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https://www.readbyqxmd.com/read/27903207/direct-cerebral-perfusion-and-cooling-in-experimental-cardiac-arrest
#1
Rinaldo Bellomo, Bruno Marino, Peter Angelopoulos, Scott Carson, Glenn Eastwood, Junko Kosaka, Naoya Iguchi, Andrew Hilton, Clive May
BACKGROUND: Cerebral protection is a key priority during cardiac arrest (CA). However, current approaches are suboptimal. OBJECTIVE: To test whether direct perfusion and cooling of the anterior cerebral circulation by means of cerebral vessel cannulation and extracorporeal membrane oxygenation (ECMO) increases cerebral oxygenation and induces cerebral hypothermia during CA. METHODS: We performed proof-of-concept animal experiments in sheep...
December 2016: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://www.readbyqxmd.com/read/27902847/food-deprivation-facilitates-reinstatement-of-morphine-induced-conditioned-place-preference-role-of-intra-accumbal-dopamine-d2-like-receptors-in-associating-reinstatement-of-morphine-cpp-with-stress
#2
Fatemeh Sadeghzadeh, Vahab Babapour, Abbas Haghparast
The high rate of relapse to drug use is one of the main problems in the treatment of addiction. Stress plays the essential role in drug abuse and relapse; nevertheless, little is known about the mechanisms underlying stress and relapse. Accordingly, the effects of intra-accumbal administration of Sulpiride, as a dopamine D2-like receptor antagonist, on an ineffective morphine dose+food deprivation(FD)- and morphine priming-induced reinstatement of conditioned place preference (CPP). 104 adult male albino Wistar rats weighing 200-280g were bilaterally implanted by cannula into the nucleus accumbens (NAc)...
November 30, 2016: Synapse
https://www.readbyqxmd.com/read/27900560/serum-leptin-obestatin-and-ghrelin-levels-and-gastric-emptying-rates-of-liquid-and-solid-meals-in-non-obese-rats-with-roux-en-y-bypass-surgery-or-prosthesis-placement-implications-for-the-role-of-vagal-afferents
#3
Yunus Yavuz, Zarife Nigar Özdemir Kumral, Gülsün Memi, Özge Dağdeviren Çevik, Cumhur Yeğen, Berrak Ç Yeğen
BACKGROUND: The present study aimed to investigate the effects of Roux-en-Y gastric bypass (RYGB) and prosthesis placement on gastric emptying rate in conjunction with serum ghrelin-obestatin-leptin responses in non-obese rats with intact or denervated afferent innervation. METHODS: Under anesthesia, male Sprague-Dawley rats underwent either sham operation, RYGB, prosthesis, and/or Gregory cannula placement. Three weeks later, liquid or solid gastric emptying tests were performed and serum ghrelin, leptin and obestatin levels were measured...
November 29, 2016: Obesity Surgery
https://www.readbyqxmd.com/read/27899530/deep-breathing-improves-end-tidal-carbon-dioxide-monitoring-of-an-oxygen-nasal-cannula-based-capnometry-device-in-subjects-extubated-after-abdominal-surgery
#4
Shunsuke Takaki, Kenji Mizutani, Moeka Fukuchi, Tasuku Yoshida, Masahumi Idei, Yuko Matsuda, Yoshikazu Yamaguchi, Tetsuya Miyashita, Takeshi Nomura, Osamu Yamaguchi, Takahisa Goto
BACKGROUND: Capnometry detects hypoventilation earlier than pulse oximetry while supplemental oxygen is being administered. We compared the end-tidal CO2 (PETCO2 ) measured using a newly developed oxygen nasal cannula with a CO2-sampling port and the PaCO2 in extubated subjects after abdominal surgery. We also investigated whether the difference between PaCO2 and PETCO2 is affected by resting, by spontaneous breathing with the mouth consciously closed, and by deep breathing with the mouth closed...
November 29, 2016: Respiratory Care
https://www.readbyqxmd.com/read/27899105/non-invasive-mechanical-ventilation-after-heart-surgery-in-children
#5
Sarah Fernández Lafever, Blanca Toledo, Miguel Leiva, Maite Padrón, Marina Balseiro, Angel Carrillo, Jesús López-Herce
BACKGROUND: The purpose of the study was to analyze the characteristics and evolution of non-invasive mechanical ventilation (NIV) in the postoperative period of heart surgery in children. METHODS: Retrospective observational study including all children requiring NIV after heart surgery in a single center pediatric intensive care unit (PICU) between 2001 and 2012. Demographic characteristics, ventilation parameters and outcomes were registered, comparing the first 6 years of the study with the last 6 years...
