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Allograft ligament

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https://www.readbyqxmd.com/read/28301224/increased-risk-of-revision-after-anterior-cruciate-ligament-reconstruction-with-soft-tissue-allografts-compared-with-autografts-graft-processing-and-time-make-a-difference
#1
Gregory B Maletis, Jason Chen, Maria C S Inacio, Rebecca M Love, Tadashi T Funahashi
BACKGROUND: The optimal graft for anterior cruciate ligament reconstruction (ACLR) remains controversial. PURPOSE: To compare the risk of aseptic revision between bone-patellar tendon-bone (BPTB) autografts, hamstring autografts, and soft tissue allografts. STUDY DESIGN: Cohort study; Level of evidence, 2. METHODS: Prospectively collected ACLR cases reconstructed with BPTB autografts, hamstring autografts, and soft tissue allografts were identified using the Kaiser Permanente ACLR Registry...
March 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28298067/incidence-of-second-anterior-cruciate-ligament-tears-1990-2000-and-associated-factors-by-geographic-locale
#2
Nathan D Schilaty, Nathaniel A Bates, Thomas L Sanders, Aaron J Krych, Michael J Stuart, Timothy E Hewett
BACKGROUND: Second anterior cruciate ligament (ACL) tears after reconstruction occur at a reported rate of 20% to 30%. This high frequency indicates that there may be factors that predispose an athlete to graft failure and ACL tears of the contralateral knee. PURPOSE: To determine the incidence of second ACL injuries in a geographic population-based cohort over a 10-year observation period. STUDY DESIGN: Descriptive epidemiological study. METHODS: International Classification of Diseases, 9th Revision (ICD-9) codes relevant to the diagnosis of an ACL tear and the procedure code for ACL reconstruction were searched across the Rochester Epidemiology Project, a multidisciplinary county database, between the years of 1990 and 2000...
March 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28298052/allograft-augmentation-of-hamstring-autograft-for-younger-patients-undergoing-anterior-cruciate-ligament-reconstruction
#3
Cale A Jacobs, Jeremy M Burnham, Eric Makhni, Chaitu S Malempati, Eric Swart, Darren L Johnson
BACKGROUND: Younger patients and those with smaller hamstring autograft diameters have been shown to be at significantly greater risk of graft failure after anterior cruciate ligament (ACL) reconstruction. To date, there is no information in the literature about the clinical success and/or cost-effectiveness of increasing graft diameter by augmenting with semitendinosus allograft tissue for younger patients. HYPOTHESIS: Hybrid hamstring grafts are a cost-effective treatment option because of a reduced rate of graft failure...
March 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28295121/outcomes-at-a-minimum-of-2-years-after-medial-collateral-ligament-reconstruction-using-partial-thickness-quadriceps-tendon-bone-autograft
#4
Iftach Hetsroni, Gideon Mann
This study reports outcomes at a minimum of 2 years after a technique using quadriceps tendon-bone autograft for medial collateral ligament reconstruction. This technique effectively restored medial stability in medial collateral ligament-deficient knees. It is particularly valuable when nonirradiated allograft is unavailable or harvesting medial knee restraints (semitendinosus) for medial collateral ligament reconstruction is to be avoided. [Orthopedics. 201x; xx(x):xx-xx.].
March 14, 2017: Orthopedics
https://www.readbyqxmd.com/read/28277740/increased-risk-of-revision-after-anterior-cruciate-ligament-reconstruction-with-bone-patellar-tendon-bone-allografts-compared-with-autografts
#5
Gregory B Maletis, Jason Chen, Maria C S Inacio, Rebecca M Love, Tadashi T Funahashi
BACKGROUND: The use of allograft tissue for anterior cruciate ligament reconstruction (ACLR) remains controversial. PURPOSE: To compare the risk of aseptic revision between bone-patellar tendon-bone (BPTB) autografts and BPTB allografts. STUDY DESIGN: Cohort study; Level of evidence, 2. METHODS: A retrospective cohort study of prospectively collected data was conducted using the Kaiser Permanente ACLR Registry. A cohort of patients who underwent primary unilateral ACLR with BPTB autografts and BPTB allografts was identified...
