing owing to limited surveillance data on dabbing. OBJECTIVE: The aim of the study was to analyze Google search data to assess the scope and breadth of information seeking on dabbing. METHODS: Google Trends data about dabbing and related topics (eg, electronic nicotine delivery system [ENDS], also known as e-cigarettes) in the United States between January 2004 and December 2015 were collected by using relevant search terms such as "dab rig...
September 16, 2016: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/27477564/potion-of-poison-cannabis-oil
#15
Nataly Martini
No abstract text is available yet for this article.
June 2016: Journal of Primary Health Care
https://www.readbyqxmd.com/read/27471078/limitations-to-the-dutch-cannabis-toleration-policy-assumptions-underlying-the-reclassification-of-cannabis-above-15-thc
#16
Margriet Van Laar, Peggy Van Der Pol, Raymond Niesink
The Netherlands has seen an increase in Δ9-tetrahydrocannabinol (THC) concentrations from approximately 8% in the 1990s up to 20% in 2004. Increased cannabis potency may lead to higher THC-exposure and cannabis related harm. The Dutch government officially condones the sale of cannabis from so called 'coffee shops', and the Opium Act distinguishes cannabis as a Schedule II drug with 'acceptable risk' from other drugs with 'unacceptable risk' (Schedule I). Even in 1976, however, cannabis potency was taken into account by distinguishing hemp oil as a Schedule I drug...
August 2016: International Journal on Drug Policy
https://www.readbyqxmd.com/read/27268223/medicinal-cannabis-principal-cannabinoids-concentration-and-their-stability-evaluated-by-a-high-performance-liquid-chromatography-coupled-to-diode-array-and-quadrupole-time-of-flight-mass-spectrometry-method
#17
Cinzia Citti, Giuseppe Ciccarella, Daniela Braghiroli, Carlo Parenti, Maria Angela Vandelli, Giuseppe Cannazza
In the last few years, there has been a boost in the use of cannabis-based extracts for medicinal purposes, although their preparation procedure has not been standardized but rather decided by the individual pharmacists. The present work describes the development of a simple and rapid high performance liquid chromatography method with UV detection (HPLC-UV) for the qualitative and quantitative determination of the principal cannabinoids (CBD-A, CBD, CBN, THC and THC-A) that could be applied to all cannabis-based medicinal extracts (CMEs) and easily performed by a pharmacist...
September 5, 2016: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/27242881/variability-in-seed-traits-in-a-collection-of-cannabis-sativa-l-genotypes
#18
Incoronata Galasso, Roberto Russo, Sergio Mapelli, Elena Ponzoni, Ida M Brambilla, Giovanna Battelli, Remo Reggiani
The seed of Cannabis sativa L. is an expanding source of proteins and oil for both humans and animals. In this study, the proximate composition of a collection of hemp cultivars and accessions of different geographical origins grown under the same conditions for 1 year was analyzed in order to identify potential accessions to improve hemp cultivars. Fatty acids, tocopherols, and antinutritional components, as well as concentrations of crude protein and oil were quantified. The seed oil concentrations varied between 285 and 360 g kg(-1) dry seed (DS), while crude protein ranged between 316 and 356 g kg(-1) dry matter (DM)...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27228348/drug-vaping-applied-to-cannabis-is-cannavaping-a-therapeutic-alternative-to-marijuana
#19
Vincent Varlet, Nicolas Concha-Lozano, Aurélie Berthet, Grégory Plateel, Bernard Favrat, Mariangela De Cesare, Estelle Lauer, Marc Augsburger, Aurélien Thomas, Christian Giroud
Therapeutic cannabis administration is increasingly used in Western countries due to its positive role in several pathologies. Dronabinol or tetrahydrocannabinol (THC) pills, ethanolic cannabis tinctures, oromucosal sprays or table vaporizing devices are available but other cannabinoids forms can be used. Inspired by the illegal practice of dabbing of butane hashish oil (BHO), cannabinoids from cannabis were extracted with butane gas, and the resulting concentrate (BHO) was atomized with specific vaporizing devices...
May 26, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27076277/polyphenolic-compounds-and-antioxidant-activity-of-cold-pressed-seed-oil-from-finola-cultivar-of-cannabis-sativa-l
#20
Antonella Smeriglio, Enza M Galati, Maria T Monforte, Francesco Lanuzza, Valeria D'Angelo, Clara Circosta
The aim of this study was to characterize the polyphenolic compounds and antioxidant activity of cold-pressed seed oil from Finola cultivar of industrial hemp (Cannabis sativa L.). Several methodologies have been employed to evaluate the in vitro antioxidant activity of Finola hempseed oil (FHSO) and both lipophilic (LF) and hydrophilic fractions (HF). The qualitative and quantitative composition of the phenolic fraction of FHSO was performed by HPLC analyses. From the results is evident that FHSO has high antioxidative activity, as measured by DPPH radical (146...
August 2016: Phytotherapy Research: PTR
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