November 29, 2016: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/27898917/chemical-composition-and-standardized-ileal-amino-acid-digestibility-of-eight-genotypes-of-rye-fed-to-growing-pigs
#6
E J P Strang, M Eklund, P Rosenfelder, N Sauer, J K Htoo, R Mosenthin
A study with growing pigs was conducted to determine the chemical composition, physical characteristics, and standardized ileal digestibility (SID) of CP and AA of 8 rye genotypes that have recently been added to the German Descriptive Variety List. Eight barrows with an initial BW of 24 ± 2 kg were fitted with T-cannulas at the distal ileum and allotted to an 8 × 8 Latin square design with 8 periods of 6 d each and 8 pigs receiving 8 different diets. The N-free method was used to determine the basal ileal endogenous CP and AA losses...
September 2016: Journal of Animal Science
https://www.readbyqxmd.com/read/27898860/effects-of-collection-time-on-flow-of-chromium-and-dry-matter-and-on-basal-ileal-endogenous-losses-of-amino-acids-in-growing-pigs
#7
B G Kim, Y Liu, H H Stein
The objectives of this experiment were to examine the diurnal patterns of chromium and DM flow at the distal ileum of pigs and to determine the effect of collection time on basal ileal endogenous losses (BEL) of CP and AA. Eight barrows with an initial BW of 34.6kg (SD = 2.1) were individually fitted with a T-cannula in the distal ileum and randomly allotted to a replicated 4× 4 Latin square design with 4 diets and 4 periods in each square. Three diets contained either corn, soybean meal, or distillers dried grains with solubles as the sole source of CP and AA...
October 2016: Journal of Animal Science
https://www.readbyqxmd.com/read/27898849/effects-of-feed-intake-and-dietary-nutrient-density-on-apparent-ileal-and-total-tract-digestibility-of-nutrients-and-gross-energy-for-growing-pigs
#8
J B Liu, Z Q Liu, L Chen, H F Zhang
The present study was conducted to investigate the effects of feed intake (FI) and dietary nutrient concentration on the determination of apparent ileal digestibility (AID) and apparent total tract digestibility (ATTD) of nutrients and GE for growing pigs. A total of 48 growing pigs (40.7 ± 1.3 kg initial BW) were surgically fitted with simple T-cannulas at the distal ileum and assigned to 6 treatment groups in a 2 × 3 factorial arrangement of 2 diets (a low-nutrient-density [LND] diet or a normal-nutrient-density [NND] diet) and 3 FI levels (3, 4 or 5% of BW per day)...
October 2016: Journal of Animal Science
https://www.readbyqxmd.com/read/27898843/influence-of-protein-nutrition-and-virginiamycin-supplementation-on-feedlot-growth-performance-and-digestive-function-of-calf-fed-holstein-steers
#9
J Salinas-Chavira, A Barreras, A Plascencia, M F Montano, J D Navarrete, N Torrentera, R A Zinn
Two experiments were conducted to examine the influence of protein and virginiamycin (VM) supplementation on feedlot growth performance, digestion, and metabolizable AA (MAA) supply of calf-fed Holstein steers. Growth performance and dietary energetics were evaluated in 120 Holstein steers (127 ± 9 kg). During the initial 112-d feeding period, a steam-flaked corn-based diet was balanced to meet either 100% (MAB) or 87% (UREA) of MAA requirements. Diets were supplemented with or without 22.5 mg/kg VM in a 2 × 2 factorial arrangement...
October 2016: Journal of Animal Science
https://www.readbyqxmd.com/read/27898454/transvaginal-pelvic-floor-muscle-injection-technique-a-cadaver-study
#10
Priyanka Gupta, Michael Ehlert, Larry T Sirls, Kenneth Peters
INTRODUCTION: Women with pelvic floor dysfunction can have tender areas on vaginal examination, which can be treated with trigger-point injections. There are no publications to evaluate the accuracy of pelvic floor muscle injections. METHODS: Trigger-point injections were performed on 2 fresh cadaveric pelvises using a curved nasal cannula guide and 7-in spinal needle. This was performed using our standard template of 2 sets of injections at the 1-, 3-, and 5-o'clock positions distally and proximally...