March 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28275205/a-comparative-study-of-effect-of-autograft-versus-allograft-anterior-cruciate-ligament-reconstruction-onexpressions-ofloxsand-mmps
#6
Wei-Ming Wang, Xiao-Jun Ma, Shi-Bo Huang, Liu-Bao Ren, Yu-Peng Liu
This study aimed to compare the effect of autograft or allograft anterior cruciate ligament (ACL) reconstruction on the expressions of LOXs and MMPs in a New Zealand white rabbit model. New Zealand white rabbits were divided randomly into control, sham, autograft and allograft groups At the 4th and 8th week after operation, biomechanical testing was performed to measure the primary length, cross-sectional area, maximum tensile load and stiffness of ACL, and HE staining was used to observe cell morphology and fibre alignment of ACL...
March 8, 2017: Bioscience Reports
https://www.readbyqxmd.com/read/28272928/prospective-clinical-and-radiographic-outcomes-after-concomitant-anterior-cruciate-ligament-reconstruction-and-meniscal-allograft-transplantation-at-a-mean-5-year-follow-up
#7
Bryan M Saltzman, Maximilian A Meyer, Alexander E Weber, Sarah G Poland, Adam B Yanke, Brian J Cole
BACKGROUND: Concomitant anterior cruciate ligament reconstruction and meniscal allograft transplantation (ACLR/MAT) has demonstrated short-term success in small, retrospective cohort studies. Patient- and disease-specific predictors of success after ACLR/MAT are largely unknown. PURPOSE: To (1) prospectively evaluate the subjective and objective clinical and radiographic outcomes after ACLR/MAT and (2) conduct a subgroup analysis to identify patient- or disease-related factors that correlate with failure...
March 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28272925/a-biomechanical-comparison-of-allograft-tendons-for-ligament-reconstruction
#8
Jeremiah E Palmer, Joseph P Russell, Jason Grieshober, Abigail Iacangelo, Benjamin A Ellison, T Dylan Lease, Hyunchul Kim, R Frank Henn, Adam H Hsieh
BACKGROUND: Allograft tendons are frequently used for ligament reconstruction about the knee, but they entail availability and cost challenges. The identification of other tissues that demonstrate equivalent performance to preferred tendons would improve limitations. Hypothesis/Purpose: We compared the biomechanical properties of 4 soft tissue allograft tendons: tibialis anterior (TA), tibialis posterior (TP), peroneus longus (PL), and semitendinosus (ST). We hypothesized that allograft properties would be similar when standardized by the looped diameter...
March 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28244929/can-a-novel-low-cost-simulation-model-be-used-to-teach-anterior-cruciate-ligament-graft-preparation
#9
Christopher M Brusalis, John Todd R Lawrence, Sheena C Ranade, Joy C Kerr, Nicholas Pulos, Lawrence Wells, Theodore J Ganley
BACKGROUND: This study evaluated an anterior cruciate ligament (ACL) graft preparation simulation learning model for use by orthopaedic surgery trainees. METHODS: A simulation model for ACL graft preparation was constructed using shoelace as graft material and a wooden graft preparation board that matched the dimensions of existing products. A 12-minute instructional video targeted at novice learners was created to accompany the simulation model. A prospective randomized controlled trial was conducted on orthopaedic surgery residents divided into 2 groups with equal distributions of postgraduate year (PGY) status...