November 28, 2016: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/27897734/how-to-insert-a-peripheral-cannula
#11
Sally Jane Shaw
Rationale and key points This article aims to assist practitioners to undertake the safe and effective insertion of a peripheral cannula. It provides information on best practice related to peripheral cannulation with an open-ported safety cannula. The same principles for practice apply to non-ported open safety cannulae. » Peripheral cannulation enables venous access, the administration of intravenous medication, infusion therapy and total parenteral nutrition. It also enables blood samples to be obtained...
November 16, 2016: Nursing Standard
https://www.readbyqxmd.com/read/27896179/clinical-factors-associated-with-the-non-operative-airway-management-of-patients-with-robin-sequence
#12
Frank P Albino, Benjamin C Wood, Kevin D Han, Sojung Yi, Mitchel Seruya, Gary F Rogers, Albert K Oh
BACKGROUND: The indications for surgical airway management in patients with Robin sequence (RS) and severe airway obstruction have not been well defined. While certain patients with RS clearly require surgical airway intervention and other patients just as clearly can be managed with conservative measures alone, a significant proportion of patients with RS present with a more confusing and ambiguous clinical course. The purpose of this study was to describe the clinical features and objective findings of patients with RS whose airways were successfully managed without surgical intervention...
November 2016: Archives of Plastic Surgery
https://www.readbyqxmd.com/read/27895987/characterization-of-fiber-optic-light-delivery-and-light-induced-temperature-changes-in-a-rodent-brain-for-precise-optogenetic-neuromodulation
#13
Younghoon Shin, Minsu Yoo, Hyung-Sun Kim, Sung-Ki Nam, Hyoung-Ihl Kim, Sun-Kyu Lee, Sohee Kim, Hyuk-Sang Kwon
Understanding light intensity and temperature increase is of considerable importance in designing or performing in vivo optogenetic experiments. Our study describes the optimal light power at target depth in the rodent brain that would maximize activation of light-gated ion channels while minimizing temperature increase. Monte Carlo (MC) simulations of light delivery were used to provide a guideline for suitable light power at a target depth. In addition, MC simulations with the Pennes bio-heat model using data obtained from measurements with a temperature-measuring cannula having 12...
November 1, 2016: Biomedical Optics Express
https://www.readbyqxmd.com/read/27894561/apneic-oxygenation-may-not-prevent-severe-hypoxemia-during-rapid-sequence-intubation-a-retrospective-helicopter-emergency-medical-service-study
#14
Sattha Riyapan, Jeffrey Lubin
OBJECTIVE: This study sought to determine the effectiveness of apneic oxygenation in preventing hypoxemia during prehospital rapid sequence intubation (RSI). METHODS: We performed a case-cohort study using a pre-existing database looking at intubation management by a single helicopter emergency medical service between July 2013 and June 2015. Apneic oxygenation using high-flow nasal cannula (15 L/min) was introduced to the standard RSI protocol in July 2014. Severe hypoxemia was defined as an incidence of oxygen saturation less than 90%...
November 2016: Air Medical Journal
https://www.readbyqxmd.com/read/27890757/percutaneous-endoscopic-removal-of-a-lumbar-epidural-angiolipoma-via-interlaminar-approach-a-technical-report
#15
Guang-Yu Ying, Ying Yao, Fang Shen, Yu-Cheng Ren, Chien-Min Chen, Yong-Jian Zhu
BACKGROUND: Percutaneous endoscopic technique has been routinely used in the treatment of disk herniation while there are few reports on its application in the management of intraspinal tumors. We presented here the first case report of lumbar epidural angiolipoma that was totally removed by percutaneous endoscopy. CASE DESCRIPTION: A 63-year-old man presented with 4-month history of progressively worsening low back pain was admitted to our hospital. No abnormal neurological finding was noticed on physical examination and magnetic resonance imaging demonstrated a dorsally located L2-L3 epidural lesion, suggestive of a non-infiltrating angiolipoma...