February 27, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28238143/electrospun-nanofiber-scaffolds-and-their-hydrogel-composites-for-the-engineering-and-regeneration-of-soft-tissues
#10
Ohan S Manoukian, Rita Matta, Justin Letendre, Paige Collins, Augustus D Mazzocca, Sangamesh G Kumbar
Electrospinning has emerged as a simple, elegant, and scalable technique that can be used to fabricate polymeric nanofibers. Pure polymers as well as blends and composites of both natural and synthetic ones have been successfully electrospun into nanofiber matrices for many biomedical applications. Tissue-engineered medical implants, such as polymeric nanofiber scaffolds, are potential alternatives to autografts and allografts, which are short in supply and carry risks of disease transmission. These scaffolds have been used to engineer various soft tissues, including connective tissues, such as skin, ligament, and tendon, as well as nonconnective ones, such as vascular, muscle, and neural tissue...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28224072/concomitant-arthroscopic-meniscal-allograft-transplantation-and-anterior-cruciate-ligament-reconstruction
#11
Bryan M Saltzman, Justin W Griffin, Nathan Wetters, Maximilian A Meyer, Brian J Cole, Adam B Yanke
In recent decades, arthroscopic meniscal allograft transplantation (MAT) has been refined as a robust option for the treatment of evolving unicompartmental tibiofemoral arthrosis in the setting of meniscal deficiency. It is imperative that the MAT be performed in a knee with anatomic stability and alignment to reduce aberrant biomechanical forces experienced by the allograft tissue to maintain its durability. Thus, in an anterior cruciate ligament (ACL)-deficient knee, ACL reconstruction (ACLR) must be performed to restore the stable knee environment for the MAT to succeed...
October 2016: Arthroscopy Techniques
https://www.readbyqxmd.com/read/28224070/combined-particulated-juvenile-cartilage-allograft-transplantation-and-medial-patellofemoral-ligament-reconstruction-for-symptomatic-chondral-defects-in-the-setting-of-recurrent-patellar-instability
#12
Armin Arshi, Dean Wang, Kristofer J Jones
Successful management of patellar osteochondral lesions has proved difficult, with unreliable outcomes reported using traditional cartilage repair and restoration procedures. Unique considerations for this type of defect include the multiplanar contours of the articular surface of the patella, high compressive and shear forces with knee range of motion that may disrupt graft healing, and the potential need for concomitant surgery to address patellar malalignment and instability. We describe our preferred method for treatment of a symptomatic chondral defect in the setting of recurrent patellar instability using particulated juvenile articular cartilage allograft transplantation and medial patellofemoral ligament reconstruction with semitendinosus allograft...
October 2016: Arthroscopy Techniques
https://www.readbyqxmd.com/read/28224069/allograft-anterior-cruciate-ligament-reconstruction-utilizing-internal-brace-augmentation
#13
Patrick A Smith, Jordan A Bley
Anterior cruciate ligament (ACL) tears are among the most common sports-related injuries. Although studies have reported reliable outcomes with allograft tissue, several studies have shown a higher failure rate in younger patients. Although ACL graft augmentation has been met with varying levels of success, internal bracing of an allograft represents a promising area in ACL reconstruction. The purpose of this article is to detail allograft preparation involving a collagen-coated, ultrahigh-molecular-weight polyethylene/polyester suture tape as an internal brace augmentation for ACL reconstruction using the all-inside ACL GraftLink Technique (Arthrex, Naples, FL)...
October 2016: Arthroscopy Techniques
https://www.readbyqxmd.com/read/28211291/a-biomechanical-analysis-of-tibial-acl-reconstruction-with-graft-length-mismatch
#14
Evan B Gaines, Diana Lau, Qais Naziri, Westley Hayes, Julio J Jauregui, Bhaveen H Kapadia, William P Urban, Bashir A Zikria
INTRODUCTION: The incidence of graft length mismatch (GLM) during anterior cruciate ligament (ACL) reconstruction is reported to be up to 13%, with a rate of 20% when using bone-patellar tendon-bone (BPTB) allografts. Multiple techniques have been described to accommodate for the longer BPTB graft. As no study has compared the biomechanical properties of these methods (with cyclic loading), we evaluated the strength of four different surgical techniques used to accommodate for GLM during ACL reconstruction...
January 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28195744/-proprietary-processed-allografts
#15
Troy A Roberson, Jeffrey T Abildgaard, Douglas J Wyland, Paul C Siffri, Stephen P Geary, Richard J Hawkins, John M Tokish
BACKGROUND: The processing of allograft tissues in anterior cruciate ligament (ACL) reconstruction continues to be controversial. While high-dose irradiation of grafts has received scrutiny for high failure rates, lower dose irradiation and "proprietary-based" nonirradiated sterilization techniques have become increasingly popular, with little in the literature to evaluate their outcomes. Recent studies have suggested that the specifics of allograft processing techniques may be a risk factor for higher failure rates...
February 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28178094/reconstruction-of-symptomatic-congenital-anterior-cruciate-ligament-insufficiency
#16
Brant C Sachleben, Adam Y Nasreddine, Jeffrey J Nepple, Frances A Tepolt, James R Kasser, Mininder S Kocher
BACKGROUND: Hypoplasia or congenital absence of the anterior cruciate ligament (ACL) is a rare disorder occurring in ∼1 in every 6000 births. Although some patients with hypoplasia or agenesis of the ACL may not complain of instability, others desire to participate in more demanding activities that require the stability of a competent ACL. There are limited reports of surgical treatment of this patient population. The purpose of this study was to report ACL reconstruction in a case series of patients with symptomatic congenital ACL deficiency...
February 7, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28159425/magnetic-resonance-imaging-evaluation-of-physeal-violation-in-adolescents-after-transphyseal-anterior-cruciate-ligament-reconstruction
#17
Joon-Ho Wang, Kang-Min Son, Dae-Hee Lee
PURPOSE: To quantify and compare the amount and location of physis violation of the distal femur and proximal tibia after transphyseal anterior cruciate ligament (ACL) reconstruction in skeletally immature patients. METHODS: This study included 19 patients with open physes of the distal femur and proximal tibia who underwent ACL reconstruction with tibialis anterior allografts. Physeal tunnel volume and location on the growth plate, as well as obliquity to the growth plate, were measured by 3-dimensional postoperative magnetic resonance imaging of the distal femur and proximal tibia...
January 31, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28109536/biomechanical-properties-of-bovine-tendon-xenografts-treated-with-a-modern-processing-method
#18
Henry B Colaço, Breck R Lord, Diane L Back, Andrew J Davies, Andrew A Amis, Adil Ajuied
Xenograft tendons have been used in few human studies, with variable results. With the advent of novel tissue processing techniques, which may mitigate against an immune-mediated rejection response without adversely affecting mechanical properties, there may now be a clinical role for xenograft tendons, particularly in knee ligament reconstruction. We hypothesize that 'BioCleanse®' processed bovine extensor digitorum medialis (EDM) tendons exhibit favorable time-zero pre-implantation biomechanical characteristics when compared to both unprocessed bovine EDM tendons and BioCleanse® processed human cadaveric allograft tibialis anterior tendons...
February 28, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28028569/functional-testing-and-return-to-sport-following-stabilization-surgery-for-recurrent-lateral-patellar-instability-in-competitive-athletes
#19
Aaron J Krych, Michael P O'Malley, Nick R Johnson, Rohith Mohan, Timothy E Hewett, Michael J Stuart, Diane L Dahm
PURPOSE: Medial patellofemoral ligament (MPFL) reconstruction and tibial tubercle osteotomy are commonly used to treat recurrent lateral patellar instability, yet there are limited available data on return to sport (RTS) following these procedures. The purpose of this study is to evaluate patient factors associated with excellent functional outcomes, including successful RTS, following surgical stabilization including MPFL reconstruction in competitive athletes with recurrent lateral patellar instability...
December 27, 2016: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28024306/a-canine-arthroscopic-anterior-cruciate-ligament-reconstruction-model-for-study-of-synthetic-augmentation-of-tendon-allografts
#20
James L Cook, Pat Smith, James P Stannard, Ferris Pfeiffer, Keiichi Kuroki, Chantelle C Bozynski, Cristi Cook
Novel graft types, fixation methods, and means for augmenting anterior cruciate ligament (ACL) reconstructions require preclinical validation prior to safe and effective clinical application. The objective of this study was to describe and validate a translational canine model for all-inside arthroscopic complete ACL reconstruction using a quadriceps tendon allograft with internal brace (QTIB). With institutional approval, adult research hounds underwent complete transection of the native ACL followed by all-inside ACL reconstruction using the novel QTIB construct with suspensory fixation (n = 10)...
December 26, 2016: Journal of Knee Surgery
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