November 24, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27888983/high-flow-nasal-cannula-versus-conventional-oxygen-therapy-and-non-invasive-ventilation-in-adults-with-acute-hypoxemic-respiratory-failure-a-systematic-review
#16
REVIEW
Chi Chan Lee, Dhruti Mankodi, Sameer Shaharyar, Sharmila Ravindranathan, Mauricio Danckers, Pablo Herscovici, Molly Moor, Gustavo Ferrer
INTRODUCTION: Humidified oxygen via a high flow nasal cannula (HFNC) is a form of supplemental oxygen therapy that has significant theoretical advantages over conventional oxygen therapy (COT). However, the clinical role of HFNC in acute hypoxemic respiratory failure (AHRF) has not been well established. This review compares the efficacy of HFNC with COT and non-invasive ventilation (NIV) in patients with AHRF. METHODS: Studies reviewed were selected based on relevance from a systematic literature search conducted in Medline and EMBASE to include all published original research through May 2016...
December 2016: Respiratory Medicine
https://www.readbyqxmd.com/read/27888284/attenuation-of-the-anxiogenic-effects-of-cocaine-by-5-ht1b-autoreceptor-stimulation-in-the-bed-nucleus-of-the-stria-terminalis-of-rats
#17
Adam K Klein, Michael A Brito, Sayeh Akhavan, Dylan R Flanagan, Nikki Le, Tatum Ohana, Anand S Patil, Erin M Purvis, Carl Provenzano, Alex Wei, Lucy Zhou, Aaron Ettenberg
RATIONALE: Cocaine produces significant aversive/anxiogenic actions whose underlying neurobiology remains unclear. A possible substrate contributing to these actions is the serotonergic (5-HT) pathway projecting from the dorsal raphé (DRN) to regions of the extended amygdala, including the bed nucleus of the stria terminalis (BNST) which have been implicated in the production of anxiogenic states. OBJECTIVES: The present study examined the contribution of 5-HT signaling within the BNST to the anxiogenic effects of cocaine as measured in a runway model of drug self-administration...
November 25, 2016: Psychopharmacology
https://www.readbyqxmd.com/read/27888019/ifenprodil-infusion-in-agranular-insular-cortex-alters-social-behavior-and-vocalizations-in-rats-exposed-to-moderate-levels-of-ethanol-during-prenatal-development
#18
Clark W Bird, Daniel Barto, Christy M Magcalas, Carlos I Rodriguez, Tia Donaldson, Suzy Davies, Daniel D Savage, Derek A Hamilton
Moderate exposure to alcohol during development leads to subtle neurobiological and behavioral effects classified under the umbrella term fetal alcohol spectrum disorders (FASDs). Alterations in social behaviors are a frequently observed consequence of maternal drinking, as children with FASDs display inappropriate aggressive behaviors and altered responses to social cues. Rodent models of FASDs mimic the behavioral alterations seen in humans, with rats exposed to ethanol during development displaying increased aggressive behaviors, decreased social investigation, and altered play behavior...
November 22, 2016: Behavioural Brain Research
https://www.readbyqxmd.com/read/27886577/high-flow-nasal-cannula-oxygen-therapy-vs-conventional-oxygen-therapy-in-cardiac-surgical-patients-a-meta-analysis
#19
Youfeng Zhu, Haiyan Yin, Rui Zhang, Jianrui Wei
INTRODUCTION: The use of high-flow nasal cannula (HFNC) for the treatment of many diseases has gained increasing popularity. In the present meta-analysis, we aimed to assess the efficacy and safety of HFNCs compared with conventional oxygen therapy (COT) in adult postextubation cardiac surgical patients. METHOD: We reviewed the Embase, PubMed, Cochrane Central Register of Controlled Trials, Wanfang databases, and the China National Knowledge Infrastructure. Two investigators independently collected the data and assessed the quality of each study...
November 9, 2016: Journal of Critical Care
https://www.readbyqxmd.com/read/27879385/fio2-in-an-adult-model-simulating-high-flow-nasal-cannula-therapy
#20
Yusuke Chikata, Mutsuo Onodera, Jun Oto, Masaji Nishimura
BACKGROUND: High-flow nasal cannula therapy (HFNC) is widely used for patients with acute respiratory failure. HFNC has a number of physiological effects. Although FIO2 is considered to be constant, because HFNC is an open system, FIO2 varies according to inspiratory flow, tidal volume (VT), and HFNC gas flow. We investigated the influence of HFNC gas flow and other respiratory parameters on FIO2 during HFNC. METHODS: We evaluated an HFNC system and, for comparison, a conventional oxygen therapy system...
November 22, 2016: Respiratory Care